Description:A] Technical Field of the Invention:
[001] The proposed invention generally relates to a method of preparation of intermediates of general formula (I)

Where R1 = H, CN, Br, Cl
R2 = CH3, H, Cl
More particularly, the present invention relates to method of preparation of formula (II) i.e., and formula (III) i.e., .
B] Background:
[002] Organic compounds belonging to athranilamide / diamide groups have long been used as very effective and selective insecticides and their demand is growing day by day.
[003] With shrinking farming land and growing demand for agricultural produce coupled with the increasing population, there is tremendous pressure to increase agricultural yield. A solution is to reduce crop loss due to seasonal pests with proper treatment and less use of more effective crop care products.
[004] Some actives in such products include Cyantraniliprole, Chlorantraniliprole, Tetraniliprole, Tetrachloroanthraniliprole, et cetera. These molecules are effective against pests upon direct ingestion and by contact as well. Their low mammalian toxicity makes them more useful.

[005] With an increase in the use of products containing these actives, a cost-effective and simple process for their production is desired.
[006] The process disclosed in the present disclosure provides a very simple, environmentally friendly and cost-effective method to produce the key intermediates of these products.
[007] There are several disclosures, patent literature and non-patent literature that provide for methods of various synthetic steps for final preparation of target intermediate of formula (I). Few of them are mentioned herewith.
a. “Organic Synthesis (2001) has reported nucleophilic substitution of aromatic bromide with NaCN in the presence of N,N-Dimethyl ethylenediamine, KI and cuprous iodide.

b. “Bioorganic and Medicinal Chemistry Letters (2005) 15 (7), pages 1841-1845” describes nucleophilic substitution of bromide with KCN in the presence of a catalyst N,N-dimethyl ethylenediamine, dimethyl acetal, cuprous iodide on the following scheme.

c. WO2008082502 describes a process for preparation of 2-Amino-5-Cyanobenzamides from the corresponding-5-halo compounds using metal cyanides in the presence of cuprous iodide and N,N Dimethyl ethylenediamine as catalyst.

d. WO2006062978A1 discloses a process for the preparation of 2-Amino-5-cyano-N,3-dimethylbenzamide by reacting an isatoic anhydride derivative with aqueous methylamine and subsequent bromination and cyanation as given below.

e. WO2012103436 discloses a process for the preparation of 2-Amino-5-cyano-N,3-dimethylbenzamide by reacting 2-Amino-3-methyl-5-cyano bromo benzene with carbon monoxide and methylamine in the presence of Pd (acac)2 catalyst.

f. WO2009/111553 Describes the preparation of compound (V) from (IV) by using a metal cyanide in presence of copper containing catalyst.

Where A1 = -NH-CH3 , -NH-C2H5, -OCH3, -OC2H5, et cetera
A2 = Cl, CH3
X = Cl, Br
g. Preparation of said benzamide derivatives are also described in the following literature among others:
WO2008/08252, WO2009/085816, WO2009/006061, WO2009/061991, WO2009/111553, WO2008/070158, WO2008/082502 with varying yields and purity.
[008] However, there is still a need for a process that is quicker, more cost effective and requires less frequent isolation of the intermediates throughout the process. The present invention aims to address those issues in the description mentioned below.

