A Thermoresponsive Hydrogel And A Method Of Preparation Thereof

Abstract: The present invention discloses a thermoresponsive hydrogel comprising: a protein component; and a polymer component; wherein the protein component is a mucoadhesive protein and/or collagen; and the protein is cross linked with a polymer, to form a protein-polymer solution that undergoes phase transition from sol-to-gel as the environmental temperature is increased above its Lower critical temperature solution to form a porous hydrogel. The present invention also discloses a method for preparing the thermoresponsive hydrogel. The thermoresponsive hydrogel has pro-angiogenic and pro-innervation properties which can be used for promoting osteoblast activity.

Patent Information

Application #

Filing Date

24 March 2023

Publication Number

39/2024

Publication Type

INA

Invention Field

CHEMICAL

Status

Email

Parent Application

Applicants

Institute of Life Sciences

Institute of Life Sciences, Nalco Square Bhubaneswar-751023, Odisha

Inventors

1. MAMONI DASH

Institute of Life Sciences, Nalco Square, Bhubaneswar-751023, Odisha, India

2. DEBYASHREETA BARIK

Institute of Life Sciences, Nalco Square, Bhubaneswar-751023, Odisha, India

Specification

Description:Please see the attachment , Claims:Please see the attachment

Documents

Application Documents

#	Name	Date
1	202331020916-STATEMENT OF UNDERTAKING (FORM 3) [24-03-2023(online)].pdf	2023-03-24
3	202331020916-Sequence Listing in PDF [24-03-2023(online)].pdf	2023-03-24
4	202331020916-FORM FOR SMALL ENTITY(FORM-28) [24-03-2023(online)].pdf	2023-03-24
5	202331020916-FORM 1 [24-03-2023(online)].pdf	2023-03-24
6	202331020916-EVIDENCE FOR REGISTRATION UNDER SSI(FORM-28) [24-03-2023(online)].pdf	2023-03-24
7	202331020916-EDUCATIONAL INSTITUTION(S) [24-03-2023(online)].pdf	2023-03-24
8	202331020916-DRAWINGS [24-03-2023(online)].pdf	2023-03-24
9	202331020916-DECLARATION OF INVENTORSHIP (FORM 5) [24-03-2023(online)].pdf	2023-03-24
10	202331020916-COMPLETE SPECIFICATION [24-03-2023(online)].pdf	2023-03-24
11	202331020916-FORM 18 [28-03-2023(online)].pdf	2023-03-28
12	202331020916-Proof of Right [18-05-2023(online)].pdf	2023-05-18
13	202331020916-FORM-26 [18-05-2023(online)].pdf	2023-05-18