DESC:TECHNICAL FIELD
[0001] The present disclosure relates generally to the field of medical diagnostic equipment and devices, especially for utilization of signal transmission for the biomedical diagnostic In particular, the present disclosure relates to a system and a method for a biomedical diagnostic.

BACKGROUND
[0002] The following description includes information that may be useful in understanding the present invention. It is not an admission that any of the information provided herein is prior art or relevant to the presently claimed invention, or that any publication specifically or implicitly referenced is prior art.
[0003] As conventionally known in the art, medical procedures, like endoscopy, etc., are generally performed on a patient for screening and treatment of gastrointestinal (GI) tract-related diseases. This may involve the implantation of the intra-fluidtric balloon, observing and photographing tissue, taking a biopsy, and the activation of hemostasis. In the conventional method, an endoscopy is introduced into a patient through the mouth or colon. Such procedures require sedation and could induce abdominal pain and distention to the patient.
[0004] Therefore, non-invasive treatments and investigation of the GI tracts can increase the willingness of the patients to undergo regular disease screening, enhance their clinical experience, and resolve the problem of discomfort during endoscopy-like medical examinations. Recently, a therapeutic wireless capsule endoscopy (WCE) system has been introduced to provide endoscopic images from the intestines for diagnosis and treatment of GI tract-related diseases, therefore enabling the non-invasive examination of the GI tracts.
[0005] Further, the problem with current biomedical diagnostic systems being used that employ skin surface readings is that the electrical signals associated with abdominal muscular activity are hard to distinguish from electrical signals indicative of muscular activity of the gastrointestinal system. Therefore, what is needed is a system and method for accurately reading and detecting electrical signals from the capsule or the pill.
[0006] Additionally, methods such as: measuring variations in magnitudes of particular peaks as a function of the location of the pill, measuring variations in the slope of the exponential profile as a function of the location of the pill, computing a change in the RMS voltage of the signal received as a function of location of the pill, etc. are also valid yet tedious in implementation and more prone to being affected by noise.
[0007] While there has been development in the field of such medical devices or systems or methods for non-invasive diagnosis, however, there is still a need and scope for providing an improved and portable solution model, device, system, or method beyond for tracking a biomedical diagnostic device. Therefore, there is a dire need in the art to provide a system and method for biomedical diagnostic of the body of the user.
[0008] All publications herein are incorporated by reference to the same extent as if each individual publication or patent application were specifically and individually indicated to be incorporated by reference. Where a definition or use of a term in an incorporated reference is inconsistent or contrary to the definition of that term provided herein, the definition of that term provided herein applies and the definition of that term in the reference does not apply.

OBJECTS OF THE INVENTION
[0009] Some of the objects of the present disclosure, which at least one embodiment herein satisfies are as listed herein below.
[00010] It is an object of the present disclosure is to provide a system and method that obviates the above-mentioned limitations of the existing systems for the biomedical diagnostic.
[00011] It is another object of the present disclosure to provide a biomedical diagnostic device to be consumed by a human for non-invasive biomedical diagnosis.
[00012] It is another object of the present disclosure to provide a system for biomedical diagnostics with the processor as a signal processing unit for data acquisition and processing for a real-time location of the ingestible biomedical diagnostic device inside a human body.
[00013] It is yet another object of the present disclosure to provide a system and a method for the biomedical diagnostic device with a tracker belt for powering the ingestible biomedical diagnostic device (iBDD).
[00014] These and other objects of the present invention will become readily apparent from the following detailed description taken in conjunction with the accompanying drawings.

SUMMARY
[00015] The present disclosure relates generally to the field of medical diagnostic equipment and devices, especially for utilization with a signal transmission from within a human body. In particular, the present disclosure relates to the ingestible biomedical diagnostic device, and a system and a method for biomedical diagnostics.
