DESC:FIELD OF THE INVENTION:
The present invention relates to granular agrochemical composition comprising Gibberellic acid for promoting plant health comprising bioactive amounts of (A) Gibberellic acid; (B) one or more of active ingredients selected from class of an insecticide; or a fungicide; or a plant health additive; or combination thereof. The present invention further relates to process of preparing said composition along with at least one inactive excipients and granular formulation thereof for soil application.

BACKGROUND OF THE INVENTION:
Plant Growth Regulators (PGRs) are typically any substance or mixture of substances intended to accelerate or slow down the rate of growth or ripening, or otherwise change the development of plants, or to produce plants. Some plant growth regulators protect plants from abiotic stress. They give tolerance to extreme temperatures, both high and low, to drought, to high salt content, which are some examples of abiotic stresses that plants can undergo. PGR allows plants to withstand abiotic stresses by controlling the natural expression of hormones in the plant. Gibberellic Acid is applied to growing crops (field crops, small fruits, vines and tree fruits), ornamental and shade tress, and ornamental plants, shrubs and vines. It is a pentacyclic diterpene plant hormone or plant growth regulator. It is familiar for its role in increasing reproductive growth, cell elongation, seed germination, dormancy, reproductive growth, tolerance against various environmental stresses, and senescence. The seed quality parameters has been analysed in Coriander seeds. The authors reported that primed seeds with Gibberellic acid significantly increased the germination as well as vigour parameters.
The oral toxicity of Gibberellic acid (GA3) has been evaluated in S. littoralis and L.migratoria insect species. Researchers observed that GA3 caused significant reduction in food consumption in both insect species which led to larval weight loss. GA3 toxicity was also demonstrated by larval mortality due to exuviation difficulties.

Combination of pesticides are used to broaden the spectrum of control of insects-pests -mite-fungal-bacterial and nematode, and diseases, to improve the pest and disease control with synergistc effect, reduce dosage, thereby reducing environmental impact, to broaden the spectrum of control, i.e. chewing and sucking insects at a time, decrease chances of development and management of resistance and to enhance residual control so lesser the number of sprays for crop protections and minimizing the pesticidal load in ecosystem. The combination of pesticides at times demonstrate an additive or synergistic effect that results in an improved control on the insects-pests -mite-fungal-bacterial and nematode, and diseases.

Pesticides are used widely and very frequently in commercial agriculture
and have enabled an enormous increase in crop yields and product quality which
ultimately increased the ease to farmers in term of economic advantage as well as ease of farming activities.

There are many combinations of one plant growth regulator along with pesticides known in the art for the control of insects-pests. For example, RU2444896C2 patent relates to compositions and methods for controlling plant germination and growth and for controlling plant diseases by treating plants or plant propagation material with at least one plant growth regulator, individually or in combination with at least one plant activator, and / or other active substances. The patent more specifically relates to a composition comprising acibenzolar-S-methyl, probenazole, harpin protein and extract of Reynoutria sachalinensis (reysa) along with plant growth regulators.

KR20130080441A patent relates to (a) at least one pesticide effective amount of a compound of formula (I) wherein Q is i, ii or iii) or an agrochemically acceptable salt or N-oxide thereof; And (b) a plant growth regulator, wherein the ratio of the compound of formula I to the plant growth regulator is 20: 1 to 1:25.

WO2014079841A1 patent relates to pesticidal mixtures comprising one biological compound and at least one fungicidal, insecticidal or plant growth regulating compound.

WO2021191915A1 patent relates to a pesticidal composition comprising elemental sulphur, at least one anthranilic diamide insecticide, and at least one agrochemically acceptable excipient. The invention particularly relates to a pesticidal composition comprising elemental sulphur in the range of 40%w/w to 95%w/w of the total composition; at least one anthranilic diamide insecticide selected from the group consisting of cyantraniliprole, tetraniliprole, cyclaniliprole, tetrachlorantraniliprole and chlorantraniliprole present in the range of 0.1%w/w to 3%w/w of the total composition; and at least one agrochemically acceptable excipient.
Insecticidal Activity of Gibberellic Acid against
Spodoptera littoralis (Lepidoptera, Noctuidae) and
Locusta migratoria migratoria (Orthoptera, Acrididae)
Insecticidal Activity of Gibberellic Acid against
Spodoptera littoralis (Lepidoptera, Noctuidae) and
Locusta migratoria migratoria (Orthoptera, Acrididae)
Abdellaoui Khemais et al.; ‘Insecticidal activity of Gibberellic acid against Spodoptera littoralis (Lepidoptera, Noctuidae) and Locusta migratoria migratoria (Orthoptera, Acrididae)’,Pest Technology 3 (1), 28-33, 2009 relates to Gibberellic acid (GA), a plant growth regulator, shows oral toxicity on insects. When insects were exposed to various concentrations of GA incorporated into the diet, GA3 significantly reduced food consumption of both insect species leading to larval weight loss. GA3 toxicity was also demonstrated by some larval mortality caused by exuviation difficulties. Different types of malformations observed were due to difficulties in rejecting the nymphal integuments. Additionally, digestive tract softness, particularly for L. migratoria, was observed. A subsequent histological study of the foregut and gastric caeca revealed the cytotoxic effect of GA3 on insect. Further GA3 was found to be associated with the destruction of epithelial cells and a total disorganization of the cellular structure of these organs. Consequently, this experiment led us to conclude that ingested GA3 caused perturbation in development and death of both insect species, which may be caused by antifeedant properties and by cytotoxic effect via alteration of the digestive system.

There is however a need for improvement of these combinations. Single active combinations used over a long period of time has resulted in resistance. With the onset of resistance to certain pests, there is a need in the art for a combination of actives that decreases chances of resistance and improves the spectrum of disease and pest control.

However still there is a need for a composition comprising A) gibberellic acid; and B) one or more of active ingredients selected from class of an insecticide; or a fungicides; or a plant health additive; or combination thereof which overcomes some of the existing problems and can be prepared easily without much complex manufacturing process.

Therefore, one object of the present invention is combining Gibberellic acid and pesticide(s) which will increase the overall yield of plants/crops as Gibberellic acid regulates growth, increases tolerance to abiotic stress and pesticides control insect-pest-mite-fungal-bacterial and nematode.
Yet another object of the present invention is to provide improved combinations of pesticides that promote plant health.
Yet another object of the present invention is to provide granular formulation which is specifically for soil application.
Embodiment of the present invention can ameliorate one or more of the above mentioned problems.

Inventors of the present invention have surprisingly found that the novel granular agrochemical composition comprising Gibberellic acid for promoting plant health embodying (A) gibberellic acid; and (B) one or more of active ingredients selected from class of an insecticide; or a fungicides; or a plant health additive; or combination thereof as described herein which can provide solution to the above mentioned problems.

SUMMARY OF THE INVENTION
Therefore an aspect of the present invention provides granular agrochemical composition comprising Gibberellic acid for promoting plant health comprising bioactive amounts of (A) gibberellic acid; and (B) one or more of active ingredients selected from class of an insecticide; class of fungicides; or a plant health additive; or combination thereof.
Further aspect of the present invention provides granular agrochemical composition comprising Gibberellic acid for promoting plant health comprising insecticides selected from the class carbamates, organophosphates, Phenylpyrazoles, Pyrethroids, neonicotinoids, Spinosyns, Mectins, Juvenile hormone mimics, Chordotonal organs modulators, mite growth inhibitors, Microbial disruptors of insect midgut membrane, Inhibitors of mitochondrial ATP synthase, Uncouplers of oxidative phosphorylation, Nereis toxin, Chitin biosynthesis inhibitors, Inhibitors of the chitin biosynthesis type 1, Moulting disruptors, Ecdyson receptor agonists, Octopamin receptor agonists, METI (mitochondrial electron transport inhibitors), Voltage-dependent sodium channel blockers, Lipid synthesis, inhibitors of acetyl CoA carboxylase, Diamides, Metadiamides, Isoxazolines, Baculoviruses and Compounds of unknown or uncertain mode of action.
Further aspect of the present invention provides granular agrochemical composition comprising Gibberellic acid for promoting plant health comprising fungicides selected from the class Nucleic acid synthesis inhibitors, Cytoskeleton and motor proteins/cell division Inhibitors, Respiration inhibitors, Amino acids and protein synthesis inhibitors, Signal transduction inhibitors, Lipid or transport and membrane synthesis inhibitors, Sterol biosynthesis Inhibitors, Cell wall biosynthesis Inhibitors, Melanin synthesis in cell wall Inhibitors, Plant defence inducers, Unknow mode of action, Not classified (N), Fungicides with multisite activities (M)-multisite contact activities and Biologicals with multiple modes of action (BM).
Further aspect of the present invention provides granular agrochemical composition comprising Gibberellic acid for promoting plant health comprising plant health additives selected from the class bio-stimulants, plant growth regulators, microbial agents and micronutrients or mixture thereof.
Accordingly, in a further aspect, the present invention provides a method of protecting a plant propagation material, a plant, parts of a plant and/or plant organs that grow at a later point in time against pathogenic damage or insect-pest damage by applying to the plant propagation material a composition comprising a pesticidal composition defined in the first aspect.
As per one embodiment, formulation for the agrochemical composition is selected from Granule (GR), Soil Applied Granules (SAG) and Controlled release granules (CR) may be slow release granule or fast release granules; and one or more inactive excipients such as a) dispersant b) wetting agent c) solvent d) carrier e) colouring agent and f) controlled release agent.

DETAILED DESCRIPTION OF THE INVENTION:
The term "Bioactive amounts” as mentioned herein means that amount which, when applied treatment of crops, is sufficient to effect such treatment.
Therefore an aspect of the present invention provides synergistic agrochemical composition comprising Gibberellic acid for promoting plant health comprising bioactive amounts of (A) gibberellic acid; and (B) one or more of active ingredients selected from class of an insecticide; class of fungicides; or a plant health additive; or combination thereof.
In an embodiment of the present invention, insecticides are selected from the class carbamates, organophosphates, Phenylpyrazoles, Pyrethroids, neonicotinoids, Spinosyns, Mectins, Juvenile hormone mimics, Chordotonal organs modulators, mite growth inhibitors, Microbial disruptors of insect midgut membrane, Inhibitors of mitochondrial ATP synthase, Uncouplers of oxidative phosphorylation, Nereis toxin, Chitin biosynthesis inhibitors, Inhibitors of the chitin biosynthesis type 1, Moulting disruptors, Ecdyson receptor agonists, Octopamin receptor agonists, METI (mitochondrial electron transport inhibitors), Voltage-dependent sodium channel blockers, Lipid synthesis, inhibitors of acetyl CoA carboxylase, Diamides, Metadiamides, Isoxazolines, Baculoviruses and Compounds of unknown or uncertain mode of action.
In another embodiment of the present invention, fungicides are selected from the class Nucleic acid synthesis inhibitors, Cytoskeleton and motor proteins/cell division Inhibitors, Respiration inhibitors, Amino acids and protein synthesis inhibitors, Signal transduction inhibitors, Lipid or transport and membrane synthesis inhibitors, Sterol biosynthesis Inhibitors, Cell wall biosynthesis Inhibitors, Melanin synthesis in cell wall Inhibitors, Plant defence inducers, Unknow mode of action, Not classified (N), Fungicides with multisite activities (M)-multisite contact activities and Biologicals with multiple modes of action (BM).
In another embodiment of the present invention, plant health additives are selected from the class bio-stimulants, plant growth regulators, microbial agents and micronutrients or mixture thereof.
In an embodiment of the present invention the insecticide from class of a Carbamates may be selected from carbaryl, carbofuran, carbosulfan, methomyl, oxamyl, pirimicarb, thiodicarb.
In an embodiment of the present invention the insecticide from class of a Organophosphates may be selected from acephate, cadusafos, chlorpyrifos, chlorpyrifos-methyl, demeton-S-methyl, dimethoate, ethion, fenamiphos, fenitrothion, fenthion, fosthiazate, methamidophos, monocrotophos, oxydemeton-methyl, parathion, parathion-methyl, phenthoate, phorate, phosalone, phosphamidon, profenofos, quinalphos, triazophos.
In an embodiment of the present invention the insecticide from class of Phenylpyrazoles may be selected from ethiprole, fipronil, flufiprole, nicofluprole, pyrafluprole, pyriprole.
In an embodiment of the present invention the insecticide from the class of Pyrethroids may be selected from bifenthrin, cyfluthrin, beta-cyfluthrin, cyhalothrin, lambda-cyhalothrin, gamma-cyhalothrin, cypermethrin, alpha-cypermethrin, beta-cypermethrin, theta-cypermethrin, zeta-cypermethrin, cyphenothrin, deltamethrin, fenpropathrin, fenvalerate, tau-fluvalinate, permethrin, phenothrin, prallethrin, profluthrin, pyrethrin (pyrethrum).
In an embodiment of the present invention the insecticide from the class of Nicotinic insecticides:- neonicotinoids may be selected from acetamiprid, clothianidin, dinotefuran, imidacloprid, nitenpyram, thiacloprid, thiamethoxam, flupyrimin, cycloxaprid, paichongding, guadipyr, cycloxylidin; sulfoximines-sulfoxaflor; butenolides- flupyradifurone; mesoionics- triflumezopyrim, dichloromezotiaz, fenmezoditiaz.
In an embodiment of the present invention the insecticide from the class of Spinosyns are spinosad and spinetoram.
In an embodiment of the present invention the insecticide from the class of Mectins may be selected from Avermectins-abamectin, emamectin benzoate, ivermectin, lepimectin; milbemycins- milbemectin.
In an embodiment of the present invention the insecticide from the class of Juvenile hormone mimics may be selected from hydroprene, kinoprene, methoprene, fenoxycarb, pyriproxyfen.
In an embodiment of the present invention the insecticide from the class of Chordotonal organs modulators may be selected from pymetrozine, pyrifluquinazon; afidopyropen, flonicamid.
In a further embodiment of the present invention the insecticide from the class of Mite growth inhibitors may be selected from clofentezine, hexythiazox, diflovidazin, etoxazole.
In a further embodiment of the present invention the insecticide from the class of Microbial disruptors of insect midgut membrane are Bacillus thuringiensis and insecticidal proteins.
In a further embodiment of the present invention the insecticide from the class of Inhibitors of mitochondrial ATP synthase may be selected from diafenthiuron, azocyclotin, cyhexatin, fenbutatin oxide, propargite, tetradifon.
In a further embodiment of the present invention the insecticide from the class of Uncouplers of oxidative phosphorylation may be selected from chlorfenapyr, DNOC, sulfluramid.
In a yet another embodiment of the present invention the insecticide from the class of Nereis toxin may be selected from bensultap, monosultap, cartap hydrochloride, thiocyclam, thiocyclam hydrogen oxalate, thiocyclam hydrochloride, thiosultap sodium.
In a yet another embodiment of the present invention the insecticide from the class of Chitin biosynthesis inhibitors may be selected from benzoylureas-bistrifluron, chlorfluazuron, diflubenzuron, flucycloxuron, flufenoxuron, hexaflumuron, lufenuron, novaluron, noviflumuron, teflubenzuron, triflumuron.
In a yet another embodiment of the present invention the insecticide from Inhibitors of the chitin biosynthesis type 1 is buprofezin.

