DESC:FORM 2
THE PATENTS ACT 1970
(39 of 1970)
&
The Patents Rules, 2003
COMPLETE SPECIFICATION
(See section 10 and rule 13)
1. TITLE OF THE INVENTION: “A Synergistic Ternary Insecticidal Composition”
2. APPLICANT:
(a) Name : RAJDHANI PETROCHEMICALS PRIVATE LIMITED
(b) Nationality : INDIAN
(c) Address : 6, LALITA COMPLEX, RASALA ROAD, NAVRANGPURA, AHMEDABAD-380009 Gujarat, India
PROVISIONAL
The following specification describes the invention. þCOMPLETE
The following specification particularly describes the invention and the manner in which it is to be performed.

FIELD OF INVENTION
The present invention relates to a synergistic ternary insecticidal composition. More specifically, the present invention relates to a synergistic ternary insecticidal composition comprising N’-tert-butyl-N’-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide, 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-N -[(Z)-methoxyiminomethyl]-2-methylbenzamide, and at least one compound selected from the group of insecticide; and a process of preparing said composition. The present invention further relates to an insecticidal composition that provides an effective control of insect pests and mites, increases plant tolerance against abiotic stress and improves overall health and vigor of the treated plant.

BACKGROUND OF THE INVENTION
In recent years, due to single drug use and unscientific drug use, many pests have become resistant to the currently used insecticides which have become a major problem in chemical control. At the same time, frequent application of insecticides has increased the burden on farmers and increased environmental pollution. Therefore, a new composition of high-efficiency, low-toxicity and environmentally-friendly insecticides has become a mainstream direction in the field of insecticides research. However, insecticides with different action mechanisms can be mixed reasonably according to a certain proportion, which can improve the efficacy against insect pests and mites, reduce the dosage, fewer residues, reduce environmental pollution, and effectively reduce the drug resistance of crops.
The reduction in effectiveness of insecticides due to the development of resistance is one of the forces that drives the discovery and development of new insecticides. Predicting whether or not a resistance mechanism that has conferred resistance to an existing insecticide will confer resistance to a novel insecticide is not necessarily a simple matter.
WO 2023199360A1 patent relates to pesticidal composition comprising bioactive amounts of fluxametamide, one insecticide selected from diamide group, at least one of compound from insecticides, fungicides or plant health additives and exicipients; and process of preparation thereof. The said patent application is concerned with increase plant tolerance against insect pests.
WO2012121121A1 patent relates to pest controlling compound and pest control method. A pest control composition containing: the quinoline compound; at least one hydrazide compound selected from group (A) consisting of chromafenozide, methoxyfenozide, and tebufenozide; and at least one insect/pest control compound selected from group (B) consisting of dinotefuran, ethiprole, thiamethoxam, permethrin, clothianidin, and nitenpyram. Method for controlling pests generally applied to cultivated plants of rice or rice fields.
This above mentioned inventions features binary composition. In contrast, the present invention contains ternary composition which broadens the spectrum of control and improves overall health of plants. The active ingredients known from the literature have certain disadvantages such as insufficient control efficacy, restriction of its use due to the appearance of drug-resistant insects or pests, phytotoxicity and contamination to plants, or toxicity to human beings, beasts, fishes and the like. Hence, there is a long felt need to develop novel and effective insecticidal combinations for controlling the harmful pests in plants that demonstrate high efficacy, are environmentally safe and can be advantageously formulated.
The insecticides currently in use are not that effective; and due to their prolonged indiscriminate and non-judicious use, some pests have developed resistance to such commonly used insecticides. Their use is thereby becoming increasingly difficult.
Therefore, there is an urgent need to develop new compositions, effective methods and formulations for controlling these harmful pests. At last, there is a need to provide an insecticidal composition which overcomes some of the existing problems and can be prepared easily without much complex manufacturing process. The present inventors have surprisingly developed an effective insecticidal combination which ameliorates the aforesaid shortcomings of the prior art.

OBJECT OF THE INVENTION
The principal object of the present invention is to provide a synergistic ternary insecticidal composition.
Another object of the present invention is to provide a synergistic ternary insecticidal composition comprising bioactive amounts of N’-tert-butyl-N’-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide, 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-N-[(Z)-methoxyiminomethyl]-2-methylbenzamide, at least one insecticide and agrochemically acceptable excipients; and method of preparation thereof.
Further object of the present invention is to provide insecticidal composition demonstrating high efficacy.
Yet another object of the present invention is to provide insecticidal composition for controlling the harmful pests in plants and to provide complete protection to crop plants against insect-pests and mites.
Still another object of the present invention is to provide insecticidal composition increasing plant tolerance against abiotic stress.
Further object of the present invention is to provide insecticidal composition to delay resistance development through engaging multiple modes of action or for insect pests and mite resistance management.
Another object of the present invention is to provide a method of preparing a stable and non-phytotoxic formulation which improves overall health, yield and vigor of the treated plant.
Further object of the present invention is to provide insecticidal composition which is environmentally safe.

SUMMARY OF THE INVENTION
The present invention provides a synergistic ternary insecticidal composition. More particularly comprising bioactive amounts of (A) N’-tert-butyl-N’-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide (B) 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-N-[(Z) -methoxyiminomethyl]-2-methylbenzamide; (C) at least one compound selected from the group of insecticides; and agrochemically acceptable excipients.
The formulation for an insecticidal composition is selected from Capsule suspension (CS), Dispersible concentrate (DC), Emulsifiable concentrate (EC), Emulsion, water in oil (EO), Emulsion, oil in water (EW), Micro-emulsion (ME), Oil dispersion (OD), Oil miscible flowable concentrate (oil miscible suspension (OF), Oil miscible liquid (OL), Suspension concentrate (SC), Suspo-emulsion (SE), Soluble concentrate (SL), Water dispersible granule (WG or WDG), Water soluble granule (SG), Water soluble powder (SP), Wettable powder (WP), A mixed formulation of CS and SC (ZC), A mixed formulation of CS and SE (ZE), a mixed formulation of CS and EW (ZW), Granule (GR) for soil application includes controlled release granules (CR), Jambo balls or bags (bags in water soluble pouch).
The process for preparing the present insecticidal composition can be modified accordingly by any person skilled in the art based on the knowledge of the manufacturing the formulation. However, all such variation and modification is still covered by the scope of present invention.
The present invention is formulated to control harmful insect pests and mites in plants demonstrating high efficacy and providing resistance management or to delay resistance development through engaging multiple modes of action. Further, the insecticidal composition is effective on crops which have been rendered tolerant to herbicides or class of herbicides. Moreover, it also showcases its synergistic efficacy on the crops rendering resistant towards harmful insects by genetic engineering methods. Therefore, the insecticidal composition results in an increase in plant tolerance against insect-pests and mites, abiotic stress and improve overall health and vigor of the treated plant making it environment friendly and demonstrating high efficacy.
DETAILED DESCRIPTION OF THE INVENTION
Before explaining the present invention in detail, it is to be understood that the invention is not limited in its application to the details of the parts illustrated. The invention is capable of other embodiments, as described above and of being practiced or carried out in a variety of ways. It is to be understood that the phraseology and terminology employed herein is for the purpose of description and not to limitation. The invention may have various embodiments and they may be performed as described in the following pages of the complete specification.
The terms and words used in the following description are not limited to the bibliographical meanings, but, are merely used by the inventors to enable a clear and consistent understanding of the invention. Accordingly, it should be apparent to those skilled in the art that the following description of exemplary embodiments of the present invention are provided for illustration purpose only and not for the purpose of limiting the scope of the invention.
It is to be understood that the singular forms "a," "an," and "the" include plural reference unless the context clearly dictates otherwise.
Features that are described and/or illustrated with respect to one embodiment may be used in the same way or in a similar way in one or more other embodiments and/or in combination with or instead of the features of the other embodiments.
It should be emphasized that the term "comprises/comprising" when used in this specification is taken to specify the presence of stated features, steps or components but does not preclude the presence or addition of one or more other features, steps, components or groups thereof.
The term 'plants' as used herein, refers to all physical parts of a plant, including seeds, seedlings, saplings, roots, tubers, stems, stalks, foliage and fruits. The term "plant" is to be understood as including wild type plants and plants, which have been modified by either conventional breeding, or mutagenesis or genetic engineering, or by a combination thereof.
The term "crop" refers to both, growing and harvested crops.
The term "insects" as used herein, includes all organisms in the class "Insecta."
The term "animal pest" includes arthropods, gastropods, and nematodes. Preferred animal pests according to the invention are arthropods, preferably insects and arachnids, in particular insects. Insects, which are of particular relevance for crops, are typically referred to as crop insect pests.
The term "insecticidal" as used herein, refers to the ability of an insecticide to increase mortality or inhibit growth rate of insects.
To "control" or "controlling" pests means to inhibit, through a toxic effect, the ability of pests to survive, grow, feed, and/or reproduce, or to limit pest related damage or loss in crop plants. To "control" pests may or may not mean killing the pests, although it preferably means killing the pests.
The term "health of a plant" or "plant health" is defined as a condition of the plant and/or its products. As a result of the improved health, yield, plant vigor, quality and tolerance to abiotic or biotic stress are increased.
"Yield" is to be understood as any plant product of economic value that is produced by the plant such as grains, fruits in the proper sense, vegetables, nuts, grains, seeds, wood (e.g. in the case of silviculture plants) or even flowers (e.g. in the case of gardening plants, ornamentals).
"Increased yield" of a plant, in particular of an agricultural, silvicultural and/or horticultural plant means that the yield of a product of the respective plant is increased by a measurable amount over the yield of the same product of the plant produced under the same conditions, but without the application of the composition according to the invention.
The present invention provides an insecticidal composition comprising
1. Compound A - N’-tert-butyl-N’-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide,
2. Compound B - 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-N-[(Z)-methoxyiminomethyl]-2-methylbenzamide,
3. Compound C - at least one compound selected from group of insecticides with the following mass percentage of the composition.
Sr. No. Ingredient Concentration range (w/w %)
1. Compound A 10 to 50
2. Compound B 1 to 20
3. Compound C 1 to 30
Compound A is methoxyfenozide, N’-tert-butyl-N’-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide is a benzoyl hydrazine low-toxic insecticide with high selective insecticidal activity against lepidopteran pests.

Compound A is mainly focused on contact-killing and has a certain systemic action, strong selectivity and has good control effect on lepidopteran pests such as cotton bollworm, cabbage caterpillar and diamondback moth, and is suitable for controlling human, animal and environmental safety, and is suitable for controlling vegetables, tea trees, fruit trees, ornamental plants and rice.
Compound B is fluxametamide, 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-N -[(Z)-methoxyiminomethyl]-2-methylbenzamide is a novel wide-spectrum insecticide that was discovered and synthesized by Nissan Chemical Industries, Ltd. It belongs to a class of compounds called isoxazolines, which are potent inhibitors of ?-aminobutyric acid (GABA)-, glutamate-, and glycine-gated chloride channels in insects.

Compound C is a wide-spectrum insecticide effective against a broad spectrum of pests. It is mainly used in the control of lepidopteran pests, thrips, whiteflies, leaf miners, beetles and mites on crops such as fruit trees, vegetables, soybeans, cotton and tea trees and other crops.
Insecticide(s) for Compound C is selected from but not limited to,

from the class of organophosphates (AChE-acetylcholine esterase inhibitors),

from the class of phenylpyrazoles-fiproles (GABA-gated chloride channel blockers) ,

from the class of pyrethroids (sodium channel modulators),

from the class of nicotinic insecticides (nicotinic acetylcholine receptor (nAChR) competitive modulators),

from the class of nereis toxin analogues (nicotinic acetylcholine receptor (nAChR) channel blockers),

from the class of spinosyns (nicotinic acetylcholine receptor (nAChR) allosteric modulators-Site I) ,

from the class of avermectins and milbemycins (glutamate-gated chloride channel (GluCl) allosteric modulators),

from the class of juvenile hormone mimics,

from the class of chordotonal organs modulators,

from the class of mite growth inhibitors affecting CHS1,

from the class of benzoylureas (inhibitors of the chitin biosynthesis affecting CHS1 ,

from the class of buprofezin (inhibitors of the chitin biosynthesis type 1),
from the class of cyromazine (moulting disruptors for dipteran),

from the class of microbial disruptors of insect midgut membrane,

from the class of uncouplers of oxidative phosphorylation,

from the class of octopamin receptor agonists: amitraz; from the class of inhibitors of mitochondrial ATP synthase,

from the class of METI (mitochondrial complex I) inhibitors,

from the class of METI (mitochondrial complex II) inhibitors,

from the class of METI (mitochondrial complex III) inhibitors,

from the class of METI (mitochondrial complex IV) inhibitors,

from the class of voltage-dependent sodium channel blockers,

from the class of inhibitors of the lipid synthesis, inhibitors of acetyl CoA carboxylase,

from the class of baculoviruses,

from the class of calcium activated potassium channel (KCa2) modulators and compounds of unknown or uncertain mode of action.

Compound C is selected from group consisting of

C1 acetamiprid, N-[(6-chloropyridin-3-ylmethyl-N’-cyano-N-methylemethanimidamide,

C2 clothianidin, 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3-methyl-2-nitroguanidine,
C3 bifenthrin, (2-methyl-3-phenylphenyl)methyl (1R,3R)-3-[(Z)-2-chloro-3,3,3-trifluoroprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate,

C4 lambda cyhalothrin, [(R)-cyano-(3-phenoxyphenyl)methyl] (1S,3S)-3-[(Z)-2-chloro-3,3,3-trifluoroprop-1-enyl]-2,2-dimethylcyclopropane-1 -carboxylate,

C5 acephate, N-[methoxy (methylsulfanyl)phosphoryl]acetamide,

C6 profenofos, 4-bromo-2-chloro-1-[ethoxy(propylsulfanyl)phosphoryl]oxybenzene,

C7 thiocyclam hydrogen oxalate, N,N-dimethyltrithian-5-amine;oxalic acid,

C8 cartap hydrochloride, S-[3-carbamoylsulfanyl-2-(dimethylamino)propyl] carbamothioate,

C9 spinosad, mixture of 50–95% (2R,3aS,5aR,5bS,9S,13S,14R,16aS,16bR)-2-[(6-deoxy-2,3,4-tri-O-methyl-a-L -mannopyranosyl)oxy]-13-{[4-(dimethylamino)-2,3,4,6-tetradeoxy-ß- D erythropyranosyl]oxy}-9- ethyl-2,3,3a,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b hexadecahydro-14-methyl-1H-as-indaceno[3,2-d]oxacyclododecine-7,15 dione and 50–5% (2S,3aR,5aS,5bS,9S,13S,14R,16aS,16bS)-2-[(6-deoxy-2,3,4-tri-O-methyl-a-L-mannopyranosyl)oxy]-13-{[4-(dimethylamino)-2,3,4,6 tetradeoxy-ß-D-erythropyranosyl]oxy}-9-ethyl 2,3,3a,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-hexadecahydro-4,14-dimethyl-1H-as-indaceno[3,2-d]oxacyclododecine-7,15 –dione,

C10 spinetoram, (2R,5R,9R,10S,14R,15S,19S)-15-[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy-7-[(2R,3R,4R,5S,6S)-4-ethoxy-3,5 -dimethoxy-6-methyloxan-2-yl]oxy-19-ethyl-14-methyl-20 oxatetracyclo [10.10.0.0.0]docos-11-ene-13,21-dione,
C11 emamectin benzoate, (1'R,2R,3S,4'S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-2-[(2S)-butan-2 -yl]-21',24'-dihydroxy-12'-[(2R,4S,5S,6S)-4-methoxy-5-[(2S,4S,5S,6S)-4 -methoxy-6-methyl-5-(methylamino)oxan-2-yl]oxy-6-methyloxan-2-yl]oxy -3,11',13',22'-tetramethylspiro[2,3-dihydropyran-6,6'-3,7,19 -trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2'-one,

C12 novaluron, N-[[3-chloro-4-[1,1,2-trifluoro-2-(trifluoromethoxy)ethoxy]phenyl]carbamoyl]-2,6-difluorobenzamide,

C13 abamectin, 1'R,2R,3S,4'S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-2-butan-2-yl-21',24'-dihydroxy-12'-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-3,11',13',22' -tetramethylspiro[2,3-dihydropyran- 6,6'-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2' -one;(1'R,2R,3S,4'S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-21',24' -dihydroxy-12'-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6 -methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-3,11',13',22' -tetramethyl-2-propan-2-ylspiro[2,3-dihydropyran-6,6'-3,7,19 -trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2'-one,

C14 hexythiazox, (4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide,

C15 fenpyroximate, tert-butyl 4-[[(E)-(1,3-dimethyl-5 phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate,

C16 diafenthiuruon, 1-tert-butyl-3-[4-phenoxy-2,6-di(propan-2-yl)phenyl]thiourea,

C17 pyriproxyfen, 2-[1-(4-phenoxyphenoxy) propan-2-yloxy] pyridine and

C18 flonicamid, N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide.

The present invention optionally comprises agrochemically acceptable excipients including, but not limited to, dispersing agents, anti-freezing agent, anti-foam agent, wetting agents, suspension aid and carriers, anti-microbial agent, thickener, colorants, quick coating agent or sticking agents (also referred to as “stickers” or “binders”), polymers, disintegrating agent, oil additive, buffering agent, and solvents.
However, those skilled in the art will appreciate that it is possible to utilize additional agrochemically acceptable excipients without departing from the scope of the present invention. The agrochemically acceptable excipient can be in the range from 0.1% to 99% of the total weight of the composition.
The amount of a composition according to the invention to be applied, will depend on various factors, such as the subject of the treatment, such as, for example plants, soil or seeds; the type of treatment, such as, for example spraying, dusting or seed dressing; the purpose of the treatment, such as, for example prophylactic or therapeutic disease control; in case of disease control the type of fungi to be controlled or the application time. This amount of the combinations of the present invention to be applied can be readily deduced by a skilled agronomist.
The combination of the present invention is formulated in a manner which suits the specific application. The formulation is selected from Capsule suspension (CS), Dispersible concentrate (DC), Emulsifiable concentrate (EC), Emulsion, water in oil (EO), Emulsion, oil in water (EW), Micro-emulsion (ME), Oil dispersion (OD), Oil miscible flowable concentrate (oil miscible suspension (OF), Oil miscible liquid (OL), Suspension concentrate (SC), Suspo-emulsion (SE), Soluble concentrate (SL), Water dispersible granule (WG or WDG), Water soluble granule (SG), Water soluble powder (SP), Wettable powder (WP), A mixed formulation of CS and SC (ZC), A mixed formulation of CS and SE (ZE), a mixed formulation of CS and EW (ZW), Granule (GR) for soil application includes controlled release granules (CR), Jambo balls or bags (bags in water soluble pouch).
More particularly, the composition is selected from Oil dispersion (OD), Suspo Emulsion (SE), Suspension Concentrate (SC), Suspo-emulsion (SE), Water Dispersible Granule/ Wettable Granule (WG/WDG), Wettable powder (WP) and a mixed formulation of capsule suspension CS and SC (ZC).
The inactive excipients used in various formulations are as follows:

A. Lists of inactive excipients used in Oil dispersion (OD) formulation:

The Oil Dispersion formulation (OD) of the present invention comprises agrochemically acceptable excipients including, but not limited to, wetting agent(s), wetting-spreading-penetrating agent(s), emulsifying agent(s), dispersing agent(s), stabilizer(s), antifoaming agent(s), antifreezing agent(s), solvent(s), and rheology modifier.

The wetting agent of OD is selected from, but not limited to, ethylene oxide/propylene oxide block copolymer, polyarylphenyl ether phosphate, ethoxylated fatty alcohol, sodium dioctyl sulfosuccinate, sodium lauryl sulphate, sodium dodecyl benzene sulfonate, alkyldiphenyl sulfonates, sodium isopropyl naphthalene sulfonate, alkylnaphthalenesulfonate or mixture thereof.

The wetting-spreading-penetrating agent of OD is selected from, but not limited to, organosilicone surfactants, trisiloxane ethoxylate, polydimethylsiloxane, polyoxyethylene methyl polysiloxane, polyoxyalkylene methyl polysiloxane, polyether polymethyl siloxane copolymer, heptamethyl trisiloxane, polyalkyleneoxide modified heptamethyl trisiloxane, polyether modified polysiloxane, may or may not be in modified form, may be liquid or powder form or mixture thereof.

The emulsifying agent of OD is selected from, but not limited to, castor oil ethoxylates, alcohol ethoxylates, fatty acid ethoxylates, sorbitan ester ethoxylates, sulphosuccinate, calcium salts of dodecylbenzene sulphonate, alkylammonium salts of alkylbenzene sulphonate, alkylsulphosuccinate salts, ethylene oxide-propylene oxide block copolymers, ethoxylated alkylamines, ethoxylated alkyl phenols, polyoxyethylene sorbitan monolaurate, polyxyethylene sobitol hexaoleate, ethoxylated sorbiton ester or mixture thereof.

The dispersing agent of OD is selected from, but not limited to, alkyl sulfonates, alkyl benzene sulfonates, alkyl aryl sulfonates, alkylphenolalkoxylates, tristyrylphenol ethoxylates, natural or synthetic fatty ethoxylate alcohols, natural or synthetic fatty acid alkoxylates, natural or synthetic fatty alcohols alkoxylates, alkoxylated alcohols such as n-butyl alcohol poly glycol ether, block copolymers such as ethylene oxide-propylene oxide block copolymers, ethylene oxide-butylene oxide block copolymers, fatty acid-polyalkylene glycol condensates, polyamine-fatty acid condensates, polyester condensates, salts of polyolefin condensates, sodium ligno sulfonate, sodium ploycarboxylate, EO/PO based copolymer, phenol sulfonate, sodium methyl oleoyl taurate, styrene acrylic acid copolymer, propyleneoxide-ethyleneoxide-copolymer, polyethylene glycol 2,4,6-tristyrylphenyl ether, tristyrylphenol-polyglycolether-phosphate, tristyrylphenole with 16 moles EO, tristyrylphenol-polyglycolether-phosphate, oleyl-polyglycolether with ethylene oxide, tallow fattyamine polyethylene oxide, nonylphenol polyglycolether with 9-10 moles ethylene oxide, salts of polyolefin condensates, styrene acrylic polymer or mixture thereof.

The stabilizers of OD is selected from, but not limited to, hectorite clay, aluminium magnesium silicate, bentonite clay, silica, attapulgite clay or mixture thereof.

The antifoaming agent of OD is selected from, but not limited to,silicone oil, silicone compound, C10~C20 saturated fat acid compounds, C8~C10 aliphatic alcohols compound, silicone antifoam emulsion, dimethylsiloxane, polydimethyl siloxane, vegetable oil based antifoam, tallow based fatty acids, polyalkyleneoxide modified polydimethylsiloxane or mixture thereof.

The anti-freezing agent of OD is selected from, but not limited to, ethylene glycol, propane diols, glycerine, the urea, glycol monoethylene glycol, diethylene glycol, polypropylene glycol, polyethylene glycol, glycerine, urea, magnesium sulfate heptahydrate, sodium chloride, preservative-1,2-benzisothiazolin-3(2H)-one, sodium salt, sodium benzoate, 2-bromo-2-nitropropane-1,3-diol, formaldehyde, sodium o-phenylphenate, 5-chloro-2-methyl-4-isothiazolin-3-one, 2-methyl-4-isothiazolin-3-one or mixture thereof.

The solvent of OD is selected from, but not limited to, vegetable oil its alkylated orethoxylated or esterified form, the alkylated vegetable oil, methylated vegetable oil, ethylated vegetable oil, the vegetable oils include olive oil, kapok oil, castor oil, papaya oil, camellia oil, sesame oil, corn oil, rice bran oil, cotton seed oil, soybean oil, groundnut oil, rapeseed-mustard oil, linseed oil, tung oil, sunflower oil, safflower oil, coconut oil, the alkyl ester of vegetable oils, methyl ester, ethyl ester, propyl ester, butyl ester of vegetable oils, methylated seed oil, polyalkyleneoxide modified polydimethylsiloxane alkylphenol ethoxylate, rapeseed oil methyl ester, rapeseed oil ethyl ester, rapeseed oil propyl esters, rapeseed oil butyl esters, soybean oil methyl ester, soybean oil ethyl ester, soybean oil propyl ester, soybean oil butyl ester, castor oil methyl ester, castor oil ethyl ester, castor oil propyl ester, castor oil butyl ester, cotton seed oil methyl ester, cotton seed oil ethyl ester, cotton seed oil butyl ester, cotton seed oil propyl ester, tall oil fatty acids esters-tallow methyl ester, tallow ethyl ester, tallow propyl ester, bio-diesel, mineral oil, aromatic solvents, isoparaffin, base solvent, fatty acid amides, C1-C3 amines, alkylamines, alkanolamines with C6-C18 carboxylic acids, fatty acids, alkyl esters of fatty acids, methyl oleate, ethyl oleate, methyl soyate, ethyl soyate, alkyl benzenes, alkylnaphthalenes, polyalkylene glycol ethers, fatty acid diesters, fatty alkylamides, diamides, dialkylene carbonates, ketones, alcohols, cyclohexanone, acetophenone, NMP, dimethyl sulfoxide, benzyl alcohol, butanol, N-octanol, N-propanol, 2-ethyl hexanol, tetrahydro furfuryl alcohol, isophorone, fatty acid dimethyl amide, 2-hexylethyl lactate, propylene carbonate, methylated seed oil or mixture thereof.

The rheology modifier of OD is selected from, but not limited to bentonite clay.

Manufacturing process for Oil dispersion (OD) formulation:

Part A-Preparation of the liquid premix (OD)
Step 1: The vegetable oil or solvent or both are charged into a vessel with an anchor stirrer.
Step 2: The emulsifier(s) and dispersing agent(s) are added under stirring condition until all the ingredients get completely dissolved.

Part B-Preparation of the slurry (OD)
Step 1: The liquid premix is charged into a second vessel which is equipped with a cooling and heating device of a high shear stirrer.
Step 2: The active ingredients are added and homogenized thoroughly. The mixture is pre-milled and a particle size distribution is achieved by the final milling, practised along with a bead mill as required by the specification.

Part C-Preparation of the thickener gel (OD)
Step 1: The vegetable/plant/seed oil or solvent is charged to the vessel which is equipped with a high shear stirrer.
Step 2: The thickener(s) is/are gradually added throughout by mixing and maintaining high-shear. The stirring is continued until thoroughly mixed.
Step 3: The thickener activating agent(s) is/are added under stirring condition. Further, the gel is allowed to get swell whilst maintaining the mixing.

Part D-Preparation of the final formulation (OD)
Step 1: The thickener gel is added and the mixture is dispersed by using a high shear stirrer.
Step 2: The recommended wetting and spreading agent(s) or adjuvant(s) (silicone or non-silicone based) are finally added to this formulation and dispersed by using high shear stirrer.
Step 3: The finished formulation is checked with specification.
Step 4: The material is packed in its required package sizes when approved.

B. Lists of inactive excipients used in Suspension Concentrate (SC) formulation:

The Suspension Concentrate formulation (SC) of the present invention comprises agrochemically acceptable excipients including, but not limited to, wetting agent(s), wetting-spreading-penetrating agent(s), dispersing agent(s), suspending agent(s), antifoaming agent(s), antifreezing agent(s), preservative(s), thickener(s) and humectants(s).

The wetting agent of SC is selected from, but not limited to, ethylene oxide/propylene oxide (EO/PO) block copolymer, polyarylphenyl ether phosphate, polyalkoxylated butyl ether, ethoxylated fatty alcohol, sodium dioctyl sulfosuccinate, sodium lauryl sulfate, sodium dodecyl benzene sulfonate, alkyl diphenyl sulfonates, sodium isopropyl naphthalene sulfonate, alkyl naphthalene sulfonate, ethoxylated alcohol, natural fatty alcohol, lauryl alcohol ethoxylate, lauryl alcohol alkoxylate, synthetic alcohol ethoxylate, tridecyl alcohol ethoxylate, 2-ethyl hexanol, 2-propylheptanol, isodecyl alcohol or mixture thereof.

The wetting-spreading-penetrating agent of SC is selected from, but not limited to, methylated seed oil, polyakyleneoxide modified trisiloxane, trisiloxane ethoxylate, heptamethyl trisiloxane, modified polyalkyleneoxide, modified heptamethyl trisiloxane, polyether modified polysiloxane, polyalkyleneoxide modified trisiloxane, polyalkyleneoxide modified polydimethylsiloxane, liquid or powder form or mixture thereof.

The dispersing agent of SC is selected from, but not limited to, ethylene-propylene oxide block coplolymer, naphthalenesulfonic acid, sodium salt condensate with formaldehyde, alkylated naphthalene sulfonate, sodium salt, sodium salt of naphthalene sulfonate condensate, sodium ligno sulfonate, sodium polycarboxylate, EO/PO based copolymer, phenol sulfonate, sodium methyl oleoyl taurate, styrene acrylic acid copolymer, propylene oxide-ethylene oxide-copolymer, polyethylene glycol 2,4,6-tristyrylphenyl ether, tristyrylphenol-polyglycol ether-phosphate, tristyrylphenole with 16 moles EO, tristyrylphenol-polyglycol ether-phosphate, oleyl-polyglycol ether with ethylene oxide, tallow fatty amine polyethylene oxide, nonylphenol polyglycol ether with 9-10 moles ethylene oxide, sodium naphthalene sulphonate formaldehyde condensates or mixture thereof.

The suspending agent of SC is selected from, but not limited to, aluminum magnesium silicate, bentonite clay, silica, attapulgite clay or mixture thereof.

The antifoaming agent of SC is selected from, but not limited to, silicone antifoam emulsion, dimethyl siloxane, polydimethylsiloxane, vegetable oil based antifoam, tallow based fatty acids or mixture thereof.

The anti-freezing agent of SC is selected from ethylene glycol, propane diols, glycerin or the urea, glycol, monoethylene glycol, diethylene glycol, polypropylene glycol, polyethylene glycol, glycerin, urea, magnesium sulfate heptahydrate, sodium chloride or mixture thereof.

The preservatives of SC is selected from, but not limited to, 1,2-benzisothiazolin-3(2H)-one, sodium salt, sodium benzoate, 2-bromo-2-nitropropane-1,3-diol, formaldehyde, sodium o-phenyl phenate, 5-chloro-2-methyl-4-isothiazolin-3-one, 2-methyl-4-isothiazolin-3-one or mixture thereof.

The thickeners of SC is selected from, but not limited to, xanthan gum, PVK, carboxymethyl celluloses, polyvinyl alcohols, gelatin, sodium carboxymethylcellulose, hydroxyethyl cellulose, sodium polyacrylate, modified starch, acacia gum or mixture thereof.

The humectants of SC is selected from, but not limited to, urea, humic acid, glycerol, lactose or mixture thereof.

