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Therapeutic Oligonucleotide Containing Pharmaceutical Compositions And Dosing Regimens Using The Same
Abstract: Pharmaceutical compositions are disclosed that include a double-stranded RNAi agent that modulates LPA expression or its pharmaceutically acceptable salt thereof in water. Doses and dosing regimens for such RNAi agents also are disclosed that include administering doses from about 4 mg to about 608 mg at a frequency of monthly to yearly.
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
11 July 2025
Publication Number
31/2025
Publication Type
INA
Invention Field
BIOTECHNOLOGY
Status
Email
Parent Application
Applicants
ELI LILLY AND COMPANY
Lilly Corporate Center
Indianapolis, Indiana 46285
Inventors
1. GARG, Ashish
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
2. KAUR, Amritpreet
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
3. KREGE, John Henry
c/o ELI LILLY AND COMPANYP.O. Box 6288Indianapolis, Indiana 46206-6288
4. MA, Xiaosu
c/o ELI LILLY AND COMPANYP.O. Box 6288Indianapolis, Indiana 46206-6288
5. NI, Wei
c/o ELI LILLY AND COMPANYP.O. Box 6288Indianapolis, Indiana 46206-6288
6. HAW, Helle Linnebjerg
c/o ELI LILLY AND COMPANYP.O. Box 6288Indianapolis, Indiana 46206-6288
Specification
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 202517066465-STATEMENT OF UNDERTAKING (FORM 3) [11-07-2025(online)].pdf | 2025-07-11 |
| 3 | 202517066465-Sequence Listing in PDF [11-07-2025(online)].pdf | 2025-07-11 |
| 4 | 202517066465-PRIORITY DOCUMENTS [11-07-2025(online)].pdf | 2025-07-11 |
| 5 | 202517066465-NOTIFICATION OF INT. APPLN. NO. & FILING DATE (PCT-RO-105-PCT Pamphlet) [11-07-2025(online)].pdf | 2025-07-11 |
| 6 | 202517066465-MARKED COPIES OF AMENDEMENTS [11-07-2025(online)].pdf | 2025-07-11 |
| 7 | 202517066465-FORM 18 [11-07-2025(online)].pdf | 2025-07-11 |
| 8 | 202517066465-FORM 13 [11-07-2025(online)].pdf | 2025-07-11 |
| 9 | 202517066465-FORM 1 [11-07-2025(online)].pdf | 2025-07-11 |
| 10 | 202517066465-FIGURE OF ABSTRACT [11-07-2025(online)].pdf | 2025-07-11 |
| 11 | 202517066465-DECLARATION OF INVENTORSHIP (FORM 5) [11-07-2025(online)].pdf | 2025-07-11 |
| 12 | 202517066465-COMPLETE SPECIFICATION [11-07-2025(online)].pdf | 2025-07-11 |
| 13 | 202517066465-CLAIMS UNDER RULE 1 (PROVISIO) OF RULE 20 [11-07-2025(online)].pdf | 2025-07-11 |
| 14 | 202517066465-AMMENDED DOCUMENTS [11-07-2025(online)].pdf | 2025-07-11 |
| 15 | 202517066465-Proof of Right [22-07-2025(online)].pdf | 2025-07-22 |
| 16 | 202517066465-FORM-26 [22-07-2025(online)].pdf | 2025-07-22 |