In a yet another embodiment of the present invention the insecticide from Moulting disruptors is cyromazine;
In a yet another embodiment of the present invention the insecticide from the class of Ecdyson receptor agonists may be selected from the diacylhydrazines- methoxyfenozide, tebufenozide, halofenozide, fufenozide, chromafenozide.
In a yet another embodiment of the present invention the insecticide from the class of Octopamin receptor agonists is amitraz.
In a yet another embodiment of the present invention the insecticide from the class of METI (mitochondrial electron transport inhibitors may be selected from fenazaquin, fenpyroximate, pyrimidifen, pyridaben, tebufenpyrad, tolfenpyrad, flufenerim, rotenone, cyenopyrafen, cyflumetofen, pyflubumidemm, hydramethylnon, acequinocyl, flometoquin, fluacrypyrim, pyriminostrobin, bifenazate.
In a yet another embodiment of the present invention the insecticide from Voltage-dependent sodium channel blockers may be selected from indoxacarb and metaflumizone.
In a yet another embodiment of the present invention the insecticide from class of Lipid synthesis, inhibitors of acetyl CoA carboxylase may be selected from Tetronic and tetramic acid derivatives-spirodiclofen, spiromesifen, spirotetramat, spidoxamat, spiropidion.
In a yet another embodiment of the present invention the insecticide from class of Diamides may be selected from chlorantraniliprole, cyantraniliprole, cyclaniliprole, tetraniliprole, tetrachlorantraniliprole, tyclopyrazoflor, cyhalodiamide, flubendiamide, fluchlordiniliprole.
In a yet another embodiment of the present invention the insecticide from class of Metadiamides are broflanilide, cyproflanilide.
In a yet another embodiment of the present invention the insecticide from class of Isoxazolines may be selected from fluxametamide, isocycloseram, afoxolaner, esafoxolaner, fluralaner, lotilaner, sarolaner.
In a yet another embodiment of the present invention the insecticide from class of Baculoviruses are granuloviruses and nucleopolyhedrosis viruses.
In a yet another embodiment of the present invention the insecticide from class of Compounds of unknown or uncertain mode of action may be selected from benzpyrimoxan, pyridalyl, oxazosulfyl, dimpropyridaz, acaricidal compounds-fluhexafon, cyetpyrafen, flupentiofenox, acyonapyr; nematicidal compounds-cyclobutrifluram, fluazaindolizine, tioxazafen.
In another embodiment of the present invention the fungicide from class of Nucleic acid synthesis inhibitors may be selected from Phenyl Amides group (A1)-Acylalanines-benalaxyl, benalaxyl-M (=kiralaxyl), furalaxyl, metalasxyl, metalaxyl-M (=mefenoxam)), butyrolactones(ofurace),oxazolidinones (oxadixyl),hydroxy-(2-amino-) pyrimidines; A2. bupirimate, dimethirimol, ethirimol, heteroaromatics; (A3)-isothiazolones-octhilinone, isoxazoles-hymexazole; carboxylic acids(A4)-oxolinic acid; Other-5-fluorocytosine, 5- fluoro-2-(p-tolylmethoxy)pyrimidin-4-amine, 5-fluoro-2-(4-fluorophenylmethoxy)pyrimidin-4-amine.
In another embodiment of the present invention the fungicide from class of Cytoskeleton and motor proteins/cell division Inhibitors may be selected from benzimidazoles(B1)-benomyl, carbendazim, fuberidazole, thiabendazole; thiophanates(B1)-thiophanate, thiophanate-methyl; N-phenyl carbamates(B2)-diethofencarb; toluamides(B3)-zoxamide; ethylamino-thiazole-carboxamide (B3)-ethaboxam; phenylureas (B4)-pencycuron; pyridinylmethyl benzamides (B5)-fluopicolide, flufenoxadiazam, fluopimomide; aminocyanoacrylates (B6)-phenamacril; benzophenone(B6)-metrafenone; benzoylpyridine(B6)-pyriofenone.
In another embodiment of the present invention the fungicide from class of Respiration inhibitors may be selected from Pyrimidinamines(C1)-diflumetorim; pyrazole-5-carboxamide(C1)-tolfenpyrad; quinazoline(C1)-fenazaquin; SDHI (Succinate dehydrogenase inhibitors) (C2)-phenyl-benzamides(C2)-benodanil, flutolanil, mepronil; phenyl-oxo-ethyl thiophene amid(C2)-isofetamid; pyridinyl-ethyl-benzamides(C2)-fluopyram; furan-carboxamides(C2)-fenfuran; oxathin-carboxamides(C2)-carboxin, oxycarboxin, thiazole-carboxamides(C2)-thifluzamide; pyrazole-4-carboxamides(C2)-benzovindiflupyr, bixafen, fluindapyr, fluxapyroxad, furametpyr, isopyrazam, penflufen, penthiopyrad, sedaxane, flubeneteram, pyrapropoyne, inpyrfluxam, isoflucypram, pydiflumetofen; pyridine carboxamides(C2)-boscalid, pyraziflumid; QoI-fungicides (Quinone outside Inhibitors) (C3)-benzyl carbamates-pyribencarb; dihydro dioxazines-fluoxastrobin; imidazolinones-fenamidone; methoxy acetamide; mandestrobin; methoxy acrylates-azoxystrobin, coumoxystrobin, enoxastrobin, flufenoxystrobin, picoxystrobin, pyraoxystrobin; methoxy carbamates-pyraclostrobin, pyrametostrobin, triclopyricarb; oxazolidine diones-famoxadone; oximino acetamides-dimoxystrobin, fenamistrobin, metominostrobin, orysastrobin; oximino acetates-kresoxim methyl, trifloxystrobin; QiI-fungicides (Quinone inside Inhibitors) (C4)-cyano imidazole-cyazofamid; sulfamoyl triazole-amisulbrom; picolinamides-fenpicoxamid, florylpicoxamid, metarylpicoxamid; tetrazolinones-metyltetraprole; uncouplers of oxidative phosphorylation (C5)-dinitophenyl crotonates (C5)-binapacryl, meptyldinocap, dinocap, 2,6-dinitro anilines (C5)-fluazinam, inhibitors of oxidative phosphorylation,ATP synthase (C6)-tri phenyl tin compounds (C6)-fentin acetate, fentin chloride, fentin hydroxide, ATP transport(C7)-thiophene (C7)-silthiofam, Quinone outside Inhibitors,stigmatellin binding type (QoSI-C8) triazolo pyrimidylamine (C8)-ametoctradin.
In another embodiment of the present invention the fungicide from class of Amino acids and protein synthesis inhibitors may be selected from anilino-pyrimidines (D1)-cyprodinil, mepanipyrim, pyrimethanil, enopyranuronic acid antibiotic (D2)-blasticidin-S, hexopyranosyl antibiotic (D3)-kasugamycin, glucopyranosyl antibiotic (D4)-streptomycin, tetracycline antibiotic (D5)-oxytetracycline.
In another embodiment of the present invention the fungicide from class of Signal transduction inhibitors may be selected from aryloxyquinoline (E1)-quinoxyfen, quinazolinone (E1)-proquinazid, phenylpyrroles (E2)-fenpiclonil, fludioxonil, dicarboximides (E3)-chlozolinate, dimethachlone, iprodione, procymidone, vinclozolin.
In another embodiment of the present invention the fungicide from class of Lipid or transport and membrane synthesis inhibitors may be selected from dithiolanes (F2)-isoprothiolane, phosphorthiolates(F2)-edifenphos, iprobenfos (IBP), pyrazophos, aromatic hydrocarbons (F3)-biphenyl, chloroneb, dicloran, quintozene, tecnazene, tolcofos methyl, etridiazole, carbamates (F4)-iodocarb, propamocarb, prothiocarb, terpene hydrocarbons (F7)-extract from Melaleuca arternifolia (tea tree), plant oils (mixtures); eugenol, geraniol, thymol, amphoteric macrolide antifungal (F8)-natamycin (pimaricin), piperidinyl thiazole isoxazolines (F9)-oxathiapipronil, fluoxapipronil, Fluoxapiprolin-s.
In another embodiment of the present invention the fungicide from class of Sterol biosynthesis Inhibitors may be selected from imidazoles(G1)-imazalil, imidazoles(G1)-oxpoconazole, pefurazoate, procloraz, triflumizole, piperazines-triforine, pyridines-pyrifenox, pyrisoxazole, pyrimidines-fenarimo, naurimol, triazoles-azaconazole, bitertanol, bromuconazole, cyproconazole, difenoconazole, diniconazole, epoxiconazole, etaconazole, fenbuconazole, fluquinconazole, flusilazole, frutriafol, hexaconazole, imibenconazole, ipconazole, mefentrifluconazole, metconazole, myclobutanil, penconazole, propiconazole, prothioconazole, simconazole, tebuconazole, tetraconazole, tiradimefon, tiradimenol, triticonazole, fluoxytioconazole, morpholines (G2)-aldimoprh, dedomorph, tridemorph, fenpropimorph, piperidines (G2)-fenpropidin, piperalin, spiroketal amines (G2)-spiroxamine, amino pyrazolinone (G3)-fenpyrazamine, hydroxyanilides (G3)-fenhexamid, allaylamines (G4)-naftifine, terbinafine, pyributicarb.
In another embodiment of the present invention the fungicide from class of Cell wall biosynthesis Inhibitors may be selected from peptidpyl pyrimidine (H4)-polyoxin, cinnamic acid amides (H5)-dimethomorph, flumorph, pyrimorph, mandelic acid amides (H5)-mandipropamid, valinamide carbamates (H5)-benthiavalicard, iprovalicarb, alifenalate.
In another embodiment of the present invention the fungicide from the class of Melanin synthesis in cell wall Inhibitors may be selected from isobenzo furanone (I1)-fthalide, pyrrolo quinolinone-pyroquilon, triazolobenzothiazole-tricyclazole, carboxamide (I2)-diclycymet, cyclopropane carboxamide (I2)-carpropamid, propionamide(I2)-fenoxanil, trifluoroethyl carbamate (I3)-tolprocarb.
In another embodiment of the present invention the fungicide from the class of Plant defence inducers may be selected from benzothiadiazole (P1)-acibenzolar-S-methyl, probenazole, thiadiazole (P3)-tiadinil, isotianil, polysaccharides (P4)-laminarin, complex mixture thanol extract (P5)- extract from Reynoutria sachalinensis (giant knowweed), bacterial Bacillus (P6)-Bacillus mycoides isolate J, cell awall of Saccharomyces erevisiae strain LAS117, phosphonates(P7)-fosetyl-AL, phosphoric acid and salts.
In another embodiment of the present invention the fungicide from the class of Unknow mode of action may be selected from cyanoacetamide oxime-cymoxanil, phthalamic acid-teclofthalam, benzotirazines-triazoxide, benzene-sulfonamides-fluslfamide, pyridazinones-diclomezine, phenyl acetamide-cyflufenamid, guanindines-dodine, cyano methylene thiazolidines-flutianil, pyrimidinone hydrazones-ferimzone, flumetylsulforim, 4-quinolyl acetates-tebufloquin, tetrazolyloximes-picarbutrazox, glucopyranosyl antibiotics-validamycin.
In another embodiment of the present invention the fungicide from the class of not classified (N) may be selected from mineral oils, inorganic oils, organic oils, potassium bicarbonates, materials of biological origin.
In another embodiment of the present invention the fungicides with multisite activities (M)-multisite contact activities may be selected from inorganic-copper (copper hydroxide, copper oxychloride, copper (II) sulphate, Bordeaux mixture, copper salicylate, cuprous oxide), sulphur, dithiocarbamates and relatives-ferbam, mancozeb, maneb, metiram, propineb, thiram, zinc thiazole, zineb, ziram, phthalimides-captan, captafol, folpet, chloronitriles (phthalonitriles)-chlorothalonil, sulfamides-dichlofluanid, tolylfluanid, bis guanidines-guazatine, iminoctadine, triazines-anilazine, quinones (anthraquinones)-dithianon, quinoxalines-chinomethionat / quinomethionate, maleimide-fluoroimide, thiocarbamate-methasulfocarb.
In another embodiment of the present invention the fungicide from the class of Biologicals with multiple modes of action (BM) may be selected from polypeptide (lectin)-extract from the cotyledons of lupine plantlets (“BLAD”), Plant extract-Phenols, Sesquiterpenes, Triterpenoids, Coumarins, microbial (living microbes or extract metabilites-Trichoderma atroviride strain SC1, Trichoderma atroviride strain I-1237, Trichoderma atroviride strain LU132, Trichoderma asperellum strain T34, Gliocladium catenulatum strain J1446 , Clonostachys rosea strain CR-7 , Bacillus amyloliquefaciens strain QST713, strain FZB24, strain MBI600, strain D747, strain F727, Bacillus subtilis strain AFS032321, Pseudomonas chlororaphis strain AFS009, Streptomyces griseovirides strain K61, Streptomyces lydicus strain WYEC108.
In another embodiment of the present invention the other fungicides may be selected from Ipflufenoquin-quinoline fungicide, Pyridachlometyl-pyridazine fungicide, quinofumelin, dichlobentiazox, aminopyrifen, dipymetitrone, seboctylamine (bactericide), chloroinconazide (virucide).
In an embodiment of the present invention, the Plant health additives from the class of Bio stimulants may be selected from humic acid (salts), fulvic acid (salts), amino acids (alanine, arginine, aspartic acid, cysteine, glutamic acid, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, proline, serine, threonine, tryptophan, tyrosine, valine or mixture thereof), protein hydrolysates, peptides, organic acid, acetyl thioproline, thiazolidine carboxylic acid, jasmonic acid, methyl jasmonate, chitosan, chitin, alginate, cellulose, starch, cyclodextrin, probenazole, acibenzolar-s-methyl, seaweed extract (Ascophyllum nodosum), polyamines, silicic acid (salts)-orthosilicic acid (H4Si04), salicylic acid, lactic acid, phenyl lactic acid, fumaric acid, acibenzolar-s-methyl, nitrobenzene, (Homo)brassinolide, forchlorfenuron, triacontanol, nitrophenolate (sodium para-nitrophenolate, ortho-nitrophenolate, sodium-5-nitroguaiacolate or mixture thereof.
In an embodiment of the present invention plant health additives from the class of Plant growth regulators may be selected from Auxins: Indole acetic acid, Indole butyric acid, alpha-naphthyl acetic acid; Cytokinins: kinetin, zeatin, 6-benzylaminopurine, 6-benzyladenine, dipheylurea, thidiazuron, anisiflupurin; Ethylene modulators: aviglycine, prohexadione, prohexadione calcium, trinexapac, trinexapac-ethyl, aminoethoxyvinylglycine (AVG); Growth inhibitors: abscisic acid, chlorpropham, flumetralin, maleic hydrazide, mepiquat, mepiquat chloride, mepiquat pentaborate; Growth retardants: chlormequat, chlormequat chloride, paclobutrazol, uniconazole-P.
In yet another embodiment of the present invention, plant health additives from the class of Microbial agents may be selected from Rhizobium spp., Azotobacter spp., Azospirillum spp., Acetobacter spp., Bacillus megaterium var. phosphaticum, Bacillus polymyxa, Bacillus licheniformis, Frateuria aurantia, Thiobacillus thiooxidans, VAM (Vesicular Arbuscular Mycorrhiza) (Acaulospora spp., Gigaspora spp., Sclerocystis spp., Scutellospora spp., Glomus spp. Etc.), Acinetobacter calcoaceticus, Bacillus subtilis, Bacillus thuringiensis var. kurstaki, Pseudomonas fluorescens, Beauveria bassina, Metarrhizium anisopliae, Varticillium lecanii, Trichoderma viride, Trichoderma harzianum, Paecilomyces lilacinus, Trichoderma spp. etc. or mixture thereof.
In a further embodiment of the present invention plant health additives from the class of Micronutrients may be selected from zinc (zinc sulphate heptahydrate, zinc sulphate mono hydrate, Zn-EDTA, zinc oxide, zinc lactate gluconate, zinc polyflavonoid), ferrous sulphate, copper sulphate, Manganese sulphate, boron (borax-sodium tetraborate, boric acid (H3BO3), di-sodium octa borate tetra hydrate (Na2B8O13.4H2O), di-sodium tetra borate penta hydrate, anhydrous borax, ) and sulphur (elemental sulphur, bentonite sulphur, boronated sulphur or a sulphate and thiosulphate salt) or mixture thereof.
Plant health additives may or may not be in nano particles form.
The present invention provides formulation for the aforesaid composition and method of preparation thereof.
Gibberellic acid
Gibberellic acid (GA3) is a simple gibberellin, a pentacyclic diterpene acid promoting growth and elongation of cells. It affects decomposition of plants and helps plants grow if used in small amounts. Gibberellic acid is a very potent hormone whose natural occurrence in plants controls their development. Since GA3 regulates growth, applications of very low concentrations can have a profound effect on plant development. Gibberellins have a number of effects on plant development. They can stimulate rapid stem and root growth, induce mitotic division in the leaves of some plants, and increase seed germination rates.
Evaluation of regulatory influence of plant growth regulators comprising Gibberellic acid on the reproductive potential and longevity of B. cucurbitae showed a significant adverse influence on the reproductive potential of the pest.
The impact of the plant growth regulator gibberellic acid (GA3) on parasitoid development and reproduction was examined. A prolongation in the immature developmental time after the application of GA3 was reported in S. litura and B. cucurbitae. The growth and developmental inhibitory effects on host species with a considerable decline in larval survival of S. litura and 100% mortality in B. cucurbitae was reported.
The advantages of granular agrochemical composition comprising Gibberellic acid are as follows:
(a) Increase in yield of treated plants (cereals, pulses, oilseeds, fiber crop, sugar crops, leafy vegetables, tuber crops, fruit crops, flowers, ornamentals etc.),
(b) Increase in yield due to protection against insect-pests, fungal diseases and plant parasitic nematodes,
(c) Increase in yield due to plant growth regulation by modified vegetative and reproductive growth of crops/plants,
(d) Increase in yield due to more number of tillers, more branches and sub branches, more number of flowers, more number of fruits,
(e) Increases plant vigor,
(f) Increases tolerance to insect-pests damage,
(g) Increases tolerance to the weather stress, moisture stress,
(h) Prevents lodging in susceptible plants (lodging due to biotic and abiotic factors, like heavy rains, winds, insects and diseases damage,
(i) Improves quality (means visual appearance, color, size, shape etc.) in grains, fruits, fiber, flowers, tuber, bulb, rhizomes, straw, leaves and other plant parts and plant products,
(j) Improves keeping quality of produce, increase post harvest life, storage life, protection from post harvest diseases and
(k) Uniform sizing in tuber, bulb, rhizome and root crops.
The granular agrochemical compositions are used to increase the yield and to protect the crops and plants from insect and pests. The lists of the major crops includes but are not limited to GMO (Genetically Modified Organism) and Non GMO varieties of Cotton (Gossypium spp.), Paddy (Oryza sativa), Wheat (Triticum aestavum), Barley (Hordeum vulgare), Maize (Zea mays), Sorghum (Sorghum bicolor), Oat (Avena sativa), Pearl millet (Pennisetum glaucum), Sugarcane (Saccharum officinarum) , Sugarbeet (Beta vulgaris), Soybean (Glycin max), Peanut (Arachis hypogaea), Sunflower (Helianthus annuus) , Mustard (Brassica juncea), Rape seed (Brassica napus), Linseed (Linum usitatissimum), Sesame (Sesamum indicum), Green gram (Vigna radiata), Black gram (Vigna mungo), Chickpea (Cicer aritinum), Cowpea (Vigna unguiculata), Redgram (Cajanus cajan), Frenchbean (Phaseolus vulgaris), Indian bean (Lablab purpureus), Horse gram (Macrotyloma uniflorum), Field pea (Pisum sativum), Cluster bean (Cyamopsis tetragonoloba), Lentils (Lens culinaris), Brinjal (Solanum melongena), Cabbage (Brassica oleracea var. capitata), Cauliflower (Brassica oleracea var. botrytis), Okra (Abelmoschus esculentus) , Onion (Allium cepa L.), Tomato (Solanum lycopersicun) , Potato (Solanum tuberosum) , Sweet potato (Ipomoea batatas), Chilly (Capsicum annum), Garlic (Allium sativum), Cucumber (Cucumis sativus), Muskmelons (Cucumis melo), Watermelon (Citrullus lanatus), Bottle gourd (Lagenaria siceraria), Bitter gourd (Momordica charantia), Radish (Raphanus sativus), Carrot (Dacus carota subsp. sativus), Turnip (Brassica rapa subsp rapa), Apple (Melus domestica), Banana (Musa spp.), Citrus groups (Citrus spp.), Grape (Vitis vinifera), Guava (Psidium guajava), Litchi (Litchi chinensis), Mango (Mangifera indica), Papaya (Carica papaya), Pineapple (Ananas comosus), Pomegranate (Punica granatum) , Sapota (Manilkara zapota), Tea (Camellia sinensis), Coffea (Coffea Arabica), Turmeric (Curcuma longa), Ginger (Zingiber officinale), Cumin (Cuminum cyminum), Fenugreek (Trigonella foenum-graecum), Fennel (Foeniculum vulgare), Coriander (Coriandrum sativum), Ajwain (Trachyspermum ammi), Psyllium (Plantago ovate), Black Pepper (Piper nigrum), Stevia (Stevia rebaudiana), Safed musli (Chlorophytum tuberosum), Drum stick (Moringa oleifera), Coconut (Coco nucifera), Mentha ( Mentha spp.), Rose (Rosa spp.), Jasmine (Jasminum spp.), Marigold ( Tagetes spp.), Common daisy (Bellis perennis), Dahlia (Dahlia hortnesis), Gerbera ( Gerbera jamesonii), Carnation (Dianthus caryophyllus), vegetables: solanaceous vegetables such as eggplant, tomato, pimento, pepper, potato, etc., cucurbit vegetables such as cucumber, pumpkin, zucchini, water melon, melon, squash, etc., cruciferous vegetables such as radish, white turnip, horseradish, kohlrabi, Chinese cabbage, cabbage, leaf mustard, broccoli, cauliflower, etc., asteraceous vegetables such as burdock, crown daisy, artichoke, lettuce, etc, liliaceous vegetables such as green onion, onion, garlic, and asparagus, ammiaceous vegetables such as carrot, parsley, celery, parsnip, etc., chenopodiaceous vegetables such as spinach, Swiss chard, etc., lamiaceous vegetables such as Perilla frutescens, mint, basil, etc, strawberry, sweet potato, Dioscorea japonica, colocasia, etc., flowers, foliage plants, turf grasses, fruits: pome fruits such apple, pear, quince, etc, stone fleshy fruits such as peach, plum, nectarine, Prunus mume, cherry fruit, apricot, prune, etc., citrus fruits such as orange, lemon, rime, grapefruit, etc., nuts such as chestnuts, walnuts, hazelnuts, almond, pistachio, cashew nuts, macadamia nuts, etc. berries such as blueberry, cranberry, blackberry, raspberry, etc., grape, kaki fruit, olive, plum, banana, coffee, date palm, coconuts, etc. , trees other than fruit trees; tea, mulberry, flowering plant, trees such as ash, birch, dogwood, Eucalyptus, Ginkgo biloba, lilac, maple, Quercus, poplar, Judas tree, Liquidambar formosana, plane tree, zelkova, Japanese arborvitae, fir wood, hemlock, juniper, Pinus, Picea, and Taxus cuspidate, etc.
The granular agrochemical compositions are used to control the insects-pests and diseases. The major insects pests controlled are belongs to the order Hemiptera, for example, rice leafhopper/green leaf hopper (GLH) Nephotettix nigropictus, rice brown plant hopper (BPH) Nilaparvata lugen, rice backed plant hopper (WBPH) Sogatella furcifera, Apple Mealy bug Phenococcus aceris, bean aphid Aphis fabae, black citrus aphid Toxoptera aurantii, citrus black scale Saissetia oleae, cabbage aphid Brevicoryne brassicae, Lipaphis erysimi, citrus red scale Aonidiella aurantii, yellow scale Aonidiella citrine, citrus mealybug Planococcus citri, corn leaf aphid Rhopalosiphum maidis, aphid Aphis gossypii, jassid Amrasca biguttula biguttla, mealy bug Planococcus spp. And Pseudococcus spp., cotton stainer Dysdercus suturellus, whitefly Bemisia tabaci, cowpea aphid Aphis crassivora, grain aphid Sitobion avenae, golden glow aphid Uroleucon spp., grape mealybug Pseudococcus maritimus, green peach aphid Myzus persicae, greenhouse whitefly Trialeurodes vaporariorum, papaya mealy bug Pracoccus marginatus, pea aphid Acyrthosiphon pisum, sugarcane mealybug Saccharicoccus sacchari, potato aphid Myzus persicae, potato leaf hopper Empoasca fabae, cotton whitefly Bemisia tabaci, tarnished plant bug Lygus lineolaris, wooly apple aphid Eriosoma lanigerum, mango hopper Amritodus atkinsoni, Idioscopus spp. ; order Lepidoptera, army worm Mythimna unipuncta, asiatic rice borer Chilo suppressalis, bean pod borer Maruca vitrata, beet armyworm Spodoptera exigua, black cutworm Agrotis ipsilon, bollworm Helicoverpa armigera , cabbage looper Trichoplusia ni, codling moth Cydia pomonella, croton caterpillar Achea janata, diamond backmoth Plutella xylostella, cabbage worm Pieris rapae, pink bollworm Pectinophora gossypiella, sugarcane borer Diatraea saccharalis, sugarcane early shoot borer Chilo infuscatellus tobacco budworm Heliothis virescens, tomato fruitworm Helicoverpa zea, velvet bean caterpillar Anticarsia gemmatalis, yellow stem borer Scirpophaga incertulas, spotted bollworm Earias vittella, rice leaffolder Cnaphalocrocis medinalis, pink stem borer Sesamia spp., tobacco leafeating caterpillar Spodoptera litura; brinjal fruit and shoot borer Leucinodes orbonalis, bean pod borer Maruca vitrata, Maruca testulalis, armyworm Mythimna separata, cotton pinkbollworm Pectinophora gossypiella, citrus leafminer Phyllocnistis citrella, cabbage butterfly Pieris bras-sicae, diamond backmoth Plutella xylostella, paddy stem borer Scirpophaga excerptallis, Scirpophaga incertulas, Scirpophaga innotata, wheat stem borer Sesamia inferens, Sitotroga cerealella, Spilosoma obliqua, fall armyworm Spodoptera frugiperda, Spodoptera littoralis, Spodoptera litura, Trichoplusia ni, Tryporyza nivella, Tryporyza incertulas, Tuta absoluta.
from the order Coleoptera, for example, apple twig borer Amphicerus spp., corn root worm Diabrotica virgifera, cucumber beetle diabrotica balteata, boll weevil Anthonomus grandis, grape flea beetle Altica chalybea, grape root worm Fidia viticola, grape trunk borer Clytoleptus albofasciatus, radish flea beetle Phyllotreta armoraciae, maize weevil Sitophilus zeamais, northern corn rootworm Diabrotica barberi, rice water weevil Lissorhoptrus oryzophilus, Anthonomus grandis, Bruchus lentis, Diabrotica semipunctata, Diabrotica virgifera, Dicladispa armigera, Epila-chna varivestis, various species of white grubs are Holotrichia bicolor, Holotrichia consanguinea, Holotrichia serrata, Leptinotarsa decemlineata, Phyllotreta chrysocephala, Popillia japonica etc; from the order Orthoptera, for example, Gryllotalpa spp., Locusta spp., and Schistocerca is spp.; from the order Thysanoptera, for example, Thrips- Frankliniella spp., Thrips palmi, Thrips tabaci and Scirtothrips dorsalis; termites (Isoptera), e.g. Calotermes flavicollis, Coptotermes formosanus, Heterotermes aureus, Leucotermes flavipes, Microtermes obesi, Odontotermes obesus, Reticulitermes flavipes, Termes natalensis; from the order Heteroptera, for example, Dysdercus spp., Leptocorisa spp., from the order Hymenoptera, for example, Solenopsis spp. ; from the order Diptera, for example, Antherigona soccata, Dacus spp., Liriomyza spp., Melanagromyza spp., from the order Acarina, for example, Aceria mangiferae, Brevipalpus spp., Eriophyes spp., Oligonychus mangiferus, Oligonychus punicae, Panonychus citri, Panonychus ulmi, Polyphagotarsonemus latus, Tarsonemus spp., Tetranychus urticae, Tetranychus cinnabarinus.
The present invention can be employed for controlling phytopathogenic fungi such as Ascomycetes, Basidiomycetes, Chytridiomycetes, Deuteromycetes, Oomycetes, Plasmodiophoromycetes, Zygomycetes, and the like.
Examples which may be mentioned, but not by limitation, are some pathogens of fungal diseases
Which come under the above generic terms:
Diseases caused by pathogens causing powdery mildew such as, for example, Blumeria species such as, for example, Blumeria graminis; Podosphaera species such as, for example, Podosphaera leucotricha; Oidium species such as, for example Oidium mangiferae, Sphaerotheca species such as, for example, Sphaerotheca fuliginea; Uncinula species such as, for example, Uncinula necator; Leveillula species such as, for example Leveillula taurica, Erysiphe species such as for example Erysiphe polygoni, diseases caused by pathogens of rust diseases such as, for example, Gymnosporangium species such as, for example, Gymnosporangium sabinae, Hemileia species such as, for example, Hemileia vastatrix; Phakopsora species such as, for example, Phakopsora pachyrhizi and Phakopsora meibomiae; Puccinia species such as, for example, Puccinia graminis, Puccinia recondita or Puccinia triticina, Puccinia striiformis; Uromyces species such as, for example, Uromyces phaseoli; diseases caused by pathogens of smut diseases such as, for example, Sporisorium species such as , for example, Sporisorium scitamineum; Ustilago species such as, for example Ustilago maydis, Tilletia species such as for example Tilletia tritici, Ustilaginoidea species such as , for example Ustilaginoidea virens, diseases caused by pathogens of ergot diseases such as, for example Claviceps species, Claviceps purpurea; diseases caused by pathogens from the group of the Oomycetes such as, for example, Bremia species such as, for example, Bremia lactucae; Peronospora species such as, for example, Peronospora pisi or P. brassicae; Phytophthora species such as, for example, Phytophthora infestans; Plasmopara species such as, for example, Plasmopara viticola; Pseudoperonospora species such as, for example, Pseudoperonospora humuli or Pseudoperonospora cubensis; Pythium species such as, for example, Pythium ultimum; leaf spot diseases and leaf wilt caused by, for example, Alternaria species such as, for example, Alternaria solani; Cercospora species such as, for example, Cercospora arachidicola; Cladiosporum species such as, for example, Cladiosporium cucumerinum; Cochliobolus species such as, for example, Cochliobolus sativus (conidial form: Drechslera, syn: Helminthosporium);
Colletotrichum species such as, for example, Colletotrichum lindemuthanium; Cycloconium species such as, for example, Cycloconium oleaginum; Diaporthe species such as, for example, Diaporthe citri;
Elsinoe species such as, for example, Elsinoe fawcettii; Gloeosporium species such as, for example, Gloeosporium laeticolor; Glomerella species such as, for example, Glomerella cingulata; Guignardia species such as, for example, Guignardia bidwelli; Leptosphaeria species such as, for example, Leptosphaeria maculans; Magnaporthe species such as, for example, Magnaporthe grisea;
Mycosphaerella species such as, for example, Mycosphaerella graminicola; Phaeosphaeria species such as, for example, Phaeosphaeria nodorum; Pyrenophora species such as, for example, Pyrenophora teres;
Ramularia species such as, for example, Ramularia collo-cygni; Rhynchosporium species such as, for example, Rhynchosporium secalis; Septoria species such as, for example, Septoria apii;
Typhula species such as, for example, Typhula incarnata; Venturia species such as, for example, Venturia inaequalis; root and stalk diseases, caused by, for example, Corticium species such as, for example, Corticium graminearum; Fusarium species such as, for example, Fusarium oxysporum;
Gaeumannomyces species such as, for example, Gaeumannomyces graminis; Rhizoctonia species such as, for example, Rhizoctonia solani; Tapesia species such as, for example, Tapesia acuformis;
Thielaviopsis species such as, for example, Thielaviopsis basicola; ear and panicle diseases (including maize cobs), caused by, for example, Alternaria species such as, for example, Alternaria spp.;
Aspergillus species such as, for example, Aspergillus flavus; Cladosporium species such as, for example, Cladosporium spp.; Claviceps species such as, for example, Claviceps purpurea;
Fusarium species such as, for example, Fusarium culmorum; Gibberella species such as, for example, Gibberella zeae; Monographella species such as, for example, Monographella nivalis;
diseases caused by smuts such as, for example, Sphacelotheca species such as, for example, Sphacelotheca reiliana; Tilletia species such as, for example, Tilletia caries; Urocystis species such as, for example, Urocystis occulta; Ustilago species such as, for example, Ustilago nuda;
fruit rot caused by, for example, Aspergillus species such as, for example, Aspergillus flavus;
Botrytis species such as, for example, Botrytis cinerea; Penicillium species such as, for example, Penicillium expansum; Sclerotinia species such as, for example, Sclerotinia sclerotiorum;
Verticilium species such as, for example, Verticilium alboatrum; seed- and soil-borne rots and wilts, and seedling diseases, caused by, for example, Fusarium species such as, for example, Fusarium culmorum; Phytophthora species such as, for example, Phytophthora cactorum; Pythium species such as, for example, Pythium ultimum; Rhizoctonia species such as, for example, Rhizoctonia solani;
Sclerotium species such as, for example, Sclerotium rolfsii; cankers, galls and witches' broom diseases, caused by, for example, Nectria species such as, for example, Nectria galligena; wilts caused by, for example, Monilinia species such as, for example, Monilinia laxa; deformations of leaves, flowers and fruits, caused by, for example, Taphrina species such as, for example, Taphrina deformans; degenerative diseases of woody species, caused by, for example, Esca species such as, for example, Phaemoniella clamydospora; flower and seed diseases, caused by, for example, Botrytis species such as, for example, Botrytis cinerea; diseases of plant tubers caused by, for example, Rhizoctonia species such as, for example, Rhizoctonia solani; diseases caused by bacterial pathogens such as, for example, Xanthomonas species such as, for example, Xanthomonas campestris pv. oryzae; Pseudomonas species such as, for example, Pseudomonas syringae pv. lachrymans; Erwinia species such as, for example, Erwinia amylovora.
The term "health of a plant" or "plant health" is defined as a condition of the plant and/or its products. As a result of the improved health, yield, plant vigor, quality and tolerance to abiotic or biotic stress are increased. Noteworthy, the health of a plant when applying the method according to the invention, is increased independently of the pesticidal properties of the active ingredients used because the increase in health is not based upon the reduced pest pressure but instead on complex physiological and metabolic reactions which result for example in an activation of the plant's own natural defense system. As a result, the health of a plant is increased even in the absence of pest pressure. Accordingly, in an especially preferred embodiment of the method according to the invention, the health of a plant is increased both in the presence and absence of biotic or abiotic stress factors. The above identified indicators for the health condition of a plant may be interdependent or they may result from each other. An increase in plant vigor may for example result in an increased yield and/or tolerance to abiotic or biotic stress. One indicator for the condition of the plant is the yield. "Yield" is to be understood as any plant product of economic value that is produced by the plant such as grains, fruits in the proper sense, vegetables, nuts, grains, seeds, wood (e.g. in the case of silviculture plants) or even flowers (e.g. in the case of gardening plants, ornamentals). The plant products may in addition be further utilized and/or processed after harvesting.
In an especially preferred embodiment of the invention, the yield of the treated plant is increased.

