Description:FIELD OF INVENTION
The present invention relates generally to nutraceutical and herbal ingredients and more specifically to a blend of such ingredients including Mangosteen Extract, Safed Musli Extract, Siberian ginseng Elderberry Extract, Bilberry Extract, Ashwagandha Extract, Ginkgo Biloba Extract, Manjistha Extract, Sigru, Shatavari Extract, Punarnava Extract and Gokshura Extract.
BACKGROUND OF THE INVENTION
Nutraceutical is defined as a food or part of it that provides the body with medical or health benefits, including the prevention and treatment of a disease. It is seen as a more natural way to accomplish therapeutic results with minimal side effects, and this view has propelled the discovery and production of nutraceutical to become a multibillion dollar enterprise. Nutraceuticals are derived from herbal products, minerals, vitamins and dietary substances which are consumed for their physiological benefits or to boost immunity against diseases.
Nutraceuticals are consumed with generally three ways: functional food, beverages and dietary supplements. While nutraceuticals such as breakfast cereals, and fortified flour are consumed as functional food, functional beverages include commodities like sports drinks, fortified juices, and glucose. Dietary supplements can be commodities such as macronutrients, herbal and non-herbal extracts.
Unfortunately, there are various fortified products available in the market which contain some vitamins and minerals resulting in Headche, Dizziness, Elevated blood pressure, Indigestion etc.
A more efficient and less disservice herbal product for health is desired.
SUMMARY OF THE INVENTION
An extract combination is formulated to improve a person's wellbeing, with possible implications to enhance immunity and further lowering the risks of cardiovascular and/or Alzheimer's diseases and/or lowering blood sugar using natural ingredients. A mixture formulation of the present invention may be used as a food or a drink or a supplement or a drug in a tablet or capsule form or a cosmetic or a hygienic product. Numerous ratios may be formulated for aroma, color, flavor, flow (viscosity), taste and uniformity. The mixture may be diluted with water, beverages and/or milk.
Therefore such as herein described there is provided a nutraceutical mixture formulation, the formulation consisting essentially of a dried mixture of ingredients including Mangosteen Extract, Safed Musli Extract, Siberian ginseng, Elderberry Extract, Bilberry Extract, Ashwagandha Extract, Ginkgo Biloba Extract, Manjistha Extract, Sigru, Shatavari Extract, Punarnava Extract and Gokshura Extract.
In a preferred embodiment, there is provided a nutraceutical composition consisting of extracts of such herbal ingredients with a predetermined quantity in total 350 mg such as Mangosteen Extract(56mg), Safed Musli Extract(26mg), Siberian ginseng(18mg),Elderberry Extract(27mg), Bilberry Extract(31mg), Ashwagandha Extract(41mg), Ginkgo Biloba Extract(24mg), Manjistha Extract(29mg), Sigru(24mg), Shatavari Extract(21mg), Punarnava Extract(27mg) and Gokshura Extract(26mg) with pharmaceutically acceptable salts, preservative and flavoring agents to prepare different drug delivery system.
The present invention also provides a method of manufacturing such nutraceuticals product by way of dispensing wherein specific amounts of raw materials from bulk container are weighed and transferred to smaller unit which is required for manufacturing of a specific batch; sifting wherein all the dispensed material are shifted for so that undesirable undersized portions of the raw materials are separated; blending wherein the materials are added to cone blender mixer; capsule filling wherein the hard pieces of capsule can be filled with material by using different filling machine; capsule polishing and finally sent for inspection.
OBJECT OF INVENTION
A primary object of the present invention is to provide a nutraceutical composition that contributes to general human wellness and good health through a novel and mixture of Mangosteen Extract, Safed Musli Extract,Siberian ginseng Elderberry Extract, Bilberry Extract, Ashwagandha Extract, Ginkgo Biloba Extract, Manjistha Extract, Sigru, Shatavari Extract, Punarnava Extract and Gokshura Extract with a predetermined ratio so that chances of side effect can turn into minimal and effectiveness raises upto maximum. The effectiveness of this mixture is heightened through the addition of flavoring and preservatives in varying amounts as required.
Another object of the present invention is to provide a nutraceutical formulation that offers the holistic benefits of the ingredients including Mangosteen Extract, Safed Musli Extract,Siberian ginseng Elderberry Extract, Bilberry Extract, Ashwagandha Extract, Ginkgo Biloba Extract, Manjistha Extract, Sigru, Shatavari Extract, Punarnava Extract and Gokshura Extract and is an efficacious source of natural highly absorbing vitamin, minerals and compounds (not synthetic compounds) with antimicrobial, anti-inflammatory, antioxidative, antibacterial and nutritional properties.
The foregoing and other objects, advantages and characterizing features will become apparent from the following description of certain illustrative embodiments of the invention.
While the methods and processes of the present invention have proven to be particularly useful in the area of nutritional health supplements, those skilled in the art can appreciate that the methods and processes can be used in a variety of different applications and in a variety of different areas of manufacture to satisfy a wide-ranging variety of food / dietary supplement, pharmaceutical and medicinal needs.
The above-described features and advantages of the present invention, as well as additional features and advantages, will be set forth or will become more fully apparent in the description that follows and in the appended claims. The novel features which are considered characteristic of this invention are set forth in the attached claims. Furthermore, the features and advantages of the invention may be learned by the practice of the invention, or will be obvious to one skilled in the art from the description, as set forth hereinafter.
Further areas of applicability of the present invention will become apparent from the detailed description provided hereinafter. It should be understood that the detailed description and specific examples, while indicating the preferred embodiment of the invention, are intended for purposes of illustration only and are not intended to limit the scope of the invention.
DETAILED DESCRIPTION OF THE INVENTION
The following description of the preferred embodiment(s) is merely exemplary in nature and is in no way intended to limit the invention, its application, or uses.
The present invention relates to nutraceutical composition more specifically capsules derived from the ingredients such as Mangosteen Extract, Safed Musli Extract, Siberian ginseng Elderberry Extract, Bilberry Extract, Ashwagandha Extract, Ginkgo Biloba Extract, Manjistha Extract, Sigru, Shatavari Extract, Punarnava Extract and Gokshura Extract. The invention also relates to processes for manufacturing the nutraceutical formulations described herein in an economical manner.
Unless defined otherwise, all technical and scientific terms used herein have the same meanings as commonly understood by one of ordinary skill in the art to which this invention belongs. Preferred methods, formulations, and materials of the present invention are described herein, although any methods and materials similar or equivalent to those described herein can be used in the practice or testing of the present invention. All references cited herein are incorporated by reference in their entirety.

