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A Personalized Treatment System For Colon Cancer Using Predictive Analytics

Abstract: Disclosed herein is a personalized treatment system for colon cancer using predictive analytics (100) comprises a patient data acquisition module (102) configured to collect multi-dimensional patient information. The system also includes a data preprocessing and standardization unit (104) operable to clean, normalize, and structure the acquired patient information into a digital format suitable for analysis. The system also includes a predictive analytics engine (106) configured to process the preprocessed patient information using machine learning and statistical models to generate individualized treatment recommendations. The system also includes a treatment optimization module (108) operable to dynamically update and refine treatment strategies based on ongoing patient responses and updated clinical, pathological, and molecular data. The system also includes a visualization and decision support interface (110) configured to present interpretable and transparent treatment recommendations to clinicians. The system also includes a feedback integration unit (112) operable to continuously receive post-treatment patient data and outcomes.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
07 October 2025
Publication Number
46/2025
Publication Type
INA
Invention Field
BIO-MEDICAL ENGINEERING
Status
Email
Parent Application

Applicants

SR UNIVERSITY
ANANTHSAGAR, HASANPARTHY (M), WARANGAL URBAN, TELANGANA - 506371, INDIA

Inventors

1. MAMIDALA SRUTHI
SR UNIVERSITY, ANANTHSAGAR, HASANPARTHY (M), WARANGAL URBAN, TELANGANA - 506371, INDIA
2. DR. A. RAMESH BABU
SR UNIVERSITY, ANANTHSAGAR, HASANPARTHY (M), WARANGAL URBAN, TELANGANA - 506371, INDIA

Specification

Description:FIELD OF DISCLOSURE
[0001] The present disclosure relates generally relates to the field of healthcare technologies and medical decision-support systems. More specifically, it pertains to a personalized treatment system for colon cancer using predictive analytics.
BACKGROUND OF THE DISCLOSURE
[0002] Colon cancer, also referred to as colorectal cancer when involving both the colon and rectum, represents one of the most prevalent malignancies worldwide and remains a leading cause of cancer-related morbidity and mortality. The disease originates in the epithelial lining of the colon, often beginning as benign polyps that, if left untreated, may progress into malignant tumors. With lifestyle shifts, changing dietary habits, and aging populations across the globe, the incidence of colon cancer has been steadily rising in many countries, making it not only a significant health concern but also a socioeconomic burden on healthcare systems.
[0003] The management of colon cancer has evolved substantially over the last few decades. Traditionally, surgery was considered the primary treatment modality, particularly for localized cases where tumors could be resected with curative intent. Over time, advancements in chemotherapy and radiotherapy expanded the treatment landscape, allowing for improved outcomes in patients with advanced disease. Targeted therapies and immunotherapies introduced in more recent years have opened new avenues for personalized care, yet challenges remain regarding their accessibility, cost, and applicability across heterogeneous patient populations. Despite progress, survival rates and treatment success continue to be influenced by late-stage diagnosis, variations in individual patient responses, and limitations of conventional treatment planning approaches.
[0004] One of the most pressing issues in colon cancer treatment is the heterogeneity of the disease. Colon cancer is not a uniform condition; rather, it encompasses a range of genetic mutations, molecular subtypes, and clinical presentations that contribute to varied treatment responses. For example, some patients may harbor microsatellite instability (MSI) or specific mutations, which influence the effectiveness of certain therapies. Conventional treatment regimens often fail to account for these individual differences, leading to suboptimal outcomes. Furthermore, two patients with seemingly similar clinical profiles may experience vastly different responses to the same treatment, underscoring the limitations of one-size-fits-all approaches in oncology.
[0005] The emergence of precision medicine and personalized healthcare has brought renewed focus to tailoring treatments based on genetic, molecular, and lifestyle factors. In the context of colon cancer, this shift has been particularly important given the wide variability in disease progression and treatment response. Advances in genomic sequencing and molecular profiling have made it possible to identify patient-specific biomarkers that can guide therapeutic decisions. For example, patients with MSI-high tumors may respond better to immunotherapies, while those with certain mutations may require alternative strategies. Despite these advancements, integrating such molecular insights into routine clinical decision-making remains a significant challenge, particularly in resource-constrained settings.