C] Objects of the Invention:
[009] The primary object of the present invention is to provide a simple, cost-effective, and efficient process for the preparation of intermediate having formula (I), i.e., wherein R1 = H, CN, Br, Cl and R2 = CH3, H, Cl
[010] Another object of the present invention is to provide a method of synthesis of 2-Amino-5-Cyano-N,3-dimethyl-benzamide of formula (II) represented as and 2-Amino-3,5-dichloro-N-methyl benzamide of formula (III) represented as and other related intermediates.
[011] Yet another object of the present invention is to achieve process optimization and efficiency
to develop an optimized synthetic process that allows in-situ reactions for multiple steps, minimizing isolation and purification steps, thereby improving reaction efficiency.
and to reduce reaction times and energy consumption by avoiding unnecessary work-up and purification steps.
[012] Yet another objective of the present invention is to have a product with higher yield and purity by selecting suitable catalysts, solvents, and reagents and to minimize side reactions and impurity formation, ensuring that the final product meets industrial quality standards.
[013] Yet another objective of the present invention is to have a product that is cost effective and scalable by using easily available starting materials such as 2-Nitro-3-methyl benzoic acid and to ensure that the process is suitable for large-scale industrial production with minimal operational costs.
[014] Yet another objective of the present invention is to have a method that reduces use of hazardous reagents and ensure safer handling. Hazardous reagents, such as gaseous hydrogen and toxic Cyanation agents like NaCN and KCN are replaced with safer alternatives like Hydrazine Hydrate for Hydrogenation and Acetone Cyanohydrin for Cyanation and to improve the safety profile of the manufacturing process by eliminating the need for flammable or highly reactive reagents.
[015] Yet another objective of the present invention is to develop a selective chlorination process using Sulfuryl chloride (SO2Cl2) for preparing 2-Amino-5-Chloro-N,3-dimethyl benzamide with high specificity and minimal by-products and to establish an effective bromination process using molecular bromine or alternative brominating agents to yield 2-Amino-5-Bromo-N,3-dimethylbenzamide.
[016] Yet another objective of the present invention is to have environmental benefits and sustainability and to reduce solvent waste and the environmental impact of the process by reusing reaction media where possible.
[017] Yet another objective of the present invention is to develop a greener synthetic route with minimal hazardous waste generation, contributing to sustainable industrial practices.
[018] By achieving these objectives, the present invention presents a significant advancement in the field of chemical synthesis, particularly in the preparation of critical intermediates for high-value industrial applications.

D] Summary of the Invention:
[019] The various embodiments of the present invention provide for a simple, cost-effective, and efficient method for preparation of of intermediate having formula (I), i.e., wherein R1 = H, CN, Br, Cl and R2 = CH3, H, Cl.
[020] The primary embodiment of the present invention is to provide a simple and cost-effective process for preparation of 2-Amino-5-Cyano-N,3-dimethyl-benzamide of formula (II)

[021] According to another embodiment of the present invention, the process involves esterification of 2-Nitro-3-methyl benzoic acid using an excess of methanol or ethanol in the presence of an acidic catalyst to obtain the corresponding ester, which is further reacted with gaseous methylamine in situ to produce 2-Nitro-N,3-dimethylbenzamide.

[022] According to yet another embodiment of the present invention, the resulting compound that is 2-Nitro-N,3-dimethyl benzamide is then directly reacted with Hydrazine Hydrate in the same alcoholic medium without isolation of the product to get 2-Amino -N,3-dimethyl benzamide as given below:

[023] According to yet another embodiment of the present invention, 2-Amino-N,3-dimethyl benzamide is selectively chlorinated by using Sulfuryl chloride to produce 2-Amino-5-Chloro-N,3-dimethyl benzamide

[024] According to yet another embodiment of the present invention, the compound 2-Amino-N,3-dimethylbenzamide is brominated by conventional methods to get 2-Amino-5-bromo-N,3-dimethylbenzamide as given below:

[025] According to yet another embodiment of the present invention, the resulting 2-Amino-5-Bromo-N,3-dimethylbenzamide is then reacted with Acetone Cyanohydrin for Cyanation at the presence of suitable catalyst to produce 2-Amino-5-Cyano-N,3-dimethylbenzamide which is an advanced intermediate for Cyantraniliprole, Tetraniliprole, et cetera.

