Claims
What is claimed is:
1. Inhaler contains the novel aroma composition which formulated from more than 100 medicinal and aromatic plants essential oil.
2. The novel aroma composition in Inhaler are used to improve the 'feel' or
'mood' of alocation, and are often used to either improve an original emotional response or aid in the development of a specific emotional response.
3. The novel aroma composition in Inhaler is used to improve the state of brain arousal, relaxation and alertness for Sympathomimetic therapeutic effect only through inhalation.
4. The novel aroma composition in Inhaler as claimed in Claim l,are used to record the change in brain"alpha-wave"by EEG after inhalation for 1 minute.
5. The record the change in brain"alpha-wave"by EEG after inhalation for 1 minute as claimed in Claim 4 used to treat several mental disorders, including loss of consciousness, mania, and emotional agitation, by The novel aroma composition in Inhaler.
6. The 1 minute inhalation from Inhaler composition for the treatment of several mental disorders as claimed in Claim 5 have penetrating aroma and stimulating quality, which act directly on brain and stimulates the limbic system of brain and could be used for the very severe cases of brain

disorder, especially when the person is losing consciousness or suffering from severe delirium.
7. The penetrating and stimulating quality of novel aroma composition in Inhaler as claimed in Claim 6 have provides an anti-stress agent which can effectively prevent or alleviate various symptoms caused by stress.
8. The novel aroma composition in Inhaler as claimed in Claim 1 to 8 is safe and non toxic and easily inhaled and saturates the nasal mucous membranes.

Description:
FIELD OF THE INVENTION
The present invention relates to a system and a method for the delivery of the blend of the essential oils describes as anti stress and anti hypertension in ancient ayurvedic text. The system and a method for the delivery of the blend of the essential oils are designated as stress buster inhaler. The inhaler comprise the delivering the bland of volatile essential oils by inhalation comprises a canister which comprises a body which includes a base and a head and defines a chamber containing volatile essential oils , and a valve stem which extends from the head of the body and from which medicament is in use delivered on actuation of the canister.
BACKGROUND OF THE INVENTION
In prior art inhalation device is well known in the art of inhalation devices. It is therefore not necessary to describe the construction and operation of a pMDI other than in bare essentials.
Medicinal herbs are significant source of pharmaceutical drugs. Herbalists and indigenous healers have used botanicals traditionally worldwide for the prevention and treatment of liver disease. Clinical research in this century has confirmed the efficacy of several plants in the treatment of many neurological disorders. In recent years many researchers have examined the effects of plant used traditionally by indigenous healers and herbalists to for support neurological function and treat the sexual disease. In most cases, research has confirmed traditional experience and wisdom by discovering the mechanisms and modes of

action of these plants as well as reaffirming the therapeutic effectiveness of certain plants in clinical studies.Many method of pharmaceutically managing various CNS disorders by inhaling the specific smell. To support the findings of our invention we are describing some facts which correlate the smell and brain function.
Smell is one of the chemical senses. Smells are detected in the nose by the specialized receptor cells of the olfactory epithelium. These are called olfactory receptor neurones.The respiratory and olfactory epithelial cells lining the structures of the internal nose have a very rich blood supply and are covered by watery mucus that is continually flowing into the back of the throat. In the roof of each nostril is a region called the nasal mucosa. This region contains the sensory epithelium - the olfactory epithelium - covered by mucus. The area of this olfactory region is 5cm in humans. The epithelium contains, as well as the sensory cells, Bowman's glands producing the secretion that bathes the surface of the receptors. This is an aqueous secretion containing muco polysaccharides, immunoglobulins, proteins (e.g. lysozyme) and various enzymes (e.g. peptidases). Chemicals detected by our sensory systems need to have certain properties. For instance, odour molecules must be small enough to be volatile (less than 300-400 relative molecular mass) so that they can vapourise, reach the nose and then dissolve in the mucus. Both behavioral and molecular studies point to a potentially important role of dopamine in olfaction. Parkinson's patients, who have reduced dopamine levels, also have impaired odour recognition. Injection of dopamine analogues reduces olfactory sensitivity in rats. Dopamine may play an important neuormodulatory role in olfaction by reducing transmitter release from ORNs .
Inhibitory circuits in the bulb have been found to be mediated by GABA and in vitro studies have shown interactions between GABA and glycine. Various drugs have been demonstrated to have an effect on the sense of smell.

