Oligonucleotide Fragments And Methods Of Making Rnai Agents Using The

Oligonucleotide Fragments And Methods Of Making Rnai Agents Using The Same

Abstract: Intermediate compounds (i.e., oligonucleotide fragments) are disclosed for making RNAi agents, or pharmaceutically acceptable salts thereof. In addition, methods are disclosed for making single-stranded oligonucleotides by ligating two or more of the intermediate compounds herein via a hybrid chemical-enzymatic route.

Patent Information

Application #

Filing Date

26 June 2025

Publication Number

28/2025

Publication Type

INA

Invention Field

BIOTECHNOLOGY

Status

Email

Parent Application

Applicants

ELI LILLY AND COMPANY

P.O. Box 6288 Indianapolis, Indiana 46206

Inventors

1. CULY, Caleb Christopher

c/o Eli Lilly and Company P. O. Box 6288 Indianapolis, Indiana 46206

2. MAY, Scott

c/o Eli Lilly and Company P. O. Box 6288 Indianapolis, Indiana 46206

3. MOHER, Eric

c/o Eli Lilly and Company P. O. Box 6288 Indianapolis, Indiana 46206

4. TSUKANOV, Sergey

c/o Eli Lilly and Company P. O. Box 6288 Indianapolis, Indiana 46206

Specification

Documents

Application Documents

#	Name	Date
1	202517061159-STATEMENT OF UNDERTAKING (FORM 3) [26-06-2025(online)].pdf	2025-06-26
3	202517061159-Sequence Listing in txt [26-06-2025(online)].txt	2025-06-26
4	202517061159-Sequence Listing in PDF [26-06-2025(online)].pdf	2025-06-26
5	202517061159-REQUEST FOR EXAMINATION (FORM-18) [26-06-2025(online)].pdf	2025-06-26
6	202517061159-POWER OF AUTHORITY [26-06-2025(online)].pdf	2025-06-26
7	202517061159-FORM 18 [26-06-2025(online)].pdf	2025-06-26
8	202517061159-FORM 1 [26-06-2025(online)].pdf	2025-06-26
9	202517061159-DRAWINGS [26-06-2025(online)].pdf	2025-06-26
10	202517061159-DECLARATION OF INVENTORSHIP (FORM 5) [26-06-2025(online)].pdf	2025-06-26
11	202517061159-COMPLETE SPECIFICATION [26-06-2025(online)].pdf	2025-06-26
12	202517061159-Proof of Right [07-10-2025(online)].pdf	2025-10-07
13	202517061159-FORM 3 [07-10-2025(online)].pdf	2025-10-07