Field of the invention
The present invention relates to alternative smoking articles. More specifically the
present invention relates to inhalation device for active delivery.
5 Background and the prior art
Alternative to conventional smoking article, which does not involve combustion
process, such as vaping, heat-not-burn devices are treated as additional alternatives
over conventional smoking articles. Multiple attempts have been made globally to
10 offer the consumers with variety of choices with respect to such alternative smoking
articles. One such solution is delivering desired active through pressurized liquid,
popularly known as inhalers / inhalation devices / metered dose inhalers (MDIs /
pressurized metered dose inhalers (pMDIs)). However, there are certain problems
associated to such systems. Firstly, the device along with canister has to be
15 discarded once completely it is used. Secondly consumer needs to put more effort
to actuate the canister-based inhaler. Thirdly most of the inhalers are canister based,
which is limiting the design innovation in this space. Fourthly the device has a big
mouthpiece due to canister dimensions.
20 The known MDIs or pMDIs are configured to deliver the aerosol from the cartridge
to the mouthpiece involves at least an angle of 90° and above which does not
provide the desired sensorial effect to the user.
US9408987 discloses inhaler comprising a reservoir of an inhalable composition
25 with an outlet at one end through which the inhalable composition is discharged. A
non-metered breath-activated valve is provided between the one end and the
reservoir, the breath-activated valve comprising a flow path extending from the
reservoir to the outlet end. At least a portion of the flow path is a deformable tube.
A clamping member pinches the deformable tube closed when no suction force is
30 applied to the device and releases the tube to open the flow path when suction is
applied at the outlet, to provide uninterrupted flow from the reservoir to the outlet.
3
However, US’987 does not disclose push/press/slide actuation mechanism in its
device or refillable inhalation design. US’987 describes an inhaler comprising a
reservoir of an inhalable composition with an outlet at one end through which the
inhalable composition is discharged. A non-metered breath-activated valve is
5 provided between the one end and the reservoir, the breath-activated valve
comprising a flow path extending from the reservoir to the outlet end. US’987
employs the use of breath-activated valve for the operation of the device. The breath
actuation mechanism as per US’987 sometimes fails to actuate if sufficient pressure
is not applied while suction, also it is difficult to customize it as per the need of the
10 user.
ES2361156 discloses needle-less syringe or inhaler comprises a casing containing
a spring-loaded piston. This has an opening, through which a cartridge of drug with
integral diffuser head can be introduced, either directly into the operating position
15 or on to a sliding carriage which is then pushed to this position. ES2361156
however requires priming as mandatory before actuation which is energy
consuming. Further the device of ES‘156 cannot handle high pressure liquid.
Furthermore, the cartridge in ES'156 has to be replaced completely and does not
have refilling option.
20
IN220475 discloses inhaler for producing an inhalable aerosol of a powdered
medicament includes an aerosolizing device in the form of a cylindrical vortex
chamber. The vortex chamber has a tangential inlet port and an axial exit port. The
ratio of the diameter of the vortex chamber to the diameter of the exit port is
25 between 4 and 12. The length of the exit port is less than its diameter. The crosssection of the inlet port is rectangular and is defined at the bottom and at the radially
outermost edge by the walls of the vortex chamber. The cross-sectional area of the
inlet conduit, which supplies the medicament in a gas flow to the inlet port,
decreases in the direction towards the vortex chamber. The inlet conduit may be
30 curved. The inhaler is capable of repeatably producing an aerosol of a medicament
with a high proportion of particles in the range 1 to 3 microns, while using a
4
relatively small amount of energy.
IN'475 relates to dry powder formulation and not high-pressure liquids through their
exit orifices. There is no phase change at the exit port, since it supports only dry
5 powders. IN‘475 deals with an inhaler for producing an inhalable aerosol of a
similar powdered medicament and includes an aerosolizing device in the form of a
cylindrical vortex chamber. This makes the design complex.