[00016] An aspect of the present disclosure pertains to a system for biomedical diagnostic and a method thereof. The system includes an ingestible biomedical diagnostic device comprising a pulse sensing coil, a tracker belt comprising a pulse generation coil, and a receiver apparatus comprising a processor. The tracker belt generates pulses which are received by the diagnostic device to generate modulated signals. The receiver apparatus receives and analyzes the modulated signals to perform biomedical diagnostics. The diagnostic device further comprises an inductive coil, sensors, and a load. The system enables non-invasive and real-time monitoring of physiological parameters within the body. The receiver apparatus is an electronic device.
[00017] Various objects, features, aspects, and advantages of the inventive subject matter will become more apparent from the following detailed description of preferred embodiments, along with the accompanying drawing figures in which like numerals represent like components.

BRIEF DESCRIPTION OF THE DRAWINGS
[00018] In the figures, similar components and/or features may have the same reference label. Further, various components of the same type may be distinguished by following the reference label with a second label that distinguishes among the similar components. If only the first reference label is used in the specification, the description is applicable to any one of the similar components having the same first reference label irrespective of the second reference label.
[00019] FIG. 1 illustrates an exemplary block diagram of the proposed system to perform a biomedical diagnostic of the body of the user (FIG. 1), in accordance with exemplary embodiments of the present disclosure.
[00020] FIGs. 2 (A-B) illustrates a block architecture of the proposed system to perform biomedical diagnostic of the body of the user, to illustrate its overall working, in accordance with an embodiment of the present disclosure.
[00021] FIGs. 3 (A-K) illustrates an exemplary overview of the ingestible biomedical diagnostic device (iBDD), in accordance with exemplary embodiments of the present disclosure.
[00022] FIGs. 4 (A-B) illustrates an exemplary overview of a driver circuit associated with the proposed system for biomedical diagnostic of the user’s body, and a resonant circuit (a LC tank) associated with the proposed system for biomedical diagnostic, in accordance with an embodiment of the present disclosure.
[00023] FIGs. 5 (A-B) illustrates a block diagram for a receiver coil associated with the proposed system for biomedical diagnostic (FIG. 5A) and the block diagram for the receiver coil associated with the proposed system for biomedical diagnostic (FIG. 5B), in accordance with an embodiment of the present disclosure.
[00024] FIG. 6 illustrates a flow diagram depicting the proposed method 600 for performing biomedical diagnostics, in accordance with an embodiment of the present disclosure.

DETAILED DESCRIPTION
[00025] In the following description, numerous specific details are set forth in order to provide a thorough understanding of embodiments of the present invention. It will be apparent to one skilled in the art that embodiments of the present invention may be practiced without some of these specific details.
[00026] If the specification states a component or feature “may”, “can”, “could”, or “might” be included or have a characteristic, that particular component or feature is not required to be included or have the characteristic.
[00027] Embodiments of the present disclosure pertain generally to the field of medical diagnostic equipment and devices, especially for utilization with a signal transmission from within the user’s body. In particular, the present disclosure relates to a biomedical diagnostic device, and a system and a method for biomedical diagnostic of the body of the user.
[00028] FIG. 1 illustrates an exemplary block diagram of the proposed system to perform biomedical diagnostic of the body of the user (FIG. 1), in accordance with exemplary embodiments of the present disclosure.
[00029] The present disclosure describes a system 100 for biomedical diagnostics. The system 100 comprises an ingestible biomedical diagnostic device ( hereinafter “iBDD”) 102, a tracker belt 108, and a receiver apparatus 104.
[00030] The iBDD 102 is a device designed to be swallowed by a user for the purpose of biomedical diagnosis. The iBDD 102 is preferably small and lightweight to facilitate ingestion. It is made of an edible material or a bioabsorbable material, ensuring safe passage through the digestive system and eventual breakdown or absorption by the body. One embodiment of the iBDD 102 can be a pill form factor constructed from a gelatin capsule enclosing a sugar core.
[00031] The iBDD 102 has a pulse sensing coil 102-1. The coil 102-1 is utilised to receive pulses generated by the tracker belt 108. Upon receiving the pulses, the iBDD 102 generates one or more modulated signals. The iBDD 102 may include one or more enclosed sensors 102-3 to measure specific physiological parameters within the body of the user. The sensors 102-3 can be powered by an inductive coil 102-2 present within the iBDD 102. The inductive coil receives power wirelessly from the tracker belt 108.