[026] According to yet another embodiment of the present invention, a process for producing 2-Amino-3,5-dichloro-N,3-methyl benzamide of formula (III) by the following procedure

[027] According to yet another embodiment of the present invention, 2-Nitro benzoic acid is esterified in excess primary alcohol like methanol/ethanol and subsequently reacted with gaseous MeNH2 in the same alcoholic medium to get 2-Nitro-N-methyl benzamide

[028] According to yet another embodiment of the present invention, 2-Nitro-N-methylbenzamide is then directly reacted with Hydrazine Hydrate in situ in the methanol or ethanol in presence of a Catalyst resulting in 2- Amino-N-methyl benzamide as shown in the reaction below:

[029] According to yet another embodiment of the present invention, the 2-Amino-N -methyl benzamide is reacted with a Chlorinating agent Sulfuryl chloride to get directly 2-Amino-3,5 Dichloro-N-methyl benzamide resulting in an advanced intermediate for Tetrachloroantraniliprole.

E] Brief description of the Invention:
[030] The present invention relates to a novel and cost-effective process for synthesizing 2-Amino-5-Cyano-N,3-dimethyl-benzamide and other related intermediates, which serve as key building blocks in the production of advanced agrochemical and pharmaceutical compounds.
[031] The invention simplifies conventional multi-step processes by enabling in-situ reactions, reducing solvent usage, minimizing waste generation, and enhancing overall efficiency.
[032] By streamlining reaction steps and avoiding the need for intermediate isolation, the process significantly reduces production time, cost, and environmental impact, making it highly suitable for commercial-scale manufacturing.
[033] Additionally, the use of safer reagents and alternative Cyanating agents improves operational safety and sustainability while maintaining high product yields and purity.

F] Detailed Description
[034] In the following detailed description, a reference is made to the accompanying chemical reactions that form a part hereof, and in which the specific embodiments that may be practiced is shown by way of illustration(s). The embodiments are described in sufficient detail to enable those skilled in the art to practice the embodiments and it is to be understood that the logical, mechanical and other changes may be made without departing from the scope of the embodiments. The following detailed description is therefore not to be taken in a limiting sense.
[035] Various embodiments of the present invention disclose a method for producing chemical intermediate under the formula (I) represented herein below:

wherein R1 = H, CN, Br, Cl and R2 = CH3, H, Cl.
[036] The present invention provides for a method of synthesizing 2-Amino-5-Chloro -N,3-dimethyl benzamide of formula (VI) through a series of efficient and cost-effective reaction steps:

[037] Esterification: The method begins with a 2-Nitro-3-methyl benzoic acid which is very cheap and easily available is taken in a primary Alcohol like Methanol / Ethanol for a simple esterification process. – forms part of the prior art. No novelty or inventive step here.

2-Nitro -3-methylbenzoic acid is dissolved in excess methanol and refluxed at its boiling point in presence of a suitable acidic catalyst (PTSA/ H2SO4 etc.) for 3-4 hours. This provides the corresponding methyl ester of this compound.
Alternately Ethanol can be used to produce the corresponding ethyl ester instead of Methyl ester.
[038] Amidation: Optionally this esterification reaction can be conducted in the presence of any suitable solvent along with alcohol however - preferably excess alcohol is used for full conversion. After complete esterification, the whole reaction mass is allowed to cool, and methyl amine is purged into the reaction. This reaction can be done at a temperature of 20-50°C, preferably at 30-40°C for 3-5 hours, preferably for 3-4 hours. Absorption of methylamine gas is almost quantitative. Completion of reaction leads to the formation of 2-Nitro-N,3-dimethyl benzamide. Methyl amine can be also used as a solution dissolved in the same alcohol used for this reaction. Both methyl and ethyl ester will provide the same result, and the end product will be the same for both cases.

