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A Composition For Stimulating Limb Regeneration In A Vertebrate And A Method Thereof

Abstract: A composition (10) for stimulating limb regeneration in a vertebrate is provided. The composition includes 0.04 percentage by weight vitamin A. The composition also includes 99.96 percentage by weight water. FIG. 1

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
02 June 2023
Publication Number
27/2023
Publication Type
INA
Invention Field
BIO-CHEMISTRY
Status
Email
Parent Application

Applicants

RASHMI SHARMA
2 SARASWATI NAGAR, NEAR MDSU, AJMER, RAJASTHAN, INDIA

Inventors

1. RASHMI SHARMA
2 SARASWATI NAGAR, NEAR MDSU, AJMER, RAJASTHAN, INDIA

Specification

Description:FIELD OF INVENTION
[0001] Embodiments of the present disclosure relate to the field of medicinal preparations, and more particularly to a composition for stimulating limb regeneration in a vertebrate and a method thereof.
BACKGROUND
[0002] Limbs are the extremities of a body that enable locomotion and perform various functions such as grasping, walking, and manipulating objects. In vertebrates, including humans, the limbs include an upper limb, such as an arm and a lower limb, such as a leg. Amputation or loss of the limbs may occur due to various reasons, including accidents, medical conditions like cancer, infection, vascular diseases, congenital anomalies and the like. The amputation may be partial, involving the removal of a portion of the limbs, or complete, involving the removal of the limbs entirely.
[0003] Loss of the limbs impacts the mobility, independence, and quality of life of a person. Artificial limbs came into the picture in such a scenario. The artificial limbs are designed to replace the limbs that are amputated, helping the person to restore mobility and assisting the person to perform day-to-day activities. There are some disadvantages associated with the artificial limbs. The artificial limbs may not be able to replicate the functionality of a natural limb completely, thereby limiting certain activities and movements. Additionally, the artificial limbs require regular maintenance, adjustments, and replacements due to wear and tear. The artificial limbs are expensive. Also, prolonged use of the artificial limbs develops skin issues and discomfort in users.
[0004] Hence, there is a need for an improved composition for stimulating limb regeneration in a vertebrate and a method thereof to address the aforementioned issue(s).
OBJECTIVE OF THE INVENTION
[0005] An objective of the invention is to provide a composition for stimulating limb regeneration in a vertebrate and a method to prepare the same.
BRIEF DESCRIPTION
[0006] In accordance with an embodiment of the present disclosure, a composition for stimulating limb regeneration in a vertebrate is provided. The composition includes 0.04 percentage by weight vitamin A. The composition also includes 99.96 percentage by weight water.
[0007] In accordance with another embodiment of the present disclosure, a method for preparing a composition for stimulating limb regeneration in a vertebrate is provided. The method includes pipetting 0.4 milli grams of vitamin A. The method also includes pipetting 1000 milli liters of water. The method further includes mixing the vitamin A and the water to obtain the composition for stimulating the limb generation in a vertebrate.
[0008] To further clarify the advantages and features of the present disclosure, a more particular description of the disclosure will follow by reference to specific embodiments thereof, which are illustrated in the appended figures. It is to be appreciated that these figures depict only typical embodiments of the disclosure and are therefore not to be considered limiting in scope. The disclosure will be described and explained with additional specificity and detail with the appended figures.
BRIEF DESCRIPTION OF THE DRAWINGS
[0009] The disclosure will be described and explained with additional specificity and detail with the accompanying figures in which:
[0010] FIG. 1 is a block diagram representation of a composition for stimulating limb regeneration in a vertebrate in accordance with an embodiment of the present disclosure;
[0011] FIG. 2 is an X-ray imagery of an anuran tadpole before an administration of the composition in accordance with an embodiment of the present disclosure;
[0012] FIG. 3 is an X-ray imagery of the anuran tadpole after the administration of the composition in accordance with an embodiment of the present disclosure; and
[0013] FIG. 4 is a flow chart representing the steps involved in a method of preparation of a composition for stimulating limb regeneration in a vertebrate in accordance with an embodiment of the present disclosure.
[0014] Further, those skilled in the art will appreciate that elements in the figures are illustrated for simplicity and may not have necessarily been drawn to scale. Furthermore, in terms of the construction of the device, one or more components of the device may have been represented in the figures by conventional symbols, and the figures may show only those specific details that are pertinent to understanding the embodiments of the present disclosure so as not to obscure the figures with details that will be readily apparent to those skilled in the art having the benefit of the description herein.
DETAILED DESCRIPTION
[0015] For the purpose of promoting an understanding of the principles of the disclosure, reference will now be made to the embodiment illustrated in the figures and specific language will be used to describe them. It will nevertheless be understood that no limitation of the scope of the disclosure is thereby intended. Such alterations and further modifications in the illustrated system, and such further applications of the principles of the disclosure as would normally occur to those skilled in the art are to be construed as being within the scope of the present disclosure.
[0016] The terms "comprises", "comprising", or any other variations thereof, are intended to cover a non-exclusive inclusion, such that a process or method that comprises a list of steps does not include only those steps but may include other steps not expressly listed or inherent to such a process or method. Similarly, one or more devices or sub-systems or elements or structures or components preceded by "comprises... a" does not, without more constraints, preclude the existence of other devices, sub-systems, elements, structures, components, additional devices, additional sub-systems, additional elements, additional structures, or additional components. Appearances of the phrase "in an embodiment", "in another embodiment" and similar language throughout this specification may, but not necessarily do, all refer to the same embodiment.