Manufacturing process for Suspension Concentrate (SC) formulation:

Step 1: Gel preparation: A required quantity of water is charged to a vessel which is equipped with a high shear stirrer whilst the agitation is initiated. A required amount of preservative(s) is/are added and mixed to form a homogenous mixture. A required amount of thickener(s) is/are added and mixed vigorously to achieve wetness.

Step 2: A required quantity of water is charged to a vessel which is equipped with a bulk agitator and a high shear homogenizer; initiated the agitation. Further, a required amount of an anti freezing agent(s) is/are added and mixed to achieve uniformity. Moreover, the antifoaming agent(s) is/are added whilst ensuring that it is well dispersed. The wetting and dispersing agent(s) is/are added and mixed to achieve uniformity whilst ensuring that the dispersing agent(s) is/are fully dispersed.

Step 3: The active ingredients are added and the agitation of the vessel contents are continued until all the compounds get dissolved. The pre-mix is milled through a colloid mill and subsequently through a dyno mill to meet the specified particle size.

Step 4: The remaining antifoaming agent(s) is/are added to this SC mill base to a vessel which is equipped with the bulk agitator and mixed to achieve uniformity. The required amount of 2% aqueous pre-gel and suspending agent(s) is/are added and the agitation is continued until the formulation is homogeneous and has reached the target viscosity.

Step 5: The final product is submitted for QC’s approval.

Step 6: The material is packed in its required package sizes when received approval.

C. Lists of inactive excipient used in Suspo Emulsion (SE) formulation [mixed formulation of SC+EC]:

The Suspo Emulsion formulation (SE) is a mixture of Suspension Concentrates (SC) and Emulsifiable Concentrate (EC). The Suspo Emulsion
(SE) of the present invention comprises agrochemically acceptable excipients including, but not limited to, solvent(s), emulsifier(s), stabilizer(s), antifreezing agent(s), antifoaming agent(s), suspending agent(s), wetting agent(s), wetting-spreading-penetrating agent(s), preservative(s), thickener(s), dispersing agent(s), buffering agent(s) and humectants(s). Since the excipients for SC are the same, only the excipients for SE are listed here.

The solvent of SE is selected from, but not limited to, water, water soluble alcohols and dihydroxy alcohol ethers, water soluble alcohol or lower alcohol -1 to 4 carbon atoms, methanol, ethanol, n-propanol, isopropanol, n-butanol, tert-butanol, macromolecular alcohol, polyethylene glycol, sorbitol, glucitol, dihydroxy alcohol ethers, dihydroxy alcohol alkyl ether, dihydroxy alcohol aryl ethers, dihydroxy alcohol alkyl ether, ethylene glycol methyl ether, diethylene glycol methyl ether, propylene glycol methyl ether, di-propylene glycol methyl ether, ethylene glycol ethyl ether, diethylene glycol ethyl ether, propylene glycol ethyl ether, di-propylene glycol ethyl ether, dihydroxy alcohol aryl ethers includes ethylene glycol phenyl ether, diethylene glycol phenyl ether, propylene glycol phenyl ether, di-propylene glycolphenyl ether, aromatic solvent C-9 or in combination thereof.
Hyrdocarbons, n-pentane, hexane(s), cyclohexane, methylcyclohexane, heptane, isooctane, benzene, toluene, xylene(s), isophorone, ester solvents, methyloleate, dimethylamide, morpholineamide derivatives of C6-C16 fatty acids, mono-alkylene carbonates, ethylene carbonate, propylene carbonate, butylene carbonates, dimethylsulfoxide (DMSO), 2-ethylhexanol, n-butanol, n-alkylpyrrolidones, fatty acid dimethyl esters, fatty acid esters, dibasic esters, aromatic hydrocarbons, aliphatic hydrocarbons, one or more dimethylamides, C8-dimethylamide, C10-dimethylamide, C12-dimethylamide, ethylene glycol, propylene glycol, polyalkylene glycols, aromatic hydrocarbons, methylpyrrolidinone (NMP), dimethylformamide (DMF), dimethylisosorbide (DMI), isophorone, acetophenone, 1,3-dimethyl-2-imidazolidonone, lactate esters, dimethyl, diethylcarbonates, alcohols including methanol, ethanol, iso-propanol, n-propanol, n-butanol, iso-butanol, tert-butanol, methyl L-lactate, 2-ethylhexyl L-lactate, ethyl L-lactate, n-butyl L-lactate, octyl phenol ethoxylates or mixture thereof.

The emulsifier of SE is selected from, but not limited to, salts of dodecylbenzene sulphonate, Ca-salts, amine salts, sulphonates of other C11-C16 alkylbenzenes, alkylether sulphates, alkylphenoletherphosphates, ester phosphates, non-ionic surfactants, alkoxylated alcohols, alkylphenols, ethoxylated fatty acids, ethoxylated vegetable oils, ethoxylated castor oil, fatty acid esters, sorbitol, their ethoxylated derivatives, ethoxylated amines, condensates of glycerol, catanionic emulsifiers, cationic amine, alkylsulphonate, ether sulphonate, ether phosphate, alkoxylated alcohols, alkoxylated alkylphenols, ethoxylated fatty acids, ethoxylated vegetable oils, ethoxylated tristyrylphenol-tristyrlphenol with 16 moles EO, tristyrylphenol-polyglycolether-phosphate, fatty acid esters of sorbitol, ethoxylated derivatives thereof, ethoxylated amines, condensates of glycerol, sulfonated alkylbenzenes in the range C11-C16, salts thereof, alkylether sulphates, alkyletherphosphates, alkylphenoletherphosphates, salts of phosphate esters of ethoxylated tristyrylphenol, salts of sulphated ethers of ethoxylated tristyrylphenol, catanionic system, alkylsulphonate, alkylethersulphonate, ether sulphate, ether phosphate, alkyletherphosphate, nonylphenol polyethoxyethanols, castor oil polyglycol ethers, poly adducts of ethylene oxide and polypropylene, tributyl phenoxy polyethoxy ethanol, octyl phenoxy polyethoxy ethano, polyarylphenyl anionic ether sulphate, ammonium salts or mixture thereof.

The stabilizer of SE is selected from, but not limited to, butylated hydroxytoluene (BHT) and epoxidized soybean oil (ESBO), epichlorhydrin or mixture thereof.

The buffering agent of SE is selected from, but not limited to, calcium hydroxyapatite, potassium dihydrogen phosphate, sodium hydroxide, carbonated apatite, calcium carbonate, sodium bicarbonate, tricalcium phosphate, calcium phosphates, carbonated calcium phosphates, amine monomers, lactate dehydrogenase, magnesium hydroxide, citric acid or mixture thereof.

Manufacturing process for Suspo Emulsion (SE) formulation:

Step 1: Gel preparation: A required quantity of water is charged to a vessel which is equipped with a high shear stirrer whilst the agitation is initiated. The required amount of preservative(s) is/are added and mixed to achieve homogeneity. Further, a required amount of thickener(s) is/are added and mixed vigorously to achieve full wetness.

Step 2: Oil phase: The solvent(s) is/are charged into the vessel and then the active is slowly added and if required, it is heated for 50°C so that the active ingredients can be dissolved in the solvent and followed by addition of emulsifier(s).

Step 3: The agitation is initiated when a required quantity of water is charged to a vessel which is equipped with a bulk agitator and a high shear homogenizer. A required amount of anti freezing agent(s) is/are added and mixed to achieve a uniform mixture. The antifoaming agent(s) is/are added and ensured that it is well dispersed. The wetting and dispersing agent(s) is/are added and mixed to achieve uniform mixture and ensured that the dispersing agent is fully dispersed.

Step 4: The active ingredients are added in the vessel and agitated till entire compounds get dissolved. The pre-mix is milled through a colloid mill and subsequently through a dyno mill to achieve a specified particle size.

Step 5: The remaining antifoaming agent(s) is/are added in the mill base to a vessel which is equipped with bulk agitator and mixed to achieve uniformity.

Step 6: An addition of an oil phase in an aqueous phase is performed and stirred for 30 minutes by using homogenizer.

Step 7: A required amount of aqueous pre-gel and suspending agent(s) are added. A homogenous mixture and a target viscosity are achieved by continuous agitation.

Step 8: The final product is submitted for QC’s approval.

Step 9: The material is packed in its required package sizes when approved.

D. Lists of inactive excipient used in WG (Wettable Granule)/WDG (Water Dispersible Granule) formulation:

The wettable granule/ water dispersible granule formulation (WG/WDG) of the present invention comprises agrochemically acceptable excipients including, but not limited to, dispersing agent(s), wetting agent(s), antifoaming agent(s), carrier(s), disintegrating agent(s) and humectants(s).

The dispersing agents of WG/WDG is selected from, but not limited to, alkylnaphthalene sulfonate sodium salt, alkylnaphthalene sulfonate, modified polyacrylate copolymer, sodium polycarboxylate, naphthalenesulfonic acid, sodium salt condensates with formaldehyde, polyalcoxylated alkylphenol, naphthalenesulfonic acid formaldehyde condensate, methylnaphthalene-formaldehyde-condensate sodium salt, naphthalene condensates, lignosulfonates, polyacrylates, phosphate esters, calcium lignosulfonate, lignin sulfonate sodium salt or mixture thereof.

The wetting agents of WG/WDG is selected from, but not limited to, sodium N-methyl-N-oleoyl taurate, alkylated naphthalene sulfonate, sodium salt, mixture of isomers of dibutylnaphthalene sulphonic acid sodium salt, sodium di-isopropylnaphthalenesulphonate, sodium isopropyl naphthalene sulphonate, sodium lauryl sulfate, dioctyl sulfate, alkyl naphthalene sulfonates, phosphate esters, sulphosuccinates, non-ionic, tridecyl alcohol ethoxylate, alkyl-alkaryl sulfonates such as alkylbenzene sulfonates, alpha olefin sulfonate, alkyl naphthalene sulfonates, ethoxylated, non-ethoxylated alkyl, alkaryl carboxylates, alkyl, alkaryl phosphate esters, alkyl polysaccharide, di, mono alkyl sulfosuccinate derivatives, alpha olefin sulfonates, alkyl naphthalene sulfonates, dialkyl sulphosuccinates, butyl, dibutyl, isopropyl, di-isopropyl naphthalene sulfonate salts, C12 alkyl benzene sulfonate or C10-C16 alkyl benzene sulfonate, organosilicons surfactants includes trisiloxane ethoxylate, polydimethylsiloxane, polyoxyethylene methyl polysiloxane, polyoxyalkylene methyl polysiloxane, polyether polymethyl siloxane copolymer, trisiloxaneheptamethyl, polyalkyleneoxide modified heptamethyl trisiloxane, polyether modified polysiloxane or mixture thereof.

The antifoaming agent of WG/WDG is selected from, but not limited to polydimethylsiloxane.

The carrier of WG/WDG is selected from, but not limited to, china clay, silica, lactose anhydrous, ammonium sulfate, sodium sulfate anhydrous, corn starch, urea, EDTA, urea formaldehyde resin, diatomaceous earth, kaolin, bentonite, kieselguhr, fuller's earth, attapulgite clay, bole, loess, talc, chalk, dolomite, limestone, lime, calcium carbonate, powdered magnesia, magnesium oxide, magnesium sulphate, sodium chloride, gypsum, calcium sulphate, pyrophyllite, silicates, silica gels, fertilizers, ammonium sulphate, ammonium phosphate, ammonium nitrate and urea, natural products of vegetable, grain meals, flours, bark meals, wood meals, nutshell meals, cellulosic powders, synthetic polymeric materials, ground-powdered plastics, resins, bentonites, zeolites, titanium dioxide, iron oxides, hydroxides, aluminium oxides, hydroxides, organic materials such as bagasse, charcoal, synthetic organic polymers or mixture thereof.

The disintegrating agent of WG/WDG is selected from, but not limited to, citric acid, succinic acid, sodium bicarbonate or mixture thereof.

The humectants of WG/WDG is selected from, but not limited to, urea, humic acid, glycerol, lactose or mixture thereof.

Manufacturing process for Wettable granule/ Water Dispersible Granule (WG/ WDG):

Step 1: An exact weight of active ingredients is considered and a required quantity of binder(s) and surfactant(s) is/are added in the blender and mixed to achieve a complete homogenization.

Step 2: The homogenized mixture is milled to achieve required wet sieve and post blended to attain homogeneity.

Step 3: The above described homogenous material is passed through an extruder for granulation to achieve granular of require size.

Step 4: The wet granules are transferred through fluidized bed drier to remove excess moisture.

Step 5: The wet granules are further transferred to vibro shifter and further graded using vibrator screens.

Step 6: The final material is collected from the vibro shifter into drum.

Step 7: The sample is sent to QC for an approval.

Step 8: The material is transferred into the different size of drums when received an approval from QC.

E. List of inactive excipients used in the ZC formulation [mixed formulation of CS+SC]:

The mixed formulation (ZC) is a mixture of Capsule Suspension (CS) and Suspension Concentrates (SC). The mixed formulation (ZC) of the present invention comprises agrochemically acceptable excipients including, but not limited to, wall forming material(s) 1, wall forming material(s) 2, dispersing agent(s), wetting agent(s), wetting-spreading-penetrating agent(s), solvent(s), thickner(s), suspending agent(s), antifoaming agent(s), antifreezing agent(s), preservative(s), emulsifier(s) and buffering agent(s). Since the excipients for SC are the same, only the excipients for CS are listed here.

The wall forming material 1 of ZC is selected from, but not limited to, tetramethylene diisocyanate, pentamethylene diisocyanate, hexamethylene diisocyanate, toluene diisocyanate, 4,4-diphenylmethenediisocyanate (MDI), polymethylene polyphenylene isocyanate, 2,4,4’-diphenyl ether tri-isocyanate, 3,3’-dimethyl-4,4’-diphenyl diisocyanate, 3,3’-dimethoxy-4,4’-diphenyl diisocyanate, 1,5-naphthylene diisocyanate, 4,4’4"-triphenylmethane tri-isocyanate, toluene diisocyanate, polymethylene polyphenylisocyanate, polyurethane comprising of polyfunctional isocyanate, a polyamine in polarized form or mixture thereof.

The wall forming material 2 of ZC is selected from, but not limited to, Diethylene triamine, Ammonia, hexamine, ethylenediamine, propylene-1,3-diamine, tetramethylenediamine, pentamethylenediamine, 1,6-hexamethylenediamine, diethylenetriamine, triethylenetetramine, tetraethylenepentamine, pentaethylenehexamine, 4,9-dioxadodecane-1, 12-diamine, 1,3-phenylenediamine, 2,4-toluenediamine, 2,6-toluenediamine, 4,4’-diaminodiphenylmethane, 1,3-phenylenediamine, 1,5-diaminonaphthalene, 1,3,5-triaminobenzene, 2,4,6-triaminotoluene, 1,3,6-triaminonaphthalene, 2,4,4'-triaminodiphenyl ether, 3,4,5-triamino-1,2,4-triazole, 1,4,5,8-tetraminoanthraquinone or mixture thereof.

The solvent of ZC is selected from, but not limited to, hydrocarbon solvent such as an aliphatic, cyclic, aromatic hydrocarbons, toluene, xylene, paraffin, tetrahydronaphthalene, alkylated naphthalene, their derivatives, mineral oil fractions of medium to high boiling point such as kerosene, diesel oil, coal tar oils, a vegetable oil such as corn oil, rapeseed oil, a fatty acid ester such as C1-C10-alkylester of a C10-C22-fatty acid, methyl-ethyl esters of vegetable oils such as rapeseed oil methyl ester, corn oil methyl ester, acetophenone, 2-heptanon, 3-heptanone, 2-hexanone, 5-methyl-2-hexanone , 5-methyl-3-heptanone, 3-methyl-2-hexanone, 4-methyl-2-hexanone, 2-methyl-3-hexanone, 4-methyl-3-hexanone, 5-methyl-3-hexanone, 3-ethyl-2-pentanone, 3,3-dimethyl-2-pentanone, 3,4-dimethyl-2-pentanone, 4,4-dimethyl-2-pentanone, 2,2-dimethyl-3-pentanone , 2,4-dimethyl-3-pentanone, 2-octanone, 2,5-dimethyl-3-hexanone, 2,2-dimethyl-3-hexanone, 3,3-dimethyl-2-hexanone, 3,4-dimethyl-2-hexanone, 4,4-dimethyl-3-hexanone, 3-ethyl-4-methyl-2-pentanone, 2-methyl-3-heptanone, 2-methyl-4-heptanone, 3-methyl-2-heptanone, 3-methyl-4-heptanone, 5-methyl-3-heptanone, 6-methyl-2-heptanone, 6-methyl-3-heptanone, 3-octanone, 4-octanone, 2,2,4-trimethyl-3-pentanone, 3-ethyl-3-methyl-2-pentanone, 5-methyl-2-heptanone, isoprene or mixture thereof.

The buffering agent of ZC is selected from, but not limited to, sodium hydroxide, potassium hydroxide, acetic acid, sulphuric acid, hydrochloric acid, ortho phosphoric acid, ammonium hydroxide or mixture thereof.

The emulsifier of ZC is selected from, but not limited to, alkylbenzene sulfonate calcium salts, tristyrlphenol polyethoxyester phosphate or mixture thereof.

Manufacturing process for mixed formulation ZC:

Step 1: The aqueous phase - Charged water is added to a stainless steel vessel equipped with a high speed stirrer. The wetting agent(s), dispersing agent(s) 1 and dispersing agent(s) 2 is/are added into the vessel under agitation followed by the addition of 50% quantity of antifoam to avoid foam generation in this vessel.

Step 2: The organic phase - Charged heavy aromatic hydrocarbons solvent is added into second stainless-steel reactor followed by the addition of melted active ingredient into the reactor slowly. Afterwards, the wall forming material(s) 1 is/are charged to the reactor while mixing it. At last, the contents of the reactor are cooled down to room temperature.

Step 3: The high shear disperser of aqueous phase is initiated and the ‘organic solution’ is charged into the ‘aqueous phase solution’ under gravity at a specific rate to achieve the required particle size followed by shearing for 30 min. Initiate the reactor to heat around 50°C by stirring the formulation under slow rpm for 3-4 hours for the completion of polymerization reaction.

Step 4: The wall forming material(s) 2 is/are added so that the residual wall forming material(s) 1 can be consumed. Stir the same for 1 hour at the same temperature. Upon requirement, half quantity of the antifoam can be added to remove foam generation caused due to CO2 during the reaction.

Step 5: Upon the completion of wall polymerization reaction, the agitator’s speed is increased. The remaining half quantity of the antifoam(s) is/are added to the formulation. The mixture is allowed to de-gas for approximately 30 minutes to remove CO2 from the solution under slight vacuum. The linear polysaccharide(s), preservative(s) and at last freezing agent(s) is/are added and mixed for few minutes. At last, buffering agent(s) is/are added for pH adjustment and mixed well.

Step 6: The final product is sent for the approval of QC.

Step 7: Upon the approval, the material is packed in its required pack sizes.

EXAMPLES
The present invention has been described with reference to specific embodiment which is merely illustrative and not intended to limit the scope of the invention as defined in the present complete specification.
Biological Examples:

The synergistic pesticide action of the inventive mixtures can be demonstrated by the experiments below. A synergistic effect exists wherever the action of a combination (ready-mix) or tank mix of active ingredient is greater than the sum of the action of each of the compounds alone. Therefore, a synergistically effective amount or an effective amount of a synergistic composition or combination is an amount that exhibits greater pesticide activity than the sum of the pesticide activities of the individual compounds.

In the field of agriculture, it is often understood that the term “synergy” is as defined by Colby S.R. in an article entitled “ Calculation of the synergistic and antagonistic responses of herbicide combinations” published in the journal Weeds, 1967, 15, p.20-22, incorporated herein by reference in its entirety. The action expected for a given combination of two or three active compounds can be calculated as follows:

The objective of the present studies was to study the synergism and benefits of present compositions.

Example 1: Pod borer larval control in chickpea.
Crop : Chickpea
Location : Chhindwara, Madhya Pradesh
Treatments : 12
Crop age : 75 days after sowing.
Spray water volume : 400 liters per hectare.
Method of Application: Foliar spray with battery operated knapsack sprayer fitted with hollow cone nozzle.

Observation Methods:
Pod borer (Helicoverpaarmigera) larval control (%): Count the number of live larvae per plant. Record observations from 10 plants per plot on 14th days after application.

Composition of Compound A 30% + Compound B 7% + Compound C1 8% WG [T1 of Ex. 1]
Chemical composition Function Percent (w/w)
Compound A a.i. Compound A 30.00
Compound B a.i. Compound B 7.00
Compound C1 a.i. Compound C 8.00
Alkyl naphthalene sulfonate Dispersing agent I 6.00
Modified polyacrylate copolymer Dispersing agent II 4.00
Sodium isopropyl naphthalene sulfonate Wetting agent 5.00

Polydimethylsiloxane Antifoaming Agent 1.00
Lactose anhydrous Carrier 15.00
China clay Carrier 24.00
Total 100.00
Active ingredient on 100% purity basis

Storage Stability: Composition of Compound A 30% + Compound B 7% + Compound C1 8% WG [T1 of Ex. 1]
Laboratory storage stability for 14 days [T1 of Ex. 1]
Parameters Specifications Initial At 54±2 °C At 0±2 °C
Compound A a.i. 29.10 to 31.50 31.36 31.30 31.36
Compound B a.i. 6.65 to 7.35 7.32 7.29 7.32
Compound C1 a.i. 7.60 to 8.40 8.36 8.34 8.36
Compound A suspensibility (%) 70 98.40 97.30 98.20
Compound B suspensibility (%) 70 98.20 97.50 98.20
Compound C1 suspensibility (%) 70 98.80 97.40 98.60
pH range (1% aq. Suspension) 5 to 9 7.50 7.60 7.50
Wettability Max 30 s 10.00 12.00 10.00
Wet Sieve(45 micron) Mini 98.5% 99.50 99.40 99.50
Bulk Density 0.45-0.85 0.50 0.50 0.50
Moisture Content Max 2.0% 1.40 1.20 1.40
Persistent foam ml (after 1 minute) max. 60 nil nil nil

Room temperature storage stability up to 12 months [T1 of Ex. 1]
Parameters Specifications 1 month 6 month 12 month
Compound A a.i. 19.4 to 21 31.36 31.36 31.30
Compound B a.i. 6.65 to 7.35 7.32 7.32 7.29
Compound C1 a.i. 7.6 to 8.4 8.36 8.36 8.34
Compound A suspensibility (%) 70 98.40 98.40 98.30
Compound B suspensibility (%) 70 98.20 98.10 98.10
Compound C1 suspensibility (%) 70 98.80 98.80 98.70
pH range (1% aq. Suspension) 5 to 9 7.50 7.50 7.55
Wettability Max 30 s 10.00 10.00 11.00
Wet Sieve(45 micron) Mini 98.5% 99.50 99.50 99.50
Bulk Density 0.45-0.85 0.50 0.50 0.50
Moisture Content Max 2.0% 1.40 1.40 1.30
Persistent foam ml (after 1 minute) max. 60 nil nil nil
The composition of Compound A 30%+Compound B 7%+Compound C1 8% WG meets the all inhouse specifications for storage stability studies in laboratory (at 54±2 °C and At 0±2 °C for 14 days) and room temperature (for 12 months)

Manufacturing process for 100 kg batch of Compound A 30%+Compound B 7%+Compound C1 8% WG [T1 of Ex. 1]

Step 1: china clay (24 kg), lactose anhydrous (15 kg), silicone antifoam (0.5 kg), sodium isopropyl naphthalene sulfonate (5 kg), alkyl naphthalene sulfonate (6 kg) and modified polyacrylate copolymer (4 kg) were charged into a premix blender and homogenized for 30 minutes.

Step 2: Compound A (30 kg), compound B (7 kg) and compound C1 (8 kg) were also charged and homogenized for 30 minutes and this pre-blended material was grinded through jet mill/ air classifier mills. Further, finely grinded material was blended in post blender till it became homogeneous. (For approx 1.5 hr)
Step 3: Finely grinded powder was mixed with water (12 kg) having silicone antifoam (0.5 kg) to form extrudable dough.

Step 4: The dough was passed through extruder to achieve granules of required size.

Step 5: Wet granules was passed through fluidized bed drier to remove extra water (12 kg). Further it was added and graded using vibrating screens.

Step 6: Final product was sent for QC approval.

Step 7: Upon getting approval, the material was packed in required package sizes.

Table 1: Treatment details [Ex 1]

Sr. No. Treatment compositions gram actives per hectare
T1 Compound A 30%+Compound B 7%+Compound C1 8% WG 120+28+32
T2 Compound A 30%+Compound B 7%+Compound C2 10% WG 120+28+40
T3 Compound A 24% SC + Compound B 10% EC (tank mix) 120+28
T4 Compound A 24%+Compound C1 7% WG (ready mix) 120+32
T5 Compound A 24%+Compound C2 10% WG (ready mix) 120+40
T6 Compound B 10% EC + Compound C1 20% SP (tank mix) 28+32
T7 Compound B 10% EC + Compound C2 50% WDG (tank mix) 28+40
T8 Compound A 24% SC 120
T9 Compound B 10% EC 28
T10 Compound C1 20% SP 32
T11 Compound C2 50% WDG 40
T12 Untreated Check (UTC) -
T1 and T2 are present compositions, whereas T3 to T7 are known combinations and T8 to T11-market products.

Table 2: Residual control of pod borer larval in chickpea [Ex 1]

Treatment Number Pod borer larval control (%)
at 7 days at 14 days
Control observed Control Expected Colby's ratio Synergism (Y/N) Control observed Control Expected Colby's ratio Synergism (Y/N)
T1 100.0 92.1 1.09 Y 92.6 78.4 1.18 Y
T2 100.0 92.3 1.08 Y 90.6 79.4 1.14 Y
T3 91.8 90.3 1.02 Y 73.6 77.5 0.95 N
T4 75.0 73.5 1.02 Y 46.8 52.3 0.89 N
T5 76.4 74.1 1.03 Y 50.2 54.5 0.92 N
T6 78.2 75.8 1.03 Y 48.4 56.7 0.85 N
T7 78.4 76.3 1.03 Y 52.2 58.7 0.89 N
T8 67.4 50.2
T9 70.2 54.8
T10 18.8 4.2
T11 20.4 8.6
T12 0.0 0.0

The present compositions (T1 and T2) show synergism in terms of larvae control and provide residual control of pod borer larvae infesting chickpea.

Conclusion: Among the various compositions as shown in Table 1 treatment number T1 and T2 are considered to be present inventive compositions which showed excellent synergism and effectiveness against pod borer larval control at 7 DAA and 14 DAA [days after application] for more than 90%. Particularly, at 7 DAA the pod borer larval control for T1 to T2 were 100% whereas at 14 DAA the pod borer larval control observed were (T1) 92.6% followed by (T2) 90.6% . Moreover, the colby’s ratio was found to be >1 which shows strong synergism, when compared with known combinations and market products.

Example 2: Control of Leaf eating caterpillar infesting groundnut crop
Crop : Groundnut
Location : Gondal, Gujarat
Number of Treatments: 12
Plot size : 50 sq.m. (m2)
Crop stage : 68 days after sowing.
Method of application: Foliar spray with battery operated backpacksprayer.
Water volume : 375 liter per hectare

Observation Methods
Leaf eating caterpillar (Spodoptera litura) larval control (%): Count the number of live larvae per plant. Record observations from 10 plants per plot and calculate larval control as per formula given in example 1.

Composition of Compound A 20% + Compound B 5% + Compound C4 2.5% ZC [T2 of Ex. 2]
Chemical composition Function Content (w/w)
Compound A a.i. Compound A 20.00
Compound B a.i. Compound B 5.00
Compound C4 a.i. Compound C 2.50
Mixture of heavy aromatic hydrocarbons Solvent 5.00
4,4’-diphenylmethane diisocynate Wall forming material- I 0.25
Diethylene triamine Wall forming material-II 0.15

Alkylbenzene sulfonate calcium salts Emulsifier-I 0.12
Tristyrylphenol polyethoxyester phosphate Emulsifier-II 3.50
Sodium naphthalene sulphonate formaldehyde condensate Dispersing agent-II 0.16
Acrylic graft copolymer Dispersing agent-I 2.50

Attapulgite clay Suspending agent 1.50
Polydimethylsiloxane Anti foaming agent 0.30
1,2-benzisothiazolin Preservative 0.20
Polypylene glycol Anti freezing agent 5.00
Xanthan gum thickner 0.20
Diluent water 53.62
Total 100.00
Active ingredient on 100% purity basis

Storage stability-Composition of Compound A 20% + Compound B 5% + Compound C4 2.5% ZC [T2 of Ex. 2]
Laboratory storage stability for 14 days [T2 of Ex. 2]
Parameters Specifications Initial At 54±2 0C At 0±2 0C
Compound A a.i. 19.4 to 21 20.80 20.78 20.80
Compound B a.i. 4.75 to 5.25 5.22 5.18 5.22
Compound C4 a.i. 2.375 to 2.625 2.58 2.55 2.58
Compound A suspensibility (%) 80 98.90 98.91 98.90
Compound B suspensibility (%) 80 99.00 99.10 99.00
Compound C4 suspensibility (%) 80 6.90 98.80 98.80
pH range (1% aq. Suspension) 5.5 to 8.0 98.20 6.90 6.90
Pourability(%) 95 1.03 98.20 98.20
Specific gravity 1.05-1.10 99.50 1.03 1.03
Viscocity at spindle no.62,20 rpm 350-800 cps 510 510 510
Particle size(micron) D50<3,D90<10 2.1,8.0 2.1,8.0 2.1,8.0
Persistent foam ml (after 1 minute) max. 60 nil nil nil

Room temperature storage stability up to 12 months [T2 of Ex. 2]
Parameters Specifications 1 month 6 month 12 month
Compound A a.i. 19.4 to 21 20.80 20.78 20.80
Compound B a.i. 4.75 to 5.25 5.22 5.18 5.22
Compound C4 a.i. 2.375 to 2.625 2.58 2.55 2.58
Compound A suspensibility (%) 80 98.90 98.91 98.90
Compound B suspensibility (%) 80 99.00 99.10 99.00
Compound C4 suspensibility (%) 80 6.90 98.80 98.80
pH range (1% aq. Suspension) 5.5 to 8.0 98.20 6.90 6.90
Pourability (%) 95 1.03 98.20 98.20
Specific gravity 1.05-1.10 99.50 1.03 1.03
Viscocity at spindle no.62,20 rpm 350-800 cps 510 510 510
Particle size(micron) D50<3,D90<10 2.1,8.0 2.1,8.0 2.1,8.0
Persistent foam ml (after 1 minute) max. 60 nil nil nil
The composition of Compound A 20% + Compound B 5% + Compound C4 2.5% ZC meets the all inhouse specifications for storage stability in laboratory (at 54±2 °C and At 0±2 °C for 14 days) and room temperature (for 12 months)

Manufacturing process for 100 kg batch of Compound A 20% + Compound B 5% + Compound C4 2.5% ZC [T2 of Ex. 2]
Step 1: Preparation of 2% xanthan gum solution: xantham gum (2 kg) and 1,2-benz isothiazoline-3-one (2 kg) were charged into water (96 kg) and homogenized for 12 to 18 hours prior to use.

