[001] The present disclosure broadly relates to field of cosmetics and personal hygiene, and particularly relates to a liquid pre-mix composition which can be readily diluted for various applications.
BACKGROUND OF INVENTION
[002] There are many applications for a desirable cleansing composition in view of personal hygiene and personal care products. For a cleansing composition to be desirable, the composition should exhibit good lathering properties, be mild on skin, should also provide moisturizing effects and should satisfy the customers on the aesthetic front. There are many cleansing compositions known in the art, whereby different combination of surfactants has been used to provide effective cleansing systems along with appropriate stabilizers and polymers.
[003] Over the years, the appearance and rheological characteristics of the cleansing composition have started to define a separate class of products known as liquid wash, liquid sanitizers, and sanitizers with a jelly appearance. The consumer expectation has also increased with respect to the sensorial parameters of a cleansing composition. Cleansing composition in a concentrated form are also being increasingly appreciated by the customers owing to the flexibility of dilution offered by them. The viscosity of the composition plays a great role while formulating a desirable concentrated cleansing solution so that the sensorial parameters are retained upon dilution also. The ratios of ingredients such as surfactants, polymers, and electrolytes differ significantly as compared to regular ready-to-use cleansing compositions. Therefore, appropriate working ratios and weight percentages need to be established to obtain a concentrated solution with desirable characteristics. [004] WO0185896A1 discloses aqueous electrolyte containing concentrate used for dishwashing and cleaning hard surfaces.
[005] EP0166608A2 discloses a liquid cleansing composition comprising synthetic polymer, solvent, and electrolyte. It is characterized to be diluted to give half the amount of viscosity as compared to the concentrated form.

[006] Still there is a need to provide a desirable liquid pre-mix composition that satisfies the consumer appeal related to aesthetic and sensorial parameters.
SUMMARY OF THE INVENTION
[007] In an aspect of the present disclosure, there is provided a liquid pre-mix composition comprising: (a) at least one water-insoluble component; (b) at least one polymer; (c) at least one electrolyte; (d) at least one surfactant; and (e) water, wherein water has a weight percentage in a range of 25-40% with respect to the composition. [008] In an aspect of the present disclosure, there is provided a process for preparing a liquid pre-mix composition comprising: (a) at least one water-insoluble component; (b) at least one polymer; (c) at least one electrolyte; (d) at least one surfactant selected from a group consisting of anionic surfactant, amphoteric surfactant, non-ionic surfactant, and combinations thereof; (e) water; and (f) excipient selected from a group consisting of humectant, chelating agent, preservative, antioxidant, fragrance, and combinations thereof, wherein water has a weight percentage in a range of 25-40% with respect to the composition, said process comprising: (i) contacting a combination of the at least one surfactant at a temperature in a range of 70-74È W`c R eZ^V aVcZ`U `W 2/-40 minutes with a stirring at a range of 50-100 rpm, to obtain a first mixture, wherein the at least one surfactant comprises a combination of anionic surfactant and amphoteric surfactant; (ii) contacting the at least one water-insoluble component, the chelating agent, and the non-ionic surfactant, at a temperature in a range of 75-74È, e` `SeRZ_ R dVT`_U mixture; (iii) contacting the first mixture and the second mixture B at a temperature in a range of 70-7/È hZeY deZccZ_X Z_ R cR_XV `W 4/-100 rpm for a time period of 10-20 minutes, to obtain a third mixture; (iv) contacting the third mixture and the at least one polymer at a temperature in a range of 65-64È hZeY deZccZ_X Z_ R cR_ge of 50-100 rpm for a time period of 5-15 minutes, to obtain a fourth mixture; (v) contacting the fourth mixture to the preservative, the antioxidant, the humectant, fragrance, at a temperature in a range of 40-34È hZeY deZccZ_X Z_ R cR_XV `W 4/-80 rpm for a time period of 5-15 minutes, to obtain a fifth mixture; (vi) contacting the fifth mixture to

the at least one electrolyte at a temperature in a range of 35-3/È hZeY deZccZ_X Z_ R range of 40-60 rpm for a time period of 15-25 minutes, to obtain the composition. [009] In an aspect of the present disclosure, there is provided a ready-to-use product obtained from dilution of the composition comprising: (a) at least one water-insoluble component; (b) at least one polymer; (c) at least one electrolyte; (d) at least one surfactant selected from a group consisting of anionic surfactant, amphoteric surfactant, non-ionic surfactant, and combinations thereof; (e) water; and (f) excipient selected from a group consisting of humectant, chelating agent, preservative, antioxidant, fragrance, and combinations thereof, wherein water has a weight percentage in a range of 25-40% with respect to the composition, and wherein the composition is diluted with water in a range of 200-300% with respect to the composition.
[0010] These and other features, aspects, and advantages of the present subject matter will be better understood with reference to the following description and appended claims. This summary is provided to introduce a selection of concepts in a simplified form. This summary is not intended to identify key features or essential features of the claimed subject matter, nor is it intended to be used to limit the scope of the claimed subject matter.
BRIEF DESCRIPTION OF ACCOMPANYING DRAWINGS
[0011] The following drawings form a part of the present specification and are
included to further illustrate aspects of the present disclosure. The disclosure may be
better understood by reference to the drawings in combination with the detailed
description of the specific embodiments presented herein.
[0012] Figure 1 illustrates the graphical representation of kinetics of viscosity with
respect to the dilution of the composition of the present disclosure, in accordance
with an embodiment of the present disclosure.
DETAILED DESCRIPTION OF THE INVENTION
[0013] Those skilled in the art will be aware that the present disclosure is subject to variations and modifications other than those specifically described. It is to be

