3 Substituted Pyridazine Compounds As Smarca2 And/Or Smarca4 Degraders

Abstract: The present invention provides 3 substituted pyridazine compound of formula (I) which are therapeutically useful as SMARCA2 and/or SMARCA4 degraders. These compounds are useful in the treatment and/or prevention of diseases or disorders dependent upon SMARCA2 and/or SMARCA4 in a subject. The present invention also provides preparation of the compounds and pharmaceutical compositions comprising a compound of formula (I) or a pharmaceutically acceptable salt or a stereoisomer or a tautomer thereof.

Patent Information

Application #

Filing Date

02 September 2024

Publication Number

52/2024

Publication Type

INA

Invention Field

CHEMICAL

Status

Email

Parent Application

Applicants

AURIGENE ONCOLOGY LIMITED

39 40 KIADB Industrial Area Electronic City Phase II Hosur Road Bangalore 560100

Inventors

1. ABBINENI Chandrasekhar

H. No: 15 21 48/14/G 3 Sri Sai Datta Enclave Balaji Nagar Kukatpally Telangana. Hyderabad 500 072

2. SAMAJDAR Susanta

Flat # R801 H. M Tambourine Jaraganahalli J.P. Nagar 6th Phase Bangalore 560 078

3. SASMAL Sanjita

2B 706 SMR vinay city Bollaram Road Miyapur Telangana Hyderabad 560 049

4. KUILA Bilash

Vill+PO+PS Shyampur Dist Howrah West Bengal Howrah 711314

5. MUKHERJEE Subhendu

132/A/3 Thakurbari Street (Kokil Bagan) P.O. Serampore Hooghly 712201

6. TATYASAHEB GORE Suraj

Nandur Bk Taluka: Rahata Dist: Ahmednagar Maharashtra 413720

Specification

Documents

Application Documents

#	Name	Date
1	202447066226-PRIORITY DOCUMENTS [02-09-2024(online)].pdf	2024-09-02
2	202447066226-NOTIFICATION OF INT. APPLN. NO. & FILING DATE (PCT-RO-105-PCT Pamphlet) [02-09-2024(online)].pdf	2024-09-02
3	202447066226-FORM 1 [02-09-2024(online)].pdf	2024-09-02
4	202447066226-COMPLETE SPECIFICATION [02-09-2024(online)].pdf	2024-09-02
5	202447066226-CLAIMS UNDER RULE 1 (PROVISIO) OF RULE 20 [02-09-2024(online)].pdf	2024-09-02
6	202447066226-FORM-5 [03-09-2024(online)].pdf	2024-09-03
7	202447066226-FORM 3 [03-09-2024(online)].pdf	2024-09-03
8	202447066226-FORM 18 [03-09-2024(online)].pdf	2024-09-03
9	202447066226-Proof of Right [27-11-2024(online)].pdf	2024-11-27
10	202447066226-FORM 3 [09-12-2024(online)].pdf	2024-12-09