US2006118107 discloses a system for delivering a pharmaceutical formulation to
10 a patient that includes a container having a pharmaceutical formulation including at
least one medicament present therein, a metering assembly in communication with
the container, and a tubular nozzle having an inlet configured in size to
communicate with the metering assembly, and an outlet for directing the
medicament to a patient. The tubular nozzle preferably has a defined length and a
15 longitudinal axis that is curvilinear through the defined length of the tubular nozzle.
US2006118107 discloses the flow of liquid is up-side down i.e., in the gravitational
direction. These types of traditional inhalers mandatorily require canister and
activating the canister requires more energy. Further canister always comes with a
20 nozzle part and for refilling requirements, it needs to be done only through
machines.
CN103079619 metered-dose inhaler includes at least one vessel and an actuator for
receiving the at least one vessel. The at least one vessel includes a first reservoir
25 containing a first formulation and a second reservoir containing a second
formulation. The metered-dose inhaler is actuable when the at least one vessel is
received by the actuator. IN CN’619 employs a very well-known generic stem valve
delivery mechanism which is also used for the available pressurized metered dose
inhalers (pMDI) devices commercially available in the market. The metered-dose
30 inhaler is configured to simultaneously deliver a first metered dose of the first
formulation and a second metered dose of the second formulation upon actuation.
5
It is a metered dose inhaler which requires canister with actuator and mouthpiece
with nozzle as two distinct separable assemblies which is a complex one to use and
requires more energy.
5 US2010212665 discloses an actuator for a metered dose inhaler containing a
liquefied propellant and a medicament, the actuator comprising: a nozzle block
having a fluid flow path extending therethrough, the fluid flow path defined by an
internal chamber having an inlet and an outlet; the outlet being defined in a portion
of the nozzle block and comprising an exit channel extending therethrough, wherein
10 the exit channel has a narrow portion wherein the diameter of the channel is 0.3 mm
or less, the narrow portion being 0.5 mm or less in length; and the narrow portion
optionally including a constriction having a diameter of less than 0.3 mm. This is
also a metered dose inhaler which requires canister with actuator and mouthpiece
with nozzle as two distinct separable assemblies which is a complex one to use and
15 requires more energy.
US20130199528 describes an electronic device wherein the delivery of
composition takes place because of the pressure generator which pushes the predetermined volume of liquid to heating chamber. It discloses an improved medicant
20 delivery system wherein the carrier for the medicant is a fluid that can be atomized
or vaporized by exposure to heat. The system provides for repeatable dose of
medicant, can be stored in any orientation, and/or has an ability to maximize energy
efficiency. However the device as described in US20130199528 uses heat to
atomize the liquid. Thus there is always a need to provide a device that does not
25 require additional component such as heating component.
US20110290249A1 discloses an aerosol generator device comprises an elongate
body with an interior passageway extending longitudinally to its mouth end. The
device receives an interchangeable, pressurised canister charged with a nicotine
30 containing liquid that is discharged in a metered dose on manual actuation of a
trigger that causes a valve in the canister to open and discharge through a discharge
6
tube. Inner and outer collar members releasably couple the canister with a bayonet
action. The trigger is rotatably mounted on the body about a trigger axis spaced
from and extending transversely of the longitudinal axis of the device, and has a
manually depressible surface portion under a flexible cover, and a camming surface
5 portion that drives a slidable nozzle member inwardly of the body to press the
discharge tube inwardly of the canister and the valve so as to form an aerosol from
the liquid released from the canister.
US20120090629A1 elongated body including a chamber for containing a medium
10 and an outlet through which the medium exits the device into an oral or nasal
opening. A dispensing system selectively places the chamber and the outlet in
communication, causing medium to flow out of the device.
Both US20110290249A1 and US20120090629A1 describes a canister based
15 manually operated device which are disadvantageous.
US20200282159A1 discloses inhaler comprising an inner housing (1) with a
pressurized reservoir of an inhalable composition. A breath operated valve (5) is
operable by a user inhaling on an inhaling end of the inhaler. A composition flow
20 path extends from the breath operated valve (5) to the inhaling end via which the
composition is dispensed when the breath operated valve is opened. The breath
operated valve (5) is biased closed by a biasing member contacting the breath
operated valve at one end. A bung (16) in the inner housing is positioned in an
opening in the inner housing to support the end of the biasing member (8) opposite
25 to the breath operated valve. A rigid outer housing (3) surrounds the inner housing
and supports the bung (16).
