DESC:
Title of The Invention
IOT Enabled Histamine Chamber for Assessment of Allergic Activity in Experimental Animals

Field of the Invention
This invention relates to enabled histamine chamber for assessment of allergic activity in experimental animals.

Background of the Invention
US3656456A: An apparatus for indication of moving activity of animals which are disposed in closed space in which at least one of the walls is provided with a number of small capacitor plates which form at least one capacitor in a balanced bridge. When the animals move the dielectric constant of this capacitor is affected and an unbalance voltage is obtained in the bridge. The variations of this voltage are indicated in an indicator connected to the bridge via a derivating network.
US3974798A: A walled enclosure or cage is provided in which laboratory animals may be maintained for observation and evaluation. The floor of the enclosure is provided by a plurality of conductive bar elements that are especially separate and extend across the bottom of the enclosure. Special separation of the bars insulates one from the other and further, space is provided in the floor to remove animal waste, excess food and the like. An electrical resistor is connected between each two adjacent conductive bars and cooperate with the bars to define a resistor network to which a closely controlled feed current is supplied. An animal makes contact with the conductive bars which lowers resistance of the network and produces a voltage change. The resistor network is a.c. coupled to a differential amplifier, and a comparator which receive pulses from capacitors between the network and the amplifier and prepare same for an interface means for a pulse recording system. The amplified pulse may be shaped, divided or the like as required by the recording system. The method of using the present system involves detection of contact between an animal foot and the conductive grid bars, whereupon contact area determines the resistance of the network and a proportional signal is produced therefrom. The signal is then amplified, manipulated to avoid ambient electrical interference, such as an incidental electrical field from line current at 60 Hertz, and/or shaped, divided or the like to provide input to a particular recording system. Raw data from the recording system can then be correlated to locomotor activity of the laboratory animal.

US7882135B2: In this patent a system and method used to assess animal behavior includes a module having sensors that collects a variety of physical and biological data from a test subject. Interpretation of the data is provided to assess the test subject's behavior, neurology, biochemistry and physiology. The module is useful in observing the effects of a drug on the test animal and providing information on the drug's signature. Another advantage is the module's portability that allows it to be used in standard laboratory cages. This portability allows the animal to be tested in its own habitat, that can reduce any erroneous data due to stressing the animal when removed to a test cage. Additionally, the module's design allows for parallel data collection and interpretation from several laboratory animals undergoing different experiments. Multi-dimensional modeling of the test subject based the system's interpretation of the data allows pattern recognition of the drug signature, and predictive drug analysis.

Research Gap: This patent is not applicable in case of Histamine chamber (instrument used for experimental animal). The flow rate or concentration of spray in single eject can be determined by this invention.
None of the prior art indicate above either alone or in combination with one another disclose what the present invention has disclosed. Present invention is the experimental animal activities are conducted for the welfare of society. Conducting the activities, approvals are required by the governing bodies as animals may be sacrificed as per the need of study. This invention will help to reduce the mortality rate of animals, during conducting the allergic activity in histamine chamber.