Step 2: Preparation of CS premix: Mixture of heavy aromatic carbon (5 kg) was added into other vessel having slow stirring. Compound C4 (2.5 kg) and of alkylbenzene sulfonate calcium salts (0.12 kg), 4,4’-diphenylmethane diisocynate (0.25 kg) were also added and mixed properly for 30 to 45 minutes.

Step 3: This premix was mixed with water (20 kg) and sodium naphthalene sulphonate formaldehyde condensate (0.16 kg) under high stirring and then diethylene triamine (0.15 kg) were added and stirerd at 50°C for 3 hours and finally 2% gum solution was added (2 kg).

Step 4: DM water (23.62 kg) and 1, 2-propylene glycol (5 kg) were added into designated vessel and mixed thoroughly.

Step 5: Aluminium magnesium silicate (0.5 kg), acrylic graft copolymer (2.5 kg), tristyrylphenol polyethoxyester phosphate (3.5 kg) and polydimethylsiloxane (0.1 kg) were added into vessel having water and the contents were homogenize for 45 to 60 minutes using high shear homogenizer.
Step 6: Then compound A (20 kg) and compound B (5 kg) were added to this premix slowly and homogenized to get uniform slurry ready for grinding.

Step 7: Before grinding half the quantity of antifoam was added and then material was subjected to grinding in dyno mill till desired particle size was achieved.

Step 8: Remaining polydimethyl siloxane antifoam (0.1 kg) was added after grinding process completes and before sampling for in process analysis.

Step 9: CS premix was mixed to this milled slurry under slow stirring and homogenized for 30 to 45 minutes.

Step 10: 2% Xanthan gum solution (10 kg) was added to this formulation and send to QC for quality check.

Table 3: Treatment details [Ex 2]

Treatment Number Treatment compositions gram actives per hectare
T1 Compound A 20%+Compound B 5%+Compound C3 7.5% SE 100+25+37.5
T2 Compound A 20%+Compound B 5%+Compound C4 2.5% ZC 100+25+12.5
T3 Compound A 24% SC + Compound B 10% EC (tank mix) 100+25
T4 Compound A 24% SC + Compound C3 10% EC (tank mix) 100+37.5
T5 Compound A 24% SC + Compound C4 5% EC (tank mix) 100+12.5
T6 Compound B 5%+Compound C3 7.5% EC (ready mix) 25+37.5
T7 Compound B 10%+Compound C4 5% EC (ready mix) 25+12.5
T8 Compound A 24% SC 100
T9 Compound B 10% EC 25
T10 Compound C3 10% EC 37.5
T11 Compound C4 5% EC 12.5
T12 Untreated Check (UTC) -
T1 and T2 are present compositions, whereas T3 to T7 are known combinations and T8 to T11-market products.

Table 4: Larval control of leaf eating caterpillar in groundnut crop [Ex 2]

Treatment Number Spodoptera larval control (%)
at 5 DAA at 15 DAA
control observed control expected Colby's ratio Synergism (Y/N) control observed control expected Colby's ratio Synergism (Y/N)
T1 100.0 94.6 1.06 Y 96.8 88.7 1.09 Y
T2 99.2 93.9 1.06 Y 93.4 87.7 1.07 Y
T3 90.4 88.6 1.02 Y 78.4 80.9 0.97 N
T4 86.2 84.6 1.02 Y 68.4 75.3 0.91 N
T5 84.0 82.5 1.02 Y 65.6 73.0 0.90 N
T6 85.2 83.5 1.02 Y 67.6 72.8 0.93 N
T7 82.2 81.2 1.01 Y 66.0 70.3 0.94 N
T8 67.4 58.4
T9 65.0 54.2
T10 52.8 40.6
T11 46.4 35.2
T12 0.0 0.0
Abbreviation: DAA- days after application.
The present compositions (T1 and T2) show synergism in terms of larvae control and provide residual control of leaf eating caterpillar infesting groundnut crop.

Conclusion: Among the various compositions as shown in Table 3, T1 and T2 are the present compositions which showed excellent synergism in terms of spodoptera larveal control and provide control of leaf eating caterpillar in ground nut crop. Further, (T1) showed 100% control followed by (T2) 99.2 % control against Spodoptera larval control at 5 DAA. Moreover, (T1) showed 96.8% followed by (T2) 93.4% showed against spodoptera larval contro at 15 DAA. At last, the colby’s ratio observed was >1 which means strong synergism, when compared with known combinations and market products.

Example 3: Fruit borer larval control in okra
Crop : Okra
Location : Sonipat, Haryana
Treatments : 12
Crop age : 50 days after sowing.
Spray water volume : 400 liters per hectare.
Method of Application: Foliar spray with battery operated knapsack sprayer fitted with hollow cone nozzle.

Observation Methods:
Sucking pest complex (includes Jassid, Amrascabiguttulabiguttula; Whitefly, Bemisiatabaci; Aphid, Aphis gossypii).
Count the number of live sucking pests (jassid, whitefly and aphid) per leaf, 3 leaves per plant and 10 plants per plot on 3rd and 10thDAA. Calculate sucking pests control (%) as observed control and apply Colby’s formula to calculate synergism.

Table 5: Treatment details [Ex 3]

Treatment Number Treatment compositions gram actives per hectare
T1 Compound A 10%+Compound B 2.5%+Compound C5 30% WP 150+37.5+400
T2 Compound A 15%+Compound B 3.75%+Compound C6 30% WG 150+37.5+300
T3 Compound A 24% SC + Compound B 10% EC (tank mix) 150+37.5
T4 Compound A 24% SC + Compound C5 75% SP (tank mix) 150+400
T5 Compound A 24% SC + Compound C6 50% EC (tank mix) 150+300
T6 Compound B 10% EC + Compound C5 75% SP (tank mix) 37.5+400
T7 Compound B 3.75%+Compound C6 30% EC (ready mix) 37.5+300
T8 Compound A 24% SC 150
T9 Compound B 10% EC 37.5
T10 Compound C5 75% SP 400
T11 Compound C6 50% EC 300
T12 Untreated Check (UTC) -
T1 and T2 are present compositions, whereas T3 to T7 are known combinations and T8 to T11 are market products.

Table 6: Control of sucking pests infesting okra crop [Ex 3]

Treatment Number Sucking pest control (%)
at 3 DAA at 10 DAA
control observed control expected Colby's ratio Synergism (Y/N) control observed control expected Colby's ratio Synergism (Y/N)
T1 97.4 91.8 1.06 Y 90.2 85.4 1.06 Y
T2 98.8 92.7 1.07 Y 91.6 85.7 1.07 Y
T3 80.2 78.1 1.03 Y 65.6 67.9 0.97 N
T4 71.6 72.0 1.00 Y 57.2 61.2 0.93 N
T5 74.8 75.1 1.00 Y 57.4 61.9 0.93 N
T6 90.4 88.9 1.02 Y 78.8 82.9 0.95 N
T7 91.2 90.2 1.01 Y 80.4 83.2 0.97 N
T8 25.4 14.6
T9 70.6 62.4
T10 62.4 54.6
T11 66.6 55.4
T12 0.0 0.0

Both the present compositions (T1 to T2) show synergism in terms of sucking pests control and provide residual on 3rd and 10thday, whereas known tank mixes (T3 to T7) show synergism on 3rdday only and does not provide residual control.

Both the present compositions (T1 to T2) show strong synergism as compared to known tank mixes (T3 to T7). Higher the Colby’s ratio means stronger the synergism.

Conclusion: Among the various compositions as shown in table 5, T1 and T2 are the present compositions which show excellent results in terms of sucking pest control in okra crop. In particular, at 3 DAA (T2) showed 98.8% followed by (T1) showed 97.4% control against sucking pest control. Further at 10 DAA (T2) showed 91.6% whereas (T1) showed 90.2% control as compared to the known compositions and market products. At last, the colby’s ratio observed for the present invention was >1 which means strong synergism compared to market products.

Example 4: Control of rice leaf folder
Crop : Rice
Location : Kurud, Chhattisgarh
Treatments : 7
Spray water volume : 450 liters per hectare.
Method of Application: Foliar spray with battery operated knapsack sprayer fitted with hollow cone nozzle.

Observation Methods:
Leaf folder larval control (%): Calculate number of live larvae per hill. Record the observations from 10 hills per plot and calculate leaf folder larval control.

Table 7: Treatment details [Ex 4]

Treatment Number Treatment compositions gram actives per hectare
T1 Compound A 12%+Compound B 2.5%+Compound C7 hydrogen oxalate 30% WG 120+25+300
T2 Compound A 12%+Compound B 2.5%+Compound C8 30% WG 120+25+300
T3 Compound A 24% SC 120
T4 Compound B 10% EC 25
T5 Compound C7 hydrogen oxalate 50% SP 300
T6 Compound C8 50% SP 300
T7 Untreated Check (UTC) -
T1 and T2 are present compositions and T3 to T6 are market products.

Table 8: Control of rice leaf folder [Ex 4]

Treatment Number Leaf folder larval control (%)
at 3 DAA at 10 DAA
control observed control expected Colby's ratio Synergism (Y/N) control observed control expected Colby's ratio Synergism (Y/N)
T1 100.0 94.5 1.06 Y 98.0 89.0 1.10 Y
T2 100.0 94.3 1.06 Y 96.0 88.6 1.08 Y
T3 64.0 56.0
T4 62.0 52.0
T5 60.0 48.0
T6 58.0 46.0
T7 0.0 0.0

The present compositions (T1 and T2) show synergism in terms of rice leaf folder larval control and provide residual control.

Conclusion: Among the various compositions as shown in table 7, T1 and T2 are the present compositions which show very good results in terms of rice leaf folder larval control and provide residual control in rice crop. In particular, at 3 DAA T1 and T2 showed 100% control against rice leaf folder larval control. Further at 10 DAA (T1) showed 98% control followed by (T2) showing 96% control in rice plant as compared to the known compositions and market products. At last, the colby’s ratio observed for the present invention was >1 which means strong synergism.

Example 5: Pod borer larval control and yield in red gram.
Crop : Red gram
Location : Udalpur, Vadodara, Gujarat
Treatments : 20
Crop age : 108 days after sowing.
Spray water volume : 480 liters per hectare.
Method of Application: Foliar spray with battery operated knapsack sprayer fitted with hollow cone nozzle.

Observation Methods:
Pod borer (Helicoverpaarmigera) larval control (%): Count the number of live larvae per plant. Record observations from 10 plants per plot on 14th days after application.

Pod count: count the number of healthy and damaged (by pod borer larvae) pods of red gram per plant. Record the observations from 10 plants per plot.

Composition of Compound A 20% + Compound B 4% + Compound C11 1.2% SC [T3 of Ex. 5]
Chemical composition Function Content (w/w)
Compound A a.i. Compound A 20.00
Compound B a.i. Compound B 4.00
Compound C11 a.i. Compound C 1.20
Methylated seed oil, polyalkyleneoxide modified trisiloxane Super wetting-spreading-penetrating agent 7.50
Ethylene-propylene oxide block copolymer Dispersing agent I 5.00
Sodium naphthalene sulphonate formaldehyde condensates Dispersing agent II 1.25

Aluminum magnesium silicate Suspending agent 0.50
Polydimethylsiloxane
Anti foaming agent 0.30
Sodium benzoate Preservatives 0.20
Polypropylene glycol Anti freezing agent 5.00

Xanthan gum thickner 0.20
Diluent water 54.85
Total 100.00
Active ingredient on 100% purity basis

Storage stability-Composition of Compound A 20% + Compound B 4% + Compound C11 1.2% SC [T3 of Ex. 5]
Laboratory storage stability for 14 days [T3 of Ex. 5]
Parameters Specifications Initial At 54±2 0C At 0±2 0C
Compound A a.i. 19.4 to 21 20.80 20.76 20.8
Compound B a.i. 3.8 to 4.2 4.18 4.12 4.18
Compound C11 a.i. 1.14 to 1.26 1.25 1.23 1.25
Compound A suspensibility (%) 80 98.60 98.10 98.50
Compound B suspensibility (%) 80 98.50 98.30 98.50
Compound C11 suspensibility (%) 80 98.70 98.20 98.45
pH range (1% aq. Suspension) 5.5 to 8.0 7.05 7.15 7.05
Pourability(%) 95 98.20 98.00 98.10
Specific gravity 1.05-1.10 1.07 1.07 1.07
Viscocity at spindle no.62,20 rpm 350-800 cps 530 550 550
Particle size(micron) D50<3,D90<10 2.1,8.5 2.1,8.7 2.1,8.7
Persistent foam ml (after 1 minute) max. 60 nil nil nil

Room temperature storage stability up to 12 months [T3 of Ex. 5]
Parameters Specifications 1 month 6 month 12 month
Compound A a.i. 19.4 to 21 20.80 20.80 20.76
Compound B a.i. 3.8 to 4.2 4.18 4.18 4.17
Compound C11 a.i. 1.14 to 1.26 1.25 1.25 1.23
Compound A suspensibility (%) 80 98.50 98.50 98.40
Compound B suspensibility (%) 80 98.50 98.50 98.40
Compound C11 suspensibility (%) 80 98.70 98.60 98.60
pH range (1% aq. Suspension) 5.5 to 8.0 7.05 7.05 7.10
Pourability (%) 95 98.20 98.20 98.10
Specific gravity 1.05-1.10 1.07 1.07 1.07
Viscocity at spindle no.62,20 rpm 350-800 cps 530 530 535
Particle size(micron) D50<3,D90<10 2.1,8.5 2.1,8.5 2.1,8.6
Persistent foam ml (after 1 minute) max. 60 nil nil nil
The composition of Compound A 20% + Compound B 4% + Compound C11 1.2% SC meets the all inhouse specifications for storage stability in laboratory (at 54±2 °C and At 0±2 °C for 14 days) and room temperature (for 12 months).

Manufacturing Process for 100 kg batch of Compound A 20% + Compound B 4% + Compound C11 1.2% SC [T3 of Ex. 5]

Step 1: Preparation of 2% gum solution: Xanthan gum (2.0 kg) and sodium benzoate (2.0 kg) were charged into water (96 kg) and homogenized. It was prepared 12 to 18 hours prior to use.

Step 2: DM water (44.85 kg) and 1, 2-propylene glycol (5 kg) were charged into designated vessel and mix thoroughly.

Step 3: Sodium naphthalene sulphonate formaldehyde condensates (1.25 kg), ethylene-propylene oxide block copolymer (5.00 kg) and aluminium magnesium silicate (0.5 kg) were added into the vessel having water and the contents were homogenized for 45-60 minutes using high shear homogeniser.

Step 4: Compound A (20 kg), compound B (4 kg) and compound C11 (1.2 kg) were added to this premix slowly and homogenized to get uniform slurry ready for grinding.

Step 5: Before grinding half the quantity of polydimethylsiloxane (0.15 kg) was added and then material was subjected to grinding in dyno mill till desired particle size is achieved.

Step 6: Remaining polydimethyl siloxane (0.15 kg) antifoam was added after grinding process completes and before sampling for in process analysis.

Step 7: Finally 2% xantham gum solution (10 kg) and methylated seed oil, polyalkylenoxide modified trisiloxane (7.5 kg) were added to this formulation and homogenized for 30 minutes.

Step 8: This final formulation was sent to QC for quality check.

Composition of Compound A 16% + Compound B 3.2% + Compound C12 5% OD [T4 of Ex. 5]
Chemical composition Function Content (w/w)
Compound A a.i. Compound A 16.00
Compound B a.i. Compound B 3.20
Compound C12 a.i. Compound C 5.00
Polyoxyethylene sobitol hexaoleate Oil Emulsifier 10.00
Salts of polyolefin condensates Non-Aqueous dispersant 2.50
Ethoxylated sorbitan ester Co-Emulsifier 8.50

Bentonite clay Rheology modifier 1.50
Styrene acrylic polymer Aqueous dispersant 1.50
Methylated seed oil Oil continuous phase 51.80
Total 100.00

Active ingredient on 100% purity basis

Storage stability-Composition of Compound A 16% + Compound B 3.2% + Compound C12 5% OD [T4 of Ex. 5]
Laboratory storage stability for 14 days [T4 of Ex. 5]
Parameters Specifications Initial At 54±2 0C At 0±2 0C
Compound A a.i. 15.20 to 16.80 16.66 16.62 16.66
Compound B a.i. 3.04 to 3.52 3.48 3.44 3.48
Compound C4 a.i. 4.75 to 5.50 5.45 5.41 5.45
Compound A suspensibility (%) 80 98.90 98.10 98.80
Compound B suspensibility (%) 80 99.00 98.50 98.90
Compound C4 suspensibility (%) 80 98.90 98.10 98.80
pH range (1% aq. Suspension) 5.5 to 8.0 6.90 7.05 6.90
Pourability(%) 95 98.20 98.10 98.20
Specific gravity 1.00-1.10 1.03 1.03 1.03
Viscocity at spindle no.62,20 rpm 350-800 cps 510 520 510
Particle size(micron) D50<3,D90<10 2.1,8.0 2.1,8.2 2.1,8.1
Persistent foam ml (after 1 minute) max. 60 nil nil nil

Room temperature storage stability up to 12 months [T4 of Ex. 5]
Parameters Specifications 1 month 6 month 12 month
Compound A a.i. 15.20 to 16.80 16.66 16.66 16.62
Compound B a.i. 3.04 to 3.52 3.48 3.48 3.44
Compound C12 a.i. 4.75 to 5.50 5.45 5.45 5.41
Compound A suspensibility (%) 80 98.90 98.80 98.10
Compound B suspensibility (%) 80 98.90 98.90 98.50
Compound C4 suspensibility (%) 80 98.80 98.80 98.10
pH range (1% aq. Suspension) 5.5 to 8.0 6.90 6.90 6.90
Pourability(%) 95 98.20 98.20 98.20
Specific gravity 1.05-1.10 1.03 1.03 1.03
Viscocity at spindle no.62,20 rpm 350-800 cps 510 510 515
Particle size(micron) D50<3,D90<10 2.1,8.1 2.1,8.1 2.1,8.1
Persistent foam ml (after 1 minute) max. 60 nil nil nil
The composition of Compound A 20% + Compound B 4% + Compound C12 7.5% OD meets the all inhouse specifications for storage stability in laboratory (at 54±2 °C and At 0±2 °C for 14 days) and room temperature (for 12 months).

Manufacturing Process for 100 kg batch of Compound A 16% + Compound B 3.2% + Compound C12 5% OD [T4 of Ex. 5]

Step 1: Preparation of 15% bentonite clay solution: Bentonite clay (15 kg) was added into methylated seed oil (85 kg) and homogenized till it gets completely dissolved. It must be kept for 12 to 18 hours prior to use.

Step 2: OD Premix: Methylated seed oil (41.8 kg) was charged into a designated vessel for OD production.

Step 3: Polyoxyethylene sorbitol hexaoleate (10 kg), styrene acrylic polymer (1.5 kg), ethoxylated sorbitan ester (8.5 kg), salts of polyolefin condensates (2.5 kg) and polydimethyl siloxane (0.15 kg) were added and the contents were homogenised for 45 to 60 minutes using high shear homogenizer.

Step 4: Compound A technical (16 kg), compound B technical (3.3 kg) and compound C12 technical (5 kg) were added into this premix and homogenized for 30 to 45 minutes.

Step 5: Remaining silicon antifoam (0.15 kg) and 15% bentonite clay solution (10 kg) were added after milling to avoid foaming.

Step 6: This final formulation was sent to QC for quality check.

Table 9: Treatment details [Ex 5]

Treatment Number Treatment compositions gram actives per hectare
T1 Compound A 20%+Compound B 4%+Compound C9 6% SC 125+25+37.5
T2 Compound A 20%+Compound B 4%+Compound C10 5% SC 125+25+31.25
T3 Compound A 20%+Compound B 4%+Compound C11 1.2% SC 125+25+7.5
T4 Compound A 16%+Compound B 3.2%+Compound C12 5% OD 125+25+39
T5 Compound A 24% SC + Compound B 10% EC (tank mix) 125+25
T6 Compound A 20%+Compound C9 6% SC (ready mix) 125+37.5
T7 Compound A 20%+Compound C10 5% SC (ready mix) 125+31.25
T8 Compound A 20%+Compound C11 1.2% SC (ready mix) 125+7.5
T9 Compound A 16%+Compound C12 5% SE (ready mix) 125+39
T10 Compound B 8%+Compound C9 12% SE (ready mix) 25+37.5
T11 Compound B 8%+Compound C10 10% SC (ready mix) 25+31.25
T12 Compound B 8%+Compound C11 2.4% EC (ready mix) 25+7.5
T13 Compound B 3.2%+Compound C12 5% EC (ready mix) 25+39
T14 Compound A 24% SC 125
T15 Compound B 10% EC 25
T16 Compound C9 45% SC 37.5
T17 Compound C10 11.7% SC 31.25
T18 Compound C11 5% SG 7.5
T19 Compound C12 10% EC 39
T20 Untreated Check (UTC) -
T1 to T4 are present compositions and T5 to T13 are known tank mixes.

Table 10: Control of pod borer larvae infesting red gram [Ex 5]

Treatment Number Pod borer larval control (%)
at 5 DAA at 15 DAA
control observed control expected Colby's ratio Synergism (Y/N) control observed control expected Colby's ratio Synergism (Y/N)
T1 100.0 96.0 1.04 Y 100.0 92.2 1.08 Y
T2 100.0 96.2 1.04 Y 100.0 92.6 1.08 Y
T3 100.0 95.7 1.04 Y 100.0 91.8 1.09 Y
T4 100.0 96.0 1.04 Y 100.0 92.0 1.09 Y
T5 91.2 90.3 1.01 Y 84.6 85.2 0.99 N
T6 87.2 86.9 1.00 Y 77.8 79.7 0.98 N
T7 88.0 87.6 1.00 Y 79.2 80.8 0.98 N
T8 87.2 86.1 1.01 Y 75.0 78.4 0.96 N
T9 87.4 86.9 1.01 Y 78.0 79.0 0.99 N
T10 88.0 87.2 1.01 Y 76.6 80.0 0.96 N
T11 88.4 87.9 1.01 Y 80.0 81.1 0.99 N
T12 87.6 86.3 1.01 Y 75.2 78.8 0.95 N
T13 88.2 87.1 1.01 Y 78.4 79.4 0.99 N
T14 68.6 61.2
T15 69.2 61.8
T16 58.4 47.6
T17 60.6 50.4
T18 55.6 44.4
T19 58.2 46.0
T20 0.0 0.0

All the present compositions (T1 to T4) provide synergistic and residual control of pod borer larvae.

Table 11: Pod damage and pod count [Ex 5]

Treatment Number Pod damage (%) Number of healthy pods per plant Increase (%) in fruits over UTC

T1 0.14 215.0 133.7
T2 0.11 218.0 137.0
T3 0.15 208.0 126.1
T4 0.17 212.0 130.4
T5 2.57 187.0 103.3
T6 3.14 170.0 84.8
T7 2.86 174.0 89.1
T8 3.88 163.0 77.2
T9 3.10 167.0 81.5
T10 3.16 172.0 87.0
T11 2.83 177.0 92.4
T12 3.32 164.0 78.3
T13 2.90 165.0 79.3
T14 7.18 126.0 37.0
T15 7.12 133.0 44.6
T16 7.82 138.0 50.0
T17 7.65 134.0 45.7
T18 8.24 140.0 52.2
T19 7.95 120.0 30.4
T20 28.56 92.0 0.0

All the present compositions (T1 to T4) yielded higher number of healthy pods per plant.

Conclusion: Among the various compositions as shown in table 9, T1 to T4 are the present composition which showed excellent synergism and effectiveness against pod borer larvae control and reduced pod damage in red gram. Further, T1-T4 showed 100% control at 5 DAA and 15 DAA. At last, the Colby’s ratio observed was >1 which means strong synergism.

Furthermore, T1-T4 showed less than 0.17% of pod damage. In particular, (T2) showed 0.11%, (T1) 0.14%, (T3) 0.15% pod damage. Moreover, the numbers of healthy pods per plant for T1-T4 were more 208. In particular, (T2) showed 218 followed by (T1) 215, (T4) 212 and (T3) 208 numbers of healthy pods per plant. At last, (T2) showed 137% followed by (T1) 133.7% (T4) 130.4% and (T3) 126.1% increase in healthy fruits over UTC [untreated check] from which it can be concluded that the present composition T1-T4 showcased effectiveness and synergism in red gram crop as compared to known compositions and market products.

Example 6: Red spider mite control in brinjal crop
Crop : Brinjal
Location : Umreth, Gujarat
Number of Treatments: 16
Plot size : 50 sq.m.
Crop age : 85 days after transplanting.
Method of application : Foliar spray with battery operated backpack sprayer.
Water volume : 480 liter per hectare

Observation Methods:
Red spider mite (Tetranychusurticae): Count the number of motile stages of mite per unit area using 10X pocket microscope. Record the observations from 5 spots on randomly selected leaves (young growing leaves) per plant. Observe 10 plants per plot. Calculate mite control (%) as per formula given for thrips control.

Composition of Compound A 20% + Compound B 4% + Compound C13 1% SE [T1 of Ex. 6]
Chemical composition Function Content (w/w)
Compound A a.i. Compound A 20.00
Compound B a.i. Compound B 4.00
Compound C13 a.i. Compound C 1.00
Polyarylphenyl anionic ether sulfate, ammonium salt Emulsifier-2 3.50
Aromatic solvent C-9 Solvent 10.00
Acrylic graft copolymer Dispersing agent I 3.00

Butyl Polyalkylene Oxide blockcopolymer Dispersing agent II 4.50
Aluminium magnesium silicate Suspending agent 0.50
Polydimethylsiloxane Anti foaming agent 0.20
1,2-benzisothiazolin-3(2H)-one preservative 0.15
Citric acid Buffering agent 0.10
Polypropylene glycol Anti freezing agent 5.00
Xanthan gum thickner 0.15
Diluent water 47.90
Total 100.00
Active ingredient on 100% purity basis

Storage stability-Composition of Compound A 20% + Compound B 4% + Compound C13 1% SE [T1 of Ex. 6]
Laboratory storage stability for 14 days [T1 of Ex. 6]
Parameters Specifications Initial At 54±2 0C At 0±2 0C
Compound A a.i. 19.4 to 21 20.80 20.75 20.80
Compound B a.i. 3.8 to 4.2 4.18 4.11 4.18
Compound C4 a.i. 0.95 to 1.05 1.04 1.03 1.04
Compound A suspensibility (%) 80 98.90 97.50 98.50
Compound B suspensibility (%) 80 99.00 97.90 98.60
Compound C4 suspensibility (%) 80 98.50 97.60 98.30
pH range (1% aq. Suspension) 4.5 to 7.0 5.50 5.50 5.50
Pourability(%) 95 98.20 98.20 97.80
Specific gravity 1.05-1.10 1.07 1.07 1.07
Viscocity at spindle no.62,20 rpm 350-800 cps 550 560 560
Particle size(micron) D50<3,D90<10 2.1,8.2 2.2,8.5 2.1,8.2
Persistent foam ml (after 1 minute) max. 60 nil nil nil

Room temperature storage stability up to 12 months [T1 of Ex. 6]
Parameters Specifications 1 month 6 month 12 month
Compound A a.i. 19.4 to 21 20.80 20.80 20.75
Compound B a.i. 3.8 to 4.2 4.18 4.18 4.11
Compound C12 a.i. 0.95 to 1.05 1.04 1.04 1.03
Compound A suspensibility (%) 80 98.70 98.70 98.50
Compound B suspensibility (%) 80 98.90 98.80 98.70
Compound C4 suspensibility (%) 80 98.40 98.40 98.40
pH range (1% aq. Suspension) 4.5 to 7.0 5.50 5.50 5.50
Pourability(%) 95 98.20 98.20 98.20
Specific gravity 1.05-1.10 1.07 1.07 1.07
Viscocity at spindle no.62,20 rpm 350-800 cps 550 550 555
Particle size(micron) D50<3,D90<10 2.1,8.1 2.1,8.1 2.1,8.1
Persistent foam ml (after 1 minute) max. 60 nil nil nil
The composition of Compound A 20% + Compound B 4% + Compound C13 1 % SE meets the all inhouse specifications for storage stability in laboratory (at 54±2 °C and At 0±2 °C for 14 days) and room temperature (for 12 months).

Manufacturing Process for 100 kg batch of Compound A 20% + Compound B 4% + Compound C13 1% SE [T1 of Ex. 6]

Step 1: Preparation of 2% gum solution: Xanthan gum (2 kg) and 1,2-benzisothiazoline-3-one (2 kg) were charged into 96 kg water and homogenized and it was prepared 12-18 hour prior to use.

Step 2: EC premix- Aromatic solvent C-9 (10 kg) was added into other vessel having slow stirring. Compound B technical (4 kg) and compound C13 (1 kg) and 3.5 kg of polyarylphenyl anionic ether sulfate, ammonium salt were also added and mixed properly for 30-45 minutes.

Step 3: Charge DM water (37.9 kg), 1,2-propylene glycol (5 kg) and citric acid (0.1 kg) into designated vessel and mix thoroughly.

Step 4: Aluminum magnesium silicate (0.5 kg), acrylic graft copolymer (3 kg), butyl polyalkylene oxide block copolymer (4.5 kg) and polydimethylsiloxane (0.1 kg) were added to the vessel having water and the contents were homogenized for 45 to 60 minutes using high shear homogenizer.

Step 5: Compound A (20 kg) was added to this premix slowly and homogenized to get uniform slurry ready for grinding.

Step 6: Before grinding half the quantity of antifoam was added and then material was subjected to grinding in dyno mill till desired particle size is achieved.

Step 7: Remaining polydimethyl siloxane antifoam (0.1 kg) was added after grinding process completed and before sampling for in process anlaysis.

Step 8: EC premix was mixed to this milled slurry under slow stirring and homogenized for 30 to 45 minutes.

Step 9: Finally 7.5 kg of 2% gum solution was added to this formulation and sent to QC for quality check.

Table 12: Treatment details [Ex 6]

Treatment Number Treatment compositions gram actives per hectare
T1 Compound A 20%+Compound B 4%+Compound C13 1% SE 150+30+7.5
T2 Compound A 20%+Compound B 4%+Compound C14 3% SE 150+30+22.5
T3 Compound A 20%+Compound B 4%+Compound C15 3% SE 150+30+22.5
T4 Compound A 13.33%+Compound B 2.67%+Compound C16 20% SC 150+30+225
T5 Compound A 24% SC + Compound B 10% EC (tank mix) 125+25
T6 Compound B 4%+Compound C13 1% SE 30+7.5
T7 Compound B 4%+Compound C14 3% SE 30+22.5
T8 Compound B 4%+Compound C15 3% SE 30+22.5
T9 Compound B 2.67%+Compound C16 20% SC 30+225
T10 Compound A 24% SC 125
T11 Compound B 10% EC 25
T12 Compound C13 1.8% EC 37.5
T13 Compound C14 5% EC 31.25
T14 Compound C15 5% SC 7.5
T15 Compound C16 50% WP 39
T16 Untreated Check (UTC) -
T1 to T4 are present compositions, whereas T5 to T9 are known combinations and T10 to T15 are market products.