[0006] Predictive modeling and analytics are increasingly being explored to address the complexity of colon cancer treatment. These methods rely on large datasets comprising clinical histories, genetic profiles, imaging records, and treatment outcomes to generate predictions about disease progression and therapeutic efficacy. By identifying patterns and correlations across vast and diverse data, predictive analytics offers the potential to support clinicians in making more informed, individualized treatment decisions. However, existing approaches often struggle with issues such as data fragmentation, lack of interoperability between healthcare systems, and limited interpretability of predictive algorithms. These obstacles hinder the translation of predictive insights into actionable strategies in clinical practice.
[0007] The role of big data in cancer care has grown considerably, driven by advances in electronic health records (EHRs), genomic databases, and medical imaging technologies. For colon cancer, integrating these diverse data sources provides an opportunity to capture the full spectrum of factors influencing patient outcomes. Nevertheless, many healthcare institutions still operate in silos, where patient data is fragmented across departments or institutions, creating difficulties in achieving a holistic view of patient health. Furthermore, inconsistencies in data recording, lack of standardized formats, and privacy concerns add additional complexity. Without comprehensive and harmonized data, predictive models risk producing inaccurate or biased results, which can compromise patient care.
[0008] In addition to clinical and genetic variability, external factors such as lifestyle, comorbidities, and socioeconomic status play a crucial role in colon cancer treatment outcomes. Patients with underlying conditions such as diabetes, cardiovascular disease, or obesity may require adjustments to treatment protocols to minimize risks and side effects. Similarly, dietary habits, physical activity, and access to healthcare resources can significantly influence recovery and long-term prognosis. While such factors are widely acknowledged, they are often inadequately incorporated into treatment planning frameworks, leading to gaps in the personalization of care.
[0009] Screening and early detection efforts represent another critical component of the colon cancer landscape. Colonoscopy remains the gold standard for early detection, allowing for the removal of precancerous polyps before they progress to malignancy. Other screening methods, such as fecal occult blood tests and stool DNA tests, provide additional tools for identifying individuals at risk. Despite these advancements, challenges remain in ensuring widespread access to screening programs, particularly in low- and middle-income regions where infrastructure and resources are limited. In many cases, colon cancer continues to be diagnosed at advanced stages, where treatment options are more complex and survival rates are lower. Predictive approaches could potentially enhance screening by identifying high-risk individuals and prioritizing early interventions, but such systems are not yet widely implemented.
[0010] The economic burden of colon cancer also underscores the importance of developing more efficient treatment planning systems. Cancer treatment is inherently resource-intensive, requiring specialized personnel, facilities, and technologies. In high-income countries, advances in therapies such as monoclonal antibodies and checkpoint inhibitors have improved outcomes, but their high costs often limit accessibility. In contrast, low- and middle-income countries struggle with access to even basic diagnostic and therapeutic resources, leading to disparities in outcomes across populations. Predictive systems capable of optimizing resource allocation and guiding cost-effective treatment strategies are therefore seen as crucial in addressing both clinical and economic challenges.
[0011] Ethical considerations further complicate the personalization of colon cancer treatment. The use of predictive analytics and artificial intelligence in healthcare introduces concerns regarding patient consent, data privacy, and algorithmic bias. For instance, predictive models trained on datasets from specific populations may not generalize well to other groups, potentially leading to inequities in care. Ensuring transparency, fairness, and accountability in predictive systems is critical for their acceptance among healthcare providers and patients. Moreover, clinicians may be hesitant to rely on algorithmic recommendations if the decision-making processes are not explainable or aligned with established medical practices.
[0012] Current research efforts continue to explore how predictive analytics, machine learning, and artificial intelligence can be integrated into oncology practice to provide meaningful improvements in patient care. Studies have demonstrated the feasibility of using predictive models to forecast treatment responses, survival rates, and recurrence risks in colon cancer patients. However, these models often remain confined to academic or experimental settings, with limited adoption in clinical environments. Bridging the gap between research and practice requires robust validation, integration with existing clinical workflows, and support from healthcare policymakers and institutions.
[0013] Globally, initiatives to create cancer registries, genomic databases, and collaborative research networks are contributing to the growth of predictive oncology. For colon cancer, such initiatives aim to generate insights that can be generalized across diverse patient populations, thereby improving the robustness and applicability of predictive systems. At the same time, advances in wearable technologies, remote monitoring, and patient-reported outcomes are expanding the scope of data available for analysis. These innovations hold promise for creating more dynamic and responsive treatment systems that adapt to patient needs over time, rather than relying solely on static treatment plans determined at the outset of care.
