α,ω-DICARBOXIMIDE DERIVATIVES AS USEFUL URQ-SELECTIVE Α1A ADRENOCEPTOR BLOCKERS FIELD OF THE INVENTION This invention relates to certain novel α,ω-dicarboximide derivatives which selectively inhibit binding to the ecu adrenergic receptor, a receptor which has been shown to be important in the treatment of benign prostatic hyperplasia. The compounds of the present invention are potentially useful in the treatment of benign prostatic hyperplasia. This invention also relates to methods for synthesizing the novel compounds, pharmaceutical compositions containing the compounds, methods of treating benign prostatic hyperplasia using the compounds, and intermediate compounds used in the preparation of novel compounds. BACKGROUND OF THE INVENTION Benign prostatic hyperplasia (BPH), a nonmalignant enlargement of the prostate, is the most common benign tumor in men. Approximately 50% of all men older than 65 years have some degree of BPH and a third of these men have clinical symptoms consistent with bladder outlet obstruction (Hieble and Caine, Fed. Proc., 1986; 45:2601). Worldwide benign and malignant diseases of the prostate are responsible for more surgery than diseases of any other organ in men over the age of fifty. It is generally accepted that there are two components of BPH, a static and a dynamic component. The static component is due to enlargement of the prostate gland, which may result in compression of the urethra and obstruction to the flow of urine from the bladder. The dynamic component is due to increased smooth muscle tone of the bladder neck and the prostate itself (which interferes with emptying of the bladder) and is regulated by alpha 1 adrenergic receptors (α1-ARs). The medical treatments available for BPH address these components to varying degrees, and the » therapeutic choices are expanding. Surgical treatment options address the static component of BPH and include transurethral resection of the prostate (TURP), open prostatectomy, balloon dilatation, hyperthermia, stents and laser ablation. Although, TURP is the gold standard treatment for patients with BPH, approximately 20-25% of patients do not have a satisfactory long - term outcome (Lepor and Rigaud, J. Urol., 1990; 143:533). Postoperative urinary tract infection (5-10%), some degree of urinary incontinence (2-4%), as also reoperation (15-20 %) (Wennberg et a/.JAMA, 1987; 257:933) are some of the other risk factors involved. Apart from surgical approaches, there are some drug therapies which address the static component of this condition. Finasteride (Proscar, Merck), is one such therapy which is indicated for the treatment of symptomatic BPH. This drug is a competitive inhibitor of the enzyme 5a-reductase which is responsible for the conversion of testosterone to dihydrotestosterone in the prostate gland (Gormley et al, N. Engl. J. Med., 1992; 327:1185). Dihydrotestosterone appears to be the major mitogen for prostate growth, and agents which inhibit 5-α-reductase reduce the size of the prostate and improve urine flow through the prostatic urethra. Although finasteride is a potent 5α-reductase inhibitor and causes a marked decrease in serum and tissue concentration of dihydrotestosterone, it is only moderately effective in treating symptomatic BPH (Oesterling, N.Engl.J.Med., 1995; 332:99). The effects of finasteride take 6-12 months to become evident and for many men the clinical improvement is minimal. Due to the limited effectiveness of 5α-reductase inhibitors in terms of immediate symptomatic and urodynamic relief, other pharmacological approaches have been assessed in the clinical setting. The dynamic component of BPH has been addressed by the use of adrenergic receptor blocking agents (α1-AR blockers) which act by decreasing the smooth muscle tone within the prostate gland itself, α1-adrenergic receptor antagonists appear to be much more effective and provide immediate subjective symptomatic improvements and are, therefore, the preferred modalities of treatment in the control of benign prostate hypertrophy. α1-Adrenoceptors are also present in blood vessels and play an important role in the regulation of blood pressure. Thus, α1-adrenoceptor antagonists are of particular importance as they were originally developed as antihypertensive agents and are likely also to have a beneficial affect on lipid dysfunction and insulin resistance, which are commonly associated with essential hypertension. The use of α1-AR antagonists in the treatment of BPH is related to their ability to decrease the tone of prostatic smooth muscle, leading to relief of the obstructive symptoms. Adrenergic receptors found throughout the body play a dominant role in the control of blood pressure, nasal congestion, prostate function and other processes (Harrison et al, Trends Pharmacol. Sci., 1991; 12:62). There are a number of cloned oci-AR receptor subtypes: ccu-AR, aiB-AR and am-AR (Bruno et al, Biochem. Biophys. Res. Commun., 1991; 179:1485; Forray et al, Mol. Pharmacol., 1994; 45:703; Hirasawa et al, Biochem. Biophys. Res. Commun., 1993; 195:902; Ramarao et al, J.Biol. Chem., 1992; 267:21936; Schwinn et al, JPET, 1995; 272:134; Weinberg et al, Biochem. Biophys. Res. Commun,, 1994; 201:1296). A number of laboratories have characterized the (α1-ARS in human prostate by function, radioligand binding, and molecular biological techniques (Forray et al., Mol. Pharmacol. 1994; 45:703; Hatano et al, Br.J.Pharmacol, 1994; 113:723; Marshall et al, Br. J.Pharmacol. 1992; 112:59; Marshall et al, Br. J.pharmacol., 1995; 115:781; Yamada et al .Life Sci., 1994; 54:1845). These studies provide evidence in support of the concept that the ccu-AR subtype comprises the majority of ai-ARS in human prostatic smooth muscle and mediates contraction in this tissue. These findings suggest that the development of a subtype-selective ociA-AR antagonists might result in a therapeutic ally effective agent with reduced side effects for the treatment of BPH. A variety of oci-AR blockers (terazosin, prazosin, and doxazosin) have been investigated for the treatment of symptomatic bladder outlet obstruction due to BPH, with terazosin (Hytrin, Abbott) being the most extensively studied. Although the ar AR blockers are well tolerated, approximately 10-15% of patients develop a clinically adverse event .The undesirable effects of all members of this class are similar, with postural hypotension being the most commonly experienced side effect. The α1-AR blocking agents have a more rapid onset of action. However, their therapeutic effect, as measured by improvement in the symptom score and the peak urinary flow rate, is moderate. (Oesterling, N.Engl. J.Med., 1995; 332:99). The vascular side effects (e.g., postural hypertension, dizziness, headaches, etc.) associated with these drugs is due to lack of selectivity of action between prostatic and vascular α1-adrenoceptors. Clearly, α1-adrenoceptor antagonists which have inherently greater selectivity for prostatic α1-adrenoceptors offer the potential of increased urodynamic benefits. This underscores the importance of the discovery of prostate-selective α1-adrenoceptor antagonists which will confer urodynamic improvement without the side effects associated with existing drugs. There are many description in the literature about the pharmacological activities associated with α,ω-dicarboximide derivatives. Eur. J .Med . Chem. Chemica Therapeutica; 1977; 12(2): 173, J.Indian,Chem.Soc. ,1978; LV-.819; J . Indian Chem.Soc., 1979; LVL1002 discuss the synthesis of these derivatives with CNS and antihypertensive activity . Other references like U.S. Patent Nos. 4,524,206; 4,598,078; 4,567,180; 4,479,954; 5,183,819; 4,748,240; 4,892,943; 4,797,488; 4,804,751; 4,824,999; 4,957,913; 5,420,278; 5,330,762; 4,543,355 and PCT application Nos. WO 98/37893; WO 93/21179, also describe CNS and antihypertensive activity of these compounds. There is no mention of adrenoceptor blocking activity of these compounds and thus their usefulness in the treatment of BPH did not arise. J.Med.Chem., 1983; 26:203 reports dopamine and ai-adrenergic activity of some Buspirone analogues. EP 078800 discusses α1-adrenergic receptor antagonistic activity of pyrimidinedione, pyrimidinetrione and triazinedione derivatives. These compounds, however, had low ai-adrenergic blocking activity as compared to known α1-antagonists. The earlier synthesis of various l-(4-arylpiperazm-l-yl)-3-(2-oxo-pyrrolidin-l-yl/piperidin-l-yl)alkanes and their usefulness as hypotensive and antischemic agents is disclosed in Indian Patent applications 496/DEL/95, 500/DEL/95 and 96/DEL/96. These compounds had low α1-adrenergic blocking activity (pKi ~ 6 as compared to > 8 of the known α1 -antagonists such as prazosin), and practically no adrenoceptor sub-class selectivity for ecu vs. α1B or aio adrenoceptors. Further work showed that structural modification of these compounds from lactam to dioxo compounds, i.e., from 2-oxopyrrolidin to 2,5-dioxopyrrolidin and 2,6-dioxopiperidine, enhances the adrenoceptor blocking activity, and also greatly increases the selectivity for α1A in comparison to α1B - adrenoceptor blocking activity, an essential requirement for compounds to be good candidates for treatment of benign prostatic hyperplasia(BPH) disclosed in our U.S. Patent Nos. 6,083,950 and 6,090,809 which are incorporated herein by reference. OBJECTS OF THE INVENTION Recently, it has been demonstrated that the prostate tissue of higher species like man and dog has a predominant concentration of α1A-adrenoceptor subtype. This makes it possible to develop agents with selective action against these pathological urodynamic states. The present invention is directed to the development of novel cci-adrenoceptors and which would thus offer a viable selective relief for prostate hypeitrophy as well as essential hypertension, without the side effects associated with known α1A-AR antagonists. The objective of the present invention therefore is to provide novel αω-dicarboximide derivatives that exhibit significantly greater α1A-adrenergic blocking potency than available with known compounds in order to provide specific treatment for benign prostatic hyperplasia. It is also an object of the invention to provide a process for synthesis of the novel compounds. It is a further object of the invention to provide compositions containing the novel compounds which are useful in the treatment of benign prostatic hyperplasia. SUMMARY OF THE INVENTION In order to achieve the above mentioned objectives and in accordance with the purpose of the invention as embodied and described herein, there are provided novel α,ω-dicarboximide derivatives represented by Formula I below; (FormulaRemoved) Formula -1 wherein X is selected from the group consisting of (FormulaRemoved) where the points of attachment are depicted by hashed bonds, and where one point of attachment is bonded to the carbonyl adjacent to the nitrogen and the second point of attachment is bonded to the other carbonyl; WisO.S, SOorS02; (FormulaRemoved) where m is one of the integers 2,3 or 4; RH is independently selected from H, F, Cl, Br, I, OH, straight or branched lower (C1-6) alkyl, lower (C1-6) alkoxy, lower (C1-6) perhaloalkyl, lower perhaloalkoxy; Y is selected from the group consisting of (FormulaRemoved) R, and R2 are independently selected from H, OH, CN, NO2, Cl, F, Br, I, OR3, COR3) OCOR3, COOR3, NH2, N(R4, R5), lower (C14) alkyl, lower (C1-4) alkoxy, lower (C1-4) alkylthio, lower (C1-4) perhaloalkyl, lower (C1-4) perhaloalkoxy lower (C1-4) alkoxy substituted with one or more of F, Cl, Br, I, OH, or OR3, or optionally substituted groups selected from aryl, aralalkyl, heterocyclyl or heteroaryl, said substituents being H, F, Cl, Br, I, OH, OR3, lower (C1-4) alkyl, lower (C1-4) allcyl substitued with one or more of F, Cl, Br, I, OH or OR3, wherein R3, is selected from the group consisting of H, straight or branched C1-C6 alkyl or perhaloalkyl; R4 and R5 are independently selected from the group consisting of H, CHO, substituted or