[039] Hydrogenation: Resulting 2-Nitro-N,3-dimethyl benzamide is then directly taken for hydrogenation reaction in the same alcoholic solution without isolating the product with Hydrazine hydrate at the presence of a catalyst. Activated charcoal is found to be the most effective catalyst for this reaction and in the absence of it the reaction is very slow. During the reaction evolution of large quantity of Hydrogen gas may lead to some foam generation which may be removed by a defoamer. Generally, this reaction can be done from 30- 70°C, however more preferable temperature is 45-60°C. This reaction is very selective, and formation of impurity is almost negligible. Conversion of this reaction is also very good and altogether this is an excellent process for commercial scale. Another advantage of this process is that it does not require gaseous hydrogen. This reaction produces 2-Amino-N,3-dimethyl benzamide in excellent yield and quality.

[040] Methods under paragraphs [038] and [039] are carried out in-situ and does not require isolation at each step.

[041] The resulting compound 2-Amino-N,3-dimethyl benzamide is then isolated by solvent displacement with a suitable solvent for next chlorination step.
[042] A water immiscible chlorinated solvent is suitable for this reaction. Suitable solvents for this next chlorination in MDC/EDC or CHCl3, CCl3 et cetera.,
For chlorination of this product reported Chlorinating agents are SOCl2, POCl3, PCl5 or molecular chlorine, however we have found that SO2Cl2 is an excellent and most suitable reagent for this step. This is very selective and provides a high-quality target product of formula (IX) with an excellent yield.
• Time and temperature for Chlorination reaction with SO2Cl2 is 10 - 40°C, preferably 10-30°C for completion of this reaction. The reaction is slower at lower temperatures and does not proceed to completion. At higher temperatures, the reaction is faster, however, impurity formation may increase.
• The final chlorinated product remains as a hydrochloride salt which is then reacted with a base to get pure product in solid form preferably in aqueous medium. The final product is then filtered and dried at elevated temperature.

[043] The present invention also comprises a simple and cost-effective process for preparation of 2-Amino-5-Cyano-N,3-dimethylbenzamide (II)

[044] Same starting material which is easily available and cheap 2-Nitro-3-methyl benzoic acid can be converted to 2-Amino-N,3-dimethylbenzamide by previously described method in good yield and quality. This compound is then selectively brominated by using molecular bromine.
Alternately bromination can be done by using (HBr and H2O2 ) or N-Bromo-succinimide et cetera to get compound of formula (VII).

[045] This Bromo compound is then reacted with Acetone cyanohydrin or any known compound used for Cyanation eg. CuCN, or ferricyanide compound to produce 5-Cyano-2-Amino-N,3-dimethyl benzamide (II) which is used for manufacturing Tetraniliprole or Cyantraniliprole.

[046] It has also been observed that that Acetone cyanohydrin can substitute hazardous Cyanating agents like NaCN , KCN , CuCN et cetera. The presence on copper catalyst with a chelating agent and iodide salt is required. Diisopropylamine can also be used along with acetone cyanohydrin for completion of this reaction.

[047] Moreover, Acetone cyanohydrin is easily available and since it is a liquid, handling of this is much safer compared to NaCN / KCN or CuCN etc.

[048] Our proposed invention also describes preparation of 3,5-Dichloro-2-Amino-3-methylbenzamide (III).

The method of the reaction is similar as that of 2-Amino-N,3-dimethyl benzamide which has been described earlier. Esterification of 2-Nitro-3-Benzoic acid, is carried out with excess alcohol and directly reacted with methyl amine gas to produce 2-Nitro-N-methyl benzamide as per process described in detail earlier.

[049] Further, this compound can be reacted with Hydrazine hydrate directly in the same alcoholic medium to produce 2-Amino-N-methyl benzamide as given below in the reaction scheme.

[050] The molecule under formula (III) is then prepared by selective Chlorination with SO2Cl2 which provides a very efficient method for this process. It is found to be much better than conventional reagents like Cl2, HCl/H2O2, et cetera.

[051] The process for chlorination including the solvents, temperature conditions are similar to the description mentioned above. This intermediate is used for manufacturing of Tetrachloroantraniliprole.

