Abstract: The present disclosure provides a combination of adenosine triphosphate and gluconolactone for promoting wound healing at particular weight ratio combinations. Also provided are formulations comprising said composition, and patches for topical application to promote epithelial wound healing.
Claims:1. A composition comprising:
- adenosine triphosphate; and
- gluconolactone,
wherein adenosine triphosphate to gluconolactone w/w ratio in said composition is in the range of 2.5:1-40:1.
2. The composition as claimed in claim 1, wherein adenosine triphosphate to gluconolactone w/w ratio in said composition is 10:1.
3. The composition as claimed in claim 1, wherein adenosine triphosphate weight concentration in said composition is in the range of 0.05-0.2%, and gluconolactone weight concentration in said composition is in the range of 0.005-0.02%.
4. A method of preparing a composition as claimed in any of the claims 1-3.
5. A formulation comprising:
- adenosine triphosphate;
- gluconolactone; and
- suitable carriers, diluents, and excipients,
wherein adenosine triphosphate to gluconolactone w/w ratio in said formulation is in the range of 2.5:1-40:1.
6. The formulation as claimed in claim 5, wherein adenosine triphosphate to gluconolactone w/w ratio in said formulation is 10:1.
7. A method of preparing a formulation as claimed in any of the claims 5-6.
8. A method of promoting epithelial wound healing, said method comprising:
- obtaining a composition as claimed in any of the claims 1-3; and
- contacting said composition with site of epithelial wound,
wherein said method promotes epithelial wound healing.
9. A method of promoting epithelial wound healing, said method comprising:
- obtaining a formulation as claimed in any of the claims 5-6; and
- contacting said formulation with site of epithelial wound,
wherein said method promotes epithelial wound healing.
10. A patch for topical application for epithelial wound healing comprising a composition as claimed in any of the claims 1-3, further optionally comprising suitable carriers, diluents, and excipients.
11. A composition comprising a composition as claimed in any of the claims 1-3, or a formulation as claimed in any of the claims 5-6 for use in promoting epithelial wound healing.
, Description:As Attached
| Section | Controller | Decision Date |
|---|---|---|
| # | Name | Date |
|---|---|---|
| 1 | 5931-CHE-2015-IntimationOfGrant20-10-2023.pdf | 2023-10-20 |
| 1 | Sequence listing [02-11-2015(online)].pdf | 2015-11-02 |
| 2 | 5931-CHE-2015-PatentCertificate20-10-2023.pdf | 2023-10-20 |
| 2 | Form 5 [02-11-2015(online)].pdf | 2015-11-02 |
| 3 | Form 3 [02-11-2015(online)].pdf | 2015-11-02 |
| 3 | 5931-CHE-2015-Written submissions and relevant documents [19-10-2023(online)].pdf | 2023-10-19 |
| 4 | Drawing [02-11-2015(online)].pdf | 2015-11-02 |
| 4 | 5931-CHE-2015-FORM-26 [04-10-2023(online)].pdf | 2023-10-04 |
| 5 | Description(Complete) [02-11-2015(online)].pdf | 2015-11-02 |
| 5 | 5931-CHE-2015-Correspondence to notify the Controller [03-10-2023(online)].pdf | 2023-10-03 |
| 6 | 5931-CHE-2015-US(14)-HearingNotice-(HearingDate-05-10-2023).pdf | 2023-09-05 |
| 6 | 5931-CHE-2015-Power of Attorney-050116.pdf | 2016-06-16 |
| 7 | 5931-CHE-2015-Form 1-050116.pdf | 2016-06-16 |
| 7 | 5931-CHE-2015-CLAIMS [04-11-2022(online)].pdf | 2022-11-04 |
| 8 | 5931-CHE-2015-FER_SER_REPLY [04-11-2022(online)].pdf | 2022-11-04 |
| 8 | 5931-CHE-2015-Correspondence-F1-PA-050116.pdf | 2016-06-16 |
| 9 | 5931-CHE-2015-FORM 18 [27-09-2019(online)].pdf | 2019-09-27 |
| 9 | 5931-CHE-2015-SEQUENCE LISTING [04-11-2022(online)].txt | 2022-11-04 |
| 10 | 5931-CHE-2015-FER.pdf | 2022-05-04 |
| 11 | 5931-CHE-2015-FORM 18 [27-09-2019(online)].pdf | 2019-09-27 |
| 11 | 5931-CHE-2015-SEQUENCE LISTING [04-11-2022(online)].txt | 2022-11-04 |
| 12 | 5931-CHE-2015-Correspondence-F1-PA-050116.pdf | 2016-06-16 |
| 12 | 5931-CHE-2015-FER_SER_REPLY [04-11-2022(online)].pdf | 2022-11-04 |
| 13 | 5931-CHE-2015-CLAIMS [04-11-2022(online)].pdf | 2022-11-04 |
| 13 | 5931-CHE-2015-Form 1-050116.pdf | 2016-06-16 |
| 14 | 5931-CHE-2015-Power of Attorney-050116.pdf | 2016-06-16 |
| 14 | 5931-CHE-2015-US(14)-HearingNotice-(HearingDate-05-10-2023).pdf | 2023-09-05 |
| 15 | 5931-CHE-2015-Correspondence to notify the Controller [03-10-2023(online)].pdf | 2023-10-03 |
| 15 | Description(Complete) [02-11-2015(online)].pdf | 2015-11-02 |
| 16 | 5931-CHE-2015-FORM-26 [04-10-2023(online)].pdf | 2023-10-04 |
| 16 | Drawing [02-11-2015(online)].pdf | 2015-11-02 |
| 17 | 5931-CHE-2015-Written submissions and relevant documents [19-10-2023(online)].pdf | 2023-10-19 |
| 17 | Form 3 [02-11-2015(online)].pdf | 2015-11-02 |
| 18 | 5931-CHE-2015-PatentCertificate20-10-2023.pdf | 2023-10-20 |
| 18 | Form 5 [02-11-2015(online)].pdf | 2015-11-02 |
| 19 | 5931-CHE-2015-IntimationOfGrant20-10-2023.pdf | 2023-10-20 |
| 1 | SearchE_28-04-2022.pdf |