SUMMARY OF THE INVENTION
This summary is provided to introduce a selection of concepts, in a simplified format, that are further described in the detailed description of the invention.
This summary is neither intended to identify key or essential inventive concepts of the invention and nor is it intended for determining the scope of the invention.
To further clarify advantages and features of the present invention, a more particular description of the invention will be rendered by reference to specific embodiments thereof, which is illustrated in the appended drawings. It is appreciated that these drawings depict only typical embodiments of the invention and are therefore not to be considered limiting of its scope. The invention will be described and explained with additional specificity and detail with the accompanying drawings.
The histamine chamber is used to determine the allergic activities in experimental animals. Fig. 1 reflects that the Histamine chamber (10) have two compartments in it. The animal activity area (11) and the aerosol (13) attached with computing unit (12). The pressure is exerted to the aerosol (13) with the help of rubber bulb (14) and the pressure will be reflected to the pressure reflector (15).
Fig. 2, it is reflected that the nozzle (250) is attached with an actuator (200) with is supported by computing unit. The flow motor (450) is attached which will be responsible be maintain the flow rate (300), a pressure input (350) is also attached with computing unit. The battery is attached for power supply (600) throughout the system. The concentration of flow rate will be reflected in OLED display (500). The data through computing unit will be collected to the APP (550) through Wi-fi Modem (400).
BRIEF DESCRIPTION OF THE DRAWINGS
The illustrated embodiments of the subject matter will be understood by reference to the drawings, wherein like parts are designated by like numerals throughout. The following description is intended only by way of example, and simply illustrates certain selected embodiments of devices, systems, and methods that are consistent with the subject matter as claimed herein, wherein: Fig. 1 reflects that the Histamine chamber (10) have two compartments in it. The animal activity area (11) and the aerosol (13) attached with computing unit (12). The pressure is exerted to the aerosol (13) with the help of rubber bulb (14) and the pressure will be reflected to the pressure reflector (15). Fig. 2, it is reflected that the nozzle (250) is attached with an actuator (200) with is supported by computing unit. The flow motor (450) is attached which will be responsible be maintains the flow rate (300), a pressure input (350) is also attached with computing unit. The battery is attached for power supply (600) throughout the system. The concentration of flow rate will be reflected in OLED display (500). The data through computing unit will be collected to the APP (550) through Wi-fi Modem (400).
The figures depict embodiments of the present subject matter for the purposes of illustration only. A person skilled in the art will easily recognize from the following description that alternative embodiments of the structures and methods illustrated herein may be employed without departing from the principles of the disclosure described herein.
DETAILED DESCRIPTION OF THE INVENTION
The detailed description of various exemplary embodiments of the disclosure is described herein with reference to the accompanying drawings. It should be noted that the embodiments are described herein in such details as to clearly communicate the disclosure. However, the amount of details provided herein is not intended to limit the anticipated variations of embodiments; on the contrary, the intention is to cover all modifications, equivalents, and alternatives falling within the scope of the present disclosure as defined by the appended claims.
It is also to be understood that various arrangements may be devised that, although not explicitly described or shown herein, embody the principles of the present disclosure. Moreover, all statements herein reciting principles, aspects, and embodiments of the present disclosure, as well as specific examples, are intended to encompass equivalents thereof.
The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of example embodiments. As used herein, the singular forms “a",” “an” and “the” are intended to include the plural forms as well, unless the context clearly indicates otherwise. It will be further understood that the terms “comprises,” “comprising,” “includes” and/or “including,” when used herein, specify the presence of stated features, integers, steps, operations, elements and/or components, but do not preclude the presence or addition of one or more other features, integers, steps, operations, elements, components and/or groups thereof.
It should also be noted that in some alternative implementations, the functions/acts noted may occur out of the order noted in the figures. For example, two figures shown in succession may, in fact, be executed concurrently or may sometimes be executed in the reverse order, depending upon the functionality/acts involved.
In addition, the descriptions of "first", "second", “third”, and the like in the present invention are used for the purpose of description only, and are not to be construed as indicating or implying their relative importance or implicitly indicating the number of technical features indicated. Thus, features defining "first" and "second" may include at least one of the features, either explicitly or implicitly.
Unless otherwise defined, all terms (including technical and scientific terms) used herein have the same meaning as commonly understood by one of ordinary skill in the art to which example embodiments belong. It will be further understood that terms, e.g., those defined in commonly used dictionaries, should be interpreted as having a meaning that is consistent with their meaning in the context of the relevant art and will not be interpreted in an idealized or overly formal sense unless expressly so defined herein.
These and other advantages of the present subject matter would be described in greater detail with reference to the following figures. It should be noted that the description merely illustrates the principles of the present subject matter. It will thus be appreciated that those skilled in the art will be able to devise various arrangements that, although not explicitly described herein, embody the principles of the present subject matter and are included within its scope.
The flow rate of histamine solution i.e., the concentration released during spray is not known exactly. Due to which the chance of mortality rate may be high. The IOT enabled technique will helps to estimate the flow rate during every spray and will be reflected in digital display. The experimental animal activities are conducted for the welfare of society. For conducting the activities, approvals are required by the governing bodies as animals may be sacrificed as per the need of study. This invention will help to reduce the mortality rate of animals, during conducting the allergic activity in histamine chamber.

CLAIMS:
1. IOT enabled histamine chamber for assessment of allergic activity in experimental animals’ system is comprises histamine chamber (10) have two compartments, animal activity area (11) and the aerosol (13) attached with computing unit (12); the pressure is exerted to the aerosol (13) with the help of rubber bulb (14) and the pressure will be reflected to the pressure reflector (15).
2. The system, nozzle (250) is attached with an actuator (200) with is supported by computing unit; flow motor (450) is attached which will be responsible be maintains the flow rate (300), a pressure input (350) is also attached with computing unit; battery is attached for power supply (600) throughout the system; the concentration of flow rate will be reflected in OLED display (500) and data through computing unit will be collected to the APP (550) through Wi-fi Modem (400).
3. The system as claimed in claim 1, wherein said histamine chamber (10) have two compartments, animal activity area (11) and the aerosol (13).
4. The system as claimed in claim 1, wherein said computing unit (12); the pressure is exerted to the aerosol (13) with the help of rubber bulb (14) and the pressure will be reflected to the pressure reflector (15).
5. The system as claimed in claim 2, wherein said nozzle (250) is attached with an actuator (200) with is supported by computing unit; flow motor (450) is attached which will be responsible be maintains the flow rate (300).
6. The system as claimed in claim 2, wherein said pressure input (350) is also attached with computing unit; battery is attached for power supply (600) throughout the system.
7. The system as claimed in claim 2, wherein said concentration of flow rate will be reflected in OLED display (500) and data through computing unit will be collected to the APP (550) through Wi-fi Modem (400).