[0014] Despite the progress achieved in colon cancer management, there remains a pressing need for systems that can unify data, account for patient-specific variability, and provide actionable insights for personalized treatment. Conventional approaches, while effective for some patients, fall short in addressing the multifaceted nature of the disease and the complexity of treatment decisions. Predictive analytics, with its ability to harness large datasets and uncover hidden patterns, offers a powerful tool to bridge these gaps. Nevertheless, significant challenges in data integration, model validation, ethical governance, and clinical implementation must be addressed before predictive systems can be fully realized in routine colon cancer care.
[0015] Thus, in light of the above-stated discussion, there exists a need for a personalized treatment system for colon cancer using predictive analytics.

SUMMARY OF THE DISCLOSURE
[0016] The following is a summary description of illustrative embodiments of the invention. It is provided as a preface to assist those skilled in the art to more rapidly assimilate the detailed design discussion which ensues and is not intended in any way to limit the scope of the claims which are appended hereto in order to particularly point out the invention.
[0017] According to illustrative embodiments, the present disclosure focuses on a personalized treatment system for colon cancer using predictive analytics which overcomes the above-mentioned disadvantages or provide the users with a useful or commercial choice.
[0018] An objective of the present disclosure is to validate predictive models through retrospective and prospective clinical trials, ensuring robustness, accuracy, and real-world applicability of the personalized treatment system.
[0019] Another objective of the present disclosure is to develop a predictive analytics framework capable of integrating heterogeneous patient data, including clinical history, tumor biology, genetic sequencing, and molecular profiles, for colon cancer treatment personalization.
[0020] Another objective of the present disclosure is to design algorithms for individualized treatment prediction that recommend optimal therapeutic strategies such as chemotherapy regimens, targeted therapy, immunotherapy, or surgical interventions based on patient-specific characteristics.
[0021] Another objective of the present disclosure is to establish dynamic risk stratification models that assess recurrence probability, treatment resistance, and adverse side effect likelihood in colon cancer patients.
[0022] Another objective of the present disclosure is to incorporate real-time data monitoring and feedback loops enabling continuous adjustment of treatment protocols in response to changes in patient health status, tumor progression, or therapy response.
[0023] Another objective of the present disclosure is to minimize adverse effects and improve quality of life by predicting toxicity levels and tailoring drug dosage and combination therapies to patient-specific tolerances.
[0024] Another objective of the present disclosure is to integrate multi-omics data analysis (genomics, proteomics, transcriptomics, and metabolomics) with clinical and imaging data for holistic patient profiling in colon cancer management.
[0025] Another objective of the present disclosure is to provide clinical decision support tools that assist oncologists in selecting evidence-based, personalized treatment plans aligned with predictive models.
[0026] Another objective of the present disclosure is to create a secure data-sharing ecosystem that enables collaboration among oncologists, researchers, and healthcare institutions while ensuring patient data privacy and compliance with medical regulations.
[0027] Yet another objective of the present disclosure is to contribute to precision oncology by reducing recurrence rates, improving survival outcomes, and enhancing the overall efficiency of colon cancer treatment through advanced data-driven personalization.
[0028] In light of the above, a personalized treatment system for colon cancer using predictive analytics comprises a patient data acquisition module configured to collect multi-dimensional patient information. The system also includes a data preprocessing and standardization unit operable to clean, normalize, and structure the acquired patient information into a digital format suitable for analysis. The system also includes a predictive analytics engine configured to process the preprocessed patient information using machine learning and statistical models to generate individualized treatment recommendations. The system also includes a treatment optimization module operable to dynamically update and refine treatment strategies based on ongoing patient responses and updated clinical, pathological, and molecular data. The system also includes a visualization and decision support interface configured to present interpretable and transparent treatment recommendations to clinicians. The system also includes a feedback integration unit operable to continuously receive post-treatment patient data and outcomes.
[0029] In one embodiment, the patient data acquisition module is configured to collect patient demographic information, medical history, genetic markers, imaging data, laboratory test results, and lifestyle parameters.
[0030] In one embodiment, the data preprocessing and standardization unit is further configured to remove erroneous, incomplete, or duplicate patient information and to encode categorical variables into machine-readable formats.
[0031] In one embodiment, the predictive analytics engine employs supervised, unsupervised, and reinforcement learning algorithms to analyze patient-specific tumor characteristics, genetic mutations, and prior treatment responses.
