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Kras Inhibitors
Abstract: The present invention provides compounds of the formula I wherein A, Z, G, R1, R2, and R4 are as described herein, pharmaceutically acceptable salts thereof, and methods of using these compounds and pharmaceutically acceptable salts thereof for treating patients for cancer.
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
30 September 2025
Publication Number
44/2025
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
Parent Application
Applicants
ELI LILLY AND COMPANY
Lilly Corporate Center
Indianapolis, Indiana 46285
Inventors
1. ABRAHAM, Adedoyin David
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
2. VALERO DE LA CRUZ, Alberto
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
3. MARCOS LLORENTE, Alicia
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
4. ENRIQUEZ GARCIA, Alvaro
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
5. DILGER, Andrew
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
6. GUO, Deqi
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
7. BUME, Desta
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
8. LAURENT CORDIER, Frederic
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
9. ZHAO, Gaiying
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
10. ROJO GARCIA, Isabel
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
11. HENRY, James Robert
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
12. LAMAR, Jason Eric
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
13. BASTIAN, Jolie Anne
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
14. RINCON CABEZUDO, Juan Antonio
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
15. PRIEGO SOLER, Julián
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
16. PRIETO VALLEJO, Maria Lourdes
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
17. BARBERIS, Mario
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
18. GARZÓN SANZ, Miguel
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
19. BAUMGARTNER, Matthew Patrick
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
20. GARCIA LOSADA, Pablo
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
21. RAJAMANI, Ramkumar
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
22. JOHNSTON, Richard Duane
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
23. HAZLITT, Robert
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
24. CARBALLARES MARTIN, Santiago
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
25. ARONOW, Sean
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
26. WALLS, Shane Michael
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
27. GUTIERREZ SANFELICIANO, Sonia Maria
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
28. ANDREWS, Steven
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
29. KERCHER, Timothy Scott
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
30. MOLERO FLÓREZ, Victoriano
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
31. LUMERAS AMADOR, Wenceslao
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
32. SCAGGS, William Rush
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
33. CHEN, Xiaohong
c/o Eli Lilly and Company
P. O. Box 6288
Indianapolis, Indiana 46206-6288
Specification
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 202517094266-STATEMENT OF UNDERTAKING (FORM 3) [30-09-2025(online)].pdf | 2025-09-30 |
| 2 | 202517094266-REQUEST FOR EXAMINATION (FORM-18) [30-09-2025(online)].pdf | 2025-09-30 |
| 3 | 202517094266-PRIORITY DOCUMENTS [30-09-2025(online)].pdf | 2025-09-30 |
| 4 | 202517094266-POWER OF AUTHORITY [30-09-2025(online)].pdf | 2025-09-30 |
| 5 | 202517094266-NOTIFICATION OF INT. APPLN. NO. & FILING DATE (PCT-RO-105-PCT Pamphlet) [30-09-2025(online)].pdf | 2025-09-30 |
| 6 | 202517094266-FORM 18 [30-09-2025(online)].pdf | 2025-09-30 |
| 7 | 202517094266-FORM 1 [30-09-2025(online)].pdf | 2025-09-30 |
| 8 | 202517094266-DECLARATION OF INVENTORSHIP (FORM 5) [30-09-2025(online)].pdf | 2025-09-30 |
| 9 | 202517094266-COMPLETE SPECIFICATION [30-09-2025(online)].pdf | 2025-09-30 |
| 10 | 202517094266-MARKED COPIES OF AMENDEMENTS [01-10-2025(online)].pdf | 2025-10-01 |
| 11 | 202517094266-FORM 13 [01-10-2025(online)].pdf | 2025-10-01 |
| 12 | 202517094266-Annexure [01-10-2025(online)].pdf | 2025-10-01 |
| 13 | 202517094266-AMMENDED DOCUMENTS [01-10-2025(online)].pdf | 2025-10-01 |
| 14 | 202517094266-Proof of Right [03-11-2025(online)].pdf | 2025-11-03 |