US20160050973A1 discloses method of assembling a tubular simulated cigarette,
the method comprising providing an elongate hollow housing having an inhaling
30 end and a refill end; inserting an outlet valve tube, a dip tube and a support from
the refill end so that the support supports the proximal end of the dip tube in the
7
housing; inserting a refill valve into the refill end and fixing it in place to form a
composition reservoir with the dip tube placing the reservoir in fluid
communication with an outlet orifice when the outlet valve tube is open; inserting
a valve element into a recess in the side of the housing so that the valve element is
5 positioned to selectively close the outlet valve tube; inserting a breath operated
valve actuation mechanism laterally into the recess; and applying a cover to the
recess.
US20200282159A1 and US20160050973A1 employs the use of non-metered
10 breath actuated valve to release the composition when inhaled. Breathe actuated
valves used in US20200282159A1 and US20160050973A1 are not consistent as it
is based on the inhalation force and sometimes it does not trigger and needs multiple
attempts to trigger it.
15 US20110168175A1 discloses an inhaler including a pre-inserted cartridge (100).
The cartridge contains liquid (103) which is preferably pressurized to a low
pressure. The cartridge is connected via an aerosol valve (106) with the inhaler. The
liquid is further pressurized by a pump (117) of the inhaler to a high pressure and
atomized. US20110168175A1 is a canister based design and used for non20 pressurized liquid formulations such as ethanol /water based formulations. Thus it
has the disadvantages associated with canister based inhalers.
US20200404963 discloses a base for an e-vaping device is configured to couple
with multiple cartridges configured to generate separate, respective dispersions.
25 The cartridges may include one or more atomizer assemblies or vaporizer
assemblies. The base may include multiple connectors electrically coupled to the
power supply. The connectors may be configured to couple multiple dispersion
generators to a power supply of the base. The base may include control circuitry
configured to independently control dispersion generation by dispersion generators
30 coupled to the base. The control circuitry may independently control dispersion
generation by the first and second cartridges based on cartridge information
8
accessed through at least one of the first and second connectors. The control
circuitry may control dispersion generation by controlling power supplied to the
dispersion generators. US20200404963 is related to complex electronic cigarette
not any mechanically actuated device.
5
Thus, there is a need to develop a device which is easy to operate, less complex and
refilling can be done manually.
Object of the invention
10
It is an object of the present invention to overcome the drawbacks of the prior art.
It is another object of the present invention to provide a device being filled with
propellant based actives to deliver a desired particle size, preferably in the range of
1-10µm, more preferably in the range of, 1-5 µm and most preferably in the range
15 of 1-3 µm.
It is a further object of the present invention to provide a device which upon
actuating, deliveries specific amount of any desired active dosage to consumers,
preferably in the range of 1-10mg, more preferably in the range of 1-5mg and most
20 preferably in the range of 1-3 mg.
Summary of the invention
According to another aspect of the present invention there is provided a device
25 comprising: a housing with a reservoir therein and a mouthpiece; wherein said
reservoir is adapted to hold a composition and comprises atleast one capillary tube;
said mouthpiece comprises atleast one orifice and a mouth end; an actuator means
provided on the housing and operatively connected to the capillary tube; said
capillary tube having at least one divergent release valve; such that the orifice and
the divergent release valve are at an angle between 0 to 750
30 ; and the orifice and the
9
capillary tube are operatively connected so as to release said composition upon
activation of said actuator means.
According to another aspect of the present invention there is provided a method of
5 release of a composition from the device of the present invention, said method
comprises actuating the actuator means to work on the capillary tube so as to release
the composition from the reservoir based upon the disposition of the orifice and the
mouth end depending upon the need for fast, slow or medium release of said
composition.