[00032] A load 102-4 is connected to the inductive coil 102-2 within the iBDD 102 to manage the received power. The load 102-4 can be a simple short circuit, allowing all induced current to flow freely. Alternatively, a diode can be used to regulate the current flow and potentially improve efficiency. Yet another embodiment utilizes a pH sensor as the load 102-4. The pH sensor would measure the acidity level within the digestive system of the user, and the sensed data could be used in conjunction with the modulated signals for diagnostic purposes.
[00033] The tracker belt 108 is a wearable device typically positioned around the waist of the user. It houses a pulse generation coil 108-1 that transmits one or more pulses towards the iBDD 102 within the user's body. The pulses interact with the pulse sensing coil 102-1 of the iBDD 102, enabling communication and data transmission.
[00034] The receiver apparatus 104 is a device configured to communicate with the iBDD 102. It comprises one or more processors capable of receiving the modulated signals generated by the iBDD 102. These processors analyse the received signals to identify variations. Based on the determined variations within the modulated signals, the receiver apparatus 104 performs the desired biomedical diagnosis. In an embodiment, the receiver apparatus 104 is an electronic device.
[00035] The specific type of biomedical diagnosis performed by the system 100 can be tailored based on the chosen sensors within the iBDD 102 and the analysis algorithms implemented within the receiver apparatus 104.
[00036] In a nutshell, the present invention provides the system 100 for biomedical diagnostics, including the functionalities of the iBDD 102, tracker belt 108, and receiver apparatus 104. The provided embodiments with reference to FIG. 1 illustrate potential implementations of the system's components.
[00037] In an embodiment, the iBDD 102 comprises one or more coils insulated from each other and mutually perpendicular to each other, wherein each coil is made of a material selected from Copper, Aluminium, or Silver, or each coil is made of a different material from each other.
[00038] In these embodiments, the driver circuit 108-2 has a single-phase full bridge diode rectifier; and a resonant circuit (a LC Tank) 108-3 has an inductor and capacitor bank in series.
[00039] In these embodiments, the receiver coil 106 is positioned parallel to the pulse generation coil 108-1, the processor 104-1 is a signal processing unit having analog and digital subsystems to obtain a resolution on the location of the iBDD 102, and a display unit 110 to display a real-time location of the iBDD 102 on a user interface of the receiver apparatus 104.
[00040] FIGs. 2 (A-B) illustrates a block architecture (200a, 200b) of the proposed system 100 to perform a biomedical diagnostic of the body of the user, to illustrate its overall working, in accordance with an embodiment of the present disclosure.
[00041] A block architecture of the proposed system 100 (interchangeably, also termed as system 100, herein) for biomedical diagnostic using the ingestible biomedical diagnostic device (iBDD) is depicted in FIGs. 2 (A-B) to illustrate its overall working, in accordance with an embodiment of the present disclosure.
[00042] In an exemplary embodiment of the present disclosure, the system 100 may include the biomedical diagnostic device 102, a driver circuit 108-2, a receiver coil 106, a processor 104-1, and a display unit 110. The driver circuit 108-2, the receiver coil 106, the processor 104-1 and the display unit 110 may together constitute a receiver apparatus. The system 100 may also comprise a tracker belt configured to be mounted onto the waist of the user/human. The biomedical diagnostic device 102 may be ingestible and made of edible materials. The receiver apparatus 104 may be a hand-held equipment that may be placed around the stomach region of the user to pick up the signals. The processor 104-1 may receive and process the picked-up signals and show a real-time location of the biomedical diagnostic device 102 inside the body of the user, i.e., the human body.
[00043] The tracker belt impinges pulses onto the stomach area of the user. The biomedical diagnostic device 102 or the iBDD 102 may pick up these pulses. The biomedical diagnostic device 102 as an exemplary sub-system may further modulate the picked-up pulses almost instantaneously. The variations induced in the pulses may be picked up by the receiver coil 106 when placed around the stomach region of the user.