understood that the present disclosure includes all such variations and modifications. The disclosure also includes all such steps, features, compositions, and compounds referred to or indicated in this specification, individually or collectively, and any and all combinations of any or more of such steps or features. Definitions
[0014] For convenience, before further description of the present disclosure, certain terms employed in the specification, and examples are delineated here. These definitions should be read in the light of the remainder of the disclosure and understood as by a person of skill in the art. The terms used herein have the meanings recognized and known to those of skill in the art, however, for convenience and completeness, particular terms and their meanings are set forth below. [0015] The RrtZc]ed "R", "Rn" Rnd "the" Rre uded to refer to one or to more than one (i.e., to at least one) of the grammatical object of the article. [0016] The termd "comprZde" Rnd "comprZdZng" Rre uded Zn the Znc]udZve, open dende, meaning that additional elements may be included. It is not intended to be construed Rd "condZdtd of on]y".
[0017] Throughout this specification, unless the context requires otherwise the word "comprZde", Rnd vRrZRtZond d uch Rd "comprZded" Rnd "comprZdZng", hZ]] be understood to imply the inclusion of a stated element or step or group of element or steps but not the exclusion of any other element or step or group of element or steps. [0018] The term "Znc]udZng" Zd uded to meRn "Znc]udZng but not ]ZmZted to". "Inc]udZng" Rnd "Znc]udZng but not ]ZmZted to" Rre uded ZnterchRngeRb]y. [0019] Ratios, concentrations, amounts, and other numerical data may be presented herein in a range format. It is to be understood that such range format is used merely for convenience and brevity and should be interpreted flexibly to include not only the numerical values explicitly recited as the limits of the range, but also to include all the individual numerical values or sub-ranges encompassed within that range as if each numerical value and sub-range is explicitly recited.
[0020] For the purposes of the present document, "hRter-insoluble component" Zd defined as any material that remains suspended in the formulation during its shelf-life without any sedimentation. Functionally, water insoluble component could be

one or more of, from the group consisting of pearlizing agents, opacifiers, actives and fillers. "Total Active Surfactant Content" refers to the active amount of all types of surfactant present in the composition. For example, if the only surfactant present in the formulation is 10% of 70% SLES then the total active surfactant content will be 7% with respect to the composition.
[0021] As discussed previously, the field of cleansing compositions is undergoing a lot of change, constant improvement has been the pursuit of many research works in this field. One such area of improvement is in maintaining the viscosity drop experienced by a concentrate solution upon dilution. The compositions disclosed in the prior art comprises high amount of water thereby leaving very less space for modifying weight percentages of other ingredients.
[0022] Pure electrolyte-based dilution thickening systems tend to have very sharp dilution thresholds. Beyond these thresholds, the dilutions may not build viscosity. One of the other requirements in case of the concentrate formulation is that the diluted version of the product should be as good as the readily available formulations in terms aesthetics and feel. Unlike the ready-to-use products wherein the water-insoluble component such as ethylene glycol distearate (EGDS) gets sufficient time for 'aging' during its shelf-life and till the time it reaches the consumer. On the contrary, in case of the concentrates, the pearlescent effects and the aesthetics are expected instantly after the dilution. Therefore, the challenge lies in providing a concentrated solution to the consumers which upon dilution gives a diluted product which has aesthetics and sensorial features at par with readymade available diluted cleansing products.
[0023] The present disclosure provides a pre-liquid composition which provides a combination of electrolyte and a specific polymer that provides a wider operative window for the consumer to dilute the concentrate without any risk of forming unduly watery version of the product. The present disclosure provides a liquid pre-mix composition comprising: (a) at least one water-insoluble component; (b) at least one polymer; (c) at least one electrolyte; (d) at least one surfactant; and (e) water, wherein water has a weight percentage in a range of 25-40% with respect to the composition. The weight percentage range of water is significantly lower than that

disclosed in prior art. Also, the weight percentage range of the water-insoluble component and surfactant as per the present disclosure ensures that the composition retains proper aesthetic appeal. Also, the weight percentage of electrolyte as per the disclosure ensures that during dilution up to the prescribed level, the viscosity of the resulting diluted product is in parity with the existing hand-wash preparations that are sold in a readymade form in the market. The weight percentages of the ingredient also ensure that there is no sharp drop in viscosity even if the consumer ends up pouring little bit extra water during dilution. There is a buffer zone provided for dilution that accounts for any excess of water used up to a particular level during dilution. The present disclosure provides both the pre-mix composition and the diluted composition which are stable in nature and free from any sedimentation and phase separation problems. Thus, the pre-mix composition of the present disclosure provides freedom to consumers in terms of diluting the composition to achieve a ready-to-use product for cleansing purpose. This is associated with reduced wastage of the pre-mix composition and also retains the viscosity in case if the dilution is accidentally happening on a higher side. The specific weight ratios of different components in the pre-mix composition ensures that higher water-insoluble components are present in a lower weight percentage range of water and the water-insoluble components remain stable in concentrated form as well as after diluting the pre-mix composition to obtain the ready-to-use product.
[0024] An excipient is an inactive substance that serves as the vehicle or medium for a drug or other active substance. Excipients in case of the present disclosure includes humectant, chelating agent, preservative, antioxidant, pH modifier, fragrance. The various categories mentioned under excipient category are well known substances to a person skilled in the art.
[0025] Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this disclosure belongs. Although any methods and materials similar or equivalent to those described herein can be used in the practice or testing of the disclosure, the preferred methods, and materials are now described. All publications mentioned herein are incorporated herein by reference.