In another preferred embodiment of the invention, the yield of the plants treated according to the method of the invention, is increased synergistically.

According to the present invention, "increased yield" of a plant, in particular of an agricultural, silvicultural and/or horticultural plant means that the yield of a product of the respective plant is increased by a measurable amount over the yield of the same product of the plant produced under the same conditions, but without the application of the mixture according to the invention.

Increased yield can be characterized, among others, by the following improved proper-ties of the plant: increased plant, weight, increased plant height, increased biomass such as higher overall fresh weight (FW), increased number of flowers per plant, higher grain yield, more tillers or side shoots (branches), larger leaves, increased shoot growth, increased protein content, increased oil content, increased starch content, increased pigment content, increased leaf are index.

According to the present invention, the yield is increased by at least 5%, preferable by 5 to 10 %, more preferable by 10 to 20 %, or even 20 to 30 % compared to the untreated control plants or plants treated with pesticides in a way different from the method according to the present invention. In general, the yield increase may even be higher.

A further indicator for the condition of the plant is the plant vigor. The plant vigor becomes manifest in several aspects such as the general visual appearance. In another especially preferred embodiment of the invention, the plant vigor of the treated plant is increased. In another preferred embodiment of the invention, the plant vigor of the plants treated according to the method of the invention, is increased synergistically. Improved plant vigor can be characterized, among others, by the following improved properties of the plant: improved vitality of the plant, improved plant growth, improved plant development, improved visual appearance, improved plant stand (less plant verse/lodging), improved emergence, enhanced root growth and/or more developed root system, enhanced nodulation, in particular rhizobial nodulation, bigger leaf blade, bigger size, increased plant weight, increased plant height, increased tiller number, increased number of side shoots, increased number of flowers per plant, increased shoot growth, increased root growth (extensive root system), increased yield when grown on poor soils or unfavorable climate, enhanced photosynthetic activity (e.g. based on increased stomatal conductance and/or increased CO2 assimilation rate), increased stomatal conductance, increased CO2 assimilation rate, enhanced pigment content (e.g. chlorophyll content), earlier flowering, earlier fruiting, earlier and improved germination, earlier grain maturity, improved self-defense mechanisms, improved stress tolerance and resistance of the plants against biotic and abiotic stress factors such as fungi, bacteria, viruses, insects, heat stress, cold stress, drought stress, UV stress and/or salt stress, less non-productive tillers, less dead basal leaves, less input needed (such as fertilizers or water), greener leaves, complete maturation under shortened vegetation periods, less fertilizers needed, less seeds needed, easier harvesting, faster and more uniform ripening, longer shelf-life, longer panicles, delay of senescence, stronger and/or more productive tillers, better extractability of ingredients, improved quality of seeds (for being seeded in the following seasons for seed production), better nitrogen uptake, improved reproduction, reduced production of ethylene and/or the inhibition of its reception by the plant.

The improvement of the plant vigor according to the present invention particularly means that the improvement of any one or several or all of the above mentioned plant characteristics are improved independently of the pesticidal action of the mixture or active ingredients (components).

Another indicator for the condition of the plant is the "quality" of a plant and/or its products.

In an especially preferred embodiment of the invention, the quality of the treated plant is increased.
In another preferred embodiment of the invention, the quality of the plants treated according to the method of the invention, is increased synergistically.

According to the present invention, enhanced quality means that certain plant characteristics such as the content or composition of certain ingredients are increased or improved by a measurable or noticeable amount over the same factor of the plant produced under the same conditions, but without the application of the mixtures of the present invention. Enhanced quality can be characterized, among others, by following improved properties of the plant or its product: increased nutrient content, increased protein content, increased content of fatty acids, increased metabolite content, increased carotenoid content, increased sugar content, increased amount of essential amino acids, improved nutrient composition, improved protein composition, improved composition of fatty acids, improved metabolite composition, improved carotenoid composition, improved sugar composition, improved amino acids composition, improved or optimal fruit color, improved leaf color, higher storage capacity, higher processability of the harvested products.

Another indicator for the condition of the plant is the plant's tolerance or resistance to biotic and/or abiotic stress factors. Biotic and abiotic stress, especially over longer terms, can have harmful effects on plants. Biotic stress is caused by living organisms while abiotic stress is caused for example by environmental extremes. According to the present invention, "enhanced tolerance or resistance to biotic and/or abiotic stress factors" means (1.) that certain negative factors caused by biotic and/or abiotic stress are diminished in a measurable or noticeable amount as compared to plants exposed to the same conditions, but without being treated with a mixture according to the invention and (2.) that the negative effects are not diminished by a direct action of the mixture according to the invention on the stress factors, e.g. by its fungicidal or insecticidal action which directly destroys the microorganisms or pests, but rather by a stimulation of the plants' own defensive reactions against said stress factors.

Formulation of the present invention can be in any of the formulations selected from Granule (GR), Soil Applied Granules (SAG), Controlled release granules (CR) may be slow release granule or fast release granules.
Further composition comprising (A) gibberellic acid; and (B) one or more of active ingredients selected from class of an insecticide; class of fungicides; or a plant health additive; or combination thereof are present in the said composition in specific fixed ratio.
In further aspect the present invention relates to the granular pesticidal composition comprising bioactive amounts of (A) is 0.001 to 10% w/w of the composition; and (B) is 0.01 to 90 % w/w of the composition.
Active Ingredients Compound A Compound B
Examples gibberellic acid one or more of active ingredients selected from class of an insecticide; class of fungicides; or a plant health additive
% of Active Ingredient 0.001 to 10% 0.01 to 90%
The granular agrochemical composition of the present invention in addition to bioactive amounts of active ingredients further comprises inactive excipients including but not limited to wetting agent, dispersing agent, solvent, carrier, colouring agent and controlled release agent.
The process for preparing the present Granular agrochemical composition comprising Gibberellic acid for promoting plant health can be modified accordingly by any person skilled in the art based on the knowledge of the manufacturing the formulation. However all such variation and modification is still covered by the scope of present invention.
Lists of preferred granular composition containing Gibberellic acid
Compound A Compound B Active ingredients (%) Formulation Strength (%)
Compound A Compound B
GA Zinc 0.1 12 12.10
GA Sulphur 0.1 90 90.10
GA Humic acid (Potassium humate) 0.1 10 10.10
GA Fulvic acid (Potassium fulvate) 0.1 10 10.10
GA Amino acid (glycine) 0.1 10 10.10
GA Seaweed extract (extract of ascophyllum nodasum) 0.1 10 10.10
GA Chitosan 0.1 10 10.10
GA Ortho silicic acid 0.1 10 10.10
GA Brassinolide 0.02 0.04 0.06
GA Salicylic acid 0.02 2 2.02
GA Triacontanol 0.05 0.2 0.25
GA Paclobutrazol 0.1 0.3 0.40
GA Prohexadione calcium 0.1 0.5 0.60
GA Trinexapac ethyl 0.1 0.5 0.60
GA Chlormequat chloride 0.1 0.5 0.60
GA Uniconazole-P 0.1 1 1.10
GA Carbofuran 0.05 10 10.05
GA Chlorpyrifos 0.05 10 10.05
GA Fipronil 0.05 0.75 0.80
GA Bifenthrin 0.05 1 1.05
GA Clothianidin 0.15 0.75 0.90
GA Thiamethoxam 0.15 0.75 0.90
GA Imidacloprid 0.15 0.75 0.90
GA Thiamethoxam 0.15 0.75 0.90
GA Flupyrimin 0.15 1 1.15
GA Triflumezopyrim 0.15 0.5 0.65
GA Spinetoram 0.05 0.5 0.55
GA Abamectin 0.05 0.2 0.25
GA Emamectin benzoate 0.05 0.2 0.25
GA Pymetrozine 0.05 2 2.05
GA Bensultap 0.1 5 5.10
GA Monosultap 0.1 5 5.10
GA Cartap hydrochloride 0.1 5 5.10
GA Thiocyclam hydrogen oxalate 0.1 5 5.10
GA Buprofezin 0.05 2 2.05
GA Chlorantraniliprole 2.32 35 37.32
GA Cyantraniliprole 1.17 35 36.17
GA Cyclaniliprole 0.5 0.5 1.00
GA Tetraniliprole 1.4 35 36.40
GA Tetrachlorantraniliprole 0.1 0.5 0.60
GA Cyhalodiamide 0.1 0.5 0.60
GA Flubendiamide 0.1 0.7 0.80
GA Broflanilide 2 20 22.00
GA Flonicamid 1 50 51.00
GA Azoxystrobin 0.02 2.5 2.52
GA Pyraclostrobin 0.02 2.5 2.52
GA Picoxystrobin 0.02 2.5 2.52
GA Trifloxystrobin 0.02 2.5 2.52
GA Kresoxim methyl 0.02 2.5 2.52
GA Tebuconazole 0.02 2 2.02
GA Hexaconazole 0.02 2 2.02
GA Triticonazole 0.02 2 2.02
GA Propiconazole 0.02 2 2.02
GA Difenoconazole 0.02 2 2.02
GA Prothioconazole 0.02 2 2.02
GA Epoxyconazole 0.02 2 2.02
GA Cyproconazole 0.02 2 2.02
GA Carbendazim 0.02 2.5 2.52
GA Thiophanate methyl 0.02 2.5 2.52
GA Carboxin 0.02 2.5 2.52
GA Metalaxyl 0.02 2.5 2.52
GA Metalaxyl-M 0.02 2.5 2.52
GA Fludioxanil 0.02 2.5 2.52
GA Thifluzamide 0.02 2 2.02
GA Benzovindiflupyr 0.02 2 2.02
GA Bixafen 0.02 2 2.02
GA Fluindapyr 0.02 2 2.02
GA Fluxapyroxad 0.02 2 2.02
GA Furametpyra 0.02 2 2.02
GA Isopyrazam 0.02 2 2.02
GA Penflufen 0.02 2 2.02
GA Penthiopyrad 0.02 2 2.02
GA Sedaxane 0.02 2 2.02
GA Flubeneteram 0.02 2 2.02
GA Pyrapropoyne 0.02 2 2.02
GA Inpyrfluxam 0.02 2 2.02
GA Isoflupyram 0.02 2 2.02
GA Pydiflumetofen 0.02 2 2.02
GA Boscalid 0.02 2 2.02
GA Pyraziflumid 0.02 2 2.02
GA Copper 0.02 5 5.02
GA Mancozeb 0.02 5 5.02
GA Chlorothalonil 0.02 5 5.02
GA Metiram 0.02 5 5.02

GA-Gibberellic acid
Compound A Compound B Active ingredients (%) Formulation Strength (%)
B1 B2 Compound A Compound
B1 B2
GA Zinc Sulphur 0.1 12 60 72.10
GA Zinc Triacontanol 0.1 12 0.1 12.20
GA Zinc Sulphur 0.1 20 60 80.10
GA Zinc Triacontanol 0.1 20 0.1 20.20
GA Zinc Chlorantraniliprole 2 10 30 42.00
GA Zinc Cyantraniliprole 1 5 30 36.00
GA Zinc Tetraniliprole 1 5 20 26.00
GA Zinc Cyclaniliprole 1 5 20 26.00
GA Zinc Broflanilide 4 20 20 44.00
GA Zinc Flubendiamide 1 5 20 26.00
GA Zinc Cartap 0.0670 1.33 5 6.40
GA Zinc THO 0.0670 1.33 3.33 4.73
GA Sulphur Chlorantraniliprole 0.1 60 0.4 60.50
GA Sulphur Cyantraniliprole 0.1 60 0.6 60.70
GA Sulphur Tetraniliprole 0.1 60 0.5 60.60
GA Sulphur Flubendiamide 0.1 60 0.7 60.80
GA Sulphur Cyclaniliprole 0.1 60 0.5 60.60
GA Sulphur Cartap 0.067 40 5.0 45.07
GA Sulphur THO 0.067 40 3.33 43.40
GA Zinc Clothianidin 0.05 2 0.75 2.80
GA Zinc Thiamethoxam 0.05 2 0.75 2.80
GA Zinc Fipronil 0.05 2 0.75 2.80
GA Zinc Cartap 0.05 2 5 7.05
GA Zinc THO 0.05 2 5 7.05
GA Zinc Flupyrimin 0.05 2 2 4.05
GA Zinc Triflumezopyrim 0.05 2 0.25 2.30
GA Zinc Pymetrozine 0.05 2 2 4.05
GA Triacontanol Clothianidin 0.05 0.125 0.75 0.93
GA Triacontanol Thiamethoxam 0.05 0.125 0.75 0.93
GA Triacontanol Fipronil 0.05 0.125 0.75 0.93
GA Triacontanol Cartap 0.05 0.125 5 5.18
GA Triacontanol THO 0.05 0.125 5 5.18
GA Triacontanol Flupyrimin 0.05 0.125 2 2.18
GA Triacontanol Triflumezopyrim 0.05 0.125 0.25 0.43
GA Triacontanol Pymetrozine 0.05 0.125 2 2.18
GA Triacontanol Chlorantraniliprole 0.05 0.125 0.4 0.58
GA Triacontanol Cyantraniliprole 0.05 0.125 0.6 0.78
GA Triacontanol Tetraniliprole 0.05 0.125 0.6 0.78
GA Triacontanol Flubendiamide 0.05 0.125 0.7 0.88
GA Fipronil Clothianidin 0.08 0.6 0.75 1.43
GA Fipronil Thiamethoxam 0.08 0.6 1 1.68
GA Fipronil Imidacloprid 0.08 0.6 0.75 1.43
GA Fipronil Bifenthrin 0.08 0.6 0.75 1.43
GA Clothianidin Bifenthrin 0.025 1 0.75 1.78
GA Thiamethoxam Bifenthrin 0.025 1 0.75 1.78
GA Imidacloprid Bifenthrin 0.025 1 0.75 1.78
GA Flonicamid Fipronil 0.3 12 12 24.30
GA Flonicamid Tolfenpyrad 0.3 12 15 27.30
GA Flonicamid Diafenthiuron 0.15 6 20 26.15
GA Flonicamid Profenofos 0.15 6 25 31.15
GA Flonicamid Abamectin 0.75 30 3.75 34.50
GA Humic acid Chlorantraniliprole 0.05 2.5 0.4 2.95
GA Humic acid Cyantraniliprole 0.05 2.5 0.5 3.05
GA Humic acid Tetraniliprole 0.05 2.5 0.5 3.05
GA Humic acid Clothianidin 0.05 2.5 0.75 3.30
GA Humic acid Thiamethoxam 0.05 2.5 0.75 3.30
GA Humic acid Fipronil 0.05 2.5 0.75 3.30
GA Humic acid Cartap 0.05 2.5 4 6.55
GA Humic acid THO 0.05 2.5 4 6.55
GA Humic acid Flupyrimin 0.05 2.5 1 3.55
GA Humic acid Triflumezopyrim 0.05 2.5 0.5 3.05
GA Humic acid Pymetrozine 0.05 2.5 2 4.55
GA Chitosan Chlorantraniliprole 0.05 2.5 0.4 2.95
GA Chitosan Cyantraniliprole 0.05 2.5 0.5 3.05
GA Chitosan Tetraniliprole 0.05 2.5 0.5 3.05
GA Chitosan Clothianidin 0.05 2.5 0.75 3.30
GA Chitosan Thiamethoxam 0.05 2.5 0.75 3.30
GA Chitosan Fipronil 0.05 2.5 0.75 3.30
GA Chitosan Cartap 0.05 2.5 4 6.55
GA Chitosan THO 0.05 2.5 4 6.55
GA Chitosan Flupyrimin 0.05 2.5 1 3.55
GA Chitosan Triflumezopyrim 0.05 2.5 0.5 3.05
GA Chitosan Pymetrozine 0.05 2.5 2 4.55
GA Brassinolide Chlorantraniliprole 0.05 0.02 0.4 0.47
GA Brassinolide Cyantraniliprole 0.05 0.02 0.5 0.57
GA Brassinolide Tetraniliprole 0.05 0.02 0.5 0.57
GA Brassinolide Clothianidin 0.05 0.02 0.75 0.82
GA Brassinolide Thiamethoxam 0.05 0.02 0.75 0.82
GA Brassinolide Fipronil 0.05 0.02 0.75 0.82
GA Brassinolide Cartap 0.05 0.02 4 4.07
GA Brassinolide THO 0.05 0.02 4 4.07
GA Brassinolide Flupyrimin 0.05 0.02 1 1.07
GA Brassinolide Triflumezopyrim 0.05 0.02 0.5 0.57
GA Brassinolide Pymetrozine 0.05 0.02 2 2.07
GA Seaweed extract Chlorantraniliprole 0.05 2.5 0.4 2.95
GA Seaweed extract Cyantraniliprole 0.05 2.5 0.5 3.05
GA Seaweed extract Tetraniliprole 0.05 2.5 0.5 3.05
GA Seaweed extract Clothianidin 0.05 2.5 0.75 3.30
GA Seaweed extract Thiamethoxam 0.05 2.5 0.75 3.30
GA Seaweed extract Fipronil 0.05 2.5 0.75 3.30
GA Seaweed extract Cartap 0.05 2.5 4 6.55
GA Seaweed extract THO 0.05 2.5 4 6.55
GA Seaweed extract Flupyrimin 0.05 2.5 1 3.55
GA Seaweed extract Triflumezopyrim 0.05 2.5 0.5 3.05
GA Seaweed extract Pymetrozine 0.05 2.5 2 4.55
GA Paclobutrazol Chlorantraniliprole 0.05 0.25 0.4 0.70
GA Paclobutrazol Cyantraniliprole 0.05 0.25 0.5 0.80
GA Paclobutrazol Tetraniliprole 0.05 0.25 0.5 0.80
GA Paclobutrazol Clothianidin 0.05 0.25 0.75 1.05
GA Paclobutrazol Thiamethoxam 0.05 0.25 0.75 1.05
GA Paclobutrazol Fipronil 0.05 0.25 0.75 1.05
GA Paclobutrazol Cartap 0.05 0.25 4 4.30
GA Paclobutrazol THO 0.05 0.25 4 4.30
GA Paclobutrazol Flupyrimin 0.05 0.25 1 1.30
GA Paclobutrazol Triflumezopyrim 0.05 0.25 0.5 0.80
GA Paclobutrazol Pymetrozine 0.05 0.25 2 2.30
GA Triacontanol Chlorantraniliprole 0.05 0.2 0.4 0.65
GA Triacontanol Cyantraniliprole 0.05 0.2 0.5 0.75
GA Triacontanol Tetraniliprole 0.05 0.2 0.5 0.75
GA Triacontanol Clothianidin 0.05 0.2 0.75 1.00
GA Triacontanol Thiamethoxam 0.05 0.2 0.75 1.00
GA Triacontanol Fipronil 0.05 0.2 0.75 1.00
GA Triacontanol Cartap 0.05 0.2 4 4.25
GA Triacontanol THO 0.05 0.2 4 4.25
GA Triacontanol Flupyrimin 0.05 0.2 1 1.25
GA Triacontanol Triflumezopyrim 0.05 0.2 0.5 0.75
GA Triacontanol Pymetrozine 0.05 0.2 2 2.25
GA Zinc Azoxystrobin 0.05 2 2 4.05
GA Sulphur Azoxystrobin 0.05 20 2 22.05
GA Humic acid Azoxystrobin 0.05 2.5 2 4.55
GA Fulvic acid Azoxystrobin 0.05 2.5 2 4.55
GA Amino acid Azoxystrobin 0.05 2.5 2 4.55
GA Seaweed extract Azoxystrobin 0.05 2.5 2 4.55
GA Chitosan Azoxystrobin 0.05 2.5 2 4.55
GA Ortho silicic acid Azoxystrobin 0.05 2.5 2 4.55
GA Brassinolide Azoxystrobin 0.05 0.02 2 2.07
GA Salicylic acid Azoxystrobin 0.05 2.5 2 4.55
GA Triacontanol Azoxystrobin 0.05 0.2 2 2.25
GA Paclobutrazol Azoxystrobin 0.05 0.4 2 2.45
GA Prohexadione calcium Azoxystrobin 0.05 0.4 2 2.45
GA Trinexapac ethyl Azoxystrobin 0.05 0.4 2 2.45
GA Chlormequat chloride Azoxystrobin 0.05 0.4 2 2.45
GA Uniconazole-P Azoxystrobin 0.05 0.4 2 2.45
GA Zinc Pyraclostrobin 0.05 2 2 4.05
GA Sulphur Pyraclostrobin 0.05 20 2 22.05
GA Humic acid Pyraclostrobin 0.05 2.5 2 4.55
GA Fulvic acid Pyraclostrobin 0.05 2.5 2 4.55
GA Amino acid Pyraclostrobin 0.05 2.5 2 4.55
GA Seaweed extract Pyraclostrobin 0.05 2.5 2 4.55
GA Chitosan Pyraclostrobin 0.05 2.5 2 4.55
GA Ortho silicic acid Pyraclostrobin 0.05 2.5 2 4.55
GA Brassinolide Pyraclostrobin 0.05 0.02 2 2.07
GA Salicylic acid Pyraclostrobin 0.05 2.5 2 4.55
GA Triacontanol Pyraclostrobin 0.05 0.2 2 2.25
GA Paclobutrazol Pyraclostrobin 0.05 0.4 2 2.45
GA Prohexadione calcium Pyraclostrobin 0.05 0.4 2 2.45
GA Trinexapac ethyl Pyraclostrobin 0.05 0.4 2 2.45
GA Chlormequat chloride Pyraclostrobin 0.05 0.4 2 2.45
GA Uniconazole-P Pyraclostrobin 0.05 0.4 2 2.45
GA Zinc Tebuconazole 0.05 2 3 5.05
GA Sulphur Tebuconazole 0.05 20 3 23.05
GA Humic acid Tebuconazole 0.05 2.5 3 5.55
GA Fulvic acid Tebuconazole 0.05 2.5 3 5.55
GA Amino acid Tebuconazole 0.05 2.5 3 5.55
GA Seaweed extract Tebuconazole 0.05 2.5 3 5.55
GA Chitosan Tebuconazole 0.05 2.5 3 5.55
GA Ortho silicic acid Tebuconazole 0.05 2.5 3 5.55
GA Brassinolide Tebuconazole 0.05 0.02 3 3.07
GA Salicylic acid Tebuconazole 0.05 2.5 3 5.55
GA Triacontanol Tebuconazole 0.05 0.2 3 3.25
GA Paclobutrazol Tebuconazole 0.05 0.4 3 3.45
GA Prohexadione calcium Tebuconazole 0.05 0.4 3 3.45
GA Trinexapac ethyl Tebuconazole 0.05 0.4 3 3.45
GA Chlormequat chloride Tebuconazole 0.05 0.4 3 3.45
GA Uniconazole-P Tebuconazole 0.05 0.4 3 3.45
GA Zinc Hexaconazole 0.05 2 1 3.05
GA Sulphur Hexaconazole 0.05 20 1 21.05
GA Humic acid Hexaconazole 0.05 2.5 1 3.55
GA Fulvic acid Hexaconazole 0.05 2.5 1 3.55
GA Amino acid Hexaconazole 0.05 2.5 1 3.55
GA Seaweed extract Hexaconazole 0.05 2.5 1 3.55
GA Chitosan Hexaconazole 0.05 2.5 1 3.55
GA Ortho silicic acid Hexaconazole 0.05 2.5 1 3.55
GA Brassinolide Hexaconazole 0.05 0.02 1 1.07
GA Salicylic acid Hexaconazole 0.05 2.5 1 3.55
GA Triacontanol Hexaconazole 0.05 0.2 1 1.25
GA Paclobutrazol Hexaconazole 0.05 0.4 1 1.45
GA Prohexadione calcium Hexaconazole 0.05 0.4 1 1.45
GA Trinexapac ethyl Hexaconazole 0.05 0.4 1 1.45
GA Chlormequat chloride Hexaconazole 0.05 0.4 1 1.45
GA Uniconazole-P Hexaconazole 0.05 0.4 1 1.45
GA Zinc Thifluzamide 0.05 2 2.5 4.55
GA Sulphur Thifluzamide 0.05 20 2.5 22.55
GA Humic acid Thifluzamide 0.05 2.5 2.5 5.05
GA Fulvic acid Thifluzamide 0.05 2.5 2.5 5.05
GA Amino acid Thifluzamide 0.05 2.5 2.5 5.05
GA Seaweed extract Thifluzamide 0.05 2.5 2.5 5.05
GA Chitosan Thifluzamide 0.05 2.5 2.5 5.05
GA Ortho silicic acid Thifluzamide 0.05 2.5 2.5 5.05
GA Brassinolide Thifluzamide 0.05 0.02 2.5 2.57
GA Salicylic acid Thifluzamide 0.05 2.5 2.5 5.05
GA Triacontanol Thifluzamide 0.05 0.2 2.5 2.75
GA Paclobutrazol Thifluzamide 0.05 0.4 2.5 2.95
GA Prohexadione calcium Thifluzamide 0.05 0.4 2.5 2.95
GA Trinexapac ethyl Thifluzamide 0.05 0.4 2.5 2.95
GA Chlormequat chloride Thifluzamide 0.05 0.4 2.5 2.95
GA Uniconazole-P Thifluzamide 0.05 0.4 2.5 2.95
GA Zinc Thiophanate methyl 0.05 2 2.5 4.55
GA Sulphur Thiophanate methyl 0.05 20 2.5 22.55
GA Humic acid Thiophanate methyl 0.05 2.5 2.5 5.05
GA Fulvic acid Thiophanate methyl 0.05 2.5 2.5 5.05
GA Amino acid Thiophanate methyl 0.05 2.5 2.5 5.05
GA Seaweed extract Thiophanate methyl 0.05 2.5 2.5 5.05
GA Chitosan Thiophanate methyl 0.05 2.5 2.5 5.05
GA Ortho silicic acid Thiophanate methyl 0.05 2.5 2.5 5.05
GA Brassinolide Thiophanate methyl 0.05 0.02 2.5 2.57
GA Salicylic acid Thiophanate methyl 0.05 2.5 2.5 5.05
GA Triacontanol Thiophanate methyl 0.05 0.2 2.5 2.75
GA Paclobutrazol Thiophanate methyl 0.05 0.4 2.5 2.95
GA Prohexadione calcium Thiophanate methyl 0.05 0.4 2.5 2.95
GA Trinexapac ethyl Thiophanate methyl 0.05 0.4 2.5 2.95
GA Chlormequat chloride Thiophanate methyl 0.05 0.4 2.5 2.95
GA Uniconazole-P Thiophanate methyl 0.05 0.4 2.5 2.95
GA Paclobutrazol Sulphur 0.05 0.3 20 20.35
GA Paclobutrazol Sulphur 0.05 0.3 20 20.35
GA Paclobutrazol Sulphur 0.05 0.3 20 20.35
GA Paclobutrazol Sulphur 0.05 0.3 20 20.35
GA Paclobutrazol Zinc 0.05 0.3 2.5 2.85
GA Paclobutrazol Zinc 0.05 0.3 2.5 2.85
GA Paclobutrazol Zinc 0.05 0.3 2.5 2.85
GA Paclobutrazol Zinc 0.05 0.3 2.5 2.85

