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Polynucleotide Constructs, Vectors, Recombinant Cells And Methods For Hydroxylating Steroids

Abstract: ABSTRACT POLYNUCLEOTIDE CONSTRUCTS, VECTORS, RECOMBINANT CELLS AND METHODS FOR HYDROXYLATING STEROIDS The present disclosure relates to polynucleotide constructs, vectors, recombinant bacterial cells and methods for hydroxylation of steroids. The recombinant bacterial cell, as disclosed, 5 expresses a heterologous bacterial CYP450 and redox partners, particularly ferredoxin reductase and ferredoxin for hydroxylating steroids, particularly at the challenging C14 position of the steroid. The present disclosure provides scalable, cost effective, and efficient production of C14 hydroxylated steroids. 10

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
31 January 2025
Publication Number
07/2025
Publication Type
INA
Invention Field
BIOTECHNOLOGY
Status
Email
Parent Application

Applicants

INDIAN INSTITUTE OF SCIENCE
Indian Institute of Science, Bangalore, Karnataka – 560012, India

Inventors

1. DAS, Debasis
INDIAN INSTITUTE OF SCIENCE, BANGALORE, Karnataka 560012, India
2. RAJENDRAN, Kalpana
INDIAN INSTITUTE OF SCIENCE, BANGALORE, Karnataka 560012, India
3. RAMACHANDRAN, Velpandi
INDIAN INSTITUTE OF SCIENCE, BANGALORE, Karnataka 560012, India

Specification

Description:AS ATTACHED , Claims:AS ATTACHED

Documents

Application Documents

# Name Date
1 202541008438-STATEMENT OF UNDERTAKING (FORM 3) [31-01-2025(online)].pdf 2025-01-31
3 202541008438-Sequence Listing in PDF [31-01-2025(online)].pdf 2025-01-31
4 202541008438-REQUEST FOR EARLY PUBLICATION(FORM-9) [31-01-2025(online)].pdf 2025-01-31
5 202541008438-POWER OF AUTHORITY [31-01-2025(online)].pdf 2025-01-31
6 202541008438-FORM-9 [31-01-2025(online)].pdf 2025-01-31
7 202541008438-FORM FOR SMALL ENTITY(FORM-28) [31-01-2025(online)].pdf 2025-01-31
8 202541008438-FORM 1 [31-01-2025(online)].pdf 2025-01-31
9 202541008438-EVIDENCE FOR REGISTRATION UNDER SSI(FORM-28) [31-01-2025(online)].pdf 2025-01-31
10 202541008438-EDUCATIONAL INSTITUTION(S) [31-01-2025(online)].pdf 2025-01-31
11 202541008438-DRAWINGS [31-01-2025(online)].pdf 2025-01-31
12 202541008438-DECLARATION OF INVENTORSHIP (FORM 5) [31-01-2025(online)].pdf 2025-01-31
13 202541008438-COMPLETE SPECIFICATION [31-01-2025(online)].pdf 2025-01-31
14 202541008438-FORM 18A [04-02-2025(online)].pdf 2025-02-04
15 202541008438-EVIDENCE OF ELIGIBILTY RULE 24C1f [04-02-2025(online)].pdf 2025-02-04
16 202541008438-FORM-8 [11-02-2025(online)].pdf 2025-02-11
17 202541008438-Proof of Right [17-02-2025(online)].pdf 2025-02-17
18 202541008438-FER.pdf 2025-11-18

Search Strategy

1 202541008438_SearchStrategyNew_E_202541008438E_18-11-2025.pdf