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Process To Make Glp1 Ra And Intermediates Therefor
Abstract: The present invention relates to the synthesis of 3-[(1S,2S)-1-[5-[(4S)-2,2-dimethyloxan-4-yl]-2-[(4S)-2-(4-fluoro-3,5-dimethylphenyl)-3-[3-(4-fluoro-1-methylindazol-5-yl)-2-oxoimidazol-1-yl]-4-methyl-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-5-carbonyl]indol-1-yl]-2-methylcyclopropyl]-4H-1,2,4-oxadiazol-5-one, or a salt thereof, and related synthetic intermediate compounds.
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
19 June 2025
Publication Number
27/2025
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
Parent Application
Applicants
ELI LILLY AND COMPANY
Lilly Corporate Center
Indianapolis, Indiana 46285
CHUGAI SEIYAKU KABUSHIKI KAISHA
135, Komakado 1-chome, Gotemba-shi
Shizuoka 1412-8513
Inventors
1. ALLIAN, Ayman D.
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
2. BERGLUND, Kenneth Derek
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
3. COLE, Kevin Paul
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
4. DAVIS, Ashlee Jeanette
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
5. HESS, Molly
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
6. JEMISON, Adrianna
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
7. KERR, Mark Steven
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
8. MACK, Audrey Grace
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
9. ORTIZ-MEDINA, Xavier A.
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
10. REMICK, David Michael
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
11. STARKEY, Derek Robert
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
12. VAID, Radhe Krishan
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
13. YANG, Qiang
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
14. KAWAGISHI, Fumiki
c/o Chugai Seiyaku Kabushiki Kaisha
135, Komakado 1-chome, Gotemba-shi
Shizuoka 1412-8513
15. EMURA, Takashi
c/o Chugai Seiyaku Kabushiki Kaisha
135, Komakado 1-chome, Gotemba-shi
Shizuoka 1412-8513
16. TSUCHIYA, Satoshi
c/o Chugai Seiyaku Kabushiki Kaisha
135, Komakado 1-chome, Gotemba-shi
Shizuoka 1412-8513
17. WADAMOTO, Manabu
c/o Chugai Seiyaku Kabushiki Kaisha
135, Komakado 1-chome, Gotemba-shi
Shizuoka 1412-8513
18. YAMAWAKI, Minoru
c/o Chugai Seiyaku Kabushiki Kaisha
135, Komakado 1-chome, Gotemba-shi
Shizuoka 1412-8513
Specification
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 202517058963-STATEMENT OF UNDERTAKING (FORM 3) [19-06-2025(online)].pdf | 2025-06-19 |
| 2 | 202517058963-REQUEST FOR EXAMINATION (FORM-18) [19-06-2025(online)].pdf | 2025-06-19 |
| 3 | 202517058963-PRIORITY DOCUMENTS [19-06-2025(online)].pdf | 2025-06-19 |
| 4 | 202517058963-POWER OF AUTHORITY [19-06-2025(online)].pdf | 2025-06-19 |
| 5 | 202517058963-NOTIFICATION OF INT. APPLN. NO. & FILING DATE (PCT-RO-105-PCT Pamphlet) [19-06-2025(online)].pdf | 2025-06-19 |
| 6 | 202517058963-FORM 18 [19-06-2025(online)].pdf | 2025-06-19 |
| 7 | 202517058963-FORM 1 [19-06-2025(online)].pdf | 2025-06-19 |
| 8 | 202517058963-DECLARATION OF INVENTORSHIP (FORM 5) [19-06-2025(online)].pdf | 2025-06-19 |
| 9 | 202517058963-COMPLETE SPECIFICATION [19-06-2025(online)].pdf | 2025-06-19 |
| 10 | 202517058963-RELEVANT DOCUMENTS [19-09-2025(online)].pdf | 2025-09-19 |
| 11 | 202517058963-FORM-26 [19-09-2025(online)].pdf | 2025-09-19 |
| 12 | 202517058963-FORM 13 [19-09-2025(online)].pdf | 2025-09-19 |
| 13 | 202517058963-Retyped Pages under Rule 14(1) [16-10-2025(online)].pdf | 2025-10-16 |
| 14 | 202517058963-2. Marked Copy under Rule 14(2) [16-10-2025(online)].pdf | 2025-10-16 |
| 15 | 202517058963-Proof of Right [10-11-2025(online)].pdf | 2025-11-10 |