unsubstituted lower (C1-4 alkyl, lower (C1-4) alkoxy, COR3 COOR3, CH2CH(OR3)2, CH2COOR3, CH2CHO or (CH2)2OR3 where R3 is the same as defined above; Re, R?, Rg, Rg and RIO are independently selected from H, OH, CN, NO2, Cl, F, Br, I, straight or branched lower (C1-4) alkyl, optionally substituted with one or more halogens, lower (CM) alkoxy optionally substituted with one or more halogens, (C3-6) cycloalkoxy, NH2, N-lower (C1-4) alkylamino, N, N-di-lower (C1-C4) alkylamino, N-lower (C1-C4) alkyl amino carbonyl, hydroxy substituted with aromatic or non-aromatic five or six membered ring, phenyl or phenyl substituted by Cl, F, Br, I, N02, NH2, (C1-4) alkyl or (C1-4) alkoxy, (C1-4) perhaloalkyl, (C1-4) perhaloalkoxy wherein the broken line (-—) is a single bond or no bond. The present invention also provides pharmaceutical compositions for the treatment of benign prostatic hyperplasia. These compositions comprise an effective amount of at least one of the above compounds of Formula I and/or an effective amount of at least one physiologically acceptable acid addition salt thereof, with a pharmaceutically acceptable carrier. An illustrative list of particular compounds of the invention is given below: l-[4-(2-Hydroxyphenyl)piperazin-l-yl]-3-(2,6-dioxopiperidin-l-yl) propane hydrochloride; (Compound No. 1) 2-[3-{4-(2-(2,2,2-Trifluoroethoxy) phenyl) piperazin-l-yl}propyl]-3a, 4,7,7a-tetrahydro-lH-isoindole-1,3 (2H)-dione hydrochloride; (Compound No. 2) l-[4-{2-(2,2,2-Trifluoroethoxy)phenylpiperazin-l-yl]-3-(2,6-dioxopiperidin-l-yl)propanehydrochloride; (Compound No. 3) 2-[3-{4-(2-Ethoxyphenyl)piperazin-l-yl, 1-N-oxide} propyl]-3a,4,7,7a-tetrahydro-lH-isoindole-1,3 (2H)-dione; (Compound No. 4) l_[4-(2-Ethoxvphenyl)piperazin-l-yl]-3-(2,6-dioxopiperadin-l-yl)ethane hydrochloride; (Compound No. 5) 2- [3 - {4-(2-Methox yphenyl)piperazin-1 -yl} -2-hydroxyprop yl] -3 a,4,7,7 a-tetrahydro-lH-isoindole-1,3 (2H)-dione hydrochloride; (Compound No. 6) 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}-2-hydroxypropyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 7) 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl, l-N-oxide}propyl]-3a,4,7,7a-tetrahydro-lH-isoindole-1,3 (2H)-dione; (Compound No. 8) 2-[3 - {4-(2-Isopropoxyphenyl)piperazin- 1-yl, 1,4-N,N-dioxide} propyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3-(2H)-dione; (Compound No. 9) 2-[3-{4-(2-Ethoxyphenyl)piperazin- 1-yl, 1,4-N,N-dioxide }propyl]-3a-4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione; (Compound No. 10) 2-[3-{4-(2-Ethoxyphenyl)piperazin-l-yl}-2-hydroxypropyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3-(2H)-dione hydrochloride; (Compound No. 11) 2-[3-{4-(2-Ethoxyphenyl)piperazin-l-yl}propyl]-5,6-dihydroxy-3a,4,5,6,7,7a-hexahydro-lH-isoindole-l,3(2H)-dione; (Compound No. 12) 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-5,6-dihydoxy-3a,4,5,6,7,7a-hexahydro-lH-isoindole-l,3 (2H)-dione; (Compound No. 13) 2-[3-{4-(2-Hydroxyphenyl)piperazin-l-yl}-2-hydroxypropyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 14) 2-[2- {4-(2-Ethoxyphenyl)piperazin-1 -yl} ethyl]-3 a,4,7,7a-tetrahydro-1H-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 15) 2-[2-{4-(2-(2,2,2-Trifluoroethoxy)phenyl)piperazin-l-yl}ethyl]-3a,4,7,7a-tetrahydro-lH-isoindole-1,3 (2H)-dione hydrochloride; (Compound No. 16) 2-[3-{4-(2-Ethoxyphenyl)piperazin-l-yl}propyl]-5-chloro-6-hydroxy-3a,4,5,6,7,7a-hexahydro-lH-isomdole-l,3(2H)-dionehydrochloride; (Compound No. 17) 2-[3-{4-(2-Ethoxyphenyl)piperazin-l-yl}propyl]-5-hydroxy-3a,4,5,6,7,7a-hexahydro-lH-isoindole-1,3 (2H)-dione hydrochloride; (Compound No. 18) 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-5,6-epoxy-3a,4,5,6,7,7a-hexahydro-lH-isoindole-l,3(2H)-dione; (Compound No. 19) 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-5-hydroxy-3a,4,5,6,717a-hexahydro-lH-isoindole-l,3(2H)-dione; (Compound No. 20) 2-[3-{4-(2-Isopropoxy-5-hydroxyphenyl)piperazin-l-yl}propyl]-3a,4,7,7a-tetrahydro-lH-isoindole-1,3 (2H)-dione hydrochloride; (Compound No. 21) 2-[3-{4-(2-Hydroxyphenyl)piperazin-l-yl, l-N-oxide}propyl]-3a,4,7,7a-tetrahydro-lH-isoindole-1,3 (2H)-dione; (Compound No. 22) 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-5,6-dihydroxy-3a,4,5,6,7,7a, hexahydro-lH-isoindole-1,3 (2H)-dione-hydrochloride; (Compound No. 23) 2-[3-{4-(2-Ethoxy-5-hydroxyphenyl)piperazin-l-yl}propyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3-(2H)-dione hydrochloride; (Compound No. 24) 2-[3-{4-(2-Isopropoxy-4-nitrophenyl)piperazin-l-yl}propyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 25) 2-[3-{4-(2-Isopropoxy-4-aminophenyl)piperazin-l-yl}propyl]-3a,4(7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 26) 2-[3- {4-(2-isopropoxy-6-hydroxyphenyl)piperazin- 1-yl }propyl]-3a-,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 27) 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-5-chloro-6-hydroxy-3a,4,5,6,7)7a-hexahydro-lH-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 28) l-[4-(2-Isopropoxyphenyl)piperazin-l-yl]-2-hydroxy-3-(2,6-dioxopiperidin-l-yl)propane hydrochloride; (Compound No. 29) 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}-2-hydroxypropyl]-5,6-epoxy-33,4,5,6,7,7a-hexahydro-lH-isoindole-l,3(2H)-dione; (Compound No. 30) 2-[3-{4-(2-(2,2,2-Trifluoroethoxyphenyl)piperazin-l-yl}-2-hydroxypropyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 31) 2-[3-{4-(2-(2,2,2-Trifluoroethoxy)phenyl)piperazin-l-yl}propyl]-5,6-epoxy-3a,4,5,6,7,7a-hexahydro-lH-isoindole-l,3(2H)-dione; (Compound No. 32) 2-[3-{4-(2-(2,2,2-Trifluoroethoxy)phenyl)piperazin-l-yl}propyl]-5-hydroxy-3a,4,5,6,7,7a-hexahydro-lH-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 33) 2-[3-{4-(2-(2,2,2-Trifluoroethoxy)phenyl)piperazin-l-yl}-2-hydroxypropyl]-5,6-epoxy-3a,4,5,7,7 a-hexahydro-IH-isoindole-1,3(2H)-dione; (Compound No. 34) 2- [3 - {4-(2-Is opropoxy-3 -hydroxyphenyl)piperazin-1 -yl} prop yl] - 3 a,4,7,7 a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 35) l-[4-(2-Isopropoxy-5-hydroxyphenyl)piperazin-l-yl]-3-(2,6-dioxopiperdin-l-yl)piperazin-l-yl]-3-(2,6-dioxopiperidin-l-yl)propane hydrochloride; (Compound No. 36) l-[4-(2-Isopropoxy-6-hydroxyphenyl)piperazin-l-yl]-3-(2,6-dioxopiperdin-l-yl)propane hydrochloride; (Compound No. 37) l-[4-(2-Isopropoxy-3-hydroxyphenyl)piperazm-l-yl]-3-(2,6-dioxopiperidin-l-yl)propane hydrochloride; (Compound No. 38) l-[4-{2-(2,2,2-Trifluoroethoxy)phenyl)piperazin-l-yl]-2-hydroxy-3-(2,6-dioxopiperidin-l-yl)propane hydrochloride; (Compound No. 39) 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-4-acetoxy-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 40) 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-4-hydroxy-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 41) 2-[N-{N' -(2-Isopropoxyphenyl)aminoethyl}aminopropyl] -3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 42) 2-[3-{4-(2-Cyclopentyloxyphenyl)piperazin-l-yl}propyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 43) l-[4-(2- hydroxyphenyl)piperazin-l-yl]- 2-hydroxy -3-(2,6-dioxopiperidin-l-yl]propane hydrochloride; (Compound No. 44) 2-[3~{4-(2-Biphenyl)piperazin -l-yl}propyl]- 3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 45) 2-[N-{N'-(2-Isopropoxyphenyl)aminoethyl}acetylaniinopropyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 46) 2-[N-{N' -(2-Isopropoxyphenyl) acetylaminoethyl}aminopropyl]-3a,4,7,7a-tetraliydro-lH-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 47) 2-[N-[{N'-(2-Isopropoxyphenyl)aminoethyl}hydroxyethyl]aminopropyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 48) 1 - [4-(2-Is opropoxyphenyl)piperazin- 1-yl] -1 -oxo-3 -(2,6-dioxopiperidin-l -yl)propane hydrochloride; (Compound No. 49) 2-[N-{N'-(2-Isopropoxyphenyl)aminoethyl}acetaldehyde-aminopropyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione; (CompoundNo. 50) 2-[ N-{N'-(2-Isopropoxyphenyl)aminoethyl} aminopropyl-N,N'-(bis hydroxyethyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione; (Compound No. 51) 2-[N-{N'-(2-Isopropoxyphenyl) aminoethyl}ethylacetate-aminopropyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione; (Compound No. 52) 2-[N-{N'-(2-Isopropoxyphenyl)aminoethyl}formylaminopropyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione; (Compound No. 53) 2-[3-{4-(2-Isopropoxyphenyl)piperazin-3-oxo-l-yl}propyl]- 3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione; (Compound No. 54) l-[4-(2- Methoxyphenyl)piperazin-l-yl-4-N-oxide]- 3-(2,6-dioxopiperidin-1-yl]propane; (Compound No. 55) l-[N-{N'-(2-Methoxyphenyl)aminoethyl}]-3-(2,6-dioxopiperidin-l-yl)aminopropane hydrochloride; (Compound No. 56) l-[N-N-{N'-(2-Methoxyphenyl)aminoethyl}]-3-(2,6-dioxopiperidin-l-yl)aminopropane hydrochloride; (Compound No. 57) 2-[3- {4-(2-Isopropoxy-4-acetylaminophenyl)piperazin-l-yl }propyl]- 3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 58) 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-7,7a-dihydro-lH-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 59) 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}-propyl]-4-hydroxy-3a,4)5,6>7,7a-hexahydro-lH-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 60) 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}-propyl]-exo-4,7-epoxy-3a,4, 7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 61) 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}-l-oxo-propyl]-3a,4, 7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 62) 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}-l-oxo-propyl]-3a,4,5,6, 7,7a-hexahydro-lH-isoindole-l,3(2H)-dione hydrochloride; (CompoundNo, 63) 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl,4-N-oxide}propyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione; (Compound No. 64) 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl,l-N-oxide}2-hydroxypropyl]-3a,4, 7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione; (Compound No. 65) 2-[3-{4-(2-Ethoxyphenyl)piperazin-l-yl }propyl]-5,6-dihydroxy-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 66) 2-[3~{3-(2-Isopropoxyphenyl)imidazolidon-l-yl }propyl]-3a,4, 7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione; (Compound No. 67) 2-[N-{N'-(2-Isopropoxyphenyl)aminoethyl} aminopropyl- N'-((3-hydroxyethyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 68) l.[4_(2-Methoxyphenyl)piperazin-l-yl-l-N-oxide]-3-(2,6-dioxopiperidin-l-yl]-2-hydroxypropane; (Compound No. 69) l-[4-(2-Hydroxyphenyl)piperazin-l-yl-l-N-oxide]- 3-(2,6-dioxopiperidin-l-yl]propane; (Compound No. 70) 2-[3-{ 4-(2-Isopropoxyphenyl)-2,3-dioxopiperazin-l-yl }-propyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione; (Compound No. 71) 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-4,7-dihydroxy-3a,4, 7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione; (Compound No. 72) 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-4,7-diacetoxy-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride; (CompoundNo. 73) 2-[N-{N'-(2-Isopropoxyphenyl) aminoethyl}ethylaminopropyl]- 3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione; (Compound No. 74) 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-5,6-dimethoxy-3a,4, 7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 75) 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-5,6-dimethoxy-3a,4,5,6> 7,7a-hexahydro-lH-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 76) 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-4,7-diphenyl-3a,4,7,7a-tetrahydro-!H-isoindole-l,3(2H)-dione hydrochloride; (Compound No. 77) 2-[3-{4-(2-Methoxyphenyl)piperazin-1 -yl}propyl]-4,7-diphenyl-3a,4, 7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride; (CompoundNo. 