DESC:
FIELD OF THE DISCLOSURE:
The present disclosure relates to an agrochemical composition, and in particular, a herbicidal composition comprising a PS II photosynthesis inhibitor herbicide and an acetolactate synthase inhibitor herbicide. More particularly, the present disclosure relates to a herbicidal composition comprising an anilide herbicide and a pyrimidinylsulfonylurea herbicide. The present disclosure also relates to a process for preparation of the herbicidal composition and a method for controlling weeds using the same thereof.

BACKGROUND OF THE DISCLOSURE:
Herbicides are chemical substances, which are used to specifically control the weeds. The mode of action for herbicides is a biochemical or physical mechanism, which it uses to control unwanted plants or weeds. Most herbicides control unwanted plants or weeds by disrupting or altering one or more of the metabolic processes of plants. However, there are certain species of unwanted plants/weeds or groups of unwanted plants/weeds, which are not susceptible to certain herbicides. This may be because either the herbicides use different biochemical pathways, or the herbicides have slightly different enzymes. Therefore, herbicides are often chosen for use based on their mode of action.

Furthermore, compositions containing herbicides have been used for decades for weed control, however, they have some disadvantages. They have none/insufficient herbicidal activity against specific harmful/unwanted plants, the spectrum of harmful/unwanted plants which can be controlled with the herbicides is not broad enough, the selectivity of herbicides in and the compatibility with crops is too low, thereby causing unwanted damage and/or unwanted reduced harvest yields of the crops, the initial herbicidal activity is not acceptable or not strong enough and/or the herbicidal activity does not last long enough. For these reasons, there is a constant need to develop herbicidal combinations which overcome the aforementioned disadvantages.

The use of herbicidal combinations is a widespread and documented practice in the agricultural community. Herbicidal combinations offer significant advantages over individual applications including improved and extended weed control, reduced herbicide application rates and reduced costs, shorter contact times for improved results, less stringent use restrictions, improved selectivity, improved spectrum of weed control, and reduced residue problems. However, choice of inactive ingredients is critical in such combinations as many times, addition of an active ingredient to a composition of another single active ingredient further aggravates the stability problems.

Propanil is an anilide herbicide having chemical name 3',4'-dichloropropionanilide, and is a widely used contact herbicide. However, propanil is prone to hydrolysis in addition to having a relatively low melting point. The formation of a paste containing water may lead to further difficulties in stability during processing if the energy input during the paste formation is too high. Thus, there are several constraints on the inactive ingredients that could be used for preparing the granules of propanil.

Propyrisulfuron is a pyrimidinylsulfonylurea herbicide having chemical name 1-(2-chloro-6-propylimidazo[1,2-b]pyridazin-3-ylsulfonyl)-3-(4,6-dimethoxypyrimidin-2-yl)urea. Propyrisulfuron is used as a rice herbicide to control annual and perennial paddy weeds, including Echinochloa spp., sedges and broadleaf weeds. Propyrisulfuron shows safer profiles for human health and the environment.

Patent application CN106489972A discloses a herbicidal composition containing promazine sulfometuron methyl and propanil as active ingredients in a weight ratio of 1:1 to 1:100. The composition may also comprise an agrochemically active compound (propyrisulfuron). Further, the application fails to disclose the aspect dealing with improved stability and suspensibility of compositions comprising propanil and propyrisulfuron.

PCT publication WO2016116797A1 discloses a composition comprising modified crystalline propanil and at least another pesticide (propyrisulfuron). However, the publication fails to disclose the aspect dealing with improved stability and suspensibility of the composition.

The inventors of the present disclosure have found that the known compositions comprising propanil in combination with propyrisulfuron suffer from poor suspensibility and often fail the wet sieve test as well as these compositions have low shelf life. These products display a considerable amount of sedimentation with time, often forming hard rock-type lumps at the bottom of the storage containers. The increased sedimentation further aggravates the problem of nozzle clogging during the spraying application by farmers. As a result, it has been observed that when such a composition is prepared as a diluted liquid or a solution to be sprayed, the same does not remain sprayable after the passage of a certain amount of time because of the high insoluble content. This can sometimes lead to a farmer rejecting an otherwise useful product, which is certainly undesirable.

There thus remains a need for development of stable herbicidal compositions comprising propanil and propyrisulfuron, preferably in its free acid form, which address the aforementioned challenges and also do not affect the efficacy associated with the herbicidal compositions.

OBJECTIVES OF THE DISCLOSURE:
It is a primary objective of the present disclosure to provide a stable agrochemical composition, preferably a herbicidal composition.

It is another objective of the present disclosure to provide an agrochemical composition comprising a PS II photosynthesis inhibitor herbicide and an acetolactate synthase inhibitor herbicide.

It is another objective of the present disclosure to provide an agrochemical composition comprising an anilide herbicide and a pyrimidinylsulfonylurea herbicide.

It is another objective of the present disclosure to provide an agrochemical composition comprising an anilide herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent and at least one dispersing agent.

It is another objective of the present disclosure to provide a process for preparation of an agrochemical composition comprising an anilide herbicide and a pyrimidinylsulfonylurea herbicide.

It is another objective of the present disclosure to provide a method for controlling weeds using the agrochemical composition comprising an anilide herbicide and a pyrimidinylsulfonylurea herbicide.

SUMMARY OF THE DISCLOSURE:
In one aspect, the present disclosure provides an agrochemical composition comprising an anilide herbicide and a pyrimidinylsulfonylurea herbicide.

In another aspect, the present disclosure provides a process for preparation of the agrochemical composition comprising an anilide herbicide and a pyrimidinylsulfonylurea herbicide.

In another aspect, the present disclosure provides a method for controlling weeds, said method comprising applying to the plants or a locus thereof, an agrochemical composition comprising an anilide herbicide and a pyrimidinylsulfonylurea herbicide.

DETAILED DESCRIPTION OF THE DISCLOSURE:
The present disclosure now will be described hereinafter with reference to the accompanying examples, in which embodiments of the disclosure are shown. This description is not intended to be a detailed catalogue of all the different ways in which the disclosure may be implemented, or all the features that may be added to the instant disclosure. For example, features illustrated with respect to one embodiment may be incorporated into other embodiments, and features illustrated with respect to a particular embodiment may be deleted from that embodiment. Thus, the disclosure contemplates that in some embodiments of the disclosure, any feature or combination of features set forth herein can be excluded or omitted. In addition, numerous variations and additions to the various embodiments suggested herein will be apparent to those skilled in the art in light of the instant disclosure, which do not depart from the instant disclosure. Hence, the following descriptions are intended to illustrate some particular embodiments of the disclosure, and not to exhaustively specify all permutations, combinations and variations thereof.

Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this disclosure belongs. Although methods and materials similar or equivalent to those described herein can be used in the practice or testing of the disclosure, suitable methods and materials are described herein.

“About” or “approximately” as used herein is inclusive of the stated value and means within an acceptable range of deviation for the particular value as determined by one of ordinary skill in the art, considering the measurement in question and the error associated with measurement of the particular quantity (i.e., the limitations of the measurement system). For example, “about” can mean within one or more standard deviations, or within ± 10% or ± 5% of the stated value.

Recitation of ranges of values are merely intended to serve as a shorthand method of referring individually to each separate value falling within the range, unless otherwise indicated herein, and each separate value is incorporated into the specification as if it were individually recited herein. The endpoints of all ranges are included within the range and independently combinable. As used herein, all numerical values or numerical ranges include integers within such ranges and fractions of the values or the integers within ranges unless the context clearly indicates otherwise. Thus, for example, reference to a range of 90-100%, includes 91%, 92%, 93%, 94%, 95%, 95%, 97%, etc., as well as 91.1%, 91.2%, 91.3%, 91.4%, 91.5%, etc., 92.1%, 92.2%, 92.3%, 92.4%, 92.5%, etc., and so forth. All methods described herein can be performed in a suitable order unless otherwise indicated herein or otherwise clearly contradicted by context.

The use of the terms “a”, “an” and “the” and similar referents (especially in the context of the following claims) are to be construed to cover both the singular and the plural, unless otherwise indicated herein or clearly contradicted by context. The terms first, second etc., as used herein are not meant to denote any particular ordering, but simply for convenience to denote a plurality of, for example, layers.

The terms “comprising”, “having”, “including”, and “containing” are to be construed as open-ended terms (i.e., meaning “including, but not limited to”) unless otherwise noted.

The use of any and all examples, or exemplary language (e.g., “such as”), is intended merely to better illustrate the disclosure and does not pose a limitation on the scope of the disclosure unless otherwise claimed. No language in the specification should be construed as indicating any non-claimed element as essential to the practice of the disclosure as used herein.