[0032] In one embodiment, the treatment optimization module is further operable to simulate multiple treatment scenarios and select an optimal treatment plan based on predicted efficacy, toxicity, and patient-specific risk factors.
[0033] In one embodiment, the visualization and decision support interface provides interactive dashboards, charts, and probability scores for recommended treatments, allowing clinicians to evaluate alternative treatment strategies.
[0034] In one embodiment, the feedback integration unit is further configured to incorporate real-time patient monitoring data, laboratory results, and follow-up imaging studies to iteratively refine the predictive analytics engine.
[0035] In one embodiment, the predictive analytics engine is further configured to identify potential clinical trial eligibility for the patient based on molecular profiling and historical outcomes.
[0036] In one embodiment, the treatment optimization module includes a rule-based engine that incorporates current clinical guidelines, expert physician recommendations, and evidence-based protocols in refining treatment strategies.
[0037] In one embodiment, the patient data acquisition module is further operable to integrate data from wearable devices, electronic health records, and patient-reported outcomes to enrich the predictive analytics engine.
[0038] These and other advantages will be apparent from the present application of the embodiments described herein.
[0039] The preceding is a simplified summary to provide an understanding of some embodiments of the present invention. This summary is neither an extensive nor exhaustive overview of the present invention and its various embodiments. The summary presents selected concepts of the embodiments of the present invention in a simplified form as an introduction to the more detailed description presented below. As will be appreciated, other embodiments of the present invention are possible utilizing, alone or in combination, one or more of the features set forth above or described in detail below.
[0040] These elements, together with the other aspects of the present disclosure and various features are pointed out with particularity in the claims annexed hereto and form a part of the present disclosure. For a better understanding of the present disclosure, its operating advantages, and the specified object attained by its uses, reference should be made to the accompanying drawings and descriptive matter in which there are illustrated exemplary embodiments of the present disclosure.
BRIEF DESCRIPTION OF THE DRAWINGS
[0041] To describe the technical solutions in the embodiments of the present disclosure or in the prior art more clearly, the following briefly describes the accompanying drawings required for describing the embodiments or the prior art. Apparently, the accompanying drawings in the following description merely show some embodiments of the present disclosure, and a person of ordinary skill in the art can derive other implementations from these accompanying drawings without creative efforts. All of the embodiments or the implementations shall fall within the protection scope of the present disclosure.
[0042] The advantages and features of the present disclosure will become better understood with reference to the following detailed description taken in conjunction with the accompanying drawing, in which:
[0043] FIG. 1 illustrates a flowchart outlining sequential step involved in a personalized treatment system for colon cancer using predictive analytics, in accordance with an exemplary embodiment of the present disclosure;
[0044] FIG. 2 illustrates a flowchart showing working of a personalized treatment system for colon cancer using predictive analytics, in accordance with an exemplary embodiment of the present disclosure.
[0045] Like reference, numerals refer to like parts throughout the description of several views of the drawing;
[0046] The personalized treatment system for colon cancer using predictive analytics, which like reference letters indicate corresponding parts in the various figures. It should be noted that the accompanying figure is intended to present illustrations of exemplary embodiments of the present disclosure. This figure is not intended to limit the scope of the present disclosure. It should also be noted that the accompanying figure is not necessarily drawn to scale.
DETAILED DESCRIPTION OF THE DISCLOSURE
[0047] The following is a detailed description of embodiments of the disclosure depicted in the accompanying drawings. The embodiments are in such detail as to communicate the disclosure. However, the amount of detail offered is not intended to limit the anticipated variations of embodiments; on the contrary, the intention is to cover all modifications, equivalents, and alternatives falling within the spirit and scope of the present disclosure.
[0048] In the following description, numerous specific details are set forth in order to provide a thorough understanding of the embodiments of the present disclosure. It may be apparent to one skilled in the art that embodiments of the present disclosure may be practiced without some of these specific details.
[0049] Various terms as used herein are shown below. To the extent a term is used, it should be given the broadest definition persons in the pertinent art have given that term as reflected in printed publications and issued patents at the time of filing.
[0050] The terms “a” and “an” herein do not denote a limitation of quantity, but rather denote the presence of at least one of the referenced items.
[0051] The terms “having”, “comprising”, “including”, and variations thereof signify the presence of a component.
[0052] Referring now to FIG. 1 to FIG. 2 to describe various exemplary embodiments of the present disclosure. FIG. 1 illustrates a flowchart outlining sequential step involved in a personalized treatment system for colon cancer using predictive analytics, in accordance with an exemplary embodiment of the present disclosure.
