DESC:
FORM 2
THE PATENTS ACT, 1970
(39 OF 1970)
&
The Patents Rules, 2003
COMPLETE SPECIFICATION
(See section 10; rule 13)

1. Title of the invention – AGROCHEMICAL COMPOSITIONS COMPRISING OF PYMETROZINE AND TRIAZOLE

2. Applicant(s)

(a) NAME: GSP CROP SCIENCE PVT. LTD

(b) NATIONALITY: An Indian Company

(c) ADDRESS: 404, Lalita Complex, 352/3 Rasala Road, Navrangpura,
Ahmedabad-380009, Gujarat, India

3. PREAMBLE TO THE DESCRIPTION

The following specification describes the nature of this invention and the manner in which it is to be performed

FIELD OF THE INVENTION:

The present invention relates to agrochemical compositions comprising of bioactive amount of Pymetrozine along with Triazole, wherein Triazole may be selected from Propiconazole, Tebuconazole, Hexaconazole, Flusilazole or Tricyclazole. The present invention also relates to process for preparing the said compositions comprising Pymetrozine along with a Triazole wherein Triazole may be selected from Propiconazole, Tebuconazole, Hexaconazole, Flusilazole or Tricyclazole and at least one agrochemically acceptable excipient.

BACKGROUND OF THE INVENTION

Pesticides are chemicals that may be used to kill fungus, bacteria, insects, plant diseases, snails, slugs, or weeds among others. These chemicals can work by ingestion or by touch and death may occur immediately or over a long period of time.

Insecticides are chemicals used to control insects by killing them or preventing them from engaging in behaviors deemed undesirable or destructive. They are classified based on their structure and mode of action. Many insecticides act upon the nervous system of the insect (e.g., Cholinesterase (ChE) inhibition) while others act as growth regulators or endotoxins.

Insecticides are agents of chemical or biological origin that control insects. Control may result from killing the insect or otherwise preventing it from engaging in behaviors deemed destructive. Insecticides may be natural or manmade and are applied to target pests in a myriad of formulations and delivery systems. The science of biotechnology has, in recent years, even incorporated bacterial genes coding for insecticidal proteins into various crop plants that deal death to unsuspecting pests that feed on them.

Insecticides are a type of pesticide that is used to specifically target and kill insects. Some insecticides include snail bait, ant killer, and wasp killer.

Insecticides can be classified by many ways based on their function, chemical class, mechanism of action etc. Insecticides can be classified as systemic insecticides, contact insecticides, natural insecticides, plant-incorporated protectants (PIPs), inorganic insecticide and organic insecticide.

The mode of action describes how the pesticide kills or inactivates a pest. It provides another way of classifying insecticides. Mode of action is important in understanding whether an insecticide will be toxic to unrelated species, such as fish, birds and mammals.

Insecticidal classes which covers majority of the insecticides are as below:
Organophosphates and carbamates: Organophosphates target the insect's nervous system. Organophosphates interfere with the enzymes acetylcholinesterase and other cholinesterases, disrupting nerve impulses and killing or disabling the insect. Organophosphate insecticides and chemical warfare nerve agents (such as sarin, tabun, soman, and VX) work in the same way. Organophosphates have a cumulative toxic effect to wildlife, so multiple exposures to the chemicals amplify the toxicity. Carbamate insecticides have similar mechanisms to organophosphates, but have a much shorter duration of action and are somewhat less toxic. Organochlorides: The best-known organochloride, DDT (Dichloro diphenyl trichloroethane), was created by Swiss scientist Paul Müller. For this discovery, he was awarded the 1948 Nobel Prize for Physiology or Medicine. DDT was introduced in 1944. It functions by opening sodium channels in the insect's nerve cells. The contemporaneous rise of the chemical industry facilitated large-scale production of DDT and related chlorinated hydrocarbons. Neonicotinoids: Neonicotinoids are synthetic analogues of the natural insecticide nicotine (with much lower acute mammalian toxicity and greater field persistence). These chemicals are acetylcholine receptor agonists. They are broad-spectrum systemic insecticides, with rapid action (minutes-hours). They are applied as sprays, drenches, seed and soil treatments. Treated insects exhibit leg tremors, rapid wing motion, stylet withdrawal (aphids), disoriented movement, paralysis and death. Imidacloprid may be the most common. Pyrethroids: Pyrethroid pesticides mimic the insecticidal activity of the natural compound pyrethrum. These compounds are nonpersistent sodium channel modulators and are less toxic than organophosphates and carbamates. Compounds in this group are often applied against household pests. Ryanoids: Ryanoids are synthetic analogues with the same mode of action as ryanodine, a naturally occurring insecticide extracted from Ryaniaspeciosa (Flacourtiaceae). They bind to calcium channels in cardiac and skeletal muscle, blocking nerve transmission. Plant-incorporated protectants: Transgenic crops that act as insecticides began in 1996 with BT corn that produces the Cry protein, derived from the bacterium Bacillus thuringiensis, which is toxic to moth larvae such as the European corn borer. The technique has been expanded to include the use of RNA interference RNAi that fatally silences crucial insect genes. RNAi likely evolved as a defense against viruses. Midgut cells in many larvae take up the molecules and help spread the signal. The technology can target only insects that have the silenced sequence, as was demonstrated when a particular RNAi affected only one of four fruit fly species. The technique is expected to replace many other insecticides, which are losing effectiveness due to the spread of pesticide resistance. Fungi serve as the planet's decomposers by breaking down organic material in nature, while many form healthy symbiotic relationships with plants in the soil. Unfortunately some fungi develop parasitic relationships with plants where the plant is harmed making it important to have the proper fungicide to minimize those effects. Fungi are plants which obtain their nutrition from an organic carbon source. The body of the fungus secretes enzymes which degrade the organic substrate on which they are growing and yield smaller entities. These in turn are absorbed into the body of the fungus and are metabolized and provide energy to carry on vital processes. Fungicides can either be contact, translaminar or systemic. Contact fungicides are not taken up into the plant tissue, and protect only the plant where the spray is deposited; translaminar fungicides redistribute the fungicide from the upper, sprayed leaf surface to the lower, unsprayed surface; systemic fungicides are taken up and redistributed through the xylem vessels. Few fungicides move to all parts of a plant. Some are locally systemic, and some move upwardly.

Fungicides also can be classified based upon their chemical composition. Chemically, organic molecules are those that contain carbon atoms in their structure whereas inorganic molecules do not. Many of the first fungicides developed were inorganic compounds based on sulfur or metal ions such as copper, tin, cadmium and mercury that are toxic to fungi. Copper and sulfur are still widely used. Most other fungicides used today are organic compounds and thus contain carbon. The term "organic" as used here is based on chemistry terminology and differs from "organic" used to describe a system of agriculture that strives to be holistic and to enhance agroecosystem health. Fungicides kill fungi by damaging their cell membranes, inactivating critical enzymes or proteins, or by interfering with key processes such as energy production or respiration. Others impact specific metabolic pathways such as the production of sterols or chitin. In recent developments, the newly developed fungicides are unique in that they do not directly affect the pathogen itself. Many of new fungicides elicit a response from the host plant known as "systemic acquired resistance" (SAR). These SAR inducers basically mimic chemical signals in plants that activate plant defense mechanisms such as the production of thicker cell walls and anti-fungal proteins. The utility of SAR inducers, however, has been limited so far since many pathogens are capable of over-powering such defenses.

Fungicide resistance is a stable, heritable trait that results in a reduction in sensitivity to a fungicide by an individual fungus. This ability is obtained through evolutionary processes. Fungicides with single-site mode of action are at relatively high risk for resistance development compared to those with multi-side mode of action. Most fungicides being developed today have a single-site mode of action because this is associated with lower potential for negative impact on the environment, including non-target organisms.

When fungicide resistance results from modification of a single major gene, pathogen subpopulations are either sensitive or highly resistant to the pesticide. Resistance in this case is seen as complete loss of disease control that cannot be regained by using higher rates or more frequent fungicide applications. This type of resistance is commonly referred to as "qualitative resistance."

The control of phytopathogenic fungi is of great economic importance since fungal growth on plants or on parts of plants inhibits production of foliage, fruit or seed, and the overall quality of a cultivated crop.

Pymetrozine was first disclosed in US4931439 and US4996325.Pymetrozine is chemically known as (E)-4,5-dihydro-6-methyl-4-(3-pyridylmethyleneamino)-1,2,4-triazin-3(2H)-one and having chemical structure as below;

The mode of action of pymetrozine in insects has not been precisely determined biochemically, but it may involve effects on neuroregulation or nerve-muscle interaction. Physiologically, it appears to act by preventing these insects from inserting their stylus into the plant tissue.

Pymetrozine is selective against Homoptera, causing them to stop feeding. Pymetrozine is used in control of aphids and whitefly in vegetables, potatoes, ornamentals, cotton, deciduous and citrus fruit, tobacco, hops; both juvenile and adult stages are susceptible and also control plant hoppers in rice. Pymetrozine application rates vary from 150 g/ha on potatoes to 200-300 g/ha on ornamentals, tobacco and cotton; 10-30 g/hl on vegetables, fruit and hops. Pymetrozine is available in market with DP; GR; WP; WG formulation.

Propiconazole and its synthesis as well as its antifungal properties are described in U.S. Pat. No. 4,079,062. Propiconazole as mentioned hereinabove is the generic name of the compound 1-[[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-yl]methyl]-1H-1,2,4-triazole, which compound may be represented by below given structure.

Propiconazole is a steroid demethylation (ergosterol biosynthesis) inhibitor. Propiconazole is a systemic foliar fungicide with protective and curative action, with translocation acropetally in the xylem. At labeled application rates, Propiconazole controls numerous diseases caused by, for example, Crx.'hhoboIns swims, Erysiphegraminis, Leptosphaerianodonon, Puccinia spp., Pyrenophorateres, Pyrenophoratrifici-repentis, Rhynchosporiumsem and Septoria spp. on cereals; Alycosphaerellamusicola and Mycosphaerella Monisvar, difformis in bananas; Sclerotiniahomoeocarpa, Rhizoctonia so/an:, Puccinia spp., .Erysiphegraminis in turf; Rhizocioniasolani, Hehninthosporiumoryzae and dirty panicle complex in rice; HennLelavastatrix in coffee; Cercospora spp. in peanuts; Monihnia spp., Podosphaera spp., Sphaerotheca spp. and Tranzwhelia spp. in stone fruit; and Helminthosporium spp. in maize. Propiconazole is a substantially water-insoluble liquid at 20 C.

Tebuconazole compound, its synthesis as well as its antifungal properties are described in EP-A-0,040,345 and EP-A-0,052,424. Tebuconazole as mentioned hereinabove is the generic name of the compound a-[2-(4-chlorophenyl)ethyl]-a-(1,1-dimethylethyl)-1H-1,2,4-triazol-1-ethanol, which compound may be represented by below structure;

It is well known that Tebuconazole is a substance with fungicidal activity belonging to the chemical family of the triazoles, endowed with a particularly high level of activity against Microdochiumnivale (pink snow mould), Sclerotiniahomeocarpa (dollar spot), Rhizoctoniasolani, (rhizoctoniosis), Sphaerothecapannosa (rose powdery mildew), Diplocarponrosae (rose black spot), Phragmidiummucronatum (rose rust), Pucciniaspp (various rusts) and Oidiumspp (various powdery mildews).Over time, many Tebuconazole-based formulations have been developed. All the formulations present in the market have been conceived to be applied through a liquid vehicle, for example an aqueous solution or a solution containing water. Examples of formulations containing Tebuconazole can be the formulations called WP (wettable powder), the formulations called SC (concentrated suspension); the formulations called WG (water dispersible granules) or formulations called SE (suspoemulsions). The known formulations described above, based on Tebuconazole, are formulations that require pre-dilution (or dispersion) in an aqueous vehicle before being applied. The Tebuconazole present in said liquid formulations or dispersions is applied through the aqueous vehicle by spraying or atomizing said formulations using special sprayers or atomizers.

Chemical name of Hexaconazole is (RS)-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)hexan-2-ol and chemical formula is: C14H17C12N30, Hexaconazole is represented by below structure:

Hexaconazole is a triazole fungicide. Hexaconazole is steroid demethylation inhibitor, especially against fungi and Basidiomycotina Ascomycota subphylum disease caused by a broad spectrum of protection and treatment.

Flusilazole is the common name for bis(4-fluorophenyl)methyl(1H-2,4-triazole-1-ylmethyl)silane. Flusilazole is represented by below structure;

Flusilazole is mainly biosynthesis cell membrane damage bacteria cell membrane. Flusilazole is preventive and curative fungicide effective against many pathogens (Ascomycetes, Basidiomycetes and Deuteromycetes). Flusilazole is more effectively used on crops, such as: apples (Venturia inaequalis, Podosphaera leucotricha); peaches (Sphaerotheca pannosa, Monilia laxa); cereals (all major diseases); grapes (Uncinula necator, Guignardia bidwellii); sugar beet (Cercospora beticola, Erysiphe betae); maize (Helminthosporium turcicum); sunflowers (Phomopsis helianthi); oilseed rape (Pseudocercosporella capsellae, Pyrenopeziza brassicae); bananas (Mycosphaerellaspp.).

Tricyclazole, 5-methyl-l,2,4-triazolo(3,4-b)benzothiazole, is a systemic fungicide for the control of Piriculariaoryzae, the causative organism of rice blast. Tricyclazole is described and claimed in United States Patent No. 4,064,261, issued 20 September, 1977, in Japanese Patent No. 984,228, issued 22 January, 1980, in Korean Patent No. 5,132, issued 7 August, 1976, and in Taiwanese Patent No. N19543, issued 13 October, 1977. Tricyclazole is represented by below structure;

The fungicidal action of triazoles is mainly attributed to their ability to inhibit cytochrome P450 dependent enzyme lanosterol 14 a-demethylase. Lanosterol 14 a-demethylase is necessary for the conversion of lanosterol to ergosterol which is an essential component of fungal cell membrane. Triazoles may exhibit other direct effects on cell membrane fatty acids and can inhibit cytochrome P450 dependent enzymes of the fungal respiration chain. Triazole antifungal agents to cytochrome P450 differs, resulting in variations in antifungal activity, toxicity of the agents and the relative likely hood of drug interactions with other cytochrome P450 metabolized drugs. Cytochromes P450 are ubiquitous heme containing proteins that are found throughout the plant and animal kingdom and play a crucial role in the synthesis of steroidal hormones in mammals. Any interference in the synthesis of sex steroidal hormones will obviously affect the reproductive performance. Propiconazole, Tebuconazole, Hexaconazole, Flusilazole or Tricyclazole is a triazole fungicide that is widely being used in agricultural and horticultural practices. Propiconazole, Tebuconazole, Hexaconazole, Flusilazole or Tricyclazole is effective against Ascomycetes, Basidiomycetes and semi-known diseases caused by bacteria, diseases especially Basidiomycetes and Ascomycetes, such as caused by powdery mildew, rust, scab, leaf spot, anthracnose, which are superior protection and eradicate effect.

The main concern with the use of pesticide is the development of resistance by the pests for that particular pesticide and at the end one has to apply more concentrated formulation of the pesticide. The high amount of pesticide may results in the toxicity to human beings as well as has bad effect on environment.

Previously people have tried many alternatives and option to overcome this problem and as a result developed poly mixture of pesticide, use of non-toxic ingredients and developing synergistic formulations which provides effective amount of the pesticide and at the required part only.

However the use of poly mixture containing large number of pesticides poses a problem in many was like preparing formulation of multiple pesticides with different chemical properties and behavior and physical properties. It also creates challenge for formulator in term of compatibility and stability of all the pesticide along with used excipients in the formulation.

US 6,486,157 relates to a novel method of controlling pests in and on transgenic crops of useful plants with pymetrozine; profenofos; a benzoylurea-derivative, especially lufenuron; or a carbamate-derivative, especially fenoxycarb.

US 7,192,905 disclose a combination of a cytochrome P450 monooxygenase inducer with an organophosphate pesticide (insecticide or acaracide) provides effective control of ticks and flies, particularly against organophosphate-resistant strains of the ticks and flies. In use, a pesticidally effective amount of a composition of the cytochrome P450 monooxygenase inducer and organophosphate pesticide is applied to the locus of the targeted tick or fly.