While the disclosure has been described with reference to an exemplary embodiment, it will be understood by those skilled in the art that various changes may be made, and equivalents may be substituted for elements thereof without departing from the scope of the disclosure. In addition, many modifications may be made to adapt a particular situation or material to the teachings of the disclosure without departing from the essential scope thereof. Therefore, it is intended that the disclosure is not limited to the particular embodiment disclosed as the best mode contemplated for carrying out this disclosure, but that the disclosure will include all embodiments falling within the scope of the appended claims.

The term “control” relates to a weed, includes control of the weed, as well as protecting a plant, a portion of the plant, or a plant seed from attack or invasion by said weed.

The expression of various quantities in terms of “%” or “% w/w” means the percentage by weight of the total composition unless otherwise specified.

As used herein, the term “agrochemical” refers to all active substances which can be used in the agrochemical field, i.e., fungicides, bactericides, insecticides, acaricides, nematicides, molluscicides, rodenticides, repellents, plant growth regulators, herbicides and safeners, and plant nutrients. Subsequently, the term “herbicides” encompasses both herbicides as well as plant growth regulators, as far as this does not otherwise emerge from the context.

The term “herbicide” as used herein denotes a compound which controls or modifies the growth of undesired weeds/plants.

The term “herbicidally effective amount” indicates the quantity of such a compound or combination of such compounds which is capable of controlling or modifying effect on the growth of harmful plants/undesired vegetation/weeds. Controlling effects include all deviation from natural development, for example, killing, retardation, leaf burn, albinism, dwarfism, etc.

The term “plants” refer to all physical parts of a plant, including seeds, seedlings, saplings, roots, tubers, stems, stalks, foliage and fruits. The term “locus” refers to an area of planted crops or a location where the weeds occur or grows or can occur or grow and is intended to include soil, medium of growth other than soil.

As used herein, the term “pre-emergence” refers to the time point before seedlings emerge from the ground. When any herbicide is applied at pre-emergence stage, it prevents establishment of the germinated weed seedlings.

As used herein, the term “post-emergence” refers to the time point after seedlings emerge from the ground. When any herbicide is applied at post-emergence stage, it prevents growth of the germinated weed seedlings.

As used herein “kraft-lignosulfonate” refers to low molecular weight dispersing agent, with a low degree of sulfonation. It is as a primary dispersant in dry and water-based agricultural chemicals and in disperses dyestuff formulations. Kraft lignosulfonate is sodium lignosulfonate with a degree of sulfonation of 0.5.

While developing a water-dispersible granule (WG or WDG) comprising an anilide herbicide and a pyrimidinylsulfonylurea herbicide, it was surprisingly found by the inventors of the present disclosure that the integrity of WDG can be maintained using a combination of a wetting agent and a dispersing agent. The combination of a wetting agent and a dispersing agent in a particular ratio facilitates the WDG formation. The selected combination of the wetting agent and dispersing agent in a selective weight ratio is found to successfully retain the integrity of the actives in the formulation which results in greater suspensibility and dispersibility as well as improved wet sieve retention.

Accordingly in an embodiment, the present disclosure provides a stable agrochemical composition.

Accordingly in an embodiment, the present disclosure provides a stable herbicidal composition.

It is another objective of the present disclosure to provide an agrochemical composition comprising a PS II photosynthesis inhibitor herbicide and an acetolactate synthase inhibitor herbicide.

It is another objective of the present disclosure to provide an agrochemical composition comprising at least one PS II photosynthesis inhibitor herbicide and at least one acetolactate synthase inhibitor herbicide.

In another embodiment, the PS II photosynthesis inhibitor herbicide comprises triazines, triazinones, uracils, phenyl carbamates, ureas, amides, or combinations thereof.

In a preferred embodiment, the PS II photosynthesis inhibitor herbicide comprises amide herbicides.

In a preferred embodiment, the amide herbicide comprises acetamide herbicides, anilide herbicides, or combinations thereof.

In another embodiment, the acetolactate synthase inhibitor herbicide comprises imidazolinone, triazolopyrimidine-type 1, triazolopyrimidine-type 2, triazolinones, sulfonanilides, pyrimidinyl benzoates, sulfonylurea, or combinations thereof.

In a preferred embodiment, the acetolactate synthase inhibitor herbicide comprises sulfonylurea herbicides.

In a preferred embodiment, the sulfonylurea herbicide comprises pyrimidinylsulfonylurea herbicides, sulfonylaminocarbonyltriazolinone herbicides, triazinylsulfonylurea herbicides, or combinations thereof.

In another embodiment, the present disclosure provides an agrochemical composition comprising an anilide herbicide and a pyrimidinylsulfonylurea herbicide.

In another embodiment, the present disclosure provides an agrochemical composition comprising at least one anilide herbicide and at least one pyrimidinylsulfonylurea herbicide.

As used throughout the disclosure, the anilide herbicide, the pyrimidinylsulfonylurea herbicide, or other active ingredients include their salts, esters, ethers, polymorphs including solvates and hydrates. A salt includes salts that retain the biological effectiveness and properties of the active ingredient, and which are not biologically or otherwise undesirable, and include derivatives of the disclosed compounds in which the parent compound is modified by making inorganic and organic, non-toxic, acid or base addition salts thereof. The salts can be synthesized from the parent compound by conventional chemical methods.

In an embodiment, anilide herbicide is selected from the group comprising propanil, chloranocryl, cisanilide, cypromid, erlujixiancaoan, etobenzanid, monalide, pentanochlor, or combinations thereof.

In a preferred embodiment, the anilide herbicide is propanil.

In an embodiment, the pyrimidinylsulfonylurea herbicide is selected from the group comprising propyrisulfuron, amidosulfuron, azimsulfuron, bensulfuron, chlorimuron, cyclosulfamuron, ethoxysulfuron, flazasulfuron, flucetosulfuron, flupyrsulfuron, foramsulfuron, halosulfuron, imazosulfuron, mesosulfuron, metazosulfuron, methiopyrisulfuron, monosulfuron, monosulfuron-ester, nicosulfuron, orthosulfamuron, oxasulfuron, primisulfuron, pyrazosulfuron, rimsulfuron, sulfometuron, sulfosulfuron, trifloxysulfuron, zuomihuanglong, or combinations thereof.

In a preferred embodiment, the pyrimidinylsulfonylurea herbicide is propyrisulfuron.

In an embodiment, the present disclosure provides an agrochemical composition comprising an anilide herbicide and a pyrimidinylsulfonylurea herbicide, wherein the anilide herbicide is propanil.

In an embodiment, the present disclosure provides an agrochemical composition comprising an anilide herbicide and a pyrimidinylsulfonylurea herbicide, wherein the pyrimidinylsulfonylurea herbicide is propyrisulfuron.

In another embodiment, the present disclosure provides an agrochemical composition comprising propanil and propyrisulfuron.

According to an embodiment of the present disclosure, the agrochemical composition comprises from about 10% w/w to about 90% w/w of the anilide herbicide, based on total weight of the agrochemical composition.

According to an embodiment of the present disclosure, the agrochemical composition comprises from about 20% w/w to about 80% w/w of the anilide herbicide, based on total weight of the agrochemical composition.

According to an embodiment of the present disclosure, the agrochemical composition comprises from about 30% w/w to about 70% w/w of the anilide herbicide, based on total weight of the agrochemical composition.

According to an embodiment of the present disclosure, the agrochemical composition comprises from about 50% w/w to about 70% w/w of the anilide herbicide, based on total weight of the agrochemical composition.

In a preferred embodiment, the agrochemical composition comprises from about 60% w/w to about 62.5% w/w of the anilide herbicide, based on total weight of the agrochemical composition.

In an embodiment, the present disclosure provides an agrochemical composition comprising an anilide herbicide and a pyrimidinylsulfonylurea herbicide, wherein the composition comprises from about 50% w/w to about 70% w/w of the anilide herbicide, based on total weight of the agrochemical composition.

In an embodiment, the present disclosure provides an agrochemical composition comprising an anilide herbicide and a pyrimidinylsulfonylurea herbicide, wherein the composition comprises from about 50% w/w to about 70% w/w of propanil, based on total weight of the agrochemical composition.

In a preferred embodiment, the agrochemical composition comprises from about 60% w/w to about 62.5% w/w of propanil, based on total weight of the agrochemical composition.

In a preferred embodiment, the agrochemical composition comprises about 60% w/w propanil, based on total weight of the agrochemical composition.

According to an embodiment of the present disclosure, the agrochemical composition comprises from about 0.1% w/w to about 50% w/w of the pyrimidinylsulfonylurea herbicide, based on total weight of the agrochemical composition.

According to an embodiment of the present disclosure, the agrochemical composition comprises from about 0.1% w/w to about 30% w/w of the pyrimidinylsulfonylurea herbicide, based on total weight of the agrochemical composition.