(Figure Removed)

Olfactory receptor neuron (ORN) is shown in yellow. It has cilia that project from the dendritic knob into the mucus and on which the receptors for odorants are located. ORNs are embedded in the olfactory epithelium which has a number of other cell types; basal cells are stem cells for ORNs and other epithelial cells and supporting cells provide a glial-like function and may be involved in determining the composition of the mucus. The ORN has an axon that terminates in the olfactory bulb.
Olfaction and EEG
Electroencephalography (EEG) has been used to study olfaction. EEG can be used to monitor the state of brain arousal, relaxation and alertness. Fragrance manufacturers have for many years been trying to demonstrate that certain smells are relaxing. This can, in theory, be done using EEG. One of the brain-waves measured by EEG is called the "alpha-wave". It has a particular frequency of 8-12 Hz (or waves per sec). Increased alpha-wave activity in your brain is a sign of relaxation (more correctly speaking - a lower state of arousal, since you produce them when you are drowsy and just before you fall asleep). When the eyes are closed there is an increase in alpha waves in the occipital region (back of the head) where the visual cortex lies. The visual cortex is receiving less (no) information

and so therefore it "relaxes" In fact it locks onto an oscillatory activity (8-12Hz) thought to be generated in the thalamus. The frontal lobes produce alpha waves in response to relaxation (with the eyes open) and it has been demonstrated that the left front cortex responds to appetitive (pleasant) experience with a decrease in alpha activity. Pleasant experiences seem to cause activity in the left frontal lobe more than the right (NB decreased alpha waves = increased brain activity). EEG is used clinically to investigate brain wave abnormalities for example in epilepsy, brain injury and brain tumors. It cannot be used to diagnose brain death since patients with Persistent Vegetative State (PVS - a kind of coma) are alive but may have no brain waves.
There are companies that market perfumes with claims that they do relax you. The problem is complicated by the many things that can affect psychological state. But, there are effects that can be measured under certain circumstances.

SUMMARY OF THE INVENTION
The literature reviewed in description of the prior art section correlates the facts that person can recovered from unconsciousness only by inhaling the specific smell. The association of fragrance and emotion is not an invention of poets or perfume-makers. Our olfactory receptors are directly connected to the limbic system, the most ancient and primitive part of the brain, which is thought to be the seat of emotion. Smell sensations are relayed to the cortex, where 'cognitive' recognition occurs, only after the deepest parts of our brains have been stimulated. Thus, by the time we correctly name a particular scent as, for example, 'vanilla', the scent has already activated the limbic system, triggering more deep-seated emotional responses. Even this is not very surprising, as any strong odour will have a stimulating effect, which will cause a general increase in blood flow to the extremities inevitably including the penis.
Aromatherapy is a form of alternative medicine that uses volatile liquid plant materials, known as essential oils (EOs), and other aromatic compounds from plants for the purpose of affecting a person's mood or health. Aromatherapy is a generic term that refers to any of the various traditions that make use of essential oils sometimes in combination with other alternative medical practices and spiritual beliefs. Popular use of these products includes massaging products, medicine, or any topical application that incorporates the use of essential oils to their products. Aromatherapy has been defined as 'the art—and science—of using essential oil in treatments. Aromatherapy is a valuable means of maintaining optimum health, particularly when the disease of the body or mind is related stress. Certain herbs, such as valerian, kava (Kava Kava), chamomile, Kratom, Blue Lotus extracts, Sceletium tortuosum (kanna) and bacopa monniera are reputed to have anxiolytic properties. Pineapple sage, or salvia elegans, is used as