US7635404 discloses a composition that is an heterogeneous blend of fertilizer granules and highly absorbent cellulosic granules carrying one or more active principle.

WO03/045877 discloses a formulation comprising fertilizers and pesticides, prepared in the form of micro-granules.

WO2008/014185 discloses a controlled release granule comprising a solid substrate, pesticide and oil, the pesticide and oil being distributed throughout the granule. Optionally, the granules may further comprise a fertilizer material.

GB2238960 discloses granular formulations of a phosphite fungicide in the presence of a wetting agent and a dispersing agent on a support. Such formulations are supposed to decrease the production of dust, to increase the stability, rendering easier and less toxic the handling and the measuring of the pesticide. Triazole fungicides are mentioned as possible partner in the composition for the phosphite. The granules are suspended in water.

WO2013/002299 discloses an agricultural and horticultural insecticide composition containing flubendiamide and Tolfenpyrad as active ingredients and a utilization method therefore characterized in that insects or plants infested with the insects or the surrounding land or cultivation carriers where the plants are grown are treated with an effective dose of the agricultural and horticultural insecticide composition containing flubendiamide and Tolfenpyrad as active ingredients.

Indian patent application 2365/KOLNP/2006 describes a ternary fungicidal mixtures comprising, as active components, 1) the triazolopyrimidine derivative of the formula l, 5-chloro-7-(4-methylpiperidin-1-yl)-6-(2,4,6-trifluorophenyl)-[1,2,4]triazolo[1,5-a]pyrimidine and 2) a strobilurin derivative II, selected from among the compounds pyraclostrobin and orysastrobin and 3) a fungicidally active compound III selected from the group consisting of acylalanines, amine derivatives, anilinopyrimidines, antibiotics, azoles, dicarboximides, dithiocarbamates, copper fungicides, nitrophenyl derivatives, phenylpyrroles, sulfenic acid derivatives, cinnamides and analogs and anilazine, benomyl, boscalid, carbendazim, carboxin, oxycarboxin, cyazofamidjdazomet, dithianon, famoxadone, fenamidone, fenarimol, fuberidazole, flutolanil, furametpyr, isoprothiolane, mepronil, nuarimol, picobenzamid, probenazole, proquinazid, pyrifenox, pyroquilon, quinqxyfen, silthiofam, thiabendazole, thifluzamide, thiophanate-methyl, tiadinil; tricyclazole, triforine, sulfur, acibenzolar-S-methyl, benthiavalicarb, carpropamid, chlorothalonil, cyflufenamid, cymoxanil, dazorhet, diclomezin, diclbcymet, diethofencarb, edifenphos, ethaboxam, fenhexamid, fentin acetate, fenoxanil, ferimzone, fluazinam, phosphorous acid, fosetyl, fosetyl-aluminum, iprovalicarb, hexachlorobenzene, metrafenon, pencycuron, propamocarb, phth'alide, toloclofos-methyl, quintozene and zoxamide; in a synergistically effective amount, methods for controlling phytopathogenic harmful fungi using mixtures of the compounds 1 and II and III with a fungicidally active compound III and the use of the compounds 1 and II with III for preparing such mixtures, and also compositions comprising these mixtures.

However still there is a need for a composition of specific pesticide and/or fungicides which overcomes some of the existing problems and can be prepared easily without much complex manufacturing process.

The objective of the present invention is that time of pest appearance i.e. insects and fungal diseases are the same; hence such compositions would have dual benefit. In addition the mixture will significantly reduce labour dependence and costs.

SUMMARY OF THE INVENTION

The present invention relates to an agrochemical composition which comprise of bioactive amounts of Pymetrozine along with a Triazole wherein Triazole may be selected from Propiconazole, Tebuconazole, Hexaconazole, Flusilazole or Tricyclazole with at least one inactive excipient.

Further the present invention also relates to process for preparing the agrochemical compositions comprising of bioactive amounts of Pymetrozine and Triazole with one or more inactive excipients.

The present invention also relates to agrochemical compositions comprising Pymetrozine along with a Triazole, wherein Triazole may be selected from Propiconazole, Tebuconazole, Hexaconazole, Flusilazole or Tricyclazole, wherein the ratio of Pymetrozine to Propiconazole is 1 : 20 to 20 : 1 and Pymetrozine to Tebuconazole is 1 : 20 to 20 : 1, Pymetrozine to Hexaconazole is 1 : 20 to 20 : 1 , Pymetrozine to Flusilazole 1 : 20 to 20 : 1 and Pymetrozine to Tricyclazole is 1 : 20 to 20 : 1.

Further the present invention also relates to the process for preparing the said agrochemical compositions of Pymetrozine along with a Triazole and at least one agrochemically acceptable excipient.

DETAILED DESCRIPTION OF THE INVENTION

The present invention provides agrochemical compositions comprising Pymetrozine along with a Triazole and at least one agrochemically acceptable excipient.

The present invention also provides agrochemical composition comprising of bioactive amounts of Pymetrozine and Triazole with one or more inactive excipients.

"Bioactive amounts” as mentioned herein means that amount which, when applied treatment of crops, is sufficient to effect such treatment.

The insecticidal and/or fungicidal composition can be classified as below:

a) Dry - Sprayable

a.1) WP – Wettable powders:
A solid pesticide formulation – micronized to powder form and typically applied as suspended particles after dispersion in water.

a.2) WG or WDG – Water dispersible granule:
A pesticidal formulation consisting of granules to be applied after disintegration and dispersion in water. Water dispersible granules can be formed by a) agglomeration, b) spray drying, or c) extrusion techniques. It can also be termed as water soluble granules (WSG) or soluble granules (SG).

b) Liquid Sprayable
b.1) SL – Soluble Concentrate:
A soluble concentrate is in powder form intended for dilution with water or directly in solution from. In both the case, the end result will be clear solution of the insecticide in the water without any visible un-dissolved particles.

b.2) SC – Suspension Concentrate
A stable suspension of solid pesticide(s) in a fluid usually intended for dilution with water before use. For a good formulation or ideal SC formulation, it should be stable and do not sediment over time.

b.3) EC – Emulsifiable Concentrate
A solution of a pesticide with emulsifying agents in a water insoluble organic solvent which will form an emulsion when added to water. In most of the case it is oil in water type emulsion to make it easy for application. EC formulation should be storage stable without any visible cracking of emulsion.

b.4) ME – Microemulsion
A solution of a pesticide with emulsifying agents in a water insoluble organic solvent which will form a solution/emulsion when added to water. The difference between EC and ME is the particle size of the actives in the final form.

b.5) OD – Oil Dispersion
Oil dispersions (OD) are one type of liquid formulation which is stable suspensions of active ingredients in a water-immiscible fluid which may contain other dissolved active ingredients and is intended for dilution with water before use.

b.6) CS – Capsule Suspension
Suspension of micro-encapsulated active ingredient in an aqueous continuous phase, intended for dilution with water before use.

b.7) SE- Suspension emulsion
A suspension emulsion or suspo emulsion (SE) consists of an organic phase with a dissolved active ingredient and an aqueous suspension phase, in which the active ingredient is dispersed in water.

b.8) Dispersible concentrate (DC)
Dispersible concentrate (DC) is a liquid homogeneous formulation to be applied as a solid dispersion after dilution in water. There are many formulations which contains the part characteristics of EC and part characteristics of DC.

c) Dry – Spreadable Granule
Dry spreadable granules are dry granules which can be applied with a dry spreader to a target area and later when such granules get exposed to water via, for example, rain or irrigation, will not only readily disintegrate, but actively spread on solid substrates so as to achieve disintegration area diameter to original granule diameter ratios.

Dry spreadable granules should possess good hardness and an ability to maintain integrity upon normal, commercial handling in a dry spreading operation and yet be capable of quickly disintegrating or scattering upon what may be a minimal exposure to water, such as, for example, a light rain.

d) GR – Soil applied Granule on inert or fertilizer carrier
This formulation is in the form of granules which can be applied on inert carrier or the carrier which is fertilizer.

e) Mixed formulation

e.1) ZC Formulation (Mix of CS and SC)
“ZC formulation” is the international denominations adopted by the FAO (Food and Agricultural Organization of the United Nations) to designate "stable aqueous suspension of microcapsules and solid fine particles"

ZC is a mixed formulation of CS and SC and is a stable aqueous suspension of microcapsules and solid fine particles, each of which contains one or more active ingredients. The formulation is intended for dilution into water prior to spray application. Formulating the active ingredients together eliminates the need for tank mixing, which can lead to incompatibility, and facilitates control of a wider range of pests with fewer applications. Like other aqueous liquid formulations, ZC formulations are easy to handle and measure, dust free, non-flammable and offer good miscibility with water.

One or more of the active ingredients is encapsulated for various purposes, such as to increase the residual biological activity, or to reduce the acute toxicity, or to obtain a physical or chemically stable water-based formulation. The purpose determines whether the “free” active ingredient and the “release rate” are relevant properties of a specific product.

The term WDG, DG, WSG and SG are synonyms and can be used inter changeably and convey the same meaning.

The term composition and formulation are synonyms and can be used inter changeably and convey the same meaning.

Composition of the present invention can be in any of the form described above, preferblay selected from Suspo emulsion (SE), Suspension concentrate (SC), Zeon Concentrate (ZC), Wettable powders (WP), Water dispersible granules or wet table granules (WDG or WG).

Pymetrozine along with a Triazole, wherein one or more Triazole may be selected from Propiconazole, Tebuconazole, Hexaconaxole, Flusilazole or Tricyclazole which are active ingredient for the present composition are present in ratio of 1: 20 to 20: 1. Preferably thea ratio of Pymetrozine and a Triazole, wherein Triazole may be selected from Propiconazole, Tebuconazole, Hexaconazole, Flusilazole or Tricyclazole is 1:5 to 5:1.

The agrochemical composition of Pymetrozine along with a Triazole, wherein Triazole may be selected from Propiconazole, Tebuconazole, Hexaconazole, Flusilazole or Tricyclazole is effective for management of mixed infestation of various sucking insects and fungal diseases in following crops;
Cotton (Gossypium spp.), Jute (Corchorus oliotorus), Paddy (Oryza sativa), Wheat (Triticum aestavum), Barley (Hordeum vulgare), Maize (Zea mays), Sorghum (Sorghum bicolor), Ragi (Eleusine coracana), Pearl millet (Pennisetum glaucum), Sugarcane (Saccharum officinarum) , Sugarbeet (Beta vulgaris), Soybean (Glycin max), Peanut (Arachis hypogaea), Sunflower (Helianthus annuus) , Mustard (Brassica juncea), Rape seed (Brassica napus), Linseed (Linum usitatissimum), Sesame (Sesamum indicum), Castor (Ricinus communis), Green gram (Vigna radiate), Black gram (Vigna mungo), Chickpea (Cicer aritinum), Cowpea (Vigna unguiculata), Redgram (Cajanus cajan), Frenchbean (Phaseolus vulgaris), Indian bean (Lablab purpureus), Horse gram (Macrotyloma uniflorum), Field pea (Pisum sativum), Cluster bean (Cyamopsis tetragonoloba), Lentils (Lens culinaris), Brinjal (Solanum melongena), Cabbage (Brassica oleracea var. capitata), Cauliflower (Brassica oleracea var. botrytis), Okra (Abelmoschus esculentus) , Onion (Allium cepa L.), Tomato (Solanum lycopersicun) , Potato (Solanum tuberosum) , Sweet potato (Ipomoea batatas), Chilly (Capsicum annum), Garlic (Allium sativum), Cucumber (Cucumis sativus) and Melons (Cucumis melo), Radish (Raphanus sativus), Carrot (Dacus carota subsp. sativus), Turnip (Brassica rapa subsp rapa), Apple (Melus domestica), Banana (Musa spp.), Citrus groups (Citrus spp.), Grape (Vitis vinifera), Guava (Psidium guajava), Litchi (Litchi chinensis), Mango (Mangifera indica), Papaya (Carica papaya), Pineapple (Ananas comosus), Pomegranate (Punica granatum) , Sapota (Manilkara zapota), Tea (Camellia sinensis), Coffea (Coffea Arabica), Turmeric (Curcuma longa), Ginger (Zingiber officinale), Cumin (Cuminum cyminum), Fenugreek (Trigonella foenum-graecum), Fennel (Foeniculum vulgare), Coriander (Coriandrum sativum), Ajwain (Trachyspermum ammi), Psyllium (Plantago ovate), Black Pepper (Piper nigrum), Stevia (Stevia rebaudiana), Safed musli (Chlorophytum tuberosum), Drum stick (Moringa oleifera), Coconut (Coco nucifera), Mentha ( Mentha spp.), Rose (Rosa spp.), Jasmine (Jasminum spp.), Marigold ( Tagetes spp.), Common daisy (Bellis perennis), Dahlia (Dahlia hortnesis).
Preferbaly the agrochemical composition of the present invention can be used for Cotton (Gossypium spp.), Paddy (Oryza sativa), Wheat (Triticum aestavum), Barley (Hordeum vulgare), Maize (Zea mays), Sorghum (Sorghum bicolor), Pearl millet (Pennisetum glaucum), Sugarcane (Saccharum officinarum) , Sugarbeet (Beta vulgaris), Soybean (Glycin max), Peanut (Arachis hypogaea), Sunflower (Helianthus annuus) , Mustard (Brassica juncea), Rape seed (Brassica napus), Linseed (Linum usitatissimum), Sesame (Sesamum indicum), Green gram (Vigna radiate), Black gram (Vigna mungo), Chickpea (Cicer aritinum), Cowpea (Vigna unguiculata), Redgram (Cajanus cajan), Frenchbean (Phaseolus vulgaris), Indian bean (Lablab purpureus), Horse gram (Macrotyloma uniflorum), Field pea (Pisum sativum), Cluster bean (Cyamopsis tetragonoloba), Lentils (Lens culinaris), Brinjal (Solanum melongena), Cabbage (Brassica oleracea var. capitata), Cauliflower (Brassica oleracea var. botrytis), Okra (Abelmoschus esculentus) , Onion (Allium cepa L.), Tomato (Solanum lycopersicun) , Potato (Solanum tuberosum) , Sweet potato (Ipomoea batatas), Chilly (Capsicum annum), Garlic (Allium sativum), Cucumber (Cucumis sativus) and Melons (Cucumis melo), Radish (Raphanus sativus), Carrot (Dacus carota subsp. sativus), Turnip (Brassica rapa subsp rapa), Apple (Melus domestica), Banana (Musa spp.), Citrus groups (Citrus spp.), Grape (Vitis vinifera), Guava (Psidium guajava), Litchi (Litchi chinensis), Mango (Mangifera indica), Papaya (Carica papaya), Pineapple (Ananas comosus), Pomegranate (Punica granatum) , Sapota (Manilkara zapota), Tea (Camellia sinensis), Coffea (Coffea Arabica), Turmeric (Curcuma longa), Ginger (Zingiber officinale), Cumin (Cuminum cyminum), Fennel (Foeniculum vulgare), Coriander (Coriandrum sativum), Black Pepper (Piper nigrum), Stevia (Stevia rebaudiana), Safed musli (Chlorophytum tuberosum), Rose (Rosa spp.), Jasmine (Jasminum spp.), Marigold ( Tagetes spp.), Common daisy (Bellis perennis), Dahlia (Dahlia hortnesis), Gerbera.