10
According to another aspect of the present invention there is provided a method of
refilling the composition in the device, said method comprising engaging the oneway inlet valve of the device with a one-way pin valve of an external refill canister,
such that engagement of said two valves results in flow of high pressure liquid from
15 the canister to the device due to pressure difference.
According to yet another aspect of the present invention there is provided use of the
device of the present invention, wherein on being actuated the actuator means works
on the capillary tube so as to release the composition from the reservoir based upon
20 the disposition of the orifice and the mouth end, depending upon the need for fast,
slow or medium release of said composition.
Brief description of accompanying figures:
25 Figure 1 illustrates the design of the pull/slide type device in accordance with the
present invention.
Figure 2 illustrates the design of the press type device in accordance with the present
invention.
Figure 3 illustrates the actuating mechanism of press type inhaler device
30 Figure 4 illustrates the device filling mechanism
Figure 5 illustrates the design of the divergent release valve
10
Figure 6 illustrates the device in accordance with the present invention.
Figure 7 (a) illustrates the possible angular projection between the orifice (6) and
divergent release valve (7). Figure 7 (b) illustrates the enlarged view towards the
mouth of the device showing clearly the axis of the divergent valve and axis of the
5 orifice.
Detailed Description of the invention
The present invention provides an inhalation device that overcome the above said
10 problems and allows consumer to reuse the Inhaler multiple times by refilling it.
The device for inhalation according to the present invention comprises: a housing
with a reservoir therein and a mouthpiece; wherein said reservoir is adapted to hold
a composition and comprises atleast one capillary tube; said mouthpiece comprises
atleast one orifice and a mouth end; an actuator means provided on the housing and
15 operatively connected to the capillary tube; said capillary tube having at least one
divergent release valve; such that the orifice and the divergent release valve are at
an angle between 0 to 750
, preferably between 00
to 600
and most preferably 00
to
150
; and the orifice and the capillary tube are operatively connected so as to release
said composition upon activation of said actuator means.
20
It has been found that when the composition flows through said capillary tube to
said mouthpiece, in an angle upon activation of said inhalation article the orifice is
in line with the axis of the valve outlet which results in less deposition of the
composition on the mouth piece path way. Further, as the angle increases
25 functionality still exists but the deposition of the composition on the mouth piece
path way increases.
The composition according to the present invention can be any inhalable
composition, such as ones based on HFA. Thus, the composition is a pressurized
30 liquid which is released as an aerosol upon activation of said actuator means.
Typically, the composition includes 0.01 to 0.20% by weight actives and 99.80-
11
99.09% by weight propellant. Preferably the propellant is HFA 134a (1,1,1,2-
Tetrafluoroethane (CAS no -811-97-2)), which is a pharma grade fluorochemical.
The actives according to the present invention can be alkaloids.
5 The device of the present invention has a smaller mouthpiece that helps in directing
the plume towards the effective delivery system hence can be a better means of
effective dosage.
The device of the present invention can be actuated preferably through pull or slide
10 (as shown in Figure 1) or press (as shown in Figure 2) or any suitable means.
The mouth piece design of the present invention has a unique design. Figure 5
shows the various plume velocities based on the orifice present at the exit region of
the mouthpiece. Plume is the column/space in air of one fluid moving through that
15 contains suspended particles generated by the source (e.g. HFA). Plume Velocity is
defined as the rate at which the suspended particles reach the buccal cavity of the
user. Further, fig 5 also explains the relation between the velocity of the highpressure liquid and the distance between aperture and the mouth end. If the distance
between aperture and the mouth end is more, the velocity would be less and if
20 distance between aperture and mouth end is less, the said velocity will be more.
Exit orifice reduces the speed of the jet allowing consumer to inhale the active
compound easily, and also improving deposition.
It is known that the rate at which plume hits buccal cavity has different impact on
25 the consumer and most importantly, they can be designed based on the
requirements. A low velocity provides better breathe synchronization, and
deposition aspects could be improved depending on breath synchronization.
