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A Composition Comprising Of Anthocyanin And 7, 8, 4 Trihydroxy Isoflavone And Uses Thereof

Abstract: The present disclosure relates to a composition comprising of at least one natural plant extract and 7,8,4-trihydroxy isoflavone, wherein said composition synergistically enhances inhibition of alpha-glucosidase acitivity for maintenance of metabolic health. Also provided are formulations for the same, and methods of maintaining metabolic homeostasis.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
08 October 2013
Publication Number
39/2015
Publication Type
INA
Invention Field
TRADITIONAL KNOWLEDGE CHEMICAL
Status
Email
lsmds@lakshmisri.com
Parent Application
Patent Number
Legal Status
Grant Date
2021-01-20
Renewal Date

Applicants

ITC LIMITED
ITC Life Sciences & Technology Centre, #3, 1st Main, Peenya Industrial Area, Phase 1, Bangalore 560058

Inventors

1. FATIMA, Humaira
ITC Life Sciences and Technology Centre #3, 1st Main, Peenya Industrial Area, Phase 1, Bangalore, 560 058
2. DEVAN, Sabarinathan
ITC Life Sciences and Technology Center #3, 1st Main, Peenya Industrial Area, Phase 1, Bangalore, 560 058
3. DIXIT, Ajay Kumar
ITC Life Sciences and Technology Center #3, 1st Main, Peenya Industrial Area, Phase 1, Bangalore, 560 058
4. Nandakumar KS
ITC Life Sciences and Technology Centre #3, 1st Main, Peenya Industrial Area, Phase 1, Bangalore, 560 058
5. RADHAKRISHNAN, Yashwanth
ITC Life Sciences and Technology Centre #3, 1st Main, Peenya Industrial Area, Phase 1, Bangalore, 560 058
6. CHITTUR, Lakshmanan Chandrasekharan
ITC Life Sciences and Technology Centre #3, 1st Main, Peenya Industrial Area, Phase 1, Bangalore, 560 058

Specification

DESC:A COMPOSITION COMPRISING OF ANTHOCYANIN AND 7, 8, 4-TRIHYDROXY ISOFLAVONE AND USES THEREOF ,CLAIMS:1. A composition comprising of at least one natural extract and 7,8,4-trihydroxy isoflavone, wherein said composition inhibits alpha-glucosidase.
2. The composition as claimed in claim 1, wherein at least one natural extract is selected from the group consisting of celery extract, cocoa extract, black currant extract, cranberry extract, acai extract, black raspberry extract, red currant extract, pomegranate extract, mango extract, purple corn extract, chokeberry extract, eggplant extract, blueberry extract, and combinations thereof.
3. The composition as claimed in claim 2, wherein the natural extract has anthocyanin concentration of at least 25%, or ellagic acid concentration of at least 70%, or theobromine concentration of at least 7%, or oleuropein concentration of at least 20%.
4. The composition as claimed in claim 1, wherein the at least one natural extract to 7,8,4-trihydroxy isoflavone w/w ratio in said composition is in the range of 4:1-1:4, preferably 3:2-2:3.
5. The composition as claimed in claim 1, wherein the at least one natural extract concentration in said composition is in the range of 0.01%-0.1%, preferably 0.025%-0.075%.
6. The composition as claimed in claim 1, wherein the 7,8,4-trihydroxy isoflavone concentration in said composition is in the range of 0.01%-0.1%, preferably 0.025%-0.075%.
7. A method of inhibiting alpha-glucosidase by contacting a composition as claimed in claim 1 with alpha-glucosidase.
8. A formulation for oral ingestion comprising a composition as claimed in claim 1.
9. The formulation as claimed in claim 8, wherein the at least one natural extract to 7,8,4-trihydroxy isoflavone w/w ratio in said formulation is in the range of 4:1-1:4, preferably 3:2-2:3.
10. The formulation as claimed in claim 8, wherein the at least one natural extract concentration in said composition is in the range of 0.01%-0.1%, preferably 0.025%-0.075%.

Documents

Application Documents

# Name Date
1 4564-CHE-2013-RELEVANT DOCUMENTS [29-09-2022(online)].pdf 2022-09-29
1 SPECIFICATION.pdf 2013-10-18
2 FORM 3.pdf 2013-10-18
2 4564-CHE-2013-IntimationOfGrant20-01-2021.pdf 2021-01-20
3 FIGURES.pdf 2013-10-18
3 4564-CHE-2013-PatentCertificate20-01-2021.pdf 2021-01-20
4 4564-CHE-2013-CLAIMS [03-07-2019(online)].pdf 2019-07-03
4 4564-CHE-2013 POWER OF ATTORNEY 25-11-2013.pdf 2013-11-25
5 4564-CHE-2013-FER_SER_REPLY [03-07-2019(online)].pdf 2019-07-03
5 4564-CHE-2013 FORM-1 25-11-2013.pdf 2013-11-25
6 4564-CHE-2013-FER.pdf 2019-01-04
6 4564-CHE-2013 CORRESPONDENCE OTHERS 25-11-2013.pdf 2013-11-25
7 SPEC FOR E-FILING.pdf 2014-07-23
7 Form 18 [20-01-2017(online)].pdf 2017-01-20
8 FIG IN.pdf 2014-07-23
9 SPEC FOR E-FILING.pdf 2014-07-23
9 Form 18 [20-01-2017(online)].pdf 2017-01-20
10 4564-CHE-2013 CORRESPONDENCE OTHERS 25-11-2013.pdf 2013-11-25
10 4564-CHE-2013-FER.pdf 2019-01-04
11 4564-CHE-2013-FER_SER_REPLY [03-07-2019(online)].pdf 2019-07-03
11 4564-CHE-2013 FORM-1 25-11-2013.pdf 2013-11-25
12 4564-CHE-2013-CLAIMS [03-07-2019(online)].pdf 2019-07-03
12 4564-CHE-2013 POWER OF ATTORNEY 25-11-2013.pdf 2013-11-25
13 FIGURES.pdf 2013-10-18
13 4564-CHE-2013-PatentCertificate20-01-2021.pdf 2021-01-20
14 FORM 3.pdf 2013-10-18
14 4564-CHE-2013-IntimationOfGrant20-01-2021.pdf 2021-01-20
15 SPECIFICATION.pdf 2013-10-18
15 4564-CHE-2013-RELEVANT DOCUMENTS [29-09-2022(online)].pdf 2022-09-29

Search Strategy

1 2019-01-0110-35-48-converted_01-01-2019.pdf

ERegister / Renewals

3rd: 05 Mar 2021

From 08/10/2015 - To 08/10/2016

4th: 05 Mar 2021

From 08/10/2016 - To 08/10/2017

5th: 05 Mar 2021

From 08/10/2017 - To 08/10/2018

6th: 05 Mar 2021

From 08/10/2018 - To 08/10/2019

7th: 05 Mar 2021

From 08/10/2019 - To 08/10/2020

8th: 05 Mar 2021

From 08/10/2020 - To 08/10/2021