F0RM-3A
THE PATENTS ACT, 1970
COMPLETE
SPECIFICATION
SECTION 10
TITLE A PROCESS FOR THE PREPARATION OF A WATER-SOLUBLE
CRYSTALLINE AYURVEDIC COMPOSITION FROM SAWANA FOR THE TREATMENT OF ALLERGIES AND HISTAMINERGIC REACTIONS.
APPLICANT : - BAN LABS LIMITED, DR.VTKRAM SARABHAI NAGAR,GONDAL ROAD
(SOUTH), RAJKOT 360 004, GUJARAT STATE,INDIA
The following Specification particularly describes and ascertains the nature of this invention and the manner in which it is to be performed : -

Present invention relates a to a process for the preparation of a water-soluble crystalline ayurvedic composition from sawana for the treatment of allergies and histaminergic reactions. This method constituting of dried herbal medicinal material 'Sawana' subject to a range of heat which transforms and converts the medicinal herbs into a water soluble composition without sacrificing its anti-allergic and anti-histaminergic properties.
There are several compositions available in Indian market to treat the allergic reactions and histaminergic out breaks. These are majoritily of allopathic nature. Even though in the Ayurvedic texts a word "allergy" or its counterpart is not to be found, there is ample evidence in these texts to show that 'Poorvacharyas' were aware of such type of dieseases and symptoms. Therefore remedies are suggested in Ayurvedic Samhitas to treat these conditions. These conditions are treated with different types of drugs prepared by different methods like 'Ghruta Vidhi', 'Choorna Kalpana' etc. Allopathic anti-histamic drugs which are manufactured as 'blocking agents' to histamine. They are to be used before the allergic breakout. They are of little value after the release of histamine to cause the allergic episode.
In short present day anti-histaminics and anti-allergy drugs are based on the fact that they are designed to block the release the histamine or to block its receptor so that the action does not take place. In fact, they are similar substances to histamine having structural similarity so that they occupy the same receptors where normally histamine molecule occupies. Therefore, present day anti-histaminics or anti-allergy agents are of little use after the allergic reaction has taken place.
Object of the present invention, therefore, aims at developing an anti-histaminic, anti-allergic composition from the Ayurvedic herbs Sawana on the principles of Ayurvedic "Aushadhi Nirman" but not as a copy of formulation mentioned in Ayurvedic extracts.
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According to still another object, it is to make available to the public in any suitable form like tablet, capsule, syrup, or even injectible so as to reach all the strata and nook and corners of our country.
According to our invention, therefore, a process for the preparation of a water-soluble crystalline ayurvedic composition from sawana for the treatment of allergies and histaminergic reactions comprising of collecting 'Sawana' single medicinal plant from jungle areas, the said plant is shed dried till constant weight of the three consecutive samples are identical, this plant is burnt to white ash within a heat range between 280 to 400°C for about 2 to 3 hours, the burnt material is allowed to cool to room temperature, the yield of ash remained is in the range of about 1/3"1 of the starting material which is mixed with about 16 to 20 times the volume of distilled water and kept for a week with stirring with the help of wooden ladder every 6 hours, the solution is allowed to stand without any disturbance for maximum 72 hours and the upper supernatant clear liquid is decanted in a suitable capacity, the liquid so obtained is slowly evaporated within the heat range of about 55 to 70°C for 8 to 12 days and clear crystals are obtained.
Example:
100 kg material of Sawana is procured and subjected to our standard procedure of acceptance criteria. After acceptance, the material was quickly washed to remove the surface dust and any other contaminants. The weight was 98.5 kg. It was shade dried in a dust free atmosphere till three constant weights of a random sample of approximate 100 gms. It is crudely pulverized and incinerated in a stainless steel furnace to obtain white ash. The yield is 14.540 kg. The ash is mixed (16 times the weight of material) with 232.64 litrs. of distilled water and stirred vigorously for 1 hour. It is stirred 8 times in a day (every 3 hours) for 7 days.
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The mixture is allowed to stand without any disturbance for 48 hours. The clear supernatant liquid is poured into another stainless steel vessel. The yield is 210.550 litres. This is distributed into 2 stainless steel vessels. All the vessels had a steam jacket for heating. The liquid is heated with slow constant stirring till the crystals are obtained. The yield is 650 gms. The crystals are collected by scraping with a stainless steel spatula and stored in clean glass jars with wide mouth and sealed and stored in cool dry place.
The other variations of the process are given below :
In the absence of electrical energy the solar power shall be used for the further processing of crystallization;
Solar energy shall also be used for aging admixing and precipitation to separate the composition in aqueous phase; this will reduce the air and soil pollution. Minimum chemicals shall be used to avoid contamination of ground water and flora and fauna around, thus preserving the local ecology.
The main advantages are as follows:
1. safe and effective anti-allergic ayurvedic drug
2. minimal or no side effects
3. ease for administration
4. minimum chemical hazards to the employees;
5. it's a cheap and effective, safe anti-allergic composition.
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WE CLAIM:

f. A process for the preparation of a water-soluble crystalline ayurvedic composition
from sawana for the treatment of allergies and histaminergic reactions comprising of collecting 'Sawana' single medicinal plant from jungle areas, the said plant is shed dried till constant weight of the three consecutive samples are identical, this plant is burnt to white ash within a heat range between 280 to 400°C for about 2 to 3 hours, the burnt material is allowed to cool to room temperature, the yield of ash remained is in the range of about 113rd of the starting material which is mixed with about 16 to 20 times the volume of distilled water and kept for a week with stirring with the help of wooden ladder every 6 hours, the solution is allowed to stand without any disturbance for maximum 72 hours and the upper supernatant clear liquid is decanted in a suitable capacity, the liquid so obtained is slowly evaporated within the heat range of about 55 to 70°C for 8 to 12 days and clear crystals are obtained.
2. A process for the preparation of a water-soluble crystalline ayurvedic composition from sawana for the treatment of allergies and histaminergic reactions as claimed in claim 1 and substantially as herein described with reference to an example no.l.

Dated this 18th Day of December, 2000

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(M.D.BHATE) AGENT FOR APPLICANT