Brief description of the ingredients and their uses

MANGOSTEEN
Mangosteen is also called the "QUEEN OF FRUITS" & Food of Gods and is a rich source of antioxidants and vitamin C. It has been found that its extract can neutralize up to 20–30 times more free radicals than any other natural sources. Mangosteen is good in vitamin C which is a powerful water soluble ANTIOXIDANTS. Mangosteen helps to strengthen the immunity system.
It promotes joint & cartilage function supports a strong respiratory system and help in maintaining good health. The active therapeutic compound found in Mangosteen is called “XANTHONES”. Xanthones are a family of phytonutrients loaded with potent of health benefits and antioxidants properties. Xanthones in Mangosteen have the ability to eradicate and destroy cancer cells. The mangosteen fruit is said to contains at least 43 known Xanthones, majority of which are found in the fruit wall or pericarp of the fruit.
Xanthones work to reduce oxidative stress caused by free radicals. By damaging the free radicals, these antioxidants protect the body from various diseases, ranging from common cold and Flu, Cancer risk and Heart disorders.
There are over 200 XANTHONES found in nature. Mostly in wood, lichens and moss, which are mostly unpalatable and inedible. But 43 of them are in the Mangosteen, 3 in pulp and 40 in the pericarp. The highest recorded amount of XANTHONES present in Mangosteen than anything else. Xanthones represents the very latest that nutritional science has to offer. Much more than a great Antioxidants, Xanthones are a class of multi-functional phytonutrients poised to raise the bar in the nutritional arena! At our company, we have not only launched a category creator, we are the next generation of supplementation.
"Mangosteen provides powerful support for every organ system in the human body. This fact is being confirmed on a daily basis by clinical experience... I am convinced that Mangosteen will, without a doubt, be the most successful food supplement ever." - J. Frederic Temple man, M.D., a primary care physician for more than 20 years and board certified in both the United States and Canada.
"Mangosteen is able to reverse most of the ailments of modern man." - Kenneth J. Finsand, M.D., a practicing chiropractic physician for nearly 30 years who specialized in functional medicine throughout his medical career.
"Mangosteen provides huge health benefits for every organ in our bodies."- Sam Walters, N.M.D., a family practitioner trained as a specialist in both traditional and natural medicine, with more than 30 years of comprehensive practical experience in the medical profession, and formulated nutritional products for companies and institutions including the NASA Space Center for the astronauts.
Mangosteen contains more than 40 biologically-active, natural chemical compounds called Xanthones. While all these Xanthones have similar molecular structures, each one has its own unique chemical formulation that permits it to perform a specific function. Alpha-mangostin, for example, is a very potent antioxidant. Gamma-mangostin is a powerful anti-inflammatory. Garcinone E is a strong anti-tumor agent. These and the other Xanthones found in the Mangosteen provide a virtual medicine chest of natural healing compounds that address a wide variety of health issues.
Centuries of Mangosteen use has helped Southeast Asians maintain or regain their health and cure their diseases. Traditional Asian healers use the fruit to stop infection, treat inflammation, and increase one's energy, among others.
Modern scientists and a growing number of health practitioners now agree on the medical benefits of Mangosteen. They have found that the fruit is helpful in preventing and possibly even stopping a wide range of diseases such as diabetes, heart disease, Alzheimer's disease, cancer and other chronic diseases.
Those who have taken the time to do their own research on the validity of each health benefit of Mangosteen will find that there is real and solid science behind the "Queen of Fruits".
Our immune system tries to keep trillions of cells in our bodies protected from disease-causing toxins, free radicals, viruses, bacteria, fungi and other harmful agents.
At times, though, our immune system gets overwhelmed. Our bodies get sick, often because of free radical damage.
A free radical is an unstable atom with an unpaired electron. When a free radical comes in contact with a stable atom, it steals the electron it needs from the stable atom. This leaves the once stable atom irreparably damaged and prone to succumb to disease.Antioxidants counteract free radicals. They have an extra electron that they can share with free radicals. Because of this ability, they are able to prevent free radicals from attacking healthy atoms or cells.
Mangosteen contains powerful antioxidants and immune system boosters called Xanthones, natural chemical compounds which were proven to possess a variety of potent medicinal properties.
Xanthones occupy a special place in the Mangosteen's arsenal of healing compounds. They have been shown to have more potent antioxidant activity than vitamin E, one of nature's most powerful known antioxidants.
A laboratory test known as ORAC (Oxygen Radical Absorbance Capacity), for example, showed that an ounce of Mangosteen extract provides 20 to 30 times more capacity to absorb free radicals than an ounce of most fruits and vegetables.
Mangosteen also contains other potent natural compounds like catechism, polysaccharides, quinines, stilbenes and polyphenols.Catechism were discovered to be five times more potent as antioxidants than vitamin C.
Polysaccharides are highly potent anti-cancer and anti-bacterial plant compounds. They help block a mutated cells ability to stick to healthy cells to help stop the spread of cancer, and are especially effective against intracellular bacteria.
Quinones are known for their anti-bacterial properties and also are strong antioxidants. Stilbenes in plants defend these plants against fungi. Interestingly, stilbenes also maintain their anti-fungal properties even when ingested. They also are strong antioxidants.
Polyphenols were found to be far more potent as antioxidants than vitamin E, considered one of the most powerful known antioxidants.
• Anti-aging - helps prevent aging
• Anti-allergenic - helps prevent allergic reactions
• Anti-arthritic – helps prevent arthritis
• Anti-atherosclerotic - helps prevent the hardening of the arteries
• Antibiotic - prevents or modulates bacterial infections
• Anti-calculi tic - helps prevent kidney stones
• Anti-cataract - helps prevent cataracts
• Antidepressant – helps with depression
• Anti-diarrheal – helps with diarrhea
• Anti-fatigue - helps relieve fatigue
• Antifungal - prevents or modulates fungal infections
• Anti-glaucoma - helps prevent glaucoma
• Anti-Inflammatory – helps with inflammation
• Anti-lipid emic - helps lower blood fat
• Anti-neuralgic - helps in nerve pain
• Anti-obesity - helps in weight loss
• Anti-osteoporosis - helps prevent the loss of bone mass
• Antioxidant-rich – rich in antioxidants
• Anti-Oxo lytic - anti-anxiety
• Anti-Parkinson - helps with Parkinson's disease
• Anti-periodontics - helps prevent gum disease
• Antipyretic - helps lower fever
• Anti-tumor and cancer-preventive
• Anti-vertigo - helps prevent dizziness
• Antiviral - prevents or modulates viral infections
• Cardio-protective - helps in the protection of the heart
• Hypoglycemic - helps stabilize blood sugar
• Hypotensive - helps lower blood pressure
• Immunostimulant – helps the immune system fight infection

SIBERIAN GINSENG EXTRACT
Siberian Ginseng has a history of traditional use dating back more than 2,000 years. It was traditionally consumed to maintain overall good health as opposed to treating ill health, and was especially important to the elderly to boost the quality of life. In the past it was used in Traditional Chinese Medicine, where it was mixed into wine and combined with other herbs to be used as a tonic for fatigue, arthritis and pain in the lower back.
In his “Great Catalogue of Medicinal Herbs”, Li Shih Chen called Siberian Ginseng a superior herb, “Its action is to invigorate physical energy, regulate vigor, strengthen the skeleton and tendons, and increase one's ambition”. As a motivational herb, Siberian Ginseng is hard to beat – there isn’t much else that can deliver so much wonderful, raw energy.
Traditional Chinese Medicine specializes in being able to formulate whichever energy patterns are necessary for patients with herbs. Siberian Ginseng has been added to many formulas, increasing the effect of energy to every area of the body that needed it.
Rumor has it that Siberian Ginseng was the first ever herb to have the term “Adaptogen” applied to it. Adaptogens are a unique group of herbal ingredients which help your body adjust to stressful circumstances, ranging from extreme heat or cold to infections or trauma.
Siberian Ginseng aids in the recovery from strenuous exercise and extreme mental exertion. Its adaptogenic qualities make it a must have herb for those engaged in highly stressful jobs or high energy activities. It is also extremely useful to those working in abnormally high or low temperature environments.
Another important action of an adaptogen is “immunomodulation” – a process by which an immune response is altered to the desired level.
This is partly achieved by recharging exhausted adrenal glands - when these glands become over-taxed leading to different systems in the body to break down.
Siberian Ginseng consists of a group of glycosides known as eleutherosides. The evidence is mounting that Siberian Ginseng enhances and supports immune system response, making it a possible natural alternative in the long term management of various diseases of the immune system. German research has shown that it increases lymphocytes – important components of the immune system which act as the body’s primary defense against viral infections. They found that Siberian Ginseng significantly increases the activity and number of CD4 cells, a subset of T-lymphocyte cells, whose proper activity is crucial to the ability of the immune system to function normally.
Classed as a tonic herb and a mild stimulant, Siberian Ginseng has the ability to increase your work capacity after a single dose, increasing both immediate and long term energy.Besides protecting the body from stress, Siberian Ginseng also increases oxygenation of the cells, thereby increasing endurance, alertness and even visual acuity. This increased oxygenation leads to better circulation – especially to the brain – helping to restore memory, concentration and mental clarity.
A favorite supplement for professional runners, Siberian Ginseng delivers a powerful energy boost. It is so popular that it’s hard to find any runners who do not take it before a race – simply because they cannot outrun the other competitors who do use it. This adaptable herb is beneficial to both men and women in the realm of sexual health. In women it supports healthy menstruation and uterine tone. It is often prescribed by herbalists to combat infertility related depression and fatigue.
This potent root is an “adaptogen”, which means that when it is ingested, it helps the body to increase its resistance to stress. Guess what that means? If you take Siberian ginseng, your stress resistance can increase too.
Siberian ginseng has been known for aiding your immune system, helping your mental performance and mental health and increasing your energy, vitality and longevity. Siberian ginseng can also miraculously lower your blood sugar, which is one of the first steps to weight loss and preventing or recovering from diabetes.
Siberian ginseng has countless benefits for your physical and mental health, as well as your overall well-being. This is totally the time to indulge and take advantage of a large array of natural supplements When combined, many of these nutritional powerhouses, like Siberian ginseng work together and bring your body even more medicinal benefits.