[00044] Referring to FIG.2B, at block 120, the ingestible biomedical diagnostic device (iBDD) 102, being ingested by the user, may be able to send and receive the signals from the system 100. At block 130, the primary pulses may be generated and forwarded to block 140 for processing by a sensitive receiver coil or circuitry. Then, at block 150, high-resolution data acquisition and processing may be performed by the system 100 or the processor 104-1.
[00045] FIGs. 3 (A-K) illustrates an exemplary overview of the ingestible biomedical diagnostic device (iBDD) 102, in accordance with exemplary embodiments of the present disclosure.
[00046] Referring to FIGs. 3 (A-K), an ingestible biomedical diagnostic device (iBDD) 102 is illustrated, in accordance with exemplary embodiments of the present disclosure. The iBDD 102 may be an edible capsule or a pill and may be made up of bio-absorbable material which is safe to ingest with all the constituent materials used within the daily intake limit. The iBDD 102 may house an inductive coil 102-2 which powers the necessary sensors to bring out a detectable change in signal modulation at the primary side and at least a load 102-4 connected to the inductive coil. The load 102-4 may be a simple circuit or a diode to induce a non-linearity or a pH sensor depending on the application.
[00047] In an aspect of the present disclosure, the entirety of the iBDD 102 may structurally be split into 2 parts - a gelatine capsule and a sugar core. The gelatine capsule is meant to house payloads like a plurality of sensors for sensing various signals and/or medical conditions, wherein the plurality of sensors may include image sensors, audio sensors, or the like. The sugar core may surround the gelatine capsule and facilitate in mechanical stability to the sensor payload and surface for pulse sensing coil 102-1. The pulse sensing coil 102-1 may interact with the tracker belt coil through mutual induction. The maximum interaction between the tracker belt coil and the pulse sensing coil 102-1 may occur when the axes are parallel to each other. When an iBDD 102 enters the GI tract of the user, the orientation of the pulse sensing coil 102-1 axis is not controllable and not observable. Thus, to maximize interaction between the tracker belt coil and the pulse sensing coil 102-1, an omnidirectional coil may be utilized. This may be achieved by having three separate coils insulated from each other and mutually perpendicular to each other. The coils may be made of different materials like copper, aluminium, silver or the like to accommodate the electrical requirements while adhering to the edibility constraints of the iBDD 102. The tracker belt may be considered as the key for powering the iBDD 102, wherein the tracker belt may comprise of a driver circuit 108-2 and a resonant circuit (a LC tank) 108-3.
[00048] FIGs. 4 (A-B) illustrates an exemplary overview (400A, 400B) of a driver circuit 108-2 associated with the proposed system 100 for biomedical diagnostic of the user’s body, and a a resonant circuit (a LC tank) 108-3 associated with the proposed system 100 for biomedical diagnostic, in accordance with an embodiment of the present disclosure.
[00049] Now, referring to FIG. 4A, a driver circuit 108-2 associated with the proposed system 100 for the biomedical diagnostic is illustrated, in accordance with an embodiment of the present disclosure. The driver circuit 108-2 (as shown in FIG. 4A) may be connected to any household mains supply directly or through a single-phase variac in a commercial setting.
[00050] The driver circuit 108-2 may comprise a single-phase full bridge diode rectifier. The output of the bridge diode rectifier may be connected to a DC bus (for e.g., large DC capacitors, etc.). A voltage sensor may further provide a real-time feed of the DC bus voltage. The main power contactor may be kept in the ON state for as long as the DC bus voltage is not at a preset voltage, otherwise, the main power contactor may be kept in the OFF state.
[00051] A resonant circuit (LC tank)’s load may be connected to the DC bus. A switch (also, referred to as Measure MOS switch, herein) may be connected in series to the resonant circuit (LC tank) load. A discharge relay circuit may be connected in parallel to a capacitor bank of the LC tank load. A dedicated microcontroller (µC) may be programmed to generate a PWM scheme (as shown in FIG. 4B) to control the switching of both the measure MOS switch and a discharge relay. The PWM scheme may operate the driver circuit 108-2 in two modes, a pulse-gen mode and a discharge mode.
