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A Composition For Promoting Skin Detoxification And Reducing Skin Aging Associated Symptoms, And Implementations Thereof

Abstract: The present disclosure discloses a composition comprising: trehalose and dihydro-oxyresveratrol, wherein trehalose to dihydro-oxyresveratrol weight ratio is in a range of 9500:1 to 10500:1. The composition exhibits anti-ageing, skin-whitening, and anti-oxidant effects on the skin. A formulation comprising the composition of the present disclosure has also been provided. The process of preparing the composition is also disclosed herein.

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Patent Information

Application #
Filing Date
29 March 2018
Publication Number
40/2019
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
iprdel@lakshmisri.com
Parent Application
Patent Number
Legal Status
Grant Date
2023-11-20
Renewal Date

Applicants

ITC LIMITED
ITC Life Sciences & Technology Centre 3, 1st main Road, Peenya Industrial Area, Phase 1, Bengaluru, Karnataka 560058, India

Inventors

1. MUTHAIYAH, Balu
ITC Life Sciences & Technology Centre 3, 1st main Road, Peenya Industrial Area, Phase 1, Bengaluru, Karnataka 560058, India
2. SRINIVASAN, Yuvaraj
ITC Life Sciences & Technology Centre 3, 1st main Road, Peenya Industrial Area, Phase 1, Bengaluru, Karnataka 560058, India
3. RAMADOSS, Sureshkumar
ITC Life Sciences & Technology Centre 3, 1st main Road, Peenya Industrial Area, Phase 1, Bengaluru, Karnataka 560058, India
4. KALLUKALAM, Bobby Cherian
ITC Life Sciences & Technology Centre 3, 1st main Road, Peenya Industrial Area, Phase 1, Bengaluru, Karnataka 560058, India
5. KALSI, Gurpreet
ITC Life Sciences & Technology Centre 3, 1st main Road, Peenya Industrial Area, Phase 1, Bengaluru, Karnataka 560058, India
6. BANDYOPADHYAY, Balaji
ITC Life Sciences & Technology Centre 3, 1st main Road, Peenya Industrial Area, Phase 1, Bengaluru, Karnataka 560058, India
7. CHANDRASEKHARAN, Lakshmanan Chittur
ITC Life Sciences & Technology Centre 3, 1st main Road, Peenya Industrial Area, Phase 1, Bengaluru, Karnataka 560058, India

Specification

I/We Claim:
1. A composition comprising:
a) trehalose; and
b) dihydro-oxyresveratrol,
wherein trehalose to dihydro-oxyresveratrol weight ratio is in a range of 9500:1 to 10500:1.
2. The composition as claimed in claim 1, wherein trehalose to dihydro-oxyresveratrol weight ratio is 10000:1.
3. The composition as claimed in any one of the claims 1 or 2, wherein the composition further comprises at least one excipient selected from the group consisting of water, polymer, gum base, chelating agent, emulsifier, surfactant, humectant, solvent, antimicrobial agent, moisturizer, fragrance, bulking agent, water, and combinations thereof.
4. The composition as claimed in any one of the claims 1-3, wherein the composition comprises trehalose having a concentration in a range of 75-125mM, and dihydro-oxyresveratrol having a concentration in a range of 7.5uMto 15 uM.
5. The composition as claimed in claim 4, wherein the composition comprises trehalose having a concentration of lOOmM, and dihydro-oxyresveratrol having a concentration of 10 uM.
6. The composition as claimed in claim 1, wherein the composition comprises: (a) trehalose having a weight percentage in a range of 2.5-4.5% with respect to the composition; and (b) dihydro-oxyresveratrol having a weight percentage in a range of 0.0002-0.0003% with respect to the composition.
7. A process for preparing the composition as claimed in claim 1, said process comprising:

a) obtaining trehalose;
b) obtaining dihydro-oxyresveratrol; and

c) contacting trehalose, and dihydro-oxyresveratrol to obtain the composition.
8. A process for preparing the composition as claimed in any one of the claims
1-7, said process comprising:
a) obtaining trehalose;
b) obtaining dihydro-oxyresveratrol;
c) obtaining the at least one excipient; and
d) contacting trehalose, dihydro-oxyresveratrol, and the at least one excipient, to obtain the composition.

9. The composition as claimed in any one of the claims 1-6, wherein the composition modulates autophagy process to exhibit anti-ageing effects.
10. The composition as claimed in any one of the claims 1-6, wherein the composition exhibits skin-whitening effects.

Documents

Application Documents

# Name Date
1 201841012018-STATEMENT OF UNDERTAKING (FORM 3) [29-03-2018(online)].pdf 2018-03-29
2 201841012018-FORM 1 [29-03-2018(online)].pdf 2018-03-29
3 201841012018-DRAWINGS [29-03-2018(online)].pdf 2018-03-29
4 201841012018-DECLARATION OF INVENTORSHIP (FORM 5) [29-03-2018(online)].pdf 2018-03-29
5 201841012018-COMPLETE SPECIFICATION [29-03-2018(online)].pdf 2018-03-29
6 201841012018-Proof of Right (MANDATORY) [03-05-2018(online)].pdf 2018-05-03
7 201841012018-FORM-26 [03-05-2018(online)].pdf 2018-05-03
8 Correspondence by Agent_Form26,Proof of Right_07-05-2018.pdf 2018-05-07
9 201841012018-FORM 18 [17-12-2021(online)].pdf 2021-12-17
10 201841012018-FER.pdf 2022-01-27
11 201841012018-FER_SER_REPLY [26-07-2022(online)].pdf 2022-07-26
12 201841012018-PatentCertificate20-11-2023.pdf 2023-11-20
13 201841012018-IntimationOfGrant20-11-2023.pdf 2023-11-20

Search Strategy

1 Search201841012018E_25-01-2022.pdf

ERegister / Renewals

3rd: 10 Jan 2024

From 29/03/2020 - To 29/03/2021

4th: 10 Jan 2024

From 29/03/2021 - To 29/03/2022

5th: 10 Jan 2024

From 29/03/2022 - To 29/03/2023

6th: 10 Jan 2024

From 29/03/2023 - To 29/03/2024

7th: 10 Jan 2024

From 29/03/2024 - To 29/03/2025

8th: 03 Mar 2025

From 29/03/2025 - To 29/03/2026