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3 Alkylidenehydrazino Substituted Heteroaryl Compounds As Thrombopoietin Receptor Activators
A compound represented by the formula. (1) : 5 wherein a is a nitrogen atom or cr4. B is an oxygen atom, a sulfur atom or NS9 (provided that when A is a nitrogenatom, B is not NH) , R1 is a C2_14 aryl group, L1 is a bond,CR10R11, an oxygen atom, a sulfur atom or NR12, X is OR13,SR23 or NR14NR15, R2 is a hydrogen atom, a formyl group, aC1-10 alkyl group or the like, L2 is a bond or the like, L3is a bond, CR17R18, an oxygen atom, a sulfur atom or NR19,L4 is a bond, CR20R21, an oxygen atom, a sulfur atom or NR22, Y is an oxygen atom, a sulfur atom or NR23, and R3is a C2-14 aryl group, a tautomer, prodrug orpharmaceutically acceptable salt of compound or asolvate thereof.
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
05 October 2005
Publication Number
39/2006
Publication Type
Invention Field
PHARMACEUTICALS
Status
Email
Parent Application
Patent Number
Legal Status
Grant Date
2017-04-20
Renewal Date
Applicants
NISSAN CHEMICAL INDUSTRIES, LTD.
7-1, KANDA-NISHIKI-CHO 3-CHOME, CHIYODA-KU, TOKYO 1010054, JAPAN.
Inventors
1. OWADA SHINGO
C/O NISSAN CHEMICAL INDUSTRIES, LTD.,
CHEMICAL RESEARCH LABORATORIES,
722-1, TSUBOI-CHO, FUNABASHI-SHI, CHIBA 2748507, JAPAN.
2. IWAMOTO SHUNSUKE
C/O NISSAN CHEMICAL INDUSTRIES, LTD.,
CHEMICAL RESEARCH LABORATORIES,
722-1, TSUBOI-CHO, FUNABASHI-SHI, CHIBA 2748507, JAPAN.
3. YANAGIHARA KAZUFUMI
C/O NISSAN CHEMICAL INDUSTRIES, LTD.,
CHEMICAL RESEARCH LABORATORIES,
722-1, TSUBOI-CHO, FUNABASHI-SHI, CHIBA 2748507, JAPAN.
4. MIYAJI KATSUAKI
C/O NISSAN CHEMICAL INDUSTRIES, LTD.,
CHEMICAL RESEARCH LABORATORIES,
722-1, TSUBOI-CHO, FUNABASHI-SHI, CHIBA 2748507, JAPAN.
5. NAKAMURA TAKANORI
C/O NISSAN CHEMICAL INDUSTRIES, LTD.,
BIOLOGICAL RESEARCH LABORATORIES, 1470,
OAZA-SHIRAOKA, SHIRAOKA-MACHI, MINAMISAITAMA-GUN,
SAITAMA 3490218. JAPAN.
6. ISHIWATA NORIHISA
C/O NISSAN CHEMICAL INDUSTRIES, LTD.,
BIOLOGICAL RESEARCH LABORATORIES, 1470,
OAZA-SHIRAOKA, SHIRAOKA-MACHI, MINAMISAITAMA-GUN,
SAITAMA 3490218. JAPAN.
7. HIROKAWA YUTAKA
C/O NISSAN CHEMICAL INDUSTRIES, LTD.,
CHEMICAL RESEARCH LABORATORIES,
722-1, TSUBOI-CHO, FUNABASHI-SHI, CHIBA 2748507, JAPAN.
Specification
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 1967-KOLNP-2005-(05-10-2005)-CORRESPONDENCE.pdf | 2005-10-05 |
| 2 | 1967-KOLNP-2005-(03-11-2005)-CORRESPONDENCE.pdf | 2005-11-03 |
| 3 | 1967-KOLNP-2005-(04-01-2006)-CORRESPONDENCE.pdf | 2006-01-04 |
| 4 | 1967-KOLNP-2005-(04-06-2007)-CORRESPONDENCE.pdf | 2007-06-04 |
| 5 | abstract-01967-kolnp-2005.jpg | 2011-10-07 |
| 6 | 01967-kolnp-2005-international publication.pdf | 2011-10-07 |
| 7 | 01967-kolnp-2005-form 5.pdf | 2011-10-07 |
| 8 | 01967-kolnp-2005-form 3.pdf | 2011-10-07 |
| 9 | 01967-kolnp-2005-form 1.pdf | 2011-10-07 |
| 10 | 01967-kolnp-2005-description complete.pdf | 2011-10-07 |
| 11 | 01967-kolnp-2005-claims.pdf | 2011-10-07 |
| 12 | 01967-kolnp-2005-abstract.pdf | 2011-10-07 |
| 13 | 1967-KOLNP-2005-(21-01-2014)-CORRESPONDENCE.pdf | 2014-01-21 |