[0026] The present disclosure is not to be limited in scope by the specific embodiments described herein, which are intended for the purposes of exemplification only. Functionally-equivalent products, compositions, and methods are clearly within the scope of the disclosure, as described herein. [0027] In an embodiment of the present disclosure, there is provided a liquid pre-mix composition comprising: (a) at least one water-insoluble component; (b) at least one polymer; (c) at least one electrolyte; (d) at least one surfactant; and (e) water, wherein water has a weight percentage in a range of 25-40% with respect to the composition.
[0028] In an embodiment of the present disclosure, there is provided a liquid pre-mix composition comprising: (a) at least one water-insoluble component; (b) at least one polymer; (c) at least one electrolyte; (d) at least one surfactant; and (e) water, wherein water has a weight percentage in a range of 25-40% with respect to the composition, and wherein the at least one water-insoluble component to the at least one electrolyte has a weight ratio in a range of 1:2-2:1. In another embodiment of the present disclosure, the at least one water-insoluble component to the at least one electrolyte has a weight ratio in a range of 3:10-1:1.
[0029] In an embodiment of the present disclosure, there is provided a liquid pre-mix composition comprising: (a) at least one water-insoluble component; (b) at least one polymer; (c) at least one electrolyte; (d) at least one surfactant; and (e) water, wherein water has a weight percentage in a range of 25-40% with respect to the composition, and wherein the least one water-insoluble component to the at least one polymer has a weight ratio in a range of 1:2-38:1. In another embodiment of the present disclosure, the least one water-insoluble component to the at least one polymer has a weight ratio in a range of 1:2-15:1. In yet another embodiment of the present disclosure, the least one water-insoluble component to the at least one polymer has a weight ratio in a range of 1:2-3:1.
[0030] In an embodiment of the present disclosure, there is provided a liquid pre-mix composition comprising: (a) at least one water-insoluble component; (b) at least one polymer; (c) at least one electrolyte; (d) at least one surfactant; and (e) water, wherein water has a weight percentage in a range of 25-40% with respect to the

composition, and wherein the at least one water-insoluble component to the at least one surfactant has a weight ratio in a range of 12:100-4:100. In another embodiment of the present disclosure, the at least one water-insoluble component to the at least one surfactant has a weight ratio in a range of 8:100-4:100.# [0031] In an embodiment of the present disclosure, there is provided a liquid pre-mix composition comprising: (a) at least one water-insoluble component; (b) at least one polymer; (c) at least one electrolyte; (d) at least one surfactant; and (e) water, wherein water has a weight percentage in a range of 25-40% with respect to the composition, and wherein the composition has a viscosity in a range of 5500-8500 cps.
[0032] In an embodiment of the present disclosure, there is provided a liquid pre-mix composition comprising: (a) at least one water-insoluble component; (b) at least one polymer; (c) at least one electrolyte; (d) at least one surfactant; and (e) water, wherein water has a weight percentage in a range of 25-40% with respect to the composition, and wherein the at least one water-insoluble component has a weight percentage in a range of 2.5-4.5% with respect to the composition.# [0033] In an embodiment of the present disclosure, there is provided a liquid pre-mix composition comprising: (a) at least one water-insoluble component; (b) at least one polymer; (c) at least one electrolyte; (d) at least one surfactant; and (e) water, wherein water has a weight percentage in a range of 25-40% with respect to the composition, and wherein the at least one water-insoluble component has a weight percentage in a range of 2.6-3.9% with respect to the composition. [0034] In an embodiment of the present disclosure, there is provided a liquid pre-mix composition comprising: (a) at least one water-insoluble component; (b) at least one polymer; (c) at least one electrolyte; (d) at least one surfactant; and (e) water, wherein water has a weight percentage in a range of 25-40% with respect to the composition, and wherein the at least one polymer has a weight percentage in a range of 0.12-4.5% with respect to the composition. In another embodiment of the present disclosure, the at least one polymer has a weight percentage in a range of 1-4.0% with respect to the composition. In yet another embodiment of the present disclosure,

the at least one polymer has a weight percentage in a range of 2-3.5% with respect to the composition.#
[0035] In an embodiment of the present disclosure, there is provided a liquid pre-mix composition comprising: (a) at least one water-insoluble component; (b) at least one polymer; (c) at least one electrolyte; (d) at least one surfactant; and (e) water, wherein water has a weight percentage in a range of 25-40% with respect to the composition, and wherein the at least one electrolyte has a weight percentage in a range of 3-5% with respect to the composition. In another embodiment of the present disclosure, the at least one electrolyte has a weight percentage in a range of 3-4% with respect to the composition.#
[0036] In an embodiment of the present disclosure, there is provided a liquid pre-mix composition comprising: (a) at least one water-insoluble component; (b) at least one polymer; (c) at least one electrolyte; (d) at least one surfactant; and (e) water, wherein water has a weight percentage in a range of 25-40% with respect to the composition, and wherein the at least one surfactant has a weight percentage in a range of 35-60% with respect to the composition. In another embodiment of the present disclosure, the at least one surfactant has a weight percentage in a range of 40-55% with respect to the composition.#
[0037] In an embodiment of the present disclosure, there is provided a liquid pre-mix composition comprising: (a) at least one water-insoluble component; (b) at least one polymer; (c) at least one electrolyte; (d) at least one surfactant; and (e) water, wherein water has a weight percentage in a range of 25-40% with respect to the composition, and wherein the at least one water-insoluble component to the at least one electrolyte has a weight ratio in a range of 1:2-2:1, and the least one water-insoluble component to the at least one polymer has a weight ratio in a range of 1:2-38:1, and the at least one water-insoluble component to the at least one surfactant has a weight ratio in a range of 0.12:1-0.04:1. In another embodiment of the present disclosure, the at least one water-insoluble component to the at least one electrolyte has a weight ratio in a range of 3:10-1:1, and the least one water-insoluble component to the at least one polymer has a weight ratio in a range of 1:2-15:1, and the at least

