Abstract: ABSTRACT POLYNUCLEOTIDE CONSTRUCTS, VECTORS, RECOMBINANT CELLS AND METHODS FOR HYDROXYLATING STEROIDS The present disclosure relates to polynucleotide constructs, vectors, recombinant bacterial cells and methods for hydroxylation of steroids. The recombinant bacterial cell, as disclosed, 5 expresses a heterologous bacterial CYP450 and redox partners, particularly ferredoxin reductase and ferredoxin for hydroxylating steroids, particularly at the challenging C14 position of the steroid. The present disclosure provides scalable, cost effective, and efficient production of C14 hydroxylated steroids. 10
Description:AS ATTACHED , Claims:AS ATTACHED
| # | Name | Date |
|---|---|---|
| 1 | 202541008438-STATEMENT OF UNDERTAKING (FORM 3) [31-01-2025(online)].pdf | 2025-01-31 |
| 3 | 202541008438-Sequence Listing in PDF [31-01-2025(online)].pdf | 2025-01-31 |
| 4 | 202541008438-REQUEST FOR EARLY PUBLICATION(FORM-9) [31-01-2025(online)].pdf | 2025-01-31 |
| 5 | 202541008438-POWER OF AUTHORITY [31-01-2025(online)].pdf | 2025-01-31 |
| 6 | 202541008438-FORM-9 [31-01-2025(online)].pdf | 2025-01-31 |
| 7 | 202541008438-FORM FOR SMALL ENTITY(FORM-28) [31-01-2025(online)].pdf | 2025-01-31 |
| 8 | 202541008438-FORM 1 [31-01-2025(online)].pdf | 2025-01-31 |
| 9 | 202541008438-EVIDENCE FOR REGISTRATION UNDER SSI(FORM-28) [31-01-2025(online)].pdf | 2025-01-31 |
| 10 | 202541008438-EDUCATIONAL INSTITUTION(S) [31-01-2025(online)].pdf | 2025-01-31 |
| 11 | 202541008438-DRAWINGS [31-01-2025(online)].pdf | 2025-01-31 |
| 12 | 202541008438-DECLARATION OF INVENTORSHIP (FORM 5) [31-01-2025(online)].pdf | 2025-01-31 |
| 13 | 202541008438-COMPLETE SPECIFICATION [31-01-2025(online)].pdf | 2025-01-31 |
| 14 | 202541008438-FORM 18A [04-02-2025(online)].pdf | 2025-02-04 |
| 15 | 202541008438-EVIDENCE OF ELIGIBILTY RULE 24C1f [04-02-2025(online)].pdf | 2025-02-04 |
| 16 | 202541008438-FORM-8 [11-02-2025(online)].pdf | 2025-02-11 |
| 17 | 202541008438-Proof of Right [17-02-2025(online)].pdf | 2025-02-17 |
| 18 | 202541008438-FER.pdf | 2025-11-18 |
| 1 | 202541008438_SearchStrategyNew_E_202541008438E_18-11-2025.pdf |