GA-Gibberellic acid, Cartap-Cartap hydrochloride, THO-Thiocyclam hydrogen oxalate
Compound A Compound B active ingredients(%) Formulation Strength (%)
B1 B2 B3 Compound A Compound B
B1 B2 B3
GA Zinc Sulphur Chlorantraniliprole 0.05 10 50 0.4 60.45
GA Zinc Sulphur Cyantraniliprole 0.05 10 50 0.6 60.65
GA Zinc Sulphur Tetraniliprole 0.05 10 50 0.6 60.65
GA Zinc Sulphur Flubendiamide 0.05 10 50 0.7 60.75
GA Zinc Sulphur Cyclaniliprole 0.05 10 50 0.6 60.65
GA Zinc Sulphur Cartap 0.05 2 50 5 57.05
GA Zinc Sulphur THO 0.05 2 50 5 57.05
GA Zinc Sulphur Flupyrimin 0.05 2 50 2 54.05
GA Zinc Sulphur Triflumezopyrim 0.05 2 50 0.25 52.30
GA Zinc Triacontanol Chlorantraniliprole 0.1 2 0.1 0.4 2.60
GA Zinc Triacontanol Cyantraniliprole 0.1 2 0.1 0.6 2.80
GA Zinc Triacontanol Tetraniliprole 0.1 2 0.1 0.6 2.80
GA Zinc Triacontanol Flubendiamide 0.1 2 0.1 0.7 2.90
GA Zinc Triacontanol Cyclaniliprole 0.1 2 0.1 0.6 2.80
GA Zinc Triacontanol Cartap 0.05 2 0.1 5 7.15
GA Zinc Triacontanol THO 0.05 2 0.1 5 7.15
GA Zinc Triacontanol Flupyrimin 0.05 2 0.1 2 4.15
GA Zinc Triacontanol Triflumezopyrim 0.05 2 0.1 0.25 2.40
GA Zinc Sulphur Clothianidin 0.05 12 60 0.75 72.80
GA Zinc Sulphur Thiamethoxam 0.05 12 60 0.75 72.80
GA Zinc Sulphur Imidacloprid 0.05 12 60 0.75 72.80
GA Zinc Sulphur Fipronil 0.05 12 60 0.6 72.65
GA Zinc Triacontanol Clothianidin 0.1 1 0.1 0.6 1.80
GA Zinc Triacontanol Thiamethoxam 0.1 1 0.1 0.6 1.80
GA Zinc Triacontanol Imidacloprid 0.1 1 0.1 0.6 1.80
GA Zinc Triacontanol Fipronil 0.1 1 0.1 0.6 1.80
GA Zinc Brassinolide Chlorantraniliprole 0.1 2 0.1 0.4 2.60
GA Zinc Brassinolide Cyantraniliprole 0.1 2 0.1 0.6 2.80
GA Zinc Brassinolide Tetraniliprole 0.1 2 0.1 0.6 2.80
GA Zinc Brassinolide Flubendiamide 0.1 2 0.1 0.7 2.90
GA Zinc Brassinolide Cartap 0.1 2 0.1 5 7.20
GA Zinc Brassinolide THO 0.1 2 0.1 5 7.20
GA Zinc Brassinolide Flupyrimin 0.1 2 0.1 2 4.20
GA Zinc Brassinolide Triflumezopyrim 0.1 2 0.1 0.25 2.45
GA Zinc Clothianidin Chlorantraniliprole 0.05 2 0.6 0.3 2.95
GA Zinc Thiamethoxam Chlorantraniliprole 0.05 2 0.6 0.3 2.35
GA Zinc Imidacloprid Chlorantraniliprole 0.05 2 0.6 0.3 2.35
GA Zinc Fipronil Chlorantraniliprole 0.05 2 0.5 0.3 2.35
GA Zinc Flupyrimin Chlorantraniliprole 0.05 2 0.7 0.3 2.35
GA Zinc Triflumezopyrim Chlorantraniliprole 0.05 2 0.3 0.3 2.35
GA Zinc Cartap Chlorantraniliprole 0.05 2 0.4 0.3 2.35
GA Zinc THO Chlorantraniliprole 0.05 2 0.4 0.3 2.35
GA Triacontanol Clothianidin Chlorantraniliprole 0.1 0.125 0.6 0.3 1.13
GA Triacontanol Thiamethoxam Chlorantraniliprole 0.1 0.125 0.6 0.3 0.53
GA Triacontanol Imidacloprid Chlorantraniliprole 0.1 0.125 0.6 0.3 0.53
GA Triacontanol Fipronil Chlorantraniliprole 0.1 0.125 0.5 0.3 0.53
GA Triacontanol Flupyrimin Chlorantraniliprole 0.1 0.125 0.7 0.3 0.53
GA Triacontanol Triflumezopyrim Chlorantraniliprole 0.1 0.125 0.3 0.3 0.53
GA Triacontanol Cartap Chlorantraniliprole 0.1 0.125 0.4 0.3 0.53
GA Triacontanol THO Chlorantraniliprole 0.1 0.125 0.4 0.3 0.53
GA Zinc Clothianidin Cyantraniliprole 0.1 2 0.6 0.3 3.00
GA Zinc Thiamethoxam Cyantraniliprole 0.1 2 0.6 0.3 2.40
GA Zinc Imidacloprid Cyantraniliprole 0.1 2 0.6 0.3 2.40
GA Zinc Fipronil Cyantraniliprole 0.1 2 0.5 0.3 2.40
GA Zinc Flupyrimin Cyantraniliprole 0.1 2 0.7 0.3 2.40
GA Zinc Triflumezopyrim Cyantraniliprole 0.1 2 0.3 0.3 2.40
GA Zinc Cartap Cyantraniliprole 0.1 2 0.4 0.3 2.40
GA Zinc THO Cyantraniliprole 0.1 2 0.4 0.3 2.40
GA Triacontanol Clothianidin Cyantraniliprole 0.1 0.125 0.6 0.3 1.13
GA Triacontanol Thiamethoxam Cyantraniliprole 0.1 0.125 0.6 0.3 0.53
GA Triacontanol Imidacloprid Cyantraniliprole 0.1 0.125 0.6 0.3 0.53
GA Triacontanol Fipronil Cyantraniliprole 0.1 0.125 0.5 0.3 0.53
GA Triacontanol Flupyrimin Cyantraniliprole 0.1 0.125 0.7 0.3 0.53
GA Triacontanol Triflumezopyrim Cyantraniliprole 0.1 0.125 0.3 0.3 0.53
GA Triacontanol Cartap Cyantraniliprole 0.1 0.125 0.4 0.3 0.53
GA Triacontanol THO Cyantraniliprole 0.1 0.125 0.4 0.3 0.53
GA Zinc Clothianidin Tetraniliprole 0.1 2 0.6 0.3 3.00
GA Zinc Thiamethoxam Tetraniliprole 0.1 2 0.6 0.3 2.40
GA Zinc Imidacloprid Tetraniliprole 0.1 2 0.6 0.3 2.40
GA Zinc Fipronil Tetraniliprole 0.1 2 0.5 0.3 2.40
GA Zinc Flupyrimin Tetraniliprole 0.1 2 0.7 0.3 2.40
GA Zinc Triflumezopyrim Tetraniliprole 0.1 2 0.3 0.3 2.40
GA Zinc Cartap Tetraniliprole 0.1 2 0.4 0.3 2.40
GA Zinc THO Tetraniliprole 0.1 2 0.4 0.3 2.40
GA Triacontanol Clothianidin Tetraniliprole 0.1 0.125 0.6 0.3 1.13
GA Triacontanol Thiamethoxam Tetraniliprole 0.1 0.125 0.6 0.3 0.53
GA Triacontanol Imidacloprid Tetraniliprole 0.1 0.125 0.6 0.3 0.53
GA Triacontanol Fipronil Tetraniliprole 0.1 0.125 0.5 0.3 0.53
GA Triacontanol Flupyrimin Tetraniliprole 0.1 0.125 0.7 0.3 0.53
GA Triacontanol Triflumezopyrim Tetraniliprole 0.1 0.125 0.3 0.3 0.53
GA Triacontanol Cartap Tetraniliprole 0.1 0.125 0.4 0.3 0.53
GA Triacontanol THO Tetraniliprole 0.1 0.125 0.4 0.3 0.53
GA Amino acid Clothianidin Tetraniliprole 0.1 2 0.6 0.4 2.50
GA Amino acid Thiamethoxam Tetraniliprole 0.1 2 0.6 0.4 2.50
GA Amino acid Imidacloprid Tetraniliprole 0.1 2 0.6 0.4 2.50
GA Amino acid Fipronil Tetraniliprole 0.1 2 0.5 0.4 2.50
GA Amino acid Flupyrimin Tetraniliprole 0.1 2 0.7 0.4 2.50
GA Amino acid Triflumezopyrim Tetraniliprole 0.1 2 0.3 0.4 2.50
GA Amino acid Cartap Tetraniliprole 0.1 2 0.4 0.4 2.50
GA Amino acid THO Tetraniliprole 0.1 2 0.4 0.4 2.50
GA Humic acid Clothianidin Cyclaniliprole 0.1 2 0.6 0.4 2.50
GA Humic acid Thiamethoxam Cyclaniliprole 0.1 2 0.6 0.4 2.50
GA Humic acid Imidacloprid Cyclaniliprole 0.1 2 0.6 0.4 2.50
GA Humic acid Fipronil Cyclaniliprole 0.1 2 0.5 0.4 2.50
GA Humic acid Flupyrimin Cyclaniliprole 0.1 2 0.7 0.4 2.50
GA Humic acid Triflumezopyrim Cyclaniliprole 0.1 2 0.3 0.4 2.50
GA Humic acid Cartap Cyclaniliprole 0.1 2 0.4 0.4 2.50
GA Humic acid THO Cyclaniliprole 0.1 2 0.4 0.4 2.50
GA Brassinolide Clothianidin Cyantraniliprole 0.1 0.02 0.6 0.4 0.52
GA Brassinolide Thiamethoxam Cyantraniliprole 0.1 0.02 0.6 0.4 0.52
GA Brassinolide Imidacloprid Cyantraniliprole 0.1 0.02 0.6 0.4 0.52
GA Brassinolide Fipronil Cyantraniliprole 0.1 0.02 0.5 0.4 0.52
GA Brassinolide Flupyrimin Cyantraniliprole 0.1 0.02 0.7 0.4 0.52
GA Brassinolide Triflumezopyrim Cyantraniliprole 0.1 0.02 0.3 0.4 0.52
GA Brassinolide Cartap Cyantraniliprole 0.1 0.02 0.4 0.4 0.52
GA Brassinolide THO Cyantraniliprole 0.1 0.02 0.4 0.4 0.52
GA Zinc Sulphur Triacontanol 0.02 10 50 0.08 60.10
GA Zinc Sulphur Brassinolide 0.02 10 50 0.02 60.04
GA Zinc Sulphur Nitrobenzen 0.02 10 50 1 61.02
GA Zinc Sulphur Salicylic acid 0.02 10 50 0.5 60.52
GA Zinc Sulphur Ortho silicic acid 0.02 10 50 0.5 60.52

GA-Gibberellic acid, Cartap-Cartap hydrochloride, THO-Thiocyclam hydrogen oxalate
Compound A Compound B active ingredients(%) Formulation Strength (%)
B1 B2 Compound A Compound
B1 B2
GA Dimethomorph Pyraclostrobin 0.2 15 10 25.20
GA Dimethomorph Metiram 0.13 10 40 50.13
GA Dimethomorph Mancozeb 0.13 10 40 50.13
GA Dimethomorph Chlorothalonil 0.08 10 30 40.08
GA Dimethomorph Propineb 0.08 10 40 50.08
GA Cyazofamid Dimethomorph 0.4 10.6 50 61.00
GA Cyazofamid Mancozeb 0.2 5.3 69.7 75.20
GA Cyazofamid Metiram 0.2 5.3 69.7 75.20
GA Oxathiapipronil Mancozeb 0.1 0.8 60 60.90
GA Oxathiapipronil Metiram 0.1 0.8 60 60.90
GA Oxathiapipronil Propineb 0.1 0.8 60 60.90
GA Oxathiapipronil Chlorothalonil 0.1 0.8 60 60.90
GA Bosacalid Pyraclostrobin 1 35 25 61.00
GA Bosacalid Azoxystrobin 1 35 25 61.00
GA Bosacalid Trifloxystrobin 1 35 25 61.00
GA Bosacalid Picoxystrobin 1 35 25 61.00
GA Difenoconazole Mancozeb 0.2 4 60 64.20
GA Difenoconazole Metiram 0.2 4 60 64.20
GA Difenoconazole Propineb 0.2 4 60 64.20
GA Difenoconazole Chlorothalonil 0.2 4 60 64.20
GA Prothioconazole Mancozeb 0.2 5 60 65.20
GA Prothioconazole Metiram 0.2 5 60 65.20
GA Prothioconazole Propineb 0.2 5 60 65.20
GA Prothioconazole Chlorothalonil 0.2 5 60 65.20
GA Fluxapyroxad Mancozeb 0.2 6 60 66.20
GA Fluxapyroxad Metiram 0.2 6 60 66.20
GA Fluxapyroxad Propineb 0.2 6 60 66.20
GA Fluxapyroxad Chlorothalonil 0.2 6 60 66.20
GA Fluxapyroxad Pyraclostrobin 0.5 15 15 30.50
GA Fluxapyroxad Azoxystrobin 0.5 15 15 30.50
GA Fluxapyroxad Trifloxystrobin 0.5 15 15 30.50
GA Fluxapyroxad Picoxystrobin 0.5 15 15 30.50
GA Fluxapyroxad Difenoconazole 0.5 15 10 25.50
GA Fluxapyroxad Tebuconazole 0.5 15 20 35.50
GA Fluxapyroxad Prothioconazole 0.5 15 15 30.50
GA Fluxapyroxad Epoxiconazole 0.5 15 15 30.50
GA Sulphur Pyraclostrobin 0.133 60 5 65.13
GA Sulphur Azoxystrobin 0.133 60 5 65.13
GA Sulphur Trifloxystrobin 0.133 60 5 65.13
GA Sulphur Picoxystrobin 0.133 60 5 65.13
GA Sulphur Chlorothalonil 0.100 50 25 75.10
GA Sulphur Propineb 0.100 50 25 75.10
GA Sulphur Metiram 0.100 50 25 75.10
GA Sulphur Mancozeb 0.100 50 25 75.10
GA Sulphur Hexaconazole 0.2 60 4 64.20
GA Sulphur Difenoconazole 0.2 60 5 65.20
GA Sulphur Epoxiconazole 0.2 60 7.5 67.70
GA Sulphur Prothioconazole 0.2 60 7.5 67.70
GA Sulphur Propiconazole 0.2 60 7.5 67.70
GA Sulphur Fluxapyroxad 0.2 60 5 65.20
GA Sulphur Penthiopyrad 0.2 60 10 70.20
GA Sulphur Penflufen 0.2 60 10 70.20
GA Sulphur Carbendazim 0.2 60 20 80.20
GA Sulphur Thiophanate methyl 0.2 60 20 80.20
GA Sulphur Validamycin 0.2 60 5 65.20
GA Sulphur Kasugamycin 0.2 60 5 65.20
GA Sulphur Thifluzamide 0.2 60 6 66.20
GA Sulphur Prochloraz 0.2 60 6 66.20
GA Sulphur Pencycuron 0.2 60 6 66.20

