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A Composition Comprising A Flavanone, And Metabolite Thereof And Uses Thereof

Abstract: The present disclosure relates to a composition comprising naringin and naringenin for inhibiting intracellular cholesterol, and to maintain general health and wellbeing by guarding against excessive cholesterol in cells.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
11 April 2016
Publication Number
41/2017
Publication Type
INA
Invention Field
BIO-MEDICAL ENGINEERING
Status
Email
lsmds@lakshmisri.com
Parent Application

Applicants

ITC LIMITED
ITC LIFE SCIENCES & TECHNOLOGY CENTRE #3. 1ST MAIN, PEENYA INDUSTRIAL AREA, PHASE 1, BANGALORE 560 058, INDIA

Inventors

1. KUDTARKAR, Kavita Gopalkrishna
ITC LIFE SCIENCES & TECHNOLOGY CENTRE #3. 1ST MAIN, PEENYA INDUSTRIAL AREA, PHASE 1, BANGALORE 560 058, INDIA
2. KS, Nandakumar
ITC LIFE SCIENCES & TECHNOLOGY CENTRE #3. 1ST MAIN, PEENYA INDUSTRIAL AREA, PHASE 1, BANGALORE 560 058, INDIA
3. RADHAKRISHNAN, Yashwanth
ITC LIFE SCIENCES & TECHNOLOGY CENTRE #3. 1ST MAIN, PEENYA INDUSTRIAL AREA, PHASE 1, BANGALORE 560 058, INDIA
4. CHANDRASEKHARAN, Lakshmanan Chittur
ITC LIFE SCIENCES & TECHNOLOGY CENTRE #3. 1ST MAIN, PEENYA INDUSTRIAL AREA, PHASE 1, BANGALORE 560 058, INDIA

Specification

Claims:1. A composition comprising:
a. naringin; and
b. naringenin,
wherein naringin to naringenin w/w ratio in said composition is in the range of 1:0.5-1:5.
2. The composition as claimed in claim 1, wherein naringin weight percentage in said composition is in the range of 0.000025-0.0001%, and naringenin weight percentage in said composition is in the range of 0.00005-0.000125%.
3. The composition as claimed in claim 1, wherein naringin to naringenin w/w ratio in said composition is in the range of 1:0.66-1:4.
4. The composition as claimed in claim 3, wherein naringin weight percentage in said composition is in the range of 0.00003-0.00009%, and naringenin weight percentage in said composition is in the range of 0.00006-0.00012%.
5. The composition as claimed in claim 3, wherein naringin to naringenin w/w ratio in said composition is 1:0.66.
6. The composition as claimed in claim 5, wherein naringin weight percentage in said composition is 0.00009%, and naringenin weight percentage in said composition is 0.00006%.
7. The composition as claimed in claim 3, wherein naringin to naringenin w/w ratio in said composition is 1:1.
8. The composition as claimed in claim 7, wherein naringin weight percentage in said composition is 0.000075%, and naringenin weight percentage in said composition is 0.000075%.
9. The composition as claimed in claim 3, wherein naringin to naringenin w/w ratio in said composition is 1:1.5.
10. The composition as claimed in claim 9, wherein naringin weight percentage in said composition is 0.00006%, and naringenin weight percentage in said composition is 0.00009%.
11. The composition as claimed in claim 3, wherein naringin to naringenin w/w ratio in said composition is 1:4.
12. The composition as claimed in claim 11, wherein naringin weight percentage in said composition is 0.00003%, and naringenin weight percentage in said composition is 0.00012%.
13. The composition as claimed in any of the claims 1-12, further comprising carriers, diluents, and excipients.
14. A method of preparing a composition as claimed in any of the claims 1-13.
15. A method of inhibiting intracellular cholesterol, said method comprising:
a. obtaining a composition as claimed in any of the claims 1-13; and
b. contacting said composition with a cell comprising cholesterol,
wherein said method inhibits intracellular cholesterol.
Dated this April, 2016
, Description:As Attached

Documents

Application Documents

# Name Date
1 Form 5 [11-04-2016(online)].pdf 2016-04-11
2 Form 3 [11-04-2016(online)].pdf 2016-04-11
3 Drawing [11-04-2016(online)].pdf 2016-04-11
4 Description(Complete) [11-04-2016(online)].pdf 2016-04-11
5 Other Patent Document [26-05-2016(online)].pdf 2016-05-26
6 Form 26 [26-05-2016(online)].pdf 2016-05-26
7 201641012731-FORM 18 [09-04-2020(online)].pdf 2020-04-09
8 201641012731-FER.pdf 2021-10-17

Search Strategy

1 search201641012731E_22-09-2020.pdf