Abstract: Embodiments of the present disclosure generally relate to combination therapies and methods for myelin growth and/or remyelination. Embodiments described herein also relate to such combination therapies and methods used for the treatment of various diseases or medical conditions, such as age-related hearing loss, in a patient. In an embodiment, a combination therapy for stimulating remyelination of a neuron in a patient having hearing loss is provided. The combination therapy includes a pharmaceutical or pharmaceutical composition, the pharmaceutical or pharmaceutical composition comprising an antihistamine, a remyelination therapy, a therapy prescribed for treatment of multiple sclerosis, or combinations thereof. The combination therapy further includes an audio file configured to facilitate remyelination of a neuron upon administration of the pharmaceutical or pharmaceutical composition.