The composition of the present invention in addition to bioactive amounts of active ingredients further comprises inactive formulation excipients for Granule formulation including but not to limited to dispersing agent, wetting agent, antifoaming agent, carrier.
Examples of dispersing agent used herein for Granule formulation include but not limited to alkylnaphthalene sulfonate sodium salt, sodium polycarboxylate, naphthalene sulfonic acid, sodium salt condensates with formaldehyde, polyalcoxylated alkylphenol, naphthalene sulfonic acid formaldehyde condensate, phenol sulfonic acid urea formaldehyde condensate, methyl naphthalene-formaldehyde-condensate sodium salt, naphthalene condensates, polyacrylates and phosphate esters, calcium lignosulfonate, sodium lignosulfonate, sodium lignosulfonate-sulfomethylated.
A wetting agent is a substance that when added to a liquid increases the spreading or penetration power of the liquid by reducing the interfacial tension between the liquid and the surface on which it is spreading. Wetting agents are used for two main functions in agrochemical formulations: during processing and manufacture to increase the rate of wetting of powders in water to make concentrates for soluble liquids or suspension concentrates; and during mixing of a product with water in a spray tank or other vessel to reduce the wetting time of wettable powders and to improve the penetration of water into water-dispersible granules.
Examples of wetting agent used herein for Granule formulation include but not limited to sodium N-methyl-N-oleoyl taurate, alkyl naphthalene sulfonate-sodium salt, mixture of isomers of dibutyl naphthalene sulphonic acid sodium salt, sodium di-isopropyl naphthalene sulphonate, sodium Lauryl sulfate, dioctyl sulfate, phosphate esters, sulphosuccinates and non-ionic such as tridecyl alcohol ethoxylate, alkyl or alkaryl sulfonates such as alkylbenzene sulfonates, alpha olefin sulfonate, ethoxylated or non-ethoxylated alkyl or alkaryl carboxylates, alkyl or alkaryl phosphate esters, alkyl polysaccharide, di or mono alkyl sulfosuccinate derivatives, alpha olefin sulfonates, di-alkyl sulphosuccinates, butyl, dibutyl, isopropyl and di-isopropyl naphthalene sulfonate salts, C12 alkyl benzene sulfonate or C10-C16 alkyl benzene sulfonate, organosilicons surfactants includes trisiloxane ethoxylate, polyoxyethylene methyl polysiloxane, polyoxyalkylene methyl polysiloxane, polyether polymethyl siloxane copolymer, trisiloxane heptamethyl, Polyalkyleneoxide modified heptamethyl trisiloxane, polyether modified polysiloxane, may or may not be in modified form, may be liquid or powder form or mixture thereof etc.
Examples of antifoaming agent used herein for Granule formulation include but not limited to polydimethylsiloxane.
Examples of carrier used herein for Granule formulation include but not limited to china clay, silica, lactose anhydrous, lactose monohydrate, ammonium sulphate, sodium sulphate anhydrous, corn starch, urea, EDTA, sand granules (silicon dioxide), urea formaldehyde resin, diatomaceous earth, kaolin, bentonite, kieselguhr, fuller's earth, attapulgite clay, bole, loess, talc, chalk, dolomite, limestone, lime, calcium carbonate, powdered magnesia, magnesium oxide, magnesium sulphate, sodium chloride, gypsum, calcium sulphate, pyrophyllite, silicates and silica gels; fertilizers such as, for example, ammonium sulphate, ammonium phosphate, ammonium nitrate and urea; natural products of vegetable origin such as, for example, grain meals and flours, bark meals, wood meals, nutshell meals and cellulosic powders; and synthetic polymeric materials such as, for example, ground or powdered plastics and resins, bentonites, zeolites, titanium dioxide, iron oxides and hydroxides, aluminium oxides and hydroxides, or organic materials such as bagasse, charcoal, or synthetic organic polymers.
The composition of the present invention in addition to bioactive amounts of active ingredients further comprises inactive formulation excipients for sand coated granule (GR) and Controlled Release Granule (CR-GR) formulation including but not to limited to wetting agent, dispersing agent, solvent, carrier, colouring agent and controlled release agent.
Examples of dispersing agent used herein for sand coated granule (GR) and Controlled Release Granule (CR-GR) formulation include but not limited to Copolymer of propylene oxide (PO) and ethylene oxide (EO) and/or an ethoxylated tristyrene phenol, copolymer of PO and EO is alpha-butyl-omega-hydroxypoly (oxypropylene) block polymer with poly(oxyethylene), ethoxylated tristyrene phenol is alpha-[2,4,6-tris[1-(phenyl)ethyl] phenyl]-omega-hydroxy poly(oxyethylene, poly(oxy-1,2-ethanediyl)-alpha-C10-15alkyl-omega-hydroxy phosphate or sulphate and/or a C10-13alkylbenzenesulfonic acid, tristyrylphenols, nonylphenols, Di nonylphenol and octyl phenols, styryl phenol polyethoxyester phosphate, alkoxylated C14-20fatty amines.
Examples of wetting agent used herein for sand coated granule (GR) and Controlled Release Granule (CR-GR) formulation include but not limited to Mono C2-6 alkyl ether of a poly C2-4alkylene oxide block copolymer, condensation product of castor oil and polyC2-4alkylene oxide, alkoxylated castor oil, carboxylates, sulphates, sulphonates, alcohol ethoxylates, alkyl phenol ethoxylates, fatty acid ethoxylates, sorbitan esters, ethoxylated fats or oils, amine ethoxylates, phosphate esters, ethylene oxide - propylene oxide copolymers, fluorocarbons, polyethylene glycol resin, polyalkylene glycol ether, polyalkoxylated nonyl phenyl, alkoxylated primary alcohol, ethoxylated distyrylphenol, ethoxylated distyrylphenol sulphate, ethoxylated tristyrylphenol phosphate, tristyrylphenol phosphate ester, hydroxylated stearic acid polyalkylene glycol polymer, and their corresponding salts, ethoxylated distyrylphenol, ethoxylated distyrylphenol sulphate, ethoxylated tristyrylphenol phosphate, tristyrylphenol phosphate ester, tristyrylphenol phosphate potassium salt, sodium dodecyl sulfate (SDS).
Examples of solvent used herein for sand coated granule (GR) and Controlled Release Granule (CR-GR) formulation include but not limited to Fatty acid methyl ester, cyclohexane, xylene, mineral oil or kerosene, mixtures or substituted naphthalene, mixtures of mono- and polyalkylated aromatics, dibutyl phthalate or dioctyl phthalate, ethylene glycol monomethyl or mono ethyl ether, butyrolactone, octanol, castor oil, soybean oil, cottonseed oil, epoxidised coconut oil or soybean oil, aromatic hydrocarbons, dipropyleneglycol monomethyl ether, polypropylene glycol [M.W. 2000-4000], polyoxyethylene polyoxypropylene glycols, polyoxypropylene polyoxyethylene glycols, diethyleneglycol, polyethylene glycol [M.W. 200-4000 amu], methoxy polyethylene glycols 350, 550, 750, 2000, 5000; glycerol, methyl oleate, n-octanol, alkyl phosphates such as tri-n-butyl phosphate, propylene carbonate and isoparaffinic, tetrahydrofurfuryl alcohol, gamma-butyrolactone, N-methyl-2-pyrrolidone, tetramethylurea, dimethylsulfoxide, N,N-dimethylacetamide , Diacetone alcohol, Polybutene, Propylene carbonate, Di propylene glycol isomer mixture.
Examples of carrier used herein for sand coated granule (GR) and Controlled Release Granule (CR-GR) formulation include but not limited to Diatomaceous earth, attapulgite or zeolites, dolomite, limestone, silica, fly ash, hydrated lime, wheat flour, wood flour, sand granules (silicon dioxide), ground wheat straw, cellulose and soy flour, bentonite, kaolin, attapulgite, diatomaceous earth, calcium carbonate, talc, muscovite mica, fused sodium potassium, aluminum silicate , perlite, talc and muscovite mica, urea, sulfur-coated urea, isobutylidene diurea, ammonium nitrate, ammonium sulfate, ammonium phosphate, triple super phosphate, phosphoric acid, potassium sulfate, potassium nitrate, potassium metaphosphate, potassium chloride, dipotassium carbonate, potassium oxide and a combination of these. calcium, magnesium, sulfur, iron, manganese, copper, zinc; oxides, humic acid, Wood floor, Calcium silicate, Cellulose granules, Magnesium stearate
Examples of colouring agent used herein for sand coated granule (GR) and Controlled Release Granule (CR-GR) formulation include but not limited to Crystal violet, Thalocyano dye chlorinated, Aerosol green FFB dye, Rodamine, Azo compound.
Examples of controlled release agent used herein for sand coated granule (GR) and Controlled Release Granule (CR-GR) formulation include but not limited to Xanthan gum, PVK, carboxymethyl celluloses, polyvinyl alcohols, gelatin, sodium carboxymethylcellulose, hydroxyethylcellulose, Sodium Polyacrylate, modified starch, Paraffin wax, Polyvinyl acetate,Montan wax and vinyl acetate, Polyethylene Glycol 6000, Cationic hydro soluble polymer, C4 alkylated Polyvinyl pyrrolidone.
EXAMPLE 1:
Recipe, storage stability and mfg process.
GA 0.1%+Zinc 12%+Sulphur 60% Granule (Recipe: GZnS 721) [Recipe use in Experiment 1
Chemical composition Percent (w/w)
Gibberellic acid (GA) 0.10
Zinc 12.00
Sulphur 60.00
Ligno sulfonate 12.50
Phenol sulfonic acid urea formaldehyde condensate 8.00
Naphthalene sulfonic acid formaldehyde condensate 5.00
Polydimethyl siloxane 0.50
China clay 1.19
Total 100.00

Storage stability study in laboratory (at 54±2 ? & at 0±2 ? for 14 days) and at room temperature (for 12 months) shows that GA 0.1%+Zinc 12%+Sulphur 60% Granule formulation complies all the in-house parameters like active ingredients content, suspensibility-minimum 70%, pH range-6 to 9, wettability-maximum 60 second, wet sieve-minimum 98.5% by mass, bulk density- 0.45 to 0.65 (g/ml), moisture content-maximum 2% by mass.

Manufacturing process for preparing 100 kg sample of GA 0.1%+Zinc 12%+Sulphur 60% Granule (Recipe: GZnS 721):
Step 1-Take 70 kg water and add 12.5 kg of ligno sulfonate, 8.0 kg of Phenol sulfonic acid urea formaldehyde condensate, 5.0 kg of Naphthalene sulfonic acid formaldehyde condensate and 0.5 kg of Polydimethylsiloxane into a vessel having high speed homogenizer.
Step 2-Add 0.1 kg of Gibberellic acid, 12.0 kg of Zinc oxide and 60.0 kg of Sulphur, now homogenize using high shear homogenizer for 30-45 minutes.
Step 3-Now add 2.4 kg of China clay and homogenize using high shear homogenizer for 30-45 minutes.
Step 4-Mill this premix using Sand mill until D90 is less than 10 microns.
Step 5-Now spray this slurry in spray dryer at specific temperature to get granules from range of 0.1 to 50 microns and remove excess 70 kg water.
Step 6-Finally send samples to QC for quality check.

EXAMPLE 2:
GA 0.08%+Fipronil 0.6%+Clothianidin 0.75% GR (Recipe: GFC 143) Sand coated granule, ready to use [Recipe use in Experiment 2]
Chemical composition Percent (w/w)
Gibberellic acid 0.08
Fipronil 0.60
Clothianidin 0.75
PEG 6000 (Polyethylene glycol 6000) 2.00
Diacetone alcohol 5.00
Copolymer butanol EO/PO 2.00
Silica 2.50
Sand (Silicon dioxide) 86.87
Dye or colourant 0.20
Total 100.00

Storage stability study in laboratory (at 54±2 ? & at 0±2 ? for 14 days) and at room temperature (for 12 months) shows that GA 0.08%+Fipronil 0.6%+Clothianidin 0.75% GR formulation complies all the in-house parameters like active ingredients content, pH range- 6 to 9, dustiness <20 mg, dry sieve-minimum 90% by mass, attrition resistance (for <100 micron) < 5%, moisture content-maximum 2% by mass.

Manufacturing process for preparing 100 kg sample of GA 0.08%+Fipronil 0.6%+Clothianidin 0.75% GR (Recipe: GFC 143):
Step 1-Mix 0.08 kg of Gibberellic acid, 0.60 kg of Fipronil and 0.75 kg of Clothianidin technical in 5.0 kg of Diacetone alcohol. Now add 2.0 kg of Copolymer butanol EO/PO, 2.0 kg of PEG 400 and 0.20 kg of dye or colorant.
Step 2-Spray this premix on sand granules and homogenize for 30-45 minutes.
Step 3-Now add 2.50 KG OF Silica on these coated granules for making them free-flow.
Step 4-Send sample for QC check and then pack in required packing.

EXAMPLE 3:
GA 1%+Zinc 5%+Cyantraniliprole 30% Granule (Recipe-GZCY 360)
[Recipe use in Experiment 3]
Chemical composition Percent (w/w)
Gibberellic acid 1.00
Zinc 5.00
Cyantraniliprole 30.00
Polyalkyleneoxide modified heptamethyltrisiloxane 3.00
Alkyl naphthalene sulfonate-sodium salt 3.00
Sodium lignosulfonate 30.00
Polydimethyl siloxane 0.50
Sodium sulphate anhydrous 6.00
Urea formaldehyde resin 5.00
China Clay 16.50
Total 100.00

Storage stability-GA 1%+Zinc 5%+Cyantraniliprole 30% Granule
Laboratory storage stability for 14 days
Parameters Specification (in house) Initial At 54±2 0C At 0±2 0C
Gibberellic acid content percent by mass 0.95 to 1.10 1.09 1.05 1.09
Zinc content percent by mass 4.75 to 5.50 5.21 5.15 5.19
Cyantraniliprole content percent by mass 28.50 to 31.50 30.25 30.18 30.24
Gibberellic acid suspensibility percent min. 70 98.26 96.45 98.12
Zinc suspensibility percent min. 70 97.68 96.84 97.15
Cyantraniliprole suspensibility percent min. 70 97.46 96.24 97.12
pH range (1% aq. Suspension) 6 to 9 6.6 6.5 6.6
Wettability (in second, maximum) 60 7 8 8
wet sieve (45 micron) percent by mass min. 98.5 99.6 99.2 99.4
bulk density (g/ml) 0.45 to 0.65 0.5 0.5 0.5
moisture content percent by mass max. max. 3% 2.5 2.6 2.5
Room temperature storage stability up to 12 months
Parameters Specification (in house) 1 month 6 months 12 months
Gibberellic acid content percent by mass 0.95 to 1.10 1.09 1.09 1.09
Zinc content percent by mass 4.75 to 5.50 5.21 5.21 5.20
Cyantraniliprole content percent by mass 28.50 to 31.50 30.25 30.25 30.24
Gibberellic acid suspensibility percent min. 70 98.25 97.75 96.40
Zinc suspensibility percent min. 70 97.65 97.38 96.80
Cyantraniliprole suspensibility percent min. 70 97.45 97.15 96.20
pH range (1% aq. Suspension) 6 to 9 6.6 6.5 6.4
wettability sec. max. 60 7 7 8
wet sieve (45 micron) percent by mass min. 98.5 99.5 99.4 99.2
bulk density (g/ml) 0.45 to 0.65 0.5 0.5 0.5
moisture content percent by mass max. max. 3% 2.5 2.5 2.5

Storage stability study in laboratory (at 54±2 ? & at 0±2 ? for 14 days) and at room temperature (for 12 months) shows that GA 1%+Zinc oxide 5%+Cyantraniliprole 30% Granule formulation complies all the in-house parameters like active ingredients content, suspensibility, pH range, wettability, wet sieve (45 micron), bulk density and moisture content.
Manufacturing process for preparing 100 kg sample of GA 1%+Zinc 5%+ Cyantraniliprole 30% Granule:
Step 1-Take 70 kg water and add 3.0 kg of Alkyl naphthalene sulfonate-sodium salt, 30.0 kg of Sodium lignosulfonate and 0.50 kg of Polydimethyl siloxane into a vessel having high speed homogenizer.
Step 2-Add 1.0 kg of Gibberellic acid, 5.0 kg of Zinc oxide and 30.0 kg of Cyantraniliprole technical and homogenize using high shear homogenizer for 30-45 minutes.
Step 3-Now add 6.0 kg of Sodium Sulfate anhydrous, 5.0 kg of Urea formaldehyde resin and 16.50 kg of China clay, 3.0 kg of Polyalkyleneoxide modified heptamethyltrisiloxane and homogenize using high shear homogenizer for 30-45 minutes.
Step 4-Mill this premix using Sand mill until D90 is less than 10 microns.
Step 5-Now spray this slurry in spray dryer at specific temperature (inlet temperature below 150 C degree and outer temperature less than 85 C degree) to get granules from range o f 0.1 to 50 microns and remove excess 70 kg water.
Step 6-Finally send samples to QC for quality check.

EXAMPLE 4:
GA 0.1%+Sulphur 60%+Tetraniliprole 0.5% Granule (Recipe: GST 606) [Recipe use in Experiment 4]
Chemical composition Percent (w/w)
Gibberellic acid 0.10
Sulphur 60.00
Tetraniliprole 0.50
Lignin Sulfonate 12.50
Phenol sulfonic acid urea formaldehyde condensate 8.00
Naphthalene sulfonic acid formaldehyde condensate 5.00
Polydimethyl siloxane 0.50
China Clay 13.40
Total 100.00

Storage stability study in laboratory (at 54±2 ? & at 0±2 ? for 14 days) and at room temperature (for 12 months) shows that GA 0.1%+Sulphur 60%+Tetraniliprole 0.5% Granule formulation complies all the in-house parameters like active ingredients content, suspensibility-minimum 70%, pH range-6 to 9, wettability-maximum 60 second, wet sieve-minimum 98.5% by mass, bulk density- 0.45 to 0.65 (g/ml), moisture content-maximum 2% by mass.
Manufacturing process for 100 kg samples of GA 0.1%+Sulphur 60%+Tetraniliprole 0.5% Granule (Recipe: GST 606):
Step 1-Take 70 kg water and add 12.5 kg of lignin sulfonate, 8.0 kg of Phenol sulfonic acid urea formaldehyde condensate, 5.0 kg of Naphthalene sulfonic acid formaldehyde condensate and 0.5 kg of Polydimethylsiloxane into a vessel having high speed homogenizer.
Step 2-Add 0.1 kg of Gibberellic acid, 60 kg of Sulphur and 0.5 kg of Tetraniliprole technical, Now homogenize using high shear homogenizer for 30-45 minutes.
Step 3-Now add 13.9 kg of China clay and homogenize using high shear homogenizer for 30-45 minutes.
Step 4-Mill this premix using Sand mill until D90 is less than 10 microns.
Step 5-Now spray this slurry in spray dryer at specific temperature to get granules from range of 0.1 to 50 microns and remove excess 70 kg water.
Step 6-Finally send samples to QC for quality check.

EXAMPLE 5:
GA 0.05%+Sulphur 60%+Zinc 12%+Fipronil 0.6% Granule (Recipe:GSZF 726) [Recipe use in Experiment 5]
Chemical composition Percent (w/w)
Gibberellic acid 0.05
Sulphur 60.00
Zinc 12.00
Fipronil 0.60
Lignin Sulfonate 10.00
Phenol sulfonic acid urea formaldehyde condensate 4.00
Naphthalene sulfonic acid formaldehyde condensate 4.00
Polydimethyl siloxane 0.50
China Clay 8.85
Total 100.00

Storage stability study in laboratory (at 54±2 ? & at 0±2 ? for 14 days) and at room temperature (for 12 months) shows that GA 0.05%+Sulphur 60%+Zinc oxide 12%+Fipronil 0.6% Granule formulation complies all the in-house parameters like active ingredients content, suspensibility-minimum 70%, pH range-6 to 9, wettability-maximum 60 second, wet sieve-minimum 98.5% by mass, bulk density- 0.45 to 0.65 (g/ml), moisture content-maximum 2% by mass.
Manufacturing process for preparing 100 kg samples of GA 0.05%+Sulphur 60%+Zinc 12%+Fipronil 0.6% Granule (Recipe: GSZF 726):
Step 1-Take 70 kg water and add 10 kg of lignin sulphonate, 4.0 kg of Phenol sulfonic acid urea formaldehyde condensate, 4.0 kg of Naphthalene sulfonic acid formaldehyde condensate and 0.5 kg of Polydimethylsiloxane into a vessel having high speed homogenizer.
Step 2-Add 0.05 kg of Gibberellic acid, 60 kg of Sulphur, 12 kg of Zinc oxide and 0.6 kg of Fipronil technical, Now, homogenize using high shear homogenizer for 30-45 minutes.
Step 3-Now add 9.35 kg of China clay and homogenize using high shear homogenizer for 30-45 minutes.
Step 4-Mill this premix using Sand mill until D90 is less than 10 microns.
Step 5-Now spray this slurry in spray dryer at specific temperature to get granules from range of 0.1 to 50 microns and remove excess 70 kg water.
Step 6-Finally send samples to QC for quality check.

EXAMPLE 6:
GA 0.05%+Sulphur 50%+Zinc 10%+Chlorantraniliprole 0.4% Granule (Recipe: GSZC 604) [Recipe used in Experiment 6]
Chemical composition Percent (w/w)
Gibberellic acid 0.05
Sulphur 50.00
Zinc 10.00
Chlorantraniliprole 0.40
Lignin Sulfonate 9.00
Phenol sulfonic acid urea formaldehyde condensate 3.50
Naphthalene sulfonic acid formaldehyde condensate 3.50
China Clay 23.55
Total 100.00

Storage stability study in laboratory (at 54±2 ? & at 0±2 ? for 14 days) and at room temperature (for 12 months) shows that GA 0.05%+Sulphur 50%+Zinc 10%+ Chlorantraniliprole 0.4% Granule formulation complies all the in-house parameters like active ingredients content, suspensibility-minimum 70%, pH range-6 to 9, wettability-maximum 60 second, wet sieve-minimum 98.5% by mass, bulk density- 0.45 to 0.65 (g/ml), moisture content-maximum 2% by mass.
Manufacturing process for preparing 100 kg sample of GA 0.05%+Sulphur 50% +Zinc 10%+Chlorantraniliprole 0.4% Granule (Recipe:GSZC 604):
Step 1-Take 80 kg water and add 9 kg of lignin sulphonate, 3.5 kg of Phenol sulfonic acid urea formaldehyde condensate, 3.5 kg of Naphthalene sulfonic acid formaldehyde condensate into a vessel having high speed homogenizer.
Step 2-Add 0.05 kg of Gibberellic acid, 50 kg of Sulphur, 10 kg of Zinc oxide and 0.4 kg of Chlorantraniliprole technical, Now homogenize using high shear homogenizer for 30-45 minutes.
Step 3-Add 23.55 kg of China clay and homogenize using high shear homogenizer for 30-45 minutes.
Step 4-Mill this premix using sand mill until D90 is less than 10 microns.
Step 5-Now spray this slurry in spray dryer at specific temperature to get granules from range of 0.1 to 50 microns and remove excess 80 kg water.
Step 6-Finally send samples to QC for quality check.

EXAMPLE 7:
GA 0.1%+Triacontanol 0.1%+Zinc 2%+Chlorantraniliprole 0.4% GR (Recipe: GTZC 260) Sand coated granule, ready to use [Recipe use in Experiment 7]
Chemical composition Percent (w/w)
Gibberellic acid 0.10
Triacontanol 0.10
Zinc 2.00
Chlorantraniliprole 0.40
PEG 6000 (Polyethylene glycol 6000) 2.00
Diacetone alcohol 5.00
Copolymer butanol EO/PO 2.00
Silica 2.50
Sand (Silicon dioxide) 86.87
Dye or colourant 0.20
Total 101.17

Storage stability study in laboratory (at 54±2 ? & at 0±2 ? for 14 days) and at room temperature (for 12 months) shows that GA 0.1%+Triacontanol 0.1%+Zinc 2%+Chlorantraniliprole 0.4% GR formulation complies all the in-house parameters like active ingredients content, pH range- 6 to 9, dustiness <20 mg, dry sieve-minimum 90% by mass, attrition resistance (for <100 micron) < 5%, moisture content-maximum 2% by mass.
Manufacturing process for preparing 100 kg sample of GA 0.1%+Triacontanol 0.1%+Zinc 2%+Chlorantraniliprole 0.4% GR (Recipe: GTZC 260):
Step 1-Mix 0.1 kg of Gibberellic acid, 0.1 kg of Triacontanol, 2 kg of Zinc lactate gluconate and 0.4 kg of Chlorantraniliprole technical in 5.0 kg of Diacetone alcohol.
Step 2-Now add 2.0 kg of Copolymer butanol EO/PO, 2.0 kg of PEG 400 and 0.20 kg of dye or colorant.
Step 3-Spray this premix on sand granules and homogenize for 30-45 minutes.
Step 4-Now add 2.50 KG OF Silica on these coated granules for making them free-flow.
Step 5-Send sample for QC check and then pack in required packing.

EXAMPLE 8:
GA 2.32%+Chlorantraniliprole 35% Granule (Recipe: GAC 373)
[Recipe use in Experiment 8]
Chemical composition Percent (w/w)
Gibberellic acid 2.32
Chlorantraniliprole 35.00
Sodium alkyl naphthalene sulfonate 0.50
Sodium lignosulfonate 3.00
Sodium lignosulfonate, sulfomethylated 6.00
Polydimethyl siloxane 0.50
Amorphous silica 0.50
Sucrose 1.00
Clay 8.00
Lactose monohydrate 43.18
Total 100.00

Storage stability study in laboratory (at 54±2 ? & at 0±2 ? for 14 days) and at room temperature (for 12 months) shows that GA 2.32%+Chlorantraniliprole 35% Granule formulation complies all the in-house parameters like active ingredients content, suspensibility-minimum 70%, pH range-6 to 9, wettability-maximum 60 second, wet sieve-minimum 98.5% by mass, bulk density- 0.45 to 0.65 (g/ml), moisture content-maximum 2% by mass.
Manufacturing process for preparing 100 kg sample of GA 2.32%+ Chlorantraniliprole 35% Granule (Recipe:GAC 373):
Step 1-Charge 43.18 kg of Lactose monohydrate, 0.5 kg of Amorphous silica, 1.0 kg of sucrose, 8.0 kg of China clay, 6.0 kg of Sodium lignosulfonate, sulfomethylated ,3.0 kg of Sodium lignosulfonate and 0.5 kg of Sodium alkyl naphthalene sulfonate into a Ribbon Blender under very slow speed avoiding dust and blend for 30-45 minutes.
Step 2- Now, charge 35.0 kg of Chlorantraniliprole technical and 2.32 kg of Gibberellic acid slowly avoiding dust and blend till it gets a homogenous powder.
Step 3-Mill this homogeneous powder using Air Jet Mill or Air Classifier Mill to get required particle size (D90<20 micron).
Step 4- Now again blend this milled powder and then add required quantity of water having 0.5 kg of Polydimethyl siloxane to make dough required for extrusion.
Step 5- Extrude this dough using Basket extruder using sieve size from 0.6 to 1.0 mm and then dry these extruded granules to remove extra added water using Fluid Bed Dryer having inlet air temperature 55-60 degree Celsius.
Step 6- Send this final formulation to QC for quality check.