According to an embodiment of the present disclosure, the agrochemical composition comprises from about 1% w/w to about 15% w/w of the pyrimidinylsulfonylurea herbicide, based on total weight of the agrochemical composition.

In a preferred embodiment, the agrochemical composition comprises from about 2% w/w to about 2.15% w/w of the pyrimidinylsulfonylurea herbicide, based on total weight of the agrochemical composition.

In an embodiment, the present disclosure provides an agrochemical composition comprising an anilide herbicide and a pyrimidinylsulfonylurea herbicide, wherein the composition comprises from about 1% w/w to about 15% w/w of the pyrimidinylsulfonylurea herbicide, based on total weight of the agrochemical composition.

In an embodiment, the present disclosure provides an agrochemical composition comprising an anilide herbicide and a pyrimidinylsulfonylurea herbicide, wherein the composition comprises from about 1% w/w to about 15% w/w of propyrisulfuron, based on total weight of the agrochemical composition.

In a preferred embodiment, the agrochemical composition comprises from about 2% w/w to about 2.15% w/w of propyrisulfuron, based on total weight of the agrochemical composition.

In a preferred embodiment, the agrochemical composition comprises about 2% w/w propyrisulfuron, based on total weight of the agrochemical composition.

In an embodiment, the present disclosure provides an agrochemical composition comprises from about 50% w/w to about 70% w/w of the anilide herbicide and from about 1% w/w to about 15% w/w of the pyrimidinylsulfonylurea herbicide, based on total weight of the agrochemical composition.

In an embodiment, the present disclosure provides an agrochemical composition comprises from about 50% w/w to about 70% w/w of propanil and from about 1% w/w to about 15% w/w of propyrisulfuron, based on total weight of the agrochemical composition.

In another preferred embodiment, the composition comprises from about 50% w/w to about 70% w/w anilide herbicide and from about 1% w/w to about 15% w/w pyrimidinylsulfonylurea herbicide of total weight of the composition.

According to a preferred embodiment, the present disclosure provides an agrochemical composition comprising an anilide herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent and at least one dispersing agent.

In another embodiment, the present disclosure provides a herbicidal composition comprising:
(a) an anilide herbicide;
(b) a pyrimidinylsulfonylurea herbicide;
(c) at least one wetting agent;
(d) at least one dispersing agent; and
(e) at least one agrochemically acceptable excipient.

According to a preferred embodiment, the present disclosure provides an agrochemical composition comprising an anilide herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent and at least one dispersing agent, wherein the anilide herbicide is propanil.

According to a preferred embodiment, the present disclosure provides an agrochemical composition comprising an anilide herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent and at least one dispersing agent, wherein the pyrimidinylsulfonylurea herbicide is propyrisulfuron.

According to a preferred embodiment, the present disclosure provides an agrochemical composition comprising propanil, propyrisulfuron, at least one wetting agent and at least one dispersing agent.

According to an embodiment of the present disclosure, the at least one wetting agent comprises an alkyl sulfate salt.

According to a preferred embodiment, the alkyl sulfate salt comprises sodium alkyl sulfate salts comprising sodium lauryl sulfate, potassium lauryl sulfate, ammonium lauryl sulfate, or combinations thereof, preferably sodium lauryl sulfate.

In another embodiment, the wetting agent comprises an alkyl sulfate salt selected from sodium lauryl sulfate, potassium lauryl sulfate, ammonium lauryl sulfate, or combinations thereof.

According to an embodiment of the present disclosure, the at least one dispersing agent is selected from the group comprising polycarboxylate dispersant, lignosulfonates, kraft-lignosulfonate, sodium lignosulfonate, calcium lignosulfonate, potassium lignosulfonate, salts of lignosulfonate, or combinations thereof.

According to a preferred embodiment, the polycarboxylate dispersant comprises sodium polycarboxylate, potassium polycarboxylate, ultra-high speed polymeric dispersant, ammonium salt of a polyelectrolyte, dispersant polymer, acrylic co-polymer, acid resin copolymer, styrene acrylic polymer, and sodium salt of maleic anhydride copolymer, or combinations thereof, preferably potassium polycarboxylate.

In another embodiment, the dispersing agent is selected from the group comprising
potassium polycarboxylate, sodium polycarboxylate, lignosulfonates, kraft-lignosulfonate, sodium lignosulfonate, calcium lignosulfonate, potassium lignosulfonate, salts of lignosulfonate, acrylic co-polymer, acid resin copolymer, styrene acrylic polymer, and sodium salt of maleic anhydride copolymer, or combinations thereof.

According to an embodiment, the present disclosure provides an agrochemical composition comprising:
a) an anilide herbicide;
b) a pyrimidinylsulfonylurea herbicide;
c) at least one wetting agent; and
d) at least one dispersing agent.

According to an embodiment, the present disclosure provides an agrochemical composition comprising:
a) propanil;
b) propyrisulfuron;
c) at least one wetting agent; and
d) at least one dispersing agent.

According to an embodiment, the present disclosure provides an agrochemical composition comprising:
a) propanil;
b) propyrisulfuron;
c) an alkyl sulfate salt; and
d) a polycarboxylate dispersant.

According to a preferred embodiment, the present disclosure provides an agrochemical composition comprising:
a) propanil;
b) propyrisulfuron;
c) sodium lauryl sulfate; and
d) a polycarboxylate dispersant.

According to a preferred embodiment, the present disclosure provides an agrochemical composition comprising:
a) propanil;
b) propyrisulfuron;
c) an alkyl sulfate salt; and
d) potassium polycarboxylate.

According to a preferred embodiment, the present disclosure provides an agrochemical composition comprising:
a) propanil;
b) propyrisulfuron;
c) sodium lauryl sulfate; and
d) potassium polycarboxylate.

According to a preferred embodiment, the present disclosure provides an agrochemical composition comprising:
a) propanil present in an amount of about 60% w/w to about 62.5% w/w;
b) propyrisulfuron present in an amount of about 2% w/w to about 2.15% w/w;
c) sodium lauryl sulfate; and
d) potassium polycarboxylate of total weight of the composition.

In an embodiment of the present disclosure, the agrochemical composition comprises from about 0.1% w/w to about 30% w/w of the alkyl sulfate salt, based on total weight of the agrochemical composition.

In an embodiment of the present disclosure, the agrochemical composition comprises from about 0.1% w/w to about 20% w/w of the alkyl sulfate salt, based on total weight of the agrochemical composition.

In an embodiment of the present disclosure, the agrochemical composition comprises from about 0.1% w/w to about 10% w/w of the alkyl sulfate salt, based on total weight of the agrochemical composition.

In an embodiment of the present disclosure, the agrochemical composition comprises from about 1% w/w to about 10% w/w of the alkyl sulfate salt, based on total weight of the agrochemical composition.

In an embodiment of the present disclosure, the agrochemical composition comprises from about 2.5% w/w to about 3.5% w/w of the alkyl sulfate salt, based on total weight of the agrochemical composition.

In an embodiment of the present disclosure, the agrochemical composition comprises from about 2.5% w/w to about 3.5% w/w of sodium lauryl sulfate, based on total weight of the agrochemical composition.

In an embodiment, the present disclosure provides an agrochemical composition comprises from about 50% w/w to about 70% w/w of anilide herbicide, from about 1% w/w to about 15% w/w of pyrimidinylsulfonylurea herbicide and from about 2.5% w/w to about 3.5% w/w of the alkyl sulfate salt, based on total weight of the agrochemical composition.

In an embodiment, the present disclosure provides an agrochemical composition comprises from about 50% w/w to about 70% w/w of propanil, from about 1% w/w to about 15% w/w of propyrisulfuron and from about 2.5% w/w to about 3.5% w/w of the sodium lauryl sulfate, based on total weight of the agrochemical composition.

In an embodiment of the present disclosure, the agrochemical composition comprises from about 0.1% w/w to about 30% w/w of the polycarboxylate dispersant, based on total weight of the agrochemical composition.

In an embodiment of the present disclosure, the agrochemical composition comprises from about 0.1% w/w to about 20% w/w of the polycarboxylate dispersant, based on total weight of the agrochemical composition.

In an embodiment of the present disclosure, the agrochemical composition comprises from about 0.1% w/w to about 10% w/w of the polycarboxylate dispersant, based on total weight of the agrochemical composition.

In an embodiment of the present disclosure, the agrochemical composition comprises from about 1% w/w to about 10% w/w of the polycarboxylate dispersant, based on total weight of the agrochemical composition.

In an embodiment of the present disclosure, the agrochemical composition comprises from about 6.8% w/w to about 7.5% w/w of the polycarboxylate dispersant, based on total weight of the agrochemical composition.