The agrochemical composition of Pymetrozine along with a Triazole, wherein Triazole may be selected from Propiconazole, Tebuconazole, Hexaconazole, Flusilazole or Tricyclazole is used to control the insects-pests belongs to the order Hemiptera, for example, Apple Mealy bug (Phenococcus aceris), bean aphid (Aphis fabae), black citrus aphid (Toxoptera aurantii), citrus black scale (Saissetia oleae), cabbage aphid (Brevicoryne brassicae, Lipaphis erysimi), citrus red scale (Aonidiella aurantii), citrus mealybug (Planococcus citri), corn leaf aphid (Rhopalosiphum maidis), cotton aphid (Aphis gossypii), cotton leaf hoppers (Amrasca biguttula), cotton mealy bug (Planococcus spp. And Pseudococcus spp.), cotton stainer (Dysdercus suturellus), cotton whitefly (Bemisia tabaci), cowpea aphid (Aphis crassivora), grain aphid (Sitobion avenae), golden glow aphid (Uroleucon spp.), grape mealybug (Pseudococcus maritimus), green peach aphid (Myzus persicae), greenhouse whitefly (Trialeurodes vaporariorum)spp., papaya mealy bug (Pracoccus marginatus), pea aphid (Acyrthosiphon pisum), sugarcane mealybug (Saccharicoccus sacchari), potato aphid (Myzus persicae), potato leaf hopper (Empoasca fabae), rice leafhopper (Nephotettix nigropictus), rice brown plant hopper (Nilaparvata lugen), rice white backedplant hopper ( sweetpotato whitefly ( Bemisia tabaci), tarnished plant bug (Lygus lineolaris), wooly apple aphid (Eriosoma lanigerum), yellow scale (Aonidiella citrine),order Lepidoptera, army worm (Mythimna unipuncta), asiatic rice borer (Chilo suppressalis), bean pod borer (Maruca vitrata), beet armyworm (Spodoptera exigua), black cutworm (Agrotis ipsilon), bollworm (Helicoverpa spp.),cabbage looper (Trichoplusia ni), codling moth (Cydia pomonella), croton caterpillar (Achea janata), diamond backmoth (Plutella xylostella), cabbage worm (Pieris rapae), pink bollworm (Pectinophora gossypiella), sugarcane borer (Diatraea saccharalis), tobacco budworm (Heliothis virescens), tomato fruitworm (Helicoverpa zea), velvet bean caterpillar (Anticarsia gemmatalis), yellow stem borer (SCirpophaga incertulas), spotted bollworm (Earias vittella), rice leaffolder (Cnaphalocrocis medinalis), pink stem borer (Sesamia spp.), tobacco leafeating caterpillar (Spodoptera litura), ; from the order Coleoptera, for example, apple twig borer (Amphicerus spp.), corn root worm (Diabrotica virgifera), cucumber beetle (diabrotica balteata), boll weevil (Anthonomus grandis), grape flea beetle (Altica chalybea), grape root worm (Fidia viticola), grape trunk borer (Clytoleptus albofasciatus), radish flea beetle (Phyllotreta armoraciae), maize weevil (Sitophilus zeamais), northern corn rootworm (Diabrotica barberi), rice water weevil (Lissorhoptrus oryzophilus; from the order Orthoptera, for example, Gryllotalpa spp., Locusta spp., and Schistocerca is spp.; from the order Thysanoptera, for example, Frankliniella spp., Thrips palmi, Thrips tabaci and Scirtothrips dorsalis; from the order Heteroptera, for example, Dysdercus spp., Leptocorisa spp., from the order Hymenoptera, for example, Solenopsis spp. ; from the order Diptera, for example, Antherigona soccata, Dacus spp., Liriomyza spp., Melanagromyza spp., from the order Acarina, for example, Aceria mangiferae, Brevipalpus spp., Eriophyes spp., Oligonychus mangiferus, Oligonychus punicae, Panonychus citri, Panonychus ulmi, Polyphagotarsonemus latus, Tarsonemus spp., Tetranychus urticae, Tetranychus cinnabarinus.
Preferbaly the agrochemical composition of the present invention is effective against pastes selected from Apple Mealy bug (Phenococcus aceris), bean aphid (Aphis fabae), black citrus aphid (Toxoptera aurantii), citrus black scale (Saissetia oleae), cabbage aphid (Brevicoryne brassicae, Lipaphis erysimi), citrus red scale (Aonidiella aurantii), citrus mealybug (Planococcus citri), corn leaf aphid (Rhopalosiphum maidis), cotton aphid (Aphis gossypii), cotton leaf hoppers (Amrasca biguttula), cotton mealy bug (Planococcus spp. And Pseudococcus spp.), cotton stainer (Dysdercus suturellus), cotton whitefly (Bemisia tabaci), cowpea aphid (Aphis crassivora), grain aphid (Sitobion avenae), golden glow aphid (Uroleucon spp.), grape mealybug (Pseudococcus maritimus), green peach aphid (Myzus persicae), greenhouse whitefly (Trialeurodes vaporariorum)spp., Mango hopper (Amtritodus atkinsoni, Idioscopus spp.), papaya mealy bug (Pracoccus marginatus), pea aphid (Acyrthosiphon pisum), sugarcane mealybug (Saccharicoccus sacchari), potato aphid (Myzus persicae), potato leaf hopper (Empoasca fabae), green rice leafhopper (Nephotettix cincticeps & Nephotettix virescens, Nephotettix nigropictus), rice brown plant hopper (Nilaparvata lugen), rice white backed plant hopper, sweetpotato whitefly ( Bemisia tabaci), tarnished plant bug (Lygus lineolaris), wooly apple aphid (Eriosoma lanigerum), yellow scale (Aonidiella citrine), Frankliniella spp., Thrips palmi, Thrips tabaci and Scirtothrips dorsalis, Dysdercus spp., Leptocorisa spp and fungus selected from Acremonium, Alternaria, Ascochyta tritici, Aspergillus, Blumeria, Botryotinia, Botrytis, Botryodiplodia, Cercospora, Cephalosporium, Choanephora, Cladosporium spp., Claviceps spp., Colletotrichum spp., Curvularia, Didymella, Drechslera, Erysiphe, Fusarium, Glomerella, Helminthosporium, Leveillula, Lasiodiplodia, Macrophomina, Microdochium, Monilinia, Mycosphaerella, Oidiopsis, Puccinia, Phoma, Phytophthora, Phakopsora, Phomopsis sp., Plasmopara viticola, Pythium, Pyricularia, Pyrenophora, Physoderma maydis, Peronosclerospora, Rhizopus, Ramularia, Rhizoctonia, Sarocladium, Sclerotinia, Septoria, Stemphylium, Tilletia tritici, Typhula, Uncinula necator, Urocystis spp., Ustilago tritici, Ustilaginoidea, Venturia inaequalis, Verticillium.
Furtehr as per one embodiment of the present invention, agrochemical composition of the present invention can be used for the control of below mentioned diseases;
Diseases of Wheat:
Alternaria leaf blight Alternaria triticina, Anthracnose Colletotrichum graminicola,Ascochyta leaf spot Ascochyta tritici, Aureobasidium decay Microdochium bolleyi, Black head molds (sooty molds) Alternaria spp., Cladosporium spp., Epicoccum spp., Sporobolomyces spp., Stemphylium spp., Common bunt/ stinking smut Tilletia tritici,Common root rot Bipolaris sorokiniana, Cottony snow mold Coprinus psychromorbidus, Crown rot (foot rot, seedling blight, dryland root rot) Fusarium spp., Fusarium pseudograminearum, Fusarium graminearum, Fusarium culmorum,Dilophospora leaf spot Dilophospora alopecuri, Downy mildew = crazy top Sclerophthora macrospora, Dwarf bunt Tilletia controversa,Ergot Claviceps purpurea, Eyespot = foot rot, Tapesia yallundae, False eyespot Gibellina cerealis,Flag smut Urocystis agropyri, Foot rot Fusarium spp., Karnal bunt = partial bunt Tilletia indica =Neovossia indica, Leaf rust = brown rust Puccinia triticina,Puccinia recondite,Leptosphaeria leaf spot Phaeosphaeria herpotrichoides = Leptosphaeria herpotrichoides,Loose smut Ustilago tritici,Microscopica leaf spot Phaeosphaeria microscopica, Phoma spot Phoma spp., Pink snow mold = Fusarium patch Microdochium nivale,Platyspora leaf spot Clathrospora pentamera,Powdery mildew Erysiphe graminis, Blumeria graminis,Pythium root rot Pythium aphanidermatum, Pythium arrhenomanes, Pythium graminicola, Pythium myriotylum,Rhizoctonia root rot Rhizoctonia solani, Scab = head blight Fusarium graminearum, Sclerotinia snow mold = snow scald Sclerotinia borealis,Sclerotium wilt Sclerotium rolfsii,Septoria blotch Septoria tritici,Sharp eyespot Rhizoctonia cerealis, Snow rot Pythium spp., Speckled snow mold = gray snow mold or Typhula blight Typhula idahoensis,Spot blotch Bipolaris sorokiniana,Stagonospora blotch Phaeosphaeria avenaria, Stagonospora avenae, Septoria avenae, Septoria nodorum , Stem rust = black rust Puccinia graminis,Storage molds Aspergillus spp., Penicillium spp., Stripe rust = yellow rust Puccinia striiformis,Take-all Gaeumannomyces graminis,Tan spot = yellow leaf spot, red smudge Pyrenophora tritici-repentis, Drechslera tritici-repentis,Tar spot Phyllachora graminis.
Diseases of Rice:
Aggregate sheath spot Ceratobasidium oryzae (anamorph: Rhizoctonia oryzae-sativae), Black kernel Curvularia lunata, Blast (leaf, neck [rotten neck], nodal and collar) Pyricularia grisea=P.oryzae,Brown spot Cochliobolus miyabeanus (anamorph: Bipolaris oryzae),Crown sheath rot Gaeumannomyces graminis,Downy mildew Sclerophthora macrospora, Eyespot Drechslera gigantean,False smut Ustilaginoidea virens,Kernel smut Tilletia barclayana =Neovossia horrid, Leaf smut Entyloma oryzae, Leaf scald Microdochium oryzae, Narrow brown leaf spot Cercospora janseana, Pecky rice (kernel spotting) Damage by many fungi including Cochliobolus miyabeanus, Curvularia spp., Fusarium spp., Microdochium oryzae, Sarocladium oryzae, Root rots Fusarium spp., Pythium spp., P. dissotocum, P. spinosum,Seedling blight Cochliobolus miyabeanus, Curvularia spp., Fusarium spp., Rhizoctonia solani, Sclerotium rolfsii,Sheath blight Thanatephorus cucumeris (anamorph: Rhizoctonia solani), Sheath rot Sarocladium oryzae = Acrocylindrium oryzae, Sheath spot Rhizoctonia oryzae, Stackburn (Alternaria leaf spot) Alternaria padwickii, Stem rot Magnaporthe salvinii= Sclerotium oryzae, Water-mold (seed-rot and seedling disease) Achlya conspicua, A. klebsiana, Fusarium spp., Pythium spp., P. dissotocum, P. spinosum.
Diseases of Corn or Maize : Anthracnose leaf blight and anthracnose stalk rot Colletotrichum graminicola, Aspergillus ear and kernel rot Aspergillus flavus, Banded leaf and sheath spot Rhizoctonia solani= Rhizoctonia microsclerotia), Black bundle disease Acremonium strictum, Black kernel rot Lasiodiplodia theobromae = Botryodiplodia theobromae, Brown spot (black spot, stalk rot) Physoderma maydis, Cephalosporium kernel rot Acremonium strictum=Cephalosporium acremonium, Charcoal rot Macrophomina phaseolina, Corticium ear rot Thanatephorus cucumeris= Corticium sasaki, Curvularia leaf spot Curvularia clavata,C. eragrostidis, Curvularia inaequalis, C. intermedia, Curvularia lunata, Curvularia pallescens , Curvularia senegalensis, C. tuberculata, Didymella leaf spot Didymella exitalis, Diplodia ear rot and stalk rot Diplodia frumenti,Diplodia ear rot, stalk rot, seed rot and seedling blight Diplodia maydis, Diplodia leaf spot or leaf streak Stenocarpella macrospora=Diplodia macrospora, Downy mildews:Brown stripe downy mildew Sclerophthora rayssiae, Crazy top downy mildew Sclerophthora macrospora= Sclerospora macrospora, Green ear downy mildew (graminicola downy mildew) Sclerospora graminicola, Java downy mildew Peronosclerospora maydis = Sclerospora maydis, Sorghum downy mildew Peronosclerospora sorghi= Sclerospora sorghi, Spontaneum downy mildew Peronosclerospora spontanea=Sclerospora spontanea, Sugarcane downy mildew Peronosclerospora sacchari= Sclerospora sacchari, Dry ear rot (cob, kernel and stalk rot) Nigrospora oryzae, Ear rots, minor Alternaria alternata= A. tenuis, Aspergillus glaucus, A. niger, Aspergillus spp., Botrytis cinerea, Doratomyces stemonitis=Cephalotrichum stemonitis, Fusarium culmorum,Gonatobotrys simplex , Pithomyces maydicus, Rhizopus microspores, R. stolonifer= R.nigricans, Scopulariopsis brumptii, Ergot Claviceps gigantean, Eyespot Aureobasidium zeae= Kabatiella zeae, Fusarium ear and stalk rot Fusarium subglutinans = F. moniliforme, Fusarium kernel, root and stalk rot, seed rot and seedling blight Fusarium moniliforme, Fusarium stalk rot, seedling root rot Fusarium avenaceum, Gibberella ear and stalk rot Gibberella zeae, Gray ear rot Botryosphaeria zeae= Physalospora zeae, Gray leaf spot (Cercospora leaf spot) Cercospora sorghi= C. sorghi, C. zeae-maydis, Helminthosporium root rot Exserohilum pedicellatum=Helminthosporium pedicellatum, Hormodendrum ear rot (Cladosporium rot) Cladosporium cladosporioides = Hormodendrum cladosporioides, C. herbarum, Hyalothyridium leaf spot Hyalothyridium maydis Late wilt Cephalosporium maydis, Leaf spots, minor Alternaria alternate, Ascochyta maydis, A. tritici, A. zeicola, Bipolaris victoriae= Helminthosporium victoriae,Epicoccum nigrum, Exserohilum prolatum= Drechslera prolata, Graphium penicillioides, Leptosphaeria maydis, Leptothyrium zeae, Ophiosphaerella herpotricha, Paraphaeosphaeria michotii, Phoma sp., Septoria zeae, S. zeicola, S. zeina, Northern corn leaf blight (white blast, crown stalk rot, stripe) Setosphaeria turcica, Helminthosporium turcicum, Northern corn leaf spot, Helminthosporium ear rot Cochliobolus carbonum (anamorph: Bipolaris zeicola), Penicillium ear rot (blue eye, blue mold) Penicillium spp., P. chrysogenum, P. expansum, P. oxalicum, Phaeocytostroma stalk rot and root rot Phaeocytostroma ambiguum= Phaeocytosporella zeae, Phaeosphaeria leaf spot Phaeosphaeria maydis =Sphaerulina maydis, Physalospora ear rot (Botryosphaeria ear rot) Botryosphaeria festucae= Physalospora zeicola, Pyrenochaeta stalk rot and root rot Phoma terrestris= Pyrenochaeta terrestris, Pythium root rot Pythium spp., P. arrhenomanes, P. graminicola, Pythium stalk rot, Red kernel disease (ear mold, leaf and seed rot) Epicoccum nigrum, Rhizoctonia ear rot (sclerotial rot), Rhizoctonia zeae, Rhizoctonia root rot and stalk rot Rhizoctonia solani, Root rots, minor Alternaria alternate, Cercospora sorghi, Dictochaeta fertilis, Fusarium acuminatum F. equiseti, F. oxysporum , F. pallidoroseum, F. poae, F. roseum, G. cyanogena, F. sulphureum, Microdochium bolleyi, Mucor sp., Periconia circinata, Phytophthora cactorum, P. drechslerai, P. nicotianae, Rhizopus arrhizus , Rostratum leaf spot (Helminthosporium leaf disease, ear and stalk rot) Setosphaeria rostrata= Helminthosporium rostratum Drechs, Rust, common corn Puccinia sorghi, Rust, southern corn, Puccinia polysora, Rust, tropical corn Physopella pallescens, Sclerotium ear rot* (southern blight) Sclerotium rolfsii, Seed rot-seedling blight Bipolaris sorokiniana, B. zeicola=Helminthosporium carbonum , Diplodia maydis , Exserohilum pedicillatum, Fusarium avenaceum , F. culmorum, F. moniliforme, F. graminearum, Macrophomina phaseolina, Penicillium spp., Phomopsis sp., Pythium spp., Rhizoctonia solani, R. zeae, Sclerotium rolfsii, Spicaria sp., Selenophoma leaf spot Selenophoma sp., Sheath rot Gaeumannomyces graminis, Shuck rot Myrothecium gramineum, Silage mold Monascus purpureus, Smut, common Ustilago zeae= U. maydis, Smut, false Ustilaginoidea virens, Smut, head Sphacelotheca reiliana= Sporisorium holci-sorghi, Southern corn leaf blight and stalk rot Cochliobolus heterostrophus (anamorph: Bipolaris maydis), Southern leaf spot Stenocarpella macrospora = Diplodia macrospora Earle, Stalk rots, minor Cercospora sorghi, Fusarium episphaeria, F. merismoides, F. oxysporum, F. poae, F. roseum , F. solani , F. tricinctum, White ear rot, root and stalk rot Stenocarpella maydis= Diplodia zeae, Yellow leaf blight Ascochyta ischaemi , Phyllosticta maydis, teleomorph: Mycosphaerella zeae-maydis, Zonate leaf spot Gloeocercospora sorghi.
Diseases of Pearl Millet:
Bipolaris leaf spot Bipolaris setariae, Cercospora leaf spot Cercospora penniseti,Curvularia leaf spot Curvularia penniseti, Downy mildew Sclerospora graminicola, Plasmopara penniseti, Drechslera leaf spot Drechslera dematioidea, Ergot Claviceps fusiformis, Head mold Various fungi Myrothecium leaf spot Myrothecium roridum, Phyllosticta leaf blight Phyllosticta penicillariae, Pyricularia leaf spot Pyricularia grisea, Rhizoctonia blight Rhizoctonia solani, Rhizoctonia zeae, Rust Puccinia substriata, Seedling blight, Smut Moesziomyces penicillariae, Southern blight Sclerotium rolfsii, Top rot Fusarium moniliforme, Zonate leaf spot Gleocercospora sorghi.
Diseases of Sorghum:
Acremonium wilt Acremonium strictum Cephalosporium acremonium, Anthracnose (foliar, head, root and stalk rot) Colletotrichum graminicola (teleomorph: Glomerella graminicola), Charcoal rot Macrophomina phaseolina, Crazy top downy mildew Sclerophthora macrospora, Sclerospora macrospora., Damping-off and seed root Aspergillusspp., Exserohilium sp., Fusarium spp., Penicillium spp., Pythium spp., Rhizoctonia spp., and other species, Ergot Sphacelia sorghi, (teleomorph: Claviceps sorghi), Fusarium head blight, root and stalk rot Fusarium moniliforme (teleomorph: Gibberella fujikuroi), Fusarium spp. Grain storage mold Aspergillus spp., Penicillium spp. and other species, Gray leaf spot Cercospora sorghi, Latter leaf spot Cercospora fusimaculans, Leaf blight Setosphaeria turcica, Milo disease (Periconia root rot) Periconia circinata, Oval leaf spot Ramulispora sorghicola, Twisted top Gibberella fujikuroe var subglutinans, (anamorph: Fusarium moniliforme var. subglutinans), Pythium root rot Pythium spp., P. graminicola, Rough leaf spot Ascochyta sorghi, Rust Puccinia purpurea, Seedling blight and seed rot Colletotrichum graminicola, Exserohilum turcicum, Fusarium moniforme, Pythium spp., Smut, covered kernel Sporisorium sorghi=Sphacelotheca sorghi, Smut, head Sphacelotheca reiliana, Smut, loose kernel Sporisorium cruentum, Sooty stripe Ramulispora sorghi, Sorghum downy mildew Peronosclerospora sorghi= Sclerospora sorghi, Zonate leaf spot and sheath blight Gloeocercospora sorghi.
Diseases of Soybeans:
Alternaria leaf spot Alternaria spp. Anthracnose Colletotrichum truncatum, Black root rot Thielaviopsis basicola, Brown spot Septoria glycines, Brown stem rot Cephalosporium gregat, Charcoal rot Macrophomina phaseolina, Choanephora leaf blight Choanephora infundibulifera, Damping-off Rhizoctonia solani, Pythium aphanidermatum,P. ultimum, Downy mildew Peronospora manshurica, Drechslera blight Drechslera glycines, Frogeye leaf spot Cercospora sojina, Fusarium root rot Fusarium spp., Phomopsis seed decay Phomopsis spp., Phytophthora root and stem rot Phytophthora sojae, Pod and stem blight Diaporthe phaseolorum, Powdery mildew Microsphaera diffusa, Pythium rot, Rhizoctonia aerial blight Rhizoctonia solani, Rhioctonia root and stem rot Rhizoctonia solani, Rust Phakopsora pachyrhizi, Sclerotinia stem rot Sclerotinia sclerotiorum, Southern blight (damping-off and stem rot) = Sclerotium blight Sclerotium rolfsii, Stemphylium leaf blight Stemphylium botryosum, Sudden death syndrome Fusarium solani.
Diseases of Peanut : Alternaria leaf blight Alternaria tenuissima, Alternaria leaf spot Alternaria arachidis,Alternaria alternate, Anthracnose Colletotrichum arachidis,Aspergillus crown rot Aspergillus niger, Botrytis blight Botrytis cinerea, Charcoal rot and Macrophomina leaf spot Macrophomina phaseolina,Choanephora leaf spot Choanephora spp. Collar rot Diplodia gossypina, Colletotrichum leaf spot Colletotrichum gloeosporioides, Cylindrocladium black rot & leaf spot Cylindrocladium crotalariae, Damping-off, Aspergillus flavus, A. niger, Fusarium spp., Pythium spp., Rhizoctonia spp., Rhizopus spp., Drechslera leaf spot Bipolaris spicifera Drechslera spicifera, Fusarium peg and root rot Fusarium spp., Fusarium wilt Fusarium oxysporum, Leaf spot, early Cercospora arachidicola (teleomorph: Mycosphaerella arachidis), Leaf spot, late Paeoisariopsis personata Cercosporidium personatum, Myrothecium leaf blight Myrothecium roridum, Peanut Smut Thecaphora frezii, Phoma leaf blight Phoma microspora, Phomopsis foliar blight Phomopsis phaseoli, Phomopsis leaf spot, Pod rot (pod breakdown) Fusarium equiseti, F. solani, Pythium myriotylum, Rhizoctonia solani, Powdery mildew Oidium arachidis, Pythium peg and root rot, Pythium myriotylum,P. aphanidermatum, P. debaryanum, P. irregulare, P. ultimum, Pythium wilt Pythium myriotylum, Rhizoctonia foliar blight, peg and root rot Rhizoctonia solani, Rust Puccinia arachidis, Sclerotinia blight Sclerotinia minor, S. sclerotiorum, Stem rot (southern blight) Sclerotium rolfsii, Verticillium wilt Verticillium albo-atrum, V. dahliae, Web blotch (net blotch) Phoma arachidicola Ascochyta adzamethica, Yellow mold Aspergillus flavus, A. parasiticus
Diseases of Sunflower
Alternaria leaf blight, stem spot and head rot Alternaria alternate, A. tenuis, A. helianthi, Botrytis head rot (gray mold) Botrytis cinerea, Charcoal rot Macrophomina phaseolina= Sclerotium bataticola=Rhizoctonia bataticola, Downy mildew Plasmopara halstedii, Fusarium stalk rot Fusarium equiseti, F.solani, Fusarium tabacinum, Fusarium wilt Fusarium moniliforme, F.oxysporum, Myrothecium leaf and stem spot Myrothecium roridum,Phoma black stem Phoma macdonaldii, Phomopsis brown stem canker Phomopsis spp., P. helianthi, Phymatotrichum root rot (cotton root rot) Phymatotrichopsis omnivora=Phymatotrichum omnivorum, Phytophthora stem rot Phytophthora spp., Powdery mildew Erysiphe cichoracearum (anamorph: Oidium asteris-punicei), Leveillula compositarum, L. taurica (anamorph: Oidiopsis sicula), Sphaerotheca fuliginea, Pythium seedling blight and root rot Pythium spp., Rhizoctonia seedling blight Rhizoctonia solani, Rhizopus head rot Rhizopus arrhizus, R. nodosus, R. microspores, R. stolonifer, R. nigricans, Rust Puccinia helianthi, Uromyces junci, Sclerotinia basal stalk rot and wilt, mid-stalk rot, head rot Sclerotinia sclerotiorum, Sclerotinia minor, Sclerotium rolfsii, Septoria leaf spot Septoria helianthi , Verticillium wilt Verticillium albo-atrum, White rust, Albugo tragopogonis, Yellow rust Coleosporium helianthi (Schwein.)
Diseases of Mustard, Canola & Rape seed
Alternaria black spot Alternaria brassicae, A. brassicicola, A. raphani, Anthracnose Colletotrichum gloeosporioides (teleomorph: Glomerella cingulata), Black leg (leaf, root and stem rot) Leptosphaeria maculans (anamorph: Phoma lingam), Black root Aphanomyces raphani, Cercospora leaf spot Cercospora brassicicola, Clubroot Plasmodiophora brassicae, Damping-off Fusarium spp., Rhizoctonia solani, Downy mildew Peronospora parasitica, Head rot Rhizoctonia solani, Leaf spot Myrothecium roridum Phyllosticta brassicae, Powdery mildew Erysiphe polygoni, Sclerotinia stem rot Sclerotinia sclerotiorum White rust Albugo candida, White leaf spot Pseudocercosporella capsellae, Black mold rot Rhizopus stolonifer, Black root Aphanomyces raphani, Cercospora leaf spot Cercospora brassicicola, Clubroot Plasmodiophora brassicae, Downy mildew Peronospora parasitica, Fusarium wilt Fusarium oxysporum, Gray mold Botrytis cinerea, Head rot Rhizoctonia solani, Light leaf spot Pyrenopeziza brassicae, Pod rot Alternaria alternate, Cladosporium sp., Ring spot Mycosphaerella brassicicola, Root rot Alternaria alternate, Fusarium spp., Macrophomina phaseolina, Phymatotrichopsis omnivore, Phytophthora megasperma, Pythium debaryanum, Rhizoctonia solani, Sclerotium rolfsii, Sclerotinia stem rot Sclerotinia sclerotiorum, Seed rot, damping-off Alternaria spp., Fusarium spp., Gliocladium roseum, Nectria ochroleuca, Pythium spp., Rhizoctonia solani, Rhizopus stolonifer, Verticillium wilt Verticillium longisporum, White leaf spot = grey stem Pseudocercosporella capsellae = Cercosporella brassicae, White rust = staghead Albugo candida.
Diseases of Cotton
Anthracnose Glomerella gossypii, Colletotrichum gossypii, Areolate mildew Ramularia gossypii = Cercosporella gossypii, Ascochyta blight Ascochyta gossypii, Black root rot Thielaviopsis basicola, Boll rot Ascochyta gossypii , Colletotrichum gossypii , Southworth Glomerella gossypii, Fusarium spp., Phytophthora spp., Rhizoctonia solani, Charcoal rot Macrophomina phaseolina, Fusarium wilt Fusarium oxysporum, Leaf spot Alternaria macrospora, A. alternate, Cercospora gossypina, Mycosphaerella gossypina, Cochliobolus spicifer, Bipolaris spicifera = Curvularia spicifera, Myrothecium roridum, Rhizoctonia solani, Stemphylium solani, Lint contamination Aspergillus flavus, Nematospora spp., Nigrospora oryzae, Phymatotrichum root rot = cotton root rot Phymatotrichopsis omnivore = Phymatotrichum omnivorum, Powdery mildew Leveillula taurica, Oidiopsis sicula = Oidiopsis gossypii, Rust Cotton rust Puccinia schedonnardi, Sclerotium stem and root rot = southern blight Sclerotium rolfsii, Seedling disease complex Colletotrichum gossypii, Fusarium spp., Pythium spp., Rhizoctonia solani, Thielaviopsis basicola, Stem canker Phoma exigua, Verticillium wilt Verticillium dahliae.
Diseases of Bean (Phaseolus vulgaris L.)
Alternaria leaf and pod spot Alternaria alternate, Alternaria brassicae, Alternaria brassicicola, Angular leaf spot Phaeoisariopsis griseola, Anthracnose Colletotrichum lindemuthianum, Aphanomyces root and hypocotyl rot Aphanomyces euteiches, Ashy stem blight (charcoal rot) Macrophomina phaseolina, Black node disease (Ascochyta leaf spot) Phoma exigua= Ascochyta phaseolorum, Black root rot Thielaviopsis basicola, Cercospora leaf spot and blotch Pseudocercospora cruenta, Mycosphaerella cruenta, Cercospora canescens, Cercospora phaseoli, Cercospora caracallae, Chaetoseptoria leaf spot Chaetoseptoria wellmanii, Damping-off and stem rot, Rhizoctonia Rhizoctonia solani, Damping-off, Pythium spp., Diaporthe pod blight Diaporthe phaseolorum , Downy mildew Phytophthora nicotianae, Entyloma leaf smut Entyloma petunia, Floury leaf spot Mycovellosiella phaseoli, Fusarium root rot Fusarium solani, Gray leaf spot Cercospora vanderysti, Gray mold Botrytis cinerea, Botryotinia fuckeliana, Pink pod rot Trichothecium roseum, Powdery mildew Erysiphe polygoni, Rust Uromyces appendiculatus, Scab Elsinoe phaseoli, Soybean rust Phakopsora pachyrhizi {Asian Soybean Rust}.
Diseases of Chickpea
Acrophialophora wilt Acrophialophora fusispora, Alternaria blight Alternaria alternate, Alternaria tenuissima, Aphanomyces root rot Aphanomyces euteiches, Ascochyta blight Ascochyta rabiei, Black root rot Fusarium solani, Black streak root rot Thielaviopsis basicola, Botrytis gray mold Botrytis cinerea , Collar rot Sclerotium rolfsii, Colletotrichum blight Colletotrichum capsici, Colletotrichum dematium, Cylindrocladium root rot Cylindrocladium clavatum, Downy mildew Peronospora sp., Dry root rot Macrophomina phaseolina, Fusarium root rot Fusarium acuminatum, Fusarium arthrosporioides, Fusarium avenaceum, Fusarium equiseti, Fusarium solani, Fusarium wilt Fusarium oxysporum, Neocosmospora root rot Neocosmospora vasinfecta, Phoma blight Phoma medicaginis, Phytophthora root rot Phytophthora citrophthora, Phytophthora cryptogea,Phytophthora drechslera, Phytophthora megasperma, Pleospora leaf spot Pleospora herbarum, Powdery mildewLeveillula taurica, Erysiphe sp., Rust Uromyces ciceris-arietini, Uromyces striatus, Sclerotinia stem rot Sclerotinia sclerotiorum, Sclerotinia trifoliorum, Scopulariopsis leaf spot Scopulariopsis brevicaulis, Seedling or seed rot Aspergillus flavus, Trichothecium roseum, Stemphylium blight Stemphylium sarciniforme, Verticillium wilt Verticillium albo-atrum, Verticillium dahliae, Wet root rot Rhizoctonia solani.
Diseases of Lentil & Peas:

Alternaria blight Alternaria alternate, Anthracnose Colletotrichum lindemuthianum, Colletotrichum truncatum, Aphanomyces root rot Aphanomyces euteiches, Ascochyta blight Ascochyta fabae, Black root rot Fusarium solani, Black streak root rot Thielaviopsis basicola, Botrytis gray mold Botrytis cinerea, Cercospora leaf spot Cercospora cruenta, Cercospora lensii, Cercospora zonata, Collar rot Sclerotium rolfsii, Cylindrosporium leaf spot and stem canker Cylindrosporium sp., Downy mildew Peronospora lentis, Peronospora viciae, Dry root rot Macrophomina phaseolina= Rhizoctonia bataticola, Fusarium wilt Fusarium oxysporum, Helminthosporium leaf spot Helminthosporium sp., Leaf rot Choanephora sp., Leaf yellowing Cladosporium herbarum, Phoma leaf spot Phoma medicaginis, Powdery mildew Erysiphe pisi= Erysiphe polygoni, Leveillula taurica= Leveillula leguminosarum, Pythium root and seedling rot Pythium aphanidermatum, Pythium ultimum, Rust Uromyces craccae, Uromyces viciae-fabae, Sclerotinia stem rot Sclerotinia sclerotiorum, Stemphylium blight Stemphylium botryosum, Stemphylium sarciniforme.
Diseases of Pigeonpea
Alternaria blight Alternaria alternate, Alternaria tenuissima, Anthracnose Colletotrichum cajani, Colletotrichum truncatum, Armillaria root rot Armillaria mellea, Botryodiplodia blight Lasiodiplodia theobromae= Botryodiplodia theobromae, Botrytis gray mold Botrytis cinerea, Cercoseptoria leaf spot Cercoseptoria cajanicola, Cercospora leaf spot Mycovellosiella cajani= Cercospora cajani, Cercospora indica, Cercospora instabilis, Cercospora thirumalacharii, Cladosporium leaf blight Cladosporium oxysporum, Collar rot Sclerotium rolfsii= Corticium rolfsii, Colletotrichum stem canker Colletotrichum crassipes, Damping-off Pythium aphanidermatum, Dieback and stem canker Colletotrichum capsici, Diplodia stem canker Diplodia cajani, Dry root rot Macrophomina phaseolina, Fusarium leaf blight Fusarium pallidoroseum, Fusarium seedling rot Fusarium avenaceum, Fusarium equiseti, Fusarium wilt Fusarium udum, Halo blight Pseudomonas syringae, Macrophomina stem canker Macrophomina phaseolina, Myrothecium leaf spot Myrothecium gramineum, Periconia leaf spot Periconia byssoides, Phaeoisariopsis leaf spot Phaeoisariopsis griseola, Phoma stem canker Phoma cajani, Phyllosticta leaf spot Phyllosticta cajani, Phytophthora root rot and stem blight Phytophthora drechslera, Powdery mildew Leveillula taurica, Rust Uredo cajani, Sclerotinia stem rot Sclerotinia sclerotiorum, Seedling or seed rot Aspergillus flavus, Aspergillus niger, Wet root rot Rhizoctonia solani.
Diseases of Sugarcane
Black rot Ceratocystis adipose, Black stripe Cercospora atrofiliformis, Brown spot Cercospora longipes, Downy mildew Peronosclerospora sacchari, Fusarium sett and stem rot Gibberella fujikuroi, Leaf blast Didymosphaeria taiwanensis, Leaf blight Leptosphaeria taiwanensis,Red leaf spot (purple spot) Dimeriella sacchari, Red rot Glomerella tucumanensis, Red rot of leaf sheath and sprout rot Athelia rolfsii, Rhizoctonia sheath and shoot rot Rhizoctonia solani, Rust, common Puccinia melanocephala, Seedling blight Alternaria alternate, Bipolaris sacchari, Cochliobolus hawaiiensis, Curvularia lunata, Setosphaeria rostrata, Drechslera halodes, Sheath rot Cytospora sacchari, Smut Ustilago scitaminea, Wilt Fusarium sacchari, Zonate leaf spot Gloeocercospora sorghi.
Diseases of Carrot
Alternaria leaf blight Alternaria dauci, Black root rot Thielaviopsis basicola , Black rot (black carrot root dieback) Alternaria radicina=Stemphylium radicinum , Brown rot (Phoma disease) Leptosphaeria libanotis, Phoma rostrupii, Cavity spot Pythium spp., Pythium violae, Rhizoctonia spp., Cercospora leaf spot Cercospora carotae, Cottony rot Sclerotinia minor, Crown rot Rhizoctonia spp., Downy mildew Plasmopara crustosa, Leaf spot Ramularia spp., Powdery mildew Erysiphe heraclei, E. polygoni, E. umbelliferaum.
Diseases of Cucurbits:
Alternaria leaf blight Alternaria cucumerina, Alternaria leaf spot Alternaria alternata f. sp. Cucurbitae, Anthracnose (stem, leaf and fruit) Colletotrichum orbiculare, Belly rot Rhizoctonia solani, Black root rot Thielaviopsis basicola, Blue mold rot Penicillium spp., P. digitatum, Cephalosporium root and hypocotyl root, stem streak and dieback Acremonium spp. Cephalosporium spp., Cercospora leaf spot Cercospora citrullina, Charcoal rot (vine decline and fruit rot) Macrophomina phaseolina, Choanephora fruit rot Choanephora cucurbitarum, Crown and foot rot Fusarium solani, Damping-off Acremonium spp., Fusarium spp., F. equiseti, Phytophthora sp., Pythium spp., Rhizoctonia solani, Downy mildew Pseudoperonospora cubensis, Fusarium fruit rot Fusarium equiseti,Fusarium wilt Fusarium oxysporum, Gray mold Botrytis cinerea, Gummy stem blight (vine decline) Didymella bryoniae= Mycosphaerella melonis, Powdery mildew Sphaerotheca fuliginea, Erysiphe cichoracearum, Pythium fruit rot (cottony leak) Pythium spp., Rhizopus soft rot (fruit) Rhizopus stolonifer, Scab/gummosis Cladosporium cucumerinum, Sclerotinia stem rot Sclerotinia sclerotiorum, Septoria leaf blight Septoria cucurbitacearum, Sudden wilt Pythium aphanidermatum, Ulocladium leaf spot Ulocladium consortiale, Verticillium wilt Verticillium albo-atrum, V. dahliae, Web blight Rhizoctonia solani.
Diseases of Onion and Garlic:
Black mold Aspergillus niger, Blue mold Penicillium aurantiogriseum, = Penicillium cyclopium, Penicillium citrinum, Penicillium digitatum, Penicillium expansum, Penicillium hirsutum, Penicillium funiculosum, Penicillium oxalicum, Botrytis brown stain Botrytis cinerea, Botryotinia fuckeliana, Botrytis leaf blight Botrytis squamosa, Botrytis rot of garlic Botrytis porri , Botryotinia porri, Cercospora leaf spot Cercospora duddiae, Charcoal rot Macrophomina phaseolina =Sclerotium bataticola, Diplodia stain Lasiodiplodia theobromae Diplodia natalensis Botryodiplodia theobromae, Downy mildew Peronospora destructor, Flower and capsule blight Botrytis aclada, Botrytis allii, Botrytis squamosa, Botryotinia squamosa, Botrytis cinerea, Botryotinia fuckeliana, Fusarium basal rot Fusarium oxysporum,Fusarium bulb rot of onion and garlic Fusarium proliferatum, Fusarium damping-off Fusarium oxysporum, Fusarium verticillioides Fusarium moniliforme, Fusarium subglutinans, Fusarium proliferatum= Cephalosporium proliferatum, Fusarium solani, Fusarium equiseti, Fusarium tricinctum, Leaf blotch Cladosporium allii-cepae, Mycosphaerella allii-cepae, Mushy rot Rhizopus microspores, Rhizopus stolonifer, Mycelial neck rot Botrytis byssoidea, Botryotinia allii, Neck rot Botrytis aclada, Botrytis allii, Penicillium decay of garlic Penicillium hirsutum, Pink root Phoma terrestris, Powdery mildew Leveillula taurica, Oidiopsis sicula Scalia, Purple blotch Alternaria porri, Pythium seed rot and damping-off Pythium irregulare, Pythium coloratum, Pythium graminicola, Pythium mamillatum, Pythium paroecandrum, Pythium rostratum, Pythium spinosum, Pythium sylvaticum , Pythium torulosum, Pythium ultimum, Pythium vexans, Rhizoctonia seed rot and seedling disease Rhizoctonia solani, Rust Puccinia allii, Scape blight Botrytis aclada, Botrytis allii, Botrytis porri, Botrytis squamosa, Sclerotinia rot Sclerotinia sclerotiorum, Smudge Colletotrichum circinans, Smut Urocystis colchici, Stemphylium leaf blight and stalk rot Stemphylium vesicarium, White rot Sclerotium cepivorum.
Diseases of Pepper (Capsicum spp.):
Anthracnose Colletotrichum gloeosporioides, C. capsici, Glomerella cingulata, Cercospora (frogeye) leaf spot Cercospora capsici, Charcoal rot Macrophomina phaseolina, Choanephora blight (wet rot) Choanephora cucurbitarum, Damping-off and root rot Rhizoctonia solani, Phytophthora spp., Fusarium spp., Pythium spp., Downy mildew Peronospora tabacina, Fusarium stem rot Fusarium solani, Fusarium wilt Fusarium oxysporum f. sp. Capsici,Gray leaf spot Stemphylium solani, Gray mold Botrytis cinerea, Phytophthora blight Phytophthora capsici, Powdery mildew Oidiopsis sicula, Leveillula taurica, Southern blight Sclerotium rolfsii, Verticillium wilt erticillium dahliae, White mold Sclerotinia sclerotiorum
Diseases of Potato (Solanum tuberosum L.):
Brown spot and Black pit Alternaria alternate, Cercospora leaf blotch Mycovellosiella concors= Cercospora concors, Cercospora solani, Early blight Alternaria solani, Gray mold Botrytis cinerea, Late blight Phytophthora infestans, Phoma leaf spot Phoma andigena, Powdery mildew Erysiphe cichoracearum, Powdery scab Spongospora subterranean, Rhizoctonia canker and black scurf Rhizoctonia solani, Septoria leaf spot Septoria lycopersici, Silver scurf Helminthosporium solani, Verticillium wilt Verticillium albo-atrum.
Diseases of Tomato (Solanum lycopersicum L.):
Alternaria stem canker Alternaria alternate f. sp. Lycopersici, , Anthracnose Colletotrichum coccodes, Black mold Alternaria alternate, Buckeye rot Phytophthora capsici, Charcoal rot Macrophomina phaseolina, Didymella stem rot Didymella lycopersici, Early blight Alternaria tomatophila, Fusarium foot rot Fusarium solani, Gray leaf spot Stemphylium botryosum f. sp. Lycopersici,Gray mold Botrytis cinerea, Gray mold rot (Botrytis fruit rot) Botrytis cinerea, Late blight Phytophthora infestans,Phoma rot Phoma destructiva var. destructive, Phytophthora root rot Phytophthora capsici,Powdery mildew Leveillula taurica, Pythium damping-off and stem rot Pythium aphanidermatum, P. debaryanum, P. ultimum, Rhizoctonia damping-off, root rot, stem rot, sem canker, foliar blight, fruit rot Rhizoctonia solani, Septoria leaf spot Septoria lycopersici, Verticillium wilt Verticillium albo-atrum, V. dahliae, White mold Sclerotinia minor, S. sclerotiorum.
Diseases of Apple:
Alternaria blotch Alternaria mali, Alternaria rot Alternaria alternate, American brown rot Monilinia fructicola, Anthracnose canker and bull's-eye rot Cryptosporiopsis curvispora, Apple scab Venturia inaequalis, Apple ring rot and canker Botryosphaeria berengeriana, Armillaria root rot shoestring root rot Armillaria mellea, Bitter rot Glomerella cingulata, Black pox Helminthosporium papulosum, Black root rot Xylaria mali, Black rot, frogeye leafspot and canker Botryosphaeria obtuse, Blister canker = nailhead canker Biscogniauxia marginata, Blue mold Penicillium spp., Brooks fruit spot Mycosphaerella pomi, Brown rot blossom blight and spur infection Monilinia laxa, (Aderhold & Ruhland) Honey, Clitocybe root rot Armillaria tabescens Clitocybe tabescens, Diaporthe canker Diaporthe tanakae, Phomopsis tanakae, Diplodia canker Botryosphaeria stevensii, Diplodia mutila, Fruit blotch, leaf spot and twig canker Phyllosticta solitaria, Glomerella leaf spot Glomerella cingulata, Colletotrichum gloeosporioides, Gray mold rot dry eye rot, blossom-end rot Botrytis cinerea, Leptosphaeria canker and fruit rot Diapleella coniothyrium Leptosphaeria coniothyrium, Leucostoma canker and dieback Leucostoma cincta, Cytospora cincta, Marssonina blotch Diplocarpon mali, Marssonina coronaria, Moldy core and core rot Alternaria spp., Cladosporium spp., Coniothyrium sp., Epicoccum spp., Pleospora herbarum, Stemphylium spp., Ulocladium spp., Monilia leaf blight Monilinia mali, Monochaetia twig canker Seiridium unicorne Monochaetia mali, Perennial canker Neofabrae perennans, Cryptosporiopsis perennans, Phomopsis canker, fruit decay and rough bark Phomopsis mali, Phymatotrichum root rot cotton root rot Phymatotrichopsis omnivore, Phytophthora crown, collar and root rot sprinkler rot Phytophthora spp., Pink mold rot Trichothecium roseum Cephalothecium roseum, Powdery mildew Podosphaera leucotricha.
Diseases of Banana:
Anthracnose Colletotrichum musae, Armillaria corn rot Armillaria mellea,Black leaf streak (black Sigatoka) Mycosphaerella fijiensis, Black root rot Rosellinia bunodes, Brown spot Cercospora hayi, Ceratocystis fruit rot Ceratocystis paradoxa, Cigar-end Verticillium theobromae, Crown rot Fusarium pallidoroseum, Colletotrichum musae, Verticillium theobromae, Fusarium spp., Cylindrocladium root rot Cylindrocladium spp., Eyespot Dreschslera gigantean, Fruit rot Botryosphaeria ribis, Fungal root-rot Fusarium solani, Fusarium wilt (Panama disease) Fusarium oxysporum, Leaf spot Curvularia eragrostidis, Drechslera musae-sapientum, Leptosphaeria musarum, Pestalotiopsis disseminate, Ceratocystis paradoxa, Sigatoka (yellow Sigatoka) Mycosphaerella musicola.
Diseases of Citrus (Citrus spp.):
Alternaria brown spot Alternaria alternate, Anthracnose wither-tip Glomerella cingulata, Colletotrichum gloeosporioides, Black mold rot Aspergillus niger, Botrytis blossom and twig blight, gummosis Botrytis cinerea, Brown rot (fruit) Phytophthora citricola, P. citrophthora, Diplodia gummosis and stem-end rot Lasiodiplodia theobromae Botryodiplodia theobromae, Leaf spot Mycosphaerella horii, Phytophthora foot rot, gummosis and root rot Phytophthora citrophthora.
Diseases of Grape (Vitis spp.):
Alternaria rot Alternaria alternate, Anthracnose and bird's-eye rot Elsinoe ampelina (anamorph: Sphaceloma ampelinum), Berry rots and raisin molds Ascochyta sp., Aspergillus aculeatus, Aspergillus spp., Cladosporium spp., Fusarium spp., Helminthosporium spp., Monilia sp., Stemphylium botryosum, Botrytis bunch rot and blight (Gray mold) Botrytis cinerea (teleomorph: Botryotinia fuckeliana) Cercospora leaf spot (cercosporiose) Phaeoramularia dissiliens Cercospora sp., Diplodia cane dieback and bunch rot (Cane-tip blight) Lasiodiplodia theobromae Diplodia natalensis, Downy mildew Plasmopara viticola, Powdery mildew Uncinula necator, Wood rot (decay) Cephalosporium spp., Phellinus igniarius, Stereum hirsutum.
Diseases of Mango (Mangifera indica L.):
Alternaria leaf spots Alternaria alternate, Anthracnose Colletotrichum gloeosporioides, Black mold rot Aspergillus niger, Black rot Ceratocystis paradoxa, Blossom blight Botrytis cinerea, Branch canker Botryosphaeria ribis, Fusicoccum sp., Ceratocystis wilt Ceratocystis fimbriata, Dieback Botryosphaeria disrupta, Fruit rot Alternaria alternate, Phytophthora nicotianae, Leaf blight Bipolaris hawaiiensis, Leaf spot Curvularia lunata, Leptosphaeria sp., Macrophoma sp., Phaeosphaerella mangiferae, Phoma sorghina, Pseudocercospora mali, Septoria sp., Verticillium lecanii. Mango malformation Fusarium subglutinans, Powdery mildew Erysiphe cichoracearum, Stem canker Phoma sp., Stem end rot Botryosphaeria rhodina, Twig blight Diaporthe spp.,
Diseases of Papaya:
Alternaria fruit spot Alternaria alternate, Angular leaf spot Leveillula taurica, Anthracnose Colletotrichum gloeosporioides, Black spot Asperisporium caricae, Cercospora papaya, Brown spot Corynespora cassiicola, Collar rot Cylindrocladium crotalariae, Damping off/ Root rot Colletotrichum gloeosporioides, Phytophthora palmivora, Pythium aphanidermatum,Pythium debaryanum, Rhizoctonia solani, Dry rot Phoma caricae-papayae, Fruit rot Monilia sp., Fruit spot Cercospora mamaonis, Fusarium fruit rot Fusarium solani, Greasy spot Corynespora cassiicola, Leaf spot Alternaria sp., Cercospora mamaonis, Choanephora cucurbitarum, Curvularia carica-papayae, Powdery mildew Erysiphe cichoracearum, Oidium caricae, Rhizopus soft rot Rhizopus stolonifer.
The agrochemical composition of the present invention in addition to Pymetrozine along with a Triazole, wherein Triazole may be selected from Propiconazole, Tebuconazole, Hexaconazole, Flusilazole or Tricyclazole further comprises inactive excipients including but not limited to dispersant, anti-freezing agent, anti-foam agent, wetting agent, suspension aid, anti-microbial agent, thickener, quick coating agent or sticking agents (also referred to as “stickers” or “binders”) and buffering agent.