one water-insoluble component to the at least one surfactant has a weight ratio in a range of 0.08:1-0.04:1.#
[0038] In an embodiment of the present disclosure, there is provided a liquid pre-mix composition comprising: (a) at least one water-insoluble component; (b) at least one polymer; (c) at least one electrolyte; (d) at least one surfactant; and (e) water, wherein water has a weight percentage in a range of 25-40% with respect to the composition, and wherein the at least one water-insoluble component has a weight percentage in a range of 2.5-4.5% with respect to the composition, and the at least one polymer has a weight percentage in a range of 0.12-4.5% with respect to the composition, and the at least one electrolyte has a weight percentage in a range of 3-5% with respect to the composition, and the at least one surfactant has a weight percentage in a range of 35-60% with respect to the composition. In another embodiment of the present disclosure, the at least one water-insoluble component has a weight percentage in a range of 2.6-3.9% with respect to the composition, and the at least one polymer has a weight percentage in a range of 2-3.5% with respect to the composition, and the at least one electrolyte has a weight percentage in a range of 3-4% with respect to the composition, and the at least one surfactant has a weight percentage in a range of 35-60% with respect to the composition. # [0039] In an embodiment of the present disclosure, there is provided a liquid pre-mix composition as described herein, wherein the at least one surfactant is selected from a group consisting of anionic surfactant, amphoteric surfactant, non-ionic surfactant, and combinations thereof.#
[0040] In an embodiment of the present disclosure, there is provided a liquid pre-mix composition as described herein, wherein the at least one surfactant is selected from a group consisting of anionic surfactant, amphoteric surfactant, non-ionic surfactant, and combinations thereof, and wherein the anionic surfactant is selected from a group consisting of sodium lauryl ether sulfate, sodium lauroyl sarcosinate, disodium laureth sulfosuccinate, acyl isethionates, sodium cocoyl isethionate, sodium isethionate, sodium lauroyl isethionate, sodium lauroyl methyl isethionate, sodium methyl cocoyl taurate, and their series, sodium alkyl sulfate, alkyl sulfates, anionic acyl sarcosinates, methyl acyl taurates, N-acyl glutamates, acyl isethionates,

alkyl ether sulfates, alkyl sulfosuccinates, alkyl phosphate esters, ethoxylated alkyl phosphate esters, trideceth sulfates, protein condensates, mixtures of ethoxylated alkyl sulfates, and combinations thereof, the amphoteric surfactant is selected from a group consisting of cocamidopropyl betaine, coco dimethyl amine (CDMA), sodium dodecylaminopropionate, sodium 3-dodecylaminopropane sulfonate, high alkyl betaines including coco dimethyl carboxymethyl betaine, lauryl dimethyl carboxymethyl betaine, lauryl dimethyl alpha-carboxyethyl betaine, cetyl dimethyl carboxymethyl betaine, lauryl bis-(2-hydroxyethyl)carboxy methyl betaine, stearyl bis-(2-hydroxypropyl)carboxymethyl betaine, oleyl dimethyl gamma-carboxypropyl betaine, lauryl bis-(2-hydro-xypropyl)alpha-carboxyet-hyl betaine, sulfobetaines including coco dimethyl sulfopropyl betaine, stearyl dimethyl sulfopropyl betaine, amido betaines, amidosulfobetaines, and combinations thereof, the non-ionic surfactant is selected from a group consisting of cocamide monoethanolamine, polyethylene glycol (PEG)- 40 hydrogenated castor oil, polysorbate 20, decyl glucoside, polyethylene glycol (PEG)- 7 glyceryl cocoate, glyceryl monohydroxystearate, isosteareth-2, trideceth-3, hydroxystearic acid, propylene glycol stearate, PEG-2 stearate, sorbitan monostearate, glyceryl laurate, laureth-2, lauramide monoethanolamine, decyl glucoside, PEG-7 glyceryl cocoate, and combinations thereof. In another embodiment of the present disclosure, the anionic surfactant is sodium lauryl ether sulphate, the amphoteric surfactant is cocamidopropyl betaine, and the non-ionic surfactant is cocamide monoethanolamine. In yet another embodiment of the present disclosure, the at least one surfactant is a combination of sodium lauryl ether sulphate, cocamidopropyl betaine, and cocamide monoethanolamine.#
[0041] In an embodiment of the present disclosure, there is provided a liquid pre-mix composition as described herein, wherein the at least one water-insoluble component is selected from a group consisting of ethylene glycol distearate, ethylene glycol monostearate, zinc oxide, titanium dioxide, mica, and combinations thereof, the at least one polymer is selected from a group consisting of acrylate copolymer, hydroxyethyl cellulose, , natural gums, cellulose, and combinations thereof, the at least one electrolyte is selected from a group consisting of sodium chloride,

potassium chloride, ammonium chloride, sodium citrate, and combinations thereof. In another embodiment of the present disclosure, the at least one water-insoluble component is ethylene glycol distearate, the at least one polymer is acrylate copolymer, and the at least one electrolyte is sodium chloride. [0042] In an embodiment of the present disclosure, there is provided a liquid pre-mix composition comprising: (a) at least one water-insoluble component; (b) at least one polymer; (c) at least one electrolyte; (d) at least one surfactant; (e) water; and (f) at least one excipient selected from a group consisting of humectant, chelating agent, preservative, antioxidant, pH modifier, fragrance, and combinations thereof, wherein water has a weight percentage in a range of 25-40% with respect to the composition.# [0043] In an embodiment of the present disclosure, there is provided a liquid pre-mix composition comprising: (a) at least one water-insoluble component; (b) at least one polymer; (c) at least one electrolyte; (d) at least one surfactant; (e) water; and (f) at least one excipient selected from a group consisting of humectant, chelating agent, preservative, antioxidant, pH modifier, fragrance, and combinations thereof, wherein water has a weight percentage in a range of 25-40% with respect to the composition, and wherein the humectant is selected from a group consisting of glycerine, propylene glycol, sorbitol, polyethylene glycol, and combinations thereof, the chelating agent is selected from a group consisting of tetrasodium EDTA, sodium etidronate, disodium EDTA and combinations thereof.#
[0044] In an embodiment of the present disclosure, there is provided a liquid pre-mix composition as described herein, wherein the at least one water-insoluble component is ethylene glycol distearate (EGDS), the at least one polymer is acrylate copolymer, the at least one electrolyte is sodium chloride, the at least one surfactant is a combination of SLES, CMEA, and CAPB.#
[0045] In an embodiment of the present disclosure, there is provided a process for preparing a liquid pre-mix composition comprising: (a) at least one water-insoluble component; (b) at least one polymer; (c) at least one electrolyte; (d) at least one surfactant; and (e) water, wherein water has a weight percentage in a range of 25-40% with respect to the composition, said process comprising: (i) obtaining at least one water-insoluble component; (ii) obtaining at least one polymer; (iii) obtaining at

