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A Composition For Inhibition Of Hair Growth

Abstract: The present disclosure relates to a composition comprising glycyrrhizic acid and Gymnema sylvestre extract which at specific w/w ratios is able to inhibit the expression levels of ornithine decarboxylase and insulin-like growth factor-1 genes thus, aid in the inhibition or delay of hair growth. Also provided are the methods of preparation and usage of the same.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
31 March 2017
Publication Number
40/2018
Publication Type
INA
Invention Field
BIOTECHNOLOGY
Status
Email
iprdel@lakshmisri.com
Parent Application

Applicants

ITC LIMITED
ITC LIFE SCIENCES & TECHNOLOGY CENTRE #3, 1st Main, Peenya Industrial Area, Phase - 1, Bangalore 560 058, India

Inventors

1. KAREMPUDI, Pavani
ITC Life Sciences & Technology Centre, Peenya Industrial Area, No. 3, 1st Main, 1st Phase Bangalore Karnataka 560 058, India
2. HEGDE, Ashok
ITC Life Sciences & Technology Centre #3, 1st Main, Peenya Industrial Area, Phase 1,Bangalore 560 058, India
3. KALSI, Gurpreet
ITC Life Sciences & Technology Centre #3, 1st Main, Peenya Industrial Area, Phase-1,Bangalore 560 058, India

Specification

DESC:A COMPOSITION FOR INHIBITION OF HAIR GROWTH ,CLAIMS:1. A composition comprising:
(a) glycyrrhizic acid; and
(b) Gymnema sylvestre extract,
wherein glycyrrhizic acid to the Gymnema sylvestre extract w/w ratio in said composition is in the range of 1:0.25 - 1:4.
2. The composition as claimed in claim 1, wherein glycyrrhizic acid to the Gymnema sylvestre extract w/w ratio in said composition is in the range of 1:1.5 – 1:4.
3. The composition as claimed in claim 1, wherein glycyrrhizic acid to the Gymnema sylvestre extract w/w ratio in said composition is 1:1.5.
4. The composition as claimed in claim 1, wherein the Gymnema sylvestre extract contains gymnemic acid in the range of 75 – 85 %.
5. The composition as claimed in claim 1, further comprising:
(a) at least one carrier;
(b) at least one diluent; and
(c) at least one excipient.
6. A process for preparing a composition as claimed in claim 1, comprising:
(a) obtaining glycyrrhizic acid;
(b) obtaining Gymnema sylvestre extract; and
(c) contacting glycyrrhizic acid and the Gymnema sylvestre extract to obtain said composition.
7. A process for preparing a composition, as claimed in any of the claims 1-5, comprising:
(a) obtaining glycyrrhizic acid;
(b) obtaining Gymnema sylvestre extract;
(c) obtaining at least one carrier;
(d) obtaining at least one diluent;
(e) obtaining at least one excipient; and
(f) contacting glycyrrhizic acid, the Gymnema sylvestre extract, the at least one carrier, the at least one diluent, and the at least one excipient, to obtain said composition.
8. A method to inhibit hair growth, comprising:
(a) obtaining the composition as claimed in any of the claims 1-5; and
(b) contacting said composition with hair follicles,
wherein said composition inhibits hair growth.
9. The composition as claimed in any of the claims 1-5, wherein said composition inhibits hair growth by inhibiting the enzyme ornithine decarboxylase.
10. The composition as claimed in any of the claims 1-5, wherein said composition inhibits hair growth by inhibiting the insulin-like growth factor 1.

Documents

Application Documents

# Name Date
1 Form 3 [31-03-2017(online)].pdf 2017-03-31
2 Drawing [31-03-2017(online)].pdf 2017-03-31
3 Description(Provisional) [31-03-2017(online)].pdf 2017-03-31
4 Form 26 [12-05-2017(online)].pdf 2017-05-12
5 Correspondence by Agent_Form 26_18-05-2017.pdf 2017-05-18
6 Other Patent Document [22-05-2017(online)].pdf 2017-05-22
7 Correspondence by Agent_Form1_26-05-2017.pdf 2017-05-26
8 201741011853-DRAWING [03-11-2017(online)].pdf 2017-11-03
9 201741011853-CORRESPONDENCE-OTHERS [03-11-2017(online)].pdf 2017-11-03
10 201741011853-COMPLETE SPECIFICATION [03-11-2017(online)].pdf 2017-11-03