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Combination Of Anticancer Agents Comprising A Bifunctional Compound With G12 D Mutant Kras Inhibitory Activity

Abstract: There is provided herein a combination of compound of formula (I) which is a bifunctional compound with G12D mutant KRAS inhibitory activity or a pharmaceutically acceptable salt thereof and an anti cancer agent for use in the treatment of cancer wherein the compound of formula (I) and the anti cancer agent are as described in the description.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
06 March 2025
Publication Number
12/2025
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
Parent Application

Applicants

ASTELLAS PHARMA INC.
2 5 1 Nihonbashi Honcho Chuo ku Tokyo 103 8411

Inventors

1. NAGASHIMA Takeyuki
2 5 1 Nihonbashi Honcho Chuo ku Tokyo 103 8411
2. TASAKI Mamoru
2 5 1 Nihonbashi Honcho Chuo ku Tokyo 103 8411

Specification

Documents

Application Documents

# Name Date
1 202547020119-STATEMENT OF UNDERTAKING (FORM 3) [06-03-2025(online)].pdf 2025-03-06
2 202547020119-REQUEST FOR EXAMINATION (FORM-18) [06-03-2025(online)].pdf 2025-03-06
3 202547020119-PROOF OF RIGHT [06-03-2025(online)].pdf 2025-03-06
4 202547020119-PRIORITY DOCUMENTS [06-03-2025(online)].pdf 2025-03-06
5 202547020119-NOTIFICATION OF INT. APPLN. NO. & FILING DATE (PCT-RO-105-PCT Pamphlet) [06-03-2025(online)].pdf 2025-03-06
6 202547020119-FORM 18 [06-03-2025(online)].pdf 2025-03-06
7 202547020119-FORM 1 [06-03-2025(online)].pdf 2025-03-06
8 202547020119-DECLARATION OF INVENTORSHIP (FORM 5) [06-03-2025(online)].pdf 2025-03-06
9 202547020119-COMPLETE SPECIFICATION [06-03-2025(online)].pdf 2025-03-06
10 202547020119-CLAIMS UNDER RULE 1 (PROVISIO) OF RULE 20 [06-03-2025(online)].pdf 2025-03-06
11 202547020119-FORM-26 [07-03-2025(online)].pdf 2025-03-07
12 202547020119-RELEVANT DOCUMENTS [12-03-2025(online)].pdf 2025-03-12
13 202547020119-MARKED COPIES OF AMENDEMENTS [12-03-2025(online)].pdf 2025-03-12
14 202547020119-FORM 13 [12-03-2025(online)].pdf 2025-03-12
15 202547020119-Annexure [12-03-2025(online)].pdf 2025-03-12
16 202547020119-AMMENDED DOCUMENTS [12-03-2025(online)].pdf 2025-03-12
17 202547020119-FORM 3 [21-08-2025(online)].pdf 2025-08-21