Kras Inhibitors

Abstract: The present invention provides compounds of the formula (I) wherein A, Z, G, R1, R2, and R4 are as described herein, pharmaceutically acceptable salts thereof, and methods of using these compounds and pharmaceutically acceptable salts thereof for treating patients for cancer.

Patent Information

Application #

Filing Date

06 August 2025

Publication Number

41/2025

Publication Type

INA

Invention Field

CHEMICAL

Status

Email

Parent Application

Applicants

ELI LILLY AND COMPANY

Lilly Corporate Center Indianapolis, Indiana 46285

Inventors

1. ABRAHAM, Adedoyin David

c/o Eli Lilly and Company P. O. Box 6288 Indianapolis, Indiana 46206-6288

2. VALERO DE LA CRUZ, Alberto

c/o Eli Lilly and CompanyP. O. Box 6288Indianapolis, Indiana 46206-6288

3. DILGER, Andrew

c/o Eli Lilly and Company P. O. Box 6288 Indianapolis, Indiana 46206-6288

4. BUME, Desta

c/o Eli Lilly and Company P. O. Box 6288 Indianapolis, Indiana 46206-6288

5. PRIEGO SOLER, Julián

c/o Eli Lilly and CompanyP. O. Box 6288Indianapolis, Indiana 46206-6288

6. PRIETO VALLEJO, Maria Lourdes

c/o Eli Lilly and CompanyP. O. Box 6288Indianapolis, Indiana 46206-6288

7. BARBERIS, Mario

c/o Eli Lilly and CompanyP. O. Box 6288Indianapolis, Indiana 46206-6288

8. GARZÓN SANZ, Miguel

c/o Eli Lilly and CompanyP. O. Box 6288Indianapolis, Indiana 46206-6288

9. RAJAMANI, Ramkumar

c/o Eli Lilly and Company P. O. Box 6288 Indianapolis, Indiana 46206-6288

10. ARONOW, Sean

c/o Eli Lilly and Company P. O. Box 6288 Indianapolis, Indiana 46206-6288

11. WALLS, Shane Michael

Eli Lilly and Company P. O. Box 6288 Indianapolis, Indiana 46206-6288

12. GUTIERREZ SANFELICIANO, Sonia Maria

c/o Eli Lilly and CompanyP. O. Box 6288Indianapolis, Indiana 46206-6288

13. KERCHER, Timothy Scott

c/o Eli Lilly and Company P. O. Box 6288 Indianapolis, Indiana 46206-6288

14. MOLERO FLÓREZ, Victoriano

c/o Eli Lilly and CompanyP. O. Box 6288Indianapolis, Indiana 46206-6288

15. CHEN, Xiaohong

c/o Eli Lilly and Company P. O. Box 6288 Indianapolis, Indiana 46206-6288

Specification

Documents

Application Documents

#	Name	Date
1	202517074739-STATEMENT OF UNDERTAKING (FORM 3) [06-08-2025(online)].pdf	2025-08-06
2	202517074739-REQUEST FOR EXAMINATION (FORM-18) [06-08-2025(online)].pdf	2025-08-06
3	202517074739-PRIORITY DOCUMENTS [06-08-2025(online)].pdf	2025-08-06
4	202517074739-POWER OF AUTHORITY [06-08-2025(online)].pdf	2025-08-06
5	202517074739-FORM 18 [06-08-2025(online)].pdf	2025-08-06
6	202517074739-FORM 1 [06-08-2025(online)].pdf	2025-08-06
7	202517074739-DECLARATION OF INVENTORSHIP (FORM 5) [06-08-2025(online)].pdf	2025-08-06
8	202517074739-COMPLETE SPECIFICATION [06-08-2025(online)].pdf	2025-08-06
9	202517074739-CLAIMS UNDER RULE 1 (PROVISIO) OF RULE 20 [06-08-2025(online)].pdf	2025-08-06
10	202517074739-Proof of Right [12-08-2025(online)].pdf	2025-08-12