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A Composition Comprising Chlorogenic Acid And At Least One Plant Extract For Inhibition Of Adipogenesis

Abstract: The present disclosure relates to a composition comprising Coleus forskohlii extract, chlorogenic acid, and Garcinia cambogia extract and formulations of the same, which are useful in inhibiting adipogenesis.

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Patent Information

Application #
Filing Date
21 October 2015
Publication Number
17/2017
Publication Type
INA
Invention Field
BIO-CHEMISTRY
Status
Email
lsmds@lakshmisri.com
Parent Application

Applicants

ITC LIMITED
ITC LIFE SCIENCES & TECHNOLOGY CENTRE #3, 1st Main, Peenya Industrial Area, Phase 1, Bangalore 560 058, India

Inventors

1. DEVAN, Sabarinathan
ITC LIFE SCIENCES & TECHNOLOGY CENTRE #3, 1st Main, Peenya Industrial Area, Phase 1, Bangalore 560 058, India
2. RADHAKRISHNAN, Yashwanth
ITC LIFE SCIENCES & TECHNOLOGY CENTRE #3, 1st Main, Peenya Industrial Area, Phase 1, Bangalore 560 058, India
3. KS, Nandakumar
ITC LIFE SCIENCES & TECHNOLOGY CENTRE #3, 1st Main, Peenya Industrial Area, Phase 1, Bangalore 560 058, India
4. CHANDRASEKHARAN, Lakshmanan Chittur
ITC LIFE SCIENCES & TECHNOLOGY CENTRE #3, 1st Main, Peenya Industrial Area, Phase 1, Bangalore 560 058, India

Specification

Claims:1. A composition for inhibiting adipogenesis, said composition comprising:
a. Coleus forskohlii extract;
b. chlorogenic acid; and
c. Garcinia cambogia extract;
wherein Coleus forskohlii extract to chlorogenic acid w/w ratio in said composition is in the range of 2:1-1:2, chlorogenic acid to Garcinia cambogia extract w/w ratio in said composition is in the range of 2:1-1:2, and Garcinia cambogia extract to Coleus forskohlii extract w/w ratio in said composition is in the range of 2:1-1:2.
2. The composition as claimed in claim 1, wherein said Coleus forskohlii extract has forskolin content = 20%, and said Garcinia cambogia extract has hydroxyl citric acid content = 50%.
3. A method of preparing a composition as claimed in any of the claims 1-2.
4. A formulation for inhibiting adipogenesis, said formulation comprising:
a. Coleus forskohlii extract;
b. chlorogenic acid;
c. Garcinia cambogia extract, and
d. at least one carrier, diluent, and excipient,
wherein, Coleus forskohlii extract to chlorogenic acid w/w ratio in said composition is in the range of 2:1-1:2, wherein chlorogenic acid to Garcinia cambogia extract w/w ratio in said composition is in the range of 2:1-1:2, wherein Garcinia cambogia extract to Coleus forskohlii extract w/w ratio in said composition is in the range of 2:1-1:2.
5. The formulation as claimed in claim 5, wherein said Coleus forskohlii extract has forskolin content = 20%, and said Garcinia cambogia extract has hydroxyl citric acid content = 50%.
6. A method of preparing a formulation as claimed in any of the claims 4-5.
7. A method for inhibiting adipogenesis, said method comprising the steps of:
a. obtaining a composition comprising:
i. Coleus forskohlii extract;
ii. chlorogenic acid; and
iii. Garcinia cambogia extract;
b. contacting said composition with site of adipogenesis,
wherein Coleus forskohlii extract to chlorogenic acid w/w ratio in said composition is in the range of 2:1-1:2, wherein chlorogenic acid to Garcinia cambogia extract w/w ratio in said composition is in the range of 2:1-1:2, wherein Garcinia cambogia extract to Coleus forskohlii extract w/w ratio in said composition is in the range of 2:1-1:2.
8. A method for inhibiting adipogenesis, said method comprising the steps of:
a. obtaining a formulation comprising:
i. Coleus forskohlii extract;
ii. chlorogenic acid;
iii. Garcinia cambogia extract; and
iv. at least one carrier, diluent and excipient.
b. contacting said formulation with site of adipogenesis,
wherein Coleus forskohlii extract to chlorogenic acid w/w ratio in said formulation is in the range of 2:1-1:2, wherein chlorogenic acid to Garcinia cambogia extract w/w ratio in said formulation is in the range of 2:1-1:2, wherein Garcinia cambogia extract to Coleus forskohlii extract w/w ratio in said formulation is in the range of 2:1-1:2.
9. The method as claimed in any of the claims 7-8, wherein said Coleus forskohlii extract has forskolin content = 20%, and said Garcinia cambogia extract has hydroxyl citric acid content = 50%.
, Description:As Attached