30
12
A high velocity gives less mouth deposition compared to low velocity device, also
deposition aspect is moderate depending on breath synchronization.
5 A medium velocity on the other hand provides mouth deposition which is moderate
and so is breathe synchronization, and active deposition depends on breath
synchronization.
The present inventors have found that the device of the present invention is capable
10 for offering the plume velocities be it a low or medium or high which is seamless,
preferably the plume velocities in the range of 1-100m/s, more preferably 10-80m/s,
most preferably 20-40m/s.
The velocity reduction in the present invention depends on the exit diameter and
15 the distance to mouth end. The exit diameter is <1mm and preferably in the range
from 0.3mm to 0.8mm; while the distance to mouth end ranges from 0 mm to 20
mm. The device of the present invention can be filled with propellant based actives
to deliver a desired particle size, preferably in the range of 1-10 µm, more
preferably in the range of, 1-5 µm and most preferably in the range of 1-3 µm.
20
Upon actuating, device of the present invention deliveries specific amount of clean
actives / dosage to consumers, preferably in the range of 1-10 mg, more preferably
in the range of 1-5 mg and most preferably in the range of 1-3 mg.
25 Refilling in the present invention can be done through manually, without any
machine interventions which is mandatory in canister type inhalers known in the
art.
The present device integrates all of the major components like reservoir to hold the
30 high pressure liquid, mouthpiece, etc and can be operated seamlessly to deliver the
desired particle size.
13
Accordingly, to another embodiment of the present invention there is provided a
method of release of a composition from the device, said method comprises
actuating the actuator means to work on the capillary tube so as to release the
5 composition from the reservoir based upon the disposition of the orifice and the
mouth end depending upon the need for fast, slow or medium release of said
composition.
Accordingly, to yet another embodiment of the present invention there is provided
10 a method of refilling the composition in the device of the present invention, said
method comprising engaging the one-way inlet valve of the device with a one-way
pin valve of a refill canister, such that engagement of said two valves results in flow
of high pressure liquid from the canister to the device due to pressure difference.
15 Accordingly, to further embodiment of the present invention there is provided use
of the device, wherein on being actuated the actuator means works on the capillary
tube so as to release the composition from the reservoir based upon the disposition
of the orifice and the mouth end, depending upon the need for fast, slow or medium
release of said composition.
20
Detailed description of accompanying figures
Figure 1 shows the design of the pull/slide type inhaler device in accordance
with the present invention.
25
The pull / slide type of inhaler device essentially consists of Housing (1), Reservoir
(2) and a mouthpiece (3). The housing further comprises of at least one actuator
means (4). The mouthpiece (3) further comprises of at least one orifice (6). The
reservoir comprises of at least one capillary tube (5) – placed inside the device and
30 invisible from outside view.
14
Figure 2 shows the design of the press type inhaler device in accordance with
the present invention.
The press type of inhaler device essentially consists housing (1), Reservoir (2) and
5 a mouthpiece (3). The housing further comprises of at least one actuator (4) means.
The reservoir comprises of at least one capillary tube (5) – placed inside the device
and invisible from outside view. The mouthpiece further comprises of at least one
orifice (6).
10 Figure 3 shows the actuating mechanism of press type inhaler device in
accordance with the present invention.
Figure 3 shows one of the embodiments of the present invention with the device
and its actuating mechanism (4) which is typically based on press type of actuation.
15 This is essentially to lift the divergent release valve (7), so that the high-pressure
liquid stored in the reservoir, passes through capillary tube subsequently through
the divergent release valve (7) and finally exits through the orifice (6) at the mouth
piece.
20 Yet another embodiment the device also equipped with pull or sliding type of
actuating mechanism which helps in lifting the divergent release vale (7) uprightly,
so that the high-pressure liquid traverses all the way from the reservoir and exits
through the exit orifice (6) at the mouth piece (Figure 6).
25 It is also important to note that, the actuating mechanism can be through press or
sliding or pull or any other suitable means which fall under mechanical actuation.
