Abstract: The present disclosure provides a crystalline form of orlistat, particularly form A of orlistat. The characterization of said form is performed using X-ray diffraction studies, IR and Differntial Scanning Calorimetry melting endotherm studies. Also, the disclosure provides a simple process to arrive at said crystalline form.
The present invention relates to the new polymorph and process for the preparation of Orlistat which is known by chemical name N-Formyl-L-leucine (1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester which inhibits pancreas lipase and used in the control obesity and hyperlipidemia.
| Section | Controller | Decision Date |
|---|---|---|
| # | Name | Date |
|---|---|---|
| 1 | 138-CHE-2009_EXAMREPORT.pdf | 2016-07-02 |
| 1 | Form-5.pdf | 2011-09-02 |
| 2 | 138-CHE-2009-Correspondence-170216.pdf | 2016-02-17 |
| 2 | Form-3.pdf | 2011-09-02 |
| 3 | Form-1.pdf | 2011-09-02 |
| 3 | 138-CHE-2009-Correspondence-020915.pdf | 2015-09-07 |
| 4 | Drawings.pdf | 2011-09-02 |
| 4 | 138-CHE-2009-Form 1-020915.pdf | 2015-09-07 |
| 5 | 138-CHE-2009-Form 13-020915.pdf | 2015-09-07 |
| 5 | 138-CHE-2009 FORM-3 08-11-2011.pdf | 2011-11-08 |
| 6 | 138-CHE-2009 CORRESPONDENCE OTHERS 20-02-2015.pdf | 2015-02-20 |
| 6 | 138-CHE-2009 CORRESPONDENCE OTHERS 08-11-2011.pdf | 2011-11-08 |
| 7 | Abstract (Marked & Clear Version).pdf | 2014-12-23 |
| 7 | 138-CHE-2009 FORM-13 13-07-2012.pdf | 2012-07-13 |
| 8 | Claims (Marked & Clear version.pdf | 2014-12-23 |
| 8 | 138-CHE-2009 FORM-1 13-07-2012.pdf | 2012-07-13 |
| 9 | 138-CHE-2009 CORRESPONDENCE OTHERS 13-07-2012.pdf | 2012-07-13 |
| 9 | Complete Specification.pdf | 2014-12-23 |
| 10 | 138-CHE-2009 OTHER PATENT DOCUMENT 15-12-2014.pdf | 2014-12-15 |
| 10 | Drawings & PoA.pdf | 2014-12-23 |
| 11 | 138-CHENP-2009 POWER OF ATTORNEY 17-12-2014.pdf | 2014-12-17 |
| 11 | Office Actions of corresponding Patent Applications.pdf | 2014-12-23 |
| 12 | 138-CHENP-2009 FORM-3 17-12-2014.pdf | 2014-12-17 |
| 12 | Petition under Rule 137.pdf | 2014-12-23 |
| 13 | 138-CHENP-2009 EXAMINATION REPORT REPLY RECEIVED 17-12-2014.pdf | 2014-12-17 |
| 13 | Response to FER.pdf | 2014-12-23 |
| 14 | 138-CHENP-2009 AMENDED CLAIMS 17-12-2014.pdf | 2014-12-17 |
| 14 | 138-CHENP-2009 AMENDED PAGES OF SPECIFICATION 17-12-2014.pdf | 2014-12-17 |
| 15 | 138-CHENP-2009 AMENDED CLAIMS 17-12-2014.pdf | 2014-12-17 |
| 15 | 138-CHENP-2009 AMENDED PAGES OF SPECIFICATION 17-12-2014.pdf | 2014-12-17 |
| 16 | 138-CHENP-2009 EXAMINATION REPORT REPLY RECEIVED 17-12-2014.pdf | 2014-12-17 |
| 16 | Response to FER.pdf | 2014-12-23 |
| 17 | Petition under Rule 137.pdf | 2014-12-23 |
| 17 | 138-CHENP-2009 FORM-3 17-12-2014.pdf | 2014-12-17 |
| 18 | 138-CHENP-2009 POWER OF ATTORNEY 17-12-2014.pdf | 2014-12-17 |
| 18 | Office Actions of corresponding Patent Applications.pdf | 2014-12-23 |
| 19 | 138-CHE-2009 OTHER PATENT DOCUMENT 15-12-2014.pdf | 2014-12-15 |
| 19 | Drawings & PoA.pdf | 2014-12-23 |
| 20 | 138-CHE-2009 CORRESPONDENCE OTHERS 13-07-2012.pdf | 2012-07-13 |
| 20 | Complete Specification.pdf | 2014-12-23 |
| 21 | 138-CHE-2009 FORM-1 13-07-2012.pdf | 2012-07-13 |
| 21 | Claims (Marked & Clear version.pdf | 2014-12-23 |
| 22 | 138-CHE-2009 FORM-13 13-07-2012.pdf | 2012-07-13 |
| 22 | Abstract (Marked & Clear Version).pdf | 2014-12-23 |
| 23 | 138-CHE-2009 CORRESPONDENCE OTHERS 08-11-2011.pdf | 2011-11-08 |
| 23 | 138-CHE-2009 CORRESPONDENCE OTHERS 20-02-2015.pdf | 2015-02-20 |
| 24 | 138-CHE-2009 FORM-3 08-11-2011.pdf | 2011-11-08 |
| 24 | 138-CHE-2009-Form 13-020915.pdf | 2015-09-07 |
| 25 | Drawings.pdf | 2011-09-02 |
| 25 | 138-CHE-2009-Form 1-020915.pdf | 2015-09-07 |
| 26 | Form-1.pdf | 2011-09-02 |
| 26 | 138-CHE-2009-Correspondence-020915.pdf | 2015-09-07 |
| 27 | Form-3.pdf | 2011-09-02 |
| 27 | 138-CHE-2009-Correspondence-170216.pdf | 2016-02-17 |
| 28 | Form-5.pdf | 2011-09-02 |
| 28 | 138-CHE-2009_EXAMREPORT.pdf | 2016-07-02 |