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A Method For Extraction Of Fractions Containing Pharmacologically Active Ingredients With Less Cytotoxicity From One Or More Plants

Abstract: The invention describes a method of extraction from Withania somnifera (WS) and one or more fractions containing the pharmacologically active ingredients extracted from WS using the method of extraction. A fraction predominantly includes Withaferin-A along with other pharmacologically active ingredients of WS. Another fraction includes additional pharmacologically active ingredients of WS. The method includes soaking a plant material of WS in a mixture of aqueous alcohol and chloroform for a pre¬determined time period and then filtering the mixture to obtain a multi-layered filtrate and a first residue. Thereafter, the multi-layered filtrate is separated into an aqueous alcohol layer and a chloroform layer, Subsequently, the method includes concentrating the aqueous alcohol layer and chloroform layer by evaporation to obtain a hydro-alcoholic fraction and a chloroform fraction. The method further includes dissoluting the chloroform fraction in hexane to get a hexane soluble fraction and a second residue. The second residue obtained by the above method constitutes the fraction including predominantly Withaferin A along with other pharmacologically active ingredients of WS. The hydro-alcoholic fraction obtained by the above method constitutes another fraction including additional pharmacologically active ingredients of WS.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
22 May 2009
Publication Number
48/2010
Publication Type
INA
Invention Field
TRADITIONAL KNOWLEDGE CHEMICAL
Status
Email
Parent Application

Applicants

BIO-VED PHARMACEUTICALS PVT LTD
'BAIF' BHAVAN Z WING, DR. MANIBHAI DESAI NAGAR, WARJE MALWADI, PUNE-411052, INDIA.

Inventors

1. CHITRE DEEPA
'BAIF' BHAVAN Z WING, DR. MANIBHAI DESAI NAGAR, WARJE MALWADI, PUNE-411052, INDIA.
2. DEY DEBEN
'BAIF' BHAVAN Z WING, DR. MANIBHAI DESAI NAGAR, WARJE MALWADI, PUNE-411052, INDIA.

Specification

FORM 2 THE PATENTS ACT, 1970 {39 of 1970) & THE PATENTS RULES, 2003 PROVISIONAL SPECIFICATION [See section 10 and rule 13] Title: A METHOD FOR EXTRACTION OF FRACTIONS CONTAINING PHARMACOLOGICALLY ACTIVE INGREDIENTS WITH LESS CYTOTOXICITY FROM ONE OR MORE PLANTS 2. APPLICANT: (a) NAME : BIO-VED Pharmaceuticals, Pvt. Ltd. (b) NATIONALITY : Indian