[052] The following illustrations demonstrate our invention and should not be construed to limit the scope of our invention. Any person skilled in the art using the preceding description can utilize the present invention to its fullest extent.
Illustration No. 1
Preparation of 2- Amino-5-Chloro-N,3-Dimethyl benzamide
[053] 100 gm 2 Amino-N,3-Dimethyl benzamide (0.60 Mole) was dissolved in excess EDC (600 gm). Dimethyl formamide (3 gm, 0.041moles) was added & the mixture was cooled to 10-15°C. Sulfuryl chloride (128 g, 0.94 moles) was added dropwise and reaction was maintained for 1 h. Temperature was raised to 25-35°C and reaction was kept under maintaining for 2 h. Check HPLC for 92-93 % product formation; if not then again maintain for 2 h. After the reaction, 75 g of water was added dropwise. Maintain the mixture for 2 hours, then filter and dry the residue by suction. Material obtained has purity of 95–97%.
[054] Material obtained was dissolved in 500 g of distilled water. Cool the solution to 5–10°C. Add 95 g of 24% caustic lye (1.2 moles) dropwise until the pH reaches 9–10. Maintain the reaction for 2–3 hours. Filter the mixture and dry the residue by suction. Wash the residue with 300 g of distilled water and dry it again after filtration. 93 g of 99 % pure material was obtained (78% yield).

Illustration No. 2
Preparation of 2-Amino 5-Bromo -N,3-dimethyl benzamide.
[055] Take 100 g (0.608 moles) of 2-Amino-N,3-dimethyl benzamide and dissolve it in 200 g of acetic acid to form a clear solution. At a temperature of 25–30°C, begin the dropwise addition of a liquid bromine solution in acetic acid (comprising 100 g bromine and 25 g acetic acid) over 2 hours. After completing the addition, maintain the reaction mass at the same temperature for 3 hours. Check the HPLC purity, ensuring unreacted material below 0.5%.
[056] Add 400 g of water to the reaction mass and stir for 2 hours. Add 0.5 g of sodium thiosulfate to neutralize excess bromine. Adjust the pH of the reaction mass to 5.5–5.6 using 30% caustic lye and stir for an additional 2 hours. Filter the reaction mass completely and dry the residue by suction. Wash the wet cake with 300 g of DM water and dry it again. The dry product weighs 140 g with an HPLC purity of 99.5% and a yield of 95.9%.

Illustration No. 3
Preparation of 2-Amino–5-Cyano-N,3-dimethyl benzamide.
[057] Take 25 g (0.1 moles) of 2-Amino-5-Bromo-N,3-Dimethyl Benzamide, 3 g (0.015 moles) cuprous iodide, 12 g (0.07 moles) potassium iodide and 5 g (0.03 moles) 1,10-phenanthroline (phen) in a dry round bottom flask. The flask was then evacuated and back filled with nitrogen. Add anhydrous DMF (120 g) and heat the reaction to 110°C. After six hours, begin dropwise addition of 15 g (0.18 moles) acetone cyanohydrin and 24.6 g (0.17 moles) diisopropylethylamine (DIPEA). Maintain reaction till SM consumption (60 hours typically). Add extra acetone cyanohydrin and diisopropylethylamine if reaction seems to be stuck. Cool reaction to RT after SM consumption. Reaction is diluted with methyl tert-butyl ether (MTBE) and then filtered. Filtrate is washed with water and aqueous phase is extracted with MTBE. Organic layers were combined and distilled. Crude was treated with ethyl acetate and hexanes to give pure product with 40% yield.

Illustration No. 4A
Preparation of 2-Nitro 3-Methyl benzoic acid methyl ester
[058] Take 1000 g (5.51 moles) of 2-nitro-3-methylbenzoic acid (NMBA) and dissolve it in 1000 g (31.25 moles) of methanol to prepare a solution. Add 340g 98% sulfuric acid (3.47 moles) dropwise, maintaining the temperature at 35–40°C over 2–3 hours. After the addition, raise the temperature to 80–85°C and maintain it for 6–8 hours. Check the HPLC purity to ensure that unreacted NMBA is less than 0.5%. If these criteria are not met, maintain the reaction for an additional 2–3 hours.
[059] Quantify the methanolic solution and use it directly in the next step of the reaction. The HPLC purity of the methyl ester is more than 99%, with a yield of approximately 95%. Methanol can be partially removed before proceeding to the next step.

