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Amino Substituted 3 Heteroaroylamino Propionic Acid Derivatives And Their Use As Pharmaceuticals
Abstract: 101130405060Amino substituted 3 heteroaroylamino propionic acid derivatives and their use as pharmaceuticals The present invention relates to compounds of the formula (I) wherein A D E G R R R R R and R have the meanings indicated in the claims which are valuable pharmaceutical active compounds. They are inhibitors of the protease cathepsin A and are useful for the treatment of diseases such as atherosclerosis heart failure renal diseases liver diseases or inflammatory diseases for example. The invention furthermore relates to processes for the preparation of the compounds of the formula I their use and pharmaceutical compositions comprising them.
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
28 June 2013
Publication Number
02/2015
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
patent@depenning.com
Parent Application
Applicants
SANOFI
54 rue La Boétie
F 75008 Paris
Inventors
1. RUF Sven
c/o Sanofi Aventis Deutschland GmbH
65926 Frankfurt am Main
2. SADOWSKI Thorsten
c/o Sanofi Aventis Deutschland GmbH
65926 Frankfurt am Main
3. HORSTICK Georg
c/o Sanofi Aventis Deutschland GmbH
65926 Frankfurt am Main
4. SCHREUDER Herman
c/o Sanofi Aventis Deutschland GmbH
65926 Frankfurt am Main
5. BUNING Christian
c/o Sanofi Aventis Deutschland GmbH
65926 Frankfurt am Main
6. OLPP Thomas
c/o Sanofi Aventis Deutschland GmbH
65926 Frankfurt am Main
7. WIRTH Klaus
c/o Sanofi Aventis Deutschland GmbH
65926 Frankfurt am Main
Specification
SOFTCOPY ATTACHED IN PDF
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 5110-CHENP-2013 POWER OF ATTORNEY 28-06-2013.pdf | 2013-06-28 |
| 1 | abstract5110-CHENP-2013.jpg | 2014-12-04 |
| 2 | 5110-CHENP-2013 FORM-5 28-06-2013.pdf | 2013-06-28 |
| 2 | 5110-CHENP-2013 CORRESPONDENCE OTHERS 10-12-2013.pdf | 2013-12-10 |
| 3 | 5110-CHENP-2013 FORM-3 28-06-2013.pdf | 2013-06-28 |
| 3 | 5110-CHENP-2013 FORM-3 10-12-2013.pdf | 2013-12-10 |
| 4 | 5110-CHENP-2013 FORM-2 FIRST PAGE 28-06-2013.pdf | 2013-06-28 |
| 4 | 5110-CHENP-2013.pdf | 2013-07-01 |
| 5 | 5110-CHENP-2013 FORM-1 28-06-2013.pdf | 2013-06-28 |
| 5 | 5110-CHENP-2012 PCT PUBLICATION 28-06-2013.pdf | 2013-06-28 |
| 6 | 5110-CHENP-2013 DESCRIPTION (COMPLETE) 28-06-2013.pdf | 2013-06-28 |
| 6 | 5110-CHENP-2013 CLAIMS 28-06-2013.pdf | 2013-06-28 |
| 7 | 5110-CHENP-2013 CORRESPONDENCE OTHERS 28-06-2013.pdf | 2013-06-28 |
| 7 | 5110-CHENP-2013 CLAIMS SIGNATURE LAST PAGE 28-06-2013.pdf | 2013-06-28 |
| 8 | 5110-CHENP-2013 CORRESPONDENCE OTHERS 28-06-2013.pdf | 2013-06-28 |
| 8 | 5110-CHENP-2013 CLAIMS SIGNATURE LAST PAGE 28-06-2013.pdf | 2013-06-28 |
| 9 | 5110-CHENP-2013 DESCRIPTION (COMPLETE) 28-06-2013.pdf | 2013-06-28 |
| 9 | 5110-CHENP-2013 CLAIMS 28-06-2013.pdf | 2013-06-28 |
| 10 | 5110-CHENP-2012 PCT PUBLICATION 28-06-2013.pdf | 2013-06-28 |
| 10 | 5110-CHENP-2013 FORM-1 28-06-2013.pdf | 2013-06-28 |
| 11 | 5110-CHENP-2013 FORM-2 FIRST PAGE 28-06-2013.pdf | 2013-06-28 |
| 11 | 5110-CHENP-2013.pdf | 2013-07-01 |
| 12 | 5110-CHENP-2013 FORM-3 28-06-2013.pdf | 2013-06-28 |
| 12 | 5110-CHENP-2013 FORM-3 10-12-2013.pdf | 2013-12-10 |
| 13 | 5110-CHENP-2013 FORM-5 28-06-2013.pdf | 2013-06-28 |
| 13 | 5110-CHENP-2013 CORRESPONDENCE OTHERS 10-12-2013.pdf | 2013-12-10 |
| 14 | abstract5110-CHENP-2013.jpg | 2014-12-04 |
| 14 | 5110-CHENP-2013 POWER OF ATTORNEY 28-06-2013.pdf | 2013-06-28 |