78) Pharmaceutically acceptable, non-toxic, acid addition salts of the compounds of the present invention having the utility of the free bases of Formula I may be formed with inorganic or organic acids, by methods well known in the art and may be used in place of the free bases. Representative examples of suitable acids for formation of such acid addition salts are maleic, fumaric, benzoic, ascorbic, pamoic, succinic, bismethylene salicylic, methanesulfonic, ethane disulfonic, acetic, propionic, tartaric, salicylic, citric, gluconic, aspartic, stearic, palmitic, itaconic, glycolic, p-aminobenzoic, glutamic, benzenesulfamic, phosphoric, hydrobromic, sulfuric, cyclohexylsulfamic, hydrochloric, and nitric acids. The present invention also includes within its scope prodrugs of the compounds of Formula I. In general, such prodrugs will be functional derivatives of these compounds which are readily converted in vivo into the defined compounds. Conventional procedures for the selection and preparation of suitable prodrugs are known. The invention also includes the enantiomers, diastereomers, N-oxides, polymorphs, pharmaceutically acceptable salts and pharmaceutically acceptable solvates of these compounds, as well as metabolites having the same type of activity. The invention further includes pharmaceutical compositions comprising the molecules of Formula I, or prodrugs, metabolites, enantiomers, diastereomers, N-oxides, polymorphs, solvates or pharmaceutically acceptable salts thereof, in combination with a pharmaceutically acceptable carrier and optionally included excipients. In yet another aspect, the invention is directed to methods for selectively blocking ecu receptors by delivering in the environment of said receptors, e.g., to the extracellular medium (or by administering to a mammal possessing said receptors), an effective amount of the compounds of the invention. DETAILED DESCRIPTION OF THE INVENTION The compounds of the present invention may be prepared by one of the reaction sequences (Schemes I-X) to yield the compounds of Formula I. The starting materials for schemes I-X may be suitably adapted to produce the more specific compounds of Formula I. SCHEME I (SchemeRemoved) Scheme I shows the synthesis of the compounds of Formula I wherein X is selected from the group consisting of (FormulaRemoved) where the points of attachment are depicted by hashed bonds, and where one point of attachment is bonded to the carbonyl adjacent to the nitrogen and the second point of attachment is bonded to the other carbonyl; WisO.S, SOorSO2; (FormulaRemoved) where m is one of the integers 2,3 or 4; RH is independently selected from H, F, Cl, Br, I, OH, straight or branched lower (C1-6) alkyl, lower (C1-6) alkoxy, lower (C1-6) perhaloalkyl, lower (C1-6) perhaloalkoxy; Y is selected from the group consisting of (FormulaRemoved) R1 and R2 are independently selected from H, OH, CN, NO2, Cl, F, Br, I, OR3 COR3, OCOR3, COOR3, NH2, N(R4, R5), lower (CM) alkyl, lower (CM) alkoxy, lower (CM) alkylthio, lower (C1-4) perhaloalkyl, lower (CM) perhaloalkoxy lower (C1-4 alkoxy substituted with one or more of F, Cl, Br, I, OH, or OR3, or optionally substituted groups selected from aryl, aralalkyl, heterocyclyl or heteroaryl, said substituents being H, F, Cl, Br, I, OH, OR3l lower (C1-4) alkyl, lower (CM) alkyl substitued with one or more of F, Cl, Br, I, OH or OR3, wherein R3, is selected from the group consisting of H, straight or branched C1-C6 alkyl or perhaloalkyl; R4 and R5 are independently selected from the group consisting of H, CHO, substituted or unsubstituted lower (CM) alkyl, lower (CM) alkoxy, COR3, COOR3, CH2CH(OR3)2, CH2COOR3, CH2CHO or (CH2)2OR3 where R3 is the same as defined above; R6, R7, R8, R9 and R10 are independently selected from H, OH, CN, NO2, Cl, F, Br, I, straight or branched lower (C1-4) alkyl, optionally substituted with one or more halogens, lower (C1-4) alkoxy optionally substituted with one or more halogens, (C3-6) cycloalkoxy, NH2, N-lower (C1-4) alkylamino, N, N-di-lower (C1-C4) alkylamino, N-lower (C1-C4) alkyl amino carbonyl, hydroxy substituted with aromatic or non-aromatic five or six membered ring, phenyl or phenyl substituted by Cl, F, Br, I, NO2, NH2 (C1-4) alkyl or (C1-4) alkoxy, (C1-4) perhaloalkyl, (C1-4) perhaloalkoxy wherein the broken line (—) is a single bond or no bond. The preparation comprises condensing α,ω-dicarboximides of Formula II with substituted phenyl of Formula El, in the presence of a base and an organic solvent at a temperature ranging from about 70-150° C for a period varying between 8-24 hours to produce the corresponding compounds of Formula I. The suitable organic solvent is a dipolar aprotic solvent selected from the group consisting of dimethylsulfoxide, N, N-dimethylformamide, hexamethylphosphorarnide and N-methyl-2-pyrrolidone. The reaction is carried out in the presence of an inorganic base preferably selected from the group potassium carbonate and sodium carbonate. The preferable temperature conditions for the reaction are 70-80°C. SCHEME II (SchemeRemoved) The compounds of the Formula I can also be prepared by Scheme EL, wherein substituted phenyl of the Formula IV is condensed with the anhydrides of Formula V, to give compounds of Formula I, wherein X, Y, A, R6, R7, R8, R9 and R10 as defined above. The reaction is carried out under reflux conditions in an organic solvent such as toluene, benzene, xylene, pyridine, acetic acid in pyridine, or mixtures thereof. The preferable temperature condition for the reaction is 70-80° C. SCHEME III (SchemeRemoved) Scheme III shows the synthesis of the compounds of Formula I (when A = -CH2-CH- CH2) which comprises the nucleophilic ring opening of the epoxide of Formula VI with the substituted phenyl of the Formula III, wherein X, Y, R6, R7, R8, R9 and R10 are as defined earlier and A is -CH2- CH(OH)- CHa-. Preferably, the reaction is carried out in organic solvent at a temperature ranging from 50-100° C for a period ranging from one to several hours. The solvent for carrying out this reaction is a dipolar aprotic solvent such as dimethylsulfoxide, N, N-dimethylformamide, sulfolane, dimethylacetamide, hexamethylphosphamide and N-methyl-2-pyrrolidine. Polar protic solvents like ethanol can also be used under reflux conditions for this reaction. The reaction can be carried out in the presence of inorganic base such as potassium carbonate or sodium carbonate, or an organic base such as triethyl arnine and diisopropylethylamine. The suitable temperature range for the reaction is 70-80°C. (FormulaRemoved) The compounds of Formula IX (Formula I, when X, Y= R7= R8=R9=R10=H) can be prepared by the reaction sequence of Scheme IV, wherein A and RG are as defined earlier. The starting material for this scheme is the compound of Formula II (when X =which is subjected to epoxidation to give a compound of Formula VII wherein A is same as defined earlier. The reaction of epoxidation is carried out in a nonpolar solvent or a polar aprotic solvent at sub-zero temperatures for a period of 24-30 hours. The product (Formula VII) formed is then condensed with substituted phenyl of Formula III (when R7 = R8 R9= R10=H) in the presence of a base and an organic solvent at a temperature ranging from 70-150°C for a period varying between 8-24 hours to produce compound of Formula VIII. Nucleophilic ring opening of epoxide of compound of Formula VIII with alcoholic hydrochloric acid gave corresponding compound of Formula X, while catalytic hydrogenation of compounds of Formula VIII in a polar solvent at reduced pressure, for a period ranging between 36-72 hours gave corresponding compounds of Formula IX. The epoxidation of compounds of Formula II is carried out with peracid such as metachloroperbenzoic acid, peracetic acid or trifluoroperacetic acid. The organic solvent used in this reaction can be selected from a group consisting of dichloromethane, dichloroethane, chloroform, tetrahydrofuran, acetone and acetonitrile. The preferred temperature conditions are 0-5° C. The condensation of the epoxide of Formula VII with compound of Formula III is carried out in a polar aprotic solvent such as dimethylsulfoxide, N,N-dimethylformamide, sulfolane, dimethylacetamide hexamethylphosphoramide and N-methyl-2-pyrrolidone. The inorganic base used in this reaction is selected from the group consisting of potassium carbonate and sodium carbonate and the preferable temperature for carrying out this reaction is 50-55° C. The nucleophilic epoxide ring opening of compounds of Formula VIII is carried out preferably with methanolic or ethanolic hydrochloric acid while the catalytic hydrogenation of the epoxide of compounds of Formula VIE is carried out in polar protic solvents such as methanol and ethanol. SCHEME V (SchemeRemoved) - The compounds of Formula XII(Formula I when X is prepared by the method of Scheme V with Y, A, R6, R7, R8, R9, and R10 groups as defined earlier. The starting material for Scheme V is the compound of Formula XI (Formula I, when X = which is subjected to oxidation to give the corresponding diol of Formula XII. The reaction is carried out preferably in a polar solvent at about 0-5° C for about one to several hours. The oxidizing agent in this reaction is selected from the group consisting of osmium tetraoxide and potassium permanganate. The reaction is carried out in a polar protic or aprotic solvent such as methanol, ethanol, acetone, and acetonitrile. The preferable temperature range is 0-5° C. SCHEME VI (SchemeRemoved) The compounds of Formula XV (Formula I, when Y = is prepared by following the reaction sequence of Scheme VI with X, A, R6, R7 R8, R9 and R10 groups as defined earlier. The starting materials for Scheme VI are compound of Formula XIV (Formula I, when Y which upon treatment with peracid such as metachloroperbenzoic acid in an organic solvent at sub zero temperature for a period varying between 2-8 hours gives the corresponding N-Oxides of Formula XV. SCHEME VII (SchemeRemoved) Scheme VII reveals the synthesis of the compounds of Formula XVII (Formula I, when Y wherein X, A, R6, R7, R8, R9 and R10 are as defined earlier. The preparation comprises condensing α,ω-dicarboximides of Formula II with ethylene diamines of Formula XVI in the presence of a base and an organic solvent at a temperature ranging from 70-80° C for a period varying between 8-24 hours to produce the corresponding compounds of Formula XVII. The suitable organic solvent is a dipolar aprotic solvent, which is selected from the group consisting of dimethyl sulfoxide, N, N-dimethylformamide, sulfolane, dimethyl acetamide, hexamethyl phosphoramide and N-methyl-2-pyrrolidone. The reaction is carried out in the presence of an inorganic base, preferably selected from the group consisting of potassium carbonate and sodium carbonate. The preferable temperature conditions for the reaction are 70-80° C. SCHEME VIII (SchemeRemoved) The compounds of Formula XVIII are alkylated in, the presence of an inorganic base and organic solvent at a temperature ranging between 20-150° C for a period varying between 5-24 hours to give the compounds of Formula XIX (Formula I, when Y = with X, A, R4, R5, R6, R7 R8, R9 and R10 are the same as defined earlier. The suitable organic solvent is a dipolar aprotic solvent which is selected from the group consisting of dimethylsulfoxide, N,N-dimethylformamide, sulfolane, dimethylacetamides, hexamethyl phosphoramide and N-methyl-2-pyrrolidone. The reaction is carried out in the presence of an inorganic base, preferably selected from the group consisting of potassium carbonate, sodium carbonate and sodium hydride. The preferable temperature conditions for the reaction are 120-150° C. SCHEME IX (SchemeRemoved) The compounds of Formula XVIII are treated with oxalyl chloride in the presence of an organic base and organic solvent at temperature ranging between 0-20° dioxopiperazine of Formula XX (Formula I, when Y= with X, A, R4,5,6,7)7a-hexahydro-lH-isoindole-1,3 (2H)-dione hydrochloride; m.p. 190-194° C, 2-[3-{4-(2-Ethoxyphenyl)piperazin~l-yl} propyl]-5-hydroxy-3a,4,5,6,7,7a-hexahydro-lH-isoindole-1,3 (2H)-dione hydrochloride; m.p. 210-213° C, 2-[3-{4-(2-Isopropoxyphenyl) piperazin-1-yl} propyl]-5-chloro-6-hydroxy-3a,4,5,6,7,7a-hexahydro-lH-isoindole-l,3 (2H)-dione hydrochloride; m.p. 160-164°C, 2-[3-{4-(2-(2,2,2-Trifluoroethoxy)phenyl)piperazin-l-yl}propyl]-5,6-epoxy-3a,4,5,6,7,7a-hexahydro-lH-isoindole-l,3(2H)-dione; m.p. oil, 