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A Composite Drug Polymer Nano Complex And Method For Making The Same
Abstract: Prolonged delivery of chemodrugs locally inside the brain with sufficient tissue–penetration is a critical requirement for treating various brain-diseases including malignant tumors. The present disclosure relates to an injectable microparticle system for brain- drug delivery. The injectable microparticle system comprising drug-loaded polymeric microparticles, wherein the drug-loaded polymeric microparticles are coated with an outer polymer gel layer enabling in-situ formation and releasing drug-polymer nanocomplexes of size < 100nm. The injectable microparticle system facilitates both deep tissue penetration for > 2cm as well as ’sustained release’ of the drug for 15-30 days. The invention also discloses a method of producing said injectable microparticle system and the use of said injectable microparticle system in the treatment of brain tumor and other cancers.
Notices, Deadlines & Correspondence
Patent Information
Applicants
AMRITA VISHWA VIDYAPEETHAM
Inventors
1. MANZOOR KOYAKUTTY
2. DEVIKA DAS
3. DHANYA NARAYANAN
4. RANJITH RAMACHANDRAN
5. SHANTIKUMAR NAIR
Specification
DESC:PLEASE SEE ATTACHED ,CLAIMS:PLEASE SEE ATTACHED
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 202241038701-STATEMENT OF UNDERTAKING (FORM 3) [05-07-2022(online)].pdf | 2022-07-05 |
| 2 | 202241038701-PROVISIONAL SPECIFICATION [05-07-2022(online)].pdf | 2022-07-05 |
| 3 | 202241038701-POWER OF AUTHORITY [05-07-2022(online)].pdf | 2022-07-05 |
| 4 | 202241038701-FORM FOR SMALL ENTITY(FORM-28) [05-07-2022(online)].pdf | 2022-07-05 |
| 5 | 202241038701-FORM 1 [05-07-2022(online)].pdf | 2022-07-05 |
| 6 | 202241038701-EVIDENCE FOR REGISTRATION UNDER SSI(FORM-28) [05-07-2022(online)].pdf | 2022-07-05 |
| 7 | 202241038701-EDUCATIONAL INSTITUTION(S) [05-07-2022(online)].pdf | 2022-07-05 |
| 8 | 202241038701-DRAWINGS [05-07-2022(online)].pdf | 2022-07-05 |
| 9 | 202241038701-DECLARATION OF INVENTORSHIP (FORM 5) [05-07-2022(online)].pdf | 2022-07-05 |
| 10 | 202241038701-Proof of Right [12-07-2022(online)].pdf | 2022-07-12 |
| 11 | 202241038701-DRAWING [04-07-2023(online)].pdf | 2023-07-04 |
| 12 | 202241038701-CORRESPONDENCE-OTHERS [04-07-2023(online)].pdf | 2023-07-04 |
| 13 | 202241038701-COMPLETE SPECIFICATION [04-07-2023(online)].pdf | 2023-07-04 |
| 14 | 202241038701-FORM 18 [10-07-2023(online)].pdf | 2023-07-10 |
| 15 | 202241038701-ENDORSEMENT BY INVENTORS [10-07-2023(online)].pdf | 2023-07-10 |
| 16 | 202241038701-Proof of Right [11-07-2023(online)].pdf | 2023-07-11 |
| 17 | 202241038701-Request Letter-Correspondence [07-08-2023(online)].pdf | 2023-08-07 |
| 18 | 202241038701-Covering Letter [07-08-2023(online)].pdf | 2023-08-07 |
| 19 | 202241038701-CERTIFIED COPIES TRANSMISSION TO IB [07-08-2023(online)].pdf | 2023-08-07 |
| 20 | 202241038701-FER.pdf | 2025-07-18 |
| 21 | 202241038701-FORM 3 [17-09-2025(online)].pdf | 2025-09-17 |
Search Strategy
| 1 | 202241038701_SearchStrategyNew_E_SearchHistoryE_15-07-2025.pdf |