In an embodiment of the present disclosure, the agrochemical composition comprises from about 6.8% w/w to about 7.5% w/w of potassium polycarboxylate, based on total weight of the agrochemical composition.

In another preferred embodiment, the composition comprises from about 1% w/w to about 10% w/w wetting agent and from about 1% w/w to about 10% w/w dispersing agent of total weight of the composition.

In an embodiment, the present disclosure provides an agrochemical composition comprises from about 50% w/w to about 70% w/w of anilide herbicide, from about 1% w/w to about 15% w/w of pyrimidinylsulfonylurea herbicide and from about 6.8% w/w to about 7.5% w/w of the polycarboxylate dispersant, based on total weight of the agrochemical composition.

In an embodiment, the present disclosure provides an agrochemical composition comprises from about 50% w/w to about 70% w/w of propanil, from about 1% w/w to about 15% w/w of propyrisulfuron and from about 6.8% w/w to about 7.5% w/w of the potassium polycarboxylate, based on total weight of the agrochemical composition.

In an embodiment, the present disclosure provides an agrochemical composition comprises from about 50% w/w to about 70% w/w of propanil, from about 1% w/w to about 15% w/w of propyrisulfuron, from about 2.5% w/w to about 3.5% w/w of the sodium lauryl sulfate and from about 6.8% w/w to about 7.5% w/w of the potassium polycarboxylate, based on total weight of the agrochemical composition.

According to a preferred embodiment, the present disclosure provides an agrochemical composition comprising:
a) propanil present in an amount from about 60% w/w to about 62.5% w/w;
b) propyrisulfuron present in an amount from about 2% w/w to about 2.15% w/w;
c) sodium lauryl sulfate present in an amount from about 2.5% w/w to about 5.5% w/w; and
d) potassium polycarboxylate present in an amount from about 6.8% w/w to about 7.5% w/w of total weight of the composition.

According to an embodiment of the present disclosure, the agrochemical composition comprises an anilide herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent and at least one dispersing agent, wherein the at least one wetting agent and at least one dispersing agent are present in a weight ratio ranging from about 0.1:1 to about 100:1, preferably from about 0.1:1 to about 90:1, preferably from about 0.1:1 to about 80:1, preferably from about 0.1:1 to about 70:1, preferably from about 0.1:1 to about 60:1, preferably from about 0.1:1 to about 50:1, preferably from about 0.1:1 to about 40:1, preferably from about 0.1:1 to about 30:1, and preferably from about 0.1:1 to about 20:1.

According to an embodiment of the present disclosure, the agrochemical composition comprises an anilide herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent and at least one dispersing agent, wherein the at least one wetting agent and at least one dispersing agent are present in a weight ratio ranging from about 0.1:1 to about 10:1.

According to an embodiment of the present disclosure, the agrochemical composition comprises propanil, propyrisulfuron, at least one wetting agent and at least one dispersing agent, wherein the at least one wetting agent and at least one dispersing agent are present in a weight ratio ranging from about 0.1:1 to about 10:1.

According to an embodiment of the present disclosure, the agrochemical composition comprises an anilide herbicide, a pyrimidinylsulfonylurea herbicide, an alkyl sulfate salt and a polycarboxylate dispersant, wherein the alkyl sulfate salt and the polycarboxylate dispersant are present in a weight ratio ranging from about 0.1:1 to about 10:1.

According to an embodiment of the present disclosure, the agrochemical composition comprises an anilide herbicide, a pyrimidinylsulfonylurea herbicide, an alkyl sulfate salt and a polycarboxylate dispersant, wherein the alkyl sulfate salt and the polycarboxylate salt are present in a weight ratio ranging from about 0.1:1 to about 10:1.

According to an embodiment of the present disclosure, the agrochemical composition comprises an anilide herbicide, a pyrimidinylsulfonylurea herbicide, sodium lauryl sulfate and potassium polycarboxylate, wherein the sodium lauryl sulfate and potassium polycarboxylate are present in a weight ratio ranging from about 0.1:1 to about 10:1.

According to an embodiment of the present disclosure, the agrochemical composition comprises propanil, propyrisulfuron, sodium lauryl sulfate and potassium polycarboxylate, wherein the sodium lauryl sulfate and potassium polycarboxylate are present in a weight ratio ranging from about 0.1:1 to about 10:1.

According to an embodiment of the present disclosure, the agrochemical composition comprises propanil, propyrisulfuron, sodium lauryl sulfate and potassium polycarboxylate, wherein the sodium lauryl sulfate and potassium polycarboxylate are present in a weight ratio of about 0.36:1.

According to an embodiment of the present disclosure, the agrochemical composition comprises propanil, propyrisulfuron, sodium lauryl sulfate and potassium polycarboxylate, wherein the sodium lauryl sulfate and potassium polycarboxylate are present in a weight ratio of about 0.46:1.

Unless otherwise indicated, the ratios disclosed throughout the specification are weight ratios.

According to an embodiment of the present disclosure, the agrochemical composition comprises an anilide herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent and at least one dispersing agent, wherein the anilide herbicide and the pyrimidinylsulfonylurea herbicide are present in a weight ratio of about 10:1 to about 100:1.

According to an embodiment of the present disclosure, the agrochemical composition comprises an anilide herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent and at least one dispersing agent, wherein the anilide herbicide and the pyrimidinylsulfonylurea herbicide are present in a weight ratio of about 20:1 to about 80:1.

According to an embodiment of the present disclosure, the agrochemical composition comprises an anilide herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent and at least one dispersing agent, wherein the anilide herbicide and the pyrimidinylsulfonylurea herbicide are present in a weight ratio of about 20:1 to about 50:1.

According to an embodiment of the present disclosure, the agrochemical composition comprises propanil, propyrisulfuron, an alkyl sulfate salt and a polycarboxylate dispersant, wherein propanil and propyrisulfuron are present in a weight ratio of about 20:1 to about 50:1.

According to an embodiment of the present disclosure, the agrochemical composition comprises propanil, propyrisulfuron, sodium lauryl sulfate and potassium polycarboxylate, wherein propanil and propyrisulfuron are present in a weight ratio of about 20:1 to about 50:1.

According to an embodiment of the present disclosure, the agrochemical composition comprises propanil, propyrisulfuron, sodium lauryl sulfate and potassium polycarboxylate, wherein propanil and propyrisulfuron are present in a weight ratio of about 30:1.

According to an embodiment of the present disclosure, the agrochemical composition comprises propanil, propyrisulfuron, sodium lauryl sulfate and potassium polycarboxylate, wherein propanil and propyrisulfuron are present in a weight ratio of about 29.06:1.

In another embodiment, the inventors of the present disclosure found that the combination of propanil and propyrisulfuron when mixed with an alkyl sulfate salt and a polycarboxylate dispersant showed superior suspensibility and wet sieve retention.

In yet another embodiment, the inventors of the present disclosure noted the ease of making compositions using propanil, propyrisulfuron, an alkyl sulfate salt and a polycarboxylate dispersant when produced according to present disclosure.

According to an embodiment, the agrochemical composition obtained according to present disclosure is capable of dispersing quickly in water. According to an embodiment, the agrochemical composition obtained according to present disclosure leads to optimum suspensibility while dispersed in water.

According to an embodiment, the present disclosure provides an agrochemical composition comprising propanil and propyrisulfuron having superior suspensibility and wet sieve retention. The composition provides several advantages such as ease of handling, ease of use, reduced work exposure, reduced toxicity, reduced spillage and waste disposal, less field drift, free-flow and significant reduction in dust hazards.

In yet another embodiment, the present disclosure provides an agrochemical composition comprising:
a) propanil;
b) propyrisulfuron;
c) sodium lauryl sulfate; and
d) potassium polycarboxylate,
wherein the composition exhibits greater than about 75% w/w suspension when measured according to the Collaborative International Pesticides Analytical Council (CIPAC) guideline Miscellaneous Techniques (MT) 184 and/or MT 184.1.

In yet another embodiment, the present disclosure provides an agrochemical composition comprising:
a) propanil;
b) propyrisulfuron;
c) sodium lauryl sulfate; and
d) potassium polycarboxylate,
wherein the composition exhibits less than about 0.1% w/w wet sieve retention when measured according to CIPAC guideline MT 185.

In yet another embodiment, the present disclosure provides an agrochemical composition comprising:
a) propanil present in an amount from about 60% w/w to about 62.5% w/w;
b) propyrisulfuron present in an amount from about 2% w/w to about 2.15% w/w;
c) sodium lauryl sulfate present in an amount from about 2.5% w/w to about 3.5% w/w; and
d) potassium polycarboxylate present in an amount from about 6.8% w/w to about 7.5% w/w of total weight of the composition,
wherein the composition exhibits greater than about 75% w/w suspension when measured according to CIPAC guideline MT 184 and/or MT 184.1; and
wherein the composition exhibits less than about 0.1% w/w wet sieve retention when measured according to CIPAC guideline MT 185.

