Abstract: The present disclosure relates to a composition comprising piperine, and rutin which at particular weight ratios exhibits enhanced inhibition of inflammation. Also provided are methods and uses of said composition.
Claims:1. A composition comprising:
a. piperine; and
b. rutin,
wherein piperine to rutin w/w ratio in said composition is in the range of 1:1 to 16:1.
2. The composition as claimed in claim 1, wherein piperine weight percentage in said composition is in the range of 0.002 % to 0.008 %, and rutin weight percentage in said composition is in the range of 0.0005% to 0.002%.
3. The composition as claimed in claim 1, wherein piperine to rutin w/w ratio in said composition is 16:1.
4. The composition as claimed in claim 3, wherein piperine weight percentage in said composition is 0.008 %, and rutin weight percentage in said composition is in 0.0005%.
5. The composition as claimed in claim 1, wherein piperine to rutin w/w ratio in said composition is 6:1.
6. The composition as claimed in claim 5, wherein piperine weight percentage in said composition is 0.006%, and rutin weight percentage in said composition 0.001%.
7. The composition as claimed in claim 1, wherein piperine to rutin w/w ratio in said composition is 4:1.
8. The composition as claimed in claim 7, wherein piperine weight percentage in said composition is 0.005%, and rutin weight percentage in said composition 0.000125%.
9. The composition as claimed in claim 1, wherein piperine to rutin w/w ratio in said composition is 2.67:1.
10. The composition as claimed in claim 9, wherein piperine weight percentage in said composition is 0.004%, and rutin weight percentage in said composition 0.0015%.
11. The composition as claimed in claim 1, wherein piperine to rutin w/w ratio in said composition is 1:1.
12. The composition as claimed in claim 11, wherein piperine weight percentage in said composition is 0.002%, and rutin weight percentage in said composition 0.002%.
13. The composition as claimed in any of the claims 1-12, further comprising carriers, diluents, and excipients.
14. A method of preparing a composition as claimed in any of the claims 1-13.
15. A method to reduce inflammation, said method comprising:
a. obtaining a composition as claimed in any of the claims 1-13; and
b. contacting said composition with site of inflammation,
wherein said method reduces inflammation.
, Description:As Attached
| # | Name | Date |
|---|---|---|
| 1 | 201641011530-IntimationOfGrant26-06-2023.pdf | 2023-06-26 |
| 1 | Form 5 [31-03-2016(online)].pdf | 2016-03-31 |
| 2 | 201641011530-PatentCertificate26-06-2023.pdf | 2023-06-26 |
| 2 | Form 3 [31-03-2016(online)].pdf | 2016-03-31 |
| 3 | Drawing [31-03-2016(online)].pdf | 2016-03-31 |
| 3 | 201641011530-Written submissions and relevant documents [06-06-2023(online)].pdf | 2023-06-06 |
| 4 | Description(Complete) [31-03-2016(online)].pdf | 2016-03-31 |
| 4 | 201641011530-FORM-26 [23-05-2023(online)].pdf | 2023-05-23 |
| 5 | Other Patent Document [20-05-2016(online)].pdf | 2016-05-20 |
| 5 | 201641011530-Correspondence to notify the Controller [19-05-2023(online)].pdf | 2023-05-19 |
| 6 | Form 26 [20-05-2016(online)].pdf | 2016-05-20 |
| 6 | 201641011530-US(14)-HearingNotice-(HearingDate-24-05-2023).pdf | 2023-04-24 |
| 7 | Other Patent Document [22-06-2016(online)].pdf | 2016-06-22 |
| 7 | 201641011530-Response to office action [23-06-2022(online)].pdf | 2022-06-23 |
| 8 | Form 26 [22-06-2016(online)].pdf | 2016-06-22 |
| 8 | 201641011530-FER.pdf | 2021-10-17 |
| 9 | 201641011530-Power of Attorney-270616.pdf | 2016-07-29 |
| 9 | 201641011530-Response to office action [16-07-2021(online)].pdf | 2021-07-16 |
| 10 | 201641011530-Form 1-270616.pdf | 2016-07-29 |
| 10 | 201641011530-FORM 18 [27-03-2020(online)].pdf | 2020-03-27 |
| 11 | 201641011530-Correspondence-PA-270616.pdf | 2016-07-29 |
| 12 | 201641011530-Form 1-270616.pdf | 2016-07-29 |
| 12 | 201641011530-FORM 18 [27-03-2020(online)].pdf | 2020-03-27 |
| 13 | 201641011530-Power of Attorney-270616.pdf | 2016-07-29 |
| 13 | 201641011530-Response to office action [16-07-2021(online)].pdf | 2021-07-16 |
| 14 | 201641011530-FER.pdf | 2021-10-17 |
| 14 | Form 26 [22-06-2016(online)].pdf | 2016-06-22 |
| 15 | 201641011530-Response to office action [23-06-2022(online)].pdf | 2022-06-23 |
| 15 | Other Patent Document [22-06-2016(online)].pdf | 2016-06-22 |
| 16 | 201641011530-US(14)-HearingNotice-(HearingDate-24-05-2023).pdf | 2023-04-24 |
| 16 | Form 26 [20-05-2016(online)].pdf | 2016-05-20 |
| 17 | 201641011530-Correspondence to notify the Controller [19-05-2023(online)].pdf | 2023-05-19 |
| 17 | Other Patent Document [20-05-2016(online)].pdf | 2016-05-20 |
| 18 | 201641011530-FORM-26 [23-05-2023(online)].pdf | 2023-05-23 |
| 18 | Description(Complete) [31-03-2016(online)].pdf | 2016-03-31 |
| 19 | Drawing [31-03-2016(online)].pdf | 2016-03-31 |
| 19 | 201641011530-Written submissions and relevant documents [06-06-2023(online)].pdf | 2023-06-06 |
| 20 | Form 3 [31-03-2016(online)].pdf | 2016-03-31 |
| 20 | 201641011530-PatentCertificate26-06-2023.pdf | 2023-06-26 |
| 21 | Form 5 [31-03-2016(online)].pdf | 2016-03-31 |
| 21 | 201641011530-IntimationOfGrant26-06-2023.pdf | 2023-06-26 |
| 1 | SEARCHSTRATEGY1E_15-01-2021.pdf |