A Method To Isolate Isokaempferide From Acalypha Alnifolia


Updated over 1 year ago

Abstract

Pharmaceutically potent flavone compound isokaempferide was isolated first time from Acalypha alnifolia by a method of column chromatography. Based on the solvent nature the crude extracts obtained from the plant leaf. The high polar solvent extracts gave better antioxidant and pharmacological activities which mainly coincident with secondary metabolites quantity. The acetone extract have focused for compound isolation because of its better activity than methanol extract in most of the experimental attempt. By the way acetone extract engaged through the column chromatography with sequential changes in mobile phase from low to high polar solvents. This successivemobile phase is lying behind the compoundseparation from the crude. The chloroform :ethylacetate fraction of silica gel column chromatography yields isokaempferide better from acetone extract of A. alnifolia. Though isokaempferide isolated previously from other sources this method of isolation from Acalypha alnifolia is the first effort and easily achievable.

Information

Application ID 4777/CHE/2015
Invention Field CHEMICAL
Date of Application 2015-09-09
Publication Number 39/2015

Applicants

Name Address Country Nationality
PONNUSAMY REVATHI DEPARTMENT OF BOTANY BHARATHIAR UNIVERSITY, MARUTHAMALAI MAIN ROAD, COIMBATORE - 641 046, India India
DR.THANGARAJ PARIMELAZHAGAN DEPARTMENT OF BOTANY BHARATHIAR UNIVERSITY, MARUTHAMALAI MAIN ROAD, COIMBATORE - 641 046, India India

Inventors

Name Address Country Nationality
PONNUSAMY REVATHI DEPARTMENT OF BOTANY BHARATHIAR UNIVERSITY, COIMBATORE - 641 046, India India
DR.THANGARAJ PARIMELAZHAGAN DEPARTMENT OF BOTANY BHARATHIAR UNIVERSITY, COIMBATORE - 641 046, India India

Specification

Documents

Name Date
4777-CHE-2015-Form 9-090915.pdf 2015-09-12
4777-CHE-2015-Form 18-090915.pdf 2015-09-12
4777-CHE-2015-Form 2(Title Page)-090915.pdf 2015-09-12
4777-CHE-2015-Form 1-090915.pdf 2015-09-12
4777-CHE-2015-FER.pdf 2019-05-22
Form2Title Page_Fer Reply_19-11-2019.pdf 2019-11-19
Markedup Claims and NBA Approval_Fer Reply_19-11-2019.pdf 2019-11-19
Form-3_Fer Reply_19-11-2019.pdf 2019-11-19
Drawing_Fer Reply_19-11-2019.pdf 2019-11-19
Claims_Fer Reply_19-11-2019.pdf 2019-11-19
Correspondence by Applicant_Reply to Examination Report_19-11-2019.pdf 2019-11-19
Abstract_Fer Reply_19-11-2019.pdf 2019-11-19
Amended Pages of Specification _Fer Reply_19-11-2019.pdf 2019-11-19
4777-CHE-2015-Marked Copy-Hearing Reply_12-10-2020.pdf 2020-10-12
4777-CHE-2015_Correspondence_Hearing Reply_12-10-2020.pdf 2020-10-12
4777-CHE-2015-Claims-Hearing Reply_12-10-2020.pdf 2020-10-12
4777-CHE-2015-IntimationOfGrant14-10-2020.pdf 2020-10-14
4777-CHE-2015-PatentCertificate14-10-2020.pdf 2020-10-14
4777-CHE-2015-US(14)-HearingNotice-(HearingDate-30-09-2020).pdf 2021-10-17
349229- Correspondence_Renewal Fee_09-12-2020.pdf 2020-12-09
4777-CHE-2015_Marked up Claims_Granted_349229_14-10-2020.pdf 2020-10-14
4777-CHE-2015_Drawings_Granted_349229_14-10-2020.pdf 2020-10-14
4777-CHE-2015_Description_Granted_349229_14-10-2020.pdf 2020-10-14
4777-CHE-2015_Claims_Granted_349229_14-10-2020.pdf 2020-10-14
4777-CHE-2015_Abstract_Granted_349229_14-10-2020.pdf 2020-10-14

Orders

Applicant Section Controller Decision Date URL