a treatment for anxiety in traditional Mexican medicine, and a preliminary study on mice has yielded some support for both anxiolytic and antidepressant properties.
Broome etal 1990, Kachoyeanos & Friedhoof 199, Strachan 1993, Taylor 1991 examined the ways in which massage and aromatherapy could be of benefit to hospitalized children, particularly those infected with Human Immunodeficiency Virus (HIV). Wright (1995) states that nurse should encourage self-healing by putting patient in the best condition for nature to act. They conclude that aromatherapy has the potential to achieve this through inducing relaxation and reducing the stressful aspects of hospitalization.
Prior Art:-
While certain medical uses for essential oils have been previously disclosed, to the inventor's best knowledge, none of those previously disclosed methods that have suggested, or proposed, the aroma in inhaler for periodic inhalation of vapors from naturally identical novel aroma composition consists of more then 50 compounds included Saussurea gossypiphora ,Johan Wart Neroli and Priyangu etc . Thus, the author would like to propose the use of this valuable novel aroma composition to treat many psychological disorders only by inhalation.
Further this composition may be used as sympathomimetic drugs after clinical trials without any cytotoxic effect on humans.The novel aroma composition has anti stress effect, which substantially prevents depression and anxiety by triggering the limbic system of the brain of human beings for duration of time following that inhalation. After the infection of human beings with certain pathogens, previous inhalation therapies have suggested using essential oil aid in the recovery from certain respiratory diseases.

However, none of these previous methods have suggested use of the blend of essential oil in inhaler as anti depression and prophylactic agents, which routinely and substantially PREVENT the depression and anxiety for duration of time following their inhalation as a primary method of preventing disease.
The main utility of the invention is to provide lead novel aroma Composition consists of more than many compounds isolated from many medicinal herbs. This invention provides the new inhalation drugs for the treatment of several psychosomatic and inflammatory diseases in which Tuaminoheptane plays an important role as sympathomimetic agent in humans.
DETAILED DESCRIPTION OF PREFERRED EMBODIMENTS
Fragrances, aromas, are commonly dispersed, into the atmosphere for a wide variety of reasons. To these ends, fragrances and aromas are used in retail spaces to improve and focus customer sales, in emotional therapy (aromatherapy) to soothe the psyche, in work places to invigorate the mind, and in medical therapy to soothe both the practitioner and the patient while improving healing rates in a stressful environment.
It is well established that olfactory system is impaired in several neurological diseases, such as Parkinson's, Alzheimer's, and Korsakoffs (see Gregson et al, 1981; Talamo et al, 1989; Herz and Engen, 1996; Doty, 2001; Zucco et al, 2001), and also in Down syndrome subjects and HIV-infected patients (see Lehrner et al, 1995; Zucco and Savoldelli, 1996; Hornung et al, 1998; Zucco and Ingegneri, 2004). However, only few studies are available on olfactory function in patients affected by various kinds of liver diseases, although it is well known that liver

dysfunction might lead to central nervous disorders. The available studies have already investigated the impact of acute (Henkin and Smith, 1971), chronic (Burch et al., 1978; Landis et al, 2004), and end stage liver disease (Bloomfeld et al, 1999). According to these authors, diverse aspects of olfactory function are altered to a variable degree by underlying liver disease. Furthermore, a recent study on chronic liver cirrhosis (Temmel et al, 2005) emphasized the possibility of hepatic encephalopathy (HE) to influence olfactory central tasks.
Ballard et.al. were reported the neurological effect of Melissa (lemon balm) essential oil was dispensed in metered does of 0.16 to 0.17 grams of lotion which improves in physical non-aggressive agitation (motor restlessness) verbal non-aggression (shouting, screaming) and physical aggressiveness. In addition to using Melissa oil, Chenoweth recommends that people who have dementia depending on their health status and behaviors, might benefit from other natural agents with calming properties, such as lavender, geranium, orange or mandarin.
Itai, et.al. conducted the clinical trial in 14 female patients with chronic renal failure, Hospitalized for hemodialysis at Hirosake Hospital, Japan. All 14 patients included in this study met the criteria for mild to severe depression. They conclude that lavender had a sedative effect on the central nervous system. It is reasonable, therefore, to expect that fragrance may have antidepressant and anxiolytic effects. Hiba oil has both antidepressant and anti anxiety effects in chronic hemodialysis patients, while lavender has anxiolytic effects in such patients, regardless of presence of physical complications.
Chu et. al. reviewed the literature and concluded that the use of specific scent or odour have Potential Clinical Benefits in Cardiovascular (angioprotectant), Pulmonary (expectorant, Renal and Electrolyte balance, Neuro-psyhiatric sedative, hymnotic,anxiolytic, anticonvulsant, effects on mood, effects on cognitive function analgesic. Endocrine, hypoglycemic effects, Rheumatologic;