Further, the actuation means may also be enabled through haptics (touch based),
biometric based, RFID based, QR scan code based, voice based or contact less
actuation through wireless interfaces for e.g. blue tooth and the like.
30
15
Figure 4 illustrates the device filling mechanism in accordance with the present
invention.
In one of the embodiments, the present invention provides a filling mechanism of
5 the present device. The housing accommodates the chamber which holds the highpressure liquid. Once it is consumed completely, the chamber can be refilled for
further inhalation purposes. At the bottom of the device there is a one-way valve
(8) provided to refill the liquid from the canister to the device as shown in Fig4.
10 During the refilling process high pressure liquid stored in canister (01) is held
upside down and device (02) is also held upside down. The device has a one-way
inlet valve and the canister has a one-way pin valve. When these two valves engage
high pressure liquid flows form canister to device due to pressure difference.
15 Figure 5 illustrates the design of the divergent release valve in accordance with
the present invention.
Figure 5 shows the various plume velocities based on the orifice present at the exit
region of the mouth end. Plume is the column/space in air of one fluid moving
20 through that contains suspended particles generated by the source (e.g. HFA).
Plume Velocity is defined as the rate at which the suspended particles reach the
buccal cavity of the user. Fig 5 explains the relation between the velocity of the
high-pressure liquid and the distance between aperture/orifice and the mouth end.
If the distance between orifice and the mouth end is more, the velocity will be less
25 and if distance between orifice and mouth end is less, velocity is more.
The distance/disposition between orifice and the mouth end can be fixed in a device
or can be manipulated by the end user. For the latter case there is provided another
actuating means for manipulating the distance/disposition between the orifice and
30 the mouth end depending upon the need for fast, slow or medium release of said
composition.
16
In Figure 5, the propellant is in liquid state inside the container and is maintained
at 4-5 bar pressure, when the propellant mixture passes through the orifice it
undergoes rapid expansion process, leading to abrupt drop in pressure, which
5 further leads to the atomization process to form aerosol.
The size and position of the orifice plays a crucial role in the quality of the aerosol
formation. There are three modes of orifice size and position as shown in Section
A-A, B-B, C-C of figure 5 (all dimension is in mm). The mean size of the orifice
10 diameter ranges from 0.3 – 1 mm. In Section C-C, the orifice is located close
towards the mouth end, which will deliver a high velocity jet ejecting from the
mouth end to the user. In Section A-A, orifice is located about 6 mm from the mouth
end and the aerosol generated is decelerated. In Section B-B the orifice is located
about 16 mm from the mouth end and the generated aerosol is decelerated further,
15 beyond this position the generated aerosol cannot reach the user due to
recondensation within the channel leading to losses.
Figure 6 illustrates the cross-sectional design of the present device
20 Working of the invention -High pressure liquid is filled into the device using the
valve (8) which is stored in the reservoir (2) and upon liftment of the lever/actuating
means (4) in the direction shown as per figure 6, liquid from reservoir (2) passes
through the capillary tube (5) and divergent release valve (7) and finally passes
through the valve (6) to the mouth end. The variants of the valve (6) are further
25 illustrated in figure 5. The most preferred angle between the orifice (6) and
divergent release valve (7) is 0˚ (only a straight line).
Figure 7 illustrates the possible angular projection(s) between the orifice (6)
and divergent release valve (7).
30
17
As illustrated in Figure 7 (a), the angle between the orifice (6) and divergent release
valve (7) can be +15˚ to -15˚ and/or it can also be titled to an extent of +75˚.
The orifice is with one axis and the divergent valve mentioned is a three5 dimensional structure with a two-dimensional axis which can be measured with a
reference axis of the orifice. Figure 7 (b) illustrates the enlarged view towards the
mouth of the device showing clearly the axis of the divergent valve (1) and axis of
the orifice (2).