least one electrolyte; (iv) obtaining at least one surfactant; and (v) contacting the at least one water-insoluble component, the at least one polymer, the at least one electrolyte, and the at least one surfactant, to obtain the composition. [0046] In an embodiment of the present disclosure, there is provided a process for preparing a liquid pre-mix composition comprising: (a) at least one water-insoluble component; (b) at least one polymer; (c) at least one electrolyte; (d) at least one surfactant; (e) water; (f) at least one excipient selected from a group consisting of humectant, chelating agent, preservative, antioxidant, pH modifier, fragrance, and combinations thereof, wherein water has a weight percentage in a range of 25-40% with respect to the composition, said process comprising: (i) obtaining at least one water-insoluble component; (ii) obtaining at least one polymer; (iii) obtaining at least one electrolyte; (iv) obtaining at least one surfactant; (v) obtaining the at least one excipient; and (vi) contacting the at least one water-insoluble component, the at least one polymer, the at least one electrolyte, the at least one surfactant, and the at least one excipient, to obtain the composition.
[0047] In an embodiment of the present disclosure, there is provided a process as described herein, wherein the at least one water-insoluble component has a weight percentage in a range of 2.5-4.5% with respect to the composition, and the at least one polymer has a weight percentage in a range of 0.12-4.5% with respect to the composition, and the at least one electrolyte has a weight percentage in a range of 3-5% with respect to the composition, and the at least one surfactant has a weight percentage in a range of 35-60% with respect to the composition.# [0048] In an embodiment of the present disclosure, there is provided a process as described herein, wherein the at least one water-insoluble component is selected from a group consisting of ethylene glycol distearate, ethylene glycol monostearate, zinc oxide, titanium dioxide, mica, and combinations thereof, and combinations thereof, the at least one polymer is selected from a group consisting of acrylate copolymer, hydroxyethyl cellulose, natural gums, cellulose, and combinations thereof, the at least one electrolyte is selected from a group consisting of sodium chloride, potassium chloride, ammonium chloride, sodium citrate, and combinations thereof.#

[0049] In an embodiment of the present disclosure, there is provided a process as described herein, wherein the at least one water-insoluble component to the at least one electrolyte has a weight ratio in a range of 1:2-2:1, and the least one water-insoluble component to the at least one polymer has a weight ratio in a range of 1:2-38:1, and the at least one water-insoluble component to the at least one surfactant has a weight ratio in a range of 0.12:1-0.04:1.#
[0050] In an embodiment of the present disclosure, there is provided a process for preparing a liquid pre-mix composition comprising: (a) at least one water-insoluble component; (b) at least one polymer; (c) at least one electrolyte; (d) at least one surfactant selected from a group consisting of anionic surfactant, amphoteric surfactant, non-ionic surfactant, and combinations thereof; (e) water; and (f) excipient selected from a group consisting of humectant, chelating agent, preservative, antioxidant, fragrance, and combinations thereof, wherein water has a weight percentage in a range of 25-40% with respect to the composition, said process comprising: (i) contacting a combination of the at least one surfactant at a temperature in a range of 70-74È W`c R eZ^V aVcZ`U `W 30-40 minutes with a stirring at a range of 50-100 rpm, to obtain a first mixture, wherein the at least one surfactant comprises a combination of anionic surfactant and amphoteric surfactant; (ii) contacting the at least one water-insoluble component, the chelating agent, and the non-ionic surfactant, at a temperature in a range of 75-74È, e` `SeRZ_ R dVT`_U mixture; (iii) contacting the first mixture and the second mixture at a temperature in a range of 70-7/È hZeY deZccZ_X Z_ R cR_XV `W 4/-100 rpm for a time period of 10-20 minutes, to obtain a third mixture; (iv) contacting the third mixture and the at least one polymer at a temperature in a range of 65-64È hZeY deZccZ_X Z_ R cR_XV `W 4/-100 rpm for a time period of 5-15 minutes, to obtain a fourth mixture; (v) contacting the fourth mixture to the preservative, the antioxidant, the humectant, fragrance, at a temperature in a range of 40-34È hZeY deZccZ_X Z_ R cR_XV `W 4/-80 rpm for a time period of 5-15 minutes, to obtain a fifth mixture; (vi) contacting the fifth mixture to the at least one electrolyte at a temperature in a range of 35-3/È hZeY deZccZ_X Z_ R range of 40-60 rpm for a time period of 15-25 minutes, to obtain the composition. In another embodiment of the present disclosure, contacting a combination of the at

least one surfactant is at a temperature in a range of 75-7/È W`c R eZ^V aVcZ`U `W 21-38 minutes with a stirring at a range of 60-90 rpm, contacting the at least one water-insoluble component, the chelating agent, and the non-ionic surfactant, is done at a temperature in a range of 80-74È, e` `SeRZ_ R dVT`_U ^ZiefcV, contacting the first mixture and the second mixture at a temperature in a range of 73-67È hZeY deZccZ_X in a range of 60-90 rpm for a time period of 12-18 minutes, to obtain a third mixture, contacting the third mixture and the at least one polymer at a temperature in a range of 68-61È hZeY deZccZ_X Z_ R cR_XV `W 5/-90 rpm for a time period of 7-12 minutes, to obtain a fourth mixture, contacting the fourth mixture to the preservative, the antioxidant, the humectant, fragrance, is done at a temperature in a range of 40-34È with stirring in a range of 60-70 rpm for a time period of 7-12 minutes, to obtain a fifth mixture, and contacting the fifth mixture to the at least one electrolyte is done at a temperature in a range of 35-3/È hZeY deZccZ_X Z_ R cR_XV `W 30-60 rpm for a time period of 18-22 minutes.#
[0051] In an embodiment of the present disclosure, there is provided a ready-to-use product obtained from dilution of the composition comprising: (a) at least one water-insoluble component; (b) at least one polymer; (c) at least one electrolyte; (d) at least one surfactant selected from a group consisting of anionic surfactant, amphoteric surfactant, non-ionic surfactant, and combinations thereof; (e) water; and (f) excipient selected from a group consisting of humectant, chelating agent, preservative, antioxidant, fragrance, and combinations thereof, wherein water has a weight percentage in a range of 25-40% with respect to the composition, and wherein the composition is diluted with water in a range of 200-300% with respect to the composition.
[0052] In an embodiment of the present disclosure, there is provided a ready-to-use product obtained from dilution of the composition comprising: (a) at least one water-insoluble component; (b) at least one polymer; (c) at least one electrolyte; (d) at least one surfactant selected from a group consisting of anionic surfactant, amphoteric surfactant, non-ionic surfactant, and combinations thereof; (e) water; and (f) excipient selected from a group consisting of humectant, chelating agent, preservative, antioxidant, fragrance, and combinations thereof, wherein water has a

