Abstract: The present disclosure relates to combination of extracts derived from Garcinia species, which show alpha glucosidase activity inhibition. Also provided in the present disclosure are methods of preparing combinations of said extracts, and application of the same in inhibiting enzyme activity.
Claims:1. A composition comprising:
a. Garcinia cambogia extract; and
b. Garcinia mangostana extract,
wherein G. cambogia to G. mangostana w/w ratio in said composition is in the range of 5:1-80:1.
2. The composition as claimed in claim 1, wherein G. cambogia weight percentage in said composition is in the range of 0.15-0.6%, and G. mangostana weight percentage in said composition is in the range of 0.0075-0.03%.
3. The composition as claimed in claim 1, wherein G. cambogia to G. mangostana w/w ratio in said composition is 5:1.
4. The composition as claimed in claim 3, wherein G. cambogia weight percentage in said composition is 0.15%, and G. mangostana weight percentage in said composition is 0.03%.
5. The composition as claimed in claim 1, wherein G. cambogia to G. mangostana w/w ratio in said composition is 13.33:1.
6. The composition as claimed in claim 5, wherein G. cambogia weight percentage in said composition is 0.3%, and G. mangostana weight percentage in said composition is 0.0225%.
7. The composition as claimed in claim 1, wherein G. cambogia to G. mangostana w/w ratio in said composition is 20:1.
8. The composition as claimed in claim 7, wherein G. cambogia weight percentage in said composition is 0.375%, and G. mangostana weight percentage in said composition is 0.01875%.
9. The composition as claimed in claim 1, wherein G. cambogia to G. mangostana w/w ratio in said composition is 30:1.
10. The composition as claimed in claim 9, wherein G. cambogia weight percentage in said composition is 0.45%, and G. mangostana weight percentage in said composition is 0.015%.
11. The composition as claimed in claim 1, wherein G. cambogia to G. mangostana w/w ratio in said composition is 80:1.
12. The composition as claimed in claim 11, wherein G. cambogia weight percentage in said composition is 0.6%, and G. mangostana weight percentage in said composition is 0.0075%.
13. The composition as claimed in any of the claims 1-12, further comprising suitable carriers, diluents, and excipients.
14. A method of preparing a composition as claimed in any of the claims 1-13.
15. A method of inhibiting alpha glucosidase activity, said method comprising:
a. obtaining a composition as claimed in any of the claims 1-13; and
b. contacting said composition with alpha glucosidase,
wherein said method inhibits alpha glucosidase activity.
, Description:As Attached
| # | Name | Date |
|---|---|---|
| 1 | 201641010904-NBA INTIMATION TO APPLICANT COMPLY WITH REQUIREMENT-23-09-2024.pdf | 2024-09-23 |
| 1 | Form 5 [29-03-2016(online)].pdf | 2016-03-29 |
| 2 | 201641010904-Written submissions and relevant documents [23-02-2024(online)].pdf | 2024-02-23 |
| 2 | Form 3 [29-03-2016(online)].pdf | 2016-03-29 |
| 3 | Drawing [29-03-2016(online)].pdf | 2016-03-29 |
| 3 | 201641010904-FORM-26 [08-02-2024(online)].pdf | 2024-02-08 |
| 4 | Description(Complete) [29-03-2016(online)].pdf | 2016-03-29 |
| 4 | 201641010904-Correspondence to notify the Controller [02-02-2024(online)].pdf | 2024-02-02 |
| 5 | Other Patent Document [20-05-2016(online)].pdf | 2016-05-20 |
| 5 | 201641010904-US(14)-HearingNotice-(HearingDate-09-02-2024).pdf | 2024-01-10 |
| 6 | Form 26 [20-05-2016(online)].pdf | 2016-05-20 |
| 6 | 201641010904-FER_SER_REPLY [16-03-2023(online)].pdf | 2023-03-16 |
| 7 | 201641010904-Power of Attorney-230516.pdf | 2016-07-20 |
| 7 | 201641010904-FER.pdf | 2022-09-16 |
| 8 | 201641010904-FORM 18 [27-03-2020(online)].pdf | 2020-03-27 |
| 8 | 201641010904-Form 1-230516.pdf | 2016-07-20 |
| 9 | 201641010904-Correspondence-Form 1-230516.pdf | 2016-07-20 |
| 9 | 201641010904-Correspondence-PA-230516.pdf | 2016-07-20 |
| 10 | 201641010904-Correspondence-Form 1-230516.pdf | 2016-07-20 |
| 10 | 201641010904-Correspondence-PA-230516.pdf | 2016-07-20 |
| 11 | 201641010904-Form 1-230516.pdf | 2016-07-20 |
| 11 | 201641010904-FORM 18 [27-03-2020(online)].pdf | 2020-03-27 |
| 12 | 201641010904-FER.pdf | 2022-09-16 |
| 12 | 201641010904-Power of Attorney-230516.pdf | 2016-07-20 |
| 13 | 201641010904-FER_SER_REPLY [16-03-2023(online)].pdf | 2023-03-16 |
| 13 | Form 26 [20-05-2016(online)].pdf | 2016-05-20 |
| 14 | 201641010904-US(14)-HearingNotice-(HearingDate-09-02-2024).pdf | 2024-01-10 |
| 14 | Other Patent Document [20-05-2016(online)].pdf | 2016-05-20 |
| 15 | 201641010904-Correspondence to notify the Controller [02-02-2024(online)].pdf | 2024-02-02 |
| 15 | Description(Complete) [29-03-2016(online)].pdf | 2016-03-29 |
| 16 | 201641010904-FORM-26 [08-02-2024(online)].pdf | 2024-02-08 |
| 16 | Drawing [29-03-2016(online)].pdf | 2016-03-29 |
| 17 | 201641010904-Written submissions and relevant documents [23-02-2024(online)].pdf | 2024-02-23 |
| 17 | Form 3 [29-03-2016(online)].pdf | 2016-03-29 |
| 18 | Form 5 [29-03-2016(online)].pdf | 2016-03-29 |
| 18 | 201641010904-NBA INTIMATION TO APPLICANT COMPLY WITH REQUIREMENT-23-09-2024.pdf | 2024-09-23 |
| 1 | Search_HistoryE_14-09-2022.pdf |