Table 13: Control of red spider mite infesting brinjal crop [Ex 6]

Treatment Number Red spider mite control (%)
at 7 DAA
control observed control expected Colby's ratio Synergism (Y/N)
T1 98.4 83.8 1.17 Y
T2 98.2 85.4 1.15 Y
T3 97.8 85.1 1.15 Y
T4 96.4 82.4 1.17 Y
T5 62.4 63.1 0.99 N
T6 78.6 80.2 0.98 N
T7 79.2 82.1 0.96 N
T8 78.2 81.7 0.96 N
T9 77.4 78.5 0.99 N
T10 18.4
T11 54.8
T12 56.2
T13 60.4
T14 59.6
T15 52.4
T16 0.0

All the present compositions (T1 to T4) provide synergistic control of red spider mite infesting brinjal crop.

Conclusion: Among the various compositions as shown in table 12 the present compositions T1 to T4 showcases the red spider mite control. Further, the present compositions (T1) showed 98.4% control followed by (T2) 98.2%, (T3) 97.8% and (T4) 96.4% control at 7 DAA [days after application] in brinjal crop. Moreover, the Colby’s ratio was =1 for the present compositions which shows stronger synergism as compared to the known compositions and market products.

Example 7: Whitefly control in tomato crop
Crop : Tomato
Location : Umreth, Gujarat
Number of Treatments: 10
Plot size : 50 sq.m.
Crop age : 75 days after transplanting.
Method of application : Foliar spray with battery operated backpack sprayer.
Water volume : 420 liter per hectare

Observation Methods:
Whitefly (Bemisiatabaci): Count the number of live whitefly (adult+nymphs) per trifoliate leaf, 3 leaves per plant. Calculate whitefly control (%) as observed value and apply Colby’s formula to calculate synergism.

Table 14: Treatment details [Ex 7]

Treatment Number Treatment compositions gram actives per hectare
T1 Compound A 20%+Compound B 5%+Compound C17 10% SE 125+31.3+62.5
T2 Compound A 20%+Compound B 5%+Compound C18 8% WG 125+31.3+50
T3 Compound A 24% SC + Compound B 10% EC (tank mix) 125+31.3
T4 Compound B 5%+Compound C17 10% SE (ready mix) 31.3+62.5
T5 Compound B 10%+Compound C18 16% WG 31.3+50
T6 Compound A 24% SC 125
T7 Compound B 10% EC 31.3
T8 Compound C17 10% EC 62.5
T9 Compound C18 50% WG 50
T10 Untreated Check (UTC) -
T1 and T2 are present compositions, whereas T3 to T5 are known combinations and T6 to T9 are market products.

Table 15: Whitefly control [Ex 7]

Treatment Number Whitefly control (%)
at 7 DAA
control observed control expected Colby's ratio Synergism (Y/N)
T1 97.8 90.5 1.08 Y
T2 91.4 85.2 1.07 Y
T3 66.2 65.9 1.00 Y
T4 88.6 87.4 1.01 Y
T5 81.2 80.4 1.01 Y
T6 24.6
T7 54.8
T8 72.2
T9 56.6
T10 0.0

Both the present compositions (T1 and T2) provide synergistic control of whitefly infesting tomato crop.

Conclusion: Among the various compositions as shown in table 14, T1 and T2 are present invention and it showcases the whitefly control in tomato crop. Further, the present compositions (T1) showed 97.8% control followed by (T2) 91.4% control at 7 DAA [days after application] in tomato crop. Moreover, the Colby’s ratio was =1 for the present compositions which shows stronger synergism as compared to the known compositions and market products.

The process for preparing the insecticidal composition can be modified accordingly by any person skilled in the art based on the knowledge of the manufacturing the formulation. However, all such variation and modification is still covered by the scope of present invention.
Application to the seeds is carried out before sowing, either directly on the seeds or after having pregerminated the latter. Suitable application methods include inter alia soil treatment, seed treatment, in furrow application, and foliar application. Soil treatment methods include drenching the soil, drip irrigation (drip application onto the soil), dipping roots, tubers or bulbs, or soil injection. Seed treatment techniques include seed dressing, seed coating, seed dusting, seed soaking, and seed pelleting. In furrow applications typically include the steps of making a furrow in cultivated land, seeding the furrow with seeds, applying the pesticidally active composition to the furrow, and closing the furrow. Foliar application refers to the application of the pesticidally active composition to plant foliage, e.g. through spray equipment.
The rates of application vary within wide limits and depend on the nature of the soil, the method of application, the crop plant, the pest to be controlled, the prevailing climatic conditions, and other factors governed by the method of application, the time of application and the target crop.
The present invention is suitable for use in protecting crops, plants, plant propagation materials, such as seeds, or sailor water, in which the plants are growing, from attack or infestation by animal pests. Therefore, the present invention also relates to a plant protection method, which comprises contacting crops, plants, plant propagation materials, such as seeds, or soil or water, in which the plants are growing, to be protected from attack or infestation by animal pests, with a insecticidally effective amount of the present invention.
The present invention is also suitable for use in combating or controlling animal pests. Therefore, the present invention also relates to a method of combating or controlling animal pests, which comprises contacting the animal pests, their habitat, breeding ground, or food supply, or the crops, plants, plant propagation materials, such as seeds, or soil, or the area, material or environment in which the animal pests grow, with an insecticidally effective amount of the present invention.
The lists of crops on which the insecticidal composition of the present invention is used include, but not limited to GMO (Genetically Modified Organism) and Non GMO traits, hybrids and conventional varieties of Cotton (Gossypium spp.), Paddy (Oryza sativa), Wheat (Triticum aestavum), Barley (Hordeum vulgare), Maize (Zea mays), Sorghum (Sorghum bicolor), Oat (Avena sativa), Pearl millet (Pennisetum glaucum), Sugarcane (Saccharum officinarum), Sugar beet (Beta vulgaris), Soybean (Glycin max), Groundnut/Peanut (Arachis hypogaea), Sunflower (Helianthus annuus), Mustard (Brassica juncea), Rape seed (Brassica napus), Sesame (Sesamum indicum), Green gram (Vigna radiata), Black gram (Vigna mungo), Chickpea (Cicer aritinum), Cowpea (Vigna unguiculata), Red gram (Cajanus cajan), French bean (Phaseolus vulgaris), Indian bean (Lablab purpureus), Horse gram (Macrotyloma uniflorum), Field pea (Pisum sativum), Cluster bean (Cyamopsis tetragonoloba), Lentils (Lens culinaris), Brinjal (Solanum melongena), Cabbage (Brassica oleracea var. capitata), Cauliflower (Brassica oleracea var. botrytis), Okra (Abelmoschus esculentus), Onion (Allium cepa L.), Tomato (Solanum lycopersicun), Potato (Solanum tuberosum), Sweet potato (Ipomoea batatas), Chilly (Capsicum annum), Bell pepper (Capsicum annum), Garlic (Allium sativum), Cucumber (Cucumis sativus), Muskmelons (Cucumis melo), Watermelon (Citrullus lanatus), Bottle gourd (Lagenaria siceraria), Bitter gourd (Momordica charantia), Radish (Raphanus sativus), Carrot (Dacus carota subsp. sativus), Turnip (Brassica rapa rapa), Apple (Melus domestica), Banana (Musa spp.), Citrus groups (Citrus spp.), Grape (Vitis vinifera), Guava (Psidium guajava), Mango (Mangifera indica), Papaya (Carica papaya), Pineapple (Ananas comosus), Pomegranate (Punica granatum), Sapota (Manilkara zapota), Tea (Camellia sinensis), Coffea (Coffea Arabica), Turmeric (Curcuma longa), Ginger (Zingiber officinale), Cumin (Cuminum cyminum), Black Pepper (Piper nigrum), Mentha ( Mentha spp.), Rose (Rosa spp.), Jasmine (Jasminum spp.), Marigold ( Tagetes spp.), Common daisy (Bellis perennis), Dahlia (Dahlia hortnesis), Gerbera (Gerbera jamesonii), Carnation (Dianthus caryophyllus).
Crops are to be understood as also including those crops which have been rendered tolerant to herbicides or classes of herbicides (e.g. ALS-, GS-, EPSPS-, PPO-, ACCase- and HPPD-inhibitors) by conventional methods of breeding or by genetic engineering. An example of a crop that has been rendered tolerant to imidazolinones, e.g. imazamox, by conventional methods of breeding is Clearfield® summer rape (canola). Examples of crops that have been rendered tolerant to herbicides by genetic engineering methods include e.g. glyphosate- and glufosinate-resistant maize varieties commercially available under the trade names RoundupReady® and LibertyLink®.
Crops are also to be understood as being those which have been rendered resistant to harmful insects by genetic engineering methods, for example Bt maize (resistant to European corn borer), Bt cotton (resistant to cotton boll weevil) and also Bt potatoes (resistant to Colorado beetle). Examples of Bt maize are the Bt 176 maize hybrids of NK® (Syngenta Seeds). The Bt toxin is a protein that is formed naturally by Bacillus thuringiensis soil bacteria. Examples of toxins, or transgenic plants able to synthesise such toxins, are described in EP-A-451 878, EP-A-374 753, WO 93/07278, WO 95/34656, WO 03/052073 and EP-A-427 529. Examples of transgenic plants comprising one or more genes that code for an insecticidal resistance and express one or more toxins are KnockOut® (maize), Yield Gard® (maize), NuCOTIN33B® (cotton), Bollgard® (cotton), NewLeaf® (potatoes), NatureGard® and Protexcta®. Plant crops or seed material thereof can be both resistant to herbicides and, at the same time, resistant to insect feeding (“stacked” transgenic events). For example, seed can have the ability to express an insecticidal Cry3 protein while at the same time being tolerant to glyphosate.
Crops are also to be understood to include those which are obtained by conventional methods of breeding or genetic engineering and contain so-called output traits (e.g. improved storage stability, higher nutritional value and improved flavour).
Other useful plants include turf grass for example in golf-courses, lawns, parks and roadsides, or grown commercially for sod, and ornamental plants such as flowers or bushes.
The insecticidal composition of the present invention is used to control insects-pests and plant parasitic mites. The major insects pests are belongs to the order Hemiptera, for example, rice leafhopper/green leaf hopper (GLH) Nephotettix nigropictus, rice brown plant hopper (BPH) Nilaparvata lugen, rice backed plant hopper (WBPH) Sogatella furcifera , Apple Mealy bug Phenococcus aceris, bean aphid Aphis fabae, black citrus aphid Toxoptera aurantii, citrus black scale Saissetia oleae, cabbage aphid Brevicoryne brassicae, Lipaphis erysimi, citrus red scale Aonidiella aurantii, yellow scale Aonidiella citrine, citrus mealybug Planococcus citri, corn leaf aphid Rhopalosiphum maidis, aphid Aphis gossypii, jassid Amrasca biguttula biguttla, mealy bug Planococcus spp. And Pseudococcus spp., cotton stainer Dysdercus suturellus, whitefly Bemisia tabaci, cowpea aphid Aphis crassivora, grain aphid Sitobion avenae, golden glow aphid Uroleucon spp., grape mealybug Pseudococcus maritimus, green peach aphid Myzus persicae, greenhouse whitefly Trialeurodes vaporariorum, papaya mealy bug Pracoccus marginatus, pea aphid Acyrthosiphon pisum, sugarcane mealybug Saccharicoccus sacchari, potato aphid Myzus persicae, potato leaf hopper Empoasca fabae, cotton whitefly Bemisia tabaci, tarnished plant bug Lygus lineolaris, wooly apple aphid Eriosoma lanigerum, mango hopper Amritodus atkinsoni, Idioscopus spp.; order Lepidoptera, army worm Mythimna unipuncta, asiatic rice borer Chilo suppressalis, bean pod borer Maruca vitrata, beet armyworm Spodoptera exigua, black cutworm Agrotis ipsilon, bollworm Helicoverpa armigera , cabbage looper Trichoplusia ni, codling moth Cydia pomonella, croton caterpillar Achea janata, diamond backmoth Plutella xylostella, cabbage worm Pieris rapae, pink bollworm Pectinophora gossypiella, sugarcane borer Diatraea saccharalis, sugarcane early shoot borer Chilo infuscatellus tobacco budworm Heliothis virescens, tomato fruitworm Helicoverpa zea, velvet bean caterpillar Anticarsia gemmatalis, yellow stem borer Scirpophaga incertulas, spotted bollworm Earias vittella, rice leaffolder Cnaphalocrocis medinalis, pink stem borer Sesamia spp., tobacco leafeating caterpillar Spodoptera litura; brinjal fruit and shoot borer Leucinodes orbonalis, bean pod borer Maruca vitrata, Maruca testulalis, armyworm Mythimna separata, cotton pinkbollworm Pectinophora gossypiella, citrus leafminer Phyllocnistis citrella, cabbage butterfly Pieris bras-sicae, diamond backmoth Plutella xylostella, paddy stem borer Scirpophaga excerptallis, Scirpophaga incertulas, Scirpophaga innotata, wheat stem borer Sesamia inferens, Sitotroga cerealella, Spilosoma obliqua, fall armyworm Spodoptera frugiperda, Spodoptera littoralis, Spodoptera litura, Trichoplusia ni, Tryporyza nivella, Tryporyza incertulas, Tuta absoluta; from the order Coleoptera, for example, apple twig borer Amphicerus spp., corn root worm Diabrotica virgifera, cucumber beetle diabrotica balteata, boll weevil Anthonomus grandis, grape flea beetle Altica chalybea, grape root worm Fidia viticola, grape trunk borer Clytoleptus albofasciatus, radish flea beetle Phyllotreta armoraciae, maize weevil Sitophilus zeamais, northern corn rootworm Diabrotica barberi, rice water weevil Lissorhoptrus oryzophilus, Anthonomus grandis, Bruchus lentis, Diabrotica semipunctata, Diabrotica virgifera, Dicladispa armigera, Epila-chna varivestis, various species of white grubs are Holotrichia bicolor, Holotrichia consanguinea, Holotrichia serrata, Leptinotarsa decemlineata, Phyllotreta chrysocephala, Popillia japonica etc; from the order Orthoptera, for example, Gryllotalpa spp., Locusta spp., and Schistocerca is spp.; from the order Thysanoptera, for example, Frankliniella spp., Thrips palmi, Thrips tabaci and Scirtothrips dorsalis; termites (Isoptera), e.g. Calotermes flavicollis, Coptotermes formosanus, Heterotermes aureus, Leucotermes flavipes, Microtermes obesi, Odontotermes obesus, Reticulitermes flavipes, Termes natalensis; from the order Heteroptera, for example, Dysdercus spp., Leptocorisa spp., from the order Hymenoptera, for example, Solenopsis spp. ; from the order Diptera, for example, Antherigona soccata, Dacus spp., Liriomyza spp., Melanagromyza spp.
The plant parasitic mites from the order Acarina, for example, Aceria mangiferae, Brevipalpus spp., Eriophyes spp., Oligonychus mangiferus, Oligonychus punicae, Panonychus citri, Panonychus ulmi, Polyphagotarsonemus latus, Tarsonemus spp., Tetranychus urticae, Tetranychus cinnabarinus.
The present invention has been described with reference to specific embodiment which is merely illustrative and not intended to limit the scope of the invention as defined in the present complete specification.

,CLAIMS:FORM 2
THE PATENTS ACT 1970
(39 of 1970)
&
The Patents Rules, 2003
COMPLETE SPECIFICATION
(See section 10 and rule 13)
1. TITLE OF THE INVENTION: “A Synergistic Ternary Insecticidal Composition”
2. APPLICANT:
(a) Name : RAJDHANI PETROCHEMICALS PRIVATE LIMITED
(b) Nationality : INDIAN
(c) Address : 6, LALITA COMPLEX, RASALA ROAD, NAVRANGPURA, AHMEDABAD-380009 Gujarat, India
PROVISIONAL
The following specification describes the invention. þCOMPLETE
The following specification particularly describes the invention and the manner in which it is to be performed.

FIELD OF INVENTION
The present invention relates to a synergistic ternary insecticidal composition. More specifically, the present invention relates to a synergistic ternary insecticidal composition comprising N’-tert-butyl-N’-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide, 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-N -[(Z)-methoxyiminomethyl]-2-methylbenzamide, and at least one compound selected from the group of insecticide; and a process of preparing said composition. The present invention further relates to an insecticidal composition that provides an effective control of insect pests and mites, increases plant tolerance against abiotic stress and improves overall health and vigor of the treated plant.

BACKGROUND OF THE INVENTION
In recent years, due to single drug use and unscientific drug use, many pests have become resistant to the currently used insecticides which have become a major problem in chemical control. At the same time, frequent application of insecticides has increased the burden on farmers and increased environmental pollution. Therefore, a new composition of high-efficiency, low-toxicity and environmentally-friendly insecticides has become a mainstream direction in the field of insecticides research. However, insecticides with different action mechanisms can be mixed reasonably according to a certain proportion, which can improve the efficacy against insect pests and mites, reduce the dosage, fewer residues, reduce environmental pollution, and effectively reduce the drug resistance of crops.
The reduction in effectiveness of insecticides due to the development of resistance is one of the forces that drives the discovery and development of new insecticides. Predicting whether or not a resistance mechanism that has conferred resistance to an existing insecticide will confer resistance to a novel insecticide is not necessarily a simple matter.
WO 2023199360A1 patent relates to pesticidal composition comprising bioactive amounts of fluxametamide, one insecticide selected from diamide group, at least one of compound from insecticides, fungicides or plant health additives and exicipients; and process of preparation thereof. The said patent application is concerned with increase plant tolerance against insect pests.
WO2012121121A1 patent relates to pest controlling compound and pest control method. A pest control composition containing: the quinoline compound; at least one hydrazide compound selected from group (A) consisting of chromafenozide, methoxyfenozide, and tebufenozide; and at least one insect/pest control compound selected from group (B) consisting of dinotefuran, ethiprole, thiamethoxam, permethrin, clothianidin, and nitenpyram. Method for controlling pests generally applied to cultivated plants of rice or rice fields.
This above mentioned inventions features binary composition. In contrast, the present invention contains ternary composition which broadens the spectrum of control and improves overall health of plants. The active ingredients known from the literature have certain disadvantages such as insufficient control efficacy, restriction of its use due to the appearance of drug-resistant insects or pests, phytotoxicity and contamination to plants, or toxicity to human beings, beasts, fishes and the like. Hence, there is a long felt need to develop novel and effective insecticidal combinations for controlling the harmful pests in plants that demonstrate high efficacy, are environmentally safe and can be advantageously formulated.
The insecticides currently in use are not that effective; and due to their prolonged indiscriminate and non-judicious use, some pests have developed resistance to such commonly used insecticides. Their use is thereby becoming increasingly difficult.
Therefore, there is an urgent need to develop new compositions, effective methods and formulations for controlling these harmful pests. At last, there is a need to provide an insecticidal composition which overcomes some of the existing problems and can be prepared easily without much complex manufacturing process. The present inventors have surprisingly developed an effective insecticidal combination which ameliorates the aforesaid shortcomings of the prior art.

OBJECT OF THE INVENTION
The principal object of the present invention is to provide a synergistic ternary insecticidal composition.
Another object of the present invention is to provide a synergistic ternary insecticidal composition comprising bioactive amounts of N’-tert-butyl-N’-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide, 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-N-[(Z)-methoxyiminomethyl]-2-methylbenzamide, at least one insecticide and agrochemically acceptable excipients; and method of preparation thereof.
Further object of the present invention is to provide insecticidal composition demonstrating high efficacy.
Yet another object of the present invention is to provide insecticidal composition for controlling the harmful pests in plants and to provide complete protection to crop plants against insect-pests and mites.
Still another object of the present invention is to provide insecticidal composition increasing plant tolerance against abiotic stress.
Further object of the present invention is to provide insecticidal composition to delay resistance development through engaging multiple modes of action or for insect pests and mite resistance management.
Another object of the present invention is to provide a method of preparing a stable and non-phytotoxic formulation which improves overall health, yield and vigor of the treated plant.
Further object of the present invention is to provide insecticidal composition which is environmentally safe.

SUMMARY OF THE INVENTION
The present invention provides a synergistic ternary insecticidal composition. More particularly comprising bioactive amounts of (A) N’-tert-butyl-N’-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide (B) 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-N-[(Z) -methoxyiminomethyl]-2-methylbenzamide; (C) at least one compound selected from the group of insecticides; and agrochemically acceptable excipients.
The formulation for an insecticidal composition is selected from Capsule suspension (CS), Dispersible concentrate (DC), Emulsifiable concentrate (EC), Emulsion, water in oil (EO), Emulsion, oil in water (EW), Micro-emulsion (ME), Oil dispersion (OD), Oil miscible flowable concentrate (oil miscible suspension (OF), Oil miscible liquid (OL), Suspension concentrate (SC), Suspo-emulsion (SE), Soluble concentrate (SL), Water dispersible granule (WG or WDG), Water soluble granule (SG), Water soluble powder (SP), Wettable powder (WP), A mixed formulation of CS and SC (ZC), A mixed formulation of CS and SE (ZE), a mixed formulation of CS and EW (ZW), Granule (GR) for soil application includes controlled release granules (CR), Jambo balls or bags (bags in water soluble pouch).
The process for preparing the present insecticidal composition can be modified accordingly by any person skilled in the art based on the knowledge of the manufacturing the formulation. However, all such variation and modification is still covered by the scope of present invention.
The present invention is formulated to control harmful insect pests and mites in plants demonstrating high efficacy and providing resistance management or to delay resistance development through engaging multiple modes of action. Further, the insecticidal composition is effective on crops which have been rendered tolerant to herbicides or class of herbicides. Moreover, it also showcases its synergistic efficacy on the crops rendering resistant towards harmful insects by genetic engineering methods. Therefore, the insecticidal composition results in an increase in plant tolerance against insect-pests and mites, abiotic stress and improve overall health and vigor of the treated plant making it environment friendly and demonstrating high efficacy.
DETAILED DESCRIPTION OF THE INVENTION
Before explaining the present invention in detail, it is to be understood that the invention is not limited in its application to the details of the parts illustrated. The invention is capable of other embodiments, as described above and of being practiced or carried out in a variety of ways. It is to be understood that the phraseology and terminology employed herein is for the purpose of description and not to limitation. The invention may have various embodiments and they may be performed as described in the following pages of the complete specification.
The terms and words used in the following description are not limited to the bibliographical meanings, but, are merely used by the inventors to enable a clear and consistent understanding of the invention. Accordingly, it should be apparent to those skilled in the art that the following description of exemplary embodiments of the present invention are provided for illustration purpose only and not for the purpose of limiting the scope of the invention.
It is to be understood that the singular forms "a," "an," and "the" include plural reference unless the context clearly dictates otherwise.
Features that are described and/or illustrated with respect to one embodiment may be used in the same way or in a similar way in one or more other embodiments and/or in combination with or instead of the features of the other embodiments.
It should be emphasized that the term "comprises/comprising" when used in this specification is taken to specify the presence of stated features, steps or components but does not preclude the presence or addition of one or more other features, steps, components or groups thereof.
The term 'plants' as used herein, refers to all physical parts of a plant, including seeds, seedlings, saplings, roots, tubers, stems, stalks, foliage and fruits. The term "plant" is to be understood as including wild type plants and plants, which have been modified by either conventional breeding, or mutagenesis or genetic engineering, or by a combination thereof.
The term "crop" refers to both, growing and harvested crops.
The term "insects" as used herein, includes all organisms in the class "Insecta."
The term "animal pest" includes arthropods, gastropods, and nematodes. Preferred animal pests according to the invention are arthropods, preferably insects and arachnids, in particular insects. Insects, which are of particular relevance for crops, are typically referred to as crop insect pests.
The term "insecticidal" as used herein, refers to the ability of an insecticide to increase mortality or inhibit growth rate of insects.
To "control" or "controlling" pests means to inhibit, through a toxic effect, the ability of pests to survive, grow, feed, and/or reproduce, or to limit pest related damage or loss in crop plants. To "control" pests may or may not mean killing the pests, although it preferably means killing the pests.
The term "health of a plant" or "plant health" is defined as a condition of the plant and/or its products. As a result of the improved health, yield, plant vigor, quality and tolerance to abiotic or biotic stress are increased.
"Yield" is to be understood as any plant product of economic value that is produced by the plant such as grains, fruits in the proper sense, vegetables, nuts, grains, seeds, wood (e.g. in the case of silviculture plants) or even flowers (e.g. in the case of gardening plants, ornamentals).
"Increased yield" of a plant, in particular of an agricultural, silvicultural and/or horticultural plant means that the yield of a product of the respective plant is increased by a measurable amount over the yield of the same product of the plant produced under the same conditions, but without the application of the composition according to the invention.
The present invention provides an insecticidal composition comprising
1. Compound A - N’-tert-butyl-N’-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide,
2. Compound B - 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-N-[(Z)-methoxyiminomethyl]-2-methylbenzamide,
3. Compound C - at least one compound selected from group of insecticides with the following mass percentage of the composition.
Sr. No. Ingredient Concentration range (w/w %)
1. Compound A 10 to 50
2. Compound B 1 to 20
3. Compound C 1 to 30
Compound A is methoxyfenozide, N’-tert-butyl-N’-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide is a benzoyl hydrazine low-toxic insecticide with high selective insecticidal activity against lepidopteran pests.

Compound A is mainly focused on contact-killing and has a certain systemic action, strong selectivity and has good control effect on lepidopteran pests such as cotton bollworm, cabbage caterpillar and diamondback moth, and is suitable for controlling human, animal and environmental safety, and is suitable for controlling vegetables, tea trees, fruit trees, ornamental plants and rice.
Compound B is fluxametamide, 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-N -[(Z)-methoxyiminomethyl]-2-methylbenzamide is a novel wide-spectrum insecticide that was discovered and synthesized by Nissan Chemical Industries, Ltd. It belongs to a class of compounds called isoxazolines, which are potent inhibitors of ?-aminobutyric acid (GABA)-, glutamate-, and glycine-gated chloride channels in insects.

Compound C is a wide-spectrum insecticide effective against a broad spectrum of pests. It is mainly used in the control of lepidopteran pests, thrips, whiteflies, leaf miners, beetles and mites on crops such as fruit trees, vegetables, soybeans, cotton and tea trees and other crops.
Insecticide(s) for Compound C is selected from but not limited to,

from the class of organophosphates (AChE-acetylcholine esterase inhibitors),

from the class of phenylpyrazoles-fiproles (GABA-gated chloride channel blockers) ,

from the class of pyrethroids (sodium channel modulators),

from the class of nicotinic insecticides (nicotinic acetylcholine receptor (nAChR) competitive modulators),

from the class of nereis toxin analogues (nicotinic acetylcholine receptor (nAChR) channel blockers),

from the class of spinosyns (nicotinic acetylcholine receptor (nAChR) allosteric modulators-Site I) ,

from the class of avermectins and milbemycins (glutamate-gated chloride channel (GluCl) allosteric modulators),

from the class of juvenile hormone mimics,

from the class of chordotonal organs modulators,

from the class of mite growth inhibitors affecting CHS1,

from the class of benzoylureas (inhibitors of the chitin biosynthesis affecting CHS1 ,

from the class of buprofezin (inhibitors of the chitin biosynthesis type 1),
from the class of cyromazine (moulting disruptors for dipteran),

from the class of microbial disruptors of insect midgut membrane,

from the class of uncouplers of oxidative phosphorylation,

from the class of octopamin receptor agonists: amitraz; from the class of inhibitors of mitochondrial ATP synthase,

from the class of METI (mitochondrial complex I) inhibitors,

from the class of METI (mitochondrial complex II) inhibitors,

from the class of METI (mitochondrial complex III) inhibitors,

from the class of METI (mitochondrial complex IV) inhibitors,

from the class of voltage-dependent sodium channel blockers,

from the class of inhibitors of the lipid synthesis, inhibitors of acetyl CoA carboxylase,

from the class of baculoviruses,

from the class of calcium activated potassium channel (KCa2) modulators and compounds of unknown or uncertain mode of action.

Compound C is selected from group consisting of

C1 acetamiprid, N-[(6-chloropyridin-3-ylmethyl-N’-cyano-N-methylemethanimidamide,

C2 clothianidin, 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3-methyl-2-nitroguanidine,
C3 bifenthrin, (2-methyl-3-phenylphenyl)methyl (1R,3R)-3-[(Z)-2-chloro-3,3,3-trifluoroprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate,

C4 lambda cyhalothrin, [(R)-cyano-(3-phenoxyphenyl)methyl] (1S,3S)-3-[(Z)-2-chloro-3,3,3-trifluoroprop-1-enyl]-2,2-dimethylcyclopropane-1 -carboxylate,

C5 acephate, N-[methoxy (methylsulfanyl)phosphoryl]acetamide,

C6 profenofos, 4-bromo-2-chloro-1-[ethoxy(propylsulfanyl)phosphoryl]oxybenzene,

C7 thiocyclam hydrogen oxalate, N,N-dimethyltrithian-5-amine;oxalic acid,

C8 cartap hydrochloride, S-[3-carbamoylsulfanyl-2-(dimethylamino)propyl] carbamothioate,

C9 spinosad, mixture of 50–95% (2R,3aS,5aR,5bS,9S,13S,14R,16aS,16bR)-2-[(6-deoxy-2,3,4-tri-O-methyl-a-L -mannopyranosyl)oxy]-13-{[4-(dimethylamino)-2,3,4,6-tetradeoxy-ß- D erythropyranosyl]oxy}-9- ethyl-2,3,3a,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b hexadecahydro-14-methyl-1H-as-indaceno[3,2-d]oxacyclododecine-7,15 dione and 50–5% (2S,3aR,5aS,5bS,9S,13S,14R,16aS,16bS)-2-[(6-deoxy-2,3,4-tri-O-methyl-a-L-mannopyranosyl)oxy]-13-{[4-(dimethylamino)-2,3,4,6 tetradeoxy-ß-D-erythropyranosyl]oxy}-9-ethyl 2,3,3a,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-hexadecahydro-4,14-dimethyl-1H-as-indaceno[3,2-d]oxacyclododecine-7,15 –dione,

C10 spinetoram, (2R,5R,9R,10S,14R,15S,19S)-15-[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy-7-[(2R,3R,4R,5S,6S)-4-ethoxy-3,5 -dimethoxy-6-methyloxan-2-yl]oxy-19-ethyl-14-methyl-20 oxatetracyclo [10.10.0.0.0]docos-11-ene-13,21-dione,
C11 emamectin benzoate, (1'R,2R,3S,4'S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-2-[(2S)-butan-2 -yl]-21',24'-dihydroxy-12'-[(2R,4S,5S,6S)-4-methoxy-5-[(2S,4S,5S,6S)-4 -methoxy-6-methyl-5-(methylamino)oxan-2-yl]oxy-6-methyloxan-2-yl]oxy -3,11',13',22'-tetramethylspiro[2,3-dihydropyran-6,6'-3,7,19 -trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2'-one,

C12 novaluron, N-[[3-chloro-4-[1,1,2-trifluoro-2-(trifluoromethoxy)ethoxy]phenyl]carbamoyl]-2,6-difluorobenzamide,

C13 abamectin, 1'R,2R,3S,4'S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-2-butan-2-yl-21',24'-dihydroxy-12'-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-3,11',13',22' -tetramethylspiro[2,3-dihydropyran- 6,6'-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2' -one;(1'R,2R,3S,4'S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-21',24' -dihydroxy-12'-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6 -methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-3,11',13',22' -tetramethyl-2-propan-2-ylspiro[2,3-dihydropyran-6,6'-3,7,19 -trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2'-one,

C14 hexythiazox, (4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide,

C15 fenpyroximate, tert-butyl 4-[[(E)-(1,3-dimethyl-5 phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate,

C16 diafenthiuruon, 1-tert-butyl-3-[4-phenoxy-2,6-di(propan-2-yl)phenyl]thiourea,

C17 pyriproxyfen, 2-[1-(4-phenoxyphenoxy) propan-2-yloxy] pyridine and

C18 flonicamid, N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide.

