Abstract: he present disclosure provides solution to the problems involved in determining the crystallinity of sirolimus. More particularly, the instant disclosure is successful in providing a method to determine crystallinity of sirolimus or its analogues using Near-Infrared [NIR] spectroscopy. Also, the instant disclosure provides a method for crystallization of sirolimus or its analogues.
he present invention relates to an assay method to determine crystallinity of sirolimus or analog of sirolimus. The present invention also relates to use of this assay method to predict stability of sirolimus or analog of sirolimus. The invention also relates to a process for preparation of stable form of sirolimus or analog of sirolimus.
| # | Name | Date |
|---|---|---|
| 1 | Form-5.pdf | 2011-09-02 |
| 2 | Form-3.pdf | 2011-09-02 |
| 3 | Form-1.pdf | 2011-09-02 |
| 4 | Drawings.pdf | 2011-09-02 |
| 5 | 136-CHE-2009 FORM-13 13-07-2012.pdf | 2012-07-13 |
| 6 | 136-CHE-2009 FORM-1 13-07-2012.pdf | 2012-07-13 |
| 7 | 136-CHE-2009 CORRESPONDENCE OTHERS 13-07-2012.pdf | 2012-07-13 |
| 8 | 136-CHE-2009 FORM-3 09-05-2014.pdf | 2014-05-09 |
| 9 | 136-CHE-2009 CORRESPONDENCE OTHERS 09-05-2014.pdf | 2014-05-09 |
| 10 | Response_IP10955.pdf | 2014-11-24 |
| 11 | IP19055 Form 3, Petition & corresponding Office Action.pdf | 2014-11-24 |
| 12 | IP19055 Amended claims marked & clear version.pdf | 2014-11-24 |
| 13 | IP19055 Amended Abstract marked & clear version.pdf | 2014-11-24 |
| 14 | IP10955 petition.pdf | 2014-11-24 |
| 15 | IP10955 Form 3.pdf | 2014-11-24 |
| 16 | IP10955 Enclosures.pdf | 2014-11-24 |
| 17 | IP10955 COMPLETE SPEC.pdf | 2014-11-24 |
| 18 | 136-CHE-2009 POWER OF ATTORNEY 25-11-2014.pdf | 2014-11-25 |
| 19 | 136-CHE-2009 CORRESPONDENCE OTHERS 25-11-2014.pdf | 2014-11-25 |
| 20 | 136-CHE-2009_EXAMREPORT.pdf | 2016-07-02 |
| 21 | Other Document [01-12-2016(online)].pdf | 2016-12-01 |
| 22 | Form 13 [01-12-2016(online)].pdf | 2016-12-01 |
| 23 | Form 27_License_15-03-2017.pdf | 2017-03-15 |
| 24 | Correspondence by Applicant_Form 27_15-03-2017.pdf | 2017-03-15 |
| 25 | Form27_Licence_13-03-2018.pdf | 2018-03-13 |
| 26 | Form27_Authorization Letter_13-03-2018.pdf | 2018-03-13 |
| 27 | Correspondence by Applicant_Form27_13-03-2018.pdf | 2018-03-13 |
| 28 | 136-CHE-2009-RELEVANT DOCUMENTS [25-08-2018(online)].pdf | 2018-08-25 |
| 29 | 136-CHE-2009-Changing Name-Nationality-Address For Service [25-08-2018(online)].pdf | 2018-08-25 |
| 30 | Correspondence by Agent_Form 13_28-08-2018.pdf | 2018-08-28 |
| 31 | Form 27_Licence_25-03-2019.pdf | 2019-03-25 |
| 32 | 136-CHE-2009- Form 27_Licence_20-03-2020.pdf | 2020-03-20 |
| 33 | 267759-Form 27_Statement of Working_23-09-2021.pdf | 2021-09-23 |
| 34 | 267759-Form 27_Statement of working_28-09-2022.pdf | 2022-09-28 |
| 35 | 267759.Form27.pdf | 2023-11-08 |