6 O Substituted Macrolides Having Antibacterial Activity

Abstract: The instant invention provides novel macrolide compounds and compositions useful in treating bacterial infections. Also provided are processes for preparing same. These macrolides are substituted on the 6-O-position with X'-Y'-Z', wherein X' is selected from the group consisting of C1-C10 alkyl, C3-C10 alkenyl, and C3-C10 alkynyl; Y' and Z' are independently selected from the group consisting of: (c) optionally substituted aryl, and (d) optionally substituted heteroaryl, with the proviso that both Y' and Z' are not both phenyl, and with the further proviso that Y' is not isoxazole when Z' is thiophenyl.

Patent Information

Application #

Filing Date

01 August 2001

Publication Number

36/2007

Publication Type

INA

Invention Field

PHARMACEUTICALS

Status

Email

Parent Application

Applicants

ABBOTT LABORATORIES

100 Abbott Park Road, Abbott Park, IL 60064-6050,

Inventors

1. OR, YAT, SUN

225 Walden Street, Cambridge, MA 02140

2. CLARK, Richard, F.

425 Hillside Drive, Mundelein, IL 60060

3. MA, Zhenkun

7193 Presidential Drive, Gurnee, IL 60031

4. RUPP, Michael, J.

Apartment 3V, 600 W. Washington Avenue, Lake Bluff, IL 60044

Specification

Documents

Application Documents

#	Name	Date
1	in-pct-2001-00926-mum-wo international publication report(1-8-2001).pdf	2018-08-08
2	IN-PCT-2001-00926-MUM-PUBLICATION REPORT(12-3-2009).pdf	2018-08-08
3	in-pct-2001-00926-mum-form 19(17-5-2004).pdf	2018-08-08
4	IN-PCT-2001-00926-MUM-CORRESPONDENCE(IPO).pdf	2018-08-08
5	in-pct-2001-00926-mum-correspondence(ipo)-(26-3-2009).pdf	2018-08-08
6	IN-PCT-2001-00926-MUM-CORRESPONDENCE(12-3-2009).pdf	2018-08-08
7	in-pct-2001-00926-mum-correspondence 2(10-5-2004).pdf	2018-08-08
8	in-pct-2001-00926-mum-correspondence 1(10-2-2009).pdf	2018-08-08