Reproductive: emmenagogue, aphrodisiac, perineal repair, Immune modulation:
anti inflammatory, Antimicrobial: antibacterial, antifungal,
insecticide; Antioxidant, Hair growth stimulant.
B.F. Bradley et. al. 2006 reported the Anxiolytic effects of Lavandula angustifolia odour on the Mongolian gerbil elevated plus maze and concluded that exposure to specific odour may have an anxiolytic profile in gerbils similar to that of the anxiolytic diazepam. In addition, prolonged, 2-week lavender odour exposure increased exploratory behavior in females indicating a further decrease in anxiety.
Reinaldo N6brega de Almeida et. al. 2003 reported the Anxiolytic-like effects of rose oil inhalation on the elevated plus-maze test in rats and concluded that Exposure to rose oil produced an anxiolytic-like effect similar to DZP (anxiolytic reference drug).
Lehrner, J. et al. 2005 shown that vapors of essential oils such as neroli and lavender could help reduce anxiety levels. Inhalation of these essential oils may trigger the limbic system of the brain giving the resulting beneficial effects. However, .Bradley, B.F et. al. 2007 had suggested that further investigation of these oils was needed to provide evidence that they relieve anxiety.
It is evident from the above that need exists for development of new drug for mood elevating and anxiety ,stress and tension reducer through inhalation , which stimulates the olfactory bulb be mediated by GABA .

The novelty of the present invention is to provide the novel aroma composition consists of many compounds isolated from the medicinal plants first time in the history ,as serotonin reuptake inhibitor and a PDE4-inhibitor for mood elevating and anti- anxiety effect , anti stress effect and tension reducer through inhalation and which is effective at very low concentration and not have any cytotoxic as compared to other aromatic compound compassions already reported from the different plant.
OBJECTS OF THE INVENTION
1. The major object of the present invention is to provide the process for
isolation for novel aroma composition from medicinal plant.
2. Clinical study of novel aroma composition compounds as
sympathomimetic agent on humans after inhalation.
3. Still another object of the present invention is to provide a method for testing the novel aromatic principles present in plant matrix of by most advanced analytical instrument Dynamic Head Space with GC/MS/MS.
4. Yet another object of the invention is to provide usage of the novel aromatic principles compounds as an anti depressant in inhaler.
5. One most important object of the present invention relates to the pharmacological study of novel aromatic composition of on following parameters.
a. Alpha-wave content by EEC

b. Sedative effect of novel aroma composition after inhalation.
c. Effect on novel aroma composition on GABAergic system.
d. Inhibitory activity of pre inhalation of the novel aroma composition on
lipid per oxidation for anticonvulsive action.
e. Study the effect of novel aromatic composition on G-proteins in the
olfactory epithelium.
6. The yet another aspect of the present invention is, the comparative study of the novel aroma compositions with benzodiazepine to treat anxiety disorders, panic attacks and nervous tension, different types of phobias, depression, insomnia and others.
EXAMPLE 1
The present inventors investigated the various combination of naturally identical compounds isolated from medicinal and aromatic plants in order to develop an effective and safe anti-stress agent and, as a result, we have found expectedly that an exact composition of compounds present in our formulated aroma ,only exhibits the best combination for treatment of general psychological problems through inhalation.

EXAMPLE 2
The novel aroma composition according to the above, wherein the aroma component is only the combination of all or some of following constituents isolated from following plants.
• Basil is used in perfumery for its clear, sweet and mildly spicy aroma. In aromatherapy, it is used for sharpening concentration, for its uplifting effect on depression, and to relieve headaches and migraines. Basil oil has many chemotypes and some are known to be emmenagogues and should be avoided during pregnancy.
• Bergamot is one of the most popular oils in perfumery. It is an excellent insect repellent and may be helpful for both the urinary tract and for the digestive tract. It is useful for skin conditions linked to stress, such as cold sores and chicken pox, especially when combined with eucalyptus oil. Bergamot is a flavoring agent in Earl Grey tea. But cold-pressed Bergamot oil contains bergaptene, a strong photosensitizer when applied to the skin, so only distilled or "bergaptene-free' types can be topically used.
• Black pepper has a sharp and spicy aroma. Common uses include stimulating the circulation and for muscular aches and pains. Skin application is useful for bruises, since it stimulates the circulation.
• Citronella oil, obtained from a relative of lemongrass, is used as an insect repellant and in perfumery.
• Tea tree oil and many other essential oils have topical (external) antimicrobial (i.e. antibacterial, antifungal, antiviral, or antiparasitic) activity and are used as antiseptics and disinfectants.[15]
• Eucalyptus oil is often used in combination with Mint to provide relief for the airways in case of cold or flu.