Illustration No. 4B
Preparation of 2-Nitro 3-methyl N,3-Dimethyl benzamide
[060] Take 1015 g (5.20 moles) of NMBA methyl ester along with 508 g of methanol as a solution from the previous step (Example 4A). Add 1472 g (14.22 moles) of 30% methanolic mono-methylamine solution to the mixture at a temperature of 25–30°C over 1 hour. Gradually raise the temperature to 30–35°C and maintain for 1 hour. Further raise the temperature to 35–45°C and maintain for an additional 2 hours.
[061] Check the HPLC purity, ensuring it reaches 99–99.6%. If the purity does not comply, maintain the reaction for an additional 2 hours. Take a sample from the reaction mass to check the yield and purity. Use the methanolic solution directly in the next hydrogenation step. The final product has an HPLC purity of 99.5% and a yield of 95%.

Illustration No. 4C
Preparation of 2 Amino-3-methyl- N,3 Dimethyl Benzamide
[062] Take 970 g (5.0 moles) of 2-Nitro-3-methyl-N,3-Dimethyl benzamide and dissolve it in 4850 g (151.5 moles) of methanol. Add 145.5 g (15%) of activated charcoal to the solution and heat the reaction mass to 45–50°C. Gradually add 1.5 moles of 100% hydrazine hydrate over 5–6 hours under controlled conditions. After the addition is complete, maintain the reaction mass at 60–62°C for 12–15 hours.
[063] Check the HPLC purity to ensure the desired product reaches 92–95%, with 5–6% of the corresponding acid also formed. Once the reaction is complete, filter the hot reaction mass through a Hyflow bed to remove the activated charcoal. Recover the methanol solvent completely and remove any residual traces by stripping. Add water to the reaction mass and wash the wet cake with a sodium bicarbonate solution to remove and recover the starting 2-Nitro-3-methyl benzoic acid, which can be recycled.
[064] Dry the final pure product at 60–65°C for 10–12 hours. The final yield is 80%, with an HPLC purity of >98.9%.

Illustration No. 5
Preparation of 2- Amino 3, 5-Dichloro N-methyl benzamide
[065] Take 100 g (0.73 moles) of 2-Amino-N-methyl benzamide and dissolve it in 8 times its weight of EDC. Add 3 g (0.041 moles) of dimethylformamide (DMF) to the solution and cool the reaction mass to 10–15°C. Gradually add 317 g (3.2 moles) of sulfuryl chloride under controlled conditions at 10–15°C. After completing the addition, maintain the reaction mass at this temperature for 1 hour, then gradually raise the temperature to 25–35°C and maintain it for another 2 hours.
[066] Check the HPLC purity to ensure it reaches 90–92%. If not, maintain the reaction for an additional 2 hours. Once the reaction is complete, slowly add 75 g of water and maintain the reaction mass for 2 hours. Filter the reaction mass and dry the wet cake by suction. The wet cake weighs 110–115 g with a purity of 90–92%, identified as 2-Amino-3,5-dichloro-N-methyl benzamide hydrochloride.
[067] Take 115 g of the wet material and mix it with 500 g of DM water. Cool the mixture to 5–10°C. Gradually add 95 g (1.2 moles) of 24% caustic lye dropwise until the pH reaches 9–10. Maintain the mixture for 2–3 hours, then filter and dry the residue by suction. Wash the material with 300 g of water and dry it again. The final material weighs 95 g with a purity of 98.0% and a yield of 63.5%.
[068] The best part of this invention is that in multiple steps you can go directly without isolation of the products, and this is a great advantage in the commercial scale. This will lead to reduction of time and consumption of Alcohol and saving of energy in the commercial plant.
, Claims:1. A method for preparation of the compound of formula