weight percentage in a range of 25-40% with respect to the composition, and wherein the composition is diluted with water in a range of 200-300% with respect to the composition, and wherein the product has a viscosity in a range of 800-3000 cps. [0053] In an embodiment of the present disclosure, there is provided a ready-to-use product obtained from dilution of the composition comprising: (a) at least one water-insoluble component; (b) at least one polymer; (c) at least one electrolyte; (d) at least one surfactant selected from a group consisting of anionic surfactant, amphoteric surfactant, non-ionic surfactant, and combinations thereof; (e) water; and (f) excipient selected from a group consisting of humectant, chelating agent, preservative, antioxidant, fragrance, and combinations thereof, wherein water has a weight percentage in a range of 25-40% with respect to the composition, and wherein the composition is diluted with water in a range of 200-300% with respect to the composition, and wherein the anionic surfactant has a weight percentage in a range of 4 to 6.5% with respect to the product.
[0054] Although the subject matter has been described in considerable detail with reference to certain examples and implementations thereof, other implementations are possible.
EXAMPLES
[0055] The disclosure will now be illustrated with working examples, which is intended to illustrate the working of disclosure and not intended to take restrictively to imply any limitations on the scope of the present disclosure. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood to one of ordinary skill in the art to which this disclosure belongs. Although methods and materials similar or equivalent to those described herein can be used in the practice of the disclosed methods and compositions, the exemplary methods, devices and materials are described herein. It is to be understood that this disclosure is not limited to particular methods, and experimental conditions described, as such methods and conditions may apply.

[0056] The present disclosure is supported by working and non-working examples as stated in the succeeding sections. Also, the criticality with respect to the weight percentages of the ingredients has been established by way of these examples.
Example and Observations
Example 1 - Working and Non-Working Examples
[0057] As depicted in the present Examples, SLES 1EO (Sodium lauryl ether sulphate) is an anionic surfactant, CMEA (cocamide monoethanolamine) is a non-ionic surfactant, CAPB (cocamidopropyl betaine) is an amphoteric surfactant. The water-insoluble component is a pearlizing agent - EGDS (ethylene glycol distearate). Tetrasodium EDTA is a chelating agent, glycerine is a humectant, sodium chloride is an electrolyte.
[0058] Polymer used was either hydroxyethylcellulose or acrylate copolymer. [0059] Process for preparing the composition of the present disclosure: [0060] Step 1: a combination of the at least one surfactant was contacted at a temperature in a range of 70-85°C for a time period of 30-40 minutes with a stirring at a range of 50-100 rpm, to obtain a first mixture, wherein the at least one surfactant comprises a combination of anionic surfactant and amphoteric surfactant. [0061] Step 2: the at least one water-insoluble component, the chelating agent, and the non-ionic surfactant was contacted at a temperature in a range of 75-85°C, to obtain a second mixture.
[0062] Step 3: the first mixture of step 1 and the second mixture of step 2 was contacted at a temperature in a range of 70-80°C with stirring in a range of 50-100 rpm for a time period of 10-20 minutes, to obtain a third mixture. [0063] Step 4: the third mixture and the at least one polymer was contacted at a temperature in a range of 65-75°C with stirring in a range of 50-100 rpm for a time period of 5-15 minutes, to obtain a fourth mixture.
[0064] Step 5: the fourth mixture was contacted to the preservative, the antioxidant, the humectant, fragrance, at a temperature in a range of 40-45°C with stirring in a range of 50-80 rpm for a time period of 5-15 minutes, to obtain a fifth mixture.

[0065] Step 6: the fifth mixture was contacted to the at least one electrolyte at temperature in a range of 35-3/È with stirring in a range of 40-60 rpm for a tim period of 15-25 minutes, to obtain the composition.
[0066] Table 1 depicts certain working and non-working examples of the produc of the present disclosure. Table 2 depicts the non-working examples. All th Working and Non-Working Examples depicted in Table 1 and Table 2 were prepare using the same process as disclosed previously. Table 1:

be of pearly opaque white appearance, the product should be stable, and the viscosity
post dilution should be in a range of 800-3000 cps.
[0068] As can be observed from Table 1 and 2, Working Example A has weight
percentages of the water-insoluble component, surfactant, polymer, and electrolyte
inside the disclosed ranges of respective ingredients. Therefore, it can be inferred
that the Working Example A is providing desired results of pearly opaque white
appearance, stability, and post diluting viscosity.
[0069] Non-Working Example B has a weight percentage of surfactants below the
range of 35-60% with respect to the composition. The weight percentage of
surfactants in Non-Working Example B is (70% of 18) + (2.3) + (5) = 19.9% with
respect to the composition which is lower than the desirable range. Also, water is
above the weight percentage range of 25-40% with respect to the composition.
Therefore, the composition does not provide the desirable attribute of stability and
viscosity.
[0070] Non-Working Example C has a weight percentage of EGDS lesser than that
of the disclosed range, and also has water above than the working weight percentage
range, therefore, the resulting composition has a translucent appearance
accompanied with low pearliness which is not desirable.
[0071] Non-Working Example D has EGDS weight percentage higher than the
working range, therefore, the resulting composition is not up to the mark with respect
to stability.
[0072] Non-Working Example E has electrolyte weight percentage below the
working range and on the other hand polymer and water are present above the weight
percentage. Therefore, the resulting composition does not satisfy the parameters of
stability and post-dilution viscosity and hence is a Non-Working Example.
[0073] Non-Working Example F has electrolyte and polymer weight percentage
higher than the disclosed range. Therefore, it can be inferred that because of these
alternate weight percentages the resulting composition is not desirable in terms of
appearance and stability.