SAFED MUSLI EXTRACT
The rare Indian herb Chlorophytum borivilianum (Liliaceae) is a famous magical folk cure with a long history and medical value. In Hindi, it’s known as ‘Safed musli,’ which means “white tubers.” It’s also known as “White gold” or “Divya aushad.” C. borivilianum is a widespread species used in Ayurvedic, Unani, Homeopathic, and Allopathic medicine, where the plant’s root plays a key role. Safed musli has traditionally been used to treat various male sexual issues and is considered a general health tonic. Due to its well-known aphrodisiac and immunomodulatory qualities, C. borivilianum is presently the most economically utilized species. It has only been used as a source of medication in India, and its newfound prominence as a herbal alternative to ‘Viagra’ has increased its popularity even in western countries.
In the United States and England, tubers are being used to make chips/flakes as a nutritious meal.2 In recent years, the demand for this plant has skyrocketed in both the Indian and international medicinal markets, and it is a crucial ingredient in over a hundred herbal drug compositions.3 The genus Chlorophytum is thought to have originated in tropical and subtropical Africa and was transported to India from South Africa. Saponins, flavonoids, alkaloids, steroids, triterpenoids, phenolic acids, Gallo-tannins, vitamins, potassium, magnesium, calcium, rare elements such as zinc, copper, phosphorous, resins, and a high quantity of simple sugars are all found in C. borivilianum.4 C. borivilianum roots contain glucose, protein, fibre, and saponin, alkaloids, saponins, polysaccharide, and protein.5 Saponins are found in the tubers, which have aphrodisiac, anti-ageing, adaptogenic, health-restorative, and health-promoting qualities.
Safed Musli are known to boost energy levels, relieve pre-natal and post-natal problems and act as a remedy for arthritis. Its purported use as an aphrodisiac agent may be a more recent discovery. Some online sources claim that the active components in the extract may include 25 different alkaloids, vitamins and minerals. These substances may be the underlying reason why it has been linked to increase sex drive and stamina. The mechanism may act by elevating male testosterone levels, which has been shown to influence virility and sex drive in men. We find in the male sexual enhancement category, the more promising supplements are those that contain a potent blend of proven ingredients, rather than just relying on a single ingredient. People may wish to consider some of the following substances: Tribulus Terrestris, Epimedium, Yohimbe Extract, MuiraPuama, Panax Ginseng, Catuaba Bark Extract and Damiana.

Nutritional Value of Safed Musli:

Nutritional Components Value (%)

Alkaloids
15-25
Total sugar 66.3

Total proteins 25.4

Glycosides 1.9-3.5

Carbohydrates 35-45

Crude fibre 25-35

Safed Musli can be used for multi purposely. It is used in Ayurveda, Unani, and homoeopathy, among other traditional medical systems. It has been used for a long time to treat arthritis, diabetes, cancer, increase vitality, improve sexual function, and various other ailments. It is also turning up in bodybuilding supplements these days.It is used in therapy as it has many medicinal properties like Aphrodisiac activity, Immunomodulatory activity,Antimicrobial activity, Antimutagenic activity, Adaptogenic activity, Antioxidant activity, Larvicidal activity, Blood glucose lowering activity, Antiulcer activity , Anthelmintic activity , Antistress activity etc.
By raising libido, safed musli may assist in improvement of sexual performance. It also aids in the increase of testosterone levels. According to a study, safed musli can also prevent premature ejaculation and boost sperm count. As a result, safed musli is utilized as an aphrodisiac and revitalizer.Safed musli has spermatogenic properties, which helps improve sperm quality and count. It also raises testosterone levels, which improves blood flow to the genitals and allows for longer erections. Thus, it is effective in male infertility and other sexual disorders like erectile dysfunction.
Safed musli is a great food to consume for people who are malnourished, emaciated, or underweight and need to gain lean muscle mass due to the presence of beneficial nutrients. Safed musli, as a dietary supplement, may aid muscular growth by increasing growth hormone level in exercise-trained adults.
Safed musli has a strong hypoglycaemic effect, which is essential for controlling blood sugar levels in the body. It also contains antioxidants, which protect the pancreas from damage. This aids in the improvement of insulin levels.
Safed musli saponins have anti-inflammatory and anti-arthritic properties. Inflammatory mediators such as histamine and prostaglandins, which cause pain and inflammation in arthritic patients, are inhibited.
Both the root powder and the safed musli pak are widely used in breastfeeding mothers to increase milk secretion from the mammary glands and are regarded as potent galactagogues.
Safed musli has a significant impact on the body’s overall stamina and energy levels. The powerful components and other herbs utilized in this composition help alleviate weakness and weariness while boosting the body’s vitality. It also helps to improve the function of the adrenal glands, which helps to lower stress levels and boost immunity.
Safed musli is widely used for eliminating microbes from the intestines that cause diarrhoea and other intestinal infections due to its excellent antibacterial and anti-diarrhoea qualities.
It is used to increase immunity and vigour in diarrhoea and dysentery patients. The powder of the root significantly reduces the frequency of passing stools while eliminating toxins from the body.
Because of its antistress and adaptogenic properties, safed musli may aid in stress management. It also possesses antioxidant properties, which help to reduce free radicals in the body and lessen the risk of oxidative stress-related illnesses.
Certain chemicals in safed musli, such as steroidal glycoside, have anti-cancer properties. If administered early in cancer development, it may also aid in cell apoptosis (cell death) and reduce tumour size and weight.

