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A Process Of Preparation Of Methanamine N [4(3,4 Dichloropheny) 3,4 Dihydro 1(2 H) Naphthalenylidene
Abstract: A process for the preparation of methanamine-N-[4(3,4-dichlorophenyl)]-3,4-dihydro-1(2H)-naphthalenylidene, a critical intermediate in the synthesis of cis-(1S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthylamine hydrochloride generally knwon as sertraline hydrochloride which is an anti-depressant and anorectic agent. Tetralone is condensed with methylamine in the presence of an aliphatic alcohol at 30-60ºC.
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
31 March 1999
Publication Number
11/2007
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
Parent Application
Applicants
SEARLE (INDIA) LIMITED
21 D SUKHADVALA MARG,
MUMBAI 400 021,
Inventors
1. TARUR VENKATASUBRAMANIAN RADHAKRISHNAN
SEARLE (INDIA) LIMITED.,
25 MIDC LAND,
THANE-BELAPUR ROAD,
NEW MUMBAI 400 705
2. SURESH KUMAR NAIR
SEARLE (INDIA) LIMITED.,
25 MIDC LAND,
THANE-BELAPUR ROAD,
NEW MUMBAI 400 705
3. GURUDATT PRABHAKAR DHARESHWAR
SEARLE (INDIA) LIMITED.,
25 MIDC LAND,
THANE-BELAPUR ROAD,
NEW MUMBAI 400 705
4. ANTHONY MELVIN CRASTO
SEARLE (INDIA) LIMITED.,
25 MIDC LAND,
THANE-BELAPUR ROAD,
NEW MUMBAI 400 705
Specification
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 243-bom-1999-abstract(31-3-1999).pdf | 2018-08-08 |
| 1 | 243-bom-1999-form 4(31-3-1999).pdf | 2018-08-08 |
| 2 | 243-bom-1999-claims(31-3-1999).pdf | 2018-08-08 |
| 2 | 243-bom-1999-form 26(31-3-1999).pdf | 2018-08-08 |
| 3 | 243-bom-1999-correspondence(8-11-1999).pdf | 2018-08-08 |
| 3 | 243-bom-1999-form 2(title page)-(31-3-1999).pdf | 2018-08-08 |
| 4 | 243-bom-1999-correspondence(ipo)-(18-2-2011).pdf | 2018-08-08 |
| 4 | 243-bom-1999-form 2(31-3-1999).pdf | 2018-08-08 |
| 5 | 243-bom-1999-form 1(31-3-1999).pdf | 2018-08-08 |
| 5 | 243-bom-1999-description(complete)-(31-3-1999).pdf | 2018-08-08 |
| 6 | 243-bom-1999-description(complete)-(31-3-1999).pdf | 2018-08-08 |
| 6 | 243-bom-1999-form 1(31-3-1999).pdf | 2018-08-08 |
| 7 | 243-bom-1999-correspondence(ipo)-(18-2-2011).pdf | 2018-08-08 |
| 7 | 243-bom-1999-form 2(31-3-1999).pdf | 2018-08-08 |
| 8 | 243-bom-1999-correspondence(8-11-1999).pdf | 2018-08-08 |
| 8 | 243-bom-1999-form 2(title page)-(31-3-1999).pdf | 2018-08-08 |
| 9 | 243-bom-1999-claims(31-3-1999).pdf | 2018-08-08 |
| 9 | 243-bom-1999-form 26(31-3-1999).pdf | 2018-08-08 |
| 10 | 243-bom-1999-form 4(31-3-1999).pdf | 2018-08-08 |
| 10 | 243-bom-1999-abstract(31-3-1999).pdf | 2018-08-08 |