diluting); manufactured by competitors procured from the market. [0076] ITC prototype 1 and 2 refers to the ready-to-use product of the present disclosure and they have been compared with the market sample 1 and 2. ITC prototype are ready-to-use product prepared using 50 ml of the pre-mix composition of the present disclosure diluted with 150 ml of water. It can be observed that in spite of the lower amount of total surfactant active present in the prototypes they are able to show sensorial features in terms of appearance at par with the commercial products.
Example 3
Viscosity change with respect to dilution
[0077] The present example depicts the kinetics of change in viscosity with respect
to the dilution. Table 4 depicts the viscosity change with respect to the percentage
dilution. Figure 1 is an illustrative graph depicting the kinetics of change in viscosity
as depicted in Table 4.
Table 4:

[0078] It can be appreciated that, upon diluting the composition of the present disclosure, the viscosity is gradually decreased. Referring to Table 4 and Figure 1, the drop in the viscosity is only from 4500 to 2450 cps from 100% to 280% dilution. But, beyond 300%, the viscosity is decreased very rapidly. In case of 320% dilution, the viscosity is 1650, and it decreases to 220 cps and 200 cps for 360% and 400% dilution respectively. Therefore, it can be said that the composition of the present disclosure can resist a sharp change in viscosity upon dilution to the factor of 200-300%. Thus, it will provide appropriate sensorial appeal to the consumers even if the consumers end up diluting the composition more than that required. [0079] Overall, it can be observed that the weight percentage ranges of the ingredients of water, water-insoluble agent, surfactant, polymer, and electrolyte are critical for obtaining a liquid pre-mix composition with desirable parameters of appearance and stability. The non-working examples clearly depict that stability is getting affected if the deviation from weight percentage ranges for water, and other critical components is made. Also, the weight percentage ranges are critical to ensure that desirable viscosity is achieved after diluting the pre-mix composition. Another critical parameter of the present disclosure can be attributed to the ease of dilution the pre-mix offers to the consumers ensuring a gradual change in viscosity, thereby preserving the sensorial attribute.
Advantages of the present disclosure
[0080] The present disclosure discloses a liquid pre-mix composition and a process
for obtaining the composition. Also disclosed is a ready-to-use diluted product

obtained from the dilution of the pre-mix composition. Advantages of the present disclosure is in terms of the uniform viscosity of the pre-mix composition and a larger operating window for dilution of the pre-mix composition. This means that even if consumers add a bit of extra water while diluting the pre-mix composition, the viscosity will not get drastically affected, and thus providing the required aesthetic feel to the consumers. Also, the pre-mix composition of the present disclosure achieves a high content of water-insoluble component (2.5-4.5%) in 25-40% of water with respect to the composition, and a significant advantage being that such a composition after dilution provides gradual change in viscosity which is sensorially acceptable to the consumers. The ready-to-use product obtained from dilution also performs at par with the market product in spite of containing lesser Total Active Surfactant Content. The pre-mix composition maintains stability and a desirable appearance of being white opaque pearly.

1. A liquid pre-mix composition comprising:
a) at least one water-insoluble component;
b) at least one polymer;
c) at least one electrolyte;
d) at least one surfactant; and
e) water,
wherein water has a weight percentage in a range of 25-40% with respect to the composition.
2. The composition as claimed in claim 1, wherein the at least one water-insoluble component to the at least one electrolyte has a weight ratio in a range of 1:2-2:1.
3. The composition as claimed in claim 1, wherein the least one water-insoluble component to the at least one polymer has a weight ratio in a range of 1:2-38:1.
4. The composition as claimed in claim 1, wherein the at least one water-insoluble component to the at least one surfactant has a weight ratio in a range of 0.12:1-0.04:1.5.
5. The composition as claimed in claim 1, wherein the composition has a viscosity in a range of 5500-8500 cps.
6. The composition as claimed in claim 1, wherein the at least one water-insoluble component has a weight percentage in a range of 2.5-4.5% with respect to the composition.

7. The composition as claimed in claim 6, wherein the at least one water-insoluble component has a weight percentage in a range of 2.6-3.9% with respect to the composition.
8. The composition as claimed in claim 1, wherein the at least one polymer has a weight percentage in a range of 0.12-4.5% with respect to the composition.

9. The composition as claimed in claim 1, wherein the at least one electrolyte
has a weight percentage in a range of 3-5% with respect to the
composition.
10. The composition as claimed in claim 1, wherein the at least one surfactant has a weight percentage in a range of 35-60% with respect to the composition.
11. The composition as claimed in claim 1, wherein the at least one surfactant is selected from a group consisting of anionic surfactant, amphoteric surfactant, non-ionic surfactant, and combinations thereof.
12. The composition as claimed in claim 11, wherein the anionic surfactant is selected from a group consisting of sodium lauryl ether sulfate, sodium lauroyl sarcosinate, disodium laureth sulfosuccinate, acyl isethionates, sodium cocoyl isethionate, sodium isethionate, sodium lauroyl isethionate, sodium lauroyl methyl isethionate, sodium methyl cocoyl taurate, sodium alkyl sulfate, alkyl sulfates, anionic acyl sarcosinates, methyl acyl taurates, N-acyl glutamates, acyl isethionates, alkyl ether sulfates, alkyl sulfosuccinates, alkyl phosphate esters, ethoxylated alkyl phosphate esters, trideceth sulfates, protein condensates, mixtures of ethoxylated alkyl sulfates, and combinations thereof; the amphoteric surfactant is selected from a group consisting of cocamidopropyl betaine (CAPB), coco dimethyl amine (CDMA), sodium dodecylaminopropionate, sodium 3-dodecylaminopropane sulfonate, high alkyl betaines including coco dimethyl carboxymethyl betaine, lauryl dimethyl carboxymethyl betaine, lauryl dimethyl alpha-carboxyethyl betaine, cetyl dimethyl carboxymethyl betaine, lauryl bis-(2-hydroxyethyl)carboxy methyl betaine, stearyl bis-(2-hydroxypropyl)carboxymethyl betaine, oleyl dimethyl gamma-carboxypropyl betaine, lauryl bis-(2-hydro-xypropyl)alpha-carboxyet-hyl betaine, sulfobetaines, stearyl dimethyl sulfopropyl betaine, amido betaines, amidosulfobetaines, and combinations thereof, the non-ionic surfactant is selected from a group consisting of cocamide