ELDERBERRY EXTRACT
Elderberry fruit contains high levels of flavonoids, which means it might have anti-inflammatory and antioxidant properties. These help to protect healthy cells from harmful free radicals that play a role in skin problems.
Used for its antioxidant activity to lower cholesterol, improve vision, boost the immune system, improve heart health and for coughs, colds, flu, bacterial and viral infections and tonsillitis. Elderberries have been a folk remedy for centuries in North America, Europe, Western Asia, and North Africa, hence the medicinal benefits of elderberries are being investigated and rediscovered. Bioflavonoids and other proteins in the extract destroy the ability of cold and flu viruses to infect a cell. People with the flu who took elderberry extract reported less severe symptoms and felt better much faster than those who did not.
Elderberries contain organic pigments, tannin, amino acids, carotenoids, flavonoids, sugar, rutin, viburnic acid, vitamin A and B and a large amount of vitamin C. They are also mildly laxative, a diuretic, and diaphoretic. Flavonoids, including quercetin, are believed to account for the therapeutic actions of the elderberry flowers and berries. According to test tube studies these flavonoids include anthocyanin’s that are powerful antioxidants and protect cells against damage.
Elderberries were listed in the CRC Handbook of Medicinal Herbs as early as 1985, and are listed in the 2000 Mosby's Nursing Drug reference for colds, flu, yeast infections, nasal and chest congestion, and hay fever. In Israel, Hadassah’s Oncology Lab has determined that elderberry stimulates the body's immune system and they are treating cancer and AIDS patients with it.
Elderberries contain high levels of vitamin A, which helps soothe the skin, help ease the appearance of age spots, and prevent or lessen wrinkles.
People have used elderberries for their potential health-boosting properties for many years, most notably to fight colds and the flu.
Elderberries contain high levels of fibre. Consuming elderberries as part of a healthful diet may lead to some health benefits, including protection from cardiovascular disease and colorectal cancer.

BILBERRY EXTRACT
Bilberry is a perennial shrub (∼ 35–60 cm in height) and belongs to the Ericaceae family, which grows in coniferous forests, moors and meadows of northern Europe and America, but it is also present in Asia. It is also known as European blueberry, huckleberry or whortleberry. It blooms from April through June, producing spheroidal blue/black colored fruits (∼5-9 mm in diameter) with many seeds that ripe from July through September. Its name is due to the intense color of the fruits and derives from the Danish word “bollebar” (dark berry). Bilberry is commonly known as a “super food”, due to its richness in health promoting compounds with several biological properties. Particularly, represents a rich source of anthocyanins, compounds that in the last years have gained research attention due to the numerous functions and applications.
Bilberry is the fruit of Vaccinium myrtillus. It originates in northern and central Europe. It is administered as a tea, historically for the amelioration of diarrhea and for mouth and throat inflammations. During World War II, British Royal Air Force pilots ate bilberry preserves to improve their vision on night sorties. Following the war, investigation confirmed that the extracts could improve visual acuity and accommodation between light and dark. The antidiarrheal properties are attributed to tannins that develop upon drying, the antiinflammatory action to a decrease in vascular permeability attributed to anthocyanoside cross-linking of collagen, and the visual effects are associated with the anthocyanidins.
Bilberry, (Vaccinium myrtillus), also called whortleberry, low-growing deciduous shrub belonging to the heath family (Ericaceae). It is found in woods and on heaths, chiefly in hilly districts of Great Britain, northern Europe, and Asia. The fruits are a principal food of the grouse and are used for tarts and preserves.
The stiff stems, 15 to 60 cm (6 to 24 inches) high, bear small egg-shaped leaves with serrated margins and small, globose, rosy flowers tinged with green. Bilberry is partly self-sterile but has been hybridized with the lingonberry (V. vitis-idaeus). The dark blue berries, ripening in July and August, have a waxy bloom and are about 1 cm (0.4 inch) in diameter. The berries are borne singly, in contrast to those of the much more productive cultivated blueberries (Vaccinium species) of the United States, which are borne in short clusters.

ASHWAGANDHA EXTRACT
Ashwagandha (Withania somnifera, fam. Solanaceae) is commonly known as “Indian Winter cherry” or “Indian Ginseng”. It is one of the most important herb of Ayurveda (the traditional system of medicine in India) used for millennia as a Rasayana for its wide ranging health benefits. Rasayana is described as an herbal or metallic preparation that promotes a youthful state of physical and mental health and expands happiness. These types of remedies are given to small children as tonics, and are also taken by the middle-aged and elderly to increase longevity. Among the ayurvedic Rasayana herbs, Ashwagandha holds the most prominent place. It is known as “Sattvic Kapha Rasayana” Herb (Changhadi, 1938). Most of the Rasayana herbs are adaptogen / anti-stress agents.
Ashwagandha is commonly available as a churna, a fine sieved powder that can be mixed with water, ghee (clarified butter) or honey. It enhances the function of the brain and nervous system and improves the memory. It improves the function of the reproductive system promoting a healthy sexual and reproductive balance. Being a powerful adaptogen, it enhances the body's resilience to stress. Ashwagandha improves the body's defense against disease by improving the cell-mediated immunity. It also possesses potent antioxidant properties that help protect against cellular damage caused by free radicals.
The biologically active chemical constituents of Withania somnifera (WS) include alkaloids (isopelletierine, anaferine, cuseohygrine, anahygrine, etc.), steroidal lactones (withanolides, withaferins) and saponins. Sitoindosides and acylsterylglucosides in Ashwagandha are anti-stress agents. Active principles of Ashwagandha, for instance the sitoindosides VII-X and Withaferin-A, have been shown to have significant anti-stress activity against acute models of experimental stress. Many of its constituents support immunomodulatory actions. The aerial parts of Withania somnifera yielded 5-dehydroxy withanolide-R and withasomniferin-A.
Ashwagandha has been used as a Rasayana. The root of Ashwagandha is regarded as tonic, aphrodisiac, narcotic, diuretic, anthelmintic, astringent, thermogenic and stimulant. The root smells like horse (“ashwa”), that is why it is called Ashwagandha (on consuming it gives the power of a horse). It is commonly used in emaciation of children (when given with milk, it is the best tonic for children), debility from old age, rheumatism, vitiated conditions of vata, leucoderma, constipation, insomnia, nervous breakdown, goiter etc. The paste formed when roots are crushed with water is applied to reduce the inflammation at the joints. It is also locally applied in carbuncles, ulcers and painful swellings. The root in combination with other drugs is prescribed for snake venom as well as in scorpion-sting. It also helps in leucorrhoea, boils, pimples, flatulent colic, worms and piles. The Nagori Ashwagandha is the supreme among all Ashwagandha varieties. Maximum benefit appears when fresh Ashwagandha powder is used.
The leaves are bitter and are recommended in fever, painful swellings. The flowers are astringent, depurative, diuretic and aphrodisiac. The seeds are anthelmintic and combined with astringent and rock salt remove white spots from the cornea. Ashwagandharishta prepared from it is used in hysteria, anxiety, memory loss, syncope, etc. It also acts as a stimulant and increases the sperm count.