[0053] A personalized treatment system for colon cancer using predictive analytics 100 comprises a patient data acquisition module 102 configured to collect multi-dimensional patient information. The patient data acquisition module 102 is configured to collect patient demographic information, medical history, genetic markers, imaging data, laboratory test results, and lifestyle parameters. The patient data acquisition module 102 is further operable to integrate data from wearable devices, electronic health records, and patient-reported outcomes to enrich the predictive analytics engine.
[0054] The system also includes a data preprocessing and standardization unit 104 operable to clean, normalize, and structure the acquired patient information into a digital format suitable for analysis. The data preprocessing and standardization unit 104 is further configured to remove erroneous, incomplete, or duplicate patient information and to encode categorical variables into machine-readable formats.
[0055] The system also includes a predictive analytics engine 106 configured to process the preprocessed patient information using machine learning and statistical models to generate individualized treatment recommendations. The predictive analytics engine 106 employs supervised, unsupervised, and reinforcement learning algorithms to analyze patient-specific tumor characteristics, genetic mutations, and prior treatment responses. The predictive analytics engine 106 is further configured to identify potential clinical trial eligibility for the patient based on molecular profiling and historical outcomes.
[0056] The system also includes a treatment optimization module 108 operable to dynamically update and refine treatment strategies based on ongoing patient responses and updated clinical, pathological, and molecular data. The treatment optimization module 108 is further operable to simulate multiple treatment scenarios and select an optimal treatment plan based on predicted efficacy, toxicity, and patient-specific risk factors. The treatment optimization module 108 includes a rule-based engine that incorporates current clinical guidelines, expert physician recommendations, and evidence-based protocols in refining treatment strategies.
[0057] The system also includes a visualization and decision support interface 110 configured to present interpretable and transparent treatment recommendations to clinicians. The visualization and decision support interface 110 provides interactive dashboards, charts, and probability scores for recommended treatments, allowing clinicians to evaluate alternative treatment strategies.
[0058] The system also includes a feedback integration unit 112 operable to continuously receive post-treatment patient data and outcomes. The feedback integration unit 112 is further configured to incorporate real-time patient monitoring data, laboratory results, and follow-up imaging studies to iteratively refine the predictive analytics engine.
[0059] FIG. 1 illustrates a flowchart outlining sequential step involved in a personalized treatment system for colon cancer using predictive analytics.
[0060] At 102, the patient data acquisition module serves as the foundation of the system, gathering comprehensive multi-dimensional patient information. This includes clinical records, genetic profiles, pathological reports, imaging data, lifestyle factors, and any relevant comorbidities. By consolidating such heterogeneous data, the module ensures that the system has a holistic view of the patient’s health status, which is essential for generating meaningful insights.
[0061] At 104, once the patient information is collected, it is directed to the data preprocessing and standardization unit. This unit plays a critical role in ensuring the integrity and usability of the data by performing cleaning, normalization, and structuring processes. Noisy, incomplete, or inconsistent entries are detected and corrected or imputed, while diverse data formats are converted into a uniform digital representation compatible with advanced computational analysis. This step ensures that subsequent predictive models receive high-quality, standardized data, minimizing biases and errors in treatment recommendations.
[0062] At 106, the preprocessed and structured patient data is then fed into the predictive analytics engine, which constitutes the core analytical component of the system. Utilizing a combination of machine learning algorithms and statistical modeling techniques, the engine analyzes patient-specific information to identify patterns, correlations, and predictive biomarkers relevant to colon cancer progression and treatment response. By leveraging historical clinical data and evidence-based guidelines, the engine generates individualized treatment recommendations that account for the unique biological and clinical profile of each patient. These recommendations may include optimal chemotherapy regimens, targeted therapies, immunotherapy options, and other relevant interventions.
[0063] At 108, following the generation of preliminary recommendations, the treatment optimization module comes into play, enabling the dynamic refinement of treatment strategies. This module continuously evaluates patient responses to administered therapies and integrates new clinical, pathological, and molecular data as they become available. By iteratively updating treatment plans, the module ensures that therapeutic interventions remain adaptive, personalized, and optimized for maximal efficacy while minimizing adverse effects. This dynamic adaptability is particularly valuable in oncology, where tumor characteristics and patient conditions can evolve rapidly over time.
