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A Composition For Promoting Hair Growth

Abstract: The present disclosure relates to a composition comprising retinoic acid and wedelolactone which at specific w/w ratios enhances the expression levels of NOG, VEGF, and IGF-1 genes, thus promoting growth of hair. Also provided are the methods for preparation and uses thereof.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
27 September 2017
Publication Number
13/2019
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
iprdel@lakshmisri.com
Parent Application
Patent Number
Legal Status
Grant Date
2022-05-10
Renewal Date

Applicants

ITC LIMITED
ITC LIFE SCIENCES & TECHNOLOGY CENTRE #3. 1st Main, Peenya Industrial Area, Phase-1, Bangalore 560 058, India

Inventors

1. HEGDE, Ashok
ITC Life Sciences & Technology Centre, Peenya Industrial Area, No.3, 1st Main, 1st Phase Bangalore-560058, Karnataka, India
2. KAREMPUDI, Pavani
ITC Life Sciences & Technology Centre, Peenya Industrial Area, No.3, 1st Main, 1st Phase Bangalore-560058, Karnataka, India
3. KALSI, Gurpreet
ITC Life Sciences & Technology Centre, Peenya Industrial Area, No.3, 1st Main, 1st Phase Bangalore-560058, Karnataka, India
4. CHANDRASEKHARAN,Lakshmanan Chittur
ITC Life Sciences & Technology Centre, Peenya Industrial Area, No.3, 1st Main, 1st Phase Bangalore-560058, Karnataka, India

Specification

Claims:1. A composition for promoting hair growth, said composition comprising:
a) retinoic acid and salts thereof; and
b) wedelolactone,
wherein retinoic acid and salts thereof to wedelolactone w/w ratio in said composition is in the range of 1:1.25 - 1:10.
2. The composition as claimed in claim 1, wherein retinoic acid and salts thereof to wedelolactone w/w ratio in said composition is in the range of 1:1.25 – 1:3.5.

3. The composition as claimed in claim 1, wherein retinoic acid and salts thereof to wedelolactone w/w ratio in said composition is 1:1.5.

4. The composition as claimed in any of the claims 1-3, further comprising at least one carrier, at least one diluent, at least one excipient, and combinations thereof.

5. A method for preparing a composition as claimed in claim 1, said method comprising:
a) obtaining retinoic acid and salts thereof;
b) obtaining wedelolactone; and
c) contacting retinoic acid and salts thereof, and wedelolactone to obtain said composition.

6. A method for preparing a composition as claimed in any of the claims 1-4, said method comprising:
a) obtaining retinoic acid and salts thereof;
b) obtaining wedelolactone;
c) obtaining at least one carrier;
d) obtaining at least one diluent;
e) obtaining at least one excipient; and
f) contacting retinoic acid and salts thereof, wedelolactone, the at least one carrier, the at least one diluent, and the at least one excipient to obtain said composition.

7. The composition as claimed in any of the claims 1-4, wherein said composition increases hair growth by increasing the expression of Vascular Endothelial Growth Factor (VEGF) gene.

8. The composition as claimed in any of the claims 1-4, wherein said composition increases hair growth by increasing the expression of Noggin (NOG) gene.

9. The composition as claimed in any of the claims 1-4, wherein said composition increases hair growth by increasing the expression of Insulin-like Growth Factor 1 (IGF-1) gene.

10. A method for promoting hair growth, said method comprising:

a) obtaining a composition as claimed in any of the claims 1-4; and
b) contacting said composition with hair follicles,
wherein said composition promotes hair growth.
, Description:AS ATTACHED

Documents

Application Documents

# Name Date
1 201741034387-STATEMENT OF UNDERTAKING (FORM 3) [27-09-2017(online)].pdf 2017-09-27
2 201741034387-SEQUENCE LISTING(PDF) [27-09-2017(online)].pdf 2017-09-27
4 201741034387-DRAWINGS [27-09-2017(online)].pdf 2017-09-27
5 201741034387-DECLARATION OF INVENTORSHIP (FORM 5) [27-09-2017(online)].pdf 2017-09-27
6 201741034387-COMPLETE SPECIFICATION [27-09-2017(online)].pdf 2017-09-27
7 201741034387-Proof of Right (MANDATORY) [25-10-2017(online)].pdf 2017-10-25
8 201741034387-FORM-26 [25-10-2017(online)].pdf 2017-10-25
9 Correspondence by Agent_Form 1_Power of Attorney_30-10-2017.pdf 2017-10-30
10 201741034387-FORM 18 [16-08-2021(online)].pdf 2021-08-16
11 201741034387-FER.pdf 2021-10-17
12 201741034387-OTHERS [25-02-2022(online)].pdf 2022-02-25
13 201741034387-FORM 3 [25-02-2022(online)].pdf 2022-02-25
14 201741034387-FER_SER_REPLY [25-02-2022(online)].pdf 2022-02-25
15 201741034387-US(14)-HearingNotice-(HearingDate-19-04-2022).pdf 2022-03-18
16 201741034387-Correspondence to notify the Controller [11-04-2022(online)].pdf 2022-04-11
17 201741034387-Written submissions and relevant documents [03-05-2022(online)].pdf 2022-05-03
18 201741034387-PatentCertificate10-05-2022.pdf 2022-05-10
19 201741034387-IntimationOfGrant10-05-2022.pdf 2022-05-10

Search Strategy

1 tpoE_31-08-2021.pdf
2 search201741034387E_31-08-2021.pdf

ERegister / Renewals

3rd: 07 Jul 2022

From 27/09/2019 - To 27/09/2020

4th: 07 Jul 2022

From 27/09/2020 - To 27/09/2021

5th: 07 Jul 2022

From 27/09/2021 - To 27/09/2022

6th: 07 Jul 2022

From 27/09/2022 - To 27/09/2023

7th: 15 Sep 2023

From 27/09/2023 - To 27/09/2024

8th: 01 Aug 2024

From 27/09/2024 - To 27/09/2025

9th: 19 Sep 2025

From 27/09/2025 - To 27/09/2026