The present invention optionally comprises agrochemically acceptable excipients including, but not limited to, dispersing agents, anti-freezing agent, anti-foam agent, wetting agents, suspension aid and carriers, anti-microbial agent, thickener, colorants, quick coating agent or sticking agents (also referred to as “stickers” or “binders”), polymers, disintegrating agent, oil additive, buffering agent, and solvents.
However, those skilled in the art will appreciate that it is possible to utilize additional agrochemically acceptable excipients without departing from the scope of the present invention. The agrochemically acceptable excipient can be in the range from 0.1% to 99% of the total weight of the composition.
The amount of a composition according to the invention to be applied, will depend on various factors, such as the subject of the treatment, such as, for example plants, soil or seeds; the type of treatment, such as, for example spraying, dusting or seed dressing; the purpose of the treatment, such as, for example prophylactic or therapeutic disease control; in case of disease control the type of fungi to be controlled or the application time. This amount of the combinations of the present invention to be applied can be readily deduced by a skilled agronomist.
The combination of the present invention is formulated in a manner which suits the specific application. The formulation is selected from Capsule suspension (CS), Dispersible concentrate (DC), Emulsifiable concentrate (EC), Emulsion, water in oil (EO), Emulsion, oil in water (EW), Micro-emulsion (ME), Oil dispersion (OD), Oil miscible flowable concentrate (oil miscible suspension (OF), Oil miscible liquid (OL), Suspension concentrate (SC), Suspo-emulsion (SE), Soluble concentrate (SL), Water dispersible granule (WG or WDG), Water soluble granule (SG), Water soluble powder (SP), Wettable powder (WP), A mixed formulation of CS and SC (ZC), A mixed formulation of CS and SE (ZE), a mixed formulation of CS and EW (ZW), Granule (GR) for soil application includes controlled release granules (CR), Jambo balls or bags (bags in water soluble pouch).
More particularly, the composition is selected from Oil dispersion (OD), Suspo Emulsion (SE), Suspension Concentrate (SC), Suspo-emulsion (SE), Water Dispersible Granule/ Wettable Granule (WG/WDG), Wettable powder (WP) and a mixed formulation of capsule suspension CS and SC (ZC).
The inactive excipients used in various formulations are as follows:

A. Lists of inactive excipients used in Oil dispersion (OD) formulation:

The Oil Dispersion formulation (OD) of the present invention comprises agrochemically acceptable excipients including, but not limited to, wetting agent(s), wetting-spreading-penetrating agent(s), emulsifying agent(s), dispersing agent(s), stabilizer(s), antifoaming agent(s), antifreezing agent(s), solvent(s), and rheology modifier.

The wetting agent of OD is selected from, but not limited to, ethylene oxide/propylene oxide block copolymer, polyarylphenyl ether phosphate, ethoxylated fatty alcohol, sodium dioctyl sulfosuccinate, sodium lauryl sulphate, sodium dodecyl benzene sulfonate, alkyldiphenyl sulfonates, sodium isopropyl naphthalene sulfonate, alkylnaphthalenesulfonate or mixture thereof.

The wetting-spreading-penetrating agent of OD is selected from, but not limited to, organosilicone surfactants, trisiloxane ethoxylate, polydimethylsiloxane, polyoxyethylene methyl polysiloxane, polyoxyalkylene methyl polysiloxane, polyether polymethyl siloxane copolymer, heptamethyl trisiloxane, polyalkyleneoxide modified heptamethyl trisiloxane, polyether modified polysiloxane, may or may not be in modified form, may be liquid or powder form or mixture thereof.

The emulsifying agent of OD is selected from, but not limited to, castor oil ethoxylates, alcohol ethoxylates, fatty acid ethoxylates, sorbitan ester ethoxylates, sulphosuccinate, calcium salts of dodecylbenzene sulphonate, alkylammonium salts of alkylbenzene sulphonate, alkylsulphosuccinate salts, ethylene oxide-propylene oxide block copolymers, ethoxylated alkylamines, ethoxylated alkyl phenols, polyoxyethylene sorbitan monolaurate, polyxyethylene sobitol hexaoleate, ethoxylated sorbiton ester or mixture thereof.

The dispersing agent of OD is selected from, but not limited to, alkyl sulfonates, alkyl benzene sulfonates, alkyl aryl sulfonates, alkylphenolalkoxylates, tristyrylphenol ethoxylates, natural or synthetic fatty ethoxylate alcohols, natural or synthetic fatty acid alkoxylates, natural or synthetic fatty alcohols alkoxylates, alkoxylated alcohols such as n-butyl alcohol poly glycol ether, block copolymers such as ethylene oxide-propylene oxide block copolymers, ethylene oxide-butylene oxide block copolymers, fatty acid-polyalkylene glycol condensates, polyamine-fatty acid condensates, polyester condensates, salts of polyolefin condensates, sodium ligno sulfonate, sodium ploycarboxylate, EO/PO based copolymer, phenol sulfonate, sodium methyl oleoyl taurate, styrene acrylic acid copolymer, propyleneoxide-ethyleneoxide-copolymer, polyethylene glycol 2,4,6-tristyrylphenyl ether, tristyrylphenol-polyglycolether-phosphate, tristyrylphenole with 16 moles EO, tristyrylphenol-polyglycolether-phosphate, oleyl-polyglycolether with ethylene oxide, tallow fattyamine polyethylene oxide, nonylphenol polyglycolether with 9-10 moles ethylene oxide, salts of polyolefin condensates, styrene acrylic polymer or mixture thereof.

The stabilizers of OD is selected from, but not limited to, hectorite clay, aluminium magnesium silicate, bentonite clay, silica, attapulgite clay or mixture thereof.

The antifoaming agent of OD is selected from, but not limited to,silicone oil, silicone compound, C10~C20 saturated fat acid compounds, C8~C10 aliphatic alcohols compound, silicone antifoam emulsion, dimethylsiloxane, polydimethyl siloxane, vegetable oil based antifoam, tallow based fatty acids, polyalkyleneoxide modified polydimethylsiloxane or mixture thereof.

The anti-freezing agent of OD is selected from, but not limited to, ethylene glycol, propane diols, glycerine, the urea, glycol monoethylene glycol, diethylene glycol, polypropylene glycol, polyethylene glycol, glycerine, urea, magnesium sulfate heptahydrate, sodium chloride, preservative-1,2-benzisothiazolin-3(2H)-one, sodium salt, sodium benzoate, 2-bromo-2-nitropropane-1,3-diol, formaldehyde, sodium o-phenylphenate, 5-chloro-2-methyl-4-isothiazolin-3-one, 2-methyl-4-isothiazolin-3-one or mixture thereof.

The solvent of OD is selected from, but not limited to, vegetable oil its alkylated orethoxylated or esterified form, the alkylated vegetable oil, methylated vegetable oil, ethylated vegetable oil, the vegetable oils include olive oil, kapok oil, castor oil, papaya oil, camellia oil, sesame oil, corn oil, rice bran oil, cotton seed oil, soybean oil, groundnut oil, rapeseed-mustard oil, linseed oil, tung oil, sunflower oil, safflower oil, coconut oil, the alkyl ester of vegetable oils, methyl ester, ethyl ester, propyl ester, butyl ester of vegetable oils, methylated seed oil, polyalkyleneoxide modified polydimethylsiloxane alkylphenol ethoxylate, rapeseed oil methyl ester, rapeseed oil ethyl ester, rapeseed oil propyl esters, rapeseed oil butyl esters, soybean oil methyl ester, soybean oil ethyl ester, soybean oil propyl ester, soybean oil butyl ester, castor oil methyl ester, castor oil ethyl ester, castor oil propyl ester, castor oil butyl ester, cotton seed oil methyl ester, cotton seed oil ethyl ester, cotton seed oil butyl ester, cotton seed oil propyl ester, tall oil fatty acids esters-tallow methyl ester, tallow ethyl ester, tallow propyl ester, bio-diesel, mineral oil, aromatic solvents, isoparaffin, base solvent, fatty acid amides, C1-C3 amines, alkylamines, alkanolamines with C6-C18 carboxylic acids, fatty acids, alkyl esters of fatty acids, methyl oleate, ethyl oleate, methyl soyate, ethyl soyate, alkyl benzenes, alkylnaphthalenes, polyalkylene glycol ethers, fatty acid diesters, fatty alkylamides, diamides, dialkylene carbonates, ketones, alcohols, cyclohexanone, acetophenone, NMP, dimethyl sulfoxide, benzyl alcohol, butanol, N-octanol, N-propanol, 2-ethyl hexanol, tetrahydro furfuryl alcohol, isophorone, fatty acid dimethyl amide, 2-hexylethyl lactate, propylene carbonate, methylated seed oil or mixture thereof.

The rheology modifier of OD is selected from, but not limited to bentonite clay.

Manufacturing process for Oil dispersion (OD) formulation:

Part A-Preparation of the liquid premix (OD)
Step 1: The vegetable oil or solvent or both are charged into a vessel with an anchor stirrer.
Step 2: The emulsifier(s) and dispersing agent(s) are added under stirring condition until all the ingredients get completely dissolved.

Part B-Preparation of the slurry (OD)
Step 1: The liquid premix is charged into a second vessel which is equipped with a cooling and heating device of a high shear stirrer.
Step 2: The active ingredients are added and homogenized thoroughly. The mixture is pre-milled and a particle size distribution is achieved by the final milling, practised along with a bead mill as required by the specification.

Part C-Preparation of the thickener gel (OD)
Step 1: The vegetable/plant/seed oil or solvent is charged to the vessel which is equipped with a high shear stirrer.
Step 2: The thickener(s) is/are gradually added throughout by mixing and maintaining high-shear. The stirring is continued until thoroughly mixed.
Step 3: The thickener activating agent(s) is/are added under stirring condition. Further, the gel is allowed to get swell whilst maintaining the mixing.

Part D-Preparation of the final formulation (OD)
Step 1: The thickener gel is added and the mixture is dispersed by using a high shear stirrer.
Step 2: The recommended wetting and spreading agent(s) or adjuvant(s) (silicone or non-silicone based) are finally added to this formulation and dispersed by using high shear stirrer.
Step 3: The finished formulation is checked with specification.
Step 4: The material is packed in its required package sizes when approved.

B. Lists of inactive excipients used in Suspension Concentrate (SC) formulation:

The Suspension Concentrate formulation (SC) of the present invention comprises agrochemically acceptable excipients including, but not limited to, wetting agent(s), wetting-spreading-penetrating agent(s), dispersing agent(s), suspending agent(s), antifoaming agent(s), antifreezing agent(s), preservative(s), thickener(s) and humectants(s).

The wetting agent of SC is selected from, but not limited to, ethylene oxide/propylene oxide (EO/PO) block copolymer, polyarylphenyl ether phosphate, polyalkoxylated butyl ether, ethoxylated fatty alcohol, sodium dioctyl sulfosuccinate, sodium lauryl sulfate, sodium dodecyl benzene sulfonate, alkyl diphenyl sulfonates, sodium isopropyl naphthalene sulfonate, alkyl naphthalene sulfonate, ethoxylated alcohol, natural fatty alcohol, lauryl alcohol ethoxylate, lauryl alcohol alkoxylate, synthetic alcohol ethoxylate, tridecyl alcohol ethoxylate, 2-ethyl hexanol, 2-propylheptanol, isodecyl alcohol or mixture thereof.

The wetting-spreading-penetrating agent of SC is selected from, but not limited to, methylated seed oil, polyakyleneoxide modified trisiloxane, trisiloxane ethoxylate, heptamethyl trisiloxane, modified polyalkyleneoxide, modified heptamethyl trisiloxane, polyether modified polysiloxane, polyalkyleneoxide modified trisiloxane, polyalkyleneoxide modified polydimethylsiloxane, liquid or powder form or mixture thereof.

The dispersing agent of SC is selected from, but not limited to, ethylene-propylene oxide block coplolymer, naphthalenesulfonic acid, sodium salt condensate with formaldehyde, alkylated naphthalene sulfonate, sodium salt, sodium salt of naphthalene sulfonate condensate, sodium ligno sulfonate, sodium polycarboxylate, EO/PO based copolymer, phenol sulfonate, sodium methyl oleoyl taurate, styrene acrylic acid copolymer, propylene oxide-ethylene oxide-copolymer, polyethylene glycol 2,4,6-tristyrylphenyl ether, tristyrylphenol-polyglycol ether-phosphate, tristyrylphenole with 16 moles EO, tristyrylphenol-polyglycol ether-phosphate, oleyl-polyglycol ether with ethylene oxide, tallow fatty amine polyethylene oxide, nonylphenol polyglycol ether with 9-10 moles ethylene oxide, sodium naphthalene sulphonate formaldehyde condensates or mixture thereof.

The suspending agent of SC is selected from, but not limited to, aluminum magnesium silicate, bentonite clay, silica, attapulgite clay or mixture thereof.

The antifoaming agent of SC is selected from, but not limited to, silicone antifoam emulsion, dimethyl siloxane, polydimethylsiloxane, vegetable oil based antifoam, tallow based fatty acids or mixture thereof.

The anti-freezing agent of SC is selected from ethylene glycol, propane diols, glycerin or the urea, glycol, monoethylene glycol, diethylene glycol, polypropylene glycol, polyethylene glycol, glycerin, urea, magnesium sulfate heptahydrate, sodium chloride or mixture thereof.

The preservatives of SC is selected from, but not limited to, 1,2-benzisothiazolin-3(2H)-one, sodium salt, sodium benzoate, 2-bromo-2-nitropropane-1,3-diol, formaldehyde, sodium o-phenyl phenate, 5-chloro-2-methyl-4-isothiazolin-3-one, 2-methyl-4-isothiazolin-3-one or mixture thereof.

The thickeners of SC is selected from, but not limited to, xanthan gum, PVK, carboxymethyl celluloses, polyvinyl alcohols, gelatin, sodium carboxymethylcellulose, hydroxyethyl cellulose, sodium polyacrylate, modified starch, acacia gum or mixture thereof.

The humectants of SC is selected from, but not limited to, urea, humic acid, glycerol, lactose or mixture thereof.

Manufacturing process for Suspension Concentrate (SC) formulation:

Step 1: Gel preparation: A required quantity of water is charged to a vessel which is equipped with a high shear stirrer whilst the agitation is initiated. A required amount of preservative(s) is/are added and mixed to form a homogenous mixture. A required amount of thickener(s) is/are added and mixed vigorously to achieve wetness.

Step 2: A required quantity of water is charged to a vessel which is equipped with a bulk agitator and a high shear homogenizer; initiated the agitation. Further, a required amount of an anti freezing agent(s) is/are added and mixed to achieve uniformity. Moreover, the antifoaming agent(s) is/are added whilst ensuring that it is well dispersed. The wetting and dispersing agent(s) is/are added and mixed to achieve uniformity whilst ensuring that the dispersing agent(s) is/are fully dispersed.

Step 3: The active ingredients are added and the agitation of the vessel contents are continued until all the compounds get dissolved. The pre-mix is milled through a colloid mill and subsequently through a dyno mill to meet the specified particle size.

Step 4: The remaining antifoaming agent(s) is/are added to this SC mill base to a vessel which is equipped with the bulk agitator and mixed to achieve uniformity. The required amount of 2% aqueous pre-gel and suspending agent(s) is/are added and the agitation is continued until the formulation is homogeneous and has reached the target viscosity.

Step 5: The final product is submitted for QC’s approval.

Step 6: The material is packed in its required package sizes when received approval.

C. Lists of inactive excipient used in Suspo Emulsion (SE) formulation [mixed formulation of SC+EC]:

The Suspo Emulsion formulation (SE) is a mixture of Suspension Concentrates (SC) and Emulsifiable Concentrate (EC). The Suspo Emulsion
(SE) of the present invention comprises agrochemically acceptable excipients including, but not limited to, solvent(s), emulsifier(s), stabilizer(s), antifreezing agent(s), antifoaming agent(s), suspending agent(s), wetting agent(s), wetting-spreading-penetrating agent(s), preservative(s), thickener(s), dispersing agent(s), buffering agent(s) and humectants(s). Since the excipients for SC are the same, only the excipients for SE are listed here.

The solvent of SE is selected from, but not limited to, water, water soluble alcohols and dihydroxy alcohol ethers, water soluble alcohol or lower alcohol -1 to 4 carbon atoms, methanol, ethanol, n-propanol, isopropanol, n-butanol, tert-butanol, macromolecular alcohol, polyethylene glycol, sorbitol, glucitol, dihydroxy alcohol ethers, dihydroxy alcohol alkyl ether, dihydroxy alcohol aryl ethers, dihydroxy alcohol alkyl ether, ethylene glycol methyl ether, diethylene glycol methyl ether, propylene glycol methyl ether, di-propylene glycol methyl ether, ethylene glycol ethyl ether, diethylene glycol ethyl ether, propylene glycol ethyl ether, di-propylene glycol ethyl ether, dihydroxy alcohol aryl ethers includes ethylene glycol phenyl ether, diethylene glycol phenyl ether, propylene glycol phenyl ether, di-propylene glycolphenyl ether, aromatic solvent C-9 or in combination thereof.
Hyrdocarbons, n-pentane, hexane(s), cyclohexane, methylcyclohexane, heptane, isooctane, benzene, toluene, xylene(s), isophorone, ester solvents, methyloleate, dimethylamide, morpholineamide derivatives of C6-C16 fatty acids, mono-alkylene carbonates, ethylene carbonate, propylene carbonate, butylene carbonates, dimethylsulfoxide (DMSO), 2-ethylhexanol, n-butanol, n-alkylpyrrolidones, fatty acid dimethyl esters, fatty acid esters, dibasic esters, aromatic hydrocarbons, aliphatic hydrocarbons, one or more dimethylamides, C8-dimethylamide, C10-dimethylamide, C12-dimethylamide, ethylene glycol, propylene glycol, polyalkylene glycols, aromatic hydrocarbons, methylpyrrolidinone (NMP), dimethylformamide (DMF), dimethylisosorbide (DMI), isophorone, acetophenone, 1,3-dimethyl-2-imidazolidonone, lactate esters, dimethyl, diethylcarbonates, alcohols including methanol, ethanol, iso-propanol, n-propanol, n-butanol, iso-butanol, tert-butanol, methyl L-lactate, 2-ethylhexyl L-lactate, ethyl L-lactate, n-butyl L-lactate, octyl phenol ethoxylates or mixture thereof.

The emulsifier of SE is selected from, but not limited to, salts of dodecylbenzene sulphonate, Ca-salts, amine salts, sulphonates of other C11-C16 alkylbenzenes, alkylether sulphates, alkylphenoletherphosphates, ester phosphates, non-ionic surfactants, alkoxylated alcohols, alkylphenols, ethoxylated fatty acids, ethoxylated vegetable oils, ethoxylated castor oil, fatty acid esters, sorbitol, their ethoxylated derivatives, ethoxylated amines, condensates of glycerol, catanionic emulsifiers, cationic amine, alkylsulphonate, ether sulphonate, ether phosphate, alkoxylated alcohols, alkoxylated alkylphenols, ethoxylated fatty acids, ethoxylated vegetable oils, ethoxylated tristyrylphenol-tristyrlphenol with 16 moles EO, tristyrylphenol-polyglycolether-phosphate, fatty acid esters of sorbitol, ethoxylated derivatives thereof, ethoxylated amines, condensates of glycerol, sulfonated alkylbenzenes in the range C11-C16, salts thereof, alkylether sulphates, alkyletherphosphates, alkylphenoletherphosphates, salts of phosphate esters of ethoxylated tristyrylphenol, salts of sulphated ethers of ethoxylated tristyrylphenol, catanionic system, alkylsulphonate, alkylethersulphonate, ether sulphate, ether phosphate, alkyletherphosphate, nonylphenol polyethoxyethanols, castor oil polyglycol ethers, poly adducts of ethylene oxide and polypropylene, tributyl phenoxy polyethoxy ethanol, octyl phenoxy polyethoxy ethano, polyarylphenyl anionic ether sulphate, ammonium salts or mixture thereof.

The stabilizer of SE is selected from, but not limited to, butylated hydroxytoluene (BHT) and epoxidized soybean oil (ESBO), epichlorhydrin or mixture thereof.

The buffering agent of SE is selected from, but not limited to, calcium hydroxyapatite, potassium dihydrogen phosphate, sodium hydroxide, carbonated apatite, calcium carbonate, sodium bicarbonate, tricalcium phosphate, calcium phosphates, carbonated calcium phosphates, amine monomers, lactate dehydrogenase, magnesium hydroxide, citric acid or mixture thereof.

Manufacturing process for Suspo Emulsion (SE) formulation:

Step 1: Gel preparation: A required quantity of water is charged to a vessel which is equipped with a high shear stirrer whilst the agitation is initiated. The required amount of preservative(s) is/are added and mixed to achieve homogeneity. Further, a required amount of thickener(s) is/are added and mixed vigorously to achieve full wetness.

Step 2: Oil phase: The solvent(s) is/are charged into the vessel and then the active is slowly added and if required, it is heated for 50°C so that the active ingredients can be dissolved in the solvent and followed by addition of emulsifier(s).

Step 3: The agitation is initiated when a required quantity of water is charged to a vessel which is equipped with a bulk agitator and a high shear homogenizer. A required amount of anti freezing agent(s) is/are added and mixed to achieve a uniform mixture. The antifoaming agent(s) is/are added and ensured that it is well dispersed. The wetting and dispersing agent(s) is/are added and mixed to achieve uniform mixture and ensured that the dispersing agent is fully dispersed.

Step 4: The active ingredients are added in the vessel and agitated till entire compounds get dissolved. The pre-mix is milled through a colloid mill and subsequently through a dyno mill to achieve a specified particle size.

Step 5: The remaining antifoaming agent(s) is/are added in the mill base to a vessel which is equipped with bulk agitator and mixed to achieve uniformity.

Step 6: An addition of an oil phase in an aqueous phase is performed and stirred for 30 minutes by using homogenizer.

Step 7: A required amount of aqueous pre-gel and suspending agent(s) are added. A homogenous mixture and a target viscosity are achieved by continuous agitation.

Step 8: The final product is submitted for QC’s approval.

Step 9: The material is packed in its required package sizes when approved.

D. Lists of inactive excipient used in WG (Wettable Granule)/WDG (Water Dispersible Granule) formulation:

The wettable granule/ water dispersible granule formulation (WG/WDG) of the present invention comprises agrochemically acceptable excipients including, but not limited to, dispersing agent(s), wetting agent(s), antifoaming agent(s), carrier(s), disintegrating agent(s) and humectants(s).

The dispersing agents of WG/WDG is selected from, but not limited to, alkylnaphthalene sulfonate sodium salt, alkylnaphthalene sulfonate, modified polyacrylate copolymer, sodium polycarboxylate, naphthalenesulfonic acid, sodium salt condensates with formaldehyde, polyalcoxylated alkylphenol, naphthalenesulfonic acid formaldehyde condensate, methylnaphthalene-formaldehyde-condensate sodium salt, naphthalene condensates, lignosulfonates, polyacrylates, phosphate esters, calcium lignosulfonate, lignin sulfonate sodium salt or mixture thereof.

The wetting agents of WG/WDG is selected from, but not limited to, sodium N-methyl-N-oleoyl taurate, alkylated naphthalene sulfonate, sodium salt, mixture of isomers of dibutylnaphthalene sulphonic acid sodium salt, sodium di-isopropylnaphthalenesulphonate, sodium isopropyl naphthalene sulphonate, sodium lauryl sulfate, dioctyl sulfate, alkyl naphthalene sulfonates, phosphate esters, sulphosuccinates, non-ionic, tridecyl alcohol ethoxylate, alkyl-alkaryl sulfonates such as alkylbenzene sulfonates, alpha olefin sulfonate, alkyl naphthalene sulfonates, ethoxylated, non-ethoxylated alkyl, alkaryl carboxylates, alkyl, alkaryl phosphate esters, alkyl polysaccharide, di, mono alkyl sulfosuccinate derivatives, alpha olefin sulfonates, alkyl naphthalene sulfonates, dialkyl sulphosuccinates, butyl, dibutyl, isopropyl, di-isopropyl naphthalene sulfonate salts, C12 alkyl benzene sulfonate or C10-C16 alkyl benzene sulfonate, organosilicons surfactants includes trisiloxane ethoxylate, polydimethylsiloxane, polyoxyethylene methyl polysiloxane, polyoxyalkylene methyl polysiloxane, polyether polymethyl siloxane copolymer, trisiloxaneheptamethyl, polyalkyleneoxide modified heptamethyl trisiloxane, polyether modified polysiloxane or mixture thereof.

The antifoaming agent of WG/WDG is selected from, but not limited to polydimethylsiloxane.

The carrier of WG/WDG is selected from, but not limited to, china clay, silica, lactose anhydrous, ammonium sulfate, sodium sulfate anhydrous, corn starch, urea, EDTA, urea formaldehyde resin, diatomaceous earth, kaolin, bentonite, kieselguhr, fuller's earth, attapulgite clay, bole, loess, talc, chalk, dolomite, limestone, lime, calcium carbonate, powdered magnesia, magnesium oxide, magnesium sulphate, sodium chloride, gypsum, calcium sulphate, pyrophyllite, silicates, silica gels, fertilizers, ammonium sulphate, ammonium phosphate, ammonium nitrate and urea, natural products of vegetable, grain meals, flours, bark meals, wood meals, nutshell meals, cellulosic powders, synthetic polymeric materials, ground-powdered plastics, resins, bentonites, zeolites, titanium dioxide, iron oxides, hydroxides, aluminium oxides, hydroxides, organic materials such as bagasse, charcoal, synthetic organic polymers or mixture thereof.

The disintegrating agent of WG/WDG is selected from, but not limited to, citric acid, succinic acid, sodium bicarbonate or mixture thereof.

The humectants of WG/WDG is selected from, but not limited to, urea, humic acid, glycerol, lactose or mixture thereof.

Manufacturing process for Wettable granule/ Water Dispersible Granule (WG/ WDG):

Step 1: An exact weight of active ingredients is considered and a required quantity of binder(s) and surfactant(s) is/are added in the blender and mixed to achieve a complete homogenization.

Step 2: The homogenized mixture is milled to achieve required wet sieve and post blended to attain homogeneity.

Step 3: The above described homogenous material is passed through an extruder for granulation to achieve granular of require size.

Step 4: The wet granules are transferred through fluidized bed drier to remove excess moisture.

Step 5: The wet granules are further transferred to vibro shifter and further graded using vibrator screens.

Step 6: The final material is collected from the vibro shifter into drum.

Step 7: The sample is sent to QC for an approval.

Step 8: The material is transferred into the different size of drums when received an approval from QC.

E. List of inactive excipients used in the ZC formulation [mixed formulation of CS+SC]:

The mixed formulation (ZC) is a mixture of Capsule Suspension (CS) and Suspension Concentrates (SC). The mixed formulation (ZC) of the present invention comprises agrochemically acceptable excipients including, but not limited to, wall forming material(s) 1, wall forming material(s) 2, dispersing agent(s), wetting agent(s), wetting-spreading-penetrating agent(s), solvent(s), thickner(s), suspending agent(s), antifoaming agent(s), antifreezing agent(s), preservative(s), emulsifier(s) and buffering agent(s). Since the excipients for SC are the same, only the excipients for CS are listed here.

The wall forming material 1 of ZC is selected from, but not limited to, tetramethylene diisocyanate, pentamethylene diisocyanate, hexamethylene diisocyanate, toluene diisocyanate, 4,4-diphenylmethenediisocyanate (MDI), polymethylene polyphenylene isocyanate, 2,4,4’-diphenyl ether tri-isocyanate, 3,3’-dimethyl-4,4’-diphenyl diisocyanate, 3,3’-dimethoxy-4,4’-diphenyl diisocyanate, 1,5-naphthylene diisocyanate, 4,4’4"-triphenylmethane tri-isocyanate, toluene diisocyanate, polymethylene polyphenylisocyanate, polyurethane comprising of polyfunctional isocyanate, a polyamine in polarized form or mixture thereof.

The wall forming material 2 of ZC is selected from, but not limited to, Diethylene triamine, Ammonia, hexamine, ethylenediamine, propylene-1,3-diamine, tetramethylenediamine, pentamethylenediamine, 1,6-hexamethylenediamine, diethylenetriamine, triethylenetetramine, tetraethylenepentamine, pentaethylenehexamine, 4,9-dioxadodecane-1, 12-diamine, 1,3-phenylenediamine, 2,4-toluenediamine, 2,6-toluenediamine, 4,4’-diaminodiphenylmethane, 1,3-phenylenediamine, 1,5-diaminonaphthalene, 1,3,5-triaminobenzene, 2,4,6-triaminotoluene, 1,3,6-triaminonaphthalene, 2,4,4'-triaminodiphenyl ether, 3,4,5-triamino-1,2,4-triazole, 1,4,5,8-tetraminoanthraquinone or mixture thereof.