monoethanolamine (CMEA), polyethylene glycol (PEG)- 40 hydrogenated castor oil, polysorbate 20, decyl glucoside, polyethylene glycol (PEG)- 7 glyceryl cocoate, glyceryl monohydroxystearate, isosteareth-2, trideceth-3, hydroxystearic acid, propylene glycol stearate, PEG-2 stearate, sorbitan monostearate, glyceryl laurate, laureth-2, lauramide monoethanolamine, decyl glucoside, PEG-7 glyceryl cocoate, and combinations thereof.
13. The composition as claimed in claim 1, wherein the at least one water-insoluble component is selected from a group consisting of ethylene glycol distearate, ethylene glycol monostearate, zinc oxide, titanium dioxide, mica, and combinations thereof, the at least one polymer is selected from a group consisting of hydroxyethyl cellulose, acrylate copolymer, natural gums, cellulose, and combinations thereof, the at least one electrolyte is selected from a group consisting of sodium chloride, potassium chloride, ammonium chloride, sodium citrate, and combinations thereof.
14. The composition as claimed in claim 1, wherein the composition further comprises at least one excipient selected from a group consisting of humectant, chelating agent, preservative, antioxidant, pH modifier, fragrance, and combinations thereof.
15. A process for preparing the composition as claimed in claim 1, said process comprising:

a) obtaining at least one water-insoluble component;
b) obtaining at least one polymer;
c) obtaining at least one electrolyte;
d) obtaining at least one surfactant; and
e) contacting the at least one water-insoluble component, the at least one polymer, the at least one electrolyte, and the at least one surfactant, to obtain the composition.
16. A process for preparing the composition as claimed in claim 14, said
process comprising:

a) obtaining at least one water-insoluble component;
b) obtaining at least one polymer;
c) obtaining at least one electrolyte;
d) obtaining at least one surfactant;
e) obtaining at least one excipient; and
f) contacting the at least one water-insoluble component, the at least one polymer, the at least one electrolyte, the at least one surfactant, and the at least one excipient, to obtain the composition.
7. A process for preparing a liquid pre-mix composition comprising: (a) at least one water-insoluble component; (b) at least one polymer; (c) at least one electrolyte; (d) at least one surfactant selected from a group consisting of anionic surfactant, amphoteric surfactant, non-ionic surfactant, and combinations thereof; (e) water; and (f) excipient selected from a group consisting of humectant, chelating agent, preservative, antioxidant, fragrance, and combinations thereof, wherein water has a weight percentage in a range of 25-40% with respect to the composition, said process comprising: (i) contacting a combination of the at least one surfactant at a temperature in a range of 70-85°C for a time period of 30-40 minutes with a stirring at a range of 50-100 rpm, to obtain a first mixture, wherein the at least one surfactant comprises a combination of anionic surfactant and amphoteric surfactant; (ii) contacting the at least one water-insoluble component, the chelating agent, and the non-ionic surfactant, at a temperature in a range of 75-85°C, to obtain a second mixture; (iii) contacting the first mixture and the second mixture at a temperature in a range of 70-80°C with stirring in a range of 50-100 rpm for a time period of 10-20 minutes, to obtain a third mixture; (iv) contacting the third mixture and the at least one polymer at a temperature in a range of 65-75°C with stirring in a range of 50-100 rpm for a time period of 5-15 minutes, to obtain a fourth mixture; (v) contacting the fourth mixture to the preservative, the antioxidant, the humectant, fragrance, at a temperature in a range of 40-45°C with stirring in a range

of 50-80 rpm for a time period of 5-15 minutes, to obtain a fifth mixture; (vi) contacting the fifth mixture to the at least one electrolyte at a temperature in a range of 35-3/È with stirring in a range of 40-60 rpm for a time period of 15-25 minutes, to obtain the composition.
18. The process as claimed in claim 17, wherein the at least one water-insoluble component is selected from a group consisting of ethylene glycol distearate, ethylene glycol monostearate, zinc oxide, titanium dioxide, mica, and combinations thereof, the at least one polymer is selected from a group consisting of hydroxyethyl cellulose, acrylate copolymer, natural gums, cellulose, and combinations thereof, the at least one electrolyte is selected from a group consisting of sodium chloride, potassium chloride, ammonium chloride, sodium citrate, and combinations thereof.
19. The process as claimed in claim 17, wherein the at least one water-insoluble component has a weight percentage in a range of 2.5-4.5% with respect to the composition, the at least one polymer has a weight percentage in a range of 0.12-4.5% with respect to the composition, the at least one electrolyte has a weight percentage in a range of 3-5% with respect to the composition, and the at least one surfactant has a weight percentage in a range of 35-60% with respect to the composition.
20. A ready-to-use product obtained from dilution of the composition as claimed in claim 1, wherein the composition is diluted with water in a range of 200-300% with respect to the composition.
21. The ready-to-use product as claimed in claim 20, wherein the product has a viscosity in a range of 800-3000 cps.
22. The ready-to-use product as claimed in claim 20, wherein the product comprises a total active surfactant content in a range of 7.5 to 8.4% with respect to the product.