EXAMPLE 9:
GA 0.3%+Flonicamid 12%+Tolfenpyrad 15% Granule (Recipe: GFT 273) [Recipe used in Experiment 9]
Chemical composition Percent (w/w)
Gibberellic acid 0.30
Flonicamid 12.00
Tolfenpyrad 15.00
Polyalkyleneoxide modified heptamethyltrisiloxane 3.00
Alkyl naphthalene sulfonate-sodium salt 3.00
Sodium lignosulfonate 30.00
Polydimethyl siloxane 0.50
Sodium sulphate anhydrous 6.00
Urea formaldehyde resin 5.00
China Clay 25.20
Total 100.00

Storage stability study in laboratory (at 54±2 ? & at 0±2 ? for 14 days) and at room temperature (for 12 months) shows that GA 0.3%+Flonicamid 12%+Tolfenpyrad 15% Granular formulation complies all the in-house parameters like active ingredients content, suspensibility-minimum 70%, pH range-6 to 9, wettability-maximum 60 second, wet sieve-minimum 98.5% by mass, bulk density- 0.45 to 0.65 (g/ml), moisture content-maximum 2% by mass.
FIELD BIO-EFFICACY STUDIES:
The granular formulations of Gibberellic acid (GA)+plant health additives (PHA), GA+PHA+PHA, GA+insecticide, GA+insecticide+insecticide, GA+PHA+insecticide, GA+PHA+PHA+insecticide, GA+fungicide, GA+fungicide+fungicide, GA+PHA +fungicide, GA+PHA+fungicide+fungicide, GA+insecticide+fungicide has been developed in the laboratory and evaluated for its synergistic action in terms of efficacy, residual control and comparison with conventional formulations and tank mixes.
A synergistic effect exists wherever the action of a combination of active ingredient is greater than the sum of the action of each of the components alone. Therefore, a synergistically effective amount or an effective amount of a synergistic composition or combination is an amount that exhibits greater pesticidal activity than the sum of the pesticidal activities of the individual components.
In the field of agriculture, it is often understood that the term “synergy” is as defined by Colby S.R. in an article entitled “ Calculation of the synergistic and antagonistic responses of herbicide combinations” published in the journal Weeds, 1967, 15, p.20-22, incorporated herein by reference in its entirety. The action expected for a given combination of two or three active components can be calculated as follows:

Experiment 1: Composition for enhancing rice grain yield
Crop : Rice
Location : Raipur, Chhattisgarh
Treatments : Twenty
Replications : Three
Plot size : 33.33 sq.m.
Application method : Soil application-manual broadcasting in the soil at 7 days after transplanting (DATP).
Observation Methods:
Plant vigor: plant vigor observations recorded on the scale of 1 to 10. The visual observations on plant vigor includes growth of above ground parts (number of tillers, leaves-size, color, plant height and over all biomass), below ground parts (root biomass-number of primary, secondary, ternary roots/rootlets, root length).
Panicles bearing tillers: Count the number of panicles bearing tillers per 1 sq.m. area. Record the observations from 5 spots per plot at before harvest.
Grain yield: Record the grain yield (kg) per plot at harvest.
Table 1: Treatment details
Treatment number Treatment details Formulation (kg) per hectare gram active ingredient per hectare
T1 GA 0.1%+Zinc oxide 12%+Sulphur 60% Granule (Recipe: GZnS 721) 10 kg 10+1200+6000=7210
T2 GA 0.1%+Zinc oxide 12%+Triacontanol 0.1% Granule 10 kg 10+1200+10=1220
T3 GA 0.1% GR+Zinc oxide 90% WP 10 kg+1.333 kg 10+1200=1210
T4 GA 0.1% GR+Sulphur 80% WG 10 kg+7.5 kg 10+6000=6010
T5 GA 0.1% GR+Triacontanol 0.05% GR 10 kg+20 kg 10+10=20
T6 Zinc oxide 90% WP+Sulphur 80% WG 1.333 kg+7.5 kg 1200+6000=7200
T7 Zinc oxide 90% WP+Triacontanol 0.05% GR 1.333 kg+20 kg 1200+10=1210
T8 GA 0.1% GR 10 kg 10
T9 Zinc oxide 90% WP 1.333 kg 1200
T10 Sulphur 80% WG 7.5 kg 6000
T11 Triacontanol 0.05% GR 20 kg 10
T12 GA 0.1%+Triacontanol 0.1% GR 10 kg 10+10=20
T13 Zinc 14%+Sulphur 67% MG 10 kg 1400+6700=8100
T14 UTC (Untreated Control) - -
GA-Gibberellic Acid, WP wettable powder, WG wettable granule, GR sand coated granule, MG Micro Granule, T1 and T2-novel granular composition. T3 to T7-conventional on farm mixing of market available products. T8 to T13-market available products.

Table 2: Effect on yield and yield attributing characters in rice crop
Treatment number Plant vigour (1-10 scale) Number of Panicles bearing tillers % increase in panicles bearing tillers over T14 Grain yield (kg/plot) % increase in grain yield
over T14 over T13 over T12
T1 10.00 441.0 61.78 2.24 84.89 20.23 19.31
T2 10.00 440.3 61.52 2.23 83.52 18.29 17.37
T3 8.00 402.6 47.69 1.87 54.40
T4 8.33 416.0 52.60 2.01 65.38
T5 8.33 420.6 54.29 2.06 69.51
T6 8.00 408.6 49.89 1.94 60.16
T7 7.67 405.3 48.68 1.92 58.52
T8 6.00 306.6 12.47 1.55 28.02
T9 6.33 320.3 17.50 1.62 33.24
T10 6.67 328.6 20.54 1.66 36.81
T11 6.00 305.3 12.00 1.51 24.73
T12 8.67 421.0 54.44 2.08 71.15
T13 8.00 422.3 54.92 2.07 70.60
T14 5.67 272.6 0.00 1.21 0.00

The novel granular T1 and T2 treatments shows excellent plant vigor and bears higher number of panicles and yield higher grain yield as compared to all conventional treatments including on farm mixes and market available products. The novel granular composition (T1, T2) produces higher grain yield compared to T12 (GA 0.1%+Triacontanol 0.1% GR) and T13 (Zinc 14%+Sulphur 67% MG). The visual observations of novel granular composition (T1, T2) shows excellent crop growth in terms of vegetative and reproductive part which leads to higher grain yield with excellent grain quality (shiny golden color, bold size grains) as compared to all conventional treatments. The novel granular composition (T1, T2) does not shows any kind of phytotoxicity symptoms.
Experiment 2: Effect of novel granular composition of GA+Insecticide+Insecticide on insect control and yield attributing characters in rice crop
Crop : Rice
Location : Dhamtari, Chattishgarh
Plot size : 33.33 sq.m.
Number of Treatments: Twenty
Replication : Two
Method of Application: Soil application-manual broadcasting of granules at 15 DATP (Days after transplanting)
Observation Methods:
Stem borer control (%): Stem borer causes damage as dead heart(damaged tiller) symptoms in vegetative growth stage and white ear (tillers with damaged ear head/panicles) symptoms in reproductive stage.
Dead heart symptoms: Count the number of healthy and damaged tillers (dead heart) per hill. Record the observations from 10 hills per plot. Calculate Dead Heart (%) incidence and recalculate stem borer(%) control.
White ear symptoms: Count the number of tillers with healthy earhead and white ear per hill. Record the observations from 10 hills per plot. Calculate white ear incidence (%) and recalculate stem borer control(%).




Grain yield: Record the grain yield (kg) per plot at harvest.
The observed value of stem borer control (%) as dead heart symptoms and white ear used to worked out the Colby’s formula to judge the synergism.
Table 3: Treatment details
Treatment number Treatment details Formulation (kg) per hectare gram active ingredient per hectare
T1 GA 0.08%+Fipronil 0.6%+Clothianidin 0.75% GR (Recipe: GFC 143) 10 kg 8+60+75
T2 GA 0.08%+Fipronil 0.6%+Thiamethoxam 1% GR 10 kg 8+60+100
T3 GA 0.08%+Fipronil 0.6%+Imidacloprid 0.75% GR 10 kg 8+60+75
T4 GA 0.08%+Fipronil 0.6%+Bifenthrin 0.75% GR 10 kg 8+60+75
T5 GA 0.1% GR +Fipronil 0.3% GR (on farm mixing) 8 kg+20 kg 8+60
T6 GA 0.1% GR +Clothianidin 0.5% GR (on farm mixing) 8 kg+15 kg 8+75
T7 GA 0.1% GR +Thiamethoxam 25% WG (on farm mixing) 8 kg+400 g 8+100
T8 GA 0.1% GR +Imidacloprid 0.3% GR (on farm mixing) 8 kg+25 kg 8+75
T9 GA 0.1% GR +Bifenthrin 10% EC (on farm mixing) 8 kg+750 ml 8+75
T10 Fipronil 0.6%+Clothianidin 0.75% GR (ready mix) 10 kg 60+75
T11 Fipronil 6%+Thiamethoxam 10% SC (ready mix) 1000 ml 60+100
T12 Fipronil 30%+Imidacloprid 37.5% WG (ready mix) 200 g 60+75
T13 Fipronil 0.3% GR +Bifenthrin 10% EC (on farm mixing) 20 kg+750 ml 60+75
T14 GA 0.1% GR 8 kg 8
T15 Fipronil 0.3% GR 20 g 60
T16 Clothianidin 0.5% GR 15 kg 75
T17 Thiamethoxam 25% WG 400 g 100
T18 Imidacloprid 0.3% GR 25 kg 75
T19 Bifenthrin 10% EC 750 ml 75
T20 UTC (Untreated Control) - -
GA-Gibberellic Acid, WG wettable granule, GR sand coated granule, T1 to T4-novel granular composition (sand coated granule, ready to use). T5 to T9-conventional treatments (on farm mixing), T10 to T12-conventional ready mix formulations, T14 to T19-market available products.

Table 4: Control of stem borer and grain yield in rice crop
Treatment number Stem borer control (%) Grain yield (kg per plot) % increase in grain yield over T20
Dead heart symptoms at 50 DATP White ear symptoms at 100 DATP
Observed Value Calculated Value Colby's ratio Observed Value Calculated Value Colby's ratio
T1 98.2 91.78 1.07 89.2 84.97 1.05 2.21 90.52
T2 95.6 91.26 1.05 87.6 83.76 1.05 2.17 87.36
T3 94.2 90.92 1.04 86.4 82.48 1.05 2.12 83.05
T4 93.6 90.00 1.04 83.8 80.00 1.05 2.06 77.59
T5 75.2 77.47 0.97 62.4 66.44 0.94 1.65 42.53
T6 64.8 67.37 0.96 55.8 57.53 0.97 1.94 67.53
T7 63.4 65.31 0.97 52.6 54.12 0.97 1.89 62.93
T8 61.2 63.97 0.96 48.6 50.51 0.96 1.75 50.57
T9 58.8 60.31 0.98 41.2 43.50 0.95 1.68 45.11
T10 90.2 90.80 0.99 80.8 84.14 0.96 1.97 70.11
T11 89.8 90.22 1.00 78.8 82.87 0.95 1.91 64.94
T12 89.2 89.84 0.99 79.4 81.52 0.97 1.79 54.02
T13 88.4 88.81 1.00 75.6 78.90 0.96 1.71 47.13
T14 10.6 5.2 1.23 5.75
T15 74.8 64.6 1.37 18.39
T16 63.5 55.2 1.43 22.99
T17 61.2 51.6 1.34 15.80
T18 59.7 47.8 1.29 10.92
T19 55.6 40.4 1.29 10.92
T20 0.0 0.0 1.16 0.00
The novel granular formulations (T1 to T4) provides synergistic control of stem borer and also produces higher grain yield as compared to all conventional treatments (T5 to T19). The visual observations of novel granular composition (T1 to T4) shows excellent crop growth in terms of vegetative and reproductive part which produces higher grain yield as compared to all conventional treatments. The novel granular composition (T1 to T4) does not shows any kind of phytotoxicity symptoms.

Experiment 3: Effect of novel granular composition of GA+Plant Health additive+Insecticide on insect control and yield attributing characters in maize crop
Crop : Maize
Location : Lunawada, Gujarat
Plot size : 40 sq.m.
Number of Treatments: Twenty
Replication : Two
Method of Application: Soil application at 10 DAS (days after sowing)-the required quantity of novel granular composition bulked out by mixing with sand and broadcasted manually in the plot, followed by irrigation.
Observation Methods:
Fall Armyworm control (%): Count the number of live larvae per plant. Record the observations from 10 plants per plot, and calculate fall armyworm larval control.
Stem borer control (%): Count the number of healthy and infested (damaged) plants per 1 meter row length. Record the observations from 10 spots per plot. Calculate stem borer incidence (%), and recalculate stem borer control (%).
Table 5: Treatment details
Treatment number Treatment details Formulation per hectare gram active ingredient per hectare
T1 GA 2%+Zinc oxide 10%+Chlorantraniliprole 30% Granule 100 g 2+10+30
T2 GA 1%+Zinc oxide 5%+Cyantraniliprole 30% Granule (Recipe: GZCY 360) 200 g 2+10+60
T3 GA 1%+Zinc oxide 5%+Tetraniliprole 20% Granule 200 g 2+10+40
T4 GA 1%+Zinc oxide 5%+Cyclaniliprole 20% Granule 200 g 2+10+40
T5 GA 0.1% GR+ Zinc oxide 80% WP 2 kg+12.5 g 2+10
T6 GA 0.1% GR+ Chlorantraniliprole 35% WG 2 kg+85.17 g 2+30
T7 GA 0.1% GR+ Cyantraniliprole 10.26% OD 2 kg+600 ml 2+60
T8 GA 0.1% GR+ Tetraniliprole 18.18% SC 2 kg+200 ml 2+40
T9 GA 0.1% GR+ Cyclaniliprole 5% SL 2 kg+800 ml 2+40
T10 Zinc oxide 80% WP+ Chlorantraniliprole 35% WG 12.5 g+85.71 g 12.5+30
T11 Zinc oxide 80% WP+ Cyantraniliprole 10.26% OD 12.5 g+600 ml 12.5+60
T12 Zinc oxide 80% WP+ Tetraniliprole 18.18% SC 12.5 g+200 ml 12.5+40
T13 Zinc oxide 80% WP+ Cyclaniliprole 5% SL 12.5 g+800 ml 12.5+40
T14 GA 0.1% GR 2 kg 2
T15 Zinc oxide 80% WP 12.5 g 12.5
T16 Chlorantraniliprole 35% WG 85.71 g 30
T17 Cyantraniliprole 10.26% (10% w/v) OD 600 ml 60
T18 Tetraniliprole 18.18% (20% w/v) SC 200 ml 40
T19 Cyclaniliprole 5% SL 800 ml 40
T20 UTC (Untreated Control) - -
GA-Gibberellic Acid, WG wettable granule, WP wettable powder, SC suspension concentrate, OD oil dispersion, T1 to T4-novel granular formulation, T5 to T13-conventional treatments (on farm mixing), T14 to T19-market available products.

Table 6: Synergistic control of fall armyworm and stem borer in maize crop
Treatment Number Fall Armyworm control (%) Stem borer control (%)
Observed value Expected value Colby's ratio Observed value Expected value Colby's ratio Synergism (Y/N)
T1 99.2 89.93 1.10 90.4 86.10 1.05 Y
T2 99.8 91.34 1.09 91.2 87.55 1.04 Y
T3 98.4 87.98 1.12 88.6 83.21 1.06 Y
T4 90.6 84.45 1.07 83.2 79.78 1.04 Y
T5 10.8 11.64 0.93 7.8 9.75 0.80 N
T6 88.4 89.26 0.99 80.4 85.31 0.94 N
T7 89.6 90.77 0.99 82.4 86.83 0.95 N
T8 86.2 87.19 0.99 80.8 82.26 0.98 N
T9 82.4 83.42 0.99 75.6 78.63 0.96 N
T10 88.8 89.31 0.99 82.4 85.43 0.96 N
T11 89.6 90.81 0.99 81.4 86.95 0.94 N
T12 86.6 87.24 0.99 80.6 82.40 0.98 N
T13 81.4 83.49 0.97 75.6 78.81 0.96 N
T14 5.8 4.6
T15 6.2 5.4
T16 88.6 84.6
T17 90.2 86.2
T18 86.4 81.4
T19 82.4 77.6
T20 0.0 0.0

The novel granular composition of GA+zinc oxide+insecticides provides synergistic season long control of fall armyworm and stem borer in maize crop. The visual observations of novel granular composition (T1 to T4) shows excellent phyto-tonic effect (dark green color leaves, increase in leaf length, leaf blade width, plant height, number of leaves per plant, stem girth and root biomass) compared to conventional treatments (T5 to T19).

Experiment 4: Effect of novel granular composition of GA+Plant health additive+Insecticide on insect control and yield attributing characters in rice crop
Crop : Rice
Location : Dhamtari, Chattishgarh
Plot size : 33.33 sq.m.
Number of Treatments: 19
Replication : Two
Method of Application: soil application-manual broadcasting of granules at 15 DATP
Observation Methods:
Stem borer control (%): as given in experiment 2.
Leaf folder control (%): Count the number of healthy and damage leaf let per hill. Record the observations from 10 hills per plot. Calculate Leaf folder damage (%) and recalculate leaf folder control (%).
Productive tillers: Count the number of tillers bearing earhead (panicle) per hill. Record the observations from 10 hills per plot.
Grain yield: Record the grain yield (kg) per plot at harvest.
Table 7: Treatment details GA 0.1%+Sulphur 60%+Tetraniliprole 0.5% Granule
Treatment number Treatment details Formulation (kg) per hectare gram active ingredient per hectare
T1 GA 0.1%+Sulphur 60%+Chlorantraniliprole 0.4% Granule 10 kg 10+6000+40=6050
T2 GA 0.1%+Sulphur 60%+Cyantraniliprole 0.6% Granule 10 kg 10+6000+60=6070
T3 GA 0.1%+Sulphur 60%+Tetraniliprole 0.5% Granule (Recipe: GST 606) 10 kg 10+6000+50=6060
T4 GA 0.1%+Sulphur 60%+Flubendiamide 0.7% Granule 10 kg 10+6000+70=6080
T5 GA 0.1%+Sulphur 60%+Cyclaniliprole 0.5% Granule 10 kg 10+6000+50=6060
T6 Sulphur 75%+Chlorantraniliprole 0.4% Granule 10 kg 7500+40=7540
T7 Sulphur 75%+Cyantraniliprole 0.6% Granule 10 kg 7500+60=7560
T8 Sulphur 75%+Tetraniliprole 0.5% Granule 10 kg 7500+50=7550
T9 Sulphur 75%+Flubendiamide 0.7% Granule 10 kg 7500+70=7570
T10 Sulphur 75%+Cyclaniliprole 0.5% Granule 10 kg 7500+50=7550
T11 GA 0.1% GR, 10 kg 10 kg 10
T12 Sulphur 90% Granule 6.67 kg 6000
T13 Sulphur 90% Granule 8.33 kg 7500
T14 Chlorantraniliprole 0.4% GR 10 kg 40
T15 Cyantraniliprole 10.26% (10% w/v) OD, 600 ml 600 ml 60
T16 Tetraniliprole 18.18% (20% w/v) SC, 300 ml 300 ml 50
T17 Flubendiamide 0.7% GR, 10 kg 10 kg 70
T18 Cyclaniliprole 5% SL 1000 ml 50
T19 UTC (Untreated Control) - -
T1 to T5-novel granular composition, T6 to T10-conventional ready mix granular composition, T11 to T18-market available products.

Table 8: Insect-pests control in rice crop and grain yield
Treatment number Stem bore control (%) Leaf folder control (%) Productive tillers per hill Grain yield (kg/plot) Increase (%) in grain yield over T19
T1 96.2 86.2 30.8 2.25 107.06
T2 91.2 81.2 28.4 2.23 104.91
T3 94.6 79.4 27.8 2.20 102.45
T4 93.8 70.2 28.8 2.19 101.84
T5 90.8 71.6 26.8 2.17 100.00
T6 90.2 70.6 21.6 1.94 78.53
T7 82.8 66.8 20.8 1.93 77.30
T8 86.6 62.4 18.4 1.88 73.01
T9 87.2 58.6 19.6 1.77 63.19
T10 80.4 56.2 17.6 1.73 58.90
T11 8.2 5.2 12.6 1.37 26.38
T12 12.6 16.0 12.4 1.35 24.54
T13 14.2 16.8 13.2 1.42 30.67
T14 80.2 70.6 18.2 1.75 61.35
T15 73.6 66.2 16.8 1.70 56.44
T16 70.6 62.4 15.6 1.67 53.99
T17 68.4 60.8 15.8 1.63 49.69
T18 67.6 61.2 14.4 1.59 46.01
T19 0.0 0.0 10.2 1.09 0.00

The novel granular composition (T1 to T5) provides synergistic control of rice stem borer, leaf folder and also produces higher grain yield as compared to conventional granular composition (T6 to T10) and market available products (T11 to T18). The conventional granular compositions (T6 to T10) were used at higher doses (gram active ingredients) in comparison to novel granular composition (T1 to T5).

Experiment 5: Effect of novel granular composition of GA+Plant Health additive+Plant health additive+Insecticide on insect control and yield attributing characters in rice crop
Crop : Rice
Location : Kurud, Chhattishgarh
Plot size : 33.33 sq.m.
Number of Treatments: Sixteen
Replication : Two
Method of Application: Manual broadcasting in soil at 15 DATP
Observation Methods: as given in experiment 2.
Table 9: Treatment details
Treatment number Treatment details with formulations Formulation (kg) per hectare gram active ingredient per hectare
T1 GA 0.05%+Sulphur 60%+Zinc+12%+Fipronil 0.6% Granule (Recipe: GSZF 726) 10 kg 5+6000+1200+60
T2 GA 0.05%+Sulphur 60%+Zinc+12%+Clothianidin 0.75% Granule 10 kg 5+6000+1200+75
T3 GA 0.05%+Sulphur 60%+Zinc+12%+Thiamethoxam 0.75% Granule 10 kg 5+6000+1200+75
T4 GA 0.1% GR +(Sulphur 60%+Zinc 12%) MG 5 kg+10 kg 5+(6000+1200)
T5 GA 0.1% GR +Fipronil 0.6% GR 5 kg+10 kg 5+60
T6 GA 0.1% GR +Clothianidin 0.5% GR 5 kg+15 kg 5+75
T7 GA 0.1% GR +Thiamethoxam 25% WG 5 kg+300 g 5+75
T8 (Sulphur 60%+Zinc 12%) MG +Fipronil 0.6% GR 10 kg+10 kg (6000+1200)+60
T9 (Sulphur 60%+Zinc 12%) MG +Clothianidin 0.5% GR 10 kg+15 kg (6000+1200)+75
T10 (Sulphur 60%+Zinc 12%) MG +Thiamethoxam 25% WG 10 kg+300 g (6000+1200)+75
T11 GA 0.1% GR 10 kg 2
T12 Sulphur 60%+Zinc 12% MG 10 kg (6000+1200)
T13 Fipronil 0.6% GR 10 kg 60
T14 Clothianidin 0.5% GR 15 kg 75
T15 Thiamethoxam 25% WG 300 g 75
T16 UTC (Untreated Control) - -
T1 to T3-novel granular formulation, T4 to T10-on farm mixing of market available product, T11 to T15-market available product.

Table 10: Stem borer control in rice crop
Treatment number Stem borer control Grain yield (kg/plot) Increase grain yield over T16
Dead heart symptoms at 50 DATP White ear symptoms at 100 DATP
Observed Value Calculated value Colby's ratio Observed Value Calculated value Colby's ratio
T1 98.2 76.25 1.29 95.6 73.40 1.30 2.24 116.77
T2 97.8 74.96 1.30 91.2 70.59 1.29 2.23 115.48
T3 96.4 73.04 1.32 88.6 69.60 1.27 2.18 110.65
T4 21.4 19.76 1.08 15.6 17.39 0.90 1.37 32.90
T5 73.4 72.89 1.01 68.8 70.31 0.98 1.87 81.29
T6 72.6 71.42 1.02 65.6 67.18 0.98 1.85 79.35
T7 70.4 69.22 1.02 64.2 66.07 0.97 1.81 74.84
T8 75.4 74.07 1.02 70.2 71.15 0.99 1.97 90.97
T9 73.2 72.67 1.01 67.4 68.10 0.99 1.94 87.74
T10 71.2 70.57 1.01 65.6 67.03 0.98 1.89 83.23
T11 8.4 7.8 1.28 23.87
T12 12.4 10.4 1.32 27.74
T13 70.4 67.8 1.71 65.16
T14 68.8 64.4 1.66 60.65
T15 66.4 63.2 1.61 55.48
T16 0.0 0.0 1.03 0.00

All the novel granular formulation (T1 to T3) provides synergistic control of rice stem borer and also yielded higher grain.