The solvent of ZC is selected from, but not limited to, hydrocarbon solvent such as an aliphatic, cyclic, aromatic hydrocarbons, toluene, xylene, paraffin, tetrahydronaphthalene, alkylated naphthalene, their derivatives, mineral oil fractions of medium to high boiling point such as kerosene, diesel oil, coal tar oils, a vegetable oil such as corn oil, rapeseed oil, a fatty acid ester such as C1-C10-alkylester of a C10-C22-fatty acid, methyl-ethyl esters of vegetable oils such as rapeseed oil methyl ester, corn oil methyl ester, acetophenone, 2-heptanon, 3-heptanone, 2-hexanone, 5-methyl-2-hexanone , 5-methyl-3-heptanone, 3-methyl-2-hexanone, 4-methyl-2-hexanone, 2-methyl-3-hexanone, 4-methyl-3-hexanone, 5-methyl-3-hexanone, 3-ethyl-2-pentanone, 3,3-dimethyl-2-pentanone, 3,4-dimethyl-2-pentanone, 4,4-dimethyl-2-pentanone, 2,2-dimethyl-3-pentanone , 2,4-dimethyl-3-pentanone, 2-octanone, 2,5-dimethyl-3-hexanone, 2,2-dimethyl-3-hexanone, 3,3-dimethyl-2-hexanone, 3,4-dimethyl-2-hexanone, 4,4-dimethyl-3-hexanone, 3-ethyl-4-methyl-2-pentanone, 2-methyl-3-heptanone, 2-methyl-4-heptanone, 3-methyl-2-heptanone, 3-methyl-4-heptanone, 5-methyl-3-heptanone, 6-methyl-2-heptanone, 6-methyl-3-heptanone, 3-octanone, 4-octanone, 2,2,4-trimethyl-3-pentanone, 3-ethyl-3-methyl-2-pentanone, 5-methyl-2-heptanone, isoprene or mixture thereof.

The buffering agent of ZC is selected from, but not limited to, sodium hydroxide, potassium hydroxide, acetic acid, sulphuric acid, hydrochloric acid, ortho phosphoric acid, ammonium hydroxide or mixture thereof.

The emulsifier of ZC is selected from, but not limited to, alkylbenzene sulfonate calcium salts, tristyrlphenol polyethoxyester phosphate or mixture thereof.

Manufacturing process for mixed formulation ZC:

Step 1: The aqueous phase - Charged water is added to a stainless steel vessel equipped with a high speed stirrer. The wetting agent(s), dispersing agent(s) 1 and dispersing agent(s) 2 is/are added into the vessel under agitation followed by the addition of 50% quantity of antifoam to avoid foam generation in this vessel.

Step 2: The organic phase - Charged heavy aromatic hydrocarbons solvent is added into second stainless-steel reactor followed by the addition of melted active ingredient into the reactor slowly. Afterwards, the wall forming material(s) 1 is/are charged to the reactor while mixing it. At last, the contents of the reactor are cooled down to room temperature.

Step 3: The high shear disperser of aqueous phase is initiated and the ‘organic solution’ is charged into the ‘aqueous phase solution’ under gravity at a specific rate to achieve the required particle size followed by shearing for 30 min. Initiate the reactor to heat around 50°C by stirring the formulation under slow rpm for 3-4 hours for the completion of polymerization reaction.

Step 4: The wall forming material(s) 2 is/are added so that the residual wall forming material(s) 1 can be consumed. Stir the same for 1 hour at the same temperature. Upon requirement, half quantity of the antifoam can be added to remove foam generation caused due to CO2 during the reaction.

Step 5: Upon the completion of wall polymerization reaction, the agitator’s speed is increased. The remaining half quantity of the antifoam(s) is/are added to the formulation. The mixture is allowed to de-gas for approximately 30 minutes to remove CO2 from the solution under slight vacuum. The linear polysaccharide(s), preservative(s) and at last freezing agent(s) is/are added and mixed for few minutes. At last, buffering agent(s) is/are added for pH adjustment and mixed well.

Step 6: The final product is sent for the approval of QC.

Step 7: Upon the approval, the material is packed in its required pack sizes.

EXAMPLES
The present invention has been described with reference to specific embodiment which is merely illustrative and not intended to limit the scope of the invention as defined in the present complete specification.
Biological Examples:

The synergistic pesticide action of the inventive mixtures can be demonstrated by the experiments below. A synergistic effect exists wherever the action of a combination (ready-mix) or tank mix of active ingredient is greater than the sum of the action of each of the compounds alone. Therefore, a synergistically effective amount or an effective amount of a synergistic composition or combination is an amount that exhibits greater pesticide activity than the sum of the pesticide activities of the individual compounds.

In the field of agriculture, it is often understood that the term “synergy” is as defined by Colby S.R. in an article entitled “ Calculation of the synergistic and antagonistic responses of herbicide combinations” published in the journal Weeds, 1967, 15, p.20-22, incorporated herein by reference in its entirety. The action expected for a given combination of two or three active compounds can be calculated as follows:

The objective of the present studies was to study the synergism and benefits of present compositions.

Example 1: Pod borer larval control in chickpea.
Crop : Chickpea
Location : Chhindwara, Madhya Pradesh
Treatments : 12
Crop age : 75 days after sowing.
Spray water volume : 400 liters per hectare.
Method of Application: Foliar spray with battery operated knapsack sprayer fitted with hollow cone nozzle.

Observation Methods:
Pod borer (Helicoverpaarmigera) larval control (%): Count the number of live larvae per plant. Record observations from 10 plants per plot on 14th days after application.

Composition of Compound A 30% + Compound B 7% + Compound C1 8% WG [T1 of Ex. 1]
Chemical composition Function Percent (w/w)
Compound A a.i. Compound A 30.00
Compound B a.i. Compound B 7.00
Compound C1 a.i. Compound C 8.00
Alkyl naphthalene sulfonate Dispersing agent I 6.00
Modified polyacrylate copolymer Dispersing agent II 4.00
Sodium isopropyl naphthalene sulfonate Wetting agent 5.00

Polydimethylsiloxane Antifoaming Agent 1.00
Lactose anhydrous Carrier 15.00
China clay Carrier 24.00
Total 100.00
Active ingredient on 100% purity basis

Storage Stability: Composition of Compound A 30% + Compound B 7% + Compound C1 8% WG [T1 of Ex. 1]
Laboratory storage stability for 14 days [T1 of Ex. 1]
Parameters Specifications Initial At 54±2 °C At 0±2 °C
Compound A a.i. 29.10 to 31.50 31.36 31.30 31.36
Compound B a.i. 6.65 to 7.35 7.32 7.29 7.32
Compound C1 a.i. 7.60 to 8.40 8.36 8.34 8.36
Compound A suspensibility (%) 70 98.40 97.30 98.20
Compound B suspensibility (%) 70 98.20 97.50 98.20
Compound C1 suspensibility (%) 70 98.80 97.40 98.60
pH range (1% aq. Suspension) 5 to 9 7.50 7.60 7.50
Wettability Max 30 s 10.00 12.00 10.00
Wet Sieve(45 micron) Mini 98.5% 99.50 99.40 99.50
Bulk Density 0.45-0.85 0.50 0.50 0.50
Moisture Content Max 2.0% 1.40 1.20 1.40
Persistent foam ml (after 1 minute) max. 60 nil nil nil

Room temperature storage stability up to 12 months [T1 of Ex. 1]
Parameters Specifications 1 month 6 month 12 month
Compound A a.i. 19.4 to 21 31.36 31.36 31.30
Compound B a.i. 6.65 to 7.35 7.32 7.32 7.29
Compound C1 a.i. 7.6 to 8.4 8.36 8.36 8.34
Compound A suspensibility (%) 70 98.40 98.40 98.30
Compound B suspensibility (%) 70 98.20 98.10 98.10
Compound C1 suspensibility (%) 70 98.80 98.80 98.70
pH range (1% aq. Suspension) 5 to 9 7.50 7.50 7.55
Wettability Max 30 s 10.00 10.00 11.00
Wet Sieve(45 micron) Mini 98.5% 99.50 99.50 99.50
Bulk Density 0.45-0.85 0.50 0.50 0.50
Moisture Content Max 2.0% 1.40 1.40 1.30
Persistent foam ml (after 1 minute) max. 60 nil nil nil
The composition of Compound A 30%+Compound B 7%+Compound C1 8% WG meets the all inhouse specifications for storage stability studies in laboratory (at 54±2 °C and At 0±2 °C for 14 days) and room temperature (for 12 months)

Manufacturing process for 100 kg batch of Compound A 30%+Compound B 7%+Compound C1 8% WG [T1 of Ex. 1]

Step 1: china clay (24 kg), lactose anhydrous (15 kg), silicone antifoam (0.5 kg), sodium isopropyl naphthalene sulfonate (5 kg), alkyl naphthalene sulfonate (6 kg) and modified polyacrylate copolymer (4 kg) were charged into a premix blender and homogenized for 30 minutes.

Step 2: Compound A (30 kg), compound B (7 kg) and compound C1 (8 kg) were also charged and homogenized for 30 minutes and this pre-blended material was grinded through jet mill/ air classifier mills. Further, finely grinded material was blended in post blender till it became homogeneous. (For approx 1.5 hr)
Step 3: Finely grinded powder was mixed with water (12 kg) having silicone antifoam (0.5 kg) to form extrudable dough.

Step 4: The dough was passed through extruder to achieve granules of required size.

Step 5: Wet granules was passed through fluidized bed drier to remove extra water (12 kg). Further it was added and graded using vibrating screens.

Step 6: Final product was sent for QC approval.

Step 7: Upon getting approval, the material was packed in required package sizes.

Table 1: Treatment details [Ex 1]

Sr. No. Treatment compositions gram actives per hectare
T1 Compound A 30%+Compound B 7%+Compound C1 8% WG 120+28+32
T2 Compound A 30%+Compound B 7%+Compound C2 10% WG 120+28+40
T3 Compound A 24% SC + Compound B 10% EC (tank mix) 120+28
T4 Compound A 24%+Compound C1 7% WG (ready mix) 120+32
T5 Compound A 24%+Compound C2 10% WG (ready mix) 120+40
T6 Compound B 10% EC + Compound C1 20% SP (tank mix) 28+32
T7 Compound B 10% EC + Compound C2 50% WDG (tank mix) 28+40
T8 Compound A 24% SC 120
T9 Compound B 10% EC 28
T10 Compound C1 20% SP 32
T11 Compound C2 50% WDG 40
T12 Untreated Check (UTC) -
T1 and T2 are present compositions, whereas T3 to T7 are known combinations and T8 to T11-market products.

Table 2: Residual control of pod borer larval in chickpea [Ex 1]

Treatment Number Pod borer larval control (%)
at 7 days at 14 days
Control observed Control Expected Colby's ratio Synergism (Y/N) Control observed Control Expected Colby's ratio Synergism (Y/N)
T1 100.0 92.1 1.09 Y 92.6 78.4 1.18 Y
T2 100.0 92.3 1.08 Y 90.6 79.4 1.14 Y
T3 91.8 90.3 1.02 Y 73.6 77.5 0.95 N
T4 75.0 73.5 1.02 Y 46.8 52.3 0.89 N
T5 76.4 74.1 1.03 Y 50.2 54.5 0.92 N
T6 78.2 75.8 1.03 Y 48.4 56.7 0.85 N
T7 78.4 76.3 1.03 Y 52.2 58.7 0.89 N
T8 67.4 50.2
T9 70.2 54.8
T10 18.8 4.2
T11 20.4 8.6
T12 0.0 0.0

The present compositions (T1 and T2) show synergism in terms of larvae control and provide residual control of pod borer larvae infesting chickpea.

Conclusion: Among the various compositions as shown in Table 1 treatment number T1 and T2 are considered to be present inventive compositions which showed excellent synergism and effectiveness against pod borer larval control at 7 DAA and 14 DAA [days after application] for more than 90%. Particularly, at 7 DAA the pod borer larval control for T1 to T2 were 100% whereas at 14 DAA the pod borer larval control observed were (T1) 92.6% followed by (T2) 90.6% . Moreover, the colby’s ratio was found to be >1 which shows strong synergism, when compared with known combinations and market products.

Example 2: Control of Leaf eating caterpillar infesting groundnut crop
Crop : Groundnut
Location : Gondal, Gujarat
Number of Treatments: 12
Plot size : 50 sq.m. (m2)
Crop stage : 68 days after sowing.
Method of application: Foliar spray with battery operated backpacksprayer.
Water volume : 375 liter per hectare

Observation Methods
Leaf eating caterpillar (Spodoptera litura) larval control (%): Count the number of live larvae per plant. Record observations from 10 plants per plot and calculate larval control as per formula given in example 1.

Composition of Compound A 20% + Compound B 5% + Compound C4 2.5% ZC [T2 of Ex. 2]
Chemical composition Function Content (w/w)
Compound A a.i. Compound A 20.00
Compound B a.i. Compound B 5.00
Compound C4 a.i. Compound C 2.50
Mixture of heavy aromatic hydrocarbons Solvent 5.00
4,4’-diphenylmethane diisocynate Wall forming material- I 0.25
Diethylene triamine Wall forming material-II 0.15

Alkylbenzene sulfonate calcium salts Emulsifier-I 0.12
Tristyrylphenol polyethoxyester phosphate Emulsifier-II 3.50
Sodium naphthalene sulphonate formaldehyde condensate Dispersing agent-II 0.16
Acrylic graft copolymer Dispersing agent-I 2.50

Attapulgite clay Suspending agent 1.50
Polydimethylsiloxane Anti foaming agent 0.30
1,2-benzisothiazolin Preservative 0.20
Polypylene glycol Anti freezing agent 5.00
Xanthan gum thickner 0.20
Diluent water 53.62
Total 100.00
Active ingredient on 100% purity basis

Storage stability-Composition of Compound A 20% + Compound B 5% + Compound C4 2.5% ZC [T2 of Ex. 2]
Laboratory storage stability for 14 days [T2 of Ex. 2]
Parameters Specifications Initial At 54±2 0C At 0±2 0C
Compound A a.i. 19.4 to 21 20.80 20.78 20.80
Compound B a.i. 4.75 to 5.25 5.22 5.18 5.22
Compound C4 a.i. 2.375 to 2.625 2.58 2.55 2.58
Compound A suspensibility (%) 80 98.90 98.91 98.90
Compound B suspensibility (%) 80 99.00 99.10 99.00
Compound C4 suspensibility (%) 80 6.90 98.80 98.80
pH range (1% aq. Suspension) 5.5 to 8.0 98.20 6.90 6.90
Pourability(%) 95 1.03 98.20 98.20
Specific gravity 1.05-1.10 99.50 1.03 1.03
Viscocity at spindle no.62,20 rpm 350-800 cps 510 510 510
Particle size(micron) D50<3,D90<10 2.1,8.0 2.1,8.0 2.1,8.0
Persistent foam ml (after 1 minute) max. 60 nil nil nil

Room temperature storage stability up to 12 months [T2 of Ex. 2]
Parameters Specifications 1 month 6 month 12 month
Compound A a.i. 19.4 to 21 20.80 20.78 20.80
Compound B a.i. 4.75 to 5.25 5.22 5.18 5.22
Compound C4 a.i. 2.375 to 2.625 2.58 2.55 2.58
Compound A suspensibility (%) 80 98.90 98.91 98.90
Compound B suspensibility (%) 80 99.00 99.10 99.00
Compound C4 suspensibility (%) 80 6.90 98.80 98.80
pH range (1% aq. Suspension) 5.5 to 8.0 98.20 6.90 6.90
Pourability (%) 95 1.03 98.20 98.20
Specific gravity 1.05-1.10 99.50 1.03 1.03
Viscocity at spindle no.62,20 rpm 350-800 cps 510 510 510
Particle size(micron) D50<3,D90<10 2.1,8.0 2.1,8.0 2.1,8.0
Persistent foam ml (after 1 minute) max. 60 nil nil nil
The composition of Compound A 20% + Compound B 5% + Compound C4 2.5% ZC meets the all inhouse specifications for storage stability in laboratory (at 54±2 °C and At 0±2 °C for 14 days) and room temperature (for 12 months)

Manufacturing process for 100 kg batch of Compound A 20% + Compound B 5% + Compound C4 2.5% ZC [T2 of Ex. 2]
Step 1: Preparation of 2% xanthan gum solution: xantham gum (2 kg) and 1,2-benz isothiazoline-3-one (2 kg) were charged into water (96 kg) and homogenized for 12 to 18 hours prior to use.

Step 2: Preparation of CS premix: Mixture of heavy aromatic carbon (5 kg) was added into other vessel having slow stirring. Compound C4 (2.5 kg) and of alkylbenzene sulfonate calcium salts (0.12 kg), 4,4’-diphenylmethane diisocynate (0.25 kg) were also added and mixed properly for 30 to 45 minutes.

Step 3: This premix was mixed with water (20 kg) and sodium naphthalene sulphonate formaldehyde condensate (0.16 kg) under high stirring and then diethylene triamine (0.15 kg) were added and stirerd at 50°C for 3 hours and finally 2% gum solution was added (2 kg).

Step 4: DM water (23.62 kg) and 1, 2-propylene glycol (5 kg) were added into designated vessel and mixed thoroughly.

Step 5: Aluminium magnesium silicate (0.5 kg), acrylic graft copolymer (2.5 kg), tristyrylphenol polyethoxyester phosphate (3.5 kg) and polydimethylsiloxane (0.1 kg) were added into vessel having water and the contents were homogenize for 45 to 60 minutes using high shear homogenizer.
Step 6: Then compound A (20 kg) and compound B (5 kg) were added to this premix slowly and homogenized to get uniform slurry ready for grinding.

Step 7: Before grinding half the quantity of antifoam was added and then material was subjected to grinding in dyno mill till desired particle size was achieved.

Step 8: Remaining polydimethyl siloxane antifoam (0.1 kg) was added after grinding process completes and before sampling for in process analysis.

Step 9: CS premix was mixed to this milled slurry under slow stirring and homogenized for 30 to 45 minutes.

Step 10: 2% Xanthan gum solution (10 kg) was added to this formulation and send to QC for quality check.

Table 3: Treatment details [Ex 2]

Treatment Number Treatment compositions gram actives per hectare
T1 Compound A 20%+Compound B 5%+Compound C3 7.5% SE 100+25+37.5
T2 Compound A 20%+Compound B 5%+Compound C4 2.5% ZC 100+25+12.5
T3 Compound A 24% SC + Compound B 10% EC (tank mix) 100+25
T4 Compound A 24% SC + Compound C3 10% EC (tank mix) 100+37.5
T5 Compound A 24% SC + Compound C4 5% EC (tank mix) 100+12.5
T6 Compound B 5%+Compound C3 7.5% EC (ready mix) 25+37.5
T7 Compound B 10%+Compound C4 5% EC (ready mix) 25+12.5
T8 Compound A 24% SC 100
T9 Compound B 10% EC 25
T10 Compound C3 10% EC 37.5
T11 Compound C4 5% EC 12.5
T12 Untreated Check (UTC) -
T1 and T2 are present compositions, whereas T3 to T7 are known combinations and T8 to T11-market products.

Table 4: Larval control of leaf eating caterpillar in groundnut crop [Ex 2]

Treatment Number Spodoptera larval control (%)
at 5 DAA at 15 DAA
control observed control expected Colby's ratio Synergism (Y/N) control observed control expected Colby's ratio Synergism (Y/N)
T1 100.0 94.6 1.06 Y 96.8 88.7 1.09 Y
T2 99.2 93.9 1.06 Y 93.4 87.7 1.07 Y
T3 90.4 88.6 1.02 Y 78.4 80.9 0.97 N
T4 86.2 84.6 1.02 Y 68.4 75.3 0.91 N
T5 84.0 82.5 1.02 Y 65.6 73.0 0.90 N
T6 85.2 83.5 1.02 Y 67.6 72.8 0.93 N
T7 82.2 81.2 1.01 Y 66.0 70.3 0.94 N
T8 67.4 58.4
T9 65.0 54.2
T10 52.8 40.6
T11 46.4 35.2
T12 0.0 0.0
Abbreviation: DAA- days after application.
The present compositions (T1 and T2) show synergism in terms of larvae control and provide residual control of leaf eating caterpillar infesting groundnut crop.

Conclusion: Among the various compositions as shown in Table 3, T1 and T2 are the present compositions which showed excellent synergism in terms of spodoptera larveal control and provide control of leaf eating caterpillar in ground nut crop. Further, (T1) showed 100% control followed by (T2) 99.2 % control against Spodoptera larval control at 5 DAA. Moreover, (T1) showed 96.8% followed by (T2) 93.4% showed against spodoptera larval contro at 15 DAA. At last, the colby’s ratio observed was >1 which means strong synergism, when compared with known combinations and market products.

Example 3: Fruit borer larval control in okra
Crop : Okra
Location : Sonipat, Haryana
Treatments : 12
Crop age : 50 days after sowing.
Spray water volume : 400 liters per hectare.
Method of Application: Foliar spray with battery operated knapsack sprayer fitted with hollow cone nozzle.

Observation Methods:
Sucking pest complex (includes Jassid, Amrascabiguttulabiguttula; Whitefly, Bemisiatabaci; Aphid, Aphis gossypii).
Count the number of live sucking pests (jassid, whitefly and aphid) per leaf, 3 leaves per plant and 10 plants per plot on 3rd and 10thDAA. Calculate sucking pests control (%) as observed control and apply Colby’s formula to calculate synergism.

Table 5: Treatment details [Ex 3]

Treatment Number Treatment compositions gram actives per hectare
T1 Compound A 10%+Compound B 2.5%+Compound C5 30% WP 150+37.5+400
T2 Compound A 15%+Compound B 3.75%+Compound C6 30% WG 150+37.5+300
T3 Compound A 24% SC + Compound B 10% EC (tank mix) 150+37.5
T4 Compound A 24% SC + Compound C5 75% SP (tank mix) 150+400
T5 Compound A 24% SC + Compound C6 50% EC (tank mix) 150+300
T6 Compound B 10% EC + Compound C5 75% SP (tank mix) 37.5+400
T7 Compound B 3.75%+Compound C6 30% EC (ready mix) 37.5+300
T8 Compound A 24% SC 150
T9 Compound B 10% EC 37.5
T10 Compound C5 75% SP 400
T11 Compound C6 50% EC 300
T12 Untreated Check (UTC) -
T1 and T2 are present compositions, whereas T3 to T7 are known combinations and T8 to T11 are market products.

Table 6: Control of sucking pests infesting okra crop [Ex 3]

Treatment Number Sucking pest control (%)
at 3 DAA at 10 DAA
control observed control expected Colby's ratio Synergism (Y/N) control observed control expected Colby's ratio Synergism (Y/N)
T1 97.4 91.8 1.06 Y 90.2 85.4 1.06 Y
T2 98.8 92.7 1.07 Y 91.6 85.7 1.07 Y
T3 80.2 78.1 1.03 Y 65.6 67.9 0.97 N
T4 71.6 72.0 1.00 Y 57.2 61.2 0.93 N
T5 74.8 75.1 1.00 Y 57.4 61.9 0.93 N
T6 90.4 88.9 1.02 Y 78.8 82.9 0.95 N
T7 91.2 90.2 1.01 Y 80.4 83.2 0.97 N
T8 25.4 14.6
T9 70.6 62.4
T10 62.4 54.6
T11 66.6 55.4
T12 0.0 0.0

Both the present compositions (T1 to T2) show synergism in terms of sucking pests control and provide residual on 3rd and 10thday, whereas known tank mixes (T3 to T7) show synergism on 3rdday only and does not provide residual control.

Both the present compositions (T1 to T2) show strong synergism as compared to known tank mixes (T3 to T7). Higher the Colby’s ratio means stronger the synergism.

Conclusion: Among the various compositions as shown in table 5, T1 and T2 are the present compositions which show excellent results in terms of sucking pest control in okra crop. In particular, at 3 DAA (T2) showed 98.8% followed by (T1) showed 97.4% control against sucking pest control. Further at 10 DAA (T2) showed 91.6% whereas (T1) showed 90.2% control as compared to the known compositions and market products. At last, the colby’s ratio observed for the present invention was >1 which means strong synergism compared to market products.

Example 4: Control of rice leaf folder
Crop : Rice
Location : Kurud, Chhattisgarh
Treatments : 7
Spray water volume : 450 liters per hectare.
Method of Application: Foliar spray with battery operated knapsack sprayer fitted with hollow cone nozzle.

Observation Methods:
Leaf folder larval control (%): Calculate number of live larvae per hill. Record the observations from 10 hills per plot and calculate leaf folder larval control.

Table 7: Treatment details [Ex 4]

Treatment Number Treatment compositions gram actives per hectare
T1 Compound A 12%+Compound B 2.5%+Compound C7 hydrogen oxalate 30% WG 120+25+300
T2 Compound A 12%+Compound B 2.5%+Compound C8 30% WG 120+25+300
T3 Compound A 24% SC 120
T4 Compound B 10% EC 25
T5 Compound C7 hydrogen oxalate 50% SP 300
T6 Compound C8 50% SP 300
T7 Untreated Check (UTC) -
T1 and T2 are present compositions and T3 to T6 are market products.

Table 8: Control of rice leaf folder [Ex 4]

Treatment Number Leaf folder larval control (%)
at 3 DAA at 10 DAA
control observed control expected Colby's ratio Synergism (Y/N) control observed control expected Colby's ratio Synergism (Y/N)
T1 100.0 94.5 1.06 Y 98.0 89.0 1.10 Y
T2 100.0 94.3 1.06 Y 96.0 88.6 1.08 Y
T3 64.0 56.0
T4 62.0 52.0
T5 60.0 48.0
T6 58.0 46.0
T7 0.0 0.0

The present compositions (T1 and T2) show synergism in terms of rice leaf folder larval control and provide residual control.

Conclusion: Among the various compositions as shown in table 7, T1 and T2 are the present compositions which show very good results in terms of rice leaf folder larval control and provide residual control in rice crop. In particular, at 3 DAA T1 and T2 showed 100% control against rice leaf folder larval control. Further at 10 DAA (T1) showed 98% control followed by (T2) showing 96% control in rice plant as compared to the known compositions and market products. At last, the colby’s ratio observed for the present invention was >1 which means strong synergism.

Example 5: Pod borer larval control and yield in red gram.
Crop : Red gram
Location : Udalpur, Vadodara, Gujarat
Treatments : 20
Crop age : 108 days after sowing.
Spray water volume : 480 liters per hectare.
Method of Application: Foliar spray with battery operated knapsack sprayer fitted with hollow cone nozzle.

Observation Methods:
Pod borer (Helicoverpaarmigera) larval control (%): Count the number of live larvae per plant. Record observations from 10 plants per plot on 14th days after application.

Pod count: count the number of healthy and damaged (by pod borer larvae) pods of red gram per plant. Record the observations from 10 plants per plot.

Composition of Compound A 20% + Compound B 4% + Compound C11 1.2% SC [T3 of Ex. 5]
Chemical composition Function Content (w/w)
Compound A a.i. Compound A 20.00
Compound B a.i. Compound B 4.00
Compound C11 a.i. Compound C 1.20
Methylated seed oil, polyalkyleneoxide modified trisiloxane Super wetting-spreading-penetrating agent 7.50
Ethylene-propylene oxide block copolymer Dispersing agent I 5.00
Sodium naphthalene sulphonate formaldehyde condensates Dispersing agent II 1.25

Aluminum magnesium silicate Suspending agent 0.50
Polydimethylsiloxane
Anti foaming agent 0.30
Sodium benzoate Preservatives 0.20
Polypropylene glycol Anti freezing agent 5.00

Xanthan gum thickner 0.20
Diluent water 54.85
Total 100.00
Active ingredient on 100% purity basis

Storage stability-Composition of Compound A 20% + Compound B 4% + Compound C11 1.2% SC [T3 of Ex. 5]
Laboratory storage stability for 14 days [T3 of Ex. 5]
Parameters Specifications Initial At 54±2 0C At 0±2 0C
Compound A a.i. 19.4 to 21 20.80 20.76 20.8
Compound B a.i. 3.8 to 4.2 4.18 4.12 4.18
Compound C11 a.i. 1.14 to 1.26 1.25 1.23 1.25
Compound A suspensibility (%) 80 98.60 98.10 98.50
Compound B suspensibility (%) 80 98.50 98.30 98.50
Compound C11 suspensibility (%) 80 98.70 98.20 98.45
pH range (1% aq. Suspension) 5.5 to 8.0 7.05 7.15 7.05
Pourability(%) 95 98.20 98.00 98.10
Specific gravity 1.05-1.10 1.07 1.07 1.07
Viscocity at spindle no.62,20 rpm 350-800 cps 530 550 550
Particle size(micron) D50<3,D90<10 2.1,8.5 2.1,8.7 2.1,8.7
Persistent foam ml (after 1 minute) max. 60 nil nil nil

Room temperature storage stability up to 12 months [T3 of Ex. 5]
Parameters Specifications 1 month 6 month 12 month
Compound A a.i. 19.4 to 21 20.80 20.80 20.76
Compound B a.i. 3.8 to 4.2 4.18 4.18 4.17
Compound C11 a.i. 1.14 to 1.26 1.25 1.25 1.23
Compound A suspensibility (%) 80 98.50 98.50 98.40
Compound B suspensibility (%) 80 98.50 98.50 98.40
Compound C11 suspensibility (%) 80 98.70 98.60 98.60
pH range (1% aq. Suspension) 5.5 to 8.0 7.05 7.05 7.10
Pourability (%) 95 98.20 98.20 98.10
Specific gravity 1.05-1.10 1.07 1.07 1.07
Viscocity at spindle no.62,20 rpm 350-800 cps 530 530 535
Particle size(micron) D50<3,D90<10 2.1,8.5 2.1,8.5 2.1,8.6
Persistent foam ml (after 1 minute) max. 60 nil nil nil
The composition of Compound A 20% + Compound B 4% + Compound C11 1.2% SC meets the all inhouse specifications for storage stability in laboratory (at 54±2 °C and At 0±2 °C for 14 days) and room temperature (for 12 months).

Manufacturing Process for 100 kg batch of Compound A 20% + Compound B 4% + Compound C11 1.2% SC [T3 of Ex. 5]

Step 1: Preparation of 2% gum solution: Xanthan gum (2.0 kg) and sodium benzoate (2.0 kg) were charged into water (96 kg) and homogenized. It was prepared 12 to 18 hours prior to use.

Step 2: DM water (44.85 kg) and 1, 2-propylene glycol (5 kg) were charged into designated vessel and mix thoroughly.

Step 3: Sodium naphthalene sulphonate formaldehyde condensates (1.25 kg), ethylene-propylene oxide block copolymer (5.00 kg) and aluminium magnesium silicate (0.5 kg) were added into the vessel having water and the contents were homogenized for 45-60 minutes using high shear homogeniser.

Step 4: Compound A (20 kg), compound B (4 kg) and compound C11 (1.2 kg) were added to this premix slowly and homogenized to get uniform slurry ready for grinding.

Step 5: Before grinding half the quantity of polydimethylsiloxane (0.15 kg) was added and then material was subjected to grinding in dyno mill till desired particle size is achieved.

Step 6: Remaining polydimethyl siloxane (0.15 kg) antifoam was added after grinding process completes and before sampling for in process analysis.

Step 7: Finally 2% xantham gum solution (10 kg) and methylated seed oil, polyalkylenoxide modified trisiloxane (7.5 kg) were added to this formulation and homogenized for 30 minutes.

Step 8: This final formulation was sent to QC for quality check.