In yet another embodiment, the composition exhibits greater than 80% w/w, preferably greater than about 85% w/w suspension when measured according to CIPAC guideline MT 184 and/or MT 184.1.

According to a preferred embodiment, the present disclosure provides an agrochemical composition comprising an anilide herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent, at least one dispersing agent, and at least one agrochemically acceptable excipient.

According to a preferred embodiment, the present disclosure provides an agrochemical composition comprising propanil, propyrisulfuron, at least one wetting agent, at least one dispersing agent, and at least one agrochemically acceptable excipient.

According to a preferred embodiment, the present disclosure provides an agrochemical composition comprising propanil, propyrisulfuron, an alkyl sulfate salt, a polycarboxylate dispersant, and at least one agrochemically acceptable excipient.

According to a preferred embodiment, the present disclosure provides an agrochemical composition comprising propanil, propyrisulfuron, sodium lauryl sulfate, potassium polycarboxylate, and at least one agrochemically acceptable excipient.

In yet another embodiment, the present disclosure provides an agrochemical composition comprising:
a) propanil;
b) propyrisulfuron;
c) sodium lauryl sulfate;
d) potassium polycarboxylate; and
e) at least one agrochemically acceptable excipient.

According to an embodiment of the present disclosure, the agrochemically acceptable excipients are selected from one or more of emulsifiers, colorants, thickeners/binders, antifreeze agents, antifoaming agents, antioxidants, solvents, preservatives, glidants, anticaking agents, pH-regulating agents, buffering agents, formulation aids, disintegrants, inert, wetting agents, or combinations thereof.

In another embodiment, emulsifiers which can be advantageously employed herein can be readily determined by those skilled in the art and include various non-ionic, anionic, cationic, and amphoteric emulsifiers, or a blend of two or more emulsifiers. Examples of non-ionic emulsifiers useful in preparing the emulsifiable concentrates include the polyalkylene glycol ethers and condensation products of alkyl and aryl phenols, aliphatic alcohols, aliphatic amines or fatty acids with ethylene oxide, propylene oxides such as the ethoxylated alkyl phenols and carboxylic esters solubilized with the polyol or polyoxyalkylene. Cationic emulsifiers include quaternary ammonium compounds and fatty amine salts. Anionic emulsifiers include the oil-soluble salts (e.g., calcium) of alkylaryl sulfonic acids, oil-soluble salts or sulfated polyglycol ethers and appropriate salts of phosphated polyglycol ether.

In an embodiment, colorants may be selected from iron oxide, titanium oxide and Prussian Blue, and organic dyestuffs, such as alizarin dyestuffs, azo dyestuffs or metal phthalocyanine dyestuffs, and trace elements, such as salts of iron, manganese, boron, copper, cobalt, molybdenum and zinc.

In an embodiment, thickener or gelling agent may be selected from but not limited to molasses, granulated sugar, alginates, karaya gum, jaguar gum, tragacanth gum, polysaccharide gum, mucilage, xanthan gum or combination thereof. In another embodiment, the binder may be selected from silicates such as magnesium aluminium silicate, polyvinyl acetates, polyvinyl acetate copolymers, polyvinyl alcohols, polyvinyl alcohol copolymers, celluloses, including ethylcelluloses and methylcelluloses, hydroxymethyl celluloses, hydroxypropylcelluloses, hydroxymethylpropyl-celluloses, polyvinylpyrolidones, dextrins, malto-dextrins, polysaccharides, fats, oils, proteins, gum arabics, shellacs, vinylidene chloride, vinylidene chloride copolymers, acrylic copolymers, starches, polyvinylacrylates, zeins, gelatin, carboxymethylcellulose, chitosan, polyethylene oxide, acrylimide polymers and copolymers, polyhydroxyethyl acrylate, methylacrylimide monomers, alginate, ethylcellulose, polychloroprene and syrups or mixtures thereof; polymers and copolymers of vinyl acetate, methyl cellulose, vinylidene chloride, acrylic, cellulose, polyvinylpyrrolidone and polysaccharide; polymers and copolymers of vinylidene chloride and vinyl acetate-ethylene copolymers; combinations of polyvinyl alcohol and sucrose; plasticizers such as glycerol, propylene glycol, polyglycols.

In another embodiment, antifreeze agent(s) added to the composition may be alcohols selected from the group comprising of but not limited to ethylene glycol, 1,2-propylene glycol, 1,3-propylene glycol, 1,2-butanediol, 1,3-butanediol, 1,4-butanediol, 1,4-pentanediol, 3-methyl-1,5-pentanediol, 2,3-dimethyl-2,3-butanediol, trimethylol propane, mannitol, sorbitol, glycerol, pentaerythritol, 1,4-cyclohexanedimethanol, xylenol, bisphenols such as bisphenol A or the like. In addition, ether alcohols such as diethylene glycol, triethylene glycol, tetraethylene glycol, polyoxyethylene or polyoxypropylene glycols of molecular weight up to about 4000, diethylene glycol monomethylether, diethylene glycol monoethylether, triethylene glycol monomethylether, butoxyethanol, butylene glycol monobutylether, dipentaerythritol, tripentaerythritol, tetrapentaerythritol, diglycerol, triglycerol, tetraglycerol, pentaglycerol, hexaglycerol, heptaglycerol, octaglycerol.

According to an embodiment, antifoam agent may be selected from polydimethoxysiloxane, polydimethylsiloxane, alkyl poly acrylates, castor oil, fatty acids, fatty acids esters, fatty acids sulfate, fatty alcohol, fatty alcohol esters, fatty alcohol sulfate, foot olive oil, mono & di glyceride, paraffin oil, paraffin wax, poly propylene glycol, silicones oil, vegetable fats, vegetable fats sulfate, vegetable oil, vegetable oil sulfate, vegetable wax, vegetable wax sulfate, agents based on silicon or magnesium stearate, and blend of maltodextrin, and methylated silica.

The agrochemical composition may also comprise one or more antioxidants. Preferably, the agrochemical formulation comprises an antioxidant. Antioxidants are, for example, amino acids (e.g., glycine, histidine, tyrosine, tryptophan) and derivatives thereof, imidazole and imidazole derivatives (e.g., urocanic acid), peptides, such as, for example, D,L-carnosine, D-carnosine, L-carnosine and derivatives thereof (e.g., anserine), carotenoids, carotenes (e.g., a-carotene, ß-carotene, lycopene) and derivatives thereof, lipoic acid and derivatives thereof (e.g., dihydrolipoic acid), aurothioglucose, propylthiouracil and further thio compounds (e.g., thioglycerol, thiosorbitol, thioglycolic acid, thioredoxin, glutathione, cysteine, cystine, cystamine and the glycosyl, N-acetyl, methyl, ethyl, propyl, amyl, butyl, lauryl, palmitoyl, oleyl, ?-linoleyl, cholesteryl and glyceryl esters thereof), and salts thereof, dilauryl thiodipropionate, distearyl thiodipropionate, thiodipropionic acid and derivatives thereof (esters, ethers, peptides, lipids, nucleotides, nucleosides and salts), and sulfoximine compounds (e.g., buthionine sulfoximines, homocysteine sulfoximine, buthionine sulfones, penta-, hexa-, heptathionine sulfoximine) in very low tolerated doses (e.g., pmol/kg to pmol/kg), also metal chelating agents (e.g., a-hydroxy fatty acids, EDTA, EGTA, phytic acid, lactoferrin), a-hydroxy acids (e.g., citric acid, lactic acid, malic acid), humic acids, bile acid, bile extracts, gallic esters (e.g., propyl, octyl and dodecyl gallate), flavonoids, catechins, bilirubin, biliverdin and derivatives thereof, unsaturated fatty acids and derivatives thereof (e.g., ?-linolenic acid, linoleic acid, arachidonic acid, oleic acid), folic acid and derivatives thereof, hydroquinone and derivatives thereof (e.g., arbutin), ubiquinone and ubiquinol, and derivatives thereof, vitamin C and derivatives thereof (e.g., ascorbyl palmitate, stearate, dipalmitate, acetate, Mg ascorbyl phosphates, sodium and magnesium ascorbate, disodium ascorbyl phosphate and sulfate, potassium ascorbyl tocopheryl phosphate, chitosan ascorbate), isoascorbic acid and derivatives thereof, tocopherols and derivatives thereof (e.g., tocopheryl acetate, linoleate, oleate and succinate, tocophereth-5, tocophereth-10, tocophereth-12, tocophereth-18, tocophereth-50, tocophersolan), vitamin A and derivatives (e.g., vitamin A palmitate), the coniferyl benzoate of benzoin resin, rutin, rutinic acid and derivatives thereof, disodium rutinyl disulfate, cinnamic acid and derivatives thereof (e.g., ferulic acid, ethyl ferulate, caffeeic acid), kojic acid, chitosan glycolate and salicylate, butylhydroxytoluene, butylhydroxyanisol, nordihydroguaiacic acid, nordihydroguaiaretic acid, trihydroxybutyrophenone, uric acid and derivatives thereof, mannose and derivatives thereof, selenium and selenium derivatives (e.g., selenomethionine), stilbenes and stilbene derivatives (e.g., stilbene oxide, trans-stilbene oxide). According to the disclosure, suitable derivatives (salts, esters, sugars, nucleotides, nucleosides, peptides, and lipids) and mixtures of these specified active ingredients or plant extracts (e.g., teatree oil, rosemary extract and rosemarinic acid) which comprise these antioxidants can be used. In general, mixtures of the aforementioned antioxidants are possible.

