Abstract: The present disclosure provides a composition comprising of mangiferin, and beta-D-glucan, which at particular w/w ratios exhibits synergistic increase in cellular uptake of extracellular glucose. Also provided in the present disclosure are methods of promoting cellular uptake of glucose.
CLIAMS:1. A composition for promoting cellular uptake of extracellular glucose, said composition comprising:
a. mangiferin; and
b. beta-D-glucan.
2. The composition as claimed in claim 1, wherein mangiferin to beta-D-glucan w/w ratio in said composition is 1.22:1-2.33:1.
3. The composition as claimed in claim 1, optionally comprising of suitable carriers, diluents, and excipients.
4. A method of promoting cellular uptake of extracellular glucose, said method comprising:
a. obtaining a composition as claimed in claim 1; and
b. contacting said composition with a cell capable of extracellular glucose uptake;
wherein said method promotes cellular uptake of extracellular glucose.
5. A method of preparing the composition as claimed in claim 1.
6. Use of a composition as claimed in claim 1 in promoting intracellular uptake of glucose.
7. A method of management of glucose homeostasis, said method comprising of:
a. obtaining a composition as claimed in claim 1; and
b. administering said composition to a person in need of managing glucose homeostasis.
,TagSPECI:As attached
| # | Name | Date |
|---|---|---|
| 1 | PD014942IN-SC SPEC FOR FILING.pdf | 2015-03-12 |
| 2 | PD014942IN-SC FORM 5.pdf | 2015-03-12 |
| 3 | PD014942IN-SC FORM 3.pdf | 2015-03-12 |
| 4 | PD014942IN-SC FIGURES FOR FILING.pdf | 2015-03-12 |
| 5 | 309-CHE-2015 POWER OF ATTORNEY 27-03-2015.pdf | 2015-03-27 |
| 6 | 309-CHE-2015 FORM-1 27-03-2015.pdf | 2015-03-27 |
| 7 | 309-CHE-2015 CORRESPONDENCE OTHERS 27-03-2015.pdf | 2015-03-27 |
| 8 | 309-CHE-2015-FORM 18 [04-12-2018(online)].pdf | 2018-12-04 |
| 9 | 309-CHE-2015-FER.pdf | 2021-10-17 |
| 10 | 309-CHE-2015-FER_SER_REPLY [17-03-2022(online)].pdf | 2022-03-17 |
| 11 | 309-CHE-2015-CLAIMS [17-03-2022(online)].pdf | 2022-03-17 |
| 12 | 309-CHE-2015-US(14)-HearingNotice-(HearingDate-14-03-2023).pdf | 2023-02-16 |
| 13 | 309-CHE-2015-Correspondence to notify the Controller [10-03-2023(online)].pdf | 2023-03-10 |
| 14 | 309-CHE-2015-FORM-26 [13-03-2023(online)].pdf | 2023-03-13 |
| 15 | 309-CHE-2015-Written submissions and relevant documents [28-03-2023(online)].pdf | 2023-03-28 |
| 16 | 309-CHE-2015-PatentCertificate23-05-2023.pdf | 2023-05-23 |
| 17 | 309-CHE-2015-IntimationOfGrant23-05-2023.pdf | 2023-05-23 |
| 1 | SearchStrategy309CHE2015E_27-02-2021.pdf |