Composition of Compound A 16% + Compound B 3.2% + Compound C12 5% OD [T4 of Ex. 5]
Chemical composition Function Content (w/w)
Compound A a.i. Compound A 16.00
Compound B a.i. Compound B 3.20
Compound C12 a.i. Compound C 5.00
Polyoxyethylene sobitol hexaoleate Oil Emulsifier 10.00
Salts of polyolefin condensates Non-Aqueous dispersant 2.50
Ethoxylated sorbitan ester Co-Emulsifier 8.50

Bentonite clay Rheology modifier 1.50
Styrene acrylic polymer Aqueous dispersant 1.50
Methylated seed oil Oil continuous phase 51.80
Total 100.00

Active ingredient on 100% purity basis

Storage stability-Composition of Compound A 16% + Compound B 3.2% + Compound C12 5% OD [T4 of Ex. 5]
Laboratory storage stability for 14 days [T4 of Ex. 5]
Parameters Specifications Initial At 54±2 0C At 0±2 0C
Compound A a.i. 15.20 to 16.80 16.66 16.62 16.66
Compound B a.i. 3.04 to 3.52 3.48 3.44 3.48
Compound C4 a.i. 4.75 to 5.50 5.45 5.41 5.45
Compound A suspensibility (%) 80 98.90 98.10 98.80
Compound B suspensibility (%) 80 99.00 98.50 98.90
Compound C4 suspensibility (%) 80 98.90 98.10 98.80
pH range (1% aq. Suspension) 5.5 to 8.0 6.90 7.05 6.90
Pourability(%) 95 98.20 98.10 98.20
Specific gravity 1.00-1.10 1.03 1.03 1.03
Viscocity at spindle no.62,20 rpm 350-800 cps 510 520 510
Particle size(micron) D50<3,D90<10 2.1,8.0 2.1,8.2 2.1,8.1
Persistent foam ml (after 1 minute) max. 60 nil nil nil

Room temperature storage stability up to 12 months [T4 of Ex. 5]
Parameters Specifications 1 month 6 month 12 month
Compound A a.i. 15.20 to 16.80 16.66 16.66 16.62
Compound B a.i. 3.04 to 3.52 3.48 3.48 3.44
Compound C12 a.i. 4.75 to 5.50 5.45 5.45 5.41
Compound A suspensibility (%) 80 98.90 98.80 98.10
Compound B suspensibility (%) 80 98.90 98.90 98.50
Compound C4 suspensibility (%) 80 98.80 98.80 98.10
pH range (1% aq. Suspension) 5.5 to 8.0 6.90 6.90 6.90
Pourability(%) 95 98.20 98.20 98.20
Specific gravity 1.05-1.10 1.03 1.03 1.03
Viscocity at spindle no.62,20 rpm 350-800 cps 510 510 515
Particle size(micron) D50<3,D90<10 2.1,8.1 2.1,8.1 2.1,8.1
Persistent foam ml (after 1 minute) max. 60 nil nil nil
The composition of Compound A 20% + Compound B 4% + Compound C12 7.5% OD meets the all inhouse specifications for storage stability in laboratory (at 54±2 °C and At 0±2 °C for 14 days) and room temperature (for 12 months).

Manufacturing Process for 100 kg batch of Compound A 16% + Compound B 3.2% + Compound C12 5% OD [T4 of Ex. 5]

Step 1: Preparation of 15% bentonite clay solution: Bentonite clay (15 kg) was added into methylated seed oil (85 kg) and homogenized till it gets completely dissolved. It must be kept for 12 to 18 hours prior to use.

Step 2: OD Premix: Methylated seed oil (41.8 kg) was charged into a designated vessel for OD production.

Step 3: Polyoxyethylene sorbitol hexaoleate (10 kg), styrene acrylic polymer (1.5 kg), ethoxylated sorbitan ester (8.5 kg), salts of polyolefin condensates (2.5 kg) and polydimethyl siloxane (0.15 kg) were added and the contents were homogenised for 45 to 60 minutes using high shear homogenizer.

Step 4: Compound A technical (16 kg), compound B technical (3.3 kg) and compound C12 technical (5 kg) were added into this premix and homogenized for 30 to 45 minutes.

Step 5: Remaining silicon antifoam (0.15 kg) and 15% bentonite clay solution (10 kg) were added after milling to avoid foaming.

Step 6: This final formulation was sent to QC for quality check.

Table 9: Treatment details [Ex 5]

Treatment Number Treatment compositions gram actives per hectare
T1 Compound A 20%+Compound B 4%+Compound C9 6% SC 125+25+37.5
T2 Compound A 20%+Compound B 4%+Compound C10 5% SC 125+25+31.25
T3 Compound A 20%+Compound B 4%+Compound C11 1.2% SC 125+25+7.5
T4 Compound A 16%+Compound B 3.2%+Compound C12 5% OD 125+25+39
T5 Compound A 24% SC + Compound B 10% EC (tank mix) 125+25
T6 Compound A 20%+Compound C9 6% SC (ready mix) 125+37.5
T7 Compound A 20%+Compound C10 5% SC (ready mix) 125+31.25
T8 Compound A 20%+Compound C11 1.2% SC (ready mix) 125+7.5
T9 Compound A 16%+Compound C12 5% SE (ready mix) 125+39
T10 Compound B 8%+Compound C9 12% SE (ready mix) 25+37.5
T11 Compound B 8%+Compound C10 10% SC (ready mix) 25+31.25
T12 Compound B 8%+Compound C11 2.4% EC (ready mix) 25+7.5
T13 Compound B 3.2%+Compound C12 5% EC (ready mix) 25+39
T14 Compound A 24% SC 125
T15 Compound B 10% EC 25
T16 Compound C9 45% SC 37.5
T17 Compound C10 11.7% SC 31.25
T18 Compound C11 5% SG 7.5
T19 Compound C12 10% EC 39
T20 Untreated Check (UTC) -
T1 to T4 are present compositions and T5 to T13 are known tank mixes.

Table 10: Control of pod borer larvae infesting red gram [Ex 5]

Treatment Number Pod borer larval control (%)
at 5 DAA at 15 DAA
control observed control expected Colby's ratio Synergism (Y/N) control observed control expected Colby's ratio Synergism (Y/N)
T1 100.0 96.0 1.04 Y 100.0 92.2 1.08 Y
T2 100.0 96.2 1.04 Y 100.0 92.6 1.08 Y
T3 100.0 95.7 1.04 Y 100.0 91.8 1.09 Y
T4 100.0 96.0 1.04 Y 100.0 92.0 1.09 Y
T5 91.2 90.3 1.01 Y 84.6 85.2 0.99 N
T6 87.2 86.9 1.00 Y 77.8 79.7 0.98 N
T7 88.0 87.6 1.00 Y 79.2 80.8 0.98 N
T8 87.2 86.1 1.01 Y 75.0 78.4 0.96 N
T9 87.4 86.9 1.01 Y 78.0 79.0 0.99 N
T10 88.0 87.2 1.01 Y 76.6 80.0 0.96 N
T11 88.4 87.9 1.01 Y 80.0 81.1 0.99 N
T12 87.6 86.3 1.01 Y 75.2 78.8 0.95 N
T13 88.2 87.1 1.01 Y 78.4 79.4 0.99 N
T14 68.6 61.2
T15 69.2 61.8
T16 58.4 47.6
T17 60.6 50.4
T18 55.6 44.4
T19 58.2 46.0
T20 0.0 0.0

All the present compositions (T1 to T4) provide synergistic and residual control of pod borer larvae.

Table 11: Pod damage and pod count [Ex 5]

Treatment Number Pod damage (%) Number of healthy pods per plant Increase (%) in fruits over UTC

T1 0.14 215.0 133.7
T2 0.11 218.0 137.0
T3 0.15 208.0 126.1
T4 0.17 212.0 130.4
T5 2.57 187.0 103.3
T6 3.14 170.0 84.8
T7 2.86 174.0 89.1
T8 3.88 163.0 77.2
T9 3.10 167.0 81.5
T10 3.16 172.0 87.0
T11 2.83 177.0 92.4
T12 3.32 164.0 78.3
T13 2.90 165.0 79.3
T14 7.18 126.0 37.0
T15 7.12 133.0 44.6
T16 7.82 138.0 50.0
T17 7.65 134.0 45.7
T18 8.24 140.0 52.2
T19 7.95 120.0 30.4
T20 28.56 92.0 0.0

All the present compositions (T1 to T4) yielded higher number of healthy pods per plant.

Conclusion: Among the various compositions as shown in table 9, T1 to T4 are the present composition which showed excellent synergism and effectiveness against pod borer larvae control and reduced pod damage in red gram. Further, T1-T4 showed 100% control at 5 DAA and 15 DAA. At last, the Colby’s ratio observed was >1 which means strong synergism.

Furthermore, T1-T4 showed less than 0.17% of pod damage. In particular, (T2) showed 0.11%, (T1) 0.14%, (T3) 0.15% pod damage. Moreover, the numbers of healthy pods per plant for T1-T4 were more 208. In particular, (T2) showed 218 followed by (T1) 215, (T4) 212 and (T3) 208 numbers of healthy pods per plant. At last, (T2) showed 137% followed by (T1) 133.7% (T4) 130.4% and (T3) 126.1% increase in healthy fruits over UTC [untreated check] from which it can be concluded that the present composition T1-T4 showcased effectiveness and synergism in red gram crop as compared to known compositions and market products.

Example 6: Red spider mite control in brinjal crop
Crop : Brinjal
Location : Umreth, Gujarat
Number of Treatments: 16
Plot size : 50 sq.m.
Crop age : 85 days after transplanting.
Method of application : Foliar spray with battery operated backpack sprayer.
Water volume : 480 liter per hectare

Observation Methods:
Red spider mite (Tetranychusurticae): Count the number of motile stages of mite per unit area using 10X pocket microscope. Record the observations from 5 spots on randomly selected leaves (young growing leaves) per plant. Observe 10 plants per plot. Calculate mite control (%) as per formula given for thrips control.

Composition of Compound A 20% + Compound B 4% + Compound C13 1% SE [T1 of Ex. 6]
Chemical composition Function Content (w/w)
Compound A a.i. Compound A 20.00
Compound B a.i. Compound B 4.00
Compound C13 a.i. Compound C 1.00
Polyarylphenyl anionic ether sulfate, ammonium salt Emulsifier-2 3.50
Aromatic solvent C-9 Solvent 10.00
Acrylic graft copolymer Dispersing agent I 3.00

Butyl Polyalkylene Oxide blockcopolymer Dispersing agent II 4.50
Aluminium magnesium silicate Suspending agent 0.50
Polydimethylsiloxane Anti foaming agent 0.20
1,2-benzisothiazolin-3(2H)-one preservative 0.15
Citric acid Buffering agent 0.10
Polypropylene glycol Anti freezing agent 5.00
Xanthan gum thickner 0.15
Diluent water 47.90
Total 100.00
Active ingredient on 100% purity basis

Storage stability-Composition of Compound A 20% + Compound B 4% + Compound C13 1% SE [T1 of Ex. 6]
Laboratory storage stability for 14 days [T1 of Ex. 6]
Parameters Specifications Initial At 54±2 0C At 0±2 0C
Compound A a.i. 19.4 to 21 20.80 20.75 20.80
Compound B a.i. 3.8 to 4.2 4.18 4.11 4.18
Compound C4 a.i. 0.95 to 1.05 1.04 1.03 1.04
Compound A suspensibility (%) 80 98.90 97.50 98.50
Compound B suspensibility (%) 80 99.00 97.90 98.60
Compound C4 suspensibility (%) 80 98.50 97.60 98.30
pH range (1% aq. Suspension) 4.5 to 7.0 5.50 5.50 5.50
Pourability(%) 95 98.20 98.20 97.80
Specific gravity 1.05-1.10 1.07 1.07 1.07
Viscocity at spindle no.62,20 rpm 350-800 cps 550 560 560
Particle size(micron) D50<3,D90<10 2.1,8.2 2.2,8.5 2.1,8.2
Persistent foam ml (after 1 minute) max. 60 nil nil nil

Room temperature storage stability up to 12 months [T1 of Ex. 6]
Parameters Specifications 1 month 6 month 12 month
Compound A a.i. 19.4 to 21 20.80 20.80 20.75
Compound B a.i. 3.8 to 4.2 4.18 4.18 4.11
Compound C12 a.i. 0.95 to 1.05 1.04 1.04 1.03
Compound A suspensibility (%) 80 98.70 98.70 98.50
Compound B suspensibility (%) 80 98.90 98.80 98.70
Compound C4 suspensibility (%) 80 98.40 98.40 98.40
pH range (1% aq. Suspension) 4.5 to 7.0 5.50 5.50 5.50
Pourability(%) 95 98.20 98.20 98.20
Specific gravity 1.05-1.10 1.07 1.07 1.07
Viscocity at spindle no.62,20 rpm 350-800 cps 550 550 555
Particle size(micron) D50<3,D90<10 2.1,8.1 2.1,8.1 2.1,8.1
Persistent foam ml (after 1 minute) max. 60 nil nil nil
The composition of Compound A 20% + Compound B 4% + Compound C13 1 % SE meets the all inhouse specifications for storage stability in laboratory (at 54±2 °C and At 0±2 °C for 14 days) and room temperature (for 12 months).

Manufacturing Process for 100 kg batch of Compound A 20% + Compound B 4% + Compound C13 1% SE [T1 of Ex. 6]

Step 1: Preparation of 2% gum solution: Xanthan gum (2 kg) and 1,2-benzisothiazoline-3-one (2 kg) were charged into 96 kg water and homogenized and it was prepared 12-18 hour prior to use.

Step 2: EC premix- Aromatic solvent C-9 (10 kg) was added into other vessel having slow stirring. Compound B technical (4 kg) and compound C13 (1 kg) and 3.5 kg of polyarylphenyl anionic ether sulfate, ammonium salt were also added and mixed properly for 30-45 minutes.

Step 3: Charge DM water (37.9 kg), 1,2-propylene glycol (5 kg) and citric acid (0.1 kg) into designated vessel and mix thoroughly.

Step 4: Aluminum magnesium silicate (0.5 kg), acrylic graft copolymer (3 kg), butyl polyalkylene oxide block copolymer (4.5 kg) and polydimethylsiloxane (0.1 kg) were added to the vessel having water and the contents were homogenized for 45 to 60 minutes using high shear homogenizer.

Step 5: Compound A (20 kg) was added to this premix slowly and homogenized to get uniform slurry ready for grinding.

Step 6: Before grinding half the quantity of antifoam was added and then material was subjected to grinding in dyno mill till desired particle size is achieved.

Step 7: Remaining polydimethyl siloxane antifoam (0.1 kg) was added after grinding process completed and before sampling for in process anlaysis.

Step 8: EC premix was mixed to this milled slurry under slow stirring and homogenized for 30 to 45 minutes.

Step 9: Finally 7.5 kg of 2% gum solution was added to this formulation and sent to QC for quality check.

Table 12: Treatment details [Ex 6]

Treatment Number Treatment compositions gram actives per hectare
T1 Compound A 20%+Compound B 4%+Compound C13 1% SE 150+30+7.5
T2 Compound A 20%+Compound B 4%+Compound C14 3% SE 150+30+22.5
T3 Compound A 20%+Compound B 4%+Compound C15 3% SE 150+30+22.5
T4 Compound A 13.33%+Compound B 2.67%+Compound C16 20% SC 150+30+225
T5 Compound A 24% SC + Compound B 10% EC (tank mix) 125+25
T6 Compound B 4%+Compound C13 1% SE 30+7.5
T7 Compound B 4%+Compound C14 3% SE 30+22.5
T8 Compound B 4%+Compound C15 3% SE 30+22.5
T9 Compound B 2.67%+Compound C16 20% SC 30+225
T10 Compound A 24% SC 125
T11 Compound B 10% EC 25
T12 Compound C13 1.8% EC 37.5
T13 Compound C14 5% EC 31.25
T14 Compound C15 5% SC 7.5
T15 Compound C16 50% WP 39
T16 Untreated Check (UTC) -
T1 to T4 are present compositions, whereas T5 to T9 are known combinations and T10 to T15 are market products.

Table 13: Control of red spider mite infesting brinjal crop [Ex 6]

Treatment Number Red spider mite control (%)
at 7 DAA
control observed control expected Colby's ratio Synergism (Y/N)
T1 98.4 83.8 1.17 Y
T2 98.2 85.4 1.15 Y
T3 97.8 85.1 1.15 Y
T4 96.4 82.4 1.17 Y
T5 62.4 63.1 0.99 N
T6 78.6 80.2 0.98 N
T7 79.2 82.1 0.96 N
T8 78.2 81.7 0.96 N
T9 77.4 78.5 0.99 N
T10 18.4
T11 54.8
T12 56.2
T13 60.4
T14 59.6
T15 52.4
T16 0.0

All the present compositions (T1 to T4) provide synergistic control of red spider mite infesting brinjal crop.

Conclusion: Among the various compositions as shown in table 12 the present compositions T1 to T4 showcases the red spider mite control. Further, the present compositions (T1) showed 98.4% control followed by (T2) 98.2%, (T3) 97.8% and (T4) 96.4% control at 7 DAA [days after application] in brinjal crop. Moreover, the Colby’s ratio was =1 for the present compositions which shows stronger synergism as compared to the known compositions and market products.

Example 7: Whitefly control in tomato crop
Crop : Tomato
Location : Umreth, Gujarat
Number of Treatments: 10
Plot size : 50 sq.m.
Crop age : 75 days after transplanting.
Method of application : Foliar spray with battery operated backpack sprayer.
Water volume : 420 liter per hectare

Observation Methods:
Whitefly (Bemisiatabaci): Count the number of live whitefly (adult+nymphs) per trifoliate leaf, 3 leaves per plant. Calculate whitefly control (%) as observed value and apply Colby’s formula to calculate synergism.

Table 14: Treatment details [Ex 7]

Treatment Number Treatment compositions gram actives per hectare
T1 Compound A 20%+Compound B 5%+Compound C17 10% SE 125+31.3+62.5
T2 Compound A 20%+Compound B 5%+Compound C18 8% WG 125+31.3+50
T3 Compound A 24% SC + Compound B 10% EC (tank mix) 125+31.3
T4 Compound B 5%+Compound C17 10% SE (ready mix) 31.3+62.5
T5 Compound B 10%+Compound C18 16% WG 31.3+50
T6 Compound A 24% SC 125
T7 Compound B 10% EC 31.3
T8 Compound C17 10% EC 62.5
T9 Compound C18 50% WG 50
T10 Untreated Check (UTC) -
T1 and T2 are present compositions, whereas T3 to T5 are known combinations and T6 to T9 are market products.

Table 15: Whitefly control [Ex 7]

Treatment Number Whitefly control (%)
at 7 DAA
control observed control expected Colby's ratio Synergism (Y/N)
T1 97.8 90.5 1.08 Y
T2 91.4 85.2 1.07 Y
T3 66.2 65.9 1.00 Y
T4 88.6 87.4 1.01 Y
T5 81.2 80.4 1.01 Y
T6 24.6
T7 54.8
T8 72.2
T9 56.6
T10 0.0

Both the present compositions (T1 and T2) provide synergistic control of whitefly infesting tomato crop.

Conclusion: Among the various compositions as shown in table 14, T1 and T2 are present invention and it showcases the whitefly control in tomato crop. Further, the present compositions (T1) showed 97.8% control followed by (T2) 91.4% control at 7 DAA [days after application] in tomato crop. Moreover, the Colby’s ratio was =1 for the present compositions which shows stronger synergism as compared to the known compositions and market products.

The process for preparing the insecticidal composition can be modified accordingly by any person skilled in the art based on the knowledge of the manufacturing the formulation. However, all such variation and modification is still covered by the scope of present invention.
Application to the seeds is carried out before sowing, either directly on the seeds or after having pregerminated the latter. Suitable application methods include inter alia soil treatment, seed treatment, in furrow application, and foliar application. Soil treatment methods include drenching the soil, drip irrigation (drip application onto the soil), dipping roots, tubers or bulbs, or soil injection. Seed treatment techniques include seed dressing, seed coating, seed dusting, seed soaking, and seed pelleting. In furrow applications typically include the steps of making a furrow in cultivated land, seeding the furrow with seeds, applying the pesticidally active composition to the furrow, and closing the furrow. Foliar application refers to the application of the pesticidally active composition to plant foliage, e.g. through spray equipment.
The rates of application vary within wide limits and depend on the nature of the soil, the method of application, the crop plant, the pest to be controlled, the prevailing climatic conditions, and other factors governed by the method of application, the time of application and the target crop.
The present invention is suitable for use in protecting crops, plants, plant propagation materials, such as seeds, or sailor water, in which the plants are growing, from attack or infestation by animal pests. Therefore, the present invention also relates to a plant protection method, which comprises contacting crops, plants, plant propagation materials, such as seeds, or soil or water, in which the plants are growing, to be protected from attack or infestation by animal pests, with a insecticidally effective amount of the present invention.
The present invention is also suitable for use in combating or controlling animal pests. Therefore, the present invention also relates to a method of combating or controlling animal pests, which comprises contacting the animal pests, their habitat, breeding ground, or food supply, or the crops, plants, plant propagation materials, such as seeds, or soil, or the area, material or environment in which the animal pests grow, with an insecticidally effective amount of the present invention.
The lists of crops on which the insecticidal composition of the present invention is used include, but not limited to GMO (Genetically Modified Organism) and Non GMO traits, hybrids and conventional varieties of Cotton (Gossypium spp.), Paddy (Oryza sativa), Wheat (Triticum aestavum), Barley (Hordeum vulgare), Maize (Zea mays), Sorghum (Sorghum bicolor), Oat (Avena sativa), Pearl millet (Pennisetum glaucum), Sugarcane (Saccharum officinarum), Sugar beet (Beta vulgaris), Soybean (Glycin max), Groundnut/Peanut (Arachis hypogaea), Sunflower (Helianthus annuus), Mustard (Brassica juncea), Rape seed (Brassica napus), Sesame (Sesamum indicum), Green gram (Vigna radiata), Black gram (Vigna mungo), Chickpea (Cicer aritinum), Cowpea (Vigna unguiculata), Red gram (Cajanus cajan), French bean (Phaseolus vulgaris), Indian bean (Lablab purpureus), Horse gram (Macrotyloma uniflorum), Field pea (Pisum sativum), Cluster bean (Cyamopsis tetragonoloba), Lentils (Lens culinaris), Brinjal (Solanum melongena), Cabbage (Brassica oleracea var. capitata), Cauliflower (Brassica oleracea var. botrytis), Okra (Abelmoschus esculentus), Onion (Allium cepa L.), Tomato (Solanum lycopersicun), Potato (Solanum tuberosum), Sweet potato (Ipomoea batatas), Chilly (Capsicum annum), Bell pepper (Capsicum annum), Garlic (Allium sativum), Cucumber (Cucumis sativus), Muskmelons (Cucumis melo), Watermelon (Citrullus lanatus), Bottle gourd (Lagenaria siceraria), Bitter gourd (Momordica charantia), Radish (Raphanus sativus), Carrot (Dacus carota subsp. sativus), Turnip (Brassica rapa rapa), Apple (Melus domestica), Banana (Musa spp.), Citrus groups (Citrus spp.), Grape (Vitis vinifera), Guava (Psidium guajava), Mango (Mangifera indica), Papaya (Carica papaya), Pineapple (Ananas comosus), Pomegranate (Punica granatum), Sapota (Manilkara zapota), Tea (Camellia sinensis), Coffea (Coffea Arabica), Turmeric (Curcuma longa), Ginger (Zingiber officinale), Cumin (Cuminum cyminum), Black Pepper (Piper nigrum), Mentha ( Mentha spp.), Rose (Rosa spp.), Jasmine (Jasminum spp.), Marigold ( Tagetes spp.), Common daisy (Bellis perennis), Dahlia (Dahlia hortnesis), Gerbera (Gerbera jamesonii), Carnation (Dianthus caryophyllus).
Crops are to be understood as also including those crops which have been rendered tolerant to herbicides or classes of herbicides (e.g. ALS-, GS-, EPSPS-, PPO-, ACCase- and HPPD-inhibitors) by conventional methods of breeding or by genetic engineering. An example of a crop that has been rendered tolerant to imidazolinones, e.g. imazamox, by conventional methods of breeding is Clearfield® summer rape (canola). Examples of crops that have been rendered tolerant to herbicides by genetic engineering methods include e.g. glyphosate- and glufosinate-resistant maize varieties commercially available under the trade names RoundupReady® and LibertyLink®.
Crops are also to be understood as being those which have been rendered resistant to harmful insects by genetic engineering methods, for example Bt maize (resistant to European corn borer), Bt cotton (resistant to cotton boll weevil) and also Bt potatoes (resistant to Colorado beetle). Examples of Bt maize are the Bt 176 maize hybrids of NK® (Syngenta Seeds). The Bt toxin is a protein that is formed naturally by Bacillus thuringiensis soil bacteria. Examples of toxins, or transgenic plants able to synthesise such toxins, are described in EP-A-451 878, EP-A-374 753, WO 93/07278, WO 95/34656, WO 03/052073 and EP-A-427 529. Examples of transgenic plants comprising one or more genes that code for an insecticidal resistance and express one or more toxins are KnockOut® (maize), Yield Gard® (maize), NuCOTIN33B® (cotton), Bollgard® (cotton), NewLeaf® (potatoes), NatureGard® and Protexcta®. Plant crops or seed material thereof can be both resistant to herbicides and, at the same time, resistant to insect feeding (“stacked” transgenic events). For example, seed can have the ability to express an insecticidal Cry3 protein while at the same time being tolerant to glyphosate.
Crops are also to be understood to include those which are obtained by conventional methods of breeding or genetic engineering and contain so-called output traits (e.g. improved storage stability, higher nutritional value and improved flavour).
Other useful plants include turf grass for example in golf-courses, lawns, parks and roadsides, or grown commercially for sod, and ornamental plants such as flowers or bushes.
The insecticidal composition of the present invention is used to control insects-pests and plant parasitic mites. The major insects pests are belongs to the order Hemiptera, for example, rice leafhopper/green leaf hopper (GLH) Nephotettix nigropictus, rice brown plant hopper (BPH) Nilaparvata lugen, rice backed plant hopper (WBPH) Sogatella furcifera , Apple Mealy bug Phenococcus aceris, bean aphid Aphis fabae, black citrus aphid Toxoptera aurantii, citrus black scale Saissetia oleae, cabbage aphid Brevicoryne brassicae, Lipaphis erysimi, citrus red scale Aonidiella aurantii, yellow scale Aonidiella citrine, citrus mealybug Planococcus citri, corn leaf aphid Rhopalosiphum maidis, aphid Aphis gossypii, jassid Amrasca biguttula biguttla, mealy bug Planococcus spp. And Pseudococcus spp., cotton stainer Dysdercus suturellus, whitefly Bemisia tabaci, cowpea aphid Aphis crassivora, grain aphid Sitobion avenae, golden glow aphid Uroleucon spp., grape mealybug Pseudococcus maritimus, green peach aphid Myzus persicae, greenhouse whitefly Trialeurodes vaporariorum, papaya mealy bug Pracoccus marginatus, pea aphid Acyrthosiphon pisum, sugarcane mealybug Saccharicoccus sacchari, potato aphid Myzus persicae, potato leaf hopper Empoasca fabae, cotton whitefly Bemisia tabaci, tarnished plant bug Lygus lineolaris, wooly apple aphid Eriosoma lanigerum, mango hopper Amritodus atkinsoni, Idioscopus spp.; order Lepidoptera, army worm Mythimna unipuncta, asiatic rice borer Chilo suppressalis, bean pod borer Maruca vitrata, beet armyworm Spodoptera exigua, black cutworm Agrotis ipsilon, bollworm Helicoverpa armigera , cabbage looper Trichoplusia ni, codling moth Cydia pomonella, croton caterpillar Achea janata, diamond backmoth Plutella xylostella, cabbage worm Pieris rapae, pink bollworm Pectinophora gossypiella, sugarcane borer Diatraea saccharalis, sugarcane early shoot borer Chilo infuscatellus tobacco budworm Heliothis virescens, tomato fruitworm Helicoverpa zea, velvet bean caterpillar Anticarsia gemmatalis, yellow stem borer Scirpophaga incertulas, spotted bollworm Earias vittella, rice leaffolder Cnaphalocrocis medinalis, pink stem borer Sesamia spp., tobacco leafeating caterpillar Spodoptera litura; brinjal fruit and shoot borer Leucinodes orbonalis, bean pod borer Maruca vitrata, Maruca testulalis, armyworm Mythimna separata, cotton pinkbollworm Pectinophora gossypiella, citrus leafminer Phyllocnistis citrella, cabbage butterfly Pieris bras-sicae, diamond backmoth Plutella xylostella, paddy stem borer Scirpophaga excerptallis, Scirpophaga incertulas, Scirpophaga innotata, wheat stem borer Sesamia inferens, Sitotroga cerealella, Spilosoma obliqua, fall armyworm Spodoptera frugiperda, Spodoptera littoralis, Spodoptera litura, Trichoplusia ni, Tryporyza nivella, Tryporyza incertulas, Tuta absoluta; from the order Coleoptera, for example, apple twig borer Amphicerus spp., corn root worm Diabrotica virgifera, cucumber beetle diabrotica balteata, boll weevil Anthonomus grandis, grape flea beetle Altica chalybea, grape root worm Fidia viticola, grape trunk borer Clytoleptus albofasciatus, radish flea beetle Phyllotreta armoraciae, maize weevil Sitophilus zeamais, northern corn rootworm Diabrotica barberi, rice water weevil Lissorhoptrus oryzophilus, Anthonomus grandis, Bruchus lentis, Diabrotica semipunctata, Diabrotica virgifera, Dicladispa armigera, Epila-chna varivestis, various species of white grubs are Holotrichia bicolor, Holotrichia consanguinea, Holotrichia serrata, Leptinotarsa decemlineata, Phyllotreta chrysocephala, Popillia japonica etc; from the order Orthoptera, for example, Gryllotalpa spp., Locusta spp., and Schistocerca is spp.; from the order Thysanoptera, for example, Frankliniella spp., Thrips palmi, Thrips tabaci and Scirtothrips dorsalis; termites (Isoptera), e.g. Calotermes flavicollis, Coptotermes formosanus, Heterotermes aureus, Leucotermes flavipes, Microtermes obesi, Odontotermes obesus, Reticulitermes flavipes, Termes natalensis; from the order Heteroptera, for example, Dysdercus spp., Leptocorisa spp., from the order Hymenoptera, for example, Solenopsis spp. ; from the order Diptera, for example, Antherigona soccata, Dacus spp., Liriomyza spp., Melanagromyza spp.
The plant parasitic mites from the order Acarina, for example, Aceria mangiferae, Brevipalpus spp., Eriophyes spp., Oligonychus mangiferus, Oligonychus punicae, Panonychus citri, Panonychus ulmi, Polyphagotarsonemus latus, Tarsonemus spp., Tetranychus urticae, Tetranychus cinnabarinus.
The present invention has been described with reference to specific embodiment which is merely illustrative and not intended to limit the scope of the invention as defined in the present complete specification.