[0064] At 110, to facilitate clinical adoption and informed decision-making, the visualization and decision support interface presents the insights and treatment recommendations in an interpretable, transparent, and user-friendly format. This interface translates complex predictive analytics outputs into visualizations, risk scores, and comparative treatment scenarios that enable clinicians to understand the rationale behind each recommendation. By providing a clear representation of potential outcomes and treatment pathways, the interface supports shared decision-making between healthcare providers and patients.
[0065] At 112, the feedback integration unit ensures a continuous learning cycle within the system. It receives post-treatment patient data, including observed outcomes, side effects, and longitudinal health information, and channels this data back into the predictive analytics engine. This feedback loop allows the system to refine its models over time, enhancing predictive accuracy and the quality of future treatment recommendations. Collectively, the flowchart depicts a comprehensive, end-to-end workflow in which patient data acquisition, preprocessing, predictive analytics, treatment optimization, visualization, and feedback integration are seamlessly interconnected, enabling a highly personalized, adaptive, and evidence-based approach to colon cancer management.
[0066] FIG. 2 illustrates a flowchart showing working of a personalized treatment system for colon cancer using predictive analytics.
[0067] The workflow is divided into two major sections: diagnosis and disease progression monitoring, each contributing to individualized therapy planning.
[0068] On the left side, the diagnosis pathway begins with an initial diagnostic assessment to determine the molecular characteristics of the tumor, specifically whether the patient exhibits high microsatellite instability (MSI-H) or deficiency in mismatch repair (dMMR). This step is crucial as it directly influences the subsequent therapeutic approach. If the tumor is identified as MSI-H or dMMR positive, the workflow directs the patient toward immunotherapy, leveraging the patient’s immune system to target and eliminate cancer cells, a treatment known to be highly effective for this subtype due to the tumor’s heightened mutational burden and immune visibility.
[0069] If the tumor does not exhibit MSI-H or dMMR characteristics, the workflow evaluates the RAS/RAF mutation status. This genetic determination is pivotal in guiding targeted therapy. For patients with wild-type RAS/RAF genes, the recommended treatment involves a combination of anti-EGFR therapy and chemotherapy. Anti-EGFR therapy works by inhibiting the epidermal growth factor receptor pathway, which is often overactive in wild-type tumors, while chemotherapy targets rapidly dividing cells more generally. Conversely, for patients with mutant RAS/RAF genes, the system directs the therapeutic approach toward VEGF inhibitor therapy combined with chemotherapy. VEGF inhibitors function by blocking angiogenesis, thereby restricting the tumor’s blood supply and growth potential.
[0070] On the right side of the workflow, the progression pathway addresses ongoing monitoring of disease evolution. This includes performing liquid biopsy analysis, a minimally invasive method that detects tumor-derived genetic material circulating in the blood. This step is followed by resistance mutation analysis, which identifies genetic alterations that may confer resistance to current therapies. By integrating these dynamic molecular insights, clinicians can adjust treatment regimens in real-time, ensuring that therapy remains effective as the tumor evolves.
[0071] While the invention has been described in connection with what is presently considered to be the most practical and various embodiments, it will be understood that the invention is not to be limited to the disclosed embodiments, but on the contrary, is intended to cover various modifications and equivalent arrangements included within the scope of the appended claims.
[0072] A person of ordinary skill in the art may be aware that, in combination with the examples described in the embodiments disclosed in this specification, units and algorithm steps may be implemented by electronic hardware, computer software, or a combination thereof.
[0073] The foregoing descriptions of specific embodiments of the present disclosure have been presented for purposes of illustration and description. They are not intended to be exhaustive or to limit the present disclosure to the precise forms disclosed, and many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described to best explain the principles of the present disclosure and its practical application, and to thereby enable others skilled in the art to best utilize the present disclosure and various embodiments with various modifications as are suited to the particular use contemplated. It is understood that various omissions and substitutions of equivalents are contemplated as circumstances may suggest or render expedient, but such omissions and substitutions are intended to cover the application or implementation without departing from the scope of the present disclosure.
[0074] Disjunctive language such as the phrase “at least one of X, Y, Z,” unless specifically stated otherwise, is otherwise understood with the context as used in general to present that an item, term, etc., may be either X, Y, or Z, or any combination thereof (e.g., X, Y, and/or Z). Thus, such disjunctive language is not generally intended to, and should not, imply that certain embodiments require at least one of X, at least one of Y, or at least one of Z to each be present.