2-[3-{4-(2-(2,2,2-Trifluoroethoxy)phenyl)piperazin-l-yl}propyl]-5-hydroxy-3a,4,5,6,7,7a-hexahydro-lH-isoindole-l,3(2H)-dione hydrochloride; m.p. 183-186°C. EXAMPLE 5 (Scheme V) Preparation of 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-5,6-dihydroxy-3a,4,5,6,7,7a-hexhydro-lH-isoindole-l,3 (2H)-dione hydrochloride 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-3a,4,7,7a-tetrahydro-lH-isoindole-1,3 (2H)-dione hydrochloride (1.8g, 4mmol), prepared using the procedure described in Example-1, was dissolved in ethanol (36 ml) and cooled to 0-5° C. Aqueous sodium hydroxide solution (O.l6g in 5 ml, 4mmol) was added followed by addition of aqueous solution of potassium permanganate (0.76g, 4.8 mmol) at 0-5° C and stirred for 4 hours at the same temperature. After the reaction was over, the precipitated magariese dioxide was filtered, washed with dichloromethane (25 ml). The solvent was removed under reduced pressure, water (50 ml) was added and extracted with dichloromethane (2x50 ml). The organic phase was dried over anhydrous sodium sulphate, concentrated in vacua and the residue thus obtained was purified by chromatography on silica gel using 10% methanol in dichloromethane as eluent to afford 0.55g (30.7%) of the product. The hydrochloride salt of the title compound was prepared in quantitative yield by the addition of molar quantity of ethanolic hydrogen chloride solution to a ethanolic solution of free base and the resultant precipitate was collected by filtration; m.p. 213-216°C MS m/z : 446.3 (MH+) IRKBrcm-1: 1693.4 (x=0) 1HNMR (300 MHz, DMSO-d6) δ:1.27 (6H, d), 1.66-1.70 (2H, m), 1.89-1.93 (4H, m), 2.93-3.16 (8H, m), 3.36-3.50 (8H, m), 4.57-4.65 (1H, m), 6.83-6.98 (4H, m) An illustrative list of the compounds of the invention which were synthesised by the above method is given below: 2-[3-{4-(2-Ethoxyphenyl)piperazin-l-yl}propyl]-5,6-dihydroxy-3a)4,5,6,7,7a-hexahydro-lH-isoindole-1,3 (2H)-dione ; m.p, low melting semisolid, 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-5,6-dihydroxy-3a,4,5,6,7,7a-hexahydro-lH-isoindole-1,3 (2H)-dione ; m.p. low melting semisolid, 2-[3-{4-(2-Ethoxyphenyl)piperazin-l-yl}propyl]-5,6-dihydroxy-3a,4,7,7a-tetrahydro-lH-isoindole-1,3 (2H)-dione hydrochloride; m.p. 222-225° C, EXAMPLE 6 (Scheme VI) Preparation of 2-[3-{4-(2-Ethoxyphenyl)piperazin-l-yl,l-N-oxide}propyl> 3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione. 2-[3-{4-(2-Ethoxyphenyl)piperazin-l-yl}propyl]-3a,4,7,7a-tetrahydro-lH-isoindole-1,3 (2H)-dione (0.5 g, 1.26 mmol), prepared by the method as described in Example-I, was dissolved in dichloromethane (10 ml) and cooled to 0° C. A solution of m-chloroperbenzoic acid (0.217g, 1.26 mmol) in dichloromethane (5 ml) was then added slowly over a period of 10 minutes, and the reaction mixture was further stirred for 2 hours at 0-5° C and then left at room temperature overnight. After the reaction was over, it was poured into aqueous potassium carbonate solution (5%, 30 ml). The organic layer was separated, dried over sodium sulphate, and concentrated. The crude product was purified by chromatography on silica gel, using 10% methanol in dichloromethane as eluent to afford the title compound Yield 0.1 Ig (21%) m.p. 75-80° C, IRKBrcm-1 : 1694 (c=0) MSm/z: 414(MH+) 1HNMR (300 MHz, CDC13) δ: 1.44 (SH, t), 2.24-2.65 (6H, m), 3.11 (2H, t), 3.22-3.23 (4H, m), 3.29-3.44 (4H, m), 3.62-3.66 (4H, m), 4.06-4.09 (2H, q), 5.90-5.92 (2H, m), 6.85-7.02 (4H, m). An illustrative list of the compounds of the invention which were synthesised by the above method is given below: 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl, l-N-oxide}propyl]-3a,4,7,7a-tetrahydro-lH-isoindole-1,3 (2H)-dione; m.p. 85-89° C, 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl,l,4-N,N-dioxide}propyl]-3a,4,7,7a-tetrahydro-!H-isoindole-l,3-(2H)-dione; m.p. 178-180°C, 2-[3-{4-(2-Ethoxyphenyl)piperazin-l-yl,l,4-N,N-dioxide}propyl]-3a-4,7,7a-teti-ahydro-!H-isoindole-l,3(2H)-dione; m.p, 176-178°C, 2-[3-{4-(2-Hydroxyphenyl)piperazin-l-yl, l-N-oxide}propyl]-3a,4,7,7a-tetrahydro-lH-isoindole-1,3 (2H)-dione; m.p. 198-202° C, l-[4-(2-Methoxyphenyl)piperazin-l-yl-4-N-oxide]-3-(2,6-dioxopiperidin-l-yl]propane; m.p. 190-194° C, 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl, l-N-oxide}propyl]-3a,4,7,7a-tetrahydro-lH-isoindole-1,3 (2H)-dione, 2- [3- {4-(2-Isopropoxyphenyl)piperazin-1 -yl, 1 -N-oxide}propyl]-2-hydroxypropyl] -3a,4,7,7a-tetrahydro-lH-isoindole-l,3 (2H)-dione hydrochloride; m.p. 191-197° C, l-[4-(2-Methoxyphenyl)piperazin-l-yl,l-N-oxide]-3-(2,6-dioxopiperidin-l-yl]-2-hydroxypropane; m.p. 178-182 C, l-[4-(2-Hydroxyphenyl)piperazin-l-yl,l-N-oxide]-3-(2,6-dioxopiperidin-l-yl]propane; m.p. 186-190° C. EXAMPLE 7 (Scheme VII) Preparation of 2-[[N-{N'-(2-Isopropoxyphenyl)aminoethyl}aminopropyl] -3a,4, 7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride A mixture of l-(3-bromopropyl)-cis-3a, 4,7,7a-tetrahydrophthalimide (6.0g, 22 mmol), N- (ß-aminoethyl)-oisopropoxy aniline (4.27g, 22 mmol) and potassium carbonate (3.0g, 22 mmol) in N, N-dimethyl formamide (30 ml) was stirred at 30-40° C for about 24 hrs. After the reaction was over, reaction mixture was poured in cold water (300 ml) and extracted with ethyl acetate (2x100 ml). The combined ethyl acetate layer was washed with water (2x100 ml), dried over anhydrous sodium sulphate, and concentrated in vacuo to yield crude oil. The crude product was purified by column chromatography on silica gel, using dichloromethane/methanol (9/1, v/v) as eluent to afford the desired compound as an oil. The compound thus obtained was converted into its hydrochloride salt as off white solid m. p. 168-170° C. Yield 5.5 g (64%) MS m/z 386.5 (MH+), IR KBr cm'1 1702.9 (C=O). 1H NMR (CDC13) δ; 1.37-1.39 (6H, d), 2.14-2.19 (4H, m), 2.53-2.58 (2H, b s), 3.11 (2H, b s), 3.25 (2H, b s), 3.47-3.49 (2H, m), 3.76 (2H, m), 4.53-4.62 (1H, m), 5.85-5.89 (2H, m), 6.83-6.95 (4H, m). An illustrative list of the compounds of the invention which were synthesised by the above method is given below: l-[N-(P-aminoethyl)-2-methoxyaniline]-3-[2,6-dioxopiperidin-l-yl]propane hydrochloride ; m.p. 198-201°C. EXAMPLE 8 (Scheme VIII) Preparation of 2-[[N-{N'-(2-Isopropoxyphenyl) aminoethyl}hydroxyethyl] aminopropyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride; The compound resulting from Example 7 (1g, 2.6 mmol) was dissolved in N, N-dimethylformamide (10 ml). To this solution chloroethanol (0.209g, 2.6 mmol) was added, followed by anhydrous potassium carbonate (0.36g, 2.6 mmol). The reaction mixture was heated to 120-124° C for 4 hrs. After the reaction was over, reaction mixture was poured into cold water (100 ml) and extracted with ethyl acetate (2x100 ml). The combined ethyl acetate layer was washed with water (2x100 ml) and dried over anhydrous sodium sulphate. The organic phase was concentrated in vacua and purified by column chromatography on. silica gel, using dichloromethane/methanol (90/10, v/v) as eluent to give the desired compound as an oil. The compound thus obtained was converted into its hydrochloride salt as off white solid; m. p. 135-138° C Yield 0.75g (68%) MS m/z 429.9 (MH+), IR KBr cm'1 1692.2 (C=O)., 3417 (OH) 'H NMR (CDC13) 5: 1.34-1.36 (6H, d), 2.16-2.22 (4H, m), 2.57-2.62 (2H, b d), 3.15-3.21 (4H, m), 3.27-3.31 (4H, m), 3.54-3.58 (2H, m), 3.77-3.79 (2H, m), 3.98 (2H, b s), 4.51-4.59 (1H, m), 5.89 (2H, b s), 6,61-6.73 (2H, m), 6.78-6.88 (2H, m). An illustrative list of the compounds of the invention which were synthesised by the above method is given below: 2-[N-{N'-(2-Isopropoxyphenyl)aminoethyl} acetylaminopropyl]-3a,4,7,7a-tetrahydro-lH-isoindole-1,3 (2H)-dione hydrochloride; m.p. 134-137° C, 2-[N-{N'-(2-Isopropoxyphenyl)acetylaminoethyl}aminopropyl]-3a,4,7,7a-tetrahydro-lH-isoindole-1,3 (2H)-dione hydrochloride; m.p. 157-160° C, 2- [N- {N'-(2-Isopropoxyphenyl)aminoethyl} acetaldehyde-aminoprop yl] -3 a,4,7,7a-tetrahydro-lH-isoindole-1,3 (2H)-dione, 2-[N-{N'-(2-Isopropoxyphenyl)aminoethyl}aminopropyl-N-N'-(bishydroxyethyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3 (2H)-dione, 2-[N-{N'-(2-Isopropoxyphenyl)aminoethyl}ethylacetate-aminopropyl]-3a!4,7,7a-tetrahydro-lH-isoindole-1,3 (2H)-dione, 2-[N-{N'-(2-Isopropoxyphenyl)aminoethyl}formylaminopropyl]-3a,4,7,7a-tetrahydro-lH-isoindole-1,3 (2H)-dione, 2-[3-{4-(2-Isopropoxyphenyl)piperazin-3-oxo-l-yl}propyl]-3a,4,7,7a-tetrahydro-lH-isoindole-1,3 (2H)-dione, 1-[N, N-{N'-(2-Methoxyphenyl)aminoethyl}-2-hydroxyethyl]-3-(2,6-dioxopiperidin-l-yl]aminopropane hydrochloride; m.p. 175-178° C, 2- [3 - {3-(2-Isopropoxyphenyl)imidazolidon- 1-yl }propyl]-3 a,4,7,7 a-tetrahydro- 1H-isoindole-1,3 (2H)-dione, 2-[N-{N'-(2-Isopropoxyphenyl)aminoethyl}arninopropyl-N'-(P-hydroxyethyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3 (2H)-dione hydrochloride, 2-[N-{N'-(2-Isopropoxyphenyl)aminoethyl}acetylaminopropyl]-3a,4,7,7a-tetrahydro-lH-isoindole-1,3 (2H)-dione. EXAMPLE 9 (Scheme - IX) Preparation of 2-[3-{4-(2-Isopropoxyphenyl)-2,3-dioxopiperazin-l-yl}-propyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione; To a solution of Compound No. 42 (Example 7) (0.5 g, 1.298 mmol) in dichloromethane was added triethylamine (0.197 g, 1.97 mmol) and the resulting reaction mixture was cooled to -10° C; followed by dropwise addition of oxalyl chloride (0.247 g, 1.94 mmol). The reaction temperature was raised to room temperature and stirred for 1 hr. After completion of the reaction, it was quenced by adding water (10 ml) to it, and then it was extracted with ethyl acetate (2x10 ml).The combined organic layer was concentrated under reduced pressure to yield a crude oil. The crude product was purified by column chromatography on silica gel (60-120 mesh), using dichloromethane/methanol (9.8:0.2) as an eluent to afford the product as an oil. MS m/z 440 (MET"), 1H NMR (CDC13) δ: 1.32-1.34 (6H, d), 1.89-1.94 (2H, m), 2.17-2.25 (2H, m), 2.60-2.63 (2H, m), 3.10-3.12 (2H, m), 3.48-3.57 (4H, m), 3.64-3.67 (2H, m), 3.80-3.82 (2H, m), 4.56-4,60 (1H, m), 5.83-5.92 (2H, m), 6.87-6.98 (4H, m). EXAMPLE 10 (Scheme X) Preparation of 2-[3-{4-(24sopropoxyphenyl)plperazin-l-yl}propyl]-4,7-diacetoxy-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dionehydrochloride; A mixture of l-amino-3-[4-(2-isopropoxyphenyl)piperazin-l-yl]propane(lg,3.6 mmol) and maleic anhydride (0.36 g,3.6 mmol) was refluxed in toluene for 3 hrs with azeotropic removal of water . After the completion of the reaction, the solvent was removed under reduced pressure and the residue thus obtained was column chromatographed to afford an oily product (yield 0.82 g, intermediate) The mixture of this intermediate (0.8, 2.24 mmol) and l,4-diacetoxy-l,3-butadiene (0.38 g, 2.24 mmol) were refluxed in toluene for 8 hrs. After completion of the reaction, the solvent was removed under reduced pressure. The crude product was purified by chromatography using dichloromethane methanol (9.9:0.1) as eluent. The oily product thus obtained was finally converted into its hydrochloride salt (m.p. 176-177° C). IR (KBr cm-1): 1703.2 (C=O), 1741.3 (C=O). MS m/z : 528 (MH+) 1H NMR (CDCla) δ : 1.35-1.37 (6H,d), 2.13 (6H,s), 2.20-2.23(2H,m),3.01(4HJbr s), 3.52-3.56 (6H,m)!3.61-3.63(2H,m),3.68-3.69(2H,m),4.57-4.61(lH,m),5.42-5.43(2H,m), 6.16 (2H,m),6.85-6.90(3H,m),6.99-7.02(lH,m). An illustrative list of the compounds of the invention which were synthesised by the above method is given below: 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-5,6-dimethoxy-3a,4,7,7a-tetrahydro-lH-isoindole-1,3 (2H)-dione hydrochloridejm.p. 153-155°C, 2-[3- {4-(2-Isopropoxyphenyl)piperazin-1 -yl }propyl] -4,7-diphenyl-3 a,4,7,7 a-tetrahydro-lH-isoindole-1,3 (2H)-dione hydrochloride;m.p. 193-194° C, 2-[3-{4-(2-methoxyphenyl)piperazin-l-yl}propyl]-4,7-diphenyl-3a,4,7,7a-tetrahydro-lH-isoindole-1,3 (2H)-dione hydrochloride;m.p. 224-225° C, 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-4-hydroxy-3a,4,5,6,7,7a-hexahydro-lH-isoindole-1,3 (2H)-dione hydrochloride;m.p. 163-165° C, 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-5,6-dimethoxy-3a,4,5,6,7,7a-hexahydro-lH-isoindole-1,3 (2H)-dione hydrochloride;m.p. 143-146° C. Pharmacological Testing Results Receptor Binding Assays Receptor binding assays were performed using native a-adrenoceptors. The affinity of different compounds for ecu and (XIB adrenoceptor subtypes was evaluated by studying their ability to displace specific [3H] prazosin binding from the membranes of rat submaxillary and liver respectively (Michel et al, Br J Pharmacol, 1989; 98:883). The binding assays were performed according to U'Prichard et al. (Eur J Pharmacol, 1978; 50:87 with minor modifications. Submaxillary glands were isolated immediately after sacrifice. The liver was perfused with buffer (Tris HCI 50 mM, NaCl l00mM, 10 mM EDTA pH 7.4). The tissues were homogenised in 10 volumes of buffer (Tris HCI 50 mM, NaCl lOOmM, 10 mM EDTA pH 7.4). The homogenate was filtered through two layers of wet gauge and filtrate was centrifuged at 500 g for 10 min. The supernatant was subsequently centrifuged at 40,000 g for 45 min. The pellet thus obtained was resuspended in the same volume of assay buffer (Tris HCI 50 mM, 5 mM EDTA pH 7.4) and was stored at -70° C until the time of assay. The membrane homogenates (150-250 fig protein) were incubated in 250 nl of assay buffer (Tris HCI 50 mM, EDTA 5 mM, pH 7.4) at 24-25° C for 1 hour. Non specific binding was determined in the presence of 300 nM prazosin. The incubation was terminated by vacuum filtration over GF/B fibre filters. The filters were then washed with ice cold 50mM Tris HCI buffer (pH 7.4). The filtermats were dried and bound radioactivity retained on filters was counted. The IC50 and Kd were estimated by using the non-linear curve-fitting program using G Pad Prism software. The value of inhibition constant Ki was calculated from competitive binding studies by using Cheng & Prusoff equation (Cheng & Prusoff, Biochem Pharmacol, 1973,22: 3099-3108), Ki = IC50 /(1+L/Kd) where L is the concentration of [3H] prazosin used in the particular experiment (Table I). In Vitro Functional Studies In order to study selectivity of action of these compounds towards different a-adrenoceptor subtypes, the ability of these compounds to antagonise ((XID) prostate (ecu) and spleen (α13) was studied. Aorta and spleen tissues were isolated from urethane anaesthetized (1.5 g/kg) male wister rats. Isolated tissues were mounted in organ bath containing Rrebs Henseleit buffer of the following composition (mM): NaCl 118; KCI 4.7; CaCl2 2.5; MgSO4 7H20 1.2; NaHCO3 25; KH2PO4 1.2; glucose 11.5. Buffer was maintained at 37° C and aereated with a mixture of 95% 02 and 5% CO2. A resting tension of 2g (aorta) or 1g (spleen and prostate) was applied to tissues. Contractile response was monitored using a force displacement transducer and recorded on chart recorders. Tissues were allowed to equilibrate for 2 hours. At the end of equilibration period, concentration response curves to norepinephrine (aorta) and phenylepinephrine (spleen and prostate) were obtained in the absence and presence of tested compound (at concentration of 0.1,1 and 10 mM). Antagonist affinity was calculated and expressed as pKs values in Table n. In Vivo Uroselectivitv Study In order to assess the uroselectivity in vivo, the effects of these compounds were studied on mean arterial pressure (MAP) and intraurethral pressure (IUP) in conscious beagle dogs as per the method of Brune et al. (Pharmacol., 1996, 53:356). Briefly, male dogs were instrumented for chronic continuous measurement of arterial blood pressure by implanting a telemetry transmitter (TL11M2-D70-PCT, Data Sci. International, St. Paul, MN USA) into the femoral artery, two weeks prior to the study. During the recovery period, the animal was acclimatized to stay in the sling restraint. On the day of testing, overnight fasted animal was placed in the sling restraint. A Swan-Ganz. Balloon tipped catheter was introduced into the urethra at the level of prostate and the balloon was inflated (Brune. et. al. 1996). After recording the base line readings, effect of 16µg/kg, phenylephrine (i.v.) on MAP and IUP was recorded. The response of phenylephrine to MAP and IUP were recorded at 0.5, 1, 2, 3, 4, 6, 9 and 24 hours after the oral administration of vehicle or the test drug. The changes in MAP were recorded on line using Dataquest Software (Data Sci. International, St. Paul, MN. USA). The change in phenylephrine response on MAP and IUP administration after the test drug administration was calculated as percent change of that of control values. Area under curve was calculated, and the ratio of the values for MAP and IUP was used for calculating the uroselectivity (Table III). Table I: Radioligand Binding Studies: Affinity of compounds for Alpha-1 Adrenoceptor Subtypes (TableRemoved) Table II: In Vitro Functional Assays (TableRemoved) Table III; In Vivo Uroselectivitv Studies in Conscious Beagle Dogs (TableRemoved) While the present invention has been described in terms of its specific embodiments, certain modifications and equivalents will be apparent to those skilled in the art and are intended to be included within the scope of the present invention. We Claim; 1. A compound having the structure of Formula I (Formula Removed) and its pharmaceutically acceptable salts, enantiomers, diastereomers, N-oxides, prodrugs, metabolities, polymorphs, or pharmaceutically acceptable solvates, wherein X is selected from the group consisting of (Formula Removed) where the points of attachment are depicted by hashed bonds, and where one point of attachment is bonded to the carbonyl adjacent to the nitrogen and the second point of attachment is bonded to the other carbonyl; (Formula Removed) where m is one of the integers 2,3 or 4; RH is independently selected from H, F, Cl, Br, I, OH, straight or branched lower (C1-6) alkyl, lower (C1-6) alkoxy, lower (Ci-e) perhaloalkyl, lower (C1-6) perhaloalkoxy; Y is selected from the group consisting of (Formula Removed) R1 and R2 are independently selected from H, OH, CN, NO2, Cl, F, Br, I, OR3> COR3) OCOR3, COOR3 NH2, N (R*, R5), lower (C1-4) alkyl, lower (C1-4) alkoxy, lower (C1-4 alkylthio, lower (CM) perhaloalkyl, , lower (C1-6) perhaloalkoxy; lower (CM) alkoxy substituted with one or more of F, Cl, Br, I, OH, OR3 or optionally substituted groups selected from aryl, aryloxy, aralalkyl, heterocyclyl or heteroaryl the said substituents being H, F, Cl, Br, I, OH, OR3, lower (CM) alkyl , lower (C1-4) alkyl substitued with one or more of F, Cl, Br, I, OH or OR3, wherein R3, is selected from the group consisting of H , straight or branched C1- C6 alkyl or perhaloalkyl; R4 and R5 are independently selected from the group consisting of H, CHO, substituted or unsubstituted lower (CM) alkyl, lower (CM) alkoxy, COR3, COOR3, CH2CH(OR3)2, CH2COOR3, CH2CHO or (CH2)2OR3 where R3 is the same as defined above; R6 R7, R8, R9 and R10 are independently selected from H, OH, CN, NO2, Cl, F, Br, I, straight or branched lower (CM) alkyl optionally substituted with one or more halogens, lower (C1-4) alkoxy optionally substituted with one or more halogens, (C3-6) cycloalkoxy, NH2, N-lower(C1-4) alkylamino, N, N-di-lower (C1-C4) alkylamino, N-lower alkyl(C1-C4)amino carbonyl, hydroxy substituted with aromatic or non-aromatic five or six membered ring, phenyl, phenyl substituted by Cl, F, Br, I, NO2, NH2 (C1-4) alkyl or (CM) alkoxy (C1-4) perhaloalkyl, (CM) perhaloalkoxy wherein the broken line (-—) is a single bond or no bond. 2. A compound selected from the group consisting of: - l-[4-(2-Hydroxyphenyl) piperazin-l-yl]-3-(2,6-dioxopiperidin-l-yl) propane hydrochloride, - 2-[3-{4-(2-(2,2,2-Trifluoroethoxy) phenyl) piperazin-l-yl}propyl]-3a, 4,7,7a- tetrahydro-lH-isoindole-1,3 (2H)-dione hydrochloride, - l-[4-{2-(2,2,2-Trifluoroethoxy)phenylpiperazin-l-yl]-3-(2,6-dioxopiperidin- l-yl)propanehydrochloride, 2-[3-{4-(2-Ethoxyphenyl)piperazin-l-yl, 1 -N-oxide} propyl]-3a,4,7,7a-tetrahydro-lH-isoindole-1,3 (2H)-dione, l-[4-(2-Ethoxyphenyl)piperazin-l-yl]-3-(2,6-dioxopiperadin-l-yl)ethane hydrochloride, 2-[3-{4-(2-Methoxyphenyl)piperazin-l-yl}-2-hydroxypropyl]-3a,4,7,7a-tetrahydro-lH-isoindole-1,3 (2H)-dione hydrochloride, 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}-2-hydroxypropyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride, 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl, l-N-oxide}propyl]-3a,4,7,7a-tetrahydro-lH-isoindole-1,3 (2H)-dione, 2-[3- {4-(2-Isopropoxyphenyl)piperazin- l-yl-1,4-N,N-dioxide} propyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3-(2H)-dione, 2-[3-{4-(2-Ethoxyphenyl)piperazin-l-yl,l,4-N,N-dioxide}propyl]-3a-4,7,7a-tetrahy dr o- IH-isoindole-1,3(2H)-dione, 2-[3-{4-(2-Ethoxyphenyl)piperazin~l-yl}-2-hydroxypropyl]-3a,4,7,7a-tetrahydro- IH-isoindole-1,3-(2H)-dione hydrochloride, 2-[3-{4-(2-Ethoxyphenyl)piperazin-l-yl}propyl]-5,6-dihydroxy-3a,4,5,6,7,7a-hexahydro-lH-isoindole-l,3(2H)-dione, 2- [3- {4- (2-Isopropoxyphenyl)piperazin-1 -yl} propyl] -5,6-dihy droxy-3a,4,5,6,7,7a-hexahydro-lH-isoindole-l,3(2H)-dione, 2-[3-{4-(2-Hydroxyphenyl)piperazin-l-yl}-2-hydroxypropyl]-3a,4,7,7a-tetrahydro- IH-isoindole-1,3(2H)-dione hydrochloride, 2-[2-{4-(2-Ethoxyphenyl)piperazin-l-yl}ethyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride, 2- [2- {4-(2-(2,2,2-Trifluoroethoxy)phenyl)piperazin-1 -yl} ethyl] -3 a,4,7,7a-tetrahydro- IH-isoindole-1,3 (2H)-dione hydrochloride, 2-[3-{4-(2-Ethoxyphenyl)piperazin-l-yl}propyl]-5-chloro-6-hydroxy-3a,4,5,6,7,7a-hexahydro-lH-isoindole-l,3(2H)-dione hydrochloride, 2-[3-{4-(2-Ethoxyphenyl)piperazin-l-yl}propyl]-5-hydroxy-3a,4,5,6,7,7a-hexahydro-lH-isoindole-1,3 (2H)-dione hydrochloride, 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-5,6-epoxy-3a,4,5,6,7,7a-hexahydro-lH-isoindole-l,3(2H)-dione, 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-5-hydroxy-3a,4,5,6,7,7a-hexahydro-lH-isoindole-l,3(2H)-dione, 2-[3-{4-(2-Isopropoxy-5-hydroxyphenyl)piperazin-l-yl}propyl]-3a,4,7,7a-tetrahydro-IH-isoindole-1,3 (2H)-dione hydrochloride, 2-[3-{4-(2-Hydroxyphenyl)piperazin-l-yl, l-N-oxide}propyl]-3a,4,7,7a-tetrahydro- IH-isoindole-1,3 (2H)-dione, 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-5,6-dihydroxy-3a,4,5,6,7,7a, hexahydro-lH-isoindole-1,3 (2H)-dione-hydrochloride, 2-[3-{4-(2-Ethoxy-5-hydroxyphenyl)piperazin-l-yl}propyl]-3a,4,7,7a-tetrahydro- IH-isoindole-1,3 -(2H)-dione hydrochloride, 2-[3-{4-(2-Isopropoxy-4-nitrophenyl)piperazin-l-yl}propyl]-3a,4,7,7a-tetrahydi-o-!H-isoindole-l,3(2H)-dione hydrochloride, 2-[3-{4-(24sopropoxy-4-aminophenyl)piperazin-l-yl}propyl]-3a,4,7,7a-tetrahydro- IH-isoindole-1,3(2H)-dione hydrochloride, 2-[3-{4-(2-isopropoxy-6-hydroxyphenyl)piperazin-l-yl}propyl]-3a-,7,7a-tetrahydro- IH-isoindole-1,3(2H)-dione hydrochloride, 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-5-chloro-6-hydroxy-3a,4,5,6,7,7a-hexahy dro-1H-isoindole-1,3(2H)-dione hydrochloride, l-[4-(2-Isopropoxyphenyl)piperazin-l-yl]-2-hydroxy-3-(2,6-dioxopiperidin-l-yl)propane hydrochloride, 2- [3- {4-(2-Isopropoxyphenyl)piperazin-1 -yl} -2-hydroxypropyl] -5,6-epoxy-3 a,4,5,6,7,7a-hexahydro- IH-isoindole-1,3(2H)-dione, 2-[3 - {4-(2-(2,2,2-Trifluoroethoxyphenyl)piperazin-1 -yl} -2-hydroxypropyl] -3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride, 2-[3-{4-(2-(2,2,2-Trifluoroethoxy)phenyl)piperazin-l-yl}propyl]-5,6-epoxy-3a,4,5,6,7,7a-hexahydro-lH-isoindole-l,3(2H)-dione, 2-[3-{4-(2-(2,2,2-Trifluoroethoxy)phenyl)piperazin-l-yl}propyl]-5-hydroxy-3a,4,5,6,7,7a-hexahydro-lH-isoindole-l,3(2H)-dione hydrochloride, 2-[3- {4-(2-(2,2,2-Trifluoroethoxy)phenyl)piperazin- 1-yl} -2-hydroxypropyl]-5,6-epoxy-3 a,4,5,7,7 a-hexahydro-1 H-isoindole-1,3 (2H)-dione, 2- [3 - {4-(2-Isopropoxy-3 -hydroxyphenyl)piperazin-1 -yl} propyl] -3 a,4,7,7 a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride, l-[4-(2-Isopropoxy-5-hydroxyphenyl)piperazin-l-yl]-3-(2,6-dioxopiperdin-l-yl)piperazin-l-yl]-3-(2,6-dioxopiperidin-l-yl)propane hydrochloride, l-[4-(2-Isopropoxy-6-hydrxyphenyl)piperazin-l-yl]-3-(2,6-dioxopiperdin-l-yl)propane hydrochloride, l-[4-(2-Isopropoxy-3-hydroxyphenyl)piperazin-l-yl]-3-(2,6-dioxopiperidin-l-yl)propane