According to an embodiment, examples of suitable solvents are water, oils of vegetable, or derivatives. In principle, solvent mixtures may also be used.

In another embodiment, suitable preservatives are for example benzothiazoles, 1,2-benzisothiazolin-3-one, sodium dichloro-s-triazinetrione, sodium benzoate, potassium sorbate, 1,2-phenyl-isothiazolin-3-one, inter chloroxylenol paraoxybenzoate butyl, benzoic acid, and combinations thereof.

In another embodiment, suitable inert are for example precipitated silica, amorphous silica, titanium dioxide, kaolin, bentonite, soapstone, talc, attapulgite, ceramic, montmorillonite, pumice, sepiolite, diatomaceous earth, sand, clay, dolomite, calcite, magnesium oxides, magnesium carbonates, sucrose, corn starch, citric acid and its salts, and combinations thereof.

In an embodiment, the wetting agent may be selected from dialkyl naphthalene sulphonate formaldehyde condensate, dialkyl naphthalene sulphonate sodium salt and sodium naphthalene sulfonate - formaldehyde condensate.

In another embodiment, the composition comprises from about 0.1% w/w to about 30% w/w agrochemically acceptable excipient of total weight of the composition.

According to an embodiment, the present disclosure provides an agrochemical composition comprising anilide herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent, at least one dispersing agent, and at least one agrochemically acceptable excipient, wherein the agrochemical composition is present in a form of a solid formulation.

In an embodiment, the agrochemical composition is selected from Powder for dry soil application (DS), Granule/soil applied (GR), Controlled (Slow or Fast) release granules (CR), Jambo balls or bags (bags in water soluble pouch), Water soluble granule (SG), Water dispersible granule (WG or WDG), or Soil Applied Granules (SAG).

According to an embodiment, the agrochemical composition is present in a form of a water dispersible granule (WG or WDG).

In another embodiment, the composition is in a form of water-dispersible granules.

In yet another embodiment, the present disclosure provides a water-dispersible granular composition comprising:
a) an anilide herbicide;
b) a pyrimidinylsulfonylurea herbicide;
c) at least one wetting agent;
d) at least one dispersing agent; and
e) at least one agrochemically acceptable excipient.

In yet another embodiment, the present disclosure provides a water-dispersible granular composition comprising:
a) propanil;
b) propyrisulfuron;
c) an alkyl sulfate salt;
d) a polycarboxylate dispersant; and
e) at least one agrochemically acceptable excipient.

In yet another embodiment, the present disclosure provides a water-dispersible granular composition comprising:
a) propanil;
b) propyrisulfuron;
c) an alkyl sulfate salt;
d) a polycarboxylate salt; and
e) at least one agrochemically acceptable excipient.

In yet another embodiment, the present disclosure provides a water-dispersible granular composition comprising:
a) propanil;
b) propyrisulfuron;
c) sodium lauryl sulfate;
d) potassium polycarboxylate; and
e) at least one agrochemically acceptable excipient.

In an embodiment, the present invention provides a WDG composition comprising propanil, propyrisulfuron, sodium lauryl sulfate, potassium polycarboxylate, and at least one agrochemically acceptable excipient, either in the form of a tank mix or a pre-formulated (pre-mix) composition.

In an embodiment, the present invention provides a WDG composition comprising propanil, propyrisulfuron, sodium lauryl sulfate, potassium polycarboxylate, and at least one agrochemically acceptable excipient, in the form of a pre-formulated (pre-mix) composition.

In yet another embodiment, the present disclosure provides a pre-mix WDG composition comprising:
a) propanil;
b) propyrisulfuron;
c) sodium lauryl sulfate;
d) potassium polycarboxylate; and
e) at least one agrochemically acceptable excipient.

In another aspect, the present disclosure provides a process for the preparation of the agrochemical composition, wherein the agrochemical composition comprises an anilide herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent, at least one dispersing agent and at least one agrochemically acceptable excipient.

In yet another aspect, the present disclosure provides a process for the preparation of the herbicidal composition, the process comprising:
(a) mixing an anilide herbicide with a pyrimidinylsulfonylurea herbicide, at least one wetting agent, at least one dispersing agent and at least one agrochemically acceptable excipient to obtain a mixture;
(b) milling the mixture obtained in step (a);
(c) preparing a dough using the mixture;
(d) extruding the dough to obtain granules; and
(e) drying the granules to obtain the herbicidal composition.

In yet another aspect, the present disclosure provides a process for the preparation of the agrochemical composition, the process comprising:
(a) mixing an anilide herbicide with a pyrimidinylsulfonylurea herbicide, an alkyl sulfate salt, a polycarboxylate dispersant and at least one agrochemically acceptable excipient to obtain a mixture;
(b) milling the mixture obtained in step (a);
(c) preparing a dough using the mixture;
(d) extruding the dough to obtain granules; and
(e) drying the granules to obtain the agrochemical composition.

In yet another aspect, the present disclosure provides a process for the preparation of the agrochemical composition, the process comprising:
(a) mixing propanil with propyrisulfuron, sodium lauryl sulfate, potassium polycarboxylate and at least one agrochemically acceptable excipient to obtain a mixture;
(b) milling the mixture obtained in step (a);
(c) preparing a dough using the mixture;
(d) extruding the dough to obtain granules; and
(e) drying the granules to obtain the agrochemical composition.

A person skilled in the art can easily understand that the essence of the process of preparing the composition as described in the embodiments of this disclosure is not in performing the activities in the given order. For example, milling the mixture of step (a) and preparing dough can be simultaneously performed and making the dough does not need to be done only after milling the mixture of step (a) as is provided in the embodiments. Also, in step (a), mixing of propanil with propyrisulfuron, an alkyl sulfate salt and a polycarboxylate dispersant, can be carried out by mixing all the components together at the same time or an alkyl sulfate salt and/or a polycarboxylate dispersant can be mixed with either propanil or propyrisulfuron separately first and then brought together for mixing.

In an embodiment, in step (b) of the process, shear mixer, kneader, plough shear mixer may be used.

In another embodiment, drying the granules is done in a fluidized bed dryer.

In another embodiment, the moisture content of the dried granules obtained in step (e) is less than about 2% w/w.

In an embodiment, the granules are dried at a temperature range of 45-50°C to achieve a moisture content of less than about 2% w/w.

It will also be appreciated by any person skilled in the art that similar suspensibility and wet sieve parameters can be achieved by preparing granules by spray drying rather than extrusion as long as the granules prepared from the process comprise propanil, propyrisulfuron, an alkyl sulfate salt, and a polycarboxylate dispersant.

In another embodiment, the present disclosure provides use of the agrochemical composition for controlling weeds, wherein the agrochemical composition comprises comprising anilide herbicide and a pyrimidinylsulfonylurea herbicide.

In another embodiment, the present disclosure provides use of a herbicidal composition for controlling weeds, wherein the composition comprises an anilide herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent, at least one dispersing agent, and at least one agrochemically acceptable excipient.

In another embodiment, the present disclosure provides use of the agrochemical composition for controlling weeds, wherein the agrochemical composition comprises comprising anilide herbicide, a pyrimidinylsulfonylurea herbicide, an alkyl sulfate salt, a polycarboxylate dispersant, and at least one agrochemically acceptable excipient.

In another embodiment, the present disclosure provides use of the agrochemical composition for controlling weeds, wherein the agrochemical composition comprises comprising propanil, propyrisulfuron, sodium lauryl sulfate, potassium polycarboxylate, and at least one agrochemically acceptable excipient.