We Claim:

1. A synergistic ternary insecticidal composition comprising:

A) Compound A: 10 to 50 w/w% of N’-tert-butyl-N’-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide;
B) Compound B: 1 to 20 w/w% of 44-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-N-[(Z)-methoxyiminomethyl]-2-methylbenzamide;
C) Compound C: 1 to 30 w/w% of at least one compound selected from group of insecticides and agrochemically acceptable excipients.

2. A synergistic ternary insecticidal composition as claimed in claim 1, wherein insecticides for Compound C is selected from the group consisting of

C1, N-[(6-chloropyridin-3-ylmethyl-N’-cyano-N-methylemethanimidamide,

C2, 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3-methyl-2-nitroguanidine,

C3, (2-methyl-3-phenylphenyl)methyl (1R,3R)-3-[(Z)-2-chloro-3,3,3- trifluoroprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate,

C4, [(R)-cyano-(3-phenoxyphenyl)methyl] (1S,3S)-3-[(Z)-2-chloro-3,3,3-trifluoroprop-1-enyl]-2,2-dimethylcyclopropane-1 -carboxylate,

C5, N-[methoxy (methylsulfanyl)phosphoryl]acetamide,

C6, 4-bromo-2-chloro-1-[ethoxy(propylsulfanyl)phosphoryl]oxybenzene,

C7, N,N-dimethyltrithian-5-amine;oxalic acid,

C8, S-[3-carbamoylsulfanyl-2-(dimethylamino)propyl] carbamothioate,

C9, mixture of 50–95% (2R,3aS,5aR,5bS,9S,13S,14R,16aS,16bR)-2-[(6-deoxy-2,3,4-tri-O-methyl-a-L -mannopyranosyl)oxy]-13-{[4-(dimethylamino)-2,3,4,6-tetradeoxy-ß- D erythropyranosyl]oxy}-9- ethyl-2,3,3a,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b hexadecahydro-14-methyl-1H-as-indaceno[3,2-d]oxacyclododecine-7,15 dione and 50–5% (2S,3aR,5aS,5bS,9S,13S,14R,16aS,16bS)-2-[(6-deoxy-2,3,4-tri-O-methyl-a-L-mannopyranosyl)oxy]-13-{[4-(dimethylamino)-2,3,4,6 tetradeoxy-ß-D-erythropyranosyl]oxy}-9-ethyl 2,3,3a,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-hexadecahydro-4,14-dimethyl-1H-as-indaceno[3,2-d]oxacyclododecine-7,15 –dione,

C10, (2R,5R,9R,10S,14R,15S,19S)-15-[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy-7-[(2R,3R,4R,5S,6S)-4-ethoxy-3,5 -dimethoxy-6-methyloxan-2-yl]oxy-19-ethyl-14-methyl-20 oxatetracyclo [10.10.0.0.0]docos-11-ene-13,21-dione,

C11, (1'R,2R,3S,4'S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-2-[(2S)-butan-2 -yl]-21',24'-dihydroxy-12'-[(2R,4S,5S,6S)-4-methoxy-5-[(2S,4S,5S,6S)-4 -methoxy-6-methyl-5-(methylamino)oxan-2-yl]oxy-6-methyloxan-2-yl]oxy -3,11',13',22'-tetramethylspiro[2,3-dihydropyran-6,6'-3,7,19 -trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2'-one,

C12, N-[[3-chloro-4-[1,1,2-trifluoro-2-(trifluoromethoxy)ethoxy]phenyl]carbamoyl]-2,6-difluorobenzamide,

C13, 1'R,2R,3S,4'S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-2-butan-2-yl-21',24'-dihydroxy-12'-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-3,11',13',22' -tetramethylspiro[2,3-dihydropyran- 6,6'-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2' -one;(1'R,2R,3S,4'S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-21',24' -dihydroxy-12'-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6 -methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-3,11',13',22' -tetramethyl-2-propan-2-ylspiro[2,3-dihydropyran-6,6'-3,7,19 -trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2'-one,

C14, (4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide,

C15, tert-butyl 4-[[(E)-(1,3-dimethyl-5 phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate,

C16, 1-tert-butyl-3-[4-phenoxy-2,6-di(propan-2-yl)phenyl]thiourea,

C17, 2-[1-(4-phenoxyphenoxy)propan-2-yloxy]pyridine and

C18, N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide.

3. A synergistic ternary insecticidal composition as claimed in claim 1, wherein the agrochemically acceptable excipients are selected from the group consisting of wetting-spreading-penetrating agent(s), dispersing agent(s), suspending agent(s), anti freezing agent(s), thickener(s), preservative(s), emulsifier(s), anti foaming agent(s), buffering agent(s), rheology modifier(s), wetting agent(s), carrier(s) and solvent(s).

4. A synergistic ternary insecticidal composition as claimed in claim 1, wherein the composition is in the form of wettable granule/ water dispersible granule (WG/WDG), mixed formulation (ZC), suspension concentrate (SC), oil dispersion (OD) and suspo emulsion (SE).

5. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the dispersing agent for wettable granule (WG) is selected from alkylnaphthalene sulfonate sodium salt, alkylnaphthalene sulfonate, modified polyacrylate copolymer, sodium polycarboxylate, naphthalenesulfonic acid, sodium salt condensates with formaldehyde, polyalcoxylated alkylphenol, naphthalenesulfonic acid formaldehyde condensate, methylnaphthalene-formaldehyde-condensate sodium salt, naphthalene condensates, lignosulfonates, polyacrylates, phosphate esters, calcium lignosulfonate, lignin sulfonate sodium salt and mixture thereof.

6. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the carrier for wettable granule (WG) is selected from china clay, silica, lactose anhydrous, ammonium sulfate, sodium sulfate anhydrous, corn starch, urea, EDTA, urea formaldehyde resin, diatomaceous earth, kaolin, bentonite, kieselguhr, fuller's earth, attapulgite clay, bole, loess, talc, chalk, dolomite, limestone, lime, calcium carbonate, powdered magnesia, magnesium oxide, magnesium sulphate, sodium chloride, gypsum, calcium sulphate, pyrophyllite, silicates, silica gels, fertilizers, ammonium sulphate, ammonium phosphate, ammonium nitrate and urea, natural products of vegetable, grain meals, flours, bark meals, wood meals, nutshell meals, cellulosic powders, synthetic polymeric materials, ground-powdered plastics, resins, bentonites, zeolites, titanium dioxide, iron oxides, hydroxides, aluminium oxides, hydroxides, organic materials such as bagasse, charcoal, synthetic organic polymers or mixture thereof.

7. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the wetting agent for wettable granule (WG) is selected from sodium N-methyl-N-oleoyl taurate, alkylated naphthalene sulfonate, sodium salt, mixture of isomers of dibutylnaphthalene sulphonic acid sodium salt, sodium di-isopropylnaphthalenesulphonate, sodium isopropyl naphthalene sulphonate, sodium lauryl sulfate, dioctyl sulfate, alkyl naphthalene sulfonates, phosphate esters, sulphosuccinates, non-ionic, tridecyl alcohol ethoxylate, alkyl-alkaryl sulfonates, alkylbenzene sulfonates, alpha olefin sulfonate, alkyl naphthalene sulfonates, ethoxylated, non-ethoxylated alkyl, alkaryl carboxylates, alkyl, alkaryl phosphate esters, alkyl polysaccharide, di, mono alkyl sulfosuccinate derivatives, alpha olefin sulfonates, alkyl naphthalene sulfonates, dialkyl sulphosuccinates, butyl, dibutyl, isopropyl, di-isopropyl naphthalene sulfonate salts, C12 alkyl benzene sulfonate, C10-C16 alkyl benzene sulfonate, organosilicons surfactants, trisiloxane ethoxylate, polydimethylsiloxane, polyoxyethylene methyl polysiloxane, polyoxyalkylene methyl polysiloxane, polyether polymethyl siloxane copolymer, trisiloxaneheptamethyl, polyalkyleneoxide modified heptamethyl trisiloxane, polyether modified polysiloxane and mixture thereof.

8. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the antifoaming agent for wettable granule (WG) is selected from polydimethylsiloxane.

9. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the emulsifier for mixed formulation (ZC) is selected from alkylbenzene sulfonate calcium salts, tristyrlphenol polyethoxyester phosphate and mixture thereof.

10. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the wall forming material for mixed formulation (ZC) is selected from tetramethylene diisocyanate, pentamethylene diisocyanate, hexamethylene diisocyanate, toluene diisocyanate, 4,4-diphenylmethenediisocyanate (MDI), polymethylene polyphenylene isocyanate, 2,4,4’-diphenyl ether tri-isocyanate, 3,3’-dimethyl-4,4’-diphenyl diisocyanate, 3,3’-dimethoxy-4,4’-diphenyl diisocyanate, 1,5-naphthylene diisocyanate, 4,4’4"-triphenylmethane tri-isocyanate, toluene diisocyanate, polymethylene polyphenylisocyanate, polyurethane comprising of polyfunctional isocyanate, a polyamine in polarized form, diethylene triamine, Ammonia, hexamine, ethylenediamine, propylene-1,3-diamine, tetramethylenediamine, pentamethylenediamine, 1,6-hexamethylenediamine, diethylenetriamine, triethylenetetramine, tetraethylenepentamine, pentaethylenehexamine, 4,9-dioxadodecane-1, 12-diamine, 1,3-phenylenediamine, 2,4-toluenediamine, 2,6-toluenediamine, 4,4’-diaminodiphenylmethane, 1,3-phenylenediamine, 1,5-diaminonaphthalene, 1,3,5-triaminobenzene, 2,4,6-triaminotoluene, 1,3,6-triaminonaphthalene, 2,4,4'-triaminodiphenyl ether, 3,4,5-triamino-1,2,4-triazole, 1,4,5,8-tetraminoanthraquinone or mixture thereof.

11. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the dispersing agent for mixed formulation (ZC) is selected from ethoxylated lignosulfonic acid salts, lignosulfonic acid salts, oxidized lignins, lignin salts, salts of styrenemaleic anhydride copolymers, polyvinyl alcohol, salts of partial esters of styrene-maleic anhydride copolymers, partial salts of polyacrylic acid, partial salts of polyacrylic acid terpolymers, lignosulfonate of calcium, sodium, a modified kraft lignin with a high sulfonic acid group , dibutylnaphthalenesulfonic acid, fatty acids, alkyl-alkylarylsulfonates, alkyl sulfates, lauryl ether sulfates, fatty alcohol sulfates, salts of sulfated hexa, heptadecanols, octadecanols, fatty alcohol glycol ethers, condensates of sulfonated naphthalene-its derivatives with formaldehyde, condensates of naphthalene, naphthalenesulfonic acids with phenol, naphthalenesulfonic acids with formaldehyde, polyoxyethylene octylphenol ether, ethoxylated isooctyl, octyl- nonylphenol, alkyl phenyl polyglycol ethers, tributyl phenyl polyglycol ethers, alkyl aryl polyether alcohols, tridecyl alcohol, fatty alcohol/ethylene oxide condensates, ethoxylated castor oil, polyoxyethylene alkyl ethers, polyoxypropylene alkyl ethers, lauryl alcohol polyglycol ether acetate, sorbitol esters, lignin-sulphite waste liquors, proteins, denatured proteins, polysaccharides, ammonium salts of sulfonates, sulfates, phosphates, carboxylates, alkylarylsulfonates, diphenyl sulfonates, alpha-olefin sulfonates, sulfonates of fatty acids, oils, sulfonates of ethoxylated alkylphenols, sulfonates of condensed naphthalene, sulfonates of dodecyl-tridecyl benzenes, sulfonates of naphthalene, alkylnaphthalenes, sulfosuccinates, alkoxylates, N-alkylated fatty acid amides, amine oxides, esters, sugar-based surfactants, alkylphenols, amines, tallow amine, amides, aryl phenols, fatty acids, fatty acid esters, alkoxylated ethylene oxide, propylene oxide, ethylene oxide, polyethylene oxide, polypropylene oxide, polyacids, polybases, sodium naphthalene sulphonate formaldehyde condensates, acrylic graft copolymer and mixture thereof.

12. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the solvent for mixed formulation (ZC) is selected from hydrocarbon solvent such as an aliphatic, cyclic, aromatic hydrocarbons, toluene, xylene, paraffin, tetrahydronaphthalene, alkylated naphthalene, their derivatives, mineral oil fractions of medium to high boiling point such as kerosene, diesel oil, coal tar oils, a vegetable oil such as corn oil, rapeseed oil, a fatty acid ester such as C1-C10-alkylester of a C10-C22-fatty acid, methyl-ethyl esters of vegetable oils such as rapeseed oil methyl ester, corn oil methyl ester, acetophenone, 2-heptanon, 3-heptanone, 2-hexanone, 5-methyl-2-hexanone , 5-methyl-3-heptanone, 3-methyl-2-hexanone, 4-methyl-2-hexanone, 2-methyl-3-hexanone, 4-methyl-3-hexanone, 5-methyl-3-hexanone, 3-ethyl-2-pentanone, 3,3-dimethyl-2-pentanone, 3,4-dimethyl-2-pentanone, 4,4-dimethyl-2-pentanone, 2,2-dimethyl-3-pentanone , 2,4-dimethyl-3-pentanone, 2-octanone, 2,5-dimethyl-3-hexanone, 2,2-dimethyl-3-hexanone, 3,3-dimethyl-2-hexanone, 3,4-dimethyl-2-hexanone, 4,4-dimethyl-3-hexanone, 3-ethyl-4-methyl-2-pentanone, 2-methyl-3-heptanone, 2-methyl-4-heptanone, 3-methyl-2-heptanone, 3-methyl-4-heptanone, 5-methyl-3-heptanone, 6-methyl-2-heptanone, 6-methyl-3-heptanone, 3-octanone, 4-octanone, 2,2,4-trimethyl-3-pentanone, 3-ethyl-3-methyl-2-pentanone, 5-methyl-2-heptanone, isoprene or mixture thereof.

13. A synergistic ternary insecticidal composition claimed in claim 3, wherein the thickner for mixed formulation (ZC) is selected from xanthan gum, carboxy methyl cellulose, attapulgite clay, bentonite clay and mixture thereof.

14. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the suspending agent for mixed formulation (ZC) is selected from bentonite clay, aluminium magnesium silicate, silica, attapulgite clay and mixture thereof.

15. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the antifoaming agent for mixed formulation (ZC) is selected from silicone oil, silicone compound, C10~C20 saturated fat acid compounds, C8~C10 aliphatic alcohols compound, silicone antifoam emulsion, Dimethyl siloxane, polydimethyl siloxane, vegetable oil based antifoam, tallow based fatty acids, polyalkyleneoxide modified polydimethylsiloxane and mixture thereof.

16. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the antifreezing agent for mixed formulation (ZC) is selected from ethylene glycol, propane diols, glycerine, urea, glycol, monoethylene glycol, diethylene glycol, polypropylene glycol, polyethylene glycol, magnesium sulphateheptahydrate, sodium chloride and mixture thereof.

17. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the preservatives for mixed formulation (ZC) is selected from 1,2-benzisothiazolin-3(2H)-one, 1,2-benzisothiazolin, sodium salt, sodium benzoate, 2-bromo-2-nitropropane-1,3-diol, formaldehyde, sodium o-phenyl phenate, 5-chloro-2-methyl-4-isothiazolin-3-one, 2-methyl-4-isothiazolin-3-one and mixture thereof.

18. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the wetting spreading-penetrating agent(s) for suspension concentrate (SC) is selected from methylated seed oil, polyakyleneoxide modified trisiloxane, trisiloxane ethoxylate, heptamethyl trisiloxane, modified polyalkyleneoxide, modified heptamethyl trisiloxane, polyether modified polysiloxane, polyalkyleneoxide modified trisiloxane, polyalkyleneoxide modified polydimethylsiloxane, liquid or powder form and mixture thereof.

19. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the dispersing agent(s) for suspension concentrate (SC) is selected from ethylene-propylene oxide block coplolymer, naphthalenesulfonic acid, sodium salt condensate with formaldehyde, alkylated naphthalene sulfonate, sodium salt, sodium salt of naphthalene sulfonate condensate, sodium ligno sulfonate, sodium polycarboxylate, EO/PO based copolymer, phenol sulfonate, sodium methyl oleoyl taurate, styrene acrylic acid copolymer, propylene oxide-ethylene oxide-copolymer, polyethylene glycol 2,4,6-tristyrylphenyl ether, tristyrylphenol-polyglycol ether-phosphate, tristyrylphenole with 16 moles EO, tristyrylphenol-polyglycol ether-phosphate, oleyl-polyglycol ether with ethylene oxide, tallow fatty amine polyethylene oxide, nonylphenol polyglycol ether with 9-10 moles ethylene oxide, sodium naphthalene sulphonate formaldehyde condensates and mixture thereof.

20. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the suspending agent SC for suspension concentrate (SC) is selected from aluminum magnesium silicate, bentonite clay, silica, attapulgite clay and mixture thereof.

21. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the antifoaming agent for suspension concentrate (SC) is selected from silicone antifoam emulsion, dimethyl siloxane, polydimethylsiloxane, vegetable oil based antifoam, tallow based fatty acids and mixture thereof.

22. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the antifreezing agent for suspension concentrate (SC) is selected from ethylene glycol, propane diols, glycol, monoethylene glycol, diethylene glycol, polypropylene glycol, polyethylene glycol, glycerin, urea, magnesium sulfate heptahydrate, sodium chloride and mixture thereof.

23. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the preservatives for suspension concentrate (SC) is selected from is 1,2-benzisothiazolin-3(2H)-one, sodium salt, sodium benzoate, 2-bromo-2-nitropropane-1,3-diol, formaldehyde, sodium o-phenyl phenate, 5-chloro-2-methyl-4-isothiazolin-3-one, 2-methyl-4-isothiazolin-3-one and mixture thereof.

24. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the thickner for suspension concentrate (SC) is selected from xanthan gum, PVK, carboxymethyl celluloses, polyvinyl alcohols, gelatin, sodium carboxymethylcellulose, hydroxyethyl cellulose, sodium polyacrylate, modified starch, acacia gum and mixture thereof.

25. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the emulsifying agent for oil dispersion (OD) is selected from castor oil ethoxylates, alcohol ethoxylates, fatty acid ethoxylates, sorbitan ester ethoxylates, sulphosuccinate, calcium salts of dodecylbenzene sulphonate, alkylammonium salts of alkylbenzene sulphonate, alkylsulphosuccinate salts, ethylene oxide-propylene oxide block copolymers, ethoxylated alkylamines, ethoxylated alkyl phenols, polyoxyethylene sorbitan monolaurate, polyxyethylene sobitol hexaoleate, ethoxylated sorbiton ester and mixture thereof.

26. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the dispersing agent for oil dispersion (OD) is selected from alkyl sulfonates, alkyl benzene sulfonates, alkyl aryl sulfonates, alkylphenolalkoxylates, tristyrylphenol ethoxylates, natural fatty ethoxylate alcohols, synthetic fatty ethoxylate alcohols, natural fatty acid alkoxylates, synthetic fatty acid alkoxylates, natural fatty alcohols alkoxylates, synthetic fatty alcohols alkoxylates, alkoxylated alcohols, n-butyl alcohol poly glycol ether, block copolymers, ethylene oxide-propylene oxide block copolymers, ethylene oxide-butylene oxide block copolymers, fatty acid-polyalkylene glycol condensates, polyamine-fatty acid condensates, polyester condensates, salts of polyolefin condensates, sodium ligno sulfonate, sodium ploycarboxylate, EO/PO based copolymer, phenol sulfonate, sodium methyl oleoyl taurate, styrene acrylic acid copolymer, propyleneoxide-ethyleneoxide-copolymer, polyethylene glycol 2,4,6-tristyrylphenyl ether, tristyrylphenol-polyglycolether-phosphate, tristyrylphenole with 16 moles EO, tristyrylphenol-polyglycolether-phosphate, oleyl-polyglycolether with ethylene oxide, tallow fattyamine polyethylene oxide, nonylphenol polyglycolether with 9-10 moles ethylene oxide, salts of polyolefin condensates, styrene acrylic polymer and mixture thereof.

27. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the rheology modifier for oil dispersion (OD) is selected from bentonite clay.

28. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the solvent for oil dispersion (OD) is selected from vegetable oil its alkylated or ethoxylated or esterified form, the alkylated vegetable oil, methylated vegetable oil, ethylated vegetable oil, the vegetable oils, olive oil, kapok oil, castor oil, papaya oil, camellia oil, sesame oil, corn oil, rice bran oil, cotton seed oil, soybean oil, groundnut oil, rapeseed-mustard oil, linseed oil, tung oil, sunflower oil, safflower oil, coconut oil, the alkyl ester of vegetable oils, methyl ester, ethyl ester, propyl ester, butyl ester of vegetable oils, methylated seed oil, polyalkyleneoxide modified polydimethylsiloxane alkylphenol ethoxylate, rapeseed oil methyl ester, rapeseed oil ethyl ester, rapeseed oil propyl esters, rapeseed oil butyl esters, soybean oil methyl ester, soybean oil ethyl ester, soybean oil propyl ester, soybean oil butyl ester, castor oil methyl ester, castor oil ethyl ester, castor oil propyl ester, castor oil butyl ester, cotton seed oil methyl ester, cotton seed oil ethyl ester, cotton seed oil butyl ester, cotton seed oil propyl ester, tall oil fatty acids esters-tallow methyl ester, tallow ethyl ester, tallow propyl ester, bio-diesel, mineral oil, aromatic solvents, isoparaffin, base solvent, fatty acid amides, C1-C3 amines, alkylamines, alkanolamines with C6-C18 carboxylic acids, fatty acids, alkyl esters of fatty acids, methyl oleate, ethyl oleate, methyl soyate, ethyl soyate, alkyl benzenes, alkylnaphthalenes, polyalkylene glycol ethers, fatty acid diesters, fatty alkylamides, diamides, dialkylene carbonates, ketones, alcohols, cyclohexanone, acetophenone, NMP, dimethyl sulfoxide, benzyl alcohol, butanol, N-octanol, N-propanol, 2-ethyl hexanol, tetrahydro furfuryl alcohol, isophorone, fatty acid dimethyl amide, 2-hexylethyl lactate, propylene carbonate, methylated seed oil and mixtures thereof.

29. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the emulsifier(s) for suspo emulsion (SE) is selected from salts of dodecylbenzene sulphonate, Ca-salts, amine salts, sulphonates of other C11-C16 alkylbenzenes, alkylether sulphates, alkylphenoletherphosphates, ester phosphates, non-ionic surfactants, alkoxylated alcohols, alkylphenols, ethoxylated fatty acids, ethoxylated vegetable oils, ethoxylated castor oil, fatty acid esters, sorbitol, their ethoxylated derivatives, ethoxylated amines, condensates of glycerol, catanionic emulsifiers, cationic amine, alkylsulphonate, ether sulphonate, ether phosphate, alkoxylated alcohols, alkoxylated alkylphenols, ethoxylated fatty acids, ethoxylated vegetable oils, ethoxylated tristyrylphenol-tristyrlphenol with 16 moles EO, tristyrylphenol-polyglycolether-phosphate, fatty acid esters of sorbitol, ethoxylated derivatives thereof, ethoxylated amines, condensates of glycerol, sulfonated alkylbenzenes in the range C11-C16, salts thereof, alkylether sulphates, alkyletherphosphates, alkylphenoletherphosphates, salts of phosphate esters of ethoxylated tristyrylphenol, salts of sulphated ethers of ethoxylated tristyrylphenol, catanionic system, alkylsulphonate, alkylethersulphonate, ether sulphate, ether phosphate, alkyletherphosphate, nonylphenol polyethoxyethanols, castor oil polyglycol ethers, poly adducts of ethylene oxide, poly adducts of polypropylene, tributyl phenoxy polyethoxy ethanol, octyl phenoxy polyethoxy ethano, polyarylphenyl anionic ether sulphate, ammonium salts and mixture thereof.

30. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the dispersing agent(s) for suspo emulsion (SE) is selected from butyl polyalkylene oxide block copolymer, polyesters, polyamides, polycarbonates, polyurea, polyurethanes, acrylic polymers, acrylic graft copolymer, styrene copolymers, butadiene copolymers, polysaccharides, starch, cellulose derivatives, vinylalcohol, vinylacetate, vinylpyrrolidone polymers, copolymers, polyethers, epoxy, phenolic, melamine resins, polyolefins, define copolymers, acrylate polymers, polymethacrylate, polyethyl methacrylate, polymethylmethacrylate, acrylate copoylmers, styrene-acrylic copolymers, polystyrene-co maleic anhydride, cellulosic polymers, ethyl cellulose, cellulose acetate, cellulose acetate butyrate, acetylated mono, di, triglycerides, polyvinylpyrrolidone, vinyl acetate polymer, vinyl acetate copolymers, polyalkylene glycol, styrene butadiene copolymers, polyorthoesters, alkyd resins, mixtures of two or more of these, polymers, biodegradable polymers, biodegradable polyesters, starch, polylactic acid starch blends, polylactic acid, polylactic acid-glycolic acid-its copolymers, polydioxanone, cellulose esters, ethyl cellulose, cellulose acetate butyrate, starch esters, starch esteraliphatic polyester blends, modified corn starch, polycaprolactone, polynamylmethacrylate, wood rosin, polyanhydrides, polyvinylalcohol, polyhydroxybutyratevalerate, biodegradable aliphatic polyesters, polyhydroxybutyrate, alkylated naphthalene sulfonate, sodium salt, sodium salt of naphthalene sulfonate condensate, sodium salt of alkyl naphthalene sulfonate, sodium ligno sulfonate, sodium ploycarboxylate, EO/PO block copolymer, phenol sulfonate, sodium methyl oleoyl taurate, styrene acrylic acid copolymer, propyleneoxide-ethyleneoxide-copolymer, polyethylene glycol 2,4,6-tristyrylphenyl ether, tristyrylphenol-polyglycolether-phosphate, tristyrylphenole with 16 moles EO, tristyrylphenol-polyglycolether-phosphate, oleyl-polyglycolether with ethylene oxide, tallow fattyamine polyethylene oxide, nonylphenol polyglycolether with 9-10 moles ethylene oxide and mixture thereof.

31. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the suspending agent for suspo emulsion (SE) is selected from aluminum magnesium silicate, bentonite clay, silica, silicone dioxide, attapulgite clay and mixture thereof.

32. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the antifoaming agent for suspo emulsion (SE) is selected from silicone oil, silicone compound, C10~C20 saturated fat acid compounds, C8~C10 aliphatic alcohols compound, silicone antifoam emulsion, dimethylsiloxane, polydimethyl siloxane, vegetable oil based antifoam, tallow based fatty acids, polyalkyleneoxide modified and mixture thereof.

33. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the preservatives for suspo emulsion (SE) is selected from propionic acid its sodium salt, sorbic acid-its sodium salt, potassium salt, benzoic acid-its sodium salt, p-hydroxy benzoic acid sodium salt, methyl p-hydroxy benzoate, biocide, sodium benzoate, 1,2-benzisothiazoline(2H)-3-one, 2-methyl-4-isothiazolin-3-one, 5-chloro-2-methyl-4-isothiazolin-3-one, potassium sorbate, parahydroxy benzoates and mixture thereof.

34. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the buffering agent for suspo emulsion (SE) is selected from calcium hydroxyapatite, potassium dihydrogen phosphate, sodium hydroxide, carbonated apatite, calcium carbonate, sodium bicarbonate, tricalcium phosphate, calcium phosphates, carbonated calcium phosphates, amine monomers, lactate dehydrogenase, magnesium hydroxide, citric acid and mixture thereof.

35. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the solvent for suspo emulsion (SE) is selected from water, water soluble alcohols and dihydroxy alcohol ethers, water soluble alcohol or lower alcohol -1 to 4 carbon atoms, methanol, ethanol, n-propanol, isopropanol, n-butanol, tert-butanol, macromolecular alcohol, polyethylene glycol, sorbitol, glucitol, dihydroxy alcohol ethers, dihydroxy alcohol alkyl ether, dihydroxy alcohol aryl ethers, dihydroxy alcohol alkyl ether, ethylene glycol methyl ether, diethylene glycol methyl ether, propylene glycol methyl ether, di-propylene glycol methyl ether, ethylene glycol ethyl ether, diethylene glycol ethyl ether, propylene glycol ethyl ether, di-propylene glycol ethyl ether, dihydroxy alcohol aryl ethers includes ethylene glycol phenyl ether, 5 diethylene glycol phenyl ether, propylene glycol phenyl ether, di-propylene glycolphenyl ether, aromatic solvent C-9, hyrdocarbons, n-pentane, hexanes, cyclohexane, methylcyclohexane, heptane, isooctane, benzene, toluene, xylenes, isophorone, ester solvents, methyloleate, dimethylamide, morpholineamide derivatives of C6-C16 fatty acids, mono-alkylene carbonates, ethylene carbonate, propylene carbonate, butylene carbonates, dimethylsulfoxide (DMSO), 2-ethylhexanol, n-butanol, n-alkylpyrrolidones, fatty acid dimethyl esters, fatty acid esters, dibasic esters, aromatic hydrocarbons, aliphatic hydrocarbons, one or more dimethylamides, C8-dimethylamide, C10-dimethylamide, C12-dimethylamide, ethylene glycol, propylene glycol, polyalkylene glycols, aromatic hydrocarbons, methylpyrrolidinone (NMP), dimethylformamide (DMF), dimethylisosorbide (DMI), isophorone, acetophenone, 1,3-dimethyl-2-imidazolidonone, lactate esters, dimethyl, diethylcarbonates, alcohols including methanol, ethanol, iso-propanol, n-propanol, n-butanol, iso-butanol, tert-butanol, methyl L-lactate, 2-ethylhexyl L-lactate, ethyl L-lactate, n-butyl L-lactate, octyl phenol ethoxylates or mixture thereof.

36. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the anti freezing agent for suspo emulsion (SE) is selected from ethylene glycol, propane diols, glycol, monoethylene glycol, diethylene glycol, polypropylene glycol, polyethylene glycol, glycerine, urea, magnesium sulfate heptahydrate, sodium chloride and mixture thereof.

37. A synergistic ternary insecticidal composition as claimed in claim 3, wherein the thickner for suspo emulsion (SE) is selected from thickening, gelling, and anti-settling agents generally fall into two categories is selected from, but not limited to, water-insoluble particulates and water-soluble polymers, clays, silicas, montmorillonite, bentonite, magnesium aluminum silicate, attapulgite, water-soluble polysaccharides, natural extracts of seeds, seaweeds, synthetic derivatives of cellulose, guar gum, locust bean gum, carrageenam, xanthan gum, alginates, methyl cellulose, sodium carboxymethyl cellulose (SCMC), hydroxyethyl cellulose (HEC), modified starches, polyacrylates, polyvinyl alcohol, polyethylene oxide or mixtures thereof.

Dated this on September 10, 2024

Dr. Omkar Rajeshkumar Acharya
Advocate & Patent Agent
For and on the behalf of applicant
IN/PA-4341