Abstract: The present disclosure provides a composition comprising at least one small molecule, and L-arginine, which at particular w/w ratios exhibits enhanced collagen levels, which is an indicator of younger looking skin with reduced wrinkles and fine lines.
Claims:1. A composition comprising:
a. at least one molecule selected from the group consisting of:
i. N-[(4-ethylphenyl)methyl]-1-propanoyl-2,3-dihydro-1H-indole-2-carboxamide; and
ii. N-({1-[(2-fluorophenyl)methyl]piperidin-4-yl}methyl)-1-propanoyl-2,3-dihydroindole-2-carboxamide; and
b. L-arginine,
wherein at least one molecule to L-arginine w/w ratio in said composition is in the range of 1:42.5-1:690.
2. The composition as claimed in claim 1, wherein at least one molecule weight percentage in said composition is in the range of 0.0001-0.0004%, and L-arginine weight percentage in said composition is in the range of 0.017-0.069%.
3. The composition as claimed in claim 1, wherein at least one molecule to L-arginine w/w ratio in said composition is in the range of 1:85-1:340.
4. The composition as claimed in claim 3, wherein at least one molecule weight percentage in said composition is in the range of 0.0001-0.0004%, and L-arginine weight percentage in said composition is 0.034%.
5. The composition as claimed in claim 1, wherein at least one molecule to L-arginine w/w ratio in said composition is 1:85
6. The composition as claimed in claim 5, wherein at least one molecule weight percentage in said composition is 0.0004%, and L-arginine weight percentage in said composition is 0.034%.
7. The composition as claimed in claim 1, wherein at least one molecule to L-arginine w/w ratio in said composition is 1:170.
8. The composition as claimed in claim 7, wherein at least one molecule weight percentage in said composition is 0.0002%, and L-arginine weight percentage in said composition is 0.034%.
9. The composition as claimed in claim 1, wherein at least one molecule to L-arginine w/w ratio in said composition is 1:340.
10. The composition as claimed in claim 9, wherein at least one molecule weight percentage in said composition is 0.0001%, and L-arginine weight percentage in said composition is 0.034%.
11. The composition as claimed in any of the claims 3-10, wherein said at least one molecule is N-[(4-ethylphenyl)methyl]-1-propanoyl-2,3-dihydro-1H-indole-2-carboxamide.
12. The composition as claimed in any of the claims 3-10, wherein said at least one molecule is N-({1-[(2-fluorophenyl)methyl]piperidin-4-yl}methyl)-1-propanoyl-2,3-dihydroindole-2-carboxamide.
13. The composition as claimed in any of the claims 1-12, further comprising:
a. carriers;
b. diluents; and
c. excipients.
14. A method of preparing a composition as claimed in any of the claims 1-13.
15. A method of inhibiting appearance of skin aging, said method comprising:
a. obtaining a composition as claimed in any of the claims 1-13; and
b. contacting said composition with skin,
wherein said method inhibits appearance of skin aging.
, Description:As Attached
| # | Name | Date |
|---|---|---|
| 1 | Form 5 [11-04-2016(online)].pdf | 2016-04-11 |
| 2 | Form 3 [11-04-2016(online)].pdf | 2016-04-11 |
| 3 | Drawing [11-04-2016(online)].pdf | 2016-04-11 |
| 4 | Description(Complete) [11-04-2016(online)].pdf | 2016-04-11 |
| 5 | Other Patent Document [26-05-2016(online)].pdf | 2016-05-26 |
| 6 | Form 26 [26-05-2016(online)].pdf | 2016-05-26 |
| 7 | 201641012730-Power of Attorney-020616.pdf | 2016-07-21 |
| 8 | 201641012730-Form 1-020616.pdf | 2016-07-21 |
| 9 | 201641012730-Correspondence-F1-PA-020616.pdf | 2016-07-21 |
| 10 | 201641012730-CORRESPONDENCE-02022016.pdf | 2016-07-21 |
| 11 | 201641012730-FORM 18 [09-04-2020(online)].pdf | 2020-04-09 |
| 12 | 201641012730-FER.pdf | 2021-10-17 |
| 1 | Searchstratogy-GooglePatentsE_10-08-2020.pdf |