| 14 | 1967-KOLNP-2005-(11-08-2014)-REPLY TO EXAMINATION REPORT.pdf | 2014-08-11 |
| 15 | 1967-KOLNP-2005-(11-08-2014)-CORRESPONDENCE.pdf | 2014-08-11 |
| 16 | 1967-KOLNP-2005-FORM-13.pdf | 2014-10-27 |
| 17 | 1967-KOLNP-2005-(26-10-2015)-REPLY TO EXAMINATION REPORT.pdf | 2015-10-26 |
| 18 | 1967-KOLNP-2005-(26-10-2015)-PETITION UNDER RULE 137.pdf | 2015-10-26 |
| 19 | 1967-KOLNP-2005-(26-10-2015)-PA.pdf | 2015-10-26 |
| 20 | 1967-KOLNP-2005-(26-10-2015)-OTHERS.pdf | 2015-10-26 |
| 21 | 1967-KOLNP-2005-(26-10-2015)-FORM-2.pdf | 2015-10-26 |
| 22 | 1967-KOLNP-2005-(26-10-2015)-CORRESPONDENCE.pdf | 2015-10-26 |
| 23 | 1967-KOLNP-2005-(26-10-2015)-CLAIMS.pdf | 2015-10-26 |
| 24 | 1967-KOLNP-2005-(26-10-2015)-ANNEXURE TO FORM 3.pdf | 2015-10-26 |
| 25 | 1967-KOLNP-2005-(26-10-2015)-ABSTRACT.pdf | 2015-10-26 |
| 26 | HEARING ADJOURNMENT [24-02-2017(online)].pdf | 2017-02-24 |
| 27 | Petition Under Rule 137 [10-04-2017(online)].pdf_242.pdf | 2017-04-10 |
| 28 | Petition Under Rule 137 [10-04-2017(online)].pdf | 2017-04-10 |
| 29 | Other Patent Document [10-04-2017(online)].pdf_296.pdf | 2017-04-10 |
| 30 | Other Patent Document [10-04-2017(online)].pdf | 2017-04-10 |
| 31 | 1967-KOLNP-2005-PETITION UNDER RULE 137.pdf | 2017-05-15 |
| 32 | 1967-KOLNP-2005-MARK OF COPY.pdf | 2017-05-15 |
| 33 | 1967-KOLNP-2005-HEARING NOTICE.pdf | 2017-05-15 |
| 34 | 1967-KOLNP-2005-GRANTED-SPECIFICATION-COMPLETE.pdf | 2017-05-15 |
| 35 | 1967-KOLNP-2005-GRANTED-SPECIFICATION-COMPLETE-3.pdf | 2017-05-15 |
| 36 | 1967-KOLNP-2005-GRANTED-SPECIFICATION-COMPLETE-2.pdf | 2017-05-15 |
| 37 | 1967-KOLNP-2005-GRANTED-SPECIFICATION-COMPLETE-1.pdf | 2017-05-15 |
| 38 | 1967-KOLNP-2005-GRANTED-LETTER PATENT.pdf | 2017-05-15 |
| 39 | 1967-KOLNP-2005-GRANTED-FORM 5.pdf | 2017-05-15 |
| 40 | 1967-KOLNP-2005-GRANTED-FORM 3.pdf | 2017-05-15 |
| 41 | 1967-KOLNP-2005-GRANTED-FORM 2.pdf | 2017-05-15 |
| 42 | 1967-KOLNP-2005-GRANTED-FORM 1.pdf | 2017-05-15 |
| 43 | 1967-KOLNP-2005-GRANTED-DRAWINGS.pdf | 2017-05-15 |
| 44 | 1967-KOLNP-2005-GRANTED-DESCRIPTION (COMPLETE).pdf | 2017-05-15 |
| 45 | 1967-KOLNP-2005-GRANTED-DESCRIPTION (COMPLETE)-3.pdf | 2017-05-15 |
| 46 | 1967-KOLNP-2005-GRANTED-DESCRIPTION (COMPLETE)-2.pdf | 2017-05-15 |
| 47 | 1967-KOLNP-2005-GRANTED-DESCRIPTION (COMPLETE)-1.pdf | 2017-05-15 |
| 48 | 1967-KOLNP-2005-GRANTED-CLAIMS.pdf | 2017-05-15 |
| 49 | 1967-KOLNP-2005-GRANTED-ABSTRACT.pdf | 2017-05-15 |
| 50 | 1967-KOLNP-2005-GPA.pdf | 2017-05-15 |
| 51 | 1967-kolnp-2005-FORM 18.pdf | 2017-05-15 |
| 52 | 1967-KOLNP-2005-FORM 13.pdf | 2017-05-15 |
| 53 | 1967-KOLNP-2005-FIRST EXAMINATION REPORT.pdf | 2017-05-15 |
| 54 | 1967-KOLNP-2005-DECISION UNDER SECTION 15.pdf | 2017-05-15 |
| 55 | 1967-KOLNP-2005-CANCELLED PAGES.pdf | 2017-05-15 |
| 56 | 1967-KOLNP-2005-ASSIGNMENT.pdf | 2017-05-15 |
| 57 | 1967-KOLNP-2005-RELEVANT DOCUMENTS [19-02-2018(online)].pdf | 2018-02-19 |
| 58 | 1967-KOLNP-2005-RELEVANT DOCUMENTS [21-02-2019(online)].pdf | 2019-02-21 |
| 59 | 1967-KOLNP-2005-RELEVANT DOCUMENTS [24-02-2020(online)].pdf | 2020-02-24 |