A dispersant is a substance which adsorbs onto the surface of particles and helps to preserve the state of dispersion of the particles and prevents them from re-aggregating. Dispersants are added to agrochemical compositions to facilitate dispersion and suspension during manufacture, and to ensure the particles re-disperse into water in a spray tank. They are widely used in wettable powders, suspension concentrates and water-dispersible granules. Surfactants that are used as dispersants have the ability to adsorb strongly onto a particle surface and provide a charged or steric barrier to re-aggregation of particles. The most commonly used surfactants are anionic, non-ionic, or mixtures of the two types. For wettable powder compositions, the most common dispersants are sodium lignosulphonates. For suspension concentrates, very good adsorption and stabilization are obtained using polyelectrolytes, such as sodium naphthalene sulphonate formaldehyde condensates. Tristyrylphenolethoxylate phosphate esters are also used. Nonionics such as alkylarylethylene oxide condensates and EO-PO block copolymers are sometimes combined with anionics as dispersants for suspension concentrates. In recent years, new types of very high molecular weight polymeric surfactants have been developed as dispersants. These have very long hydrophobic ‘backbones’ and a large number of ethylene oxide chains forming the ‘teeth’ of a ‘comb’ surfactant. These high molecular weight polymers can give very good long-term stability to suspension concentrates because the hydrophobic backbones have many anchoring points onto the particle surfaces. Examples of dispersants used herein include but not limited to sodium lignosulphonates; sodium naphthalene sulphonate formaldehyde condensates; tristyrylphenolethoxylate phosphate esters; aliphatic alcohol ethoxylates; alky ethoxylates; EO-PO block copolymers; and graft copolymers or mixtures thereof.