Documents

Orders

Section Controller Decision Date

Application Documents

# Name Date
1 1284-MUM-2009-ABSTRACT(21-5-2010).pdf 2018-08-10
1 1284-MUM-2009-CORRESPONDENCE(IPO)-(FER)-(26-11-2012).pdf 2012-11-26
2 1284-MUM-2009-ABSTRACT(22-5-2009).pdf 2018-08-10
2 1284-MUM-2009-SPECIFICATION(AMENDED)-(25-11-2013).pdf 2013-11-25
3 1284-MUM-2009-REPLY TO EXAMINATION REPORT(25-11-2013).pdf 2013-11-25
3 1284-mum-2009-abstract.doc 2018-08-10
4 1284-MUM-2009-PETITION UNDER RULE-137(25-11-2013).pdf 2013-11-25
4 1284-mum-2009-abstract.pdf 2018-08-10
5 1284-MUM-2009-OTHER DOCUMENT(25-11-2013).pdf 2013-11-25
5 1284-MUM-2009-CLAIMS(21-5-2010).pdf 2018-08-10
6 1284-MUM-2009-FORM PCT-ISA-237(25-11-2013).pdf 2013-11-25
6 1284-MUM-2009-CORRESPONDENCE(21-5-2010).pdf 2018-08-10
7 1284-MUM-2009-FORM PCT-IB-373(25-11-2013).pdf 2013-11-25
7 1284-MUM-2009-CORRESPONDENCE(24-7-2009).pdf 2018-08-10
8 1284-MUM-2009-FORM 3(25-11-2013).pdf 2013-11-25
8 1284-MUM-2009-CORRESPONDENCE(IPO)-(7-10-2009).pdf 2018-08-10
9 1284-MUM-2009-CORRESPONDENCE(IPO)-(DECISION)-(28-3-2016).pdf 2018-08-10
9 1284-MUM-2009-FORM 1(25-11-2013).pdf 2013-11-25
10 1284-MUM-2009-CLAIMS(AMENDED)-(25-11-2013).pdf 2013-11-25
10 1284-MUM-2009-CORRESPONDENCE(IPO)-(HEARING NOTICE)-(1-3-2016).pdf 2018-08-10
11 1284-MUM-2009-ABSTRACT(25-11-2013).pdf 2013-11-25
11 1284-mum-2009-correspondence.pdf 2018-08-10
12 1284-MUM-2009-CORRESPONDENCE-(30-03-2016).pdf 2016-03-30
12 1284-MUM-2009-DESCRIPTION(COMPLETE)-(21-5-2010).pdf 2018-08-10
13 1284-MUM-2009_EXAMREPORT.pdf 2018-08-10
14 1284-mum-2009-description(provisional).pdf 2018-08-10
14 1284-mum-2009-form 5.pdf 2018-08-10
15 1284-MUM-2009-DRAWING(21-5-2010).pdf 2018-08-10
15 1284-MUM-2009-FORM 5(24-7-2009).pdf 2018-08-10
16 1284-MUM-2009-FORM 1(24-7-2009).pdf 2018-08-10
16 1284-MUM-2009-FORM 5(22-5-2009).pdf 2018-08-10
17 1284-mum-2009-form 3.pdf 2018-08-10
17 1284-mum-2009-form 1.pdf 2018-08-10
18 1284-mum-2009-form 26.pdf 2018-08-10
18 1284-MUM-2009-FORM 18(21-5-2010).pdf 2018-08-10
19 1284-mum-2009-form 2(21-5-2010).pdf 2018-08-10
19 1284-mum-2009-form 2.pdf 2018-08-10
20 1284-MUM-2009-FORM 2(TITLE PAGE)-(21-5-2010).pdf 2018-08-10
21 1284-MUM-2009-FORM 2(TITLE PAGE)-(PROVISIONAL)-(22-5-2009).pdf 2018-08-10
21 1284-mum-2009-form 2(title page).pdf 2018-08-10
22 1284-MUM-2009-FORM 2(TITLE PAGE)-(PROVISIONAL)-(22-5-2009).pdf 2018-08-10
22 1284-mum-2009-form 2(title page).pdf 2018-08-10
23 1284-MUM-2009-FORM 2(TITLE PAGE)-(21-5-2010).pdf 2018-08-10
24 1284-mum-2009-form 2(21-5-2010).pdf 2018-08-10
24 1284-mum-2009-form 2.pdf 2018-08-10
25 1284-mum-2009-form 26.pdf 2018-08-10
25 1284-MUM-2009-FORM 18(21-5-2010).pdf 2018-08-10
26 1284-mum-2009-form 1.pdf 2018-08-10
26 1284-mum-2009-form 3.pdf 2018-08-10
27 1284-MUM-2009-FORM 1(24-7-2009).pdf 2018-08-10
27 1284-MUM-2009-FORM 5(22-5-2009).pdf 2018-08-10
28 1284-MUM-2009-DRAWING(21-5-2010).pdf 2018-08-10
28 1284-MUM-2009-FORM 5(24-7-2009).pdf 2018-08-10
29 1284-mum-2009-description(provisional).pdf 2018-08-10
29 1284-mum-2009-form 5.pdf 2018-08-10
30 1284-MUM-2009_EXAMREPORT.pdf 2018-08-10
31 1284-MUM-2009-CORRESPONDENCE-(30-03-2016).pdf 2016-03-30
31 1284-MUM-2009-DESCRIPTION(COMPLETE)-(21-5-2010).pdf 2018-08-10
32 1284-mum-2009-correspondence.pdf 2018-08-10
32 1284-MUM-2009-ABSTRACT(25-11-2013).pdf 2013-11-25
33 1284-MUM-2009-CLAIMS(AMENDED)-(25-11-2013).pdf 2013-11-25
33 1284-MUM-2009-CORRESPONDENCE(IPO)-(HEARING NOTICE)-(1-3-2016).pdf 2018-08-10
34 1284-MUM-2009-CORRESPONDENCE(IPO)-(DECISION)-(28-3-2016).pdf 2018-08-10
34 1284-MUM-2009-FORM 1(25-11-2013).pdf 2013-11-25
35 1284-MUM-2009-CORRESPONDENCE(IPO)-(7-10-2009).pdf 2018-08-10
35 1284-MUM-2009-FORM 3(25-11-2013).pdf 2013-11-25
36 1284-MUM-2009-CORRESPONDENCE(24-7-2009).pdf 2018-08-10
36 1284-MUM-2009-FORM PCT-IB-373(25-11-2013).pdf 2013-11-25
37 1284-MUM-2009-FORM PCT-ISA-237(25-11-2013).pdf 2013-11-25
37 1284-MUM-2009-CORRESPONDENCE(21-5-2010).pdf 2018-08-10
38 1284-MUM-2009-OTHER DOCUMENT(25-11-2013).pdf 2013-11-25
38 1284-MUM-2009-CLAIMS(21-5-2010).pdf 2018-08-10
39 1284-MUM-2009-PETITION UNDER RULE-137(25-11-2013).pdf 2013-11-25
39 1284-mum-2009-abstract.pdf 2018-08-10
40 1284-MUM-2009-REPLY TO EXAMINATION REPORT(25-11-2013).pdf 2013-11-25
41 1284-MUM-2009-SPECIFICATION(AMENDED)-(25-11-2013).pdf 2013-11-25
41 1284-MUM-2009-ABSTRACT(22-5-2009).pdf 2018-08-10
42 1284-MUM-2009-CORRESPONDENCE(IPO)-(FER)-(26-11-2012).pdf 2012-11-26
42 1284-MUM-2009-ABSTRACT(21-5-2010).pdf 2018-08-10