Experiment 6: Effect of novel granular composition of GA+Plant Health additive+Insecticide on insect control and yield attributing characters in sugarcane crop
Crop : Sugarcane
Location : Karnal, Haryana
Plot size : 50 sq.m.
Number of Treatments: Twenty eight
Replication : Two
Method of Application: At the time of cane planting, the required quantity of novel granular composition broadcasted manually in the open furrow over the sugarcane setts then covered with soil.
Observation Methods:
Early shoot borer (Chilo infuscatellus) incidence (%):
Fifty shoots per plot were selected randomly and presence of characteristic “dead heart”
(damaged shoots) were recorded to calculate per cent shoot damage by early shoot borer at 45
(DAP) days after planting.

Early shoot borer (ESB) control calculated by below formula,

Early shoot borer control (%) data used to check the synergism by applying Colby’s formula given above.
Shoot count: Count the number of shoots/tillers from 1 mrl (meter row length) from randomly selected 5 spot per plot at 60 days after planting.
The percent increase in shoot over untreated control were calculated by below formula.

Table 11: Treatment details
Treatment number Treatment details Formulation per hectare gram active ingredient per hectare
T1 (GA 0.05%+Zinc 10%+Sulphur 50%+Chlorantraniliprole 0.4%) Granule (Recipe:GSZC 604) 10 kg 5+1000+5000+40
T2 (GA 0.05%+Zinc 10%+Sulphur 50%+Cyantraniliprole 0.6%) Granule 10 kg 5+1000+5000+60
T3 (GA 0.05%+Zinc 10%+Sulphur 50%+Tetraniliprole 0.6%) Granule 10 kg 5+1000+5000+60
T4 (GA 0.05%+Zinc 10%+Sulphur 50%+Flubendiamide 0.7%) Granule 10 kg 5+1000+5000+70
T5 GA 0.1% GR 5 kg 5
T6 (Zinc 10%+Sulphur 50% Granule) MG 10 kg (1000+5000)
T7 Chlorantraniliprole 0.4% GR 10 kg 40
T8 Cyantraniliprole 10.26% (10% w/v) OD 600 ml 60
T9 Tetraniliprole 18.18% (20% w/v) SC 300 ml 60
T10 Flubendiamide 0.7% GR 10 kg 70
T11 UTC (Untreated Control) - -
T1 to T4-novel granular formulation, T5 to T10- market available products.
Table 12: Early shoot borer control in sugarcane
Treatment number Early shoot borer control (%) Number of shoots per meter row length Increase(%) in shoots over T11
Observed Value Calculated value Colby's ratio
T1 98.2 81.96 1.20 72.8 116.67
T2 96.4 79.29 1.22 70.6 110.12
T3 94.8 77.62 1.22 69.6 107.14
T4 93.6 75.28 1.24 68.4 103.57
T5 6.8 41.4 23.21
T6 10.4 45.2 34.52
T7 78.4 58.4 73.81
T8 75.2 56.4 67.86
T9 73.2 53.8 60.12
T10 70.4 52.6 56.55
T11 0.0 33.6 0.00

The novel granular formulation (T1 to T4) provides synergistic control of early shoot borer in sugarcane crop and also produces higher number of shoot per 1 meter row length, which directly contributing to the cane yield.

Experiment 7: Effect of novel granular composition of GA+Plant Health additive+Plant health additive+Insecticide on insect control and yield in cumin crop
Crop : Cumin
Location : Tharad, Gujarat
Plot size : 50 sq.m.
Number of Treatments: 11
Replication : Three
Application Time : 15 days after sowing
Method of Application: The required quantity of novel granular composition broadcasted manually in the plot followed by irrigation.
Observation Methods:
Larval control (Helicoverpa armigera, Spodptera exigua): Count the number of live larvae from 1 sq.m. area at 30 and 60 days after sowing. Calculate larval control (%) as below;

Table 13: Treatment details
Treatment number Treatment details Formulation per hectare gram active ingredient per hectare
T1 (GA 0.1%+Triacontanol 0.1%+Zinc 2%+Chlorantraniliprole 0.4%) GR (Recipe: GTZC 260) 10 kg 10+10+200+40
T2 (GA 0.1%+Triacontanol 0.1%+Zinc 2%+Cyantraniliprole 0.6%) GR 10 kg 10+10+200+60
T3 (GA 0.1%+Triacontanol 0.1%+Zinc 2%+Tetraniliprole 0.6%) GR 10 kg 10+10+200+60
T4 (GA 0.1%+Triacontanol 0.1%+Zinc 2%+Cyclaniliprole 0.6%) GR 10 kg 10+10+200+60
T5 (GA 0.1%+Triacontanol 0.1%) GR 10 kg 10+10
T6 Zinc lactate gluconate 12% WP 1666.67 g 200
T7 Chlorantraniliprole 0.4% GR 10 kg 40
T8 Cyantraniliprole 10.26% (10% w/v) OD 600 ml 60
T9 Tetraniliprole 18.18% (20% w/v) SC 300 ml 60
T10 Cyclaniliprole 4.55% (5% w/v) SL 1200 ml 60
T11 UTC (Untreated Control) - -
T1 to T4-novel granular formulation (sand coated, ready to use), T5 to T10- market available products
Table 14: Larval control and yield in cumin crop
Treatment number Larval control (%) Yield (kg per plot) Increase in Yield over T11
30 DAS 60 DAS
Observed Value Calculated Value Colby's ratio Observed Value Expected value Colby's ratio
T1 100 92.31 1.08 92.8 83.21 1.12 4.58 131.3
T2 100 90.87 1.10 89.6 81.68 1.10 4.52 128.3
T3 100 89.91 1.11 88.4 79.14 1.12 4.46 125.3
T4 100 89.11 1.12 86.4 78.12 1.11 4.36 120.2
T5 12.4 9.6 3.2 61.6
T6 8.6 6.2 2.86 44.4
T7 90.4 80.2 3.68 85.9
T8 88.6 78.4 3.52 77.8
T9 87.4 75.4 3.34 68.7
T10 86.4 74.2 3.12 57.6
T11 0.0 0.0 1.98 0.0

All the novel granular formulation (T1 to T4) provide synergistic residual control of larvae and produces higher cumin yield.

Experiment 8: Effect of novel granular composition of GA+Insecticide on insect control and yield in marigold flower
Crop : Marigold
Location : Umreth, Gujarat
Plot size : 50 sq.m.
Number of Treatments: 8
Replication : Three
Method of Application: At 30 DATP (days after transplanting), the required quantity of novel granular composition were bulked out by mixing with farm soil and broadcasted manually in the plot followed by irrigation.
Observation Methods:
Larval control(%): Count the number of live larvae per plant. Record the observations from 10 plants per plot and calculate larval control (%).
Flower count: Count the number of flowers from 10 plants per plot.
Table 15: Larval control and flower count in marigold
Treatment details with formulations and gram active per hectare Larval control (%) Number of flowers per plant Increase(%) in flower over T8
Observed control Expected control Colby's ratio Synergism
T1-GA 2.32%+Chlorantraniliprole 35% Granule, 86 g (2+30 gai/h) (Recipe: GAC 373) 94.6 90.53 1.04 Yes 28.4 94.5
T2-GA 1.17%+Cyantraniliprole 35% Granule, 170 g (2+60 gai/h) 92.4 88.12 1.05 Yes 27.2 86.3
T3-GA 1.14%+Tetraniliprole 35% Granule, 144 g (2+50 gai/h) 90.6 86.45 1.05 Yes 26.4 80.8
T4-GA 40% WSG, 5 g (2 gai/h) 7.2 16.4 12.3
T5-Chlorantraniliprole 35% WG, 86 g (30 gai/h) 89.8 23.8 63.0
T6-Cyantraniliprole 10.26% (10% w/v) OD, 600 ml (60 gai/h) 87.2 23.2 58.9
T7-Tetraniliprole 18.18% (20% w/v) SC, 250 ml (50 gai/h) 85.4 22.4 53.4
T8-Untreated Check (UTC) 0.00 14.6 0.0
T1 to T3-novel granular composition, T4 to T7-market available products.
The novel granular composition (T1, T2, T3) provides synergistic control of Spodoptera litura larvae and produces higher number of flowers.

Experiment 9: Effect of GA+Insecticide+Insecticide on Thrips control in onion crop
Crop : Onion
Target Pests : Thrips
Application method : The required quantity of novel granular composition bulked out by mixing with sand and broadcasted manually in the plot followed by irrigation.
Thrips control (%): Count the number of live thrips per plant. Record the observations from 10 plants per plot.

Yield : Record the observations on bulb yield in kg per 100 sq.m. area.
Table 16: Treatment details
Treatment number Treatment details Formulation per hectare gram active ingredient per hectare
T1 GA 0.3%+Flonicamid 12%+Fipronil 12% Granule 500 g 1.5+60+60
T2 GA 0.3%+Flonicamid 12%+Tolfenpyrad 15% Granule (Recipe: GFT 273) 500 g 1.5+60+75
T3 GA 0.15%+Flonicamid 6%+Diafenthiuron 20% Granule 1000 g 1.5+60+200
T4 GA 0.15%+Flonicamid 6%+Profenofos 25% Granule 1000 g 1.5+60+250
T5 GA 0.75%+Flonicamid 30%+Abamectin 3.75% Granule 200 g 1.5+60+7.5
T6 GA 40% WSG 3.75 g 1.5
T7 Flonicamid 50% WG 120 g 60
T8 Fipronil 80% WG 75 g 60
T9 Tolfenpyrad 15% EC 500 ml 75
T10 Diafenthiuron 50% WP 400 g 200
T11 Profenofos 50% EC 500 ml 250
T12 Abamectin 1.9% EC 394.73 ml 7.5
T13 UTC (Untreated Control) - -
T1 to T5-novel granular composition, T6 to T12-market available products
Table 17: control of thrips in onion crop
Treatment number Thrips control (%) Bulb yield (kg) Increase (%) in yield over T13
Observed Value Calculated value Colby's ratio
T1 90.8 78.37 1.16 4.10 89.81
T2 98.6 86.46 1.14 4.28 98.15
T3 88.4 78.20 1.13 3.90 80.56
T4 91.2 79.22 1.15 3.98 84.26
T5 93.4 80.67 1.16 4.06 87.96
T6 6.2 3.46 60.19
T7 54.6 2.96 37.04
T8 49.2 3.16 46.30
T9 68.2 3.28 51.85
T10 48.8 2.64 22.22
T11 51.2 2.58 19.44
T12 54.6 3.04 40.74
T13 0.0 2.16 0.00

All the novel granular composition (T1 to T5) provides excellent synergistic control of thrips and also yielded higher bulb.

Experiment 10: Effect of GA+Fungicide+Fungicide on damping off disease in tobacco nursery
Crop : Tobacco (Nursery)
Target Disease : Damping Off disease
Application method : The required quantity of novel granular composition bulked out by mixing with sand and broadcasted manually in the plot followed by irrigation.
Damping off disease control (%): Evaluate visually the plot area infected/damaged due to damping off disease. Plot size was 4 sq.m. (2 m x 2m). Count the number of healthy seedlings (ready to transplant) per plot area.
Table 18: Treatment details
Treatment number Treatment details Formulation (gram/hectare gram active ingredient per hectare
T1 GA 0.2%+Dimethomorph 15%+Pyraclostrobin 10% Granule 1500 2+150+100
T2 GA 0.133%+Dimethomorph 10%+Metiram 40% Granule 1500 2+150+600
T3 GA 0.133%+Dimethomorph 10%+Mancozeb 40% Granule 1500 2+150+600
T4 GA 0.133%+Dimethomorph 10%+Chlorothalonil 40% Granule 1500 2+150+600
T5 GA 0.133%+Dimethomorph 10%+Propineb 40% Granule 1500 2+150+600
T6 GA 0.4%+Cyazofamid 10%+Dimethomorph 50% Granule 500 2+50+250
T7 GA 0.2%+Cyazofamid 5.3%+Mancozeb 69.7% Granule 1000 2+53+697
T8 GA 0.2%+Cyazofamid 5.3%+Metiram 69.7% Granule 1000 2+53+697
T9 Dimethomorph 12%+Pyraclostrobin 6.66% WG 1500 180+100
T10 Dimethomorph 9%+Metiram 44% WG 2000 180+880
T11 Dimethomorph 9%+Mancozeb 44% WG 2000 180+880
T12 Dimethomorph 9%+Chlorothalonil 44% WG 2000 180+880
T13 Dimethomorph 9%+Propineb 44% WG 2000 180+880
T14 Cyazofamid 10%+Dimethomorph 30% SC 1000 100+300
T15 Cyazofamid 5.3%+Mancozeb 69.7% WG 1250 66.25+871.25
T16 Cyazofamid 5.3%+Metiram 69.7% WG 1250 66.25+871.25
T17 GA 0.1% GR 2
T18 Dimethomorph 50% WP 250
T19 Cyazofamid 34.5% (40% w/v) SC 53
T20 Pyraclostrobin 20% WG 75
T21 Metiram 70% WG 1000
T22 Mancozeb 70% WG 1000
T23 Chlorothalonil 75% WP 750
T24 Propineb 70% WP 1000
T25 UTC (Untreated Control) - -
T1 to T8-novel granular composition, T9 to T16-conventional ready mix formulations, T17 to T24-market available products.

Table 19: Damping off disease control and healthy seedlings
Treatment number Plot area (%) infected with disease Disease control (%) No. of Healthy seedlings from 0.25 sq.m area Increase (%) in healthy seedlings over T25
Healthy plot area (Control Observed) Control Expected Colby's ratio
T1 1.4 98.6 95.38 1.03 375 101.61
T2 1.7 98.3 93.89 1.05 370 98.92
T3 1.8 98.2 93.63 1.05 366 96.77
T4 1.6 98.4 93.45 1.05 358 92.47
T5 1.9 98.1 93.68 1.05 342 83.87
T6 1.2 98.8 97.54 1.01 395 112.37
T7 1.6 98.4 93.36 1.05 381 104.84
T8 1.3 98.7 93.62 1.05 378 103.23
T9 2.4 97.6 308 65.59
T10 2.8 97.2 304 63.44
T11 3.6 96.4 298 60.22
T12 3.8 96.2 296 59.14
T13 3.6 96.4 297 59.68
T14 2.4 97.6 326 75.27
T15 2.2 97.8 302 62.37
T16 2.0 98.0 310 66.67
T17 68.2 31.8 198 6.45
T18 18.6 81.4 284 52.69
T19 19.4 80.6 298 60.22
T20 36.4 63.6 274 47.31
T21 48.2 51.8 246 32.26
T22 50.2 49.8 238 27.96
T23 51.6 48.4 247 32.80
T24 49.8 50.2 228 22.58
T25 0 100.0 186 0.00

The novel granular formulations (T1 to T8) provides excellent control of damping off disease in tobacco nursery and also produces higher number of healthy transplantable seedlings as compared to all conventional ready mix formulations (T9 to T16) and market available products (T17 to T24).

Experiment 11: Effect of GA+Fungicide+Fungicide on white rot disease in groundnut
Crop : Groundnut
Target Disease : White rot (Sclerotium rolfsii)
Application method : The required quantity of novel granular composition bulked out by mixing with sand and broadcasted manually in the plot.
White rot disease incidence (%): Count the number of healthy and diseased plant per 1 sq.m. area. Calculate disease incidence (%).
Number of pods per plant: Count the number of pods per plant. Record the observations from 10 plants per plot.

Table 20: Treatment details
Treatment number Treatment details Formulation (gram/hectare) gram active ingredient per hectare
T1 GA 0.133%+Sulphur 60%+Pyraclostrobin 5% Granule 1500 2+900+75
T2 GA 0.133%+Sulphur 60%+Azoxystrobin 5% Granule 1500 2+900+75
T3 GA 0.133%+Sulphur 60%+Trifloxystrobin 5% Granule 1500 2+900+75
T4 GA 0.133%+Sulphur 60%+Picoxystrobin 5% Granule 1500 2+900+75
T5 GA 0.2%+Sulphur 60%+Hexaconazole 4% Granule 1000 2+600+40
T6 GA 0.2%+Sulphur 60%+Difenoconazole 5% Granule 1000 2+600+50
T7 GA 0.2%+Sulphur 60%+Epoxiconazole 7.5% Granule 1000 2+600+75
T8 GA 0.2%+Sulphur 60%+Prothioconazole 7.5% Granule 1000 2+600+75
T9 GA 0.2%+Sulphur 60%+Propiconazole 7.5% Granule 1000 2+600+75
T10 GA 0.2%+Sulphur 60%+Fluxapyroxad 5% Granule 1000 2+600+50
T11 Sulphur 60%+Pyraclostrobin 5% Granule 1500 900+75
T12 Sulphur 60%+Azoxystrobin 5% Granule 1500 900+75
T13 Sulphur 60%+Trifloxystrobin 5% Granule 1500 900+75
T14 Sulphur 60%+Picoxystrobin 5% Granule 1500 900+75
T15 Sulphur 60%+Hexaconazole 4% Granule 1000 600+40
T16 Sulphur 60%+Difenoconazole 5% Granule 1000 600+50
T17 Sulphur 60%+Epoxiconazole 7.5% Granule 1000 600+75
T18 Sulphur 60%+Prothioconazole 7.5% Granule 1000 600+75
T19 Sulphur 60%+Propiconazole 7.5% Granule 1000 600+75
T20 Sulphur 60%+Fluxapyroxad 5% Granule 1000 600+50
T21 GA 0.1% GR 2000 2
T22 Sulphur 80% WG 750 600
T23 Sulphur 80% WG 1125 900
T24 Pyraclostrobin 20% WG 375 75
T25 Azoxystrobin 23% (25% w/v) SC 300 75
T26 Trifloxystrobin 25% WG 300 75
T27 Picoxystrobin 25% WG 300 75
T28 Hexaconazole 80% WG 50 40
T29 Difenoconazole 25% EC 200 50
T30 Epoxiconazole 25.9% EC 300 75
T31 Prothioconazole 25% EC 300 75
T32 Propiconazole 25% EC 300 75
T33 Fluxapyroxad 33.3% SC 150.2 50
T34 UTC (Untreated Control) - -
T1 to T10-novel granular formulation, T11 to T20-conventional ready mix granular formulation, T21 to T33-market available product (except T31).

Table 21: White rot disease incidence and pod count in groundnut
Treatment number Incidence (%) white rot Average number of healthy pods per plant Increase (%) in pods over T34 Increase (%) in pods over
T1 1.2 36.5 185.16 52.90 over T11
T2 1.6 37.2 190.63 49.69 over T12
T3 0.8 38.3 199.22 44.07 over T13
T4 1.4 37.3 191.41 54.09 over T14
T5 1.8 31.2 143.75 75.24 over T15
T6 2.2 33.4 160.94 67.48 over T16
T7 1.9 32.8 156.25 80.18 over T17
T8 1.8 33.5 161.72 60.47 over T18
T9 2.0 35.4 176.56 63.77 over T19
T10 1.6 36.2 182.81 56.00 over T20
T11 1.8 28.3 121.09
T12 2.4 29.1 127.34
T13 1.5 30.5 138.28
T14 2.6 28.7 124.22
T15 2.7 23.3 82.03
T16 3.0 25.1 96.09
T17 2.9 23.9 86.72
T18 2.8 25.7 100.78
T19 3.2 26.6 107.81
T20 2.4 27.8 117.19
T21 36.2 13.9 8.59
T22 20.2 15.3 19.53
T23 16.8 16.8 31.25
T24 6.8 22.7 77.34
T25 5.6 24.1 88.28
T26 6.2 21.6 68.75
T27 5.8 17.2 34.38
T28 10.8 18.9 47.66
T29 9.6 17.6 37.50
T30 8.8 19.3 50.78
T31 9.4 20.4 59.38
T32 9.8 21.5 67.97
T33 8.4 22.5 75.78
T34 40.6 12.8 0.00

The lowest white rot disease incidence and higher number of pods per plant has been observed with treatment of novel granular composition (T1 to T10) as compared to conventional ready mix granular composition (T11 to T20) and market available products.

,CLAIMS:CLAIMS
We claim;
[CLAIM 1]. A synergistic granular agrochmemical composition comprising:
a. gibberellic acid present in an amount of 0.001 to 10%w/w;
b. one or more of compound selected from an insecticide; a fungicides; a plant health additive; or combination thereof present in an amount of 0.01 to 90%w/w;
c. one or more inactive formulation excipients.

[CLAIM 2]. The synergistic granular agrochmemical composition as claimed in claim 1, wherein an insecticide is selected from carbaryl, carbofuran, carbosulfan, methomyl, oxamyl, pirimicarb, thiodicarb,,acephate, cadusafos, chlorpyrifos, chlorpyrifos-methyl, demeton-S-methyl, dimethoate, ethion, fenamiphos, fenitrothion, fenthion, fosthiazate, methamidophos, monocrotophos, oxydemeton-methyl, parathion, parathion-methyl, phenthoate, phorate, phosalone, phosphamidon, profenofos, quinalphos, triazophos, ethiprole, fipronil, flufiprole, nicofluprole, pyrafluprole, pyriprole,,bifenthrin, cyfluthrin, beta-cyfluthrin, cyhalothrin, lambda-cyhalothrin, gamma-cyhalothrin, cypermethrin, alpha-cypermethrin, beta-cypermethrin, theta-cypermethrin, zeta-cypermethrin, cyphenothrin, deltamethrin, fenpropathrin, fenvalerate, tau-fluvalinate, permethrin, phenothrin, prallethrin, profluthrin, pyrethrin (pyrethrum), acetamiprid, clothianidin, dinotefuran, imidacloprid, nitenpyram, thiacloprid, thiamethoxam, flupyrimin, cycloxaprid, paichongding, guadipyr, cycloxylidin; sulfoximines-sulfoxaflor; butenolides- flupyradifurone; mesoionics- triflumezopyrim, dichloromezotiaz, fenmezoditiaz, spinosad and spinetoram, avermectins-abamectin, emamectin benzoate, ivermectin, lepimectin; milbemycins- milbemectin, hydroprene, kinoprene, methoprene, fenoxycarb, pyriproxyfen, pymetrozine, pyrifluquinazon; afidopyropen, flonicamid, clofentezine, hexythiazox, diflovidazin, etoxazole, Bacillus thuringiensis and insecticidal proteins, diafenthiuron, azocyclotin, cyhexatin, fenbutatin oxide, propargite, tetradifon, chlorfenapyr, DNOC, sulfluramid, bensultap, monosultap, cartap hydrochloride, thiocyclam, thiocyclam hydrogen oxalate, thiocyclam hydrochloride, thiosultap sodium, benzoylureas-bistrifluron, chlorfluazuron, diflubenzuron, flucycloxuron, flufenoxuron, hexaflumuron, lufenuron, novaluron, noviflumuron, teflubenzuron, triflumuron, buprofezin, cyromazine, diacylhydrazines- methoxyfenozide, tebufenozide, halofenozide, fufenozide, chromafenozide. amitraz, fenazaquin, fenpyroximate, pyrimidifen, pyridaben, tebufenpyrad, tolfenpyrad, flufenerim, rotenone, cyenopyrafen, cyflumetofen, pyflubumidemm, hydramethylnon, acequinocyl, flometoquin, fluacrypyrim, pyriminostrobin, bifenazate, indoxacarb and metaflumizone, tetronic and tetramic acid derivatives-spirodiclofen, spiromesifen, spirotetramat, spidoxamat, spiropidion, chlorantraniliprole, cyantraniliprole, cyclaniliprole, tetraniliprole, tetrachlorantraniliprole, tyclopyrazoflor, cyhalodiamide, flubendiamide, fluchlordiniliprole, broflanilide, cyproflanilide, fluxametamide, isocycloseram, afoxolaner, esafoxolaner, fluralaner, lotilaner, sarolaner, granuloviruses and nucleopolyhedrosis viruses, benzpyrimoxan, pyridalyl, oxazosulfyl, dimpropyridaz, acaricidal compounds-fluhexafon, cyetpyrafen, flupentiofenox, acyonapyr; nematicidal compounds-cyclobutrifluram, fluazaindolizine, tioxazafen.