Anti-freezing agent as used herein can be selected from the group consisting of polyethylene glycols, methoxypolyethylene glycols, polypropylene glycols, polybutylene glycols, glycerin and ethylene glycol.

Water-based compositions often cause foam during mixing operations in production. In order to reduce the tendency to foam, anti-foam agents are often added either during the production stage or before filling into bottles. Generally, there are two types of anti-foam agents, namely silicones and non-silicones. Silicones are usually aqueous emulsions of dimethyl polysiloxane while the non-silicone anti-foam agents are water-insoluble oils, such as octanol and nonanol, or silica. In both cases, the function of the anti-foam agent is to displace the surfactant from the air-water interface.

A wetting agent is a substance that when added to a liquid increases the spreading or penetration power of the liquid by reducing the interfacial tension between the liquid and the surface on which it is spreading. Wetting agents are used for two main functions in agrochemical compositions: during processing and manufacture to increase the rate of wetting of powders in water to make concentrates for soluble liquids or suspension concentrates; and during mixing of a product with water in a spray tank or other vessel to reduce the wetting time of wettable powders and to improve the penetration of water into water-dispersible granules. Examples of wetting agents used in wettable powder, suspension concentrate, and water-dispersible granule compositions include but not limited to sodium lauryl sulphate; sodium dioctylsulphosuccinate; alkyl phenol ethoxylates; and aliphatic alcohol ethoxylates or mixtures thereof.

Suspension aid in the present description denotes a natural or synthetic, organic or inorganic material with which the active substance is combined in order to facilitate its application to the plant, to the seeds or to the soil. This carrier is hence generally inert, and it must be agriculturally acceptable, in particular to the plant being treated. The carrier may be solid (clays, natural or synthetic silicates, silica, resins, waxes, solid fertilizers, and the like or mixtures thereof) or liquid (water, alcohols, ketones, petroleum fractions, aromatic or paraffinic hydrocarbons, chlorinated hydrocarbons, liquefied gases, and the like or mixtures thereof).

Biocides / Microorganisms cause spoilage of formulated products. Therefore anti-microbial agents are used to eliminate or reduce their effect. Examples of such agents include, but are not limited to: propionic acid and its sodium salt; sorbic acid and its sodium or potassium salts; benzoic acid and its sodium salt; p-hydroxy benzoic acid sodium salt; methyl p-hydroxy benzoate; and biocide such as sodium benzoate, 1,2-benzisothiazoline-3-one, 2-methyl-4-isothiazolin-3-one, 5-chloro-2-methyl-4-isothiazolin-3-one, potassium sorbate, parahydroxy benzoates or mixtures thereof.

Thickeners or gelling agents are used mainly in the composition of suspension concentrates, emulsions and suspoemulsions to modify the rheology or flow properties of the liquid and to prevent separation and settling of the dispersed particles or droplets. Thickening, gelling, and anti-settling agents generally fall into two categories, namely water-insoluble particulates and water-soluble polymers. It is possible to produce suspension concentrate compositions using clays and silicas. Examples of these types of materials, include, but are limited to, montmorillonite, e.g. bentonite; magnesium aluminum silicate; and attapulgite. Water-soluble polysaccharides have been used as thickening-gelling agents for many years. The types of polysaccharides most commonly used are natural extracts of seeds and seaweeds are synthetic derivatives of cellulose or mixtures thereof. Examples of these types of materials include, but are not limited to, guar gum; locust bean gum; carrageenam; xanthan gum; alginates; methyl cellulose; sodium carboxymethyl cellulose (SCMC); hydroxyethyl cellulose (HEC) or mixtures thereof. Other types of anti-settling agents are based on modified starches, polyacrylates, polyvinyl alcohol and polyethylene oxide or mixtures.

The quick coating agent can be a conventionally available sticker, for example polyesters, polyamides, poly- carbonates, polyurea and polyurethanes, acrylate polymers and copolymers, styrene copolymers, butadiene copolymers, polysaccharides such as starch and cellulose derivatives, vinylalcohol, vinylacetate and vinylpyrrolidone polymers and copolymers, polyethers, epoxy, phenolic and melamine resins, polyolefins and define copolymersand mixtures thereof. Examples of preferred polymers are acrylate polymers such as poly(methacrylate), poly(ethyl methacrylate), poly(methylmethacrylate), acrylate copoylmers and styrene-acrylic copolymers as defined herein below, poly(styrene-co maleic anhydride), cellulosic polymers such as ethyl cellulose, cellulose acetate, cellulose acetatebutyrate, acetylated mono, di, and triglycerides, poly(vinylpyrrolidone), vinyl acetate polymers and copolymers, poly(alkylene glycol), styrene butadiene copolymers, poly(orthoesters), alkyd resins, and mixtures of two or more of these. Polymers that are biodegradable are also useful in the present invention. As used herein, a polymer is biodegradable if is not water soluble, but is degraded over a period of several weeks when placed in an application environment. Examples of biodegradable polymers that are useful in the present invention include biodegradable polyesters, starch, polylactic acid starch blends, polylactic acid, poly(lactic acid-glycolic acid) copolymers, polydioxanone, cellulose esters, ethyl cellulose, cellulose acetate butyrate, starch esters, starch esteraliphatic polyester blends, modified corn starch, polycaprolactone, poly(namylmethacrylate), wood rosin, polyanhydrides, polyvinylalcohol, polyhydroxy butyratevalerate, biodegradable aliphatic polyesters, and polyhydroxybutyrate or mixtures thereof.

Buffering agent as used herein is selected from group consisting of calcium hydroxyapatite, Pottasium Dihydrogen Phosphate, Sodium Hydroxide, carbonated apatite, calcium carbonate, sodium bicarbonate, tricalcium phosphate, calcium phosphates, carbonated calcium phosphates, amine monomers, lactate dehydrogenase and magnesium hydroxide.

The solvent for the composition of the present invention may include water, water-soluble alcohols and dihydroxy alcohol ethers. The water-soluble alcohol which can be used in the present invention may be lower alcohols or water-soluble macromolecular alcohols. The term "lower alcohol", as used herein, represents an alcohol having 1-4 carbon atoms, such as methanol, ethanol, n-propanol, isopropanol, n-butanol, tert-butanol, etc. Macromolecular alcohol is not limited, as long as it may be dissolved in water in a suitable amount range, e.g., polyethylene glycol, sorbitol, glucitol, etc. The examples of suitable dihydroxy alcohol ethers used in the present invention may be dihydroxy alcohol alkyl ethers or dihydroxy alcohol aryl ethers. The examples of dihydroxy alcohol alkyl ether include ethylene glycol methyl ether, diethylene glycol methyl ether, propylene glycol methyl ether, dipropylene glycol methyl ether, ethylene glycol ethyl ether, diethylene glycol ethyl ether, propylene glycol ethyl ether, dipropylene glycol ethyl ether, etc. The examples of dihydroxy alcohol aryl ethers include ethylene glycol phenyl ether, diethylene glycol phenyl ether, propylene glycol phenyl ether, dipropylene glycol phenyl ether, and the like. Any of the above mentioned solvent can be used either alone or in combination thereof.

The wettable dry granules (WDG) can be applied after disintegration and dispersion in water. Water dispersible granules can be formed by a) agglomeration, b) spray drying, or c) extrusion techniques.

WDG compositions offer a number of advantages in packaging, ease of handling and safety. The WDG are preferably of uniform size and which are free flowing, low dusting and readily disperse in water to form a homogenous solution of very small particles which may pass through conventional spray nozzles. Ideally WDG compositions when dispersed in water under gentle agitation for five minutes have residues of less than 0.01% on a 150 µm sieve screen and less than 0.5% on a 53 µm screen. The granules can usually be measured accurately by volume which is convenient for the end user.

Wettable powders can be prepared by dissolving insecticide in sufficient solvent with or without heating to give a solution and spraying the resulting solution onto a solid carrier or diluent. Alternatively insecticides which are solid and of a friable nature may be blended and ground with mineral diluents. The carriers generally used for wettable powders are sorbent inorganic materials commonly of mineral origin such as the kaolinites, montmorillonites, attapulgites, diatomaceous earths and vermiculites. Diluents generally used in toxicant formulations are such inert solids as talc, pyrophyllite, frianite, pumice and as per the knowledge of a person skilled in the art.

Oil dispersion (OD) formulation cane be prepared by below mentioned general process;
The organic solvent is charged into a vessel and the clay or silica type rheology modifier is added into the vessel with high shear mixing to allow complete wetting of the rheology modifier. The insecticide, safener, dispersants, and emulsifier may then be added to the vessel under shearing conditions until the formation of uniform oil dispersion is achieved. The polymer or oligomer capable of hydrogen bonding may be introduced into the oil dispersion at a point where the desired thickening effect is achieved.

The SC composition can be prepared by below described method;
STEP-I: Adding anti-microbial agent and gum in water under continuous stirring followed by slow addition. Continuing stirring until homogeneous dispersion is formed.
STEP-II: Mixing anti-freezing agent, dispersant, wetting agent, anti-microbial agent and anti-foaming agent in water for 30 minute until homogeneous solution is formed. Finally add Pymetrozine along with Triazole, wherein Triazole may be selected from Propiconazole, Tebuconazole, Hexaconazole, Flusilazole or Tricyclazole is added slowly under continuous stirring at 30 minute till homogeneous dispersion is obtained. Milling the slurry through bead mill until required particle size is achieved.
Step-III: Adding rest of water, anti-foaming agent and gum solution under continuous stirring to get desired viscosity of the suspension. Continue stirring for about 4 hr to obtain homogeneous composition.

Emulsifiable concentrate (EC) formulations are a blend of insecticide, organic solvent, and surfactants. When the solution is diluted into water, a spontaneous milky emulsion forms with dispersed phase droplets. When sprayed, this dilute emulsion gives a uniform and accurate application of insecticide on the crop, which is essential for effective pest control. The formulation of the insecticide into an Emulsifiable Concentrate can ensure uniform spreading and wetting under normal spray and weather conditions.
ZC is a mixed formulation of CS and SC and is a stable aqueous suspension of microcapsules and solid fine particles, each of which contains Pymetrozine along with Triazole, wherein Triazole may be selected from Propiconazole, Tebuconazole, Hexaconazole, Flusilazole or Tricyclazole. The formulation is intended for dilution into water prior to spray application. Formulating the active ingredients together eliminates the need for tank mixing, which can lead to incompatibility, and facilitates control of a wider range of pests with fewer applications. Like other aqueous liquid formulations, ZC formulations are easy to handle and measure, dust free, non-flammable and offer good miscibility with water. Pymetrozine along with Triazole, wherein one or more Triazole may be selected from Propiconazole, Tebuconazole, Hexaconazole, Flusilazole or Tricyclazole is encapsulated for various purposes, such as to increase the residual biological activity, or to reduce the acute toxicity, or to obtain a physical or chemically stable water-based formulation. The purpose determines whether the “free” active ingredient and the “release rate” are relevant properties of a specific product.
The process for preparing the present agrochemical composition can be modified accordingly by any person skilled in the art based on the knowledge of the manufacturing the composition. However all such variation and modification is still covered by the scope of present invention.

EXAMPLES

Example 1: Pymetrozine 15% + Propiconazole 10% SE (Suspo Emulsion)

Composition %
1 Pymetrozine (95%) 16.30
2 Propiconazole (95%) 11.00
3 Tristyrylphenol polyethoxyester phosphate 2.50
4 N-Octanol 10.00
6 Acrylic graft copolymer 3.00
5 Lignosulfonic acid, ethoxylated, sodium salts 2.00
6 Block copolymer on butanol 2.50
7 Silicone antifoam 0.50
8 Benzisothiazoline 0.20
9 Glycol 6.00
10 Bentonite Clay 2.00
11 Polysaccharides 0.16
12 DM water 48.99
TOTAL 100.00
Procedure:
Step 1 Gum Solution should be made 12-18 hour prior to use. Take required quantity of water, biocide, and defoamer and homogenise, then slowly add gum powder to it and stir till complete dissolution.
Step 2 Charge required quantity of DM water need to be taken in designated vessel for Flowable concentrate/ Suspension concentrate/ Flowable slurry production.
Step 3 Add required quantity of Wetting agent, dispersing agent & suspending agents, colourant/deye and homogenise the contents for 45 – 60 minutes using high shear homogeniser.
Step 4 Then add technical and other remaining adjuvants excluding ‘antifreeze & thickeners’ are added to it and homogenised to get uniform slurry ready for grinding.
Step 5 Before grinding half the quantity of antifoam was added and then material was subjected to three cycles of grinding in Dyno mill.
Step 6 Half quantity of the antifoam was added along with antifreeze after grinding process completes and before sampling for in process analysis.
Step 7 Now add the second technical dissolved in solvent and emulsifier into this formulation vessel
Step 8 Finally add gum solution to this formulation and dend to QC for quality check

Example 2: Pymetrozine 7.5% + Propiconazole 5 % ZC (Zeon Concentrate)

Composition %
1 Pymetrozine (95%) 8.40
2 Propiconazole (95%) 5.80
3 Tristyrylphenol polyethoxyester phosphate 3.00
4 Lignosulfonic acid, ethoxylated, sodium salts 0.80
5 Copolymer butanol EO/PO 2.50
6 DL-propanediol-(1,2) 5.00
7 Polydimethylsiloxane 0.20
8 1,2-benzisothiazol-3-one 0.01
9 Xanthan Gum 0.20
10 Polyurea capsule wall 2.50
11 Mixture of heavy aromatic hydrocarbons 20.00
12 Dodecyl-benzene sulfonic acid Ca-salt linear 2.00
13 Ammonia 0.20
14 Sulphuric acid 0.60
15 Water 40.89
TOTAL 100.00