GINKGO BILOBA EXTRACT
Ginkgo biloba L. (Ginkgoaceae) is an ancient tree growing in China for centuries; however, it was only during the last couple of decades that its true value was recognized, being considered sacred for its health-promoting properties. The medical interest in western G. biloba has increased since the 1980s, due to its potent action on cardiovascular system and cerebral vascular activity. In recent decades, in Western countries, the concentrated extracts of the leaves have been marketed as herbal medicines due to the presence of bioactive components (e.g., terpenoids, polyphenols, organic acids, carbohydrates, essential fatty acids, inorganic salts and amino acids), and to the capacity to increase microcirculation in brain (with the supply of oxygen and nutrients) and in body extremities. Thus, it can be useful in the improvement of symptoms of poor memory, impaired mental concentration, particularly in the elderly, for whom this function is sometimes lowered. It also has positive effects in certain situations such as tinnitus (ringing) and hearing capacity altered, bringing also cardiovascular protection due to the ability to prevent platelet aggregation and thrombus formation. Furthermore, due to the antioxidant properties it has been used in Alzheimer's patients.
Brain is particularly prone to damage by reactive oxygen species (ROS) and reactive nitrogen species (RNS) due to five main reasons: the high oxygen required by this organ; the abundance of redox-active metals; the relative deficit in antioxidant systems; the presence of great amount of oxidizable polyunsaturated fatty acids and catecholamines; and the fact that neurons are post-mitotic cells with relatively restricted replacement by progenitor cells during lifetime. Thus, a variety of mechanisms of neuronal degeneration in Alzheimer diseases has been proposed, including formation of free radicals, oxidative stress, mitochondrial dysfunction, inflammatory processes, genetic factors, environmental impact factors, apoptosis, among others. Different studies reported that neuronal earliest changes and pathological features of this disease are related to oxidative damage (with a very high input of oxidative stress), mainly in the development of neuritic abnormalities. In fact, paired helical filaments are more often found in neurites with membrane abnormalities, which is indicative of extensive lipid peroxidation . Moreover, crosslinking of proteins by oxidative processes may lead to the resistance of the lesions to intracellular and extracellular removal even though when they are extensively ubiquitinated; this resistance of neurofibrillary tangles to proteolysis might play an important role in the progression of the degenerative disease. In this context, the use of polyphenols may be useful, since they increase the cellular stress response and improve mitochondrial respiration, thus allowing the neuron to counteract free radical-induced damage and produce the ATP necessary to maintain the normal membrane potential.
Taking into account the described relation between antioxidants and Alzheimer's disease, and considering the use of G. biloba in the mentioned pathology, the antioxidant activity of different dietary supplements (syrup and several pills) was evaluated and compared to the leaves infusion, aqueous and methanolic extracts. Furthermore, G. biloba was chemically characterized in nutritional and bioactive Components.
Ginkgo biloba is chemically composed of Macronutrients such as moisture, proteins, fat, carbohydrates and ash; free sugar; Organic acids and tocopherols.

MANJISTHA EXTRACT
Rubia cordifolia L. is a climbing or scrambling herb, with red rhizomatous base and roots. It is an essential raw drug for the traditional herbal formulations such as aswagandharistam, gulguluthikthkarishtam, jaatyaadi ghrita, madhookasavam, majishthaadi taila, useerasavam etc. It is a member of Rubiaceae family, distributed in hilly tracts of India up to 3750m. commonly known as ‘Indian Madder’ and sold under the trade name ‘manjistha’. The plant has other vernacular names such as manjit in Hindi, chitravalli in Kannada, ceevalli in Tamil, manchatti and manjatti in Malayalam and manderti in Telengu.
Manjistha is considered as tonic, antitussive and useful in chronic low fevers. Decoction from roots is prescribed to cure jaundice, paralytic affections, urinary troubles, amenorrhea and to the mother after delivery for cleansing and shrinking of the uterus. The root decoction is effective to regulates menstruation cycles.. It is proved that various root extracts of R. cordifolia are has astringent, themogenic, febrifuge, antidysenteric, antihelmintic, galactopurifier, ophthalmic, and rejuvenating effect. It is used to cure tuberculosis and intestinal ulcer. In modern pharmacopeia, R. cordifolia is reported to be active against a diversified panel of cancer cell lines, such as P388, L1210, L5178Y, B16 melanoma, Lewis lung carcinoma, and sarcoma180. The macroscopic and microscopic description of a medicinal plant is the first step towards identification and determination of purity. However, such an attempt has not been made on R. cordifolia so far. In the present communication we devoted our effort to document the pharmacognostic features of the entire plant to identify the plant in its crude form.
Chemical constituents in Rubia cordifolia Different classes of bioactive compounds such as anthraquinones and their glycosides, naphthoquinones and glycosides, terpenes, bicyclic hexapeptides, iridoids,11 carboxylic acids (malic, citric, quinic, rosmarinic acids) and saccharides (xylose, ribose, fructose, glucose, sucrose, primverose) were isolated from various parts of R. cordifolia. The roots contain a mixture of purpurin, munjistin, small amounts of xanthopurpurin and pseudopurpurin.

SIGRU
Sigru history dates back to 4,000 years ago, with earlier civilizations using it to help alleviate anemia, arthritis, joint pain and constipation.
It biological structure is similar to sulforaphane and appears to be protective when taken as supplement.The most amazing fact about Sigru is that it is a storehouse of nutrients and medicinal chemicals. Sigru tree is rich in nutrients such as minerals, fiber and proteins that can play essential role in human nutritional consumption.
Sigru dry leaves extract contains 9 times proteins than yogurt, 10 times vitamin A than carrot, 7 times more vitamin C than oranges, 17 times more calcium than milk 25 times iron than spinach and 15 times potassium than bananas, Because of rich in proteins source Sigru leaves extract are suggested by doctors and nutritionists as well. Sigru leaves are a storehouse of nutrients. The leaves of Sigru are rich in minerals like copper, potassium, iron, magnesium, zinc and calcium. Vitamins like beta carotene of vitamin A, vitamin B such as folic acid, pyridoxine and nicotinic acid, vitamin C, D and E also present in Sigru.
Sigru is one of the effective supplement due to its powerful antioxidant properties. In addition, Sigru has the ability to influence a variety of body processes positively, including eyesight, respiration, digestion and toxin filtration.
It Helps protect diabetes patients from retinopathy: Retinopathy is caused by the inflammation of the blood vessels in the eyes, which may lead to fluid leakage. If left untreated, retinopathy may advance into complete blindness.Sigru may help stop retinopathy by regulating blood sugar in diabetes patients and protecting the retina from inflammation. This is mainly because of Sigru's high antioxidant content.
It has been observed that Sigru may help regulate blood pressure due to increased antioxidant potential and vasodilation.In asthma: As a bronchodilator, Sigru relaxes the bronchi and bronchioles, increasing air passage into the lungs. The antibacterial properties of Sigru also help eliminate external materials that may trigger asthma.
Sigru helps kidneys from oxidative toxins: Your kidneys are responsible for filtering out toxins and dangerous materials in the body. When the kidneys are damaged, this means that the body's ability to detoxify becomes compromised.Sigru can help protect the kidneys from nephrotoxicity caused by regular dependency on medicines.
Sigru Prevents liver damage: The high levels of polyphenols in Sigru help protect the liver from oxidation and toxicity. It can normalize liver enzymes as well, increasing the protein content in the liver. Promotes wound healing: Sigru contains blood-clotting properties, which may reduce the healing time of wounds, scrapes and scratches. In addition, the antibacterial and antiviral properties of Sigru may also prevent possible wound infections.
The high levels of vitamins, minerals and antioxidants in Sigru promote the smooth functioning of numerous body organs, improving your overall health in the process. It helps protect you from free radicals, or molecules that may trigger numerous chronic diseases. Sigru also has the ability to support brain health and suppress inflammation.
Sigru is believed to have many benefits and its uses range from health and beauty to helping prevent and cure diseases. The benefits of Sigru include: Protecting and nourishing skin and hair, treating edema, Protecting the liver, Preventing and treating cancer, treating stomach complaints, fighting against bacterial diseases, making bones healthier, treating mood disorders, Protecting the cardiovascular system, helping wounds to heal, treating diabetes, treating asthma, protecting against kidney disorders, reducing high blood pressure, improving eye health, treating anaemia and sickle cell disease.
In addition to above mentioned benefits, it also helps to:
• Regulates blood pressure and cholesterol level.
• Regulates blood sugar level and help controlling diabetes.
• Enhances immune system.
• Increases energy, stamina, vigour and vitality.
• Helps prevent degenerative arthritis, relieve rheumatism and osteoarthritis.
• Remove toxins out and nourishes cells.
• Provides relief in constipation and indigestion.
• Natural anti-aging benefits.
• Supports normal hormone levels, promotes mental and emotional balance,
reduce oxidative stress, is a free radical scavenger.
• Promotes normal liver function.
• Triggers metabolism.
• May helps to increases sexual energy.
• In helps in purifying blood due to its anti-microbial action.
• It helps in healthy regulation of the nervous system, reducing depression,
stress and brain shrinkage.
• Improves mental alertness and concentration, protects from nerve
damage, restore and rebuild nerve tissue.
Sigru is a commonly used plant and a rich source of nutrients and antioxidants.
Sigru has great potential to become a far more important food source as it is a rich source of vitamins and polyphenols.