[00052] The discharge relay arrangement may be considered critical to the generation of oscillations, i.e. it ensures the discharge of the capacitor bank in the discharge mode before the start of every pulse-gen mode.
[00053] Referring to FIG. 4B, a resonant circuit (LC tank) 108-3 associated with the proposed system 100 for the biomedical diagnostic is illustrated, in accordance with an embodiment of the present disclosure.
[00054] The resonant circuit (LC tank) 108-3 or load 300b may comprise of an inductor and capacitor bank in series. The inductor may be mounted on an acrylic-based belt. The capacitor bank may consist of ceramic capacitors. ON pulse to the gate of the Measure MOS switch ensures its turned ON, thereby, exciting the resonant circuit (LC tank) 108-3 load by the output voltage of the driver circuit 300a i.e., nearly a DC excitation. Theoretically, a resonant circuit (LC tank) 108-3 on DC excitation draws an oscillating current. The presence of parasitic resistances damps the oscillations following an exponentially decaying envelope.
[00055] Mathematically,
(1)
[00056] On differentiating the equation (1) w.r.t time, equation (2) can be received as:
(2)
[00057] On solving the second order differential equation (2), equation (3) can be received as:
(3)
[00058] where, i1and i2 are arbitrary constants, and s1and s2 can be given as:


[00059] On incorporating the initial conditions of the system, the expression for current to be can be given as:
(4)
[00060] For sustained oscillations,
[00061] Further, the iBDD 102 energisation may be wireless and based on the phenomenon of mutual induction between the iBDD 102 and the tracker belt 108. This requires a magnetic flux density to be established by the tracker belt 108 and can be mathematically formulated as:
(at the center of the coil)
[00062] So, the design constraints for the tracker belt may be as: a) A sufficiently large Lcoil can be necessary to establish magnetic flux density within the safe exposure limit. b) Cbank should be appropriately low in magnitude to generate sustained oscillations yet high enough to filter out harmonics in inductor current to have sinusoidal oscillations only of the tank resonant frequency.
[00063] FIGs. 5 (A-B) illustrates a block diagram 500a for a receiver coil 106 associated with the proposed system 100 for biomedical diagnostic (FIG. 5A) and block diagram 500b of the receiver coil 106 associated with the proposed system 100 for biomedical diagnostic (FIG. 5B), in accordance with an embodiment of the present disclosure
[00064] Referring to FIGs. 5A and 5B, a block diagram 500a for a receiver coil 106 and the receiver coil 106 associated with the proposed system 100 for the biomedical diagnostic is depicted, in accordance with an embodiment of the present disclosure. As discussed with reference to FIG. 1, the receiver apparatus 104 being a hand-held device may comprise of the receiver coil 106, the processor 104-1, and the display unit 110.
[00065] The axis of the receiver coil 106 and the pulse generation coil 108-1 are to be parallel to maximise the EMF (electromotive force) induced in the receiver coil 106. The number of turns and distance between the tracker belt 108 and the receiver coil 106 primarily govern the sensitivity of the receiver coil 106.
[00066] The processor 104-1 may comprise of both analog and digital subsystems for efficient processing. The strategy of processing the input signal to obtain a resolution on the location of the iBDD 102 may be as follows:
[00067] The driver circuit (104, 300a) may put out a sinusoidal signal of a frequency that may be decided by the inductor (tracker belt coil) and the capacitor or the capacitor bank used. Further, when the iBDD 102 (and therefore the pulse sensing coil 102-1) is present in the vicinity of the tracker belt the tracker, it can electrically load the tracker belt coil since the pulse sensing coil 102-1 is essentially a short circuit. This, therefore, changes the waveform in the tracker belt coil which can then be sensed.