Procedure:
Step 1 Solid technical premix formulation: Charge water to a stainless steel vessel. Under agitation, add the dodecylbenzenesulfonic acid sodium salt into the vessel. Under agitation, heat the vessel to 60°C. As soon as a clear solution is formed, add the molten copolymer butanol PO/EO and continue the agitation. Once the solution is clear, add 1,2-benzisothiazol-3-one and cool to room temperature.
Step 2 Charge a stainless steel reactor, equipped with a high shear disperser and a bulk-mixing agitator, with water. While mixing, add the ligno sulfonate sodium salt. Then, add the ‘Emulsifier Premix’ and agitate to ensure complete blending. Cool the mixture to room temperature
Step 3 While mixing, charge a stainless steel reactor with a mixture of heavy aromatic hydrocarbons. Then, slowly add melted Propiconazole technical to the reactor. Afterwards, charge isocyanic acid methyl-m-phenylene ester to the reactor. Continue mixing. Cool the reactor contents to room temperature.
Step 4 Using a high shear disperser, charge the ‘Organic Solution’ into the ‘Aqueous Phase Solution’ and continue to shear for 30 min. Then, heat the reactor to around 50 °C. During heating, reduce the agitation.
Step 5 After the wall polymerization reaction, increase the agitator to high speed. Add the antifoam to the mixture. Under slight vacuum, allow the mixture to de-gas for approximately 30 minutes to remove CO2 from the solution. Add ammonium hydroxide, the linear polysaccharide and propylene glycol. Then, add 1,2-benzisothiazol-3-one and mix for some minutes. Add sulfuric acid for pH adjustment. Check the formulation to specifications
Step 6 Liquid Technical Premix formulation:
Step 7 2% Gel Preparation: Charge the required quantity of water to a vessel, equipped with a high shear stirrer and start the agitation. Add the required amount of 1,2-benzisothiazol-3-one preservative. Mix until homogenous. Add the required amount of heteropolysaccharide thickener and mix vigorously until it is fully wetted.
Step 8 Charge the required quantity of water to a vessel, equipped with bulk agitator and a high shear device and start agitation. Add the required amount of propylene glycol and mix until uniform. Add the polydimethylsiloxane antifoam and ensure that it is well dispersed. Add the tristyrylphenol polyethoxyester phosphate dispersing agent and mix until uniform. Ensure that the dispersing agent is fully dispersed.
Step 9 Add the sodium ligninsulfonate dispersing agent and mix until it is fully dispersed. Continue agitating the vessel contents until both dispersing agents are dissolved. AddPymetrozine technical and mix until the active ingredient is fully dispersed. Mill this mixture through a Colloid mill and subsequently through a Dynomill to meet the specified particle size.
Step 10 Add propylene glycol, the polydimethylsiloxane antifoam, the thickener and theillbase Pymetrozine Millbase to a vessel, equipped with bulk agitator. Mix until uniform. Add the required amount of 2% aqueous pre-gel and continue agitation until the formulation is homogeneous and has the target viscosity. Mix well. Adjust the pH by adding the potassium hydroxide solution or sulfuric acid to around 5. Adjust the volume of water. Mix well.
Step 11 Charge the remaining quantity of water to a vessel, equipped with bulk agitator and start agitation. Add Pymetrozine Premix and Propiconazole Premix and mix until uniform. Add the required amount of 2% pre-gel and continue agitation until the formulation is homogeneous and a target viscosity of around 600 mPa.s is reached. Mix well. Adjust the pH by adding potassium hydroxide solution or sulfuric acid until a target pH of around 5-7 is reached. Mix well.
Step 12 Final product is sent for QC approval.
Step 13 After approval material is packed in requied pack sizes.

Example 3: Pymetrozine 15% + Tebuconazole 12.5% SC (Suspension Concentrate)
Composition %
1 Pymetrozine (95%) 16.30
2 Tebuconazole (95%) 13.70
3 Acrylic graft copolymer 3.00
4 Lignosulfonic acid, ethoxylated, sodium salts 2.00
5 Block copolymer on butanol 2.50
6 Silicone antifoam 0.50
7 Benzisothiazoline 0.20
8 Glycol 6.00
9 Bentonite Clay 2.00
10 Polysaccharides 0.16
11 DM water 53.64
TOTAL 100.00

Procedure:
Step 1 Gum Solution should be made 12-18 hour prior to use. Take required quantity of water, biocide, and defoamer and homogenise, then slowly add gum powder to it and stir till complete dissolution.
Step 2 Charge required quantity of DM water need to be taken in designated vessel for Flowable concentrate/ Suspension concentrate/ Flowable slurry production.
Step 3 Add required quantity of Wetting agent, dispersing agent & suspending agents, colourant/deye and homogenise the contents for 45 – 60 minutes using high shear homogeniser.
Step 4 Then add technical and other remaining adjuvants excluding ‘antifreeze & thickeners’ are added to it and homogenised to get uniform slurry ready for grinding.
Step 5 Before grinding half the quantity of antifoam was added and then material was subjected to three cycles of grinding in Dyno mill.
Step 6 Half quantity of the antifoam was added along with antifreeze after grinding process completes and before sampling for in process analysis.
Step 7 Finally add gum solution to this formulation and dend to QC for quality check

Example 4: Pymetrozine 30% + Tebuconazole 25% WG (Water Dispersible Granules)
Composition %
1 Pymetrozine (95%) 32.10
2 Tebuconazole (95%) 26.85
3 Sodium salt of Phenol sulphonic acid condensate 3.00
4 Polyacrylate co-polymer 7.00
6 Sodium alkylnaphthalenesulfonate, formaldehyde condensate 2.50
5 Silicone based antifoam 0.50
6 Polyvinyl pyrollidone 0.50
7 Starch 20.00
8 China clay 7.55
TOTAL 100.00

Procedure:
Step 1 Charge the required quantity of filler, wetting agent, dispersing agent, and suspending agent, & technical in premixing blender for homogenization for 30 minutes.
Step 2 Pre-blended material is than grinded through Jet mill/ air classifier mills. Finely grinded material is blended in post blender till it becomes homogeneous. (for approx 1.5 hr)
Step 3 Homogeneous material is analysed. After getting approval from QC dept. material is unloaded into 25 kg. HDPE bag with LDPE liner inside.
Step 4 Finely grinded powder is mixer with required quantity of water to form extrudable dough.
Step 5 Dough is passed through extruder to get granules of required size.
Step 6 Wet granuleas are passed through Fluidised bed drier and further graded using vibrating screens.
Step 7 Final product is sent for QC approval.
Step 8 After approval material is packed in requied pack sizes.

Example 5: Pymetrozine 30% + Tebuconazole 25% WP (Wettable Powder)
Composition %
1 Pymetrozine (95%) 32.10
2 Tebuconazole (95%) 26.85
3 Sodium alkyl naphthalene sulfonate blend 5.00
4 Sodium alkylnaphthalenesulfonate, formaldehyde condensate 7.00
6 Silicone based antifoam 0.50
5 Pppt Silica 20.00
8 China clay 8.55
TOTAL 100.00

Procedure:
Step 1 Charge the required quantity of filler, wetting agent, dispersing agent, and suspending agent, & technical in premixing blender for homogenization for 30 minutes.
Step 2 Pre-blended material is than grinded through Jet mill/ air classifier mills. Finely grinded material is blended in post blender till it becomes homogeneous. (for approx 1.5 hr)
Step 3 Homogeneous material is analysed. After getting approval from QC dept. material is unloaded into 25 kg. HDPE bag with LDPE liner inside.

Example 6: Pymetrozine 15% + Hexaconazole 5% SC (Suspension Concentrate)
Composition %
1 Pymetrozine (95%) 16.30
2 Hexaconazole (94%) 5.85
3 Acrylic graft copolymer 3.00
4 Lignosulfonic acid, ethoxylated, sodium salts 2.00
6 Block copolymer on butanol 2.50
5 Silicone antifoam 0.50
6 Benzisothiazoline 0.20
7 Glycol 6.00
8 Bentonite Clay 2.00
9 Polysaccharides 0.16
10 DM water 61.49
TOTAL 100.00

Procedure: Similar to the one as mentioned in Example 3.

Example 7: Pymetrozine 15% + Hexaconazole 5% SE (Suspo Emulsion)
Composition %
1 Pymetrozine (95%) 16.30
2 Hexaconazole (94%) 5.85
3 Tristyrylphenol polyethoxyester phosphate 2.50
4 N-Octanol 10.00
6 Acrylic graft copolymer 3.00
5 Lignosulfonic acid, ethoxylated, sodium salts 2.00
6 Block copolymer on butanol 2.50
7 Silicone antifoam 0.50
8 Benzisothiazoline 0.20
9 Glycol 6.00
10 Bentonite Clay 2.00
11 Polysaccharides 0.16
12 DM water 48.99
TOTAL 100.00

Procedure: Similar to the one as mentioned in Example 1.

Example 8: Pymetrozine 30% + Hexaconazole 10% WG (Water Dispersible Granules)
Composition %
1 Pymetrozine (95%) 32.10
2 Hexaconazole (94%) 11.20
3 Sodium salt of Phenol sulphonic acid condensate 3.00
4 Polyacrylate co-polymer 7.00
6 Sodium alkylnaphthalenesulfonate, formaldehyde condensate 2.50
5 Silicone based antifoam 0.50
6 Polyvinyl pyrollidone 0.50
7 Starch 20.00
8 China clay 23.20
TOTAL 100.00

Procedure: Similar to the one as mentioned in Example 4.

Example 9: Pymetrozine 30% + Hexaconazole 10% WP (Wettable Powder)

Composition %
1 Pymetrozine (95%) 32.10
2 Hexaconazole (94%) 11.20
3 Sodium alkyl naphthalene sulfonate blend 5.00
4 Sodium alkylnaphthalenesulfonate, formaldehyde condensate 7.00
6 Silicone based antifoam 0.50
5 Pppt Silica 20.00
6 China clay 24.20
TOTAL 100.00

Procedure: Similar to the one as mentioned in Example 5.

Example 10: Pymetrozine 15% + Flusilazole 15% SC (Suspension Concentrate)

Composition %
1 Pymetrozine (95%) 16.30
2 Flusilazole (95%) 16.30
3 Acrylic graft copolymer 3.00
4 Lignosulfonic acid, ethoxylated, sodium salts 2.00
6 Block copolymer on butanol 2.50
5 Silicone antifoam 0.50
6 Benzisothiazoline 0.20
7 Glycol 6.00
8 Bentonite Clay 2.00
9 Polysaccharides 0.16
10 DM water 51.04
TOTAL 100.00

Procedure: Similar to the one as mentioned in Example 3.

Example 11: Pymetrozine 15% + Flusilazole 15% SE (Suspo Emulsion)

Composition %
1 Pymetrozine (95%) 16.30
2 Flusilazole (95%) 16.30
3 Tristyrylphenol polyethoxyester phosphate 2.50
4 N-Octanol 10.00
6 Acrylic graft copolymer 3.00
5 Lignosulfonic acid, ethoxylated, sodium salts 2.00
6 Block copolymer on butanol 2.50
7 Silicone antifoam 0.50
8 Benzisothiazoline 0.20
9 Glycol 6.00
10 Bentonite Clay 2.00
11 Polysaccharides 0.16
12 DM water 38.54
TOTAL 100.00
Procedure: Similar to the one as mentioned in Example 1.

Example 12: Pymetrozine 5% + Flusilazole 5% ZC (Zeon Concentrate)
Composition %
1 Pymetrozine (95%) 5.80
2 Flusilazole (95%) 5.80
3 Tristyrylphenol polyethoxyester phosphate 3.00
4 Lignosulfonic acid, ethoxylated, sodium salts 0.80
6 Copolymer butanol EO/PO 2.50
5 DL-propanediol-(1,2) 5.00
6 Polydimethylsiloxane 0.20
7 1,2-benzisothiazol-3-one 0.01
8 Xanthan Gum 0.20
9 Polyurea capsule wall 2.50
10 Mixture of heavy aromatic hydrocarbons 20.00
11 Dodecyl-benzene sulfonic acid Ca-salt linear 2.00
12 Ammonia 0.20
13 Sulphuric acid 0.60
14 Water 40.89
TOTAL 100.00
Procedure: Similar to the one as mentioned in Example 2.

Example 13: Pymetrozine 7.5% + Flusilazole 7.5 % WG (Water Dispersible Granules)

Composition %
1 Pymetrozine (95%) 8.40
2 Flusilazole (95%) 8.40
3 Block copolymer on butanol 3.00
4 Sodium salt of Phenol sulphonic acid condensate 3.00
6 Polyacrylate co-polymer 7.00
5 Sodium alkylnaphthalenesulfonate, formaldehyde condensate 2.50
6 Silicone based antifoam 0.50
7 Polyvinyl pyrollidone 0.50
8 Urea formaldehyde resin 25.00
9 China clay 18.00
TOTAL 100.00

Procedure: Similar to the one as mentioned in Example 4.

Example 14: Pymetrozine 7.5% + Flusilazole 7.5% WP (Wettable Granules)

Composition %
1 Pymetrozine (95%) 8.40
2 Flusilazole (95%) 8.40
3 Sodium alkyl naphthalene sulfonate blend 5.00
4 Sodium alkylnaphthalenesulfonate, formaldehyde condensate 7.00
6 Silicone based antifoam 0.50
5 Urea formaldehyde resin 25.00
6 China clay 22.00
TOTAL 100.00
Procedure: Similar to the one as mentioned in Example 4.

Example 15: Pymetrozine 10% + Tricyclazole 20% SC (Suspension Concentrate)
Composition %
1 Pymetrozine (95%) 11.00
2 Tricyclazole (95%) 11.60
3 Acrylic graft copolymer 3.00
4 Lignosulfonic acid, ethoxylated, sodium salts 2.00
6 Block copolymer on butanol 2.50
5 Silicone antifoam 0.50
6 Benzisothiazoline 0.20
7 Glycol 6.00
8 Bentonite Clay 2.00
9 Polysaccharides 0.16
10 DM water 61.04
TOTAL 100.00
Procedure: Similar to the one as mentioned in Example 3.

Example 16: Pymetrozine 10% + Tricyclazole 20% SE (Suspo Emulsion)

Composition %
1 Pymetrozine (95%) 11.00
2 Tricyclazole (95%) 11.60
3 Tristyrylphenol polyethoxyester phosphate 2.50
4 N-Octanol 10.00
6 Acrylic graft copolymer 3.00
5 Lignosulfonic acid, ethoxylated, sodium salts 2.00
6 Block copolymer on butanol 2.50
7 Silicone antifoam 0.50
8 Benzisothiazoline 0.20
9 Glycol 6.00
10 Bentonite Clay 2.00
11 Polysaccharides 0.16
12 DM water 48.54
TOTAL 100.00
Procedure: Similar to the one as mentioned in Example 1.

Example 17: Pymetrozine 20% + Tricyclazole 40% WG (Water Dispersible Granules)
Composition %
1 Pymetrozine (95%) 21.60
2 Tricyclazole (95%) 42.60
3 Sodium salt of Phenol sulphonic acid condensate 3.00
4 Polyacrylate co-polymer 7.00
6 Sodium alkylnaphthalenesulfonate, formaldehyde condensate 2.50
5 Silicone based antifoam 0.50
6 Polyvinyl pyrollidone 0.50
7 Starch 15.00
8 China clay 7.30
TOTAL 100.00
Procedure: Similar to the one as mentioned in Example 4.

Example 18: Pymetrozine 20% + Tricyclazole 40% WP (Wettable Granules)
Composition %
1 Pymetrozine (95%) 21.60
2 Tricyclazole (95%) 42.60
3 Sodium alkyl naphthalene sulfonate blend 5.00
4 Sodium alkylnaphthalenesulfonate, formaldehyde condensate 7.00
6 Silicone based antifoam 0.50
5 Pppt Silica 20.00
6 China clay 3.30
TOTAL 100.00
Procedure: Similar to the one as mentioned in Example 4.