SHATAVARI EXTRACT (Asparagus racemosus)
Asparagus racemosus is a plant used in traditional Indian medicine (Ayurveda) generally named as shatavari. The root is used to make medicine. However, there should be no confusion between asparagus racemosus with Asparagus officinalis, which is the type of asparagus that is commonly eaten as a vegetable. People use asparagus racemosus for upset stomach (dyspepsia), constipation, stomach spasms, and stomach ulcers. It is also used for fluid retention, pain, anxiety, cancer, diarrhea, bronchitis, tuberculosis, dementia, and diabetes. Some people use it to ease alcohol withdrawal. Women use asparagus racemosus for premenstrual syndrome (PMS) and uterine bleeding; and to start breast milk production. Asparagus racemosus is also used to increase sexual desire (as an aphrodisiac).
Methanolic extract of Asparagus racemosus significant antidepressant-like activity almost certainly by inhibiting MAO-A and MAO-B; and through interaction with adrenergic, dopaminergic, serotonergic and GABAergic systems.
Methanolic extract of roots shatavari show significant antitussive activity on sulphur dioxide- induce cough in mice.The cough inhibition of 40% and 58.5%, respectively, was comparable to that of 10-20mg/kg of codeine phosphate observed 36% and 55.4%, respectively.
Asparagus racemosus causes an inhibitory effect on release of gastric hydrochloric acid and protects gastric mucosal damage and found to be an effective antiulcerogenic agent.
The aqueous extract of Asparagus racemosus reversed the effects of cisplatin on gastric emptying and also normalized cisplatin-induced intestinal hyper motility.
Ethanol extract of whole plant Asparagus racemosushave Anti-diarrhoeal and Analgesic properties. In another study the effect of aqueous and ethanol extract of Asparagus racemosus for its antidiarrhoealpotential against experimental models of diarrhoea in Albino Wistar rats.
An aqueous solution of the crude alcoholic extract of the roots exhibited an inhibitory effect of the growth of Entamoeba histolytica.
Methanol extract of the roots of Asparagus racemosus have antibacterial efficacy against Escherichia coli, , Shigella sonnei, Shigella dysenteriae, Shigella flexneri, Vibrio cholerae, Salmonella typhi, Salmonella typhimurium, Bacillus subtillis, Pseudomonas putida and Staphylococcus aureus , and also show the spectrum of inhibition on Staphylococcus aureus, Bacillus subtillis, ,Pseudomonas putida, Staphylococcus werneri , Proteus mirabilis, Pseudomonas aeruginosa.
Administration of 200 mg/kg (i.p.) leading to substantial reductions in skin thickness,tissue weight and also inflammatory cytokine production, neutrophil-mediated myeloperoxidase activity, and various histopathological indicators. Additionally Angiotensin converting enzyme have effective to reducing inflammatory damage induced by chronic TPA exposure and a significant inhibition of vascular permeability induced by acetic acid.

PUNARNAVA EXTRACT
Boerhavia diffusa (BD) Linn. (Nyctaginaceae) is a well-known medicinal plant in traditional Indian medicine as well as other parts of world, for example, Southern American and African continent. It is generally known as punarava.Its various parts and especially roots have been used for gastrointestinal, hepatoprotective, and gynecological indications in above mentioned parts of the world and also throughout India. In ayurvedic texts, more than 35 formulations of different types contain it as major ingredient.
In Ayurveda, BD has been classified as “rasayana” herb which is said to possess properties like antiaging, reestablishing youth, strengthening life and brain power, and disease prevention, all of which imply that they increase the resistance of the body against any onslaught, in other words, providing hepatoprotection and immunomodulation.
It occupied a reputed position of having valuable medicinal properties in both folk and classical streams of indigenous medicinal systems. It is pungent, astringent and bitter in taste; the various parts of the plant are used in the treatment of cancer, jaundice, dyspepsia, inflammation, enlargement of spleen, abdominal pain and as an anti-stress agent.
Punarnava leaf juice is used in the eyes for topical application. Punarnava leaves vegetable is consumed to reduce edema . Leaf juice with honey, dropped into the eyes for chronic ophthalmia.The leaves are useful in dyspepsia, tumors, spleen enlargement; abdominal pains According to Unani system of medicine, the leaves are appetizer, alexiteric, useful in opthalmia, in joint pain.The leaves of B.Diffusaare used as a green vegetable in many parts of India. It cures ulcers of cornea, night blindness and helps to bring back virility in men.
Seeds are tonic expectorant, carminative, useful in lumbago, scabies [7]. The seeds are considered as promising blood purifier11.Seeds are used as energizer and for help in digestion.
The roots are reputed to be diuretic and laxative and are given for the treatment of anasarca, ascites and jaundice[22]. The root juice is used to cure asthma, urinary disorders, leucorrhea, rheumatism, and encephalitis [23]. B. Diffusa roots have been widely used for the treatment of dyspepsia, jaundice, enlargement of spleen, and abdominal pain, and as an anti-stress agent[24]. The worldwide use of B. Diffusaroots to treat liver disorders was validated when researchers demonstrated, in 1980 and 1991 that its root extract had antihepatotoxic properties.
Punarnava is also valued in ophthalmic disorders, the Sharangadharasamhita recommending a collerium (anjana) for itching, prepared by mixing the churna with milk; mixed with honey to treat ophthalmic discharges; with ghee for corneal wounds; with taila for poor vision; and with rice water (kanjika) for night blindness.