In another aspect, the present disclosure provides a method for controlling weeds, said method comprising applying to the plants or locus thereof an agrochemical composition comprising an anilide herbicide and a pyrimidinylsulfonylurea herbicide.

In another aspect, the present disclosure provides a method for controlling weeds, by applying an effective amount of a herbicidal composition to a plant or a locus thereof, the composition comprising: an anilide herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent, at least one dispersing agent, and at least one agrochemically acceptable excipient.

In another aspect, the present disclosure provides a method for controlling weeds, said method comprising applying to the plants or locus thereof an agrochemical composition comprising an anilide herbicide, a pyrimidinylsulfonylurea herbicide, an alkyl sulfate salt, a polycarboxylate dispersant, and at least one agrochemically acceptable excipient.

In another aspect, the present disclosure provides a method for controlling weeds, said method comprising applying to the plants or locus thereof an agrochemical composition comprising propanil, propyrisulfuron, sodium lauryl sulfate, potassium polycarboxylate, and at least one agrochemically acceptable excipient.

In another embodiment, the composition of the present disclosure is used to control weeds in various agricultural crops. Non-limiting examples of weeds controlled by the composition of the present disclosure include: Brassicaceae weeds: Raphanus raphanistrum, Raphanus sativus, Sinapis arvensis, Capsella bursa-pastoris, Brassica juncea, Brassica campestris, Descurainia pinnata, Rorippa islandica, Rorippa sylvestris, Thlaspi arvense, Myagrum rugosum, Lepidium virginicum, Coronopus didymus, and combinations thereof. Non-limiting examples of weeds controlled by the composition of the present disclosure include: Poaceae weeds: Dinebra retroflexa, Cynodon dactylon, Echinochloa colonum, Echinochloa crusgalli, Setaria viridis, Setaria faberi, Setaria glauca, Setaria ilosa ate, Digitaria ciliaris, Digitaria sanguinalis, Digitaria horizontalis, Digitaria insularis, Eleusine indica, Poa annua, Alospecurus aequalis, Alopecurus myosuroides, Avena fatua, Sorghum halepense, Sorghum vulgare, Agropyron repens, Lolium multiflorum, Lolium perenne, Lolium rigidum, Bromus secalinus, Bromus tectorum, Hordeum jubatum, Aegilops cylindrica, Phalaris arundinacea, Phalaris minor, Apera spicaventi, Panicum dichotomiflorum, Panicum texanum, Panicum maximum, Brachiaria reptains Brachiaria platyphylla, Brachiaria ruziziensis, Brachiaria plantaginea, Brachiaria decumbens, Brachiaria brizantha, Brachiaria humidicola, Brachiaria mutica, Cenchrus echinatus, Cenchrus pauciflorus, Eriochloa villosa, Pennisetum setosum, Chloris gayana, Chloris barbata, Eragrostis ilosa, Rhynchelitrum repens, Dactyloctenium aegyptium, Ischaemum rugosum, Oryza sativa, Paspalum notatum, Paspalum maritimum, Pennisetum clandestinum, Pennisetum setosum, Rottboellia cochinchinensis, and combinations thereof.

In another embodiment, the composition of the present disclosure is used to control weeds in various agricultural crops.

In another embodiment, the various (target) agricultural crops include, but not limited to, corn, rice, wheat, barley, rye, oat, sorghum, cotton, soybean, peanut, buckwheat, beet, rapeseed, sunflower, sugar cane, tobacco, etc.; vegetables: solanaceous vegetables such as eggplant, tomato, pimento, pepper, potato, etc., cucurbit vegetables such as cucumber, pumpkin, zucchini, water melon, melon, squash, etc., cruciferous vegetables such as radish, white turnip, horseradish, kohlrabi, Chinese cabbage, cabbage, leaf mustard, broccoli, cauliflower, etc., asteraceous vegetables such as burdock, crown daisy, artichoke, lettuce, etc, liliaceous vegetables such as green onion, onion, garlic, and asparagus, ammiaceous vegetables such as carrot, parsley, celery, parsnip, etc., chenopodiaceous vegetables such as spinach, Swiss chard, etc., lamiaceous vegetables such as Perilla frutescens, mint, basil, etc, strawberry, sweet potato, Dioscorea japonica, colocasia, etc., flowers, foliage plants, turf grasses, fruits: pome fruits such apple, pear, quince, etc, stone fleshy fruits such as peach, plum, nectarine, Prunus mume, cherry fruit, apricot, prune, etc., citrus fruits such as orange, lemon, rime, grapefruit, etc., nuts such as chestnuts, walnuts, hazelnuts, almond, pistachio, cashew nuts, macadamia nuts, etc. berries such as blueberry, cranberry, blackberry, raspberry, etc., grape, kaki fruit, olive, plum, banana, coffee, date palm, coconuts, etc. , trees other than fruit trees; tea, mulberry, flowering plant, trees such as ash, birch, dogwood, Eucalyptus, Ginkgo biloba, lilac, maple, Quercus, poplar, Judas tree, Liquidambar formosana, plane tree, zelkova, Japanese arborvitae, fir wood, hemlock, juniper, Pinus, Picea, and Taxus cuspidate, etc.

In an embodiment, the present method for controlling weeds comprises applying a pre-mix composition of propanil and propyrisulfuron.

In an embodiment the pre-mix formulation is in the form of water-dispersible granule (WG or WDG).

According to an embodiment of the present disclosure, the various components of the agrochemical composition can be used individually or already partially or completely mixed with one at least one other to prepare the composition according to the disclosure. It is also possible for them to be packaged and used further as composition such as a kit of parts.

According to an embodiment of the present disclosure, there is provided a kit comprising an anilide herbicide, a pyrimidinylsulfonylurea herbicide, at least one wetting agent, at least one dispersing agent, and at least one agrochemically acceptable excipient.

According to an embodiment of the present disclosure, there is provided a kit comprising an anilide herbicide, a pyrimidinylsulfonylurea herbicide, an alkyl sulfate salt, a polycarboxylate dispersant, and at least one agrochemically acceptable excipient.

According to an embodiment, the kit of parts comprises:
(a) an anilide herbicide;
(b) a pyrimidinylsulfonylurea herbicide;
(c) an alkyl sulfate salt;
(d) a polycarboxylate dispersant; and
(e) at least one agrochemically acceptable excipient;
and optionally further comprises:
instructions for use.

According to an embodiment of the present disclosure, there is provided a kit comprising propanil, propyrisulfuron, sodium lauryl sulfate, potassium polycarboxylate, and at least one agrochemically acceptable excipient.

According to an embodiment, the kit of parts comprises:
(a) propanil;
(b) propyrisulfuron;
(c) sodium lauryl sulfate;
(d) potassium polycarboxylate; and
(e) at least one agrochemically acceptable excipient;
and optionally further comprises:
instructions for use.

In one embodiment of the disclosure, the kits may include one or more, including all, components that may be used to prepare the agrochemical concentrate composition, e.g., kits may include active ingredients and/or wetting agent and dispersing agent. One or more of the components may already be combined or pre-formulated. In those embodiments where more than two components are provided in a kit, the components may already be combined and as such are packaged in a single container such as a vial, bottle, can, pouch, bag, or canister.

In view of the above, it will be seen that the several advantages of the disclosure are achieved, and other advantageous results attained. Although the present disclosure has been disclosed in full, it will be understood that numerous additional modifications and variations could be made thereto without departing from the scope of the disclosure. The embodiments may be combined together for better understanding of the disclosure, without departing from the scope of the disclosure.

In another embodiment, alternative or multiple embodiments of the disclosure disclosed herein are not to be construed as limitations. Each embodiment can be referred to and claimed individually or in any combination with other embodiments of the disclosure. One or more embodiments of the disclosure can be included in, or deleted from, the disclosure for reasons of convenience and/or patentability.

The disclosure will now be described in more details with reference to the following examples. While the foregoing written description of the disclosure enables one of ordinary skill to make and use what is considered presently to be the best mode thereof, those of ordinary skill will understand and appreciate the existence of variations, combinations, and equivalents of the specific embodiment, method, and examples herein. The disclosure should therefore not be limited by the above-described embodiment, method, and following examples, but by all embodiments and methods within the scope and spirit of the disclosure.

EXAMPLES:
Example 1: Propanil and Propyrisulfuron WDG composition
The agrochemical composition of the present invention was formulated as a water-dispersible granule (WG or WDG).
Ingredients Quantity (% w/w)
Propanil 60.0 to 62.5
Propyrisulfuron 2.0 to 2.15
Sodium lauryl sulfate 2.5 to 3.5
Potassium polycarboxylate 6.8 to 7.5
Kraft-lignosulfonate 2.0 to 3.0
Kaolin Q.S.
Total 100

Process:
Propanil was mixed with propyrisulfuron, alkyl sulfate salt (sodium lauryl sulfate), polycarboxylate dispersant (potassium polycarboxylate) and at least one agrochemically acceptable excipient to obtain a mixture. The mixture was milled, and a dough was prepared. The dough was extruded to obtain granules. The obtained granules were dried at a temperature range of about 45°C to about -50°C to obtain the agrochemical composition.

