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A Composition Comprising Phytic Acid, And (R) ( ) 2 Oxothiazolidine 4 Carboxylic Acid For Inhibiting Glycation And Uses Thereof

Abstract: The present disclosure composition comprising phytic acid and (R)-(-)-2-oxothiazolidine-4-carboxylic acid for inhibition of glycation.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
19 August 2015
Publication Number
08/2017
Publication Type
INA
Invention Field
TRADITIONAL KNOWLEDGE BIOTECHNOLOGY
Status
Email
lsmds@lakshmisri.com
Parent Application

Applicants

ITC LIMITED
ITC Life Sciences and Technology Centre, #3, 1st Main, Peenya Industrial Area, Phase 1, Bangalore 560 058, India

Inventors

1. AGARWAL, Sakshi
ITC Life Sciences and Technology Centre #3. 1st Main, Peenya Industrial Area, Phase-1, Bangalore 560 058, India
2. KHAN, Manisha
ITC Life Sciences and Technology Centre #3. 1st Main, Peenya Industrial Area, Phase-1, Bangalore 560 058, India
3. HASSAN, Sarah
ITC Life Sciences and Technology Centre #3. 1st Main, Peenya Industrial Area, Phase-1, Bangalore 560 058, India
4. PHULERA, Sumit
ITC Life Sciences and Technology Centre #3. 1st Main, Peenya Industrial Area, Phase-1, Bangalore 560 058, India

Specification

Claims:1. An anti-glycation composition comprising:
a. phytic acid; and
b. (R)-(-)-2-oxothiazolidine-4-carboxylic acid,
wherein phytic acid weight concentration is in the range of 0.00009-0.00012%, and (R)-(-)-2-oxothiazolidine-4-carboxylic acid weight concentration is in the range of 0.009-0.012%.
2. An anti-glycation formulation comprising:
a. phytic acid; and
b. (R)-(-)-2-oxothiazolidine-4-carboxylic acid,
wherein phytic acid weight concentration is in the range of 0.00009-0.00012%, and (R)-(-)-2-oxothiazolidine-4-carboxylic acid weight concentration is in the range of 0.009-0.012%.
3. The anti-glycation formulation as claimed in claim 2, further comprising at least one cosmetically acceptable ingredient.
4. The anti-glycation formulation as claimed in claim 3, wherein the cosmetically acceptable ingredient is selected from the group consisting of suitable carriers, diluents, skin benefitting agents, pH adjusting agents, emollients, moisturizing agents, antimicrobial agents, and excipients.
5. A method of preparing an anti-glycation composition comprising phytic acid; and (R)-(-)-2-oxothiazolidine-4-carboxylic acid, wherein phytic acid weight concentration is in the range of 0.00009-0.00012%, and (R)-(-)-2-oxothiazolidine-4-carboxylic acid weight concentration is in the range of 0.009-0.012%.
6. A method of preparing an anti-glycation formulation comprising phytic acid; (R)-(-)-2-oxothiazolidine-4-carboxylic acid, and suitable carriers, diluents, and excipients, wherein wherein phytic acid weight concentration is in the range of 0.00009-0.00012%, and (R)-(-)-2-oxothiazolidine-4-carboxylic acid weight concentration is in the range of 0.009-0.012%.
7. An anti-glycation formulation for topical application comprising:
a. phytic acid having weight concentration of 0.0001%;
b. (R)-(-)-2-oxothiazolidine-4-carboxylic acid having weight concentration of 0.01%;
c. acrylates/C10-30 alkyl acrylate cross-polymer having volume percentage of 0.07%;
d. glycerin having volume percentage of 5%;
e. butylene glycol having volume percentage of 2%;
f. D-Panthenol having volume percentage of 0.5%;
g. triethanolamine having volume percentage of 0.06%;
h. mineral oil having volume percentage of 4%;
i. cetyl alcohol having volume percentage of 3%;
j. glycol distearate having volume percentage of 3%;
k. dimethicone having volume percentage of 0.5%;
l. allantoin having volume percentage of 0.1%;
m. phenoxyethanol having volume percentage of 0.3%;
n. fragrance having volume percentage of 0.2%; and
o. water having volume percentage of 81.26%.
8. A method of preparing an anti-glycation formulation for topical application comprising: a) phytic acid having weight concentration of 0.0001%; b) (R)-(-)-2-oxothiazolidine-4-carboxylic acid having weight concentration of 0.01%; c) acrylates/C10-30 alkyl acrylate cross-polymer having volume percentage of 0.07%; d) glycerin having volume percentage of 5%; e) butylene glycol having volume percentage of 2%; f) D-Panthenol having volume percentage of 0.5%; g) triethanolamine having volume percentage of 0.06%; h) mineral oil having volume percentage of 4%; i) cetyl alcohol having volume percentage of 3%; j) glycol distearate having volume percentage of 3%; k) dimethicone having volume percentage of 0.5%; l) allantoin having volume percentage of 0.1%; m) phenoxyethanol having volume percentage of 0.3%; n) fragrance having volume percentage of 0.2%; and o) water having volume percentage of 81.26%.
9. A method for inhibiting glycation, said method comprising the steps:
a. obtaining a composition or a formulation comprising phytic acid; and (R)-(-)-2-oxothiazolidine-4-carboxylic acid, wherein phytic acid weight concentration is in the range of 0.00009-0.00012%, and (R)-(-)-2-oxothiazolidine-4-carboxylic acid weight concentration is in the range of 0.009-0.012%; and
b. contacting said composition or formulation with a site susceptible to glycation,
wherein said method inhibits glycation.
, Description:As Attached

Documents

Application Documents

# Name Date
1 4347-CHE-2015-FER.pdf 2021-10-17
1 Form 5 [19-08-2015(online)].pdf 2015-08-19
2 4347-CHE-2015-FORM 18 [09-07-2019(online)].pdf 2019-07-09
2 Form 3 [19-08-2015(online)].pdf 2015-08-19
3 Description(Complete) [19-08-2015(online)].pdf 2015-08-19
3 4347-CHE-2015-Correspondence-FORM-1-P.A-041115.pdf 2016-04-07
4 Other Document [04-09-2015(online)].pdf 2015-09-04
4 4347-CHE-2015-Form 1-041115.pdf 2016-04-07
5 4347-CHE-2015-Power of Attorney-041115.pdf 2016-04-07
5 Form 13 [04-09-2015(online)].pdf 2015-09-04
6 4347-CHE-2015 FORM-13 04-09-2015.pdf 2015-09-04
7 4347-CHE-2015-Power of Attorney-041115.pdf 2016-04-07
7 Form 13 [04-09-2015(online)].pdf 2015-09-04
8 4347-CHE-2015-Form 1-041115.pdf 2016-04-07
8 Other Document [04-09-2015(online)].pdf 2015-09-04
9 4347-CHE-2015-Correspondence-FORM-1-P.A-041115.pdf 2016-04-07
9 Description(Complete) [19-08-2015(online)].pdf 2015-08-19
10 Form 3 [19-08-2015(online)].pdf 2015-08-19
10 4347-CHE-2015-FORM 18 [09-07-2019(online)].pdf 2019-07-09
11 Form 5 [19-08-2015(online)].pdf 2015-08-19
11 4347-CHE-2015-FER.pdf 2021-10-17

Search Strategy

1 SearchStrategy4347E_04-11-2020.pdf