• Sandalwood oil
• Thyme oil
• Clove oil is a topical analgesic, especially useful in dentistry. It is also used an antiseptic, antispasmodic, carminative, and antiemetic.
• Lavender oil is used as an antiseptic, to soothe minor cuts and burns, to calm and relax, and to soothe headaches and migraines.
• Yarrow oil is used to reduce joint inflammation and relieve cold and influenza symptoms.
• Jasmine, Rose, Sandalwood and Ylang-ylang oil are used as aphrodisiacs.
• Lemon oil is uplifting and anti-stress/anti-depressant. In a Japanese study, lemon essential oil in vapour form has been found to reduce stress in mice.
• Agar oil, distilled from Agarwood (Aquilaria malaccensis). Highly prized for its fragrance.
• Ajwain oil, distilled from the leaves of Bishop's weed (Carum copticum). Oil contains 35-65% thymol
• Angelica root oil, distilled from the Angelica archangelica.
• Anise oil, from the Pimpinella anisum, rich odor of licorice, used medicinally.
• Balsam oil, from the Myroxylon pereirae.
• Basil oil is used in making perfumes, as well as in aromatherapy
• Bay is used in perfumery; Aromatherapeutic for sprains, colds, flu, insomnia, rheumatism.
• Bergamot oil, used in aromatherapy and in perfumes.
• Black Pepper essential oil is distilled from the berries of Piper nigrum. The warm, soothing effect makes it ideal for treating muscle aches, pains and strains.
• Buchu oil, made from the buchu shrub. Considered toxic and no longer widely used. Formerly used medicinally.

• Birch is aromatheapeutic for gout, Rheumatism, Eczema, Ulcers.
• Camphor is used for cold, cough, fever, rheumatism, arthritis
• Cannabis flower essential oil, used as a flavoring in foods, primarily candy and beverages. Also used as a scent in perfumes, cosmetics, soaps, and candles.
• Caraway oil, used a flavoring in foods. Also used in mouthwashes, toothpastes, etc. as a flavoring agent.
• Carrot seed oil (essential oil), used in aromatherapy.
• Cedarwood oil, primarily used in perfumes and fragrances.[9]
• Chamomile oil, There are many varieties of chamomile but only two are used in aromatherapy- Roman and German. Both have similar healing properties but German chamomile contains a higher level of azulin (an antiinflammatory agent).
• Calamus Root, used medicinally
• Cistus species
• Citronella oil, from a plant related to lemon grass is used as an insect repellent, as well as medicinally.
• Clary Sage
• Clove leaf oil, used as a topical anesthetic to relieve dental pain.
• Coffee, used to flavor food.
• Coriander
• Costmary oil (bible leaf oil), from the Tanacetum balsamita
• Costus Root, used medicinally
• Cypress
• Cypriol
• Davana oil,
• Dill oil, chemically almost identical to caraway seed oil. High carvone content.
• Elecampane, used medicinally.

• Eucalyptus oil, historically used as a germicide. Commonly used in cough medicine, among other medicinal uses.[13]
• Fennel seed oil, used medicinally, particularly for treating colic in infants.
• Fenugreek oil, used medicinally and for cosmetics from ancient times.
• Fir
• Frankincense oil, used for aromatherapy and in perfumes.
• Galangal, used medicinally and to flavor food.
• Galbanum
• Geranium oil, used medicinally, particularly in aromatherapy, used for hormonal imbalance, for this reason geranium is often considered to be "female" oil.
• Ginger oil, used medicinally in many cultures.
• Goldenrod
• Grapefruit oil, extracted from the peel of the fruit. Used in aromatherapy. Contains 90% limonene.[14]
• Henna oil, used medicinally.[15]
• Helichrysum
• Horseradish oil
• Hyssop
• Idaho Tansy
• Jasmine oil, used for its flowery fragrance.
• Juniper berry oil, used as a flavor. Also used medicinally, including traditional medicine
• Laurus nobilis
• Lavender oil, used primarily as a fragrance. Also used medicinally.[16]
• Ledum