[00068] Now, if the pulse generation coil 108-1 and the pulse sensing coil 102-1 can be modeled or imagined to be the primary and secondary coils of a transformer (with the air, body tissue etc. forming the core). The secondary coil (i.e., the pulse sensing coil 102-1) can be seen as a short-circuit load. Practically, the secondary coil has a low but non-zero resistive load that depends on the self-resistance of the pulse-sensing coil 102-1. When the iBDD 102 is far away from the tracker belt 108, the effective turns ratio of this transformer model is large and the effective resistance of the pulse sensing coil 102-1 reflected back to the primary is large. Therefore, the waveform in the primary, i.e. in the tracker belt coil decays rapidly. When the iBDD 102 is in the proximity of the tracker belt, the effective resistance of the pulse sensing coil 102-1 reflected back to the primary is small. Therefore, the waveform in the primary, i.e. in the pulse generation coil 108-1 decays slowly. It is this change in decay rate that estimates the position of the pulse sensing coil 102-1 with respect to the tracker belt 108.
[00069] The purpose of the processor 104-1 is to identify this change in decay rate and provide the analog or digital signal that is indicative of the position of the iBDD 102 with respect to the tracker belt 108. For this purpose, the processor 104-1 has a receiver coil 106 placed outside the body and adjacent to the pulse generation coil 108-1, and in plane with the pulse generation coil 108-1. The voltage waveform across the receiver coil 106 is processed to locate the iBDD102.
[00070] Since the pulse generation coil 108-1 sends out a sinusoidal waveform burst, the input to processor 104-1 for each burst can be a sinusoidal ringing signal riding over an exponentially decaying profile. The information on the location of the iBDD 102 lies in the decay rate. Therefore, when the pulse sensing coil 102-1 is in the proximity of the pulse generation coil 108-1, one or more waves (rings) are expected to be received due to the lower decay rate as opposed to the case when the iBDD 102 is far from the tracker belt 108. The processor 104-1 therefore needs to process the signal such that these last few waves of low amplitude are captured. Further, the output of this stage may be fed as an input to the integrator stage. The integrator may be designed to hold the volt-sec value of a particular pulse until the next pulse arrives. As the next pulse arrives, the integrator is reset i.e., the held value is cleared. This facilitates a method to lock on to the most sensitive pulses of the pulse train i.e., the last two pulses. The reset signal may be generated by digital logic implemented using universal gates. The final integrator value of each pulse train may then be fed to the control unit or the microcontroller of the system 100.
[00071] An onboard analog-to-digital (A/D) converter may be operated at a sampling frequency such that only the final value of the integrator can be stored in a register for comparison with integration values of subsequent pulses. The difference value may then be matched with entries in a look-up for correspondence to the real-time location of the iBDD 102. The real-time location of the iBDD 102 may then be conveyed to the user on a display unit 110.
[00072] FIG. 6 illustrates a flow diagram depicting the proposed method 600 for performing a biomedical diagnostic, in accordance with an embodiment of the present disclosure.The method 200 comprises a series of steps executed by a user and the system 100.
[00073] At block 602, the method commences with the user ingesting the ingestible biomedical diagnostic device (iBDD) 102 (Figure 1, 102). As described previously, the iBDD 102 is designed to be safe for swallowing and contains the necessary components for communication with the tracker belt 108.
[00074] At block 604, The user then wears the tracker belt 108 (Figure 1, 103) around their waist. The tracker belt 108 houses the pulse generation coil 108-1 and other electronic components to communicate with the ingested iBDD 102. The tracker belt 108 generates one or more pulses using the pulse generation coil 108-1. The pulses travel wirelessly within the user's body and are received by the pulse sensing coil within the iBDD 102 . The iBDD 102 then generates one or more modulated signals in response to the received pulses.
[00075] At block 606, the receiver apparatus 104, which is communicably coupled with the iBDD 102, receives the generated modulated signals. The receiver apparatus 104 employs the processor 104-1 to analyse these signals and identify variations within them.
