Abstract: The present disclosure discloses a composition comprising: trehalose and dihydro-oxyresveratrol, wherein trehalose to dihydro-oxyresveratrol weight ratio is in a range of 9500:1 to 10500:1. The composition exhibits anti-ageing, skin-whitening, and anti-oxidant effects on the skin. A formulation comprising the composition of the present disclosure has also been provided. The process of preparing the composition is also disclosed herein.
I/We Claim:
1. A composition comprising:
a) trehalose; and
b) dihydro-oxyresveratrol,
wherein trehalose to dihydro-oxyresveratrol weight ratio is in a range of 9500:1 to 10500:1.
2. The composition as claimed in claim 1, wherein trehalose to dihydro-oxyresveratrol weight ratio is 10000:1.
3. The composition as claimed in any one of the claims 1 or 2, wherein the composition further comprises at least one excipient selected from the group consisting of water, polymer, gum base, chelating agent, emulsifier, surfactant, humectant, solvent, antimicrobial agent, moisturizer, fragrance, bulking agent, water, and combinations thereof.
4. The composition as claimed in any one of the claims 1-3, wherein the composition comprises trehalose having a concentration in a range of 75-125mM, and dihydro-oxyresveratrol having a concentration in a range of 7.5uMto 15 uM.
5. The composition as claimed in claim 4, wherein the composition comprises trehalose having a concentration of lOOmM, and dihydro-oxyresveratrol having a concentration of 10 uM.
6. The composition as claimed in claim 1, wherein the composition comprises: (a) trehalose having a weight percentage in a range of 2.5-4.5% with respect to the composition; and (b) dihydro-oxyresveratrol having a weight percentage in a range of 0.0002-0.0003% with respect to the composition.
7. A process for preparing the composition as claimed in claim 1, said process comprising:
a) obtaining trehalose;
b) obtaining dihydro-oxyresveratrol; and
c) contacting trehalose, and dihydro-oxyresveratrol to obtain the composition.
8. A process for preparing the composition as claimed in any one of the claims
1-7, said process comprising:
a) obtaining trehalose;
b) obtaining dihydro-oxyresveratrol;
c) obtaining the at least one excipient; and
d) contacting trehalose, dihydro-oxyresveratrol, and the at least one excipient, to obtain the composition.
9. The composition as claimed in any one of the claims 1-6, wherein the composition modulates autophagy process to exhibit anti-ageing effects.
10. The composition as claimed in any one of the claims 1-6, wherein the composition exhibits skin-whitening effects.
| # | Name | Date |
|---|---|---|
| 1 | 201841012018-STATEMENT OF UNDERTAKING (FORM 3) [29-03-2018(online)].pdf | 2018-03-29 |
| 2 | 201841012018-FORM 1 [29-03-2018(online)].pdf | 2018-03-29 |
| 3 | 201841012018-DRAWINGS [29-03-2018(online)].pdf | 2018-03-29 |
| 4 | 201841012018-DECLARATION OF INVENTORSHIP (FORM 5) [29-03-2018(online)].pdf | 2018-03-29 |
| 5 | 201841012018-COMPLETE SPECIFICATION [29-03-2018(online)].pdf | 2018-03-29 |
| 6 | 201841012018-Proof of Right (MANDATORY) [03-05-2018(online)].pdf | 2018-05-03 |
| 7 | 201841012018-FORM-26 [03-05-2018(online)].pdf | 2018-05-03 |
| 8 | Correspondence by Agent_Form26,Proof of Right_07-05-2018.pdf | 2018-05-07 |
| 9 | 201841012018-FORM 18 [17-12-2021(online)].pdf | 2021-12-17 |
| 10 | 201841012018-FER.pdf | 2022-01-27 |
| 11 | 201841012018-FER_SER_REPLY [26-07-2022(online)].pdf | 2022-07-26 |
| 12 | 201841012018-PatentCertificate20-11-2023.pdf | 2023-11-20 |
| 13 | 201841012018-IntimationOfGrant20-11-2023.pdf | 2023-11-20 |
| 1 | Search201841012018E_25-01-2022.pdf |