Sign In to Follow Application
View All Documents & Correspondence
View All Documents & Correspondence
Novel Rna Therapeutics And Uses Thereof
Abstract: The present disclosure relates to novel therapeutic compounds, known as RNAi agents, that decrease expression of the HMGCR receptor (expressed by the HMGCR gene), thereby decreasing expression of mRNA and protein expression. Such RNAi agents are useful in the treatment of diseases and disorders involving the regulation of HMGCR expression and function, such as diseases and disorders that are risk factors for ASCVD (such as, dyslipidemia, such as hypercholesteremia).
Get Free WhatsApp Updates!
Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
15 July 2025
Publication Number
30/2025
Publication Type
INA
Invention Field
BIOTECHNOLOGY
Status
Email
Parent Application
Applicants
ELI LILLY AND COMPANY
Lilly Corporate Center
Indianapolis, Indiana 46285
Inventors
1. ANTONELLIS, Patrick Joseph
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
2. BEYER, Thomas Patrick
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
3. BRANTTIE, Jean Mawuena
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
4. CHENG, Christine Chih-Tao
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
5. DEBETS, Marjoke F.
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
6. GAVARDINAS, Konstantinos
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
7. LACKNER, Gregory Lawrence
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
8. WANG, Jibo
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
9. WILSON, Takako
c/o ELI LILLY AND COMPANY
P.O. Box 6288
Indianapolis, Indiana 46206-6288
Specification
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 202517067567-STATEMENT OF UNDERTAKING (FORM 3) [15-07-2025(online)].pdf | 2025-07-15 |
| 2 | 202517067567-Sequence Listing in PDF [15-07-2025(online)].pdf | 2025-07-15 |
| 3 | 202517067567-REQUEST FOR EXAMINATION (FORM-18) [15-07-2025(online)].pdf | 2025-07-15 |
| 4 | 202517067567-POWER OF AUTHORITY [15-07-2025(online)].pdf | 2025-07-15 |
| 5 | 202517067567-FORM 18 [15-07-2025(online)].pdf | 2025-07-15 |
| 6 | 202517067567-FORM 1 [15-07-2025(online)].pdf | 2025-07-15 |
| 7 | 202517067567-DECLARATION OF INVENTORSHIP (FORM 5) [15-07-2025(online)].pdf | 2025-07-15 |
| 8 | 202517067567-COMPLETE SPECIFICATION [15-07-2025(online)].pdf | 2025-07-15 |