GOKSHURA EXTRACT
TT is commonly known as Gokshur (Sanskrit); puncture vine, land (or small) caltrops (English); Gokharu (Hindi); Bethagokharu or Nanagokharu (Gujarathi); Nerinjil (Tamil); and Khar-ekhusak khurd (Urdu). It is distributed along a wide geographic perimeter. It is found all over India up to 11,000 ft in Kashmir, Ceylon, and all warm regions of both hemispheres. It is a common weed of the pasture lands, road sides, and other waste places, chiefly in hot, dry, and sandy regions including West Rajasthan and Gujarat in India.
The whole aboveground plant (herb) of TT is used for medicinal purposes including whole or cut stems, leaves, flowers, and fruits. It has no specific smell or taste. However, according to the monograph of the World Health Organization, the fruits are the basic material for use. Overall, the fruit chemical composition has been examined most often, the shoots less often, and the separate different vegetative parts rarely. Several groups of NP in TT were established: steroids, saponins, flavonoids, sterols, Harman alkaloids, minerals, lignan amides, and cinnamic acid amides18,31. The basic plant medicinal properties are defined by the presence of steroidal saponins having a furostanol or spirostanol nucleus, glycosylated in 3 and/or 26 positions with linear and branched glycosidic units.They are specific for the species’ chemical composition.
It is used in folk medicines as a tonic, aphrodisiac, palliative, astringent, stomachic, antihypertensive, diuretic, lithotriptic, and urinary disinfectant. The dried fruit of the herb is very effective in most of the genitourinary tract disorders. It is a vital constituent of Gokshuradi Guggul, a potent Ayurvedic medicine used to support proper functioning of the genitourinary tract and to remove the urinary stones. TT has been used for centuries in Ayurveda to treat impotence, venereal diseases, and sexual debility. In Bulgaria, the plant is used as a folk medicine for treating impotence. In addition to all these applications, the Ayurvedic Pharmacopoeia of India attributes cardiotonic properties to the root and fruit. In traditional Chinese medicine, the fruits were used for treatment of eye trouble, edema, abdominal distension, emission, morbid leukorrhea, and sexual dysfunction. TT is described as a highly valuable drug in the Shern-Nong Pharmacopoeia (the oldest known pharmacological work in China) in restoring the depressed liver, for treatment of fullness in the chest, mastitis, flatulence, acute conjunctivitis, headache, and vitiligo. In Unani medicine, TT is used as diuretic, mild laxative, and general tonic.
It has been found that utilization of the above-mentioned method with combinations of products results in a dehydrated composition that is homogeneous and resistant to separation of the components. That is, the ratio of the components is retained in the dried product. The method produces a dehydrated product with a density similar to that obtained by spray-drying / sun drying and the like, but with retention in heat-labile constituents similar to that obtained via freeze-drying.
Products which may be utilized in the combinations for drying include but are not limited to berries, fruits, herbs, vitamins, barks, roots, nuts, legumes, and extracts or purified extracts of berries, fruits, herbs, vitamins, barks, roots, nuts, or legumes including including Mangosteen, Safed Musli,Siberian ginseng, Elderberry, Bilberry, Ashwagandha, Ginkgo Biloba ,Manjistha Sigru, Shatavari, Punarnava and Gokshura.
The extracts of any of aforesaid ingredients may be liquefied by any process, filtered or unfiltered and combined. In some embodiment, the extracts are combined in a ratio of less than 1% to greater than 99% in the liquid form. The liquid combinations are then dried using the methods of the invention to form a gel, a film, a flake, or a powder that retains the original homogeneity of the liquid. The form of the dried product depends on several factors, such as composition of original components, temperature of drying, residence time on the dryer, moisture content of the product, and polysaccharide content of the product. For example, products with higher polysaccharide content tend to result in more filmlike products. In some embodiments of the invention, the form of the dried product may be controlled by controlling the above-mentioned factors. For example, if a film is desired, then polysaccharide may be added to the liquid composition. Films may be converted to flakes or powders, and flakes may be converted to powders with further processing of the dried product.
Homogeneity of the product may be determined by methods known to those skilled in the art. It is known in the art that dry blends containing different combinations of food, herbs, supplements or extracts of food or herbs can experience separation of constituents due to different densities even when particle size is similar. Such separations occur, for example, during transport of the mixtures. The present combinations of dried blends, however, do not undergo a separation of constituents under these circumstances. In some embodiments, the homogeneity of the dried product is retained for at least about three years.
The dried blends of the present invention can be used in a variety of applications. The combinations of ingredients or purified extracts of said ingredients remain homogeneous in dehydrated form will improve the ease of formulations and standardize the constituents of the product. Standardization of constituents will improve the dependability of sensory attributes, nutrients and bioactivities of the combinations. Bioavailability of nutrients may be improved in the presence of aloe and the nutritional value of the foods, supplements or extracts. The dried products may be reconstituted with water. The dried blends can be used as a preformulation for the preparation of food, supplemental, therapeutic or cosmetic products.
As to the preparation of capsules of the dried blends, for example, as nutritional supplements, the dried blends of the present invention are suitable for use in an encapsulation process since they are homogeneous and would not encounter difficulties with ingredient flow that may be present in nonhomogeneous mixtures.
The dried blends of the present invention may be used in compositions for various uses, such as therapeutic, cosmetic, and nutritional uses. For example, the dried blends may be formulated in a composition that contains a therapeutic agent. The therapeutic agent may be present either as part of the dried blend, or as part of a further composition.
As noted above, the dried composition of the present invention can be present in various drug delivery system, including gels, films, flakes, and powders. The form of the dried composition will inform the addition of other components for a particular use. If necessary the composition may be milled at any suitable stage of the process. A suitable sterilization procedure may also be included if necessary. Alternatively raw materials are obtained in sterile condition and the compositions are produced aseptically.
In an another embodiment of the invention, the end-product(s) is suitable for use in the form of powder, granules, suspension, tablets or capsules etc.
One more embodiment of the invention, relates to a process for the preparation of herbal health protective, promotive and preventive nutraceutical composition(s) useful as food supplements to ameliorate the general health with optimum nutrients and also help to control the blood sugar level and disease related problems, the said process comprising:
a. selecting seed from the ingredients including Mangosteen, Safed Musli,Siberian ginseng, Elderberry, Bilberry, Ashwagandha, Ginkgo Biloba ,Manjistha Sigru, Shatavari, Punarnava and Gokshura.
b. drying the ingredients for 2 to 15 minutes under microwave conditions having frequency 1500–2500 MHz, powdering the roasted seeds to a mesh size of 50–400 and mixing the ingredient powders in definitive proportions.,
c. obtaining powder or extract of the said ingredients including Mangosteen, Raspberry, Siberian Ginseng, Elderberry, Maca Root, Sour cherry, Ganoderma, Sigru,and Black currant; and
d. drying the extract to obtain a residue, mixing the plants extract residue with the base product to get the final nutraceutical product(s)
e. and optionally adding some additives selected from conventional preservatives and / or flavoring agents to obtain nutraceutical product(s).