[0017] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by those skilled in the art to which this disclosure belongs. The system, methods, and examples provided herein are only illustrative and not intended to be limiting.
[0018] In the following specification and the claims, reference will be made to a number of terms, which shall be defined to have the following meanings. The singular forms “a”, “an”, and “the” include plural references unless the context clearly dictates otherwise.
[0019] Embodiments of the present disclosure relate to a composition for stimulating limb regeneration in a vertebrate and a method thereof. The composition includes 0.04 percentage by weight vitamin A. The composition also includes 99.96 percentage by weight water.
[0020] FIG. 1 is a block diagram representation of a composition (10) for stimulating limb regeneration in a vertebrate in accordance with an embodiment of the present disclosure. In one embodiment, the vertebrate may include a mammal. In such an embodiment, the vertebrate may include humans. In some embodiments, the vertebrate may include a reptile. In a specific embodiment, the vertebrate may include a bird. In one embodiment, the vertebrate may include a fish. In one embodiment, the limb regeneration may be a homeobox transformation. The composition (10) includes 0.04 percentage by weight vitamin A (20). The composition (10) also includes 99.96 percentage by weight water (30). In one embodiment, the water (30) and the vitamin A (20) may be mixed at atmospheric pressure. In some embodiments, the water (30) and the vitamin A (20) may be mixed at room temperature. In one embodiment, the composition (10) may be administered by at least one of parenteral administration and oral administration.
[0021] FIG. 2 is an X-ray imagery of an anuran tadpole before administration of the composition (10) in accordance with an embodiment of the present disclosure.
[0022] FIG. 3 is the X-ray imagery of the anuran tadpole after the administration of the composition (10) in accordance with an embodiment of the present disclosure.
[0023] FIG. 4 is a flow chart representing the steps involved in a method (100) of preparation of a composition for stimulating limb regeneration in a vertebrate in accordance with an embodiment of the present disclosure. The method (100) includes pipetting 0.4 milli grams of vitamin A in step 110. In one embodiment, the limb regeneration may be a homeobox transformation.
[0024] The method (100) also includes pipetting 1000 milli liters of water in step 120.
[0025] The method (100) further includes mixing the vitamin A and the water to obtain the composition for stimulating the limb generation in a vertebrate in step 130. In one embodiment, the vertebrate may include a mammal. In some embodiments, the vertebrate may include a reptile. In a specific embodiment, the vertebrate may include bird. In one embodiment, the vertebrate may include a fish. In one embodiment, the water and the vitamin A may be mixed at atmospheric pressure. In some embodiments, the water and the vitamin A may be mixed at room temperature. In one embodiment, the composition may be administered by at least one of parenteral administration and oral administration.
[0026] Various embodiments of the composition for stimulating limb regeneration in a vertebrate and a method thereof described above enable various advantages. The composition is capable of stimulating the limb regeneration in the vertebrates, thereby negating the need for artificial limbs. The composition is easy to prepare and ready to use. Also, the composition is capable of being administered orally as well as through injection, thereby making the administration of the composition hassle free.
[0027] It will be understood by those skilled in the art that the foregoing general description and the following detailed description are exemplary and explanatory of the disclosure and are not intended to be restrictive thereof. While specific language has been used to describe the disclosure, any limitations arising on account of the same are not intended.
[0028] The figures and the foregoing description give examples of embodiments. Those skilled in the art will appreciate that one or more of the described elements may well be combined into a single functional element. Alternatively, certain elements may be split into multiple functional elements. Elements from one embodiment may be added to another embodiment. For example, the order of processes described herein may be changed and are not limited to the manner described herein. Moreover, the actions of any flow diagram need not be implemented in the order shown; nor do all the acts need to be necessarily performed. Also, those acts that are not dependent on other acts may be performed in parallel with the other acts. The scope of embodiments is by no means limited by these specific examples.
, Claims:1. A composition (10) for stimulating limb regeneration in a vertebrate comprising:
characterized in that:
0.04 percentage by weight vitamin A (20); and
99.96 percentage by weight water (30).
2. The composition (10) as claimed in claim 1, wherein the vertebrate comprises a mammal.
3. The composition (10) as claimed in claim 1, wherein the vertebrate comprises a reptile.
4. The composition (10) as claimed in claim 1, wherein the vertebrate comprises a bird.
5. The composition (10) as claimed in claim 1, wherein the limb regeneration comprises a homeobox transformation.
6. The composition (10) as claimed in claim 1, wherein the water (30) and the vitamin A (20) are mixed at atmospheric pressure.
7. The composition (10) as claimed in claim 1, wherein the water (30) and the vitamin A (20) are mixed at room temperature.
8. A method (100) of preparation of a composition for stimulating limb regeneration in a vertebrate comprising:
characterized in that:
pipetting 0.4 milli grams of vitamin A; (110)
pipetting 1000 milli litres of water; (120) and
mixing the vitamin A and the water to obtain the composition for stimulating the limb generation in a vertebrate. (130)
9. The method (100) as claimed in claim 8, wherein mixing the vitamin A and the water comprises mixing the vitamin A and the water at room temperature and pressure.
10. The method (100) as claimed in claim 8, comprising administering the composition comprises administering the composition by at least one of parenteral administration, and oral administration.