[0075] In a case that no conflict occurs, the embodiments in the present disclosure and the features in the embodiments may be mutually combined. The foregoing descriptions are merely specific implementations of the present disclosure, but are not intended to limit the protection scope of the present disclosure. Any variation or replacement readily figured out by a person skilled in the art within the technical scope disclosed in the present disclosure shall fall within the protection scope of the present disclosure. Therefore, the protection scope of the present disclosure shall be subject to the protection scope of the claims.
, Claims:I/We Claim:
1. A personalized treatment system for colon cancer using predictive analytics (100) comprising:
a patient data acquisition module (102) configured to collect multi-dimensional patient information;
a data preprocessing and standardization unit (104) operable to clean, normalize, and structure the acquired patient information into a digital format suitable for analysis;
a predictive analytics engine (106) configured to process the preprocessed patient information using machine learning and statistical models to generate individualized treatment recommendations;
a treatment optimization module (108) operable to dynamically update and refine treatment strategies based on ongoing patient responses and updated clinical, pathological, and molecular data;
a visualization and decision support interface (110) configured to present interpretable and transparent treatment recommendations to clinicians;
a feedback integration unit (112) operable to continuously receive post-treatment patient data and outcomes.
2. The system (100) as claimed in claim 1, wherein the patient data acquisition module (102) is configured to collect patient demographic information, medical history, genetic markers, imaging data, laboratory test results, and lifestyle parameters.
3. The system (100) as claimed in claim 1, wherein the data preprocessing and standardization unit (104) is further configured to remove erroneous, incomplete, or duplicate patient information and to encode categorical variables into machine-readable formats.
4. The system (100) as claimed in claim 1, wherein the predictive analytics engine (106) employs supervised, unsupervised, and reinforcement learning algorithms to analyze patient-specific tumor characteristics, genetic mutations, and prior treatment responses.
5. The system (100) as claimed in claim 1, wherein the treatment optimization module (108) is further operable to simulate multiple treatment scenarios and select an optimal treatment plan based on predicted efficacy, toxicity, and patient-specific risk factors.
6. The system (100) as claimed in claim 1, wherein the visualization and decision support interface (110) provides interactive dashboards, charts, and probability scores for recommended treatments, allowing clinicians to evaluate alternative treatment strategies.
7. The system (100) as claimed in claim 1, wherein the feedback integration unit (112) is further configured to incorporate real-time patient monitoring data, laboratory results, and follow-up imaging studies to iteratively refine the predictive analytics engine.
8. The system (100) as claimed in claim 1, wherein the predictive analytics engine (106) is further configured to identify potential clinical trial eligibility for the patient based on molecular profiling and historical outcomes.
9. The system (100) as claimed in claim 1, wherein the treatment optimization module (108) includes a rule-based engine that incorporates current clinical guidelines, expert physician recommendations, and evidence-based protocols in refining treatment strategies.
10. The system (100) as claimed in claim 1, wherein the patient data acquisition module (102) is further operable to integrate data from wearable devices, electronic health records, and patient-reported outcomes to enrich the predictive analytics engine.

Documents

Application Documents

# Name Date
1 202541096540-STATEMENT OF UNDERTAKING (FORM 3) [07-10-2025(online)].pdf 2025-10-07
2 202541096540-REQUEST FOR EARLY PUBLICATION(FORM-9) [07-10-2025(online)].pdf 2025-10-07
3 202541096540-POWER OF AUTHORITY [07-10-2025(online)].pdf 2025-10-07
4 202541096540-FORM-9 [07-10-2025(online)].pdf 2025-10-07
5 202541096540-FORM FOR SMALL ENTITY(FORM-28) [07-10-2025(online)].pdf 2025-10-07
6 202541096540-FORM 1 [07-10-2025(online)].pdf 2025-10-07
7 202541096540-EVIDENCE FOR REGISTRATION UNDER SSI(FORM-28) [07-10-2025(online)].pdf 2025-10-07
8 202541096540-DRAWINGS [07-10-2025(online)].pdf 2025-10-07
9 202541096540-DECLARATION OF INVENTORSHIP (FORM 5) [07-10-2025(online)].pdf 2025-10-07
10 202541096540-COMPLETE SPECIFICATION [07-10-2025(online)].pdf 2025-10-07
11 202541096540-Proof of Right [16-10-2025(online)].pdf 2025-10-16