10 The present invention is now being illustrated by way of non-limiting example.
Example 1
A composition comprising 0.20% by weight actives and 99.80% by weight
15 propellant is provided as a high-pressure liquid and was filled into the device (1)
using the valve (8), high pressure liquid is stored in the chamber (2) and upon
liftment of the lever (4) in the direction shown as per figure 6, liquid from reservoir
(2) passes through the capillary tube (5) and divergent release valve (7) and finally
passes through the valve (6) to the mouth end. When in use, the user receives a blast
20 of aerosol which contains actives. Furthermore, when user synchronizes their intake
with the push button, better deposition is achieved/experienced.
25
30
18
WE CLAIM:
1. A device comprising: a housing (1) with a reservoir (2) therein and a
5 mouthpiece (3); wherein
said reservoir (2) is adapted to hold a composition and comprises atleast one
capillary tube (5);
said mouthpiece (3) comprises atleast one orifice (6) and a mouth end;
an actuator means (4) provided on the housing (1) and operatively connected
10 to the capillary tube (5);
said capillary tube (5) is characterized in having at least one divergent
release valve (7);
such that the orifice (6) and the divergent release valve (7) are at an angle
between 0 to 750
; and
15 the orifice (6) and the capillary tube (5) are operatively connected so as to
release said composition upon activation of said actuator means.
2. The device as claimed in claim 1, wherein the orifice (6) and the divergent
release valve (7) are at an angle between 0 to 600
; preferably between 0 to
150
20 .
3. The device as claimed in claim 1, wherein said composition held in said
reservoir (2) comprises 0.01 to 0.20% by weight of actives and 99.80 to
99.09% by weight propellant.
25
4. The device as claimed in claim 1, wherein said composition is a pressurized
liquid which is released as an aerosol upon activation of said actuator means
(4).
30 5. The device as claimed in claim 1, wherein said actuator means (4) is selected
from pull or slide means or press means.
19
6. The device as claimed in claim 1, wherein said actuator means (4) is enabled
through haptics (touch based), biometric based, RFID based, QR scan code
based, voice based or contact less actuation through wireless interfaces.
5
7. The device as claimed in claim 1, wherein said device has a one-way pin
valve for refilling of said composition.
8. The device as claimed in claim 1, wherein said device provides a plume
10 velocity in the range of 1-100m/s, more preferably 10-80m/s, most
preferably 20-40m/s.
9. The device as claimed in claim 1, wherein said orifice (6) has an exit
diameter <1mm, preferably in the range from 0.3mm to 0.8mm.
15
10. The device as claimed in claim 1, wherein said distance of the orifice (6) to
the mouth end ranges from 0 mm to 20 mm.
11. The device as claimed in claim 1, wherein disposition of the orifice (6) and
20 the mouth end is configured to provide fast, slow or medium release of said
composition.
12. The device as claimed in claim 1, wherein said composition has a particle
size, preferably in the range of 1-10 µm, more preferably in the range of, 1-
25 5 µm and most preferably in the range of 1-3 µm.
13. The device as claimed in claim 1, wherein said device delivers actives, in
the range of 1-10 mg, more preferably in the range of 1-5 mg and most
preferably in the range of 1-3 mg.
30
14. A method of release of a composition from the device as claimed in any of
claims 1 to 13, said method comprises actuating the actuator means (4) to
20
work on the capillary tube (5) so as to release the composition from the
reservoir based upon the disposition of the orifice (6) and the mouth end,
depending upon the need for fast, slow or medium release of said
composition.
5
15. A method of refilling the composition in the device as claimed in any of
claims 1 to 13, said method comprising engaging the one-way inlet valve
(8) of the device with a one-way pin valve of an external refill canister, such
that engagement of said two valves results in flow of high pressure liquid
10 from the canister to the device due to pressure difference.
16. Use of the device as claimed in any of claims 1 to 13, wherein on being
actuated the actuator means (4) works on the capillary tube (5) so as to
release the composition from the reservoir based upon the disposition of the
15 orifice (6) and the mouth end, depending upon the need for fast, slow or
medium release of said composition.
Dated this 30th day of May 2025.
20
Dr. Sanchita Ganguli
Of S. MAJUMDAR & CO.
(Applicant’s Agent)
(Patent Agent No : IN/PA625)
25
30
35
21