hydrochloride, l-[4-{2-(2,2,2-Trifluoroethoxy)phenyl)piperazin-l-yl]-2-hydroxy-3-(2,6-dioxopiperidin- l-yl)propane hydrochloride, 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-4-acetoxy-3a,4,7,7a-tetrahydro- IH-isoindole-1,3 (2H)-dione hydrochloride, 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-4-hydroxy-3a,4,7,7a-tetrahydro- IH-isoindole-1,3 (2H)-dione hydrochloride, 2-[N-{N'-(2-Isopropoxyphenyl)aminoethyl}aminopropyl]-3a,4,7,7a-etrahydro- IH-isoindole-1,3 (2H)-dione hydrochloride, 2-[3-{4-(2-Cyclopentyloxyphenyl)piperazin-l-yl}propyl]-3a,4,7,7a-tetrahydro- IH-isoindole-1,3(2H)-dione hydrochloride, l-[4-(2-hydroxyphenyl)piperazin-l-yl]-2-hydroxy-3-(2,6-dioxopiperidin-l-yl] propane hydrochloride, 2-[3-{4-(2-Biphenyl)piperazin -l-yl}propyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride, 2-[N- {N' -(2-Isopropoxyphenyl) aminoethyl} acetylaminopropyl] - 3a,4,7.Va-tetrahydro-IH-isoindole-1,3 (2H)-dione hydrochloride, 2-[N-{N'-(2-Isopropoxyphenyl) acetylarnmoethyl}arninopropyl]-3a,4,7,7a-tetrahydro- IH-isoindole-1,3 (2H)-dione hydrochloride, 2-[[N-{N'-(2-Isopropoxyphenyl)aroinoethyl}hydroxyethyl]aminopropyl]-3a,4, 7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride, l-[4-(2-Isopropoxyphenyl)piperazin-l-yl]-l-oxo-3-(2,6-dioxopiperidin-l-yl)propane hydrochloride, 2-[N-{N'-(2-Isopropoxyphenyl) aminoethyl Jacetaldehyde-aminopropyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione, 2-[ N-{N'-(2-Isopropoxyphenyl)aminoethyl} aminopropyl-N,N'-(bis hydroxy ethyl]- 3a,4,7,7a-tetrahydro- IH-isoindole-1,3 (2H)-dione, 2-[N- {N' -(2-Isopropoxyphenyl) aminoethyl} ethylacetate-aminopropyl] -3a,4, 7,7 a-tetrahydro- IH-isoindole-1,3 (2H)-dione, 2-[N-{N'-(2-Isopropoxyphenyl) aminoethyl}formylaminopropyl]- 3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione, 2-[3- {4-(2-Isopropoxyphenyl)piperazin-3-oxo-1 -yl Jpropyl]- 3a,4,7,7a-tetrahydro-lH-isoindole-1,3(2H)-dione, l-[4-(2-Methoxyphenyl)piperazin-l-yl-4-N-oxide]- 3-(2,6-dioxopiperidin-l-yl]propane, l-[N-{N'-(2-Methoxyphenyl)aminoethyl}-3-(2,6-dioxopiperidin-l-yl]aminopropane hydrochloride, 1 -[N-N- {N' -(2-Methoxyphenyl)aminoethyl} ]-3-(2,6-dioxopiperidin-1 -yl)aminopropane hydrochloride; 2-[3-{4-(2-Isopropoxy-4-acetylaminophenyl)piperazin-l-yl}propyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride, 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-7,7a-dihydro-lH-isoindole-1,3(2H)-dione hydrochloride, 2-[3- {4-(2-Isopropoxyphenyl)piperazin-1 -yl} -propyl]-4-hydroxy-3a,4,5,6,7,7a-hexahydro-IH-isoindole-l,3(2H)-dione hydrochloride, 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}-propyl]-exo-4,7-epoxy- 3a,4, 7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride, 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}-l-oxo-propyl]-3a,4, 7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride, 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}-l-oxo-propyl]-3a,4,5,6, 7,7a-hexahydro-lH-isoindole-l,3(2H)-dione hydrochloride, 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl,4-N-oxide}propyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione, 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl,l-N-oxide}2-hydroxypropyl]-3a,4, 7,7a-tetrahydro-IH-isoindole-1,3(2H)-dione, 2-[3-{4-(2-ethoxyphenyl)piperazin-l-yl }propyl]-5,6-dihydroxy-3a,4,7,7a-tetrahydro-lH-isoindoIe-l,3(2H)-dione hydrochloride, 2-[3-{3-(2-Isopropoxyphenyl)imidazolidon- 1-yl }propyl]-3a,4, 7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione, 2-[ N-{N'-(2-Isopropoxyphenyl)aminoethyl} aminopropyl- N'-(P- hydroxyethyl]-3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride, l-[4-(2-Methoxyphenyl)piperazin-l-yI-l-N-oxide]- 3-(2,6-dioxopiperidin-l-yl]-2-hydroxypropane, l-[4-(2-Hydroxyphenyl)piperazin-l-yl-l-N-oxide]- 3-(2,6-dioxopiperidin-l-yl]propane, 2- [3 - {4-(2-Isopropoxyphenyl)-2,3-dioxopiperazin- 1-yl}-I -oxo -propyl] -3 a,4, 7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione, 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-4,7-dihydroxy-3a,4, 7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione, 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-4,7-diacetoxy-3a,4, 7,7a-tetrahydro- IH-i soin dole-1,3 (2H)-dione h ydrochlori de, 2-[N-{N' -(2-Isopropoxyphenyl) aminoethyl Jethylaminopropyl]- 3a,4,7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione, 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-5,6-dimethoxy-3a,4, 7,7a-tetrahydro- IH-isoindole-1,3 (2H)-dione hydrochloride, 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-5,6-dimethoxy-3a,4,5,6, 7,7a-hexahydro-lH-isoindole-l,3(2H)-dione hydrochloride, 2-[3-{4-(2-Isopropoxyphenyl)piperazin-l-yl}propyl]-4,7-diphenyl-3a,4, 7,7a-tetrahydro-lH-isoindole-l,3(2H)-dione hydrochloride, 2-[3-{4-(2-Methoxyphenyl)piperazin-l-yl}propyl]-4,7-diphenyl-3a,4, 7,7a-tetrahydro-IH-isoindole-1,3(2H)-dione hydrochloride. 3. A method of selectively antagonizing α1-adrenergic receptors in a mammal comprising administering to said mammal a therapeutically effective amount of a compound having the structure of Formula I: (Formula Removed) and its pharmaceutically acceptable salts, enantiomers, diastereomers, N-oxides, prodrugs, metabolities, polymorphs, or pharmaceutically acceptable solvates, wherein X is selected from the group consisting of (Formula Removed) where the points of attachment are depicted by hashed bonds, and where one point of attachment is bonded to the carbon yl adjacent to the nitrogen and the second point of attachment is bonded to the other carbonyl; W is O, S, SO or SO2; (Formula Removed) where m is one of the integers 2,3 or 4; R11 is independently selected from H, F, Cl, Br, I, OH, straight or branched lower (C1-6) alkyl, lower (C1-6) alkoxy, lower (C1-6) perhaloalkyl, lower (C1-6) perhaloalkoxy; Y is selected from the group consisting of (Formula Removed) RI and R2 are independently selected from H, OH, CN, NO2, Cl, F, Br, I, OR3, COR3, OCOR3, COOR3, NH2, N (R4, R5), lower (C1-4) alkyl, lower (C1-4) alkoxy, lower (C1-4) alkylthio, lower (C1-4) perhaloalkyl, , lower (C1-6) perhaloalkoxy; lower (C1-4) alkoxy substituted with one or more of F, Cl, Br, I, OH, OR3 or optionally substituted groups selected from aryl, aryloxy, aralalkyl, heterocyclyl or heteroaryl the said substituents being H, F, Cl, Br, I, OH, OR3, lower (C1-4) alkyl, lower (C1-4) alkyl substitued with one or more of F, Cl, Br, I, OH or OR3) wherein R3l is selected from the group consisting of H , straight or branched C1-C6 alkyl or perhaloalkyl; R4 and R5 are independently selected from the group consisting of H, CHO, substituted or unsubstituted lower (C1-4) alkyl, lower (C1-4) alkoxy, COR3, COOR3, CH2CH(OR3)2, CH2COOR3, CH2CHO or (CH2)2OR3 where R3 is the same as defined above; Re, R?, Rg, R9 and RIO are independently selected from H, OH, CN, NO2, Cl, F, Br, I, straight or branched lower (C1-4) alkyl optionally substituted with one or more halogens, lower (C1-4) alkoxy optionally substituted with one or more halogens, (C3-6) cycloalkoxy, NH2, N-lower(C1-4) alkylamino, N, N-di-lower (C1-C4) alkylamino, N-lower alkyl(C1-C4)amino carbonyl, hydroxy substituted with aromatic or non-aromatic five or six membered ring, phenyl, phenyl substituted by Cl, F, Br, I, NOa, NH2, (C1-4) alkyl or (C1-4) alkoxy (C1-4) perhaloalkyl, (C1-4) perhaloalkoxy wherein the broken line (-is a single bond or no bond. 4. A method of treating benign prostatic hyperplasia in a mammal comprising administering to said mammal a therapeutically effective amount of a compound having the structure of Formula I: (Formula Removed) and its pharmaceutically acceptable salts, enantiomers, diastereomers, N-oxides, prodrugs, metabolities, polymorphs, or pharmaceutically acceptable solvates, wherein X is selected from the group consisting of (Formula Removed) where the points of attachment are depicted by hashed bonds, and where one point of attachment is bonded to the carbonyl adjacent to the nitrogen and the second point of attachment is bonded to the other carbonyl; W is O, S, SO or SO2; (Formula Removed) where m is one of the integers 2,3 or 4; R11 is independently selected from H, F, Cl, Br, I, OH, straight or branched lower (C1-6) alkyl, lower (C1-6) alkoxy, lower (C1-6) perhaloalkyl, lower (C1-6) perhaloalkoxy; Y is selected from the group consisting of (Formula Removed) RI and R2 are independently selected from H, OH, CN, NO2, Cl, F, Br, I, OR3, COR3) OCOR3, COOR3 NH2 N (R4, R3), lower (C1-4) alkyl, lower (C1-4) alkoxy, lower (C1-4) alkylthio, lower (C1-4) perhaloalkyl, , lower (C1-6) perhaloalkoxy; lower (C1-4) alkoxy substituted with one or more of F, Cl, Br, I, OH, OR3 or optionally substituted groups selected from aryl, aryloxy, aralalkyl, heterocyclyl or heteroaryl the said substituents being H, F, Cl, Br, I, OH, OR3, lower (C1-4) alkyl, lower (C1-4) alkyl substitued with one or more of F, Cl, Br, I, OH or OR3, wherein R3, is selected from the group consisting of H , straight or branched C1-C6 alkyl or perhaloalkyl; R4 and R5 are independently selected from the group consisting of H, CHO, substituted or unsubstituted lower (CM) alkyl, lower (CM) alkoxy, COR3, COOR3, CH2CH(OR3)2, CH2COOR3, CH2CHO or (CH2)2OR3 where R3 is the same as defined above; R6, R7, R8, R9 and R10 are independently selected from H, OH, CN, NO2, Cl, F, Br, I, straight or branched lower (C1-4) alkyl optionally substituted with one or more halogens, lower (CM) alkoxy optionally substituted with one or more halogens, (C3-6) cycloalkoxy, NH2, N-lower(CM) alkylamino, N, N-di-lower (C1-C4) alkylamino, N-lower alkyl(C1-C4)amino carbonyl, hydroxy substituted with aromatic or non-aromatic five or six membered ring, phenyl, phenyl substituted by Cl, F, Br, I, NO2, NH2, (CM) alkyl or (CM) alkoxy (CM) perhaloalkyl, (CM) perhaloalkoxy wherein the broken line (—) is a single bond or no bond. 5. A pharmaceutical composition comprising a therapeutically effective amount of a compound as defined in claim 1 or 2 and a pharmaceutical acceptable carrier. 6. A method of selectively antagonizing α1-adrenergic receptors in a mammal comprising the step of administering to said mammal a therapeutically effective amount of the pharmaceutical composition according to claim 5. 7. A method for treating benign prostatic hyperplasia in a mammal comprising the step of administering to said mammal a therapeutically effective amount of the pharmaceutical composition according to claim 5. 8. A process for preparing a compound of Formula I, and its pharmaceutically acceptable salts, enantiomers, diastereomers, N-oxides, prodrugs, metabolities, polymorphs, or pharmaceutically acceptable solvates, which comprises reacting of compound of Formula II with a compound of Formula III as shown below: (Formula Removed) wherein X is selected from the group consisting of (Formula Removed) where the points of attachment are depicted by hashed bonds, and where one point of attachment is bonded to the carbonyl adjacent to the nitrogen and the second point of attachment is bonded to the other carbonyl; W is O, S, SO or SO2; A is -(CH2)rn-, (Formula Removed) where m is one of the integers 2,3 or 4; RH is independently selected from H, F, Cl, Br, I, OH, straight or branched lower (C1-6) alkyl, lower (C1-6) alkoxy, lower (C1-6) perhaloalkyl, lower (C1-6) perhaloalkoxy; Y is selected from the group consisting of (Formula Removed) RI and R2 are independently selected from H, OH, CN, NO2, Cl, F, Br, I, OR3, COR3, OCOR3, COOR3, NH2) N (R4, R5), lower (C1-4) alkyl, lower (C1-4) alkoxy, lower (C1-4) alkylthio, lower (C1-4) perhaloalkyl, lower (C1-6) perhaloalkoxy; lower (C1-4) alkoxy substituted with one or more of F, Cl, Br, I, OH, OR3 or optionally substituted groups selected from aryl, aryloxy, aralalkyl, heterocyclyl or heteroaryl the said substituents being H, F, Cl, Br, I, OH, OR3, lower (C1-4) alkyl, lower (C1-4) alkyl substitued with one or more of F, Cl, Br, I, OH or OR3, wherein R3, is selected from the group consisting of H , straight or branched C1- C6 alkyl or perhaloalkyl; R4 and R5 are independently selected from the group consisting of H, CHO, substituted or unsubstituted lower (C1-4) alkyl , lower (C1-4) alkoxy, COR3, COOR3, CH2CH(OR3)2 CH2COOR3, CH2CHO or (CH2)2OR3 where R3 is the same as defined above; R6, R7, R8, R9 and R10 are independently selected from H, OH, CN, NO2, Cl, F, Br, I, straight or branched lower (C1-4) alkyl optionally substituted with one or more halogens, lower (C1-4) alkoxy optionally substituted with one or more halogens, (C3-6) cycloalkoxy, NH2, N-lower(C1-4) alkylamino, N, N-di-lower (C1-C4) alkylamino, N-lower alkyl(Ci-C4)amino carbonyl, hydroxy substituted with aromatic or non-aromatic five or six membered ring, phenyl, phenyl substituted by Cl, F, Br, I, NO2, NH2, (C1-4) alkyl or (C1-4) alkoxy (C1-4) perhaloalkyl, (C1-4) perhaloalkoxy wherein the broken line (—) is a single bond or no bond. 9. The process of claim 8 wherein the reaction of compound of Formula II and Formula III is carried out in a suitable dipolar aprotic solvent, wherein the solvent is selected from the group consisting of dimethylsulfoxide, N N-dimethyl formamide, sulfolane, dimethylacetamide, hexarnethyl phosphoramide and N-methyl-2-pyrrolidone. 