[00076] At block 608, based on the determined variations present in the received modulated signals, the receiver apparatus 104 performs the desired biomedical diagnosis. The specific type of diagnosis will depend on the functionalities of the iBDD 102 and sensor types and the analytical algorithms implemented within the receiver apparatus 104.
[00077] The method 600 further includes the tracker belt 108 and receiver apparatus 104. The tracker belt 108 comprises a driver circuit with a single-phase full bridge diode rectifier, which helps manage the power supply. Additionally, a resonant circuit (LC tank) 108-3 comprising an inductor and capacitor bank connected in series can be incorporated to optimize the generated pulses.
[00078] The receiver apparatus 104 may include a coil positioned parallel to the pulse generation coil 108-1 of the tracker belt 108 to enhance signal reception. The processor 104-1 within the receiver apparatus 104 can be embodied as a signal processing unit with both analog and digital subsystems. This allows for processing of the received signals with high resolution, aiding in the determination of the iBDD 102's location within the body. Finally, a display unit 110 can be integrated into the receiver apparatus 104 to provide a real-time visual representation of the iBDD 102's location on a user interface.
[00079] The iBDD 102 comprises multiple coils that are electrically insulated from each other and positioned perpendicularly (at right angles) to each other. The coils can be made from various conductive materials such as copper, aluminum, or silver. Alternatively, each coil can be constructed from a different conductive material for potentially improved performance. In another embodiment, the method 600 can be implemented in various ways without deviating from the concept of the present invention.
[00080] Another aspect of the present disclosure pertains to the method 600 may initiate the signal processing by converting the received signal into a pulse train using a zero-reference comparator. The output of the comparator may swing from rail to rail across a bipolar voltage supply. The corrections for drift, offset, and desensitisation with respect to power supply variations may be accounted for. The bipolar pulse train may be converted to a unipolar, digital domain-compatible signal at the level shifter stage.
[00081] Another embodiment of the present disclosure pertains to the method 600 for tracking a biomedical diagnostic device 102. The method 600 may comprise the steps of: at step 1, receiving, at a processor 104-1, from a biomedical diagnostic device 102, using a driver circuit 108-2 and a receiver coil circuit 106, a signal relative to a real-time location of the biomedical diagnostic device 102 inside the human body; at step 2, converting, at the processor 104-1, using a zero reference comparator, the received signal into a pulse train; at step 3, comparing, at the processor 104-1, using an integrator, a pre-defined value of the integrator with a plurality of integration values of each pulse among the pulse train to obtain a difference value; at step 4, matching, at the processor 104-1, the difference value with a plurality of preset difference values in a look up database for correspondence to the biomedical diagnostic device 102 location; and at step 5, displaying, by the processor 104-1, at a display unit 110, a real-time location of the biomedical diagnostic device 102 inside the human body based on a successful matching of the difference value with the plurality of preset difference values.
[00082] While the foregoing describes various embodiments of the invention, other or further embodiments of the invention may be devised without departing from the basic scope thereof. The scope of the invention is determined by the claims that follow. The invention is not limited to the described embodiments, versions or examples, which are included to enable a person with ordinary skill in the art to make and use the invention when combined with information or knowledge available to the person with ordinary skill in the art.

ADVANTAGES OF THE INVENTION:
[00083] The present disclosure provides a system and a method that obviates the above-mentioned limitations of the existing biomedical diagnostic systems or methods.
[00084] The present disclosure provides a system that uses a non-invasive biomedical diagnostic technology.
[00085] The present disclosure provides an ingestible biomedical diagnostic device to be consumed by a human for non-invasive biomedical diagnostic.
[00086] The present disclosure provides a system and a method that detects the variations induced in the pulses that are picked up by the receiver coil when placed around the stomach region.
[00087] The present disclosure provides a system and a method for performing a biomedical diagnostic with the help of the tracker belt to obtain a resolution on the real-time location of the ingestible biomedical diagnostic device (iBDD) on a display unit.
