Method Of Synthesizing 4' Phosphate Analog Nucleotide Phosphoramidite

Abstract: Methods are disclosed for making a 4'-phosphate analog phosphoramidite known as MeMOP, which can be used in the synthesis of oligonucleotides such as therapeutic oligonucleotides.

Patent Information

Application #

Filing Date

22 May 2025

Publication Number

24/2025

Publication Type

INA

Invention Field

BIOTECHNOLOGY

Status

Email

Parent Application

Applicants

ELI LILLY AND COMPANY

Lilly Corporate Center Indianapolis, Indiana 46285

Inventors

1. FRANK, Scott Alan

c/o ELI LILLY AND COMPANY P.O. Box 6288 Indianapolis, Indiana 46206-6288

2. RIZZO, John Robert

c/o ELI LILLY AND COMPANY P.O. Box 6288 Indianapolis, Indiana 46206-6288

Specification

Documents

Application Documents

#	Name	Date
1	202517049220-STATEMENT OF UNDERTAKING (FORM 3) [22-05-2025(online)].pdf	2025-05-22
2	202517049220-REQUEST FOR EXAMINATION (FORM-18) [22-05-2025(online)].pdf	2025-05-22
3	202517049220-POWER OF AUTHORITY [22-05-2025(online)].pdf	2025-05-22
4	202517049220-FORM 18 [22-05-2025(online)].pdf	2025-05-22
5	202517049220-FORM 1 [22-05-2025(online)].pdf	2025-05-22
6	202517049220-FIGURE OF ABSTRACT [22-05-2025(online)].pdf	2025-05-22
7	202517049220-DRAWINGS [22-05-2025(online)].pdf	2025-05-22
8	202517049220-DECLARATION OF INVENTORSHIP (FORM 5) [22-05-2025(online)].pdf	2025-05-22
9	202517049220-COMPLETE SPECIFICATION [22-05-2025(online)].pdf	2025-05-22
10	202517049220-FORM 3 [26-09-2025(online)].pdf	2025-09-26
11	202517049220-Proof of Right [29-09-2025(online)].pdf	2025-09-29