EXAMPLE 19: STORAGE STABILITY DATA
Comparison of the stability of formulations
The stability of each of the fromulation of Example 1 to Example 18 were tested for 1 month to 24 months stability at room temperature and at elevated temperature study under the following conditions: Heat stability study at 54 + 2 0C for 14 days and Cold storage stability at 0 + 2 0C for 14 days. The required parameters studied are active content, pH, Persistent Foaming, Suspensibility, Pourability and Viscosity was studied Respective amounts were measured using different instruments and parametes. The results are shown in the Table below of Examples 1 to 18. The results were found satisfactory and this formulation is passing in all physicochemical properties.
Storage stability study of formulation of Example 1 to Example 18
Specification Initial Heat stability study at 54 + 2 0C for 14 days Cold storage stability at 0 + 2 0C for 14 days
Parameters In House
Description Off-white to Beige liquid Complies Complies Complies
Pymetrozine Content 14.25-15.75 Complies Complies Complies
Pymetrozine Suspensibility Mini 80% Complies Complies Complies
Propiconazole Content 9.5-10.5 Complies Complies Complies
Propiconazole Suspensibility Mini 80% Complies Complies Complies
pH 5.0-9.0 Complies Complies Complies
Particle size D50 <3, D90 <10 Complies Complies Complies
Pourability 95 % min Complies Complies Complies
Specific gravity 1.05 – 1.15 Complies Complies Complies
Viscosity 350 -900 cps Complies Complies Complies

Room temperature storage data of the formulation of Example 1 to Example 18
Specification Study Duration
Parameters In House 1 month 6 month 12 months 24 months
Description Off-white to Beige liquid Complies Complies Complies Complies
Pymetrozine Content 14.25-15.75 Complies Complies Complies Complies
Pymetrozine Suspensibility Mini 80% Complies Complies Complies Complies
Propiconazole Content 9.5-10.5 Complies Complies Complies Complies
Propiconazole Suspensibility Mini 80% Complies Complies Complies Complies
pH 5.0-9.0 Complies Complies Complies Complies
Particle size D50 <3, D90 <10 Complies Complies Complies Complies
Pourability 95 % min Complies Complies Complies Complies
Specific gravity 1.05 – 1.15 Complies Complies Complies Complies
Viscosity 350 -900 cps Complies Complies Complies Complies

EXAMPLE 20: FIELD EFFICACY TRIALS
A synergistic effect exists wherever the action of a combination (ready-mix) of active ingredient is greater than the sum of the action of each of the components alone. Therefore a synergistically effective amount or an effective amount of a synergistic composition or combination is an amount that exhibits greater fungicidal activity than the sum of the fungicidal activities of the individual components.
In the field of agriculture, it is often understood that the term “synergy” is as defined by Colby S.R. in an article entitled “ Calculation of the synergistic and antagonistic responses of herbicide combinations” published in the journal Weeds, 1967, 15, p.20-22, incorporated herein by reference in its entirety. The action expected for a given combination of two active components can be calculated as follows:
XY
E = X + Y - -----------
100

in which E represents the expected percentage of Insecticidal or fungicidal control for the combination of the two insecticide or fungicides at defined dose (for example equal to x and y respectively), X is the percentage of insecticidal or fungicidal control observed by active ingredient I at defined dose (equal to x) and Y is the percentage of insecticidal or fungicidal control observed by Active Ingredient II (equal to Y). When the percentage of insecticidal or fungicidal control observed for the combination is greater than the expected percentage, there is a synergistic effect.
Trial 1
To study the synergistic effect of Pymetrozine with Propiconazole, Tebuconazole, Hexaconazole, Flusilazole and Tricyclazole, an experiment was conducted in micro plot (5m x 4m). The paddy seedling were transplanted and raised as per the normal agronomic practices. The brown plant hopper culture were released artificially allow to multiply and establish on paddy seedlings. The spraying was done manually with knapsack sprayer with 400 liter water per hectare. The assessment was done by counting the number of insect at before and 5 days after spraying. The percent insect control calculated as below:
% Insect control = 100 – 100 x (Number of insect observed in treated / Number of Insect in Untreated check. The synergistic effect was calculated by Colby’s formula.
Table 1: Brown Plant Hopper (Nilaparvata lugen) control in Paddy (Oryza sativa)
No. Treatments Formulation per Hectare (g or ml) Active Ingredient/ Hectare Brown Plant Hopper Control (%) After 5 day
Observed Value Calculated Value Synergistic effect
1 Pymetrozine 15% + Propiconazole 10% SE 1000 150 + 100 96 84.4 1.14
2 Pymetrozine 15% + Tebuconazole 12.5% SC 1000 150 + 125 95 83.2 1.14
3 Pymetrozine 15% + Hexaconazole 5% SC 1000 150 + 50 97 84 1.15
4 Pymetrozine 15% + Flusilazole 15% SC 1000 150 + 150 95 84.2 1.13
5 Pymetrozine 10% + Tricyclazole 20% SC 1500 150 + 300 97 83 1.17
6 Pymetrozine 50% WG + Propiconazole 25% EC (tank mix) 300 + 400 150 + 100 61 84.4 0.72
7 Pymetrozine 50% WG + Tebuconazole 25% EC (tank mix) 300 + 500 150 + 125 62 83.2 0.75
8 Pymetrozine 50% WG + Hexaconazole 5% SC (tank mix) 300 + 1000 150 + 50 53 84 0.63
9 Pymetrozine 50% WG + Flusilazole 40% EC (tank mix) 300 + 375 150 + 150 55 84.2 0.65
10 Pymetrozine 50% WG + Tricyclazole 75% WP (tank mix) 300 + 400 150 + 300 54 83 0.65
11 Pymetrozine 50% WG 300 150 + 400 80 _ _
12 Propiconazole 25% EC 400 100 22 _ _
13 Tebuconazole 25% EC 500 125 16 _ _
14 Hexaconazole 5% SC 1000 50 20 _ _
15 Flusilazole 40% EC 375 150 21 _ _
16 Tricyclazole 75% WP 400 300 15 _ _
17 Untreated Check _ _ _ _ _
Note: SE Suspo Emulsion, SC Suspension Concentrate, WG Water Dispersible Granules, EC- Emulsifiable Concentrate, WP Wettable Powder
The results of experiment shows that all ready mix novel composition of Pymetrozine with Propiconazole, Tebuconazole, Hexaconazole, Flusilazole, Tricyclazole shows high synergistic activity against Brown plan hopper as compared to their tank mixes as well as their individual application.
Trial 2: Disease control in Paddy (Oryza sativa L.)
This experiment was conducted in micro plot where paddy seedling was transplanted in 4 x 4 m plot size. All the agronomic practices like irrigation, fertilizer application, weeding was done as per the standard agronomic practices. These micro plots had paddy crop in previous season and heavily infested with sheath blight disease. As soon as paddy reaches to active tillering stage artificial inoculation were done with laboratory culture of Rhizoctonia solani. Two foliar applications of inventive fungicidal mixtures were done at 10 days interval starting from 3rd day of artificial inoculation. The observations on sheath blight disease severity were recorded at 10 days after last foliar application and percent disease index calculated by below formula. The percent disease control was calculated by disease severity in untreated plot.
Assessment for Sheath Blight:
Observed 100 tillers per plot and rated visually as per the ratings below.
Score Description
0 No infection
1 Vertical spread of the disease up to 20% of plant height
3 Vertical spread of the disease up to 21-30% of plant height
5 Vertical spread of the disease up to 31- 45% of plant height
7 Vertical spread of the disease up to 46 - 65% of plant height
9 Vertical spread of the disease more than 66% of plant height
Sum of numerical rating x 100
Percent Disease Index = ----------------------------------------------------------------
Total number of tiller observed x Maximum rating

% Disease Control = 100–(100 - Disease Index in treatment/Disease index in Untreated plot)
Table 2: Sheath blight (Rhizoctonia solani) control in Paddy (Oryza sativa)
No. Treatments Formulation per Hectare (g or ml) Active Ingredient/ Hectare Sheath blight Control (%) caused by Rhizoctonia solani
Observed Value Calculated Value Synergistic effec
1 Pymetrozine 7.5% + Propiconazole 5% ZC 2000 150 + 100 93 75.7 1.23
2 Pymetrozine 30% + Tebuconazole 25%WG 500 150 + 125 94 78.13 1.20
3 Pymetrozine 30% + Hexaconazole 10%WG 500 150 + 50 90 74.08 1.21
4 Pymetrozine 7.5% + Flusilazole 7.5% WG 2000 150 + 150 91 75.7 1.20
5 Pymetrozine 20% + Tricyclazole 40% WG 750 150 + 300 90 70.03 1.29
6 Pymetrozine 50% WG + Propiconazole 25% EC (tank mix) 300 + 400 150 + 100 46 75.7 0.61
7 Pymetrozine 50% WG + Tebuconazole 25% EC (tank mix) 300 + 500 150 + 125 51 78.13 0.65
8 Pymetrozine 50% WG + Hexaconazole 5% SC (tank mix) 300 + 1000 150 + 50 49 74.08 0.66
9 Pymetrozine 50% WG + Flusilazole 40% EC (tank mix) 300 + 375 150 + 150 50 75.7 0.66
10 Pymetrozine 50% WG + Tricyclazole 75% WP (tank mix) 300 + 400 150 + 300 45 70.03 0.64
11 Pymetrozine 50% WG 300 150 + 400 19 _ _
12 Propiconazole 25% EC 400 100 70 _ _
13 Tebuconazole 25% EC 500 125 73 _ _
14 Hexaconazole 5% SC 1000 50 68 _ _
15 Flusilazone 40% EC 375 150 70 _ _
16 Tricyclazole 75% WP 400 300 63 _ _
17 Untreated Check _ _ _ _
Note: ZC- Zeon Concentrate, WG- Wettable Granules, WP- Wettable Powder, EC- Emulsifiable Concentrate, SC- Suspension Concentrate
The observation on percent disease control of sheath blight indicates that high level of synergism were observed in the treatments of Pymetrozine 7.5%+ Propiconazole 5% ZC, Pymetrozine 30%+ Tebuconazole 25% WG, Pymetrozine 30% + Hexaconazole 10% WG and Pymetrozine 7.5% + Fluysilazole 7.5% WG and Pymetrozine 20% + Tricyclazole 40% WG. The sheath blight disease control as well as duration of control was also observed longer in all these novel ready mix compositions of Pymetrozine with triazoles. The synergism was observed in all the treatments of tank mixes.
,CLAIMS:We claim;

1. An agrochemical composition comprising bioactive amounts of Pymetrozine along with a Triazole wherein Triazole may be selected from Propiconazole, Tebuconazole, Hexaconazole, Flusilazole or Tricyclazole with at least one inactive excipient.
2. The agrochemical composition as claimed in claim 1 wherein the ratio of Pymetrozine along with a Triazole, wherein Triazole may be selected from Propiconazole, Tebuconazole, Hexaconazole, Flusilazole or Tricyclazole is 1:20 to 20:1.
3. The agrochemical composition as claimed in claim 1 or 2 wherein the ratio of Pymetrozine along with a Triazole, wherein Triazole may be selected from Propiconazole, Tebuconazole, Hexaconazole, Flusilazole or Tricyclazole is 1: 5 to 5: 1.
4. The agrochemical composition according to claim 1 to 3, wherein inactive excipients can be selected from the group consisting of dispersant, anti-freezing agent, anti-foam agent, wetting agent, suspension aid, anti-microbial agent, thickener, quick coating agent or sticking agents and buffering agent.
5. The agrochemical composition as claimed in claim 1 to 3, wherein the composition are selected from Suspo emulsion (SE), Suspension concentrate (SC), Zeon Concentrate (ZC), Wettable powders (WP), Water dispersible granules or wettable granules (WDG or WG).
6. The agrochemical composition as claimed in claim 1, wherein the said composition is used in Cotton (Gossypium spp.), Paddy (Oryza sativa), Wheat (Triticum aestavum), Barley (Hordeum vulgare), Maize (Zea mays), Sorghum (Sorghum bicolor), Pearl millet (Pennisetum glaucum), Sugarcane (Saccharum officinarum) , Sugarbeet (Beta vulgaris), Soybean (Glycin max), Peanut (Arachis hypogaea), Sunflower (Helianthus annuus) , Mustard (Brassica juncea), Rape seed (Brassica napus), Linseed (Linum usitatissimum), Sesame (Sesamum indicum), Green gram (Vigna radiate), Black gram (Vigna mungo), Chickpea (Cicer aritinum), Cowpea (Vigna unguiculata), Redgram (Cajanus cajan), Frenchbean (Phaseolus vulgaris), Indian bean (Lablab purpureus), Horse gram (Macrotyloma uniflorum), Field pea (Pisum sativum), Cluster bean (Cyamopsis tetragonoloba), Lentils (Lens culinaris), Brinjal (Solanum melongena), Cabbage (Brassica oleracea var. capitata), Cauliflower (Brassica oleracea var. botrytis), Okra (Abelmoschus esculentus) , Onion (Allium cepa L.), Tomato (Solanum lycopersicun) , Potato (Solanum tuberosum) , Sweet potato (Ipomoea batatas), Chilly (Capsicum annum), Garlic (Allium sativum), Cucumber (Cucumis sativus) and Melons (Cucumis melo), Radish (Raphanus sativus), Carrot (Dacus carota subsp. sativus), Turnip (Brassica rapa subsp rapa), Apple (Melus domestica), Banana (Musa spp.), Citrus groups (Citrus spp.), Grape (Vitis vinifera), Guava (Psidium guajava), Litchi (Litchi chinensis), Mango (Mangifera indica), Papaya (Carica papaya), Pineapple (Ananas comosus), Pomegranate (Punica granatum) , Sapota (Manilkara zapota), Tea (Camellia sinensis), Coffea (Coffea Arabica), Turmeric (Curcuma longa), Ginger (Zingiber officinale), Cumin (Cuminum cyminum), Fennel (Foeniculum vulgare), Coriander (Coriandrum sativum), Black Pepper (Piper nigrum), Stevia (Stevia rebaudiana), Safed musli (Chlorophytum tuberosum), Rose (Rosa spp.), Jasmine (Jasminum spp.), Marigold ( Tagetes spp.), Common daisy (Bellis perennis), Dahlia (Dahlia hortnesis), Gerbera.

7. The agrochemical composition as per claim 1, wherein the said composition is effective against paste selected from Apple Mealy bug (Phenococcus aceris), bean aphid (Aphis fabae), black citrus aphid (Toxoptera aurantii), citrus black scale (Saissetia oleae), cabbage aphid (Brevicoryne brassicae, Lipaphis erysimi), citrus red scale (Aonidiella aurantii), citrus mealybug (Planococcus citri), corn leaf aphid (Rhopalosiphum maidis), cotton aphid (Aphis gossypii), cotton leaf hoppers (Amrasca biguttula), cotton mealy bug (Planococcus spp. And Pseudococcus spp.), cotton stainer (Dysdercus suturellus), cotton whitefly (Bemisia tabaci), cowpea aphid (Aphis crassivora), grain aphid (Sitobion avenae), golden glow aphid (Uroleucon spp.), grape mealybug (Pseudococcus maritimus), green peach aphid (Myzus persicae), greenhouse whitefly (Trialeurodes vaporariorum)spp., Mango hopper (Amtritodus atkinsoni, Idioscopus spp.), papaya mealy bug (Pracoccus marginatus), pea aphid (Acyrthosiphon pisum), sugarcane mealybug (Saccharicoccus sacchari), potato aphid (Myzus persicae), potato leaf hopper (Empoasca fabae), green rice leafhopper (Nephotettix cincticeps & Nephotettix virescens, Nephotettix nigropictus), rice brown plant hopper (Nilaparvata lugen), rice white backed plant hopper, sweetpotato whitefly ( Bemisia tabaci), tarnished plant bug (Lygus lineolaris), wooly apple aphid (Eriosoma lanigerum), yellow scale (Aonidiella citrine), Frankliniella spp., Thrips palmi, Thrips tabaci and Scirtothrips dorsalis, Dysdercus spp., Leptocorisa spp and fungus selected from Acremonium, Alternaria, Ascochyta tritici, Aspergillus, Blumeria, Botryotinia, Botrytis, Botryodiplodia, Cercospora, Cephalosporium, Choanephora, Cladosporium spp., Claviceps spp., Colletotrichum spp., Curvularia, Didymella, Drechslera, Erysiphe, Fusarium, Glomerella, Helminthosporium, Leveillula, Lasiodiplodia, Macrophomina, Microdochium, Monilinia, Mycosphaerella, Oidiopsis, Puccinia, Phoma, Phytophthora, Phakopsora, Phomopsis sp., Plasmopara viticola, Pythium, Pyricularia, Pyrenophora, Physoderma maydis, Peronosclerospora, Rhizopus, Ramularia, Rhizoctonia, Sarocladium, Sclerotinia, Septoria, Stemphylium, Tilletia tritici, Typhula, Uncinula necator, Urocystis spp., Ustilago tritici, Ustilaginoidea, Venturia inaequalis, Verticillium.

8. The agrochemical composition comprising of Pymetrozine along with a Triazole wherein Triazole may be selected from Propiconazole, Tebuconazole, Hexaconazole, Flusilazole or Tricyclazole as claimed in any of the preceding claims and exemplified with working examples as disclosed.