Examples 2-5: Suspensibility and Wet Sieve Retention Study
A suspensibility and wet sieve retention study of the compositions in Examples 2-5 was performed and the results have been tabulated in Table 1.
Table 1: Suspensibility and Wet Sieve Retention study
Sr. No. Ingredients Amount (% w/w)
Example 2 Example
3 Example
4 Example
5
1 Propanil 62 62 62 62
2 Propyrisulfuron 2.1 2.1 2.1 2.1
3 Potassium polycarboxylate 7.36 7.36 0 7.36
4 Kraft- lignosulfonate 2.7 2.7 2.7 0
5 Sodium lauryl sulfate 3.5 0 3.5 3.5
6 Kaolin Q.S. Q.S. Q.S. Q.S.
Total 100 100 100 100
Suspensibility and Wet sieve retention
Suspensibility 87.71 76.7 40.44 76.19
Wet sieve retention (%) 0.08 3.557 0.302 0.067
Remarks Good dispersion, suspension & wet sieve Moderate
suspension, dispersion;
but poor wet sieve Poor
suspension, dispersion
& wet sieve Moderate suspension, dispersion
& wet sieve

From the results of Table 1, it was observed that Examples 2 and 5 had a combination of an alkyl sulfate salt (sodium lauryl sulfate) and a polycarboxylate dispersant (potassium polycarboxylate). Compositions from both these examples exhibited more than 75% w/w suspensibility and less than 0.1% w/w wet sieve retention when checked according CIPAC guideline MT 184 and CIPAC guideline MT 185, respectively. Compositions from Examples 3 and 4 did not have combination of an alkyl sulfate salt (sodium lauryl sulfate) and a polycarboxylate dispersant (potassium polycarboxylate), and they did not have desired properties i.e., both more than 75% w/w suspensibility and less than 0.1% w/w wet sieve retention when checked according CIPAC guideline MT 184 and CIPAC guideline MT 185, respectively.

Therefore, sodium lauryl sulfate is essential for wet sieve and potassium polycarboxylate is essential for suspension and dispersion. Thus, it is clear from the suspensibility and wet sieve retention parameters study that combination of an alkyl sulfate salt and a polycarboxylate dispersant is necessary for the compositions of propanil and propyrisulfuron to exhibit desired suspensibility and wet sieve retention.

Example 6: Stability at AHS conditions
The water dispersible granule composition as disclosed in Example 1 was evaluated for its stability. The stability of the said composition was determined under accelerated heat stability (AHS) conditions for about 14 days at about 54°C and has been disclosed in Table 2.
Table 2: Stability study
Sr. No. Ingredients 0 day 14 days, AHS
(% w/w) (% w/w)
1 Propanil 61.29 61
2 Propyrisulfuron 2.1 2
3 Suspensibility (Propanil) 89.49 89.11
4 Suspensibility (Propyrisulfuron) 99.2 98.38
5 Wet Sieve Retention on 200 BSS 0.05 0.05

There was no significant change either in the physical or chemical property of the composition, i.e., active ingredient content, wet sieve test, and suspensibility, after accelerated storage for a period of 14 days at 54 ± 2°C.

Example 7: Real time data for stability study
The water dispersible granule composition as disclosed in Example 1 was evaluated for its stability. The stability of the said composition was determined for 6, 12, 18, 24 and 30 months and has been disclosed in Table 3.
Table 3: Stability study
Sr. No. Ingredients 0 day 6 months 12 months 18 months 24 months 30 months
(% w/w)
1 Propanil 61.29 61.2 61.1 60.95 60.85 60.55
2 Propyrisulfuron 2.1 2.07 2.03 2.01 1.99 1.97
3 Suspensibility (Propanil) 89.49 84.87 78.5 76.5 75.5 75
4 Suspensibility (Propyrisulfuron) 99.2 100.2 92 91.5 88.5 88.5
5 Wet Sieve Retention on 200 BSS 0.05 0.08 0.09 0.1 0.11 0.12

Therefore, it was observed that propanil and propyrisulfuron WDG were stable, when stored from a period from 6 months to 30 months.
,CLAIMS:
1. A herbicidal composition comprising:
(a) an anilide herbicide;
(b) a pyrimidinylsulfonylurea herbicide;
(c) at least one wetting agent;
(d) at least one dispersing agent; and
(e) at least one agrochemically acceptable excipient.

2. The composition as claimed in claim 1, wherein the anilide herbicide is selected from the group comprising propanil, chloranocryl, cisanilide, cypromid, erlujixiancaoan, etobenzanid, monalide, pentanochlor, or combinations thereof.

3. The composition as claimed in claim 1, wherein the pyrimidinylsulfonylurea herbicide is selected from the group comprising propyrisulfuron, amidosulfuron, azimsulfuron, bensulfuron, chlorimuron, cyclosulfamuron, ethoxysulfuron, flazasulfuron, flucetosulfuron, flupyrsulfuron, foramsulfuron, halosulfuron, imazosulfuron, mesosulfuron, metazosulfuron, methiopyrisulfuron, monosulfuron, monosulfuron-ester, nicosulfuron, orthosulfamuron, oxasulfuron, primisulfuron, pyrazosulfuron, rimsulfuron, sulfometuron, sulfosulfuron, trifloxysulfuron, zuomihuanglong, or combinations thereof.

4. The composition as claimed in claim 1, wherein the wetting agent comprises an alkyl sulfate salt selected from sodium lauryl sulfate, potassium lauryl sulfate, ammonium lauryl sulfate, or combinations thereof.

5. The composition as claimed in claim 1, wherein the dispersing agent is selected from the group comprising potassium polycarboxylate, sodium polycarboxylate, lignosulfonates, kraft-lignosulfonate, sodium lignosulfonate, calcium lignosulfonate, potassium lignosulfonate, salts of lignosulfonate, acrylic co-polymer, acid resin copolymer, styrene acrylic polymer, and sodium salt of maleic anhydride copolymer, or combinations thereof.

6. The composition as claimed in claim 1, wherein the wetting agent and the dispersing agent are present in a weight ratio ranging from about 0.1:1 to about 10:1.

7. The composition as claimed in claim 1, wherein the agrochemically acceptable excipient is selected from the group comprising emulsifiers, colorants, thickeners/binders, antifreeze agents, antifoaming agents, antioxidants, solvents, preservatives, glidants, anticaking agents, pH-regulating agents, buffering agents, formulation aids, disintegrants, inert, wetting agents, or combinations thereof.

8. The composition as claimed in claim 1, wherein the composition comprises from about 50% w/w to about 70% w/w anilide herbicide and from about 1% w/w to about 15% w/w pyrimidinylsulfonylurea herbicide of total weight of the composition.

9. The composition as claimed in claim 1, wherein the composition comprises from about 1% w/w to about 10% w/w wetting agent and from about 1% w/w to about 10% w/w dispersing agent of total weight of the composition.

10. The composition as claimed in claim 1, wherein the composition is in a form of water-dispersible granules.

11. A water-dispersible granular composition comprising:
(a) propanil;
(b) propyrisulfuron;
(c) an alkyl sulfate salt;
(d) a polycarboxylate salt; and
(e) at least one agrochemically acceptable excipient.

12. The composition as claimed in claim 13, wherein the alkyl sulfate salt and the polycarboxylate salt are present in a weight ratio ranging from about 0.1:1 to about 10:1.

13. A process for preparing a herbicidal composition, the process comprising:
(a) mixing an anilide herbicide with a pyrimidinylsulfonylurea herbicide, at least one wetting agent, at least one dispersing agent and at least one agrochemically acceptable excipient to obtain a mixture;
(b) milling the mixture obtained in step (a);
(c) preparing a dough using the mixture;
(d) extruding the dough to obtain granules; and
(e) drying the granules to obtain the herbicidal composition.

14. Use of a herbicidal composition for controlling weeds, the composition comprising:
(a) an anilide herbicide;
(b) a pyrimidinylsulfonylurea herbicide;
(c) at least one wetting agent;
(d) at least one dispersing agent; and
(e) at least one agrochemically acceptable excipient.

15. A method for controlling weeds by applying an effective amount of a herbicidal composition to a plant or a locus thereof, the composition comprising:
(a) an anilide herbicide;
(b) a pyrimidinylsulfonylurea herbicide;
(c) at least one wetting agent;
(d) at least one dispersing agent; and
(e) at least one agrochemically acceptable excipient.