,CLAIMS:1. A system (100) for biomedical diagnostic, the system (100) comprising:
an ingestible biomedical diagnostic device (iBDD) (102) being ingestible by a user, wherein the iBDD102 comprises a pulse sensing coil (102-1);
a tracker belt (108) communicably coupled to the iBDD (102), wherein the tracker belt (108) is wearable around a waist of the user, and the tracker belt (108) comprises a pulse generation coil (108-1) adapted to generate one or more pulses such that the pulse sensing coil (102-1) of the iBDD (102) ingested by the used receives the one or more generated pulses to thereby generate one or more modulated signals;
a receiver apparatus (104) communicably coupled to the iBDD (102), the receiver apparatus (104) comprises a processor (104-1) configured to:
receive the one or more generated modulated signals; and
determine a variation present in the one or more received modulated signals to thereby perform the biomedical diagnostic based on the determined variation.
2. The system (100) as claimed in claim 1, wherein the iBDD (102) is a pill made of an edible material or a bioabsorbable material, and the iBDD (102) comprises gelatine capsule enclosed inside sugar core.
3. The system (100) as claimed in claim 1, wherein the iBDD (102) comprises:
an inductive coil (102-2) that powers one or more enclosed sensors (102-3) to obtain a detectable change in the one or more generated modulated signals at the primary side; and
a load (102-4) connected to the inductive coil (102-2), wherein the load (102-4) is a short circuit, or a diode, or a pH sensor.
4. The system (100) as claimed in claim 1, wherein the iBDD (102) comprises one or more coils insulated from each other and mutually perpendicular to each other, wherein each coil is made of a material selected from Copper, Aluminium, Silver, or each coil is made of a different material from each other.
5. The system (100) as claimed in claim 1, wherein the receiver apparatus (104) is an electronic device.
6. The system (100) as claimed in claim 1, wherein the tracker belt (108) comprises:
a driver circuit (108-2) having a single-phase full bridge diode rectifier; and
a resonant circuit (a LC Tank) (108-3) having an inductor and capacitor bank in series.
7. The system (100) as claimed in claim 1, wherein the receiver apparatus (104) comprises:
a receiver coil (106) positioned parallel to the pulse generation coil (108-1);
the processor (104-1) is a signal processing unit having analog and digital subsystems to obtain a resolution on the location of the iBDD (102); and
a display unit (110) to display a real-time location of the iBDD (102) on a user interface of the receiver apparatus (104).
8. A method (600) for performing biomedical diagnostic, the method (600) comprising:
ingesting (602) an ingestible biomedical diagnostic device (iBDD) (102) by the user, wherein the iBDD (102) comprises a pulse sensing coil (102-1);
wearing (604) a tracker belt (108) around a waist of the user, wherein the tracker belt (108) is communicably coupled to the iBDD (102) and the tracker belt (108) comprises a pulse generation coil (108-1) adapted to generate one or more pulses such that the pulse sensing coil (102-1) of the iBDD (102) ingested by the used receives the one or more generated pulses to thereby generate one or more modulated signals;
receiving (606), through a processor (104-1) of a receiver apparatus (104), the one or more generated modulated signals, wherein the receiver apparatus (104) communicably coupled to the iBDD (102); and
determining (608), through the processor (104-1) of the receiver apparatus (104), a variation present in the one or more received modulated signals to thereby perform the biomedical diagnostic based on the determined variation.
9. The method (600) as claimed in claim 8, wherein:
the tracker belt (108) comprises:
a driver circuit (108-2) having a single-phase full bridge diode rectifier; and
a resonant circuit (a LC Tank) (108-3) having an inductor and capacitor bank in series; and
the receiver apparatus (104) comprises:
a receiver coil (106) positioned parallel to the pulse generation coil (108-1);
the processor (104-1) is a signal processing unit having analog and digital subsystems to obtain a resolution on the location of the iBDD (102); and
a display unit (110) to display a real-time location of the iBDD (102) on a user interface of the receiver apparatus (104).
10. The method 200 as claimed in claim 8, wherein the iBDD (102) comprises one or more coils insulated from each other and mutually perpendicular to each other, wherein each coil is made of a material selected from Copper, Aluminium, Silver, or each coil is made of a different material from each other.