Documents

Orders

Section Controller Decision Date

Application Documents

# Name Date
1 5682-CHE-2015-NBA INTIMATION TO APPLICANT COMPLY WITH REQUIREMENT-30-11-2023.pdf 2023-11-30
1 Sequence listing [21-10-2015(online)].pdf 2015-10-21
2 Form 5 [21-10-2015(online)].pdf 2015-10-21
2 5682-CHE-2015-Written submissions and relevant documents [06-07-2023(online)].pdf 2023-07-06
3 Form 3 [21-10-2015(online)].pdf 2015-10-21
3 5682-CHE-2015-FORM-26 [23-06-2023(online)].pdf 2023-06-23
4 Drawing [21-10-2015(online)].pdf 2015-10-21
4 5682-CHE-2015-Correspondence to notify the Controller [19-06-2023(online)].pdf 2023-06-19
5 Description(Complete) [21-10-2015(online)].pdf 2015-10-21
5 5682-CHE-2015-US(14)-HearingNotice-(HearingDate-23-06-2023).pdf 2023-06-06
6 5682-CHE-2015-Power of Attorney-301115.pdf 2016-03-22
6 5682-CHE-2015-FER_SER_REPLY [07-03-2022(online)].pdf 2022-03-07
7 5682-CHE-2015-Form 1-301115.pdf 2016-03-22
7 5682-CHE-2015-FER.pdf 2021-10-17
8 5682-CHE-2015-FORM 18 [05-09-2019(online)].pdf 2019-09-05
8 5682-CHE-2015-Correspondence-301115.pdf 2016-03-22
9 5682-CHE-2015-FORM 18 [05-09-2019(online)].pdf 2019-09-05
9 5682-CHE-2015-Correspondence-301115.pdf 2016-03-22
10 5682-CHE-2015-FER.pdf 2021-10-17
10 5682-CHE-2015-Form 1-301115.pdf 2016-03-22
11 5682-CHE-2015-Power of Attorney-301115.pdf 2016-03-22
11 5682-CHE-2015-FER_SER_REPLY [07-03-2022(online)].pdf 2022-03-07
12 Description(Complete) [21-10-2015(online)].pdf 2015-10-21
12 5682-CHE-2015-US(14)-HearingNotice-(HearingDate-23-06-2023).pdf 2023-06-06
13 Drawing [21-10-2015(online)].pdf 2015-10-21
13 5682-CHE-2015-Correspondence to notify the Controller [19-06-2023(online)].pdf 2023-06-19
14 Form 3 [21-10-2015(online)].pdf 2015-10-21
14 5682-CHE-2015-FORM-26 [23-06-2023(online)].pdf 2023-06-23
15 Form 5 [21-10-2015(online)].pdf 2015-10-21
15 5682-CHE-2015-Written submissions and relevant documents [06-07-2023(online)].pdf 2023-07-06
16 Sequence listing [21-10-2015(online)].pdf 2015-10-21
16 5682-CHE-2015-NBA INTIMATION TO APPLICANT COMPLY WITH REQUIREMENT-30-11-2023.pdf 2023-11-30

Search Strategy

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1 TKDlsearchstrategyE_28-07-2021.pdf
2 SearchHistoryE_28-07-2021.pdf
2 TKDlsearchstrategyE_28-07-2021.pdf