Claims:1. A process for the preparation of a composition, comprising:
(a) oxyresveratrol;
(b) at least one polymer;
(c) at least one surfactant;
(d) at least one co-surfactant,
wherein oxyresveratrol is encapsulated in the at least one polymer, the process comprising the steps of:
1) contacting oxyresveratrol and the at least one polymer with at least one solvent to obtain an organic phase;
2) contacting the at least one surfactant and the at least one co-surfactant with water to obtain an aqueous phase;
3) contacting the organic phase with the aqueous phase to obtain an emulsion; and
4) removing the at least one solvent from the emulsion to obtain a first mixture;
5) lyophilizing the first mixture to obtain the composition.
2. The process as claimed in claim 1, wherein: (i) contacting oxyresveratrol and the at least one polymer with at least one solvent to obtain an organic phase is carried out at a temperature in the range of 25 – 40 °C, over a period in the range of 10 – 30 minutes; (ii) contacting the at least one surfactant and the at least one co-surfactant with water to obtain a aqueous phase is carried out at a temperature in the range of 25 – 40 °C, over a period in the range of 5 – 15 minutes; (iii) contacting the organic phase with the aqueous phase to obtain an emulsion is carried out at a temperature in the range of 25 – 40 °C, over a period in the range of 15 – 40 minutes with simultaneous homogenization; (iv) removing the at least one solvent from the emulsion to obtain the first mixture is carried out by evaporating the solvent by stirring the emulsion at a temperature in the range of 30 – 60 °C, over a period in the range of 15 – 45 minutes; (vi) lyophilizing the first mixture to obtain the composition is carried out at a temperature in the range of -65 – -75 °C for a period in the range of 15 – 20 hours.
3. The process as claimed in claim 1, wherein the at least one surfactant to oxyresveratrol weight ratio is in the range of 1:200 – 1:850.
4. The process as claimed in claim 1, wherein the at least one surfactant to the at least one polymer weight ratio is in the range of 1:10 – 1:60.
5. The process as claimed in claim 1, wherein the at least one surfactant to the at least one co-surfactant weight ratio is in the range of 1: 02 – 1:1.
6. The process as claimed in claim 1, wherein the at least one polymer is selected from the group consisting of poly (D, L – lactide-co-glycolide) (PLGA), polylactide (PLA), polyglycolide (PGA), and copolymers thereof.
7. The process as claimed in claim 6, wherein the poly (D, L – lactide-co-glycolide) (PLGA) is selected from the group consisting of poly (D, L – lactide-co-glycolide) (PLGA) lactide:glycolide 50:50 (PLGA 50:50),poly (D, L – lactide-co-glycolide) (PLGA) lactide:glycolide 75:25 (PLGA 75:25), and combinations thereof.
8. The process as claimed in claim 6, wherein the poly (D, L – lactide-co-glycolide) (PLGA) has a molecular weight in the range of 20,000 – 1,20000.
9. The process as claimed in claim 1, wherein the at least one surfactant is selected from the group consisting of polyvinyl alcohol (PVA), and combinations thereof.
10. The process as claimed in claim 1, wherein the at least one co-surfactant is selected from the group consisting of D-a-tocopherol polyethylene glycol 1000 succinate (TPGS), Poloxamer 407, and combinations thereof.
11. The process as claimed in claim 1, wherein the at least one solvent is selected from the group consisting of acetone, dichloromethane, ethanol, ethyl acetate, and combinations thereof.
12. The process as claimed in claim 2, wherein the homogenization is carried out by stirring at a speed in the range of 1000 – 15000 rpm.
13. The process as claimed in claim 1, wherein the at least one polymer to oxyresveratrol ratio is in the range of 1:2 – 1:8.
14. The process as claimed in claim 1, wherein the organic phase to aqueous phase volume ratio is in the range of 1:1 – 1:10.
15. The process as claimed in any of the preceding claims 1 – 14, wherein the process is carried out on scale in the range of microgram scale to kilogram scale.
16. A composition prepared by a process as claimed in any of the claims 1 – 14, comprising:
(a) oxyresveratrol;
(b) at least one polymer;
(c) at least one surfactant;
(d) at least one co-surfactant,
wherein oxyresveratrol is encapsulated in the at least one polymer.

, Description:AS ATTACHED