Where R1 = H, Cl, CN, Br
R2 = H, Cl. CH3, Br
Unless otherwise indicated when more than one substituent is present, each substitution is independent of other substituent in the said molecule.
Wherein the process for synthesizing 2-Amino-5-Cyano-N,3-dimethyl-benzamide comprising:
esterifying 2-Nitro-3-methyl benzoic acid with an excess of methanol or ethanol in the presence of an acidic catalyst under reflux conditions to produce the corresponding methyl or ethyl ester;
characterized in that
the methyl or ethyl ester is directly reacted with gaseous methylamine at 20-50°C to obtain 2-Nitro-N,3-dimethylbenzamide;
hydrogenating the 2-Nitro-N,3-dimethylbenzamide with Hydrazine Hydrate in the presence of activated charcoal as a catalyst at 30-70°C to obtain 2-Amino-N,3-dimethyl benzamide;
chlorinating 2-Amino-N,3-dimethyl benzamide using Sulfuryl chloride in a water-immiscible chlorinated solvent at 10-40°C to obtain 2-Amino-5-Chloro-N,3-dimethyl benzamide; and
reacting 2-Amino-5-Bromo-N,3-dimethylbenzamide with Acetone Cyanohydrin in the presence of a suitable catalyst to obtain 2-Amino-5-Cyano-N,3-dimethylbenzamide.
2. The process of claim 1, wherein the esterification reaction is conducted at reflux temperature for 3-4 hours.

3. The process of claim 1, wherein the methylamine is introduced as a gas or as a solution in the same alcohol used for esterification.

4. The process of claim 1, wherein the reduction with Hydrazine Hydrate occurs in situ without isolating the intermediate product.

5. The process of claim 1, wherein the chlorination in step (d) is carried out using Sulfuryl chloride (SO2Cl2) in a chlorinated solvent at 10-40°C, more particularly, between 25-35°C.

6. The process of claim 1, wherein the bromination in step (d) is conducted using a moiety from a group of molecular bromine, HBr/H2O2, N-Bromo-succinimide.

7. The process of claim 1, wherein the cyanation reaction in step (e) is carried out in the presence of diisopropylamine.

8. A process for synthesizing 2-Amino-3,5-Dichloro-N,3-methyl benzamide, comprising:
(a) Esterifying 2-Nitro benzoic acid with methanol or ethanol in the presence of an acidic catalyst to form an ester;
(b) Reacting the obtained ester with gaseous methylamine to yield 2-Nitro-N-methyl benzamide;
(c) Reducing the 2-Nitro-N-methyl benzamide with Hydrazine Hydrate in the presence of a catalyst to obtain 2-Amino-N-methyl benzamide;
(d) Chlorinating the 2-Amino-N-methyl benzamide using Sulfuryl chloride (SO2Cl2) to form 2-Amino-3,5-Dichloro-N-methyl benzamide.

9. The process of claim 8, wherein the chlorination reaction is performed in a chlorinated solvent selected from methylene dichloride (MDC), ethylene dichloride (EDC), chloroform, or carbon tetrachloride.

10. The process of claim 8, wherein the reaction is carried out at a temperature between 10-40°C, more particularly, between 25-35°C.

11. The process of claim 8, wherein the final product is obtained as a hydrochloride salt and further neutralized with a base.

12. A method of manufacturing Cyantraniliprole or Tetraniliprole, comprising the synthesis of 2-Amino-5-Cyano-N,3-dimethylbenzamide as described in claim 1 and its subsequent conversion into the target compound.

13. The process of claim 1, wherein all reaction steps are conducted in situ without the need for intermediate isolation.

14. The process of claim 1, wherein the use of Acetone Cyanohydrin as a cyanating agent.