10. The process of claim 8 wherein the reaction of compound of Formula II and III is carried out in the presence of a suitable inorganic base wherein the base is selected from the group consisting of sodium hydride, cesium carbonate, potassium carbonate and sodium carbonate. 11. A process for preparing a compound of Formula I, and its pharmaceutically acceptable salts, enantiomers, diastereomers, N-oxides, prodrugs, metabolites, polymorphs, or pharmaceutically acceptable solvates thereof, which comprises reacting a compound of Formula IV with a compound of Formula V as shown below: (Formula Removed) wherein X is selected from the group consisting of (Formula Removed) where the points of attachment are depicted by hashed bonds, and where one point of attachment is bonded to the carbonyl adjacent to the nitrogen and the second point of attachment is bonded to the other carbonyl; W is O, S, SO or SO2, (Formula Removed) where m is one of the integers 2,3 or 4; Rn is independently selected from H, F, Cl, Br, I, OH, straight or branched lower (C1-6) alkyl, lower (C1-6) alkoxy, lower (C1-6) perhaloalkyl, lower (C1-6) perhaloalkoxy; Y is selected from the group consisting of (Formula Removed) R1 and R2 are independently selected from H, OH, CN, NO2, Cl, F, Br, I, OR3, COR3, OCOR3, COOR3, NH2, N (R4, R5), lower (C1-4) alkyl, lower (C1-4) alkoxy, lower (C1-4) alkylthio, lower (C1-4) perhaloalkyl, lower (C1-4) perhaloalkoxy; lower (C1-4) alkoxy substituted with one or more of F, Cl, Br, I, OH, OR3 or optionally substituted groups selected from aryl, aryloxy, aralalkyl, heterocyclyl or heteroaryl the said substituents being H, F, Cl, Br, I, OH, OR3, lower (CM) alkyl, lower (CM) alkyl substitued with one or more of F, Cl, Br, I, OH or OR3, wherein R3, is selected from the group consisting of H , straight or branched C1- C6 alkyl or perhaloalkyl; R4 andR5 are independently selected from the group consisting of H, CHO, substituted or unsubstituted lower (CM) alkyl , lower (CM) alkoxy, COR3, COOR3, CH2CH(OR3)2, CH2COOR3, CH2CHO or (CH2)2OR3 where R3 is the same as defined above; R6, R7, R8 R9 and R10 are independently selected from H, OH, CN, NO2, Cl, F, Br, I, straight or branched lower (CM) alkyl optionally substituted with one or more halogens, lower (CM) alkoxy optionally substituted with one or more halogens, (C3-6) cycloalkoxy, NH2, N-lower(C1-4) alkylamino, N, N-di-lower (C1-C4) alkylamino, N-lower alkyl(C1-C4)amino carbonyl, hydroxy substituted with aromatic or non-aromatic five or six membered ring, phenyl, phenyl substituted by Cl, F, Br, I, NO2, NH2, (C1-4) alkyl or (CM) alkoxy (C1-4) perhaloalkyl, (C1-4) perhaloalkoxy wherein the broken line (-—) is a single bond or no bond. 12. The process of claim 11 wherein the reaction of Formula IV and Formula V is carried out in an organic solvent selected from the group consisting of benzene, toluene, xylene, pyridine, and mixture(s) thereof. 13. A process for preparing a compound of Formula I, and its pharmaceutically acceptable salts, enantiomers, diastereomers, N-oxides, prodrugs, metabolites, polymorphs, or pharmaceutically acceptable solvates thereof, which comprises reacting a compound of Formula IE with a compound of Formula VI, as below: (Formula Removed) wherein X is selected from the group consisting of (Formula Removed) where the points of attachment are depicted by hashed bonds, and where one point of attachment is bonded to the carbonyl adjacent to the nitrogen and the second point of attachment is bonded to the other carbonyl; WisO, S,SOorSO2; (Formula Removed) where m is one of the integers 2,3 or 4; R11 is independently selected from H, F, Cl, Br, I, OH, straight or branched lower (C1-6) alkyl, lower (C1-6) alkoxy, lower (C1-6) perhaloalkyl, lower (C1-6) perhaloalkoxy; Y is selected from the group consisting of (Formula Removed) R1 and R2 are independently selected from H, OH, CN, N02, Cl, F, Br, I, OR3, COR3, OCOR3, COOR3, NH2l N (R4, R5), lower (C1-4) alkyl, lower (C1-4) alkoxy, lower (C1-4) alkylthio, lower (C1-4) perhaloalkyl, lower (C1-6) perhaloalkoxy; lower (C1-4) alkoxy substituted with one or more of F, Cl, Br, I, OH, OR3 or optionally substituted groups selected from aryl, aryloxy, aralalkyl, heterocyclyl or heteroaryl the said substituents being H, F, Cl, Br, I, OH, OR3, lower (C1-4) alkyl, lower (C1-4) alkyl substitued with one or more of F, Cl, Br, I, OH or OR3, wherein R3, is selected from the group consisting of H , straight or branched C1- C6 alkyl or perhaloalkyl; R4 and R5 are independently selected from the group consisting of H, CHO, substituted or unsubstituted lower (C1-4) alkyl , lower (C1-4) alkoxy, COR3, COOR3, CH2CH(QR3)2, CH2COOR3, CH2CHO or (CH2)2OR3 where R3 is the same as defined above; R6, R7, R8 R9 and R10 are independently selected from H, OH, CN, NO2, Cl, F, Br, I, straight or branched lower (C1-4) alkyl optionally substituted with one or more halogens, lower (CM) alkoxy optionally substituted with one or more halogens, (C3-6) cycloalkoxy, NH2, N-lower(C1-4) alkylamino, N, N-di-lower (C1-C4) alkylamino, N-lower alkyl(C1-C4)amino carbonyl, hydroxy substituted with aromatic or non-aromatic five or six membered ring, phenyl, phenyl substituted by Cl, F, Br, I, NO2l NH2 (C1-4) alkyl or (C1-4) alkoxy (CM) perhaloalkyl, (C1-4) perhaloalkoxy wherein the broken line (- — ) is a single bond or no bond. 14. The process of claim 13 wherein the reaction of the compound of Formula VI and Formula III is carried out in a suitable solvent to give compounds of Formula I, wherein the solvent is selected from the group consisting of dimethylsulfoxide, N,N-dimethyl formamide, sulfolane, dimethylacetamide, hexamethyl phosphoramide, N-methyl-2-pyrrolidone, and ethanol. 15. The process of claim 13 wherein the reaction of compound of Formula III and Formula VI is carried out in the presence of a base, wherein the base is selected from the group consisting of potassium carbonate, cesium carbonate, sodium carbonate, triethylamine, and diisopropylamine. 16. A process for preparing a compound of Formula IX (Formula I, when X= , R7=Rg=R9=R10=H) and its pharmaceutically acceptable salts, enantiomers, diastereomers, N-oxides, prodrugs, metabolites, polymorphs, or pharmaceutically acceptable solvates thereof which comprises epoxidizing the compound of Formula II to give a compound of Formula VII, which is further reacted with a compound of Formula El (Y , R7=R8=R9=R10=H) to yield a compound of Formula VIII which on catalytic hydrogenation gives a compound of Formula IX as shown below: (Formula Removed) 17. The process of claim 16 wherein the epoxidation of compound of Formula II is carried out with a suitable peracid, wherein the peracid is selected from the group consisting of metachloroperbenzoic acid, peracetic acid, and trifluoroperacetic acid. 18. The process of claim 16 wherein the epoxidation of compound of Formula II is carried out in a suitable solvent wherein the solvent is selected from the group consisting of dichloromethane, dichloroethane, chloroform, tetrahydrofuran, acetone, and acetonitrile. 19. The process of claim 16 wherein the reaction of epoxide intermediate of Formula VII and compound of Formula III to give compound of Formula VIE is carried out in a suitable solvent wherein the solvent is selected from the group consisting of dimethylsulfoxide, N, N-dimethylformamide, sulfolane, dimethylacetamide, hexamethyl phosphoramide, and N-methyl-2-pyrrolidone. 20. The process of claim 16 wherein the reaction of the epoxide intermediate of Formula VII and a compound of Formula III is carried out in the presence of a suitable base wherein the base is selected from the group consisting of sodium hydride, cesium carbonate, potassium carbonate, and sodium carbonate. 21. The process of claim 16 wherein catalytic hydrogenation of compound of Formula VIII to give compound of Formula IX is carried out in a suitable solvent, wherein the solvent is selected from the group consisting of methanol and ethanol 22. The process of claim 16 wherein the compound of Formula VIII on nucleophilic epoxide ring opening with alcoholic hydrochloric acid gives a compound of Formula X (Formula I, when , R7=R8=R9=R10=H) (Formula Removed) 23. A process for preparing a compound of Formula XII (Formula I, X= and its pharmaceutically acceptable salts, enantiomers, diastereomers, N-oxides, prodrugs, metabolites, polymorphs, or pharmaceutically acceptable solvates thereof, which comprises reacting a compound of Formula XI (Formula I, X= 111 ) with an oxidising agent to give a compound of Formula XII as shown below: (Formula Removed) The process of claim 23 wherein the reaction of compound of Formula XI with an oxidising agent is carried out in a solvent selected from the group consisting of methanol, ethanol, acetone, and acetonitrile. 24. The process of claim 23 wherein a compound of Formula XI is oxidised to a compound of Formula XII with an oxidising agent selected from the group consisting of osmium tetraoxide and potassium permanganate. 26. A process for preparing a compound of Formula XV (Formula I, Y = and its pharmaceutically acceptable salts, enantiomers, diastereomers, N-oxides, prodrugs, metabolites, polymorphs, or pharmaceutically acceptable solvates thereof, comprising oxidising a compound of Formula XIV (Formula I, Y = with a peracid as shown below: (Formula Removed) wherein X is selected from the group consisting of (Formula Removed) where the points of attachment are depicted by hashed bonds, and where one point of attachment is bonded to the carbonyl adjacent to the nitrogen and the second point of attachment is bonded to the other carbonyl; W is O, S, SO or SO2; (Formula Removed) where m is one of the integers 2,3 or 4; RH is independently selected from H, F, Cl, Br, I, OH, straight or branched lower (C1-6) alkyl, lower (C1-6) alkoxy, lower (C1-6) perhaloalkyl, lower (C1-6) perhaloalkoxy; Y is selected from the group consisting of (Formula Removed) R1 and R2 are independently selected from H, OH, CN, NO2, Cl, F, Br, I, OR3, COR3, OCOR3, COOR3, NH2, N (R4, R5), lower (CM) alkyl, lower (CM) alkoxy, lower (C1-4) alkylthio, lower (C1-4) perhaloalkyl, lower (C1-6) perhaloalkoxy; lower (C1-4) alkoxy substituted with one or more of F, Cl, Br, I, OH, OR3 or optionally substituted groups selected from aryl, aryloxy, aralalkyl, heterocyclyl or heteroaryl the said substituents being H, F, Cl, Br, I, OH, OR3, lower (C1-4) alkyl, lower (C1-4) alkyl substitued with one or more of F, Cl, Br, I, OH or OR3, wherein R3, is selected from the group consisting of H , straight or branched C1- C6 alkyl or perhaloalkyl; R4 andR5 are independently selected from the group consisting of H, CHO, substituted or unsubstituted lower (CM) alkyl . lower (C1-4) alkoxy, COR3) COOR3, CH2CH(OR3)2, CH2COOR3, CH2CHO or (CH2)2OR3 where R3 is the same as defined above; R6, R7, R8, R9 and R10 are independently