In another embodiment of the invention, the roasted seeds are powdered separately to pass through sieves having mesh size ranging from 50 to 400.
In another embodiment of the invention, the amount of dried ingredient powders are mixed in various proportions ranging up to 40% by weight and parts of plants used are selected from roots, fruits, seeds, leaves, wood and whole plant of herbs/medicinal plants ranging up to 40% by wt. are selected for use in the nutraceutical product(s).
In yet another embodiment of the invention, the said powdered ingredient mixture is extracted with aqueous alcohol in the range of 5 to 95% v/v thrice for 5 to 48 hours, at temperature ranging from 20 to 50° C.
In yet another embodiment of the invention, the alcohol is selected from methanol, ethanol, propanol, isopropanol and butanol.
In yet another embodiment of the invention, the said solvent from combined extractives is removed under reduced pressure ranging from 10 to 150 PSI at temperature ranging from 20 to 80° C. and the viscous residue thus obtained is called as plants extract.
In yet another embodiment of the invention, the plants extract is suspended in ethanol-water mixture from 0 to 90% v/v in the ratio ranging from 10 to 30% by stirring for 5 to 60 minutes.
In yet another embodiment of the invention, the mixture of ingredient powder’s are mixed thoroughly in a mixer grinder for a period of ranging from 5 to 60 minutes.
In yet another embodiment of the invention, the mixture is dried for a period of ranging from 5 to 50 hours at temperature ranging from 20 to 50° C.
In yet another embodiment of the invention, the amount of optional additives used are in the range of 0.5 to 4% by wt.
In yet another embodiment of the invention, the dried combination of the pulp, pericarp, bark and roots of the ingredients are repeatedly mixed thoroughly in a mixer grinder for a period of ranging from 5 to 60 minutes and the powder thus obtained is used to prepare final nutraceutical(s).
In yet another embodiment of the invention, the said dried ingredients are mixed with in the ratio ranging up to 90% and more by wt. excluding the weight of additives like preservatives and / or flavoring agents
In yet another embodiment of the invention, the said said composition is prepared by a process comprising the steps of obtaining powder or extract of the ingredients; drying the extract to obtain a residue for each ingredient; and mixing the residue in definite proportion with preservative and flavoring agents.
In yet another embodiment of the invention, the said n formulation is prepared by a process comprising the steps of Grinding the dried ingredients independently; Extracting the ingredient(s) with aqueous alcohol in the range of 5 to 95% v/v water to alcohol for 5 to 48 hours at a temperature of 20 to 50° C.; and Filtered and distilled said solvents under reduced pressure at 20 to 80° C. in order to obtain extract of the ingredients; and finally mixing the extracts of all the ingredients in definite proportion with preservative and flavoring agents.
In yet another embodiment of the invention, the said composition is prepared by a process comprising the steps of grinding or powdering the dried ingredient(s); extracting the crushed or powdered herb with aqueous alcohol in the range of 5 to 95% v/v water to alcohol for 5 to 48 hours at a temperature of 20 to 50° C d, distilling said alcohol under reduced pressure at 20 to 80° C. in order to obtain extract the ingredient; andmixing extracts of all the ingredients in definite proportion with preservative and flavoring agents to obtain the product.
In yet another embodiment of the invention, the said extraction is carried out three times under same condition and distilled the combined extracts for efficient extraction.
In yet another embodiment of the invention, alcohol is selected from the group consisting of methanol, ethanol, iso-propanol, and butanol.
In yet another embodiment of the invention, the nutraceutical formulations, as herein described for the composition, methodology, preparation of base material for nutrition and fortified with selected herbs/medicinal plants in the form of powders/extracts to get the value added end nutraceutical product(s) which may be used as health protective, promotive, food supplements to ameliorate the general health of the individual and to control chronic ailments in the form of powder, granules, syrups, suspension, tablets or capsules etc.
Generally, the therapeutic agents used in the disclosure are a dministered to a human or animal in an effective amount. Generally, an effective amount is an amount effective to either (1) reduce the symptoms of the disease sought to be treated or (2) induce a pharmacological change relevant to treating the disease sought to be treated. For bacterial infections, for example, an effective amount includes an amount effective to: reduce or eliminate the bacterial population; slow the spread of infection; or increase the life expectancy of the affected human or animal.
Therapeutically effective amounts of the therapeutic agents can be any amount or doses sufficient to bring about the desired effect and depend, in part, on the condition, type and location of the infection, the size and condition of the patient, as well as other factors readily known to those skilled in the art. The dosages can be given as a single dose, or as several doses, for example, divided over the course of several weeks.
Use of the present compositions may also be in food products, including those envisioned for use as a dietary supplement such as a health bar. Beverage compositions using dried blends of the present invention may comprise a beverage member such as water, fruit juice, tea solids, milk solids, fruit flavors, botanical flavors, and mixtures thereof. Water may be included in the compositions of the present invention, particularly wherein the compositions are beverage compositions. As used herein, the term “water” includes the total amount of water present in the composition. “Water” includes water from flavor agents, sugar syrups, and other sources, e.g., gum solutions. The term “tea solids” as used herein means solids extracted from tea materials including those materials obtained from the genus Camellia including C. sinensis and C. assaimica, for instance, freshly gathered tea leaves, fresh green tea leaves that are dried immediately after gathering, fresh green tea leaves that have been heat treated before drying to inactivate any enzymes present, unfermented tea, instant green tea, and partially fermented tea leaves. Green tea materials are tea leaves, tea plant stems, and other plant materials that are related and which have not undergone substantial fermentation to create black teas. Members of other families of tea plants can also be used. Mixtures of unfermented and partially fermented teas can be used. Tea solids for use in beverages of the present invention can be obtained by known and conventional tea solid extraction methods. Tea solids may comprise caffeine, theobromine, proteins, amino acids, minerals and carbohydrates.

Dietary foods can be made with the dried compositions to meet special dietary needs, for example, of persons who are obese, diabetic, or hypercholesterolemic. The present compositions can be used alone or in combination with drug therapy, nutritional therapy, or other therapy. Combinations of food or beverage products made with the compositions can be used as part of a total dietary management regimen, based on one or more of these products, containing the compositions alone or in combination with one or more of the above-mentioned ingredients, to provide one or more of the above-mentioned benefits.

EXAMPLES
The following example is provided for illustrative purposes only and are not intended to limit the scope of the invention.
In an example the ingredients are mixed in the following proportions for nutraceutical composition comprising:
A dried powder of ingredients :
Serial number Ingredients Wt(mg) in net wt of 350mg
1 Mangosteen Extract 56
2 Siberian Ginseng Extract 26
3 Safed Musli Extract 18
4 Elderberry Extract 27
5 Bilberry Extract 31
6 Ashwagandha Extract 41
7 Ginkgo Biloba Extract 24
8 Manjistha Extract 29
9 Sigru 24
10 Shatavari Extract 21
11 Punarnava Extract 27
12 Gokshura Extract 26

The embodiments are manufactured through a process, by way of dispensing wherein specific amounts of raw materials from bulk container are weighed and transferred to smaller unit which is required for manufacturing of a specific batch; sifting wherein all the dispensed material are shifted for so that undesirable undersized portions of the raw materials are separated; blending wherein the materials are added to cone blender mixer; capsule filling wherein the hard pieces of capsule can be filled with material by using different filling machine; capsule polishing and finally sent for inspection. Thereafter, products are packed and kept for filling of 120 capsules per bottle by using different filling machine such as Lilly capsule filling process, Osaka model 180 capsule filling machine etc. finally, this bottle are sent for batch coding.
The above detailed description is to illustrate the specific best-mode embodiment of the present invention, but it is not intended to be limiting. Numerous modifications are possible within the scope of the present invention. The present invention is set forth in the accompanying claims.

, Claims:We Claim:

1. A nutraceutical composition comprising:
Mangosteen Extract(56mg);
Safed Musli Extract(26mg);
Siberian ginseng(18mg);
Elderberry Extract(27mg);
Bilberry Extract(31mg);
Ashwagandha Extract(41mg);
Ginkgo Biloba Extract(24mg);
Manjistha Extract(29mg);
Sigru(24mg);
Shatavari Extract(21mg);
Punarnava Extract(27mg); and
Gokshura Extract(26mg)
with pharmaceutically acceptable salts, preservative and flavoring agents to prepare different drug delivery system.

2. The nutraceuticalcomposition as claimed in claim 1, wherein the preservatives are conventional pharmaceutically acceptable salts and carriers.

3. The nutraceutical composition as claimed in claim 1, wherein the flavoring agents are conventional pharmaceutically acceptable salts, esters and carriers.

4. The nutraceutical composition as claimed in claim 1, wherein composition is prepared by a process comprising the steps of:
a) Grinding the dried ingredients independently;
b) Extracting the powdered herb(s) with aqueous alcohol in the range of 5 to 95% v/v water to alcohol for 5 to 48 hours at a temperature of 20 to 50° C.;
c) Filtering and distilling said solvents under reduced pressure at 20 to 80° C. in order to obtain extract of the ingredients;
d) dispensing wherein specific amounts of raw materials from bulk container are weighed and transferred to smaller unit which is required for manufacturing of a specific batch;
e) sifting wherein all the dispensed material are shifted for so that undesirable undersized portions of the raw materials are separated;
f) blending wherein the materials are added to cone blender mixer; and
g) Mixing the extracts of all the ingredients in definite proportion with preservative and flavoring agents.

5. The nutraceuticalcomposition as claimed in claim 4, wherein the extraction is carried out three times under same condition and distilled the combined extracts for efficient extraction.

6. The nutraceutical composition as claimed in claim 4, wherein said alcohol is selected from the group consisting of methanol, ethanol, 2-propanol, and butanol or a mixture thereof.

Dated this 3rd day of April, 2023

BISWAJIT SARKAR (IN/PA/152)
APPLICANT’S ATTORNEY