• Lemon oil, similar in fragrance to the fruit. Unlike other essential oils, lemon oil is usually cold pressed. Used medicinally, as an antiseptic, and in cosmetics.[17]
• Lemongrass. Lemongrass is a highy fragrant grass from India. In India, it is used to help treat fevers and infections. The oil is very useful for insect repellent.
• Lime, anti septic, anti viral, astringent, aperitif, bactericidal, disinfectant, febrifuge, haemostatic, restorative and tonic.[18]
• Litsea cubeba oil, lemon-like scent, often used in perfumes and aromatherapy.
• Mandarin
• Marjoram
• Melaleuca See Tea tree oil
• Melissa oil (Lemon balm), sweet smelling oil used primarily medicinally, particularly in aromatherapy.
• Mentha arvensis oil/Mint oil, used in flavoring toothpastes, mouthwashes and pharmaceuticals, as well as in aromatherapy and other medicinal applications.[19]
• Mountain Savory
• Mugwort oil, used in ancient times for medicinal and magical purposes. Currently considered to be a neurotoxin.[20]
• Myrrh oil, warm, slightly musty smell. Used medicinally.
• Myrtle
• Neroli is produced from the blossom of the bitter orange tree.
• Nutmeg
• Orange oil, like lemon oil, cold pressed rather than distilled. Consists of 90% d-Limonene. Used as a fragrance, in cleaning products and in flavoring foods.[21]

• Oregano oil, contains thymol and carvacrol, making it a useful fungicide. Also used to treat digestive problems.[22]
• Orris oil is extracted from the roots of the Florentine iris (Iris florentina) and used as a flavouring agent, in perfume, and medicinally.[23]
• Palo Santo
• Parsley oil, used in soaps, detergents, colognes, cosmetics and perfumes, especially men's fragrances.[24]
• Patchouli oil, very common ingredient in perfumes.
• Perilla essential oil, extracted from the leaves of the perilla plant. Contains about 50-60% perillaldehyde.
• Pennyroyal oil, highly toxic. It is abortifacient and can even in small quantities cause acute liver and lung damage.[25]
• Peppermint oil, used in a wide variety of medicinal applications.
• Petitgrain
• Pine oil, used as a disinfectant, and in aromatherapy.
• Ravensara
• Red Cedar
• Roman Chamomile
• Rose oil, distilled from rose petals, Used primarily as a fragrance.
• Rosehip oil, distilled from the seeds of the Rosa rubiginosa or Rosa mosqueta. Used medicinally.
• Rosemary oil, distilled from the flowers of Rosmarinus officinalis. Used in aromatherapy, topically to sooth muscles, and medicinal for its antibacterial and antifungal properties.[26]
• Rosewood oil, used primarily for skin care applications. Also used medicinally.
• Sage oil, used medicinally.

• Sandalwood oil, used primarily as a fragrance, for its pleasant, woody fragrance.[27]
• Sassafras oil, from sassafras root bark. Used in aromatherapy, soap-making, perfumes, and the like. Formerly used as a spice, and as the primary flavoring of root beer, inter alia.
• Savory oil, from Satureja species. Used in aromatherapy, cosmetic and soap-making applications.
• Schisandra oil, from Schisandra chinensis, used medicinally.
• Spearmint oil, often used in flavoring mouthwash and chewing gum, among other applications.
• Spikenard, used medicinally.
• Spruce
• Star anise oil,
• Tangerine
• Tarragon oil, distilled from Artemisia dracunculus, used medicinally.
• Thyme oil, used medicinally.
• Valerian, used medicinally
• Vetiver oil (khus oil) a thick, amber oil, primarily from India. Used as a fixative in perfumery, and in aromatherapy
• Western red cedar
• Wintergreen
• Yarrow oil is used medicinally, to relieve joint pain
• Ylang-ylang
• Zedoary, used medicinally and to flavor food

