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Azepino[4,5 B]Indolone Cgas Inhibitors
Abstract: The present invention relates to novel cGAS inhibitor compounds, having a formula of (IIa) to pharmaceutical compositions comprising the compounds, and to methods of using the compounds and compositions to treat certain pathological conditions such as immune-mediated diseases.
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
18 July 2025
Publication Number
33/2025
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
Parent Application
Applicants
ELI LILLY AND COMPANY
Lilly Corporate Center
Indianapolis, Indiana 46285
Inventors
1. AGEJAS CHICHARRO, Francisco Javier
c/o Eli Lilly and Company
P.O. Box 6288
Indianapolis, Indiana 46206-6288
2. AHMED, Adel
c/o Eli Lilly and Company
P.O. Box 6288
Indianapolis, Indiana 46206-6288
3. CARSON, Cheryl Ann
c/o Eli Lilly and Company
P.O. Box 6288
Indianapolis, Indiana 46206-6288
4. CONNER, Scott Eugene
c/o Eli Lilly and Company
P.O. Box 6288
Indianapolis, Indiana 46206-6288
5. CUMMING, Graham Robert
c/o Eli Lilly and Company
P.O. Box 6288
Indianapolis, Indiana 46206-6288
6. FORTNER, Kevin Charles
c/o Eli Lilly and Company
P.O. Box 6288
Indianapolis, Indiana 46206-6288
7. GERNERT, Douglas L.
c/o Eli Lilly and Company
P.O. Box 6288
Indianapolis, Indiana 46206-6288
8. GREEN, Steven J.
c/o Eli Lilly and Company
P.O. Box 6288
Indianapolis, Indiana 46206-6288
9. LUGAR, Charles W.
c/o Eli Lilly and Company
P.O. Box 6288
Indianapolis, Indiana 46206-6288
10. MARIMUTHU, Jothirajah
c/o Eli Lilly and Company
P.O. Box 6288
Indianapolis, Indiana 46206-6288
11. MARTINEZ BROKAW, Christina
c/o Eli Lilly and Company
P.O. Box 6288
Indianapolis, Indiana 46206-6288
12. NAGARAJAN, Shanthi
c/o Eli Lilly and Company
P.O. Box 6288
Indianapolis, Indiana 46206-6288
13. ONOBUN, Emmanuel
c/o Eli Lilly and Company
P.O. Box 6288
Indianapolis, Indiana 46206-6288
14. TROMICZAK, Eric George
c/o Eli Lilly and Company
P.O. Box 6288
Indianapolis, Indiana 46206-6288
15. VARIN, Thibault Francois
c/o Eli Lilly and Company
P.O. Box 6288
Indianapolis, Indiana 46206-6288
Specification
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 202517068767-STATEMENT OF UNDERTAKING (FORM 3) [18-07-2025(online)].pdf | 2025-07-18 |
| 2 | 202517068767-REQUEST FOR EXAMINATION (FORM-18) [18-07-2025(online)].pdf | 2025-07-18 |
| 3 | 202517068767-PRIORITY DOCUMENTS [18-07-2025(online)].pdf | 2025-07-18 |
| 4 | 202517068767-NOTIFICATION OF INT. APPLN. NO. & FILING DATE (PCT-RO-105-PCT Pamphlet) [18-07-2025(online)].pdf | 2025-07-18 |
| 5 | 202517068767-FORM-26 [18-07-2025(online)].pdf | 2025-07-18 |
| 6 | 202517068767-FORM 18 [18-07-2025(online)].pdf | 2025-07-18 |
| 7 | 202517068767-FORM 1 [18-07-2025(online)].pdf | 2025-07-18 |
| 8 | 202517068767-DECLARATION OF INVENTORSHIP (FORM 5) [18-07-2025(online)].pdf | 2025-07-18 |
| 9 | 202517068767-COMPLETE SPECIFICATION [18-07-2025(online)].pdf | 2025-07-18 |
| 10 | 202517068767-FORM 3 [06-11-2025(online)].pdf | 2025-11-06 |