selected from H, OH, CN, NO2, Cl, F, Br, I, straight or branched lower (C1-4) alkyl optionally substituted with one or more halogens, lower (CM) alkoxy optionally substituted with one or more halogens, (C3-6) cycloalkoxy, NH2, N-lower(C1-4) alkylamino, N, N-di-lower (C1-C4) alkylamino, N-lower alkyl(C1-C4)amino carbonyl, hydroxy substituted with aromatic or non-aromatic five or six membered ring, phenyl, phenyl substituted by Cl, F, Br, I, NO2, NH2, (C1-4) allcyl or (C1-4) alkoxy (C1-4) perhaloalkyl, (C1-4) perhaloalkoxy wherein the broken line (—) is a single bond or no bond. 27. A process for preparing a compound of Formula XVII (Formula I, wherein Y = and its pharmaceutically acceptable salts, enantiomers, diastereomers, N-oxides, prodrugs, metabolites, polymoiphs, or pharmaceutically acceptable solvates thereof, comprising condensing α,ω-dicarboximides of Formula II with ethylene diamines of formula XVI as shown below: (Formula Removed) wherein X is selected from the group consisting of (Formula Removed) where the points of attachment are depicted by hashed bonds, and where one point of attachment is bonded to the carbonyl adjacent to the nitrogen and the second point of attachment is bonded to the other carbonyl; W is O, S, SO or SO2; (Formula Removed) where m is one of the integers 2,3 or 4; R11 is independently selected from H, F, Cl, Br, I, OH, straight or branched lower (C1-6) alkyl, lower (C1-6) alkoxy, lower (C1-6) perhaloalkyl, lower (C1-6) perhaloalkoxy; Y is selected from the group consisting of (Formula Removed) R1 and R2 are independently selected from H, OH, CN, NO2, Cl, F, Br, I, OR3, COR3, OCOR3, COOR3, NH2, N (R4, R5), lower (C1-4) alkyl, lower (CM) alkoxy, lower (C1-4) alkylthio, lower (CM) perhaloallcyl, lower (C1-6) perhaloalkoxy; lower (C1-4) allcoxy substituted with one or more of F, Cl, Br, I, OH, OR3 or optionally substituted groups selected from aryl, aryloxy, aralalkyl, heterocyclyl or heteroaryl the said substituents being H, F, Cl, Br, I, OH, OR3, lower (C^) alkyl, lower (C1-4) alkyl substitued with one or more of F, Cl.-Br, I, OH or OR3, wherein R3, is selected from the group consisting of H , straight or branched C1- C5 alkyl or perhaloalkyl; R4 and R5 are independently selected from the group consisting of H, CHO, substituted or unsubstituted lower (C1-4) allcyl , lower (C1-4) allcoxy, COR3, COOR3 CH2CH(OR3)2, CH2COOR3, CH2CHO or (CH2)2OR3 where R3 is the same as defined above; R6, R7, R8, R9 and R10 are independently selected from H, OH, CN, NO2, Cl, F, Br, I, straight or branched lower (CM) allcyl optionally substituted with one or more halogens, lower (CM) alkoxy optionally substituted with one or more halogens, (C3-6) cycloalkoxy, NH2, N-lower(C1-4) alkylamino, N, N-di-lower (C1-C4) alkylamino, N-lower alkyl(C1-C4)amino carbonyl, hydroxy substituted with aromatic or non-aromatic five or six membered ring, phenyl, phenyl substituted by Cl, F, Br, I, NO2, NH2, (CM) alkyl or (C1-4) allcoxy (C1-4) perhaloalkyl, (C1-4) perhaloalkoxy wherein the broken line (-—) is a single bond or no bond. 28. The process of claim 27 wherein the reaction of compound of Formula II and Formula XVI is carried out in the presence of a suitable base, wherein the base is selected from the group consisting of sodium carbonate and potassium carbonate. 29. The process of claim 27 wherein the reaction of compound of Formulae II and XVI is carried out in the presence of a solvent selected from the group consisting of dimethylsulfoxide, N, N-dimethylformamide, sulfolane, dimethylacetamide, hexamethyl phosphoramide, and N-methyl-2-pyrrolidone. 30. A process of preparing of Formula XIX (Formula I, when Y and its pharmaceutically acceptable salts, enantiomers, diastereomers, N-oxides, prodrugs, metabolites, polymorphs, or pharmaceutically acceptable solvates thereof, comprising alkylating a compound of Formula XVIII as shown below: (Formula Removed) wherein X is selected from the group consisting of (Formula Removed) where the points of attachment are depicted by hashed bonds, and where one point of attachment is bonded to the carbonyl adjacent to the nitrogen and the second point of attachment is bonded to the other carbonyl; W is O, S, SO or SO2; (Formula Removed) where m is one of the integers 2,3 or 4; RH is independently selected from H, F, Cl, Br, I, OH, straight or branched lower (C1-6) alkyl, lower (C1-6) alkoxy, lower (C1-6) perhaloalkyl, lower (C1-6) perhaloalkoxy; Y is selected from the group consisting of (Formula Removed) RI and R2 are independently selected from H, OH, CN, NO2, Cl, F, Br, I, OR3, COR3, OCOR3) COOR3, NH2, N (R,, R5), lower (Ci.4) alkyl, lower (CM) alkoxy, lower (CM) alkylthio, lower (Ci-4) perhaloalkyl, lower (Ci-6) perhaloalkoxy; lower (C1-4) alkoxy substituted with one or more of F, Cl, Br, I, OH, OR3 or optionally substituted groups selected from aryl, aryloxy, aralalkyl, heterocyclyl or heteroaryl the said substituents being H, F, Cl, Br, I, OH, OR3, lower (C1-4) alkyl, lower (C1-4) alkyl substitued with one or more of F, Cl, Br, I, OH or OR3, wherein R3, is selected from the group consisting of H , straight or branched C1- C6 alkyl or perhaloalkyl; R4 and R5 are independently selected from the group consisting of H, CHO, substituted or unsubstituted lower (C1-4) alkyl , lower (CM) alkoxy, COR3, COOR3, CH2CH(OR3)2, CH2COOR3, CH2CHO or (CH2)2OR3 where R3 is the same as defined above; R6, R7, R8, R9 and RIO are independently selected from H, OH, CN, NO2, Cl, F, Br, I, straight or branched lower (C1-4) alkyl optionally substituted with one or more halogens, lower (C1-4) alkoxy optionally substituted with one or more halogens, (C3-6) cycloalkoxy, NH2, N-lower(C1-4) alkylamino, N, N-di-lower (C1-C4) alkylamino, N-lower alkyl(C1-C4)amino carbonyl, hydroxy substituted with aromatic or non-aromatic five or six membered ring, phenyl, phenyl substituted by Cl, F, Br, I, NO2, NH2, (C1-4) aUcyl or (C1-4) alkoxy (C1-4) perhaloalkyl, (C1-4) perhaloalkoxy wherein the broken line (-—) is a single bond or no bond. 31. The process of claim 30 wherein a compound of Formula XVIII is alkylated in a suitable organic solvent wherein the solvent is selected from the group consisting of dimethylsulfoxide, N, N-dimethylformamide, sulfolane, dimethylacetamide, hexamethyl phosphoramide, and N-methyl-2-pyrrolidone. 32. The process of claim 30 wherein the allcylation is canied out in the presence of an inorganic base selected from the group consisting of potassium carbonate, sodium carbonate, and sodium hydride. 33. A process for preparing a compound of Formula XX (Formula I, when Y and its pharmaceutically acceptable salts, enantiomers, diastereomers, N-oxides, prodrugs, metabolites, polymorphs, or pharmaceutically acceptable solvates thereof, comprising reacting a compound of Formula XVIII with oxalyl chloride as shown below: (Formula Removed) wherein X is selected from the group consisting of (Formula Removed) where the points of attachment are depicted by hashed bonds, and where one point of attachment is bonded to the carbonyl adjacent to the nitrogen and the second point of attachment is bonded to the other carbonyl; WisO, S,SOorSO2; (Formula Removed) where m is one of the integers 2,3 or 4; R11 is independently selected from H, F, Cl, Br, I, OH, straight or branched lower (C1-6) alkyl, lower (C1-6) alkoxy, lower (C1-6) perhaloalkyl, lower (C1-6) perhaloalkoxy; Y is selected from the group consisting of (Formula Removed) Ri and R2 are independently selected from H, OH, CN, NO2, Cl, F, Br, I, OR3, COR3l OCOR3, COOR3, NH2, N (R4, R5), lower (C1-4) alkyl, lower (C1-4) alkoxy, lower (C1-4) alkylthio, lower (CM) perhaloalkyl, lower (C1-6) perhaloalkoxy; lower (C1-4) alkoxy substituted with one or more of F, Cl, Br, I, OH, OR3 or optionally substituted groups selected from aryl, aryloxy, aralalkyl, heterocyclyl or heteroaryl the said substituents being H, F, Cl, Br, I, OH, OR3, lower (CM) alkyl, lower (C1-4) alkyl substitued with one or more of F, Cl, Br, I, OH or OR3, wherein R3) is selected from the group consisting of H , straight or branched C1- C= alkyl or perhaloalkyl; R4 and R5 are independently selected from the group consisting of H, CHO, substituted or unsubstituted lower (C1-4) alkyl , lower (C1-4) alkoxy, COR3, COOR3, CH2CH(OR3)2, CH2COOR3, CH2CHO or (CH2)2OR3 where R3 is the same as defined above; R6, R7, R8, R9 and R10 are independently selected from H, OH, CN, NO2, Cl, F, Br, I, straight or branched lower (C1-4) alkyl optionally substituted with one or more halogens, lower (C1-4) alkoxy optionally substituted with one or more halogens, (C3-6) cycloalkoxy, NH2, N-lower(C1-4) alkylamino, N, N-di-lower (C1-C4) alkylamino, N-lower alkyl(C1-C4)amino carbonyl, hydroxy substituted with aromatic or non-aromatic five or six membered ring, phenyl, phenyl substituted by Cl, F, Br, I, NO2, NH2, (C1-4) alkyl or (C1-4) alkoxy (C1-4) perhaloalkyl, (C1-4) perhaloalkoxy wherein the broken line (-—) is a single bond or no bond. 34. The process of claim 33 wherein Formula XVIII is converted to its dioxo analog of Formula XX upon treatment with oxalyl chloride in the presence of a suitable organic base wherein the base is selected from the group consisting of triethylamine and diisopropyl ethylamine. 35. The process of Claim 33 wherein the reaction of compound of Formula XVIII is carried out to a compound of Formula XX with oxalyl chloride in a suitable organic solvent wherein the solvent is selected from the group consisting of dichloromethane, dichloroethane, chloroform, and tetrahydrofuran. 36. A process for preparing a compound Formula XXII (Formula I, when X = A = -(CH2)3, and its pharmaceutically acceptable salts, enantiomers, diastereomers, N-oxides, prodrugs, metabolites, polymorphs, or pharmaceutically acceptable solvates thereof, comprising condensing maleic anhydride .with substituted phenylpiperazine of Formula IV (A = (CH2)3 Y = as shown below: (Formula Removed) .—. wherein X is selected from the group consisting of (Formula Removed) where the points of attachment are depicted by hashed bonds, and where one point of attachment is bonded to the carbonyl adjacent to the nitrogen and the second point of attachment is bonded to the other carbonyl; W is O, S, SO or SO2; (Formula Removed) where m is one of the integers 2,3 or 4; RH is independently selected from H, F, Cl, Br, I, OH, straight or branched lower (Ci-g) alkyl, lower (Ci.G) allcoxy, lower (Ci-6) perhaloalkyl, lower (Ci.6) perhaloalkoxy; Y is selected from the group consisting of (Formula Removed) R1and R2 are independently selected from H, OH, CN, NO2, Cl, F, Br, I, OR3, COR3, OCOR3, COOR3, NH2, N (R4, R5), lower (C1-4) alkyl, lower (C1-4) allcoxy, lower (C1-4) alkylthio, lower (C1-4) perhaloalkyl, lower (C1-6) perhaloalkoxy; lower (C1-4) allcoxy substituted with one or more of F, Cl, Br, I, OH, OR3 or optionally substituted groups selected from aryl, aryloxy, aralalkyl, heterocyclyl or heteroaryl the said substituents being H, F, Cl, Br, I, OH, OR3, lower (C1-4) alkyl, lower (C1-4) alkyl substitued with one or more of F, Cl, Br, I, OH or OR3, wherein R3, is selected from the group consisting of H , straight or branched C1- C6 alkyl or perhaloalkyl; R4 and R5 are independently selected from the group consisting of H, CHO, substituted or unsubstituted lower (C1-4) alkyl , lower (C1-4) allcoxy, COR3, COOR3, CH2CH(OR3)2, CH2COOR3, CH2CHO or (CH2)2OR3 where R3 is the same as defined above; R6, R7, R8, R9 and R10 are independently selected from H, OH, CN, NO2, Cl, F, Br, I, straight or branched lower (C1-4) alkyl optionally substituted with one or more halogens, lower (C1-4) alkoxy optionally substituted with one or more halogens, (C3-6) cycloalkoxy, NH2, N-lower(C1-4) alkylamino, N, N-di-lower (C1-C4) alkylamino, N-lower alkyl(C1-C4)amino carbonyl, hydroxy substituted with aromatic or non-aromatic five or six membered ring, phenyl, phenyl substituted by Cl, F, Br, I, NO2, NH2, (CM) alkyl or (C1-4) alkoxy (C1-4) perhaloalkyl, (C1-4) perhaloalkoxy wherein the broken line (—) is a single bond or no bond.