[CLAIM 3]. The synergistic granular agrochmemical composition as claimed in claim 1, wherein a fungicide is selected from Acylalanines-benalaxyl, benalaxyl-M (=kiralaxyl), furalaxyl, metalasxyl, metalaxyl-M (=mefenoxam)), butyrolactones(ofurace),oxazolidinones (oxadixyl), hydroxy-(2-amino-) pyrimidines; bupirimate, dimethirimol, ethirimol, heteroaromatics; isothiazolones-octhilinone, isoxazoles-hymexazole; carboxylic acids(A4)-oxolinic acid; Other-5-fluorocytosine, 5- fluoro-2-(p-tolylmethoxy)pyrimidin-4-amine,5-fluoro-2-(4-fluorophenyl methoxy)pyrimidin-4amine, benomyl, carbendazim, fuberidazole, thiabendazole; thiophanate, thiophanate-methyl; diethofencarb; zoxamide; ethaboxam; pencycuron; fluopicolide, flufenoxadiazam, fluopimomide; phenamacril; metrafenone; pyriofenone, diflumetorim; tolfenpyrad; fenazaquin; benodanil, flutolanil, mepronil; isofetamid; pyridinyl- fluopyram; fenfuran; carboxin, oxycarboxin, thifluzamide; benzovindiflupyr, bixafen, fluindapyr, fluxapyroxad, furametpyr, isopyrazam, penflufen, penthiopyrad, sedaxane, flubeneteram, pyrapropoyne, inpyrfluxam, isoflucypram, pydiflumetofen; boscalid, pyraziflumid; benzyl carbamates-pyribencarb; dihydro dioxazines-fluoxastrobin; imidazolinones-fenamidone; methoxy acetamide; mandestrobin; methoxy acrylates-azoxystrobin, coumoxystrobin, enoxastrobin, flufenoxystrobin, picoxystrobin, pyraoxystrobin; methoxy carbamates-pyraclostrobin, pyrametostrobin, triclopyricarb; oxazolidine diones-famoxadone; oximino acetamides-dimoxystrobin, fenamistrobin, metominostrobin, orysastrobin; oximino acetates-kresoxim methyl, trifloxystrobincyano imidazole-cyazofamid; sulfamoyl triazole-amisulbrom; picolinamides-fenpicoxamid, florylpicoxamid, metarylpicoxamid; tetrazolinones-metyltetraprole; binapacryl, meptyldinocap, dinocap, fluazinam, inhibitors of oxidative phosphorylation, fentin acetate, fentin chloride, fentin hydroxide, silthiofam, Quinone outside Inhibitors, ametoctradin, cyprodinil, mepanipyrim, pyrimethanil, blasticidin-S, kasugamycin, streptomycin, oxytetracycline, quinoxyfen, proquinazid, fenpiclonil, fludioxonil, chlozolinate, dimethachlone, iprodione, procymidone, vinclozolin, isoprothiolane, edifenphos, iprobenfos (IBP), pyrazophos, biphenyl, chloroneb, dicloran, quintozene, tecnazene, tolcofos methyl, etridiazole, carbamates (F4)-iodocarb, propamocarb, prothiocarb, extract from Melaleuca arternifolia (tea tree), plant oils (mixtures); eugenol, geraniol, thymol, natamycin (pimaricin), oxathiapipronil, fluoxapipronil, Fluoxapiprolin-s, imazalil, oxpoconazole, pefurazoate, procloraz, triflumizole, piperazines-triforine, pyridines-pyrifenox, pyrisoxazole, pyrimidines-fenarimo, naurimol, triazoles-azaconazole, bitertanol, bromuconazole, cyproconazole, difenoconazole, diniconazole, epoxiconazole, etaconazole, fenbuconazole, fluquinconazole, flusilazole, frutriafol, hexaconazole, imibenconazole, ipconazole, mefentrifluconazole, metconazole, myclobutanil, penconazole, propiconazole, prothioconazole, simconazole, tebuconazole, tetraconazole, tiradimefon, tiradimenol, triticonazole, fluoxytioconazole, aldimoprh, dedomorph, tridemorph, fenpropimorph, fenpropidin, piperalin, spiroxamine, fenpyrazamine, fenhexamid, naftifine, terbinafine, pyributicarb, polyoxin, dimethomorph, flumorph, pyrimorph, mandipropamid, benthiavalicard, iprovalicarb, alifenalate, fthalide, pyrrolo quinolinone-pyroquilon, triazolobenzothiazole-tricyclazole, diclycymet, carpropamid, fenoxanil, tolprocarb, acibenzolar-S-methyl, probenazole, tiadinil, isotianil, laminarin, extract from Reynoutria sachalinensis (giant knowweed), Bacillus mycoides isolate J, cell awall of Saccharomyces erevisiae strain LAS117, fosetyl-AL, phosphoric acid and salts, cymoxanil, teclofthalam, benzotirazines-triazoxide, benzene-sulfonamides-fluslfamide, pyridazinones-diclomezine, cyflufenamid, guanindines-dodine, cyano methylene thiazolidines-flutianil, pyrimidinone hydrazones-ferimzone, flumetylsulforim, tebufloquin, picarbutrazox, validamycin, copper hydroxide, copper oxychloride, copper (II) sulphate, Bordeaux mixture, copper salicylate, cuprous oxide, sulphur, dithiocarbamates and relatives-ferbam, mancozeb, maneb, metiram, propineb, thiram, zinc thiazole, zineb, ziram, phthalimides-captan, captafol, folpet, chloronitriles (phthalonitriles)-chlorothalonil, sulfamides-dichlofluanid, tolylfluanid, bis guanidines-guazatine, iminoctadine, triazines-anilazine, quinones (anthraquinones)-dithianon, quinoxalines-chinomethionat/ quinomethionate, maleimide-fluoroimide, thiocarbamate-methasulfocarb, polypeptide (lectin)-extract from the cotyledons of lupine plantlets (“BLAD”), Plant extract-Phenols, Sesquiterpenes, Triterpenoids, Coumarins, microbial (living microbes or extract metabilites-Trichoderma atroviride strain SC1, Trichoderma atroviride strain I-1237, Trichoderma atroviride strain LU132, Trichoderma asperellum strain T34, Gliocladium catenulatum strain J1446 , Clonostachys rosea strain CR-7 , Bacillus amyloliquefaciens strain QST713, strain FZB24, strain MBI600, strain D747, strain F727, Bacillus subtilis strain AFS032321, Pseudomonas chlororaphis strain AFS009, Streptomyces griseovirides strain K61, Streptomyces lydicus strain WYEC108, Ipflufenoquin, Pyridachlometyl, quinofumelin, dichlobentiazox, aminopyrifen, dipymetitrone, seboctylamine (bactericide), chloroinconazide (virucide).

[CLAIM 4]. The synergistic granular agrochmemical composition as claimed in claim 1, wherein plant health additive is selected ftom humic acid (salts), fulvic acid (salts), amino acids- alanine, arginine, aspartic acid, cysteine, glutamic acid, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, proline, serine, threonine, tryptophan, tyrosine, valine or mixture thereof, protein hydrolysates, peptides, organic acid, acetyl thioproline, thiazolidine carboxylic acid, jasmonic acid, methyl jasmonate, chitosan, chitin, alginate, cellulose, starch, cyclodextrin, probenazole, acibenzolar-s-methyl, seaweed extract (Ascophyllum nodosum), polyamines, silicic acid (salts)-orthosilicic acid (H4Si04), salicylic acid, lactic acid, phenyl lactic acid, fumaric acid, acibenzolar-s-methyl, nitrobenzene, (Homo)brassinolide, forchlorfenuron, triacontanol, nitrophenolate (sodium para-nitrophenolate, ortho-nitrophenolate, sodium-5-nitroguaiacolate or mixture thereof, Indole acetic acid, Indole butyric acid, alpha-naphthyl acetic acid; kinetin, zeatin, 6-benzylaminopurine, 6-benzyladenine, dipheylurea, thidiazuron, anisiflupurin; aviglycine, prohexadione, prohexadione calcium, trinexapac, trinexapac-ethyl, aminoethoxyvinylglycine (AVG); abscisic acid, chlorpropham, flumetralin, maleic hydrazide, mepiquat, mepiquat chloride, mepiquat pentaborate; chlormequat, chlormequat chloride, paclobutrazol, uniconazole-P, Rhizobium spp., Azotobacter spp., Azospirillum spp., Acetobacter spp., Bacillus megaterium var. phosphaticum, Bacillus polymyxa, Bacillus licheniformis, Frateuria aurantia, Thiobacillus thiooxidans, VAM (Vesicular Arbuscular Mycorrhiza) (Acaulospora spp., Gigaspora spp., Sclerocystis spp., Scutellospora spp., Glomus spp. Etc.), Acinetobacter calcoaceticus, Bacillus subtilis, Bacillus thuringiensis var. kurstaki, Pseudomonas fluorescens, Beauveria bassina, Metarrhizium anisopliae, Varticillium lecanii, Trichoderma viride, Trichoderma harzianum, Paecilomyces lilacinus, Trichoderma spp. etc. or mixture thereof, zinc (zinc sulphate heptahydrate, zinc sulphate mono hydrate, Zn-EDTA, zinc oxide, zinc lactate gluconate, zinc polyflavonoid), ferrous sulphate, copper sulphate, Manganese sulphate, boron (borax-sodium tetraborate, boric acid (H3BO3), di-sodium octa borate tetra hydrate (Na2B8O13.4H2O), di-sodium tetra borate penta hydrate, anhydrous borax, ) and sulphur (elemental sulphur, bentonite sulphur, boronated sulphur or a sulphate and thiosulphate salt) or mixture thereof.

[CLAIM 5]. The synergistic granular agrochmemical composition as claimed in claim 1, wherein formulation for the said agrochemical composition is selected from Granule (GR), Soil Applied Granules (SAG), Controlled release granules (CR) either slow release granule or fast release granules.

[CLAIM 6]. The synergistic granular agrochmemical composition as claimed in claim 1, wherein the preferred combinations of active ingredients for granule formulation in said composition comprises:
a. GA2.32%+Chlorantraniliprole35%;
b. GA1.17%+Cyantraniliprole35%;
c. GA1.4%+Tetraniliprole35%;
d. GA0.1%+Zinc12%+Sulphur60%;
e. GA0.1%+Zinc12%+Triacontanol0.1%;
f. GA2%+Zinc10%+Chlorantraniliprole30%;
g. GA1%+Zinc5%+Cyantraniliprole30%;
h. GA1%+Zinc5%+Tetraniliprole20%;
i. GA1%+Zinc5%+Cyclaniliprole20%;
j. GA0.1%+Sulphur60%+Chlorantraniliprole0.4%;
k. GA0.1%+Sulphur60%+Cyantraniliprole0.6%;
l. GA0.1%+Sulphur60%+Tetraniliprole0.5%;
m. GA0.1%+Sulphur60%+Flubendiamide0.7%;
n. GA0.1%+Sulphur60%+Cyclaniliprole0.5%;
o. GA0.3%+Flonicamid12%+Fipronil12%;
p. GA0.3%+Flonicamid12%+Tolfenpyrad15%;
q. GA0.15%+Flonicamid6%+Diafenthiuron20%;
r. GA0.15%+Flonicamid 6%+Profenofos25%;
s. GA0.75%+Flonicamid 30%+Abamectin3.75%;
t. GA0.05%+Zinc10%+Sulphur50%+Chlorantraniliprole0.4%;
u. GA0.05%+Zinc10%+Sulphur50%+Cyantraniliprole0.6%;
v. GA0.05%+Zinc10%+Sulphur50%+Tetraniliprole0.6%;
w. GA0.05%+Zinc10%+Sulphur50%+Flubendiamide0.7%;
x. GA0.05%+Zinc12%+Sulphur60%+Clothianidin0.75%;
y. GA0.05%+Zinc12%+Sulphur60%+Thiamethoxam0.75%;
z. GA0.05%+Zinc12%+Sulphur60%+Fipronil0.6%;
aa. GA 0.2%+Dimethomorph 15%+Pyraclostrobin 10%;
bb. GA 0.133%+Dimethomorph 10%+Metiram 40%;
cc. GA 0.133%+Dimethomorph 10%+Mancozeb 40%;
dd. GA 0.133%+Dimethomorph 10%+Chlorothalonil 40%;
ee. GA 0.133%+Dimethomorph 10%+Propineb 40%;
ff. GA 0.4%+Cyazofamid 10%+Dimethomorph 50%;
gg. GA 0.2%+Cyazofamid 5.3%+Mancozeb 69.7%;
hh. GA 0.2%+Cyazofamid 5.3%+Metiram 69.7%;
ii. GA 0.133%+Sulphur 60%+Pyraclostrobin 5%;
jj. GA 0.133%+Sulphur 60%+Azoxystrobin 5%;
kk. GA 0.133%+Sulphur 60%+Trifloxystrobin 5%;
ll. GA 0.133%+Sulphur 60%+Picoxystrobin 5%;
mm. GA 0.2%+Sulphur 60%+Hexaconazole 4%;
nn. GA 0.2%+Sulphur 60%+Difenoconazole 5%;
oo. GA 0.2%+Sulphur 60%+Epoxiconazole 7.5%;
pp. GA 0.2%+Sulphur 60%+Prothioconazole 7.5%;
qq. GA 0.2%+Sulphur 60%+Propiconazole 7.5%;
rr. GA 0.2%+Sulphur 60%+Fluxapyroxad 5%.

[CLAIM 7]. The synergistic granular agrochmemical composition as claimed in claim 1, wherein the composition for graunule formulation comprises:
a. gibberellic acid present in an amount of 0.001 to 10%w/w;
b. one or more of compound selected chlorantraniliprole, cyantraniliprole, tetraniliprole, zinc, sulphur, triacontanol, cyclaniliprole, flubendiamide, fipronil, clothianidin, thiamethoxam, imidacloprid, bifenthrin, flonicamid, tolfenpyrad, diafenthiuron, profenofos, abamectin, dimethomorph, pyraclostrobin, metiram, mancozeb, chlorothalonil, propineb, cyazofamid, hexaconazole, difenoconazole, epoxiconazole, prothioconazole, propiconazole, fluxapyroxad, azoxystrobin, trifloxystrobin, picoxystrobin present in an amount of 0.01 to 90%w/w;
c. dispersing agent present in an amount of 3-30%w/w
d. wetting agent present in an amount of 0.05-6 %w/w;
e. antifoaming agen present in an amount of 0.05-1.00 %w/w;
f. carrier present in an amount of 1-88%w/w;

[CLAIM 8]. The synergistic granular agrochmemical composition as claimed in claim 1, wherein dispersing agent is selected from alkylnaphthalene sulfonate sodium salt, sodium polycarboxylate, naphthalene sulfonic acid, sodium salt condensates with formaldehyde, polyalcoxylated alkylphenol, naphthalene sulfonic acid formaldehyde condensate, phenol sulfonic acid urea formaldehyde condensate, methyl naphthalene-formaldehyde-condensate sodium salt, naphthalene condensates, polyacrylates and phosphate esters, calcium lignosulfonate, sodium lignosulfonate, sodium lignosulfonate-sulfomethylated.

[CLAIM 9]. The synergistic granular agrochmemical composition as claimed in claim 1, wherein wetting agent is selected from sodium N-methyl-N-oleoyl taurate, alkyl naphthalene sulfonate-sodium salt, mixture of isomers of dibutyl naphthalene sulphonic acid sodium salt, sodium di-isopropyl naphthalene sulphonate, sodium Lauryl sulfate, dioctyl sulfate, phosphate esters, sulphosuccinates and non-ionic such as tridecyl alcohol ethoxylate, alkyl or alkaryl sulfonates such as alkylbenzene sulfonates, alpha olefin sulfonate, ethoxylated or non-ethoxylated alkyl or alkaryl carboxylates, alkyl or alkaryl phosphate esters, alkyl polysaccharide, di or mono alkyl sulfosuccinate derivatives, alpha olefin sulfonates, di-alkyl sulphosuccinates, butyl, dibutyl, isopropyl and di-isopropyl naphthalene sulfonate salts, C12 alkyl benzene sulfonate or C10-C16 alkyl benzene sulfonate, organosilicons surfactants includes trisiloxane ethoxylate, polyoxyethylene methyl polysiloxane, polyoxyalkylene methyl polysiloxane, polyether polymethyl siloxane copolymer, trisiloxane heptamethyl, Polyalkyleneoxide modified heptamethyl trisiloxane, polyether modified polysiloxane, may or may not be in modified form, may be liquid or powder form or mixture thereof.

[CLAIM 10]. The synergistic granular agrochmemical composition as claimed in claim 1, wherein antifoaming agent is polydimethyl siloxane.

[CLAIM 11]. The synergistic granular agrochmemical composition as claimed in claim 1, wherein carrier is china clay, silica, lactose anhydrous, lactose monohydrate, ammonium sulphate, sodium sulphate anhydrous, corn starch, urea, EDTA, urea formaldehyde resin, diatomaceous earth, kaolin, bentonite, kieselguhr, fuller's earth, attapulgite clay, bole, loess, talc, chalk, dolomite, limestone, lime, calcium carbonate, powdered magnesia, magnesium oxide, magnesium sulphate, sodium chloride, gypsum, calcium sulphate, pyrophyllite, silicates and silica gels; fertilizers such as, for example, ammonium sulphate, ammonium phosphate, ammonium nitrate and urea; natural products of vegetable origin such as, for example, grain meals and flours, bark meals, wood meals, nutshell meals and cellulosic powders; and synthetic polymeric materials such as, for example, ground or powdered plastics and resins, bentonites, zeolites, titanium dioxide, iron oxides and hydroxides, aluminium oxides and hydroxides, or organic materials such as bagasse, charcoal, or synthetic organic polymers.

[CLAIM 12]. The synergistic granular agrochmemical composition as claimed in claim 1, wherein the preferred combinations of active ingredients for sand coated granule formulation in said composition comprises:
a. GA0.08%+Fipronil0.6%+Clothianidin0.75%;
b. GA0.08%+Fipronil0.6%+Thiamethoxam1%;
c. GA0.08%+Fipronil0.6%+Imidacloprid0.75%;
d. GA0.08%+Fipronil0.6%+Bifenthrin0.75%;
e. GA0.1%+Zinc2%+Triacontanol0.1%+Chlorantraniliprole 0.4%;
f. GA0.1%+Zinc2%+Triacontanol0.1%+Cyantraniliprole0.6%;
g. GA0.1%+Zinc2%+Triacontanol0.1%+Tetraniliprole0.6%;
h. GA0.1%+Zinc2%+Triacontanol0.1%+Flubendiamide0.7%.

[CLAIM 13]. The synergistic granular agrochmemical composition as claimed in claim 1, wherein the composition for sand coated granule (GR) and Controlled Release Granule (CR-GR) formulation comprises:
a. gibberellic acid present in an amount of 0.001 to 10%w/w;
b. one or more of compound selected Zinc, Sulphur, Triacontanol, Chlorantraniliprole, Cyantraniliprole, Tetraniliprole, Cyclaniliprole, Flubendiamide, Fipronil, Clothianidin, Thiamethoxam, Imidacloprid, Bifenthrin, present in an amount of 0.01 to 90%w/w;
c. wetting agent present in an amount of 0.05-6 %w/w;
d. dispersing agent present in an amount of 3-30%w/w;
e. solvent present in an amount of 1-10%w/w;
f. carrier present in an amount of 1-88%w/w;
g. colouring agent present in an amount of 0.05-1.00%w/w;
h. controlled release agent present in an amount of 0.5-4.0%w/w.

[CLAIM 14]. The synergistic granular agrochmemical composition as claimed in claim 1, wherein dispersing agent is selected from copolymer of propylene oxide (PO) and ethylene oxide (EO) and/or an ethoxylated tristyrene phenol, copolymer of PO and EO is alpha-butyl-omega-hydroxypoly (oxypropylene) block polymer with poly(oxyethylene), ethoxylated tristyrene phenol is alpha-[2,4,6-tris[1-(phenyl)ethyl] phenyl]-omega-hydroxy poly(oxyethylene, poly(oxy-1,2-ethanediyl)-alpha-C10-15alkyl-omega-hydroxy phosphate or sulphate and/or a C10-13alkylbenzenesulfonic acid, tristyrylphenols, nonylphenols, Di nonylphenol and octyl phenols, styryl phenol polyethoxyester phosphate, alkoxylated C14-20fatty amines.

[CLAIM 15]. The synergistic granular agrochmemical composition as claimed in claim 1, wherein wetting agent is selected from mono C2-6 alkyl ether of a poly C2-4alkylene oxide block copolymer, condensation product of castor oil and polyC2-4alkylene oxide, alkoxylated castor oil, carboxylates, sulphates, sulphonates, alcohol ethoxylates, alkyl phenol ethoxylates, fatty acid ethoxylates, sorbitan esters, ethoxylated fats or oils, amine ethoxylates, phosphate esters, ethylene oxide - propylene oxide copolymers, fluorocarbons, polyethylene glycol resin, polyalkylene glycol ether, polyalkoxylated nonyl phenyl, alkoxylated primary alcohol, ethoxylated distyrylphenol, ethoxylated distyrylphenol sulphate, ethoxylated tristyrylphenol phosphate, tristyrylphenol phosphate ester, hydroxylated stearic acid polyalkylene glycol polymer, and their corresponding salts, ethoxylated distyrylphenol, ethoxylated distyrylphenol sulphate, ethoxylated tristyrylphenol phosphate, tristyrylphenol phosphate ester, tristyrylphenol phosphate potassium salt, sodium dodecyl sulfate (SDS).

[CLAIM 16]. The synergistic granular agrochmemical composition as claimed in claim 1, wherein solvent is selected from fatty acid methyl ester, cyclohexane, xylene, mineral oil or kerosene, mixtures or substituted naphthalene, mixtures of mono- and polyalkylated aromatics, dibutyl phthalate or dioctyl phthalate, ethylene glycol monomethyl or mono ethyl ether, butyrolactone, octanol, castor oil, soybean oil, cottonseed oil, epoxidised coconut oil or soybean oil, aromatic hydrocarbons, dipropyleneglycol monomethyl ether, polypropylene glycol [M.W. 2000-4000], polyoxyethylene polyoxypropylene glycols, polyoxypropylene polyoxyethylene glycols, diethyleneglycol, polyethylene glycol [M.W. 200-4000 amu], methoxy polyethylene glycols 350, 550, 750, 2000, 5000; glycerol, methyl oleate, n-octanol, alkyl phosphates such as tri-n-butyl phosphate, propylene carbonate and isoparaffinic, tetrahydrofurfuryl alcohol, gamma-butyrolactone, N-methyl-2-pyrrolidone, tetramethylurea, dimethylsulfoxide, N,N-dimethylacetamide , Diacetone alcohol, Polybutene, Propylene carbonate, Di propylene glycol isomer mixture.

[CLAIM 17]. The synergistic granular agrochmemical composition as claimed in claim 1, wherein carrier is selected from diatomaceous earth, attapulgite or zeolites, dolomite, limestone, silica, fly ash, hydrated lime, wheat flour, wood flour, ground wheat straw, cellulose and soy flour, bentonite, kaolin, attapulgite, diatomaceous earth, calcium carbonate, talc, muscovite mica, fused sodium potassium, sand granules (silicon dioxide), aluminum silicate , perlite, talc and muscovite mica, urea, sulfur-coated urea, isobutylidene diurea, ammonium nitrate, ammonium sulfate, ammonium phosphate, triple super phosphate, phosphoric acid, potassium sulfate, potassium nitrate, potassium metaphosphate, potassium chloride, dipotassium carbonate, potassium oxide and a combination of these, calcium, magnesium, sulfur, iron, manganese, copper, zinc; oxides, humic acid, wood floor, calcium silicate, cellulose granules, magnesium stearate.

[CLAIM 18]. The synergistic granular agrochmemical composition as claimed in claim 1, wherein colouring agent is selected from crystal violet, thalocyano dye chlorinated, aerosol green ffb dye, rodamine, azo compound.

[CLAIM 19]. The synergistic granular agrochmemical composition as claimed in claim 1, wherein controlled release agent is selected from xanthan gum, PVK, carboxymethyl celluloses, polyvinyl alcohols, gelatin, sodium carboxymethylcellulose, hydroxyethylcellulose, Sodium Polyacrylate, modified starch, Paraffin wax, Polyvinyl acetate,Montan wax and vinyl acetate, Polyethylene Glycol 6000, Cationic hydro soluble polymer, C4 alkylated Polyvinyl pyrrolidone