EXAMPLE 3
More particularly, the present inventors conducted screening of substances having anti-stress activity using, as an index, the enhancing effect on GABA response of an oocyte of Xenopus in which GABA receptor is expressed. As a result, the present inventors have found that novel aroma composition has activity to enhance GABA response of GABA receptor. Further, the present inventors conducted in vivo pharmacological study using, as an index, the activity to extend duration of the sleeping time novel aroma composition remarkably extends the duration of the sleeping time. As described above, since the central GABA nervous system plays an important role in relaxing stress, aroma components of coffee or teas have an effect to alleviate stress via the activation of central GABA receptor.
EXAMPLE 4
In another embodiment of present invention is said to be The general psychological problems through inhalation and anti-stress agent according to the above (1), wherein the novel aroma composition mixed in equal proportions present in the flower of plant which is approximately 1 milliliter per 120 milliliters of carrier.

EXAMPLE 5
In another embodiment of present invention is said to be trial base formulation in which eight participants' was selected for study not receiving treatment for psychological disorders. Intervention: Participants were randomly allocated to use novel aroma composition in their bath for 14 days. Results: The psychologically positive mood changes were found after the bathing regimen for energetic arousal, tense arousal, hedonic tone and anger-frustration; negative responses about the future were also selectively reduced in intervention group
EXAMPLE 6 ii) Test Method
Smelling bottles containing filter paper to which a novel aroma composition was adhered or non-stimulating odorless filter (blank) were prepared. Electrodes to contingent negative variation (CNV), and alpha and beta event-related desynchronization (ERD) recording were placed on predetermined sites of the volunteers. While recording electroencephalograms, vertical oculogyration, and respirations, panel members were made to sniff at the smelling bottle,and responses to a sound stimulus were recorded. A percentage of the sum of CNV of from 400 to 1000 msec from the sound stimulation when the novel aroma composition was given a sniff to that of the blank was obtained. The Effects were assessed on reaction time (RT),

EXAMPLE 7 iii) Test Results
The subjects showed values higher than 100%, indicating that novel aroma composition gives a mood elevating effect and reduces the level of stress. It can be seen from the results that novel aroma composition only through inhalation give humans better psychological status similar to those produced by other psychological drugs.
EXAMPLE -8
The resulting aroma composition had a novel and particular keynote with a floral scent. A tone of novel aroma composition having was prepared by the combination of following naturally identical compounds.

(Table Removed)
EXAMPLE 9
The resulting novel aroma composition was also evaluated for its Dementia, Isomania properties by using it as scent, in bathing , in room dispensing and by direct inhaling .As a result, 24 out of 30 volunteers answered that they felt the effect of inhaling of novel aroma composition on elevating their mood , reduce in their stress condition and preferred the aroma of novel aroma composition as best inhaling drug for improving the mental capacity, concentration improving, beneficial for memory loss, for bring back the normal sleep ,combats mental fatigue.

In another embodiment of present invention is said to be provide the novel aroma preparation of the naturally identical chemicals with fresh, natural, diffusible and highly specific note never used earlier for the said purposes.
In another embodiment of present invention is said to be the method which could be used for the preparation such type of therapeutic composition which is not available commonly and lead to its extinction and have great therapeutic properties.
In another embodiment of present invention is said to be the novel aroma composition of the present invention has outstanding characteristics to treat several mental disorders, including loss of consciousness, mania, and emotional agitation and giving humans a Sympathomimetic therapeutic effect.
In another embodiment of present invention is said to be the inhalation, bathing, dispensing of novel aroma composition for specific duration on humans which have various effects on brain.
In another embodiment of present invention is said to be the stimulation of the limbic system of brain and use of novel aroma composition to treat the very severe cases of brain disorder, especially when the person is losing consciousness or suffering from severe delirium.
In another embodiment of present invention is said to be the simultaneous use of novel aroma composition for therapeutic purpose as well as use in broad range of applications such as perfuming, cosmetics, sanitary goods etc.

Although the descriptions in the above paragraphs contain much specificity, these should not be construed as limiting the scope of the invention, but merely as illustrating the presently preferred method of prevention and treatment of CNS disorders. The scope of the invention should be determined by the appended claims and their legal equivalents, rather than solely by the examples given. While the invention has been described in detail and with reference to specific examples thereof, it will be apparent to one skilled in the art that various changes and modifications can be made therein without departing from the spirit and scope thereof.