Dated this 02nd day of June 2023

Signature

Pachigolla Satya Pavan Kumar
IN/PA 2994
Agent for the Applicant

Documents

Orders

Section Controller Decision Date
sec.15 VARAPRASAD KUKATLA 2024-10-18
77 VARAPRASAD KUKATLA 2025-01-23

Application Documents

# Name Date
1 202311038179-STATEMENT OF UNDERTAKING (FORM 3) [02-06-2023(online)].pdf 2023-06-02
2 202311038179-REQUEST FOR EARLY PUBLICATION(FORM-9) [02-06-2023(online)].pdf 2023-06-02
3 202311038179-PROVISIONAL SPECIFICATION [02-06-2023(online)].pdf 2023-06-02
4 202311038179-POWER OF AUTHORITY [02-06-2023(online)].pdf 2023-06-02
5 202311038179-FORM-9 [02-06-2023(online)].pdf 2023-06-02
6 202311038179-FORM 1 [02-06-2023(online)].pdf 2023-06-02
7 202311038179-DRAWINGS [02-06-2023(online)].pdf 2023-06-02
8 202311038179-DECLARATION OF INVENTORSHIP (FORM 5) [02-06-2023(online)].pdf 2023-06-02
9 202311038179-COMPLETE SPECIFICATION [02-06-2023(online)].pdf 2023-06-02
10 202311038179-FORM 18A [05-06-2023(online)].pdf 2023-06-05
11 202311038179-FER.pdf 2023-08-03
12 202311038179-OTHERS [03-10-2023(online)].pdf 2023-10-03
13 202311038179-FORM 3 [03-10-2023(online)].pdf 2023-10-03
14 202311038179-FER_SER_REPLY [03-10-2023(online)].pdf 2023-10-03
15 202311038179-US(14)-HearingNotice-(HearingDate-23-11-2023).pdf 2023-11-01
16 202311038179-Correspondence to notify the Controller [16-11-2023(online)].pdf 2023-11-16
17 202311038179-FORM-26 [23-11-2023(online)].pdf 2023-11-23
18 202311038179-FORM-26 [23-11-2023(online)]-1.pdf 2023-11-23
19 202311038179-Written submissions and relevant documents [30-11-2023(online)].pdf 2023-11-30
20 202311038179-US(14)-ExtendedHearingNotice-(HearingDate-03-04-2024).pdf 2024-03-08
21 202311038179-Correspondence to notify the Controller [22-03-2024(online)].pdf 2024-03-22
22 202311038179-Power of Attorney [28-03-2024(online)].pdf 2024-03-28
23 202311038179-Covering Letter [28-03-2024(online)].pdf 2024-03-28
24 202311038179-Written submissions and relevant documents [18-04-2024(online)].pdf 2024-04-18
25 202311038179-RELEVANT DOCUMENTS [14-11-2024(online)].pdf 2024-11-14
26 202311038179-FORM-26 [14-11-2024(online)].pdf 2024-11-14
27 202311038179-FORM-24 [14-11-2024(online)].pdf 2024-11-14
28 202311038179-ReviewPetition-HearingNotice-(HearingDate-26-12-2024).pdf 2024-11-26
29 202311038179-FORM-26 [04-12-2024(online)].pdf 2024-12-04
30 202311038179-Correspondence to notify the Controller [26-12-2024(online)].pdf 2024-12-26
31 202311038179-Written submissions and relevant documents [09-01-2025(